A supercritical extraction equipment for pharmaceutical use

Abstract

The present invention discloses a supercritical extraction device dedicated to pharmaceutical production, comprising a base plate, the top of which is detachably connected to a protective support shell by screws, the top of which is fixedly connected to a reaction extraction kettle for extracting medicines, the interior of which is provided with a mixing and stirring assembly, the interior of which is provided with a control assembly for controlling the stirring assembly, the mixing and stirring assembly comprising an outer ring rotating sleeve, an inner ring rotating rod penetrating the outer ring rotating sleeve, and a retractable stirring assembly fixed to the outer side of the inner ring rotating rod. The present invention can improve the mixing degree of internal gas and material, improve the extraction efficiency of medicines, facilitate full extraction, and improve the utilization rate of medicines through the outer ring rotating sleeve, the inner ring rotating rod, and the retractable stirring assembly. The present invention can improve the mixing degree of internal gas and material through the outer ring rotating sleeve, the inner ring rotating rod, and the retractable stirring assembly, improve the extraction efficiency of medicines, facilitate full extraction, and improve the utilization rate of medicines. Through the dispersion chimney and the bulk pipe, the supercritical fluid and material can be dispersed and input to fully extract the medicines.

Description

Technical Field

[0001] The invention relates to the field of drug extraction equipment, and in particular to a supercritical extraction equipment dedicated to pharmaceuticals. Background Art

[0002] The chemical composition of traditional Chinese medicine is very complex. It contains multiple effective ingredients, ineffective ingredients, and toxic ingredients. Extracting the effective ingredients and further separating and purifying them to obtain effective monomers is an important content in the field of traditional Chinese medicine research. Traditional Chinese medicine extraction is to use some technologies to extract the effective ingredients to the maximum extent, so that the intrinsic quality and clinical treatment effect of traditional Chinese medicine preparations can be improved, and the effect of traditional Chinese medicine can be maximized. Supercritical is a supercritical fluid, which is a physical state between gas and liquid that is neither gaseous nor liquid. This substance can only exist when its temperature and pressure exceed the critical point. The density of supercritical fluid is large, similar to that of liquid, and its viscosity is closer to that of gas. Therefore, supercritical fluid is an ideal extractant. When extracting traditional Chinese medicine, the relationship between the solubility of supercritical fluid and its density can be used to affect the solubility of supercritical fluid. The optimal proportion of mixed components can be obtained by controlling the conditions, and then the supercritical fluid is turned into ordinary gas by the method of reducing pressure and raising temperature, and the extracted medicine is basically precipitated, thereby achieving the purpose of separation and purification.

[0003] Under the supercritical state, the supercritical fluid needs to be fully in contact with the Chinese medicine so that it can selectively extract the components of polarity, boiling point and molecular weight in sequence. However, most of the existing extraction equipment is not convenient for fully mixing the supercritical fluid and the medicine, the extraction efficiency is low, and insufficient extraction is prone to occur.

[0004] Therefore, it is necessary to invent a special supercritical extraction equipment for pharmaceutical use to solve the above problems. Summary of the invention

[0005] The purpose of the present invention is to provide a supercritical extraction device dedicated to pharmaceutical production. Through an outer ring rotating sleeve, an inner ring rotating rod and a retractable stirring component, the mixing degree of internal gas and material can be improved, the extraction efficiency of medicines is improved, and it is convenient to fully extract and improve the utilization rate of medicines. Through a dispersion chimney, the supercritical fluid can be dispersed and input, which is convenient for mixing with the internal medicines and fully extracting the medicines, so as to solve the problem that most extraction devices in the prior art are not convenient for fully mixing the supercritical fluid and the medicines, the extraction efficiency is low, and insufficient extraction is prone to occur.

[0006] In order to achieve the above-mentioned object, the present invention provides the following technical solutions: a supercritical extraction device dedicated to pharmaceutical use, comprising a base plate, the top of the base plate is detachably connected to a protective support shell by screws, the top of the protective support shell is fixedly connected to a reaction extraction kettle for extracting drugs, a mixing and stirring component is arranged inside the reaction extraction kettle, a control component for controlling the stirring component is arranged inside the protective support shell, and the mixing and stirring component comprises an outer ring rotating sleeve, an inner ring rotating rod penetrating the outer ring rotating sleeve, and a retractable stirring component fixed to the outside of the inner ring rotating rod;

