A cosmetic composition with soothing and repairing effects and its application

Abstract

The present invention provides a cosmetic composition with soothing and repairing effects and its application, comprising the following components in parts by weight: 1.5 to 6 parts of mussel extract, 0.1 to 50 parts of Mirabilis jalapa extract, 0.1 to 40 parts of healing velvet flower extract and 0.1 to 10 parts of dipotassium glycyrrhizinate. The cosmetic composition with soothing and repairing effects of the present invention combines mussel extract, Mirabilis jalapa extract, healing velvet flower extract and dipotassium glycyrrhizinate, repairs the skin barrier function through mussel extract, Mirabilis jalapa extract inhibits the expression of TRPV1, a receptor related to skin sensory nerves, and healing velvet flower extract and dipotassium glycyrrhizinate inhibit the three major pathways of inflammatory factors such as IL-1α, PEG2 and leukotriene B4, synergistically improving the soothing and repairing effects of the cosmetic composition, which is safe, gentle and efficient. The soothing and repairing composition of the present invention is added to cosmetics, which can instantly soothe skin allergic reactions and repair the skin barrier, so that the skin can be restored to a healthy state.

Description

Technical Field

[0001] The present invention relates to the field of cosmetics, and in particular to a cosmetic composition with soothing and repairing effects and application thereof. Background Art

[0002] With the rapid development of diversified cosmetics, consumers are using more and more types of cosmetics and using them more frequently, and the probability of skin contact with irritants is increasing simultaneously. As a result, more and more consumers are experiencing thinning of their stratum corneum and damaged skin barrier, making the number of people with sensitive skin increase day by day. Domestic and foreign markets are also paying more and more attention to products with anti-allergic and repair effects.

[0003] At present, the formula design of soothing and repairing products on the market often meets the needs of sensitive skin by not reducing the amount of preservatives added, not adding fragrances, and adding soothing and repairing ingredients. However, the safety and soothing and repairing effects of existing cosmetics with soothing and repairing effects need to be improved. Summary of the invention

[0004] The purpose of the present invention is to overcome the shortcomings of the prior art and provide a cosmetic composition with soothing and repairing effects and its application.

[0005] To achieve the above-mentioned purpose, the technical solution adopted by the present invention is: a cosmetic composition with soothing and repairing effects, the cosmetic composition comprising the following components in parts by weight: 1.5 to 6 parts of mussel extract, 0.1 to 50 parts of Mirabilis jalapa extract, 0.1 to 40 parts of healing velvet flower extract and 0.1 to 10 parts of dipotassium glycyrrhizinate.

[0006] The above-mentioned cosmetic composition with soothing and repairing effects repairs the skin barrier function through mussel extract, and Mirabilis jalapa extract inhibits the expression of skin sensory nerve-related receptor TRPV1. The healing velvet flower extract and dipotassium glycyrrhizinate inhibit the three major pathways of inflammatory factors such as IL-1α, PEG2 and leukotriene B4, thereby achieving the soothing and repairing effects, which is safe, gentle and highly effective.

[0007] Preferably, in the cosmetic composition, the weight ratio of mussel extract, Mirabilis jalapa extract, velvetia odorata extract and dipotassium glycyrrhizinate is mussel extract: Mirabilis jalapa extract: velvetia odorata extract: dipotassium glycyrrhizinate = (4-6): (10-50): (0.1-40): (1-10).

[0008] The inventors studied the ratio of the content of the components in the above-mentioned composition and found that the ratio of the content of the components has a significant effect on the soothing and repairing effect of the cosmetic composition, and when the weight ratio of the mussel extract, the Mirabilis jalapa extract, the healing velvet flower extract and the dipotassium glycyrrhizinate is (4-6): (10-50): (0.1-40): (1-10), it has a better soothing and repairing effect.

[0009] Preferably, in the cosmetic composition, the weight ratio of mussel extract, Mirabilis jalapa extract, Echeveria odorata flower extract and dipotassium glycyrrhizinate is mussel extract: Mirabilis jalapa extract: Echeveria odorata flower extract: dipotassium glycyrrhizinate = (4-6): (10-50): (6-40): (4-10).

[0010] The present invention also provides use of any of the above-mentioned cosmetic compositions in preparing cosmetics.

[0011] The soothing and repairing composition is added to cosmetics to instantly soothe skin allergic reactions and repair the skin barrier, restoring the skin to a healthy state. It is safe, gentle, highly effective and has good repairing effects.

[0012] The present invention also provides a cosmetic comprising any one of the above-mentioned cosmetic compositions.