[0007] The control component includes a motor arranged inside the protective support shell, the top of the base plate is located inside the protective support shell and is fixedly connected to two symmetrically distributed vertical plates, the motor is installed on the outside of one of the vertical plates, the output end of the motor is fixedly connected to a power bevel gear through a coupling, the upper and lower sides of the power bevel gear are respectively meshed and connected with an outer ring driven gear and an inner ring driven gear, the outer ring driven gear is fixedly connected to the outside of an outer ring rotating sleeve, the inner ring driven gear is fixedly connected to the outside of an inner ring rotating rod, the outer ring rotating sleeve is rotatably connected to the inner ring rotating rod, a rotating bearing is connected between the outer ring rotating sleeve and the inner ring rotating rod, the outer side of the outer ring rotating sleeve is rotatably connected to a first fixed ring fixed on the protective support shell, the outer side of the inner ring rotating rod is rotatably connected to a second fixed ring fixed on the protective support shell, and the first fixed ring and the second fixed ring are both fixed on the inner side of the other vertical plate.

[0008] As a preferred solution of the present invention, the outer side of the top of the outer ring rotating sleeve is fixedly connected to an outer ring bottom rod, the end of the outer ring bottom rod is fixedly connected to an outer ring lower spiral blade, the top of the outer ring lower spiral blade is fixedly connected to an outer ring upper spiral blade, a top bearing is arranged in the middle of the inner top wall of the reaction extraction kettle, a rotating block is rotatably connected inside the top bearing, and an outer ring top rod is fixedly connected between the rotating block and the outer ring upper spiral blade.

[0009] As a preferred solution of the present invention, the outer side of the inner ring rotating rod is fixedly connected to the inner ring bottom rod by screws, the end of the inner ring bottom rod is fixedly connected to the inner ring lower spiral leaf by screws, the top of the inner ring lower spiral leaf is fixedly connected to the inner ring upper spiral leaf, the top of the inner ring upper spiral leaf is fixedly connected to the inner ring rotating rod by screws with an inner ring top rod, the connection between the inner ring lower spiral leaf and the inner ring upper spiral leaf is provided with an inner ring middle rod fixedly connected to the inner ring rotating rod by screws, the bottom of the inner ring rotating rod is rotatably connected to a base, and the top of the inner ring rotating rod is rotatably connected to the top bearing.

[0010] As a preferred solution of the present invention, the lower spiral blades of the outer ring are arranged clockwise, the upper spiral blades of the outer ring are arranged counterclockwise, the lower spiral blades of the inner ring are arranged counterclockwise, and the upper spiral blades of the inner ring are arranged clockwise, the lower spiral blades of the outer ring are adapted to the lower spiral blades of the inner ring, and the upper spiral blades of the outer ring are adapted to the upper spiral blades of the inner ring.

[0011] As a preferred solution of the present invention, the number of the retractable stirring components is set to be multiple, and the multiple retractable stirring components are staggered on both sides of the inner ring rotating rod, and the outer ends of the retractable stirring components extend to the inner side of the lower spiral blade of the outer ring or the upper spiral blade of the outer ring, so that the retractable stirring components do not interfere with the lower spiral blade of the outer ring or the upper spiral blade of the outer ring.

[0012] As a preferred solution of the present invention, the retractable stirring assembly is provided with a limiting groove near the inner end of the inner ring rotating rod, a slot is provided on the outer side of the limiting groove, a sliding block is slidably connected inside the limiting groove, a push rod extending to the outside of the slot is fixedly connected on the outer side of the sliding block, support rods are hinged on both sides of the outer end of the push rod, stirring rods are hinged on both sides of the outer end of the retractable stirring assembly, and the two stirring rods are hinged to the support rods on both sides respectively.

[0013] As a preferred solution of the present invention, the inner top and inner bottom walls of the limiting groove are provided with limiting slide grooves, the upper and lower sides of the sliding block are fixedly connected with protrusions slidably connected to the limiting slide grooves, and the rear side of the sliding block is fixedly connected with an elastic part fixedly connected to the inner wall of the retractable stirring assembly.

[0014] As a preferred embodiment of the present invention, the reaction extraction kettle is provided with an extraction chamber and a feed chamber, an isolation plate is fixedly connected between the extraction chamber and the feed chamber, a plurality of evenly distributed feed holes are provided inside the isolation plate, and a dispersion chimney is fixedly connected at the outlet of each of the feed holes, a one-way valve is installed inside each of the dispersion chimneys, and a top plate is fixedly connected to the top of the dispersion chimney.

[0015] As a preferred solution of the present invention, an air inlet is arranged on the side of the extraction chamber, and an outlet is arranged on the bottom side of the extraction chamber. One-way valves are installed inside the air inlet, feed port and outlet, and the isolation plate is inclined toward the outlet.

[0016] As a preferred solution of the present invention, the inner ring rotating rod extends to the outside of the top of the outer ring rotating sleeve, and a feed pipe is fixedly connected to the middle of the top of the reaction extraction kettle, a pump group is arranged inside the feed pipe, the feed pipe is sealed and connected to the inner ring rotating rod, and the feed pipe is rotatably connected to the inner ring rotating rod, and a feed channel extending to the bottom of the retractable stirring assembly is opened inside the inner ring rotating rod;

[0017] A feed groove is provided inside the retractable stirring component near the inner ring rotating rod, and circulation grooves are provided on the upper and lower sides of the retractable stirring component. A distribution groove is connected between the circulation groove and the feed groove, and a return spring is fixedly connected to the end of the feed groove away from the retractable stirring component, and a stopper is slidably connected to the inside of the feed groove, and the end of the stopper away from the inner ring rotating rod is fixedly connected to the sliding rod extending to the outside of the retractable stirring component, and the other end of the return spring is fixedly connected to the stopper, and a limit rod fixed to the inner wall of the feed groove is penetrated inside the return spring;

[0018] The outlet of the circulation trough is connected to a bulk material pipe, and the bulk material pipe is configured as a hose. First support rods are hinged on both sides of the retractable stirring assembly, and a fixing plate is fixedly connected between the first support rod and the bulk material pipe. A cross bar is fixedly connected to the end of the sliding rod, and second support rods are hinged at both ends of the cross bar, and the other ends of the two second support rods are hinged to the two first support rods respectively.

[0019] In the above technical solution, the technical effects and advantages provided by the present invention are:

[0020] 1. The outer ring rotating sleeve rotates clockwise, and the inner ring rotating rod rotates counterclockwise, which can make the outer ring lower spiral blade and the inner ring lower spiral blade drive the gas or object to move upward, and at the same time, make the outer ring upper spiral blade and the inner ring upper spiral blade drive the gas or object to move downward, so that the internal material is fully stirred, and the outer ring rotating sleeve and the inner ring rotating rod rotate in opposite directions, which can improve the mixing degree of the internal gas and material, improve the extraction efficiency of the medicine, and facilitate full extraction and improve the utilization rate of the medicine. Multiple retractable stirring components can be automatically unfolded while rotating, which is conducive to further improving the stirring effect and the internal extraction efficiency. The outer ring upper spiral blade and the outer ring lower spiral blade can scrape the attachments on the inner wall of the device;

[0021] 2. The feed chamber allows the supercritical fluid to enter the dispersion chimney through the feed hole, and then enter the extraction chamber through the dispersion chimney, so that the supercritical fluid can be dispersed and input, which is convenient for mixing with the internal drugs, and the top plate can prevent the top materials from entering the dispersion chimney;

[0022] 3. By inputting the material into the inner ring rotating rod and then into the retractable stirring assembly, the block slides outward under the extrusion of the material and the action of centrifugal force, so that the two bulk tubes rotate upward or downward. Under the rotation of the inner ring rotating rod, the material can be dispersed inside the device, so that the material is fully mixed with the supercritical fluid, thereby improving the use efficiency of the device. After the reaction is completed, under the action of the spring, it can be driven to reset quickly, and then the bulk tube, the first support rod and the second support rod can be vibrated, so that the attachments solidified on their surfaces can be shaken off, which is convenient for cleaning. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present invention. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0024] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0025] Figure 2 It is a schematic diagram of the internal structure of the present invention;

[0026] Figure 3 This is a schematic diagram of the connection structure between the mixing and stirring component and the control component of the present invention;

[0027] Figure 4 It is a schematic diagram of the connection structure between the outer ring rotating sleeve and the inner ring rotating rod of the present invention;

[0028] Figure 5 It is a schematic diagram of the connection structure between the inner ring rotating rod and the retractable stirring assembly of the present invention;

[0029] Figure 6 It is a schematic diagram of the connection structure between the outer ring lower spiral blade and the outer ring rotating sleeve of the present invention;

[0030] Figure 7 It is a schematic cross-sectional structure diagram of the retractable stirring assembly of the present invention;

[0031] Figure 8 It is a schematic diagram of the connection structure between the retractable stirring assembly and the sliding block of the present invention;

[0032] Fig. 9 It is a schematic diagram of the three-dimensional structure of the dispersion chimney of the present invention;

[0033] Fig.10 For the present invention Figure 3 The enlarged structural diagram at A in the middle;

[0034] Fig.11A three-dimensional diagram of a connection method of the second embodiment of the retractable stirring assembly of the present invention;

[0035] Fig.12 A three-dimensional diagram of another connection method of the second embodiment of the retractable stirring assembly of the present invention;

[0036] Fig.13 It is a cross-sectional structural schematic diagram of a second embodiment of a retractable stirring assembly of the present invention;

[0037] Fig.14 It is a schematic diagram of the connection structure between the sliding rod and the return spring of the present invention;

[0038] Fig.15 It is a stereoscopic view of a second embodiment of the connection between the inner ring rotating rod and the outer ring rotating sleeve of the present invention.