[0013] The present invention also provides a cosmetic, which comprises the following components in percentage by weight: 0.15% to 0.6% of mussel extract, 0.01% to 5% of Mirabilis jalapa extract, 0.01% to 4% of velvetleaf flower extract, 0.01% to 1% of dipotassium glycyrrhizinate, 10% to 15% of moisturizer, 0.8% to 1.2% of emulsifier, 0.15% to 0.25% of thickener, 0.15% to 0.25% of preservative and the balance of water.

[0014] The above-mentioned cosmetics can instantly relieve skin allergic reactions and repair the skin barrier, restoring the skin to a healthy state. The above-mentioned cosmetics are safe, gentle, highly effective and have good repair effects. In cosmetics, mussel extract is used to repair the skin barrier function, Mirabilis jalapa extract inhibits the expression of TRPV1 receptors related to skin sensory nerves, and the healing velvet flower extract and dipotassium glycyrrhizinate inhibit the three major pathways of inflammatory factors such as IL-1α, PEG2 and leukotriene B4, achieving the effect of soothing and repairing, which is safe, gentle and highly effective.

[0015] Preferably, the cosmetic comprises the following components in percentage by weight: 0.4% to 0.6% of mussel extract, 1% to 5% of Mirabilis jalapa extract, 0.1% to 4% of velvetleaf flower extract, and 0.1% to 1% of dipotassium glycyrrhizinate.

[0016] Preferably, the cosmetic comprises the following components in percentage by weight: 0.4% to 0.6% of mussel extract, 1% to 5% of Mirabilis jalapa extract, 0.6% to 4% of velvetleaf flower extract, and 0.4% to 1% of dipotassium glycyrrhizinate.

[0017] Preferably, the thickener is carbomer, the preservative is sodium benzoate, the emulsifier is PEG-20 glyceryl triisostearate, the moisturizer includes 2.50% to 3.50% glycerol, 0.80% to 1.20% betaine, 3.50% to 4.50% squalane, 2.50% to 3.50% undecane (and) tridecane and 0.80% to 1.20% cetyl alcohol, and the mass ratio of undecane to tridecane is 7:3.

[0018] The present invention also provides a method for preparing the above-mentioned cosmetic, which comprises the following steps:

[0019] (1) stirring and dissolving the raw materials of phase A according to the weight ratio, heating to 80-85° C. and then keeping the temperature for 10-20 minutes; the raw materials of phase A include deionized water, glycerol, betaine and carbomer;

[0020] (2) stirring and dissolving the raw materials of phase B according to the weight ratio, heating to 80-85° C. and then keeping the temperature for 10-20 minutes; the raw materials of phase B include squalane, undecane (and) tridecane, cetyl alcohol and PEG-20 glyceryl isostearate;

[0021] (3) Mix phase B and phase A according to the weight ratio and mix them evenly;

[0022] (4) cooling the mixture to below 45° C., adding the raw materials of phase C according to the weight ratio, and stirring evenly; the raw materials of phase C include mussel extract, Mirabilis jalapa extract, velvetleaf flower extract, dipotassium glycyrrhizate, and sodium benzoate; and continuing stirring and cooling the mixture to below 30° C. to obtain the cosmetic.

[0023] The beneficial effects of the present invention are as follows: the present invention provides a cosmetic composition with soothing and repairing effects and its application. The cosmetic composition with soothing and repairing effects of the present invention combines mussel extract, Mirabilis jalapa extract, velvetia odorata extract, and dipotassium glycyrrhizinate. The mussel extract repairs the skin barrier function, the Mirabilis jalapa extract inhibits the expression of TRPV1, a receptor related to the skin sensory nerve, and the velvetia odorata extract and dipotassium glycyrrhizinate inhibit the three major pathways of inflammatory factors such as IL-1α, PEG2, and leukotriene B4, thereby synergistically improving the soothing and repairing effects of the cosmetic composition, which is safe, mild, and highly effective. The soothing and repairing composition of the present invention is added to cosmetics to instantly soothe skin allergic reactions and repair the skin barrier, thereby restoring the skin to a healthy state. DETAILED DESCRIPTION

[0024] In order to better illustrate the purpose, technical solutions and advantages of the present invention, the present invention will be further described below in conjunction with specific embodiments.

[0025] The invention provides a cosmetic composition with soothing and repairing effects, comprising the following components in parts by weight: 1.5 to 6 parts of mussel extract, 0.1 to 50 parts of Mirabilis jalapa extract, 0.1 to 40 parts of velvetleaf flower extract and 0.1 to 10 parts of dipotassium glycyrrhizinate.

[0026] The present invention also provides a cosmetic, comprising the following components in percentage by weight: 0.15% to 0.6% of mussel extract, 0.01% to 5% of Mirabilis jalapa extract, 0.01% to 4% of velvetia jalapa extract, 0.01% to 1% of dipotassium glycyrrhizinate, 10% to 15% of moisturizer, 0.8% to 1.2% of emulsifier, 0.15% to 0.25% of thickener, 