[0039] Description of reference numerals:

[0040] 1. Base plate; 2. Protective support shell; 3. Reaction extraction kettle; 4. Outer ring rotating sleeve; 5. Inner ring rotating rod; 6. Retractable stirring assembly;

[0041] 21. Motor; 22. Power bevel gear; 23. First fixing collar; 24. Second fixing collar;

[0042] 31. extraction chamber; 32. feed chamber; 33. isolation plate; 34. air inlet; 35. feed inlet; 37. discharge port; 38. dispersion chimney; 310. top plate;

[0043] 41. Outer ring driven gear; 42. Outer ring bottom rod; 43. Outer ring lower spiral blade; 44. Outer ring upper spiral blade; 45. Top bearing; 46. Outer ring top rod;

[0044] 51. Inner ring driven gear; 52. Inner ring bottom rod; 53. Inner ring lower spiral blade; 54. Inner ring upper spiral blade; 55. Base; 56. Inner ring top rod; 57. Inner ring middle rod;

[0045] 61. elastic member; 62. sliding block; 63. push rod; 64. supporting rod; 65. stirring rod;

[0046] 601, feed trough; 602, distribution trough; 603, circulation trough; 604, stopper; 605, slide rod; 606, return spring; 607, first support rod; 608, bulk material pipe; 609, fixing plate; 610, cross bar; 611, second support rod. DETAILED DESCRIPTION

[0047] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below with reference to the accompanying drawings.

[0048] The present invention provides Figure 1-10 A pharmaceutical-specific supercritical extraction device is shown, comprising a base plate 1, a protective support shell 2 is detachably connected to the top of the base plate 1 by screws, a reaction extraction kettle 3 for extracting drugs is fixedly connected to the top of the protective support shell 2, a mixing and stirring assembly is arranged inside the reaction extraction kettle 3, a control assembly for controlling the stirring assembly is arranged inside the protective support shell 2, and the mixing and stirring assembly comprises an outer ring rotating sleeve 4, an inner ring rotating rod 5 penetrating the outer ring rotating sleeve 4, and a retractable stirring assembly 6 fixed to the outside of the inner ring rotating rod 5;

[0049] The control component includes a motor 21 arranged inside the protective support shell 2. The top of the base plate 1 is located inside the protective support shell 2 and is fixedly connected to two symmetrically distributed vertical plates. The motor 21 is installed on the outside of one of the vertical plates. The output end of the motor 21 is fixedly connected to a power bevel gear 22 through a coupling. The upper and lower sides of the power bevel gear 22 are respectively meshed with an outer ring driven gear 41 and an inner ring driven gear 51. The outer ring driven gear 41 is fixedly connected to the outside of the outer ring rotating sleeve 4, and the inner ring driven gear 51 is fixedly connected to the outside of the inner ring rotating rod 5. The outer ring rotating sleeve 4 is rotatably connected to the inner ring rotating rod 5, and a rotating bearing is connected between the outer ring rotating sleeve 4 and the inner ring rotating rod 5. The outer side of the outer ring rotating sleeve 4 is rotatably connected to a first fixed ring 23 fixed on the protective support shell 2, and the outer side of the inner ring rotating rod 5 is rotatably connected to a second fixed ring 24 fixed on the protective support shell 2. The first fixed ring 23 and the second fixed ring 24 are both fixed on the inner side of the other vertical plate.

[0050] Specifically, when in use, the user can start the motor 21, and the motor 21 drives the power bevel gear 22 to rotate. The power bevel gear 22 drives the outer ring rotating sleeve 4 to rotate clockwise through the outer ring driven gear 41, and drives the inner ring rotating rod 5 to rotate counterclockwise through the inner ring driven gear 51. The outer ring rotating sleeve 4 and the inner ring rotating rod 5 are rotationally connected via a rotating bearing, and the first fixed ring 23 can support the outer ring rotating sleeve 4, so that the outer ring rotating sleeve 4 rotates inside the first fixed ring 23 to prevent the outer ring rotating sleeve 4 from sliding on the outside of the inner ring rotating rod 5, and the second fixed ring 24 can support the inner ring rotating rod 5.

[0051] In the above structure, the outer side of the top of the outer ring rotating sleeve 4 is fixedly connected to the outer ring bottom rod 42, the end of the outer ring bottom rod 42 is fixedly connected to the outer ring lower spiral leaf 43, the top of the outer ring lower spiral leaf 43 is fixedly connected to the outer ring upper spiral leaf 44, and a top bearing 45 is arranged in the middle of the inner top wall of the reaction extraction kettle 3, the inside of the top bearing 45 is rotatably connected to a rotating block, and an outer ring top rod 46 is fixedly connected between the rotating block and the outer ring upper spiral leaf 44.

[0052] Specifically, while the outer ring rotating sleeve 4 rotates, the outer ring rotating sleeve 4 drives the outer ring lower spiral blade 43 and the outer ring upper spiral blade 44 to rotate, and then drives the rotating block to rotate inside the top bearing 45, which greatly reduces the resistance of the inner ring rotating rod 5, which is beneficial to stirring the internal objects, and the outer sides of the outer ring lower spiral blade 43 and the outer ring upper spiral blade 44 are in contact with the inner wall of the reaction extraction kettle 3, which is beneficial to fully stirring the material on the inner wall, and the stability of the outer ring lower spiral blade 43 and the outer ring upper spiral blade 44 can be enhanced by the outer ring bottom rod 42 and the outer ring top rod 46.

[0053] As a further optimization of the present invention, the outer side of the inner ring rotating rod 5 is fixedly connected to the inner ring bottom rod 52 by screws, the end of the inner ring bottom rod 52 is fixedly connected to the inner ring lower spiral leaf 53 by screws, the top of the inner ring lower spiral leaf 53 is fixedly connected to the inner ring upper spiral leaf 54, the top of the inner ring upper spiral leaf 54 is fixedly connected to the inner ring rotating rod 5 by screws with an inner ring top rod 56, the connection between the inner ring lower spiral leaf 53 and the inner ring upper spiral leaf 54 is provided with an inner ring middle rod 57 fixedly connected to the inner ring rotating rod 5 by screws, the bottom of the inner ring rotating rod 5 is rotatably connected to the base 55, and the top of the inner ring rotating rod 5 is rotatably connected to the top bearing 45.

[0054] Specifically, when the inner ring rotating rod 5 rotates, it drives the inner ring lower spiral blade 53 and the inner ring upper spiral blade 54 to rotate, which can further fully stir the material inside the device, and the inner ring rotating rod 5 rotates inside the base 55, which can support the inner ring rotating rod 5. Through the inner ring top rod 56, the inner ring middle rod 57 and the inner ring bottom rod 52, the stability of the inner ring lower spiral blade 53 and the inner ring upper spiral blade 54 can be enhanced.

[0055] In the above structure, the outer ring lower spiral leaf 43 is arranged clockwise, the outer ring upper spiral leaf 44 is arranged counterclockwise, the inner ring lower spiral leaf 53 is arranged counterclockwise, the inner ring upper spiral leaf 54 is arranged clockwise, the outer ring lower spiral leaf 43 is adapted to the inner ring lower spiral leaf 53, and the outer ring upper spiral leaf 44 is adapted to the inner ring upper spiral leaf 54.

[0056] Specifically, the outer ring rotating sleeve 4 rotates clockwise and the inner ring rotating rod 5 rotates counterclockwise, which can make the outer ring lower spiral leaves 43 and the inner ring lower spiral leaves 53 drive the gas or object to move upward, and at the same time, make the outer ring upper spiral leaves 44 and the inner ring upper spiral leaves 54 drive the gas or object to move downward, so that the internal material is fully stirred, and the outer ring rotating sleeve 4 and the inner ring rotating rod 5 rotate in opposite directions, which can improve the mixing degree of the internal gas and material, improve the extraction efficiency of the medicine, facilitate full extraction, and improve the utilization rate of the medicine.

[0057] Embodiment 1: The retractable stirring assembly 6 is used to further stir the device.

[0058] In further optimization of the above embodiment, the number of retractable stirring components 6 is set to be multiple, and the multiple retractable stirring components 6 are staggered on both sides of the inner ring rotating rod 5, and the outer ends of the retractable stirring components 6 extend to the inner sides of the outer ring lower spiral leaves 43 or the outer ring upper spiral leaves 44, so that the retractable stirring components 6 and the outer ring lower spiral leaves 43 or the outer ring upper spiral leaves 44 do not interfere with each other. Multiple retractable stirring components 6 are beneficial to further improve the stirring effect and further improve the internal extraction efficiency.

[0059] like Figure 7 and Figure 8 As shown, a limiting groove is provided near the inner end of the inner ring rotating rod 5 of the retractable stirring component 6, a slot is provided on the outer side of the limiting groove, a sliding block 62 is slidably connected inside the limiting groove, a push rod 63 extending to the outside of the slot is fixedly connected on the outer side of the sliding block 62, support rods 64 are hinged on both sides of the outer end of the push rod 63, stirring rods 65 are hinged on both sides of the outer end of the retractable stirring component 6, and the two stirring rods 65 are hinged to the support rods 64 on both sides, respectively.

[0060] In the above structure, the inner top and inner bottom walls of the limiting groove are provided with limiting slide grooves, the upper and lower sides of the sliding block 62 are fixedly connected with protrusions slidably connected to the limiting slide grooves, and the rear side of the sliding block 62 is fixedly connected with an elastic member 61 fixedly connected to the inner wall of the retractable stirring assembly 6.

[0061] Specifically, during the rotation of the inner ring rotating rod 5, the sliding block 62 slides outward under the action of centrifugal force, thereby pushing the push rod 63 to slide outward, and the protrusion slides inside the limiting slide groove to limit the push rod 63. The push rod 63 contacts the inner wall of the slot to prevent the medicine from entering the limiting groove. The push rod 63 pushes the support rod 64 to move outward, and the end of the support rod 64 is hinged to the stirring rod 65, thereby pushing the stirring rod 65 to expand. When the inner ring rotating rod 5 finishes rotating, the sliding block 62 is pulled to reset under the action of the elastic member 61. In the initial state of the sliding block 62, the two stirring rods 65 will maintain a certain angle with the retractable stirring assembly 6 to facilitate the expansion and movement, and the movement directions of the two stirring rods 65 are opposite.

[0062] In the above structure, an extraction chamber 31 and a feed chamber 32 are provided inside the reaction extraction kettle 3, an isolation plate 33 is fixedly connected between the extraction chamber 31 and the feed chamber 32, a plurality of evenly distributed feed holes are provided inside the isolation plate 33, and a dispersion chimney 38 is fixedly connected at the outlet of each feed hole, a one-way valve is installed inside each dispersion chimney 38, and a top plate 310 is fixedly connected to the top of the dispersion chimney 38.

[0063] Specifically, the supercritical fluid is input into the feed chamber 32 through the air inlet 34, and the feed chamber 32 enters the dispersion chimney 38 through the feed hole, and then enters the extraction chamber 31 through the dispersion chimney 38, so that the supercritical fluid can be dispersed and input to facilitate mixing with the internal medicine, and the top plate 310 can prevent the material on the top from entering the dispersion chimney 38, wherein the heights of the outer ring bottom rod 42 and the inner ring bottom rod 52 are both higher than the top of the dispersion chimney 38, so that there is no interference with the dispersion chimney 38 during stirring.

[0064] Furthermore, an air inlet 34 is provided on the side of the extraction chamber 31, and an outlet 37 is provided on the bottom side of the extraction chamber 31. One-way valves are installed inside the air inlet 34, the feed port 35 and the outlet 37, and the isolation plate 33 is inclined toward the outlet 37.

[0065] Specifically, the user can input the supercritical fluid into the device through the air inlet 34, place the medicine inside the extraction chamber 31 through the feed port 35, and output the extracted medicine through the discharge port 37. Multiple one-way valves can control the output and input of materials as needed, and the isolation plate 33 is tilted to fully output the internal materials.

[0066] In order to disperse and feed the materials in the first embodiment, the structure of the retractable stirring component 6 is further improved, and the second embodiment is proposed: Figure 11-14 As shown, the inner ring rotating rod 5 extends to the outside of the top of the outer ring rotating sleeve 4, and a feed pipe is fixedly connected to the middle of the top of the reaction extraction kettle 3, a pump group is arranged inside the feed pipe, the feed pipe is sealed and connected to the inner ring rotating rod 5, and the feed pipe is rotatably connected to the inner ring rotating rod 5, a feed channel extending to the bottom of the retractable stirring assembly 6 is opened inside the inner ring rotating rod 5, and the retractable stirring assembly 6 is connected to the feed channel;

[0067] A feed groove 601 is provided inside the retractable stirring component 6 near the inner ring rotating rod 5, and circulation grooves 603 are provided on both the upper and lower sides of the retractable stirring component 6. A distribution groove 602 is connected between the circulation groove 603 and the feed groove 601. A return spring 606 is fixedly connected to the end of the feed groove 601 away from the retractable stirring component 6, and a stopper 604 is slidably connected inside the feed groove 601. The end of the stopper 604 away from the inner ring rotating rod 5 is fixedly connected to a sliding rod 605 extending to the outside of the retractable stirring component 6, and the other end of the return spring 606 is fixedly connected to the stopper 604, and a limiting rod fixed to the inner wall of the feed groove 601 runs through the interior of the return spring 606;

[0068] The outlet of the circulation groove 603 is connected to a bulk material pipe 608, which is set as a hose. The first support rods 607 are hinged on both sides of the retractable stirring assembly 6, and a fixed plate 609 is fixedly connected between the first support rod 607 and the bulk material pipe 608. The end of the sliding rod 605 is fixedly connected to a cross bar 610, and both ends of the cross bar 610 are hinged to second support rods 611, and the other ends of the two second support rods 611 are hinged to the two first support rods 607 respectively.

[0069] Specifically, the user can input the material into the inner ring rotating rod 5 through the feed pipe, and the material enters the retractable stirring component 6 through the feed channel. When the material enters the feed trough 601, the motor 21 is started, and the motor 21 drives the inner ring rotating rod 5 to rotate, so that the stopper 604 slides outward under the action of centrifugal force, and at the same time, the material can squeeze the stopper 604, thereby pushing the stopper 604 and the sliding rod 605 to move outward, and the stopper 604 squeezes the return spring 606. When the stopper 604 moves to expose the distribution trough 602, the stopper 604 is against the limiting rod, thereby limiting the stopper 604. At this time, the material enters the circulation trough 603 through the distribution trough 602, and then is scattered into the interior of the reaction extraction kettle 3 through the dispersing pipe 608. When the sliding rod 6 05 slides outward, pushing the two second support rods 611 at the end to rotate upward or downward, the second support rod 611 drives the first support rod 607 at the end to rotate, and then the first support rod 607 drives the bulk tube 608 fixed on the side to bend upward or downward, so that the material can be dispersed, and the inner ring rotating rod 5 can disperse the material inside the device during the rotation process. The first support rod 607 and the bulk tube 608 can fully stir the material while stirring, thereby improving the reaction effect of the device. The ends of the bulk tube 608 are provided with one-way valves to prevent backflow. When the reaction is completed, the motor 21 and the pump group stop, and the block 604 is reset under the action of the reset spring 606, thereby driving the bulk tube 608 to reset.

[0070] The above description is only by way of illustration of certain exemplary embodiments of the present invention. It is undoubted that those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A supercritical extraction device for pharmaceutical use, comprising a substrate, characterized in that: The top of the base plate is detachably connected to a protective support shell by screws, the top of the protective support shell is fixedly connected to a reaction extraction kettle for extracting drugs, a mixing and stirring assembly is arranged inside the reaction extraction kettle, a control assembly for controlling the mixing and stirring assembly is arranged inside the protective support shell, and the mixing and stirring assembly includes an outer ring rotating sleeve, an inner ring rotating rod penetrating the outer ring rotating sleeve, and a retractable stirring assembly fixed on the outer side of the inner ring rotating rod; The control component includes a motor arranged inside the protective support shell, the top of the base plate is located inside the protective support shell and is fixedly connected to two symmetrically distributed vertical plates, the motor is installed on the outside of one of the vertical plates, the output end of the motor is fixedly connected to a power bevel gear through a coupling, the upper and lower sides of the power bevel gear are respectively meshed and connected with an outer ring driven gear and an inner ring driven gear, the outer ring driven gear is fixedly connected to the outside of the outer ring rotating sleeve, the inner ring driven gear is fixedly connected to the outside of the inner ring rotating rod, the outer ring rotating sleeve is rotatably connected to the inner ring rotating rod, a rotating bearing is connected between the outer ring rotating sleeve and the inner ring rotating rod, the outer side of the outer ring rotating sleeve is rotatably connected to a first fixed collar fixed on the protective support shell, the outer side of the inner ring rotating rod is rotatably connected to a second fixed collar fixed on the protective support shell, and the first fixed collar and the second fixed collar are both fixed on the inner side of the other vertical plate; The inner ring rotating rod extends to the outside of the top of the outer ring rotating sleeve, and a feed pipe is fixedly connected to the middle of the top of the reaction extraction kettle, a pump group is arranged inside the feed pipe, the feed pipe is sealed and connected to the inner ring rotating rod, and the feed pipe is rotatably connected to the inner ring rotating rod, and a feed channel extending to the bottom of the retractable stirring assembly is opened inside the inner ring rotating rod; A feed groove is provided inside the retractable stirring component near the inner ring rotating rod, and circulation grooves are provided on the upper and lower sides of the retractable stirring component. A distribution groove is connected between the circulation groove and the feed groove, and a return spring is fixedly connected to the end of the feed groove away from the retractable stirring component, and a stopper is slidably connected to the inside of the feed groove, and the end of the stopper away from the inner ring rotating rod is fixedly connected to the sliding rod extending to the outside of the retractable stirring component, and the other end of the return spring is fixedly connected to the stopper, and a limiting rod fixed to the inner wall of the feed groove is penetrated inside the return spring; The outlet of the circulation groove is connected to a bulk material pipe, the two sides of the retractable stirring assembly are hinged with a first support rod, a fixing plate is fixedly connected between the first support rod and the bulk material pipe, the end of the sliding rod is fixedly connected to a cross rod, the two ends of the cross rod are hinged with a second support rod, and the other ends of the two second support rods are respectively hinged to the two first support rods.

2. A pharmaceutical-specific supercritical extraction device according to claim 1, characterized in that: The outer side of the top of the outer ring rotating sleeve is fixedly connected with an outer ring bottom rod, the end of the outer ring bottom rod is fixedly connected with an outer ring lower spiral blade, the top of the outer ring lower spiral blade is fixedly connected with an outer ring upper spiral blade, a top bearing is arranged in the middle of the inner top wall of the reaction extraction kettle, a rotating block is rotatably connected inside the top bearing, and an outer ring top rod is fixedly connected between the rotating block and the outer ring upper spiral blade.

3. A pharmaceutical-specific supercritical extraction device according to claim 1, characterized in that: The outer side of the inner ring rotating rod is fixedly connected to the inner ring bottom rod by screws, the end of the inner ring bottom rod is fixedly connected to the inner ring lower spiral leaf by screws, the top of the inner ring lower spiral leaf is fixedly connected to the inner ring upper spiral leaf, the inner ring top rod is fixedly connected between the top of the inner ring upper spiral leaf and the inner ring rotating rod by screws, and an inner ring middle rod is provided at the connection between the inner ring lower spiral leaf and the inner ring upper spiral leaf, which is fixedly connected to the inner ring rotating rod by screws, the bottom of the inner ring rotating rod is rotatably connected to a base, and the top of the inner ring rotating rod is rotatably connected to the top bearing.

4. A pharmaceutical-specific supercritical extraction device according to claim 3, characterized in that: The lower spiral blades of the outer ring are arranged clockwise, the upper spiral blades of the outer ring are arranged counterclockwise, the lower spiral blades of the inner ring are arranged counterclockwise, and the upper spiral blades of the inner ring are arranged clockwise. The lower spiral blades of the outer ring are adapted to the lower spiral blades of the inner ring, and the upper spiral blades of the outer ring are adapted to the upper spiral blades of the inner ring.

5. The pharmaceutical-specific supercritical extraction equipment according to claim 3, characterized in that: The number of the retractable stirring components is set to be multiple, and the multiple retractable stirring components are staggered on both sides of the inner ring rotating rod, and the outer ends of the retractable stirring components extend to the inner sides of the lower spiral leaves of the outer ring or the upper spiral leaves of the outer ring, so that the retractable stirring components do not interfere with the lower spiral leaves of the outer ring or the upper spiral leaves of the outer ring.

6. A pharmaceutical-specific supercritical extraction device according to claim 1, characterized in that: The retractable stirring component has a limiting groove near the inner end of the inner ring rotating rod, and a slot is provided on the outer side of the limiting groove. A sliding block is slidably connected to the inside of the limiting groove, and a push rod extending to the outside of the slot is fixedly connected to the outer side of the sliding block. Support rods are hinged on both sides of the outer end of the push rod. Stirring rods are hinged on both sides of the outer end of the retractable stirring component, and the two stirring rods are hinged to the support rods on both sides respectively.

7. A pharmaceutical-specific supercritical extraction device according to claim 6, characterized in that: The inner top and inner bottom walls of the limiting groove are both provided with limiting slide grooves, the upper and lower sides of the sliding block are fixedly connected with protrusions slidably connected to the limiting slide grooves, and the rear side of the sliding block is fixedly connected with an elastic part fixedly connected to the inner wall of the retractable stirring assembly.

8. The pharmaceutical-specific supercritical extraction equipment according to claim 1, characterized in that: An extraction chamber and a feed chamber are provided inside the reaction extraction kettle, an isolation plate is fixedly connected between the extraction chamber and the feed chamber, a plurality of evenly distributed feed holes are provided inside the isolation plate, and a dispersion chimney is fixedly connected at the outlet of each of the feed holes, a one-way valve is installed inside each of the dispersion chimneys, and a top plate is fixedly connected to the top of the dispersion chimney.

9. A pharmaceutical-specific supercritical extraction device according to claim 8, characterized in that: An air inlet is arranged on the side of the extraction chamber, and an outlet is arranged on one side of the bottom of the extraction chamber. One-way valves are installed inside the air inlet, the feed inlet and the outlet, and the isolation plate is inclined toward the outlet.

10. The pharmaceutical-specific supercritical extraction equipment according to claim 1, characterized in that: The bulk material pipe is configured as a hose.

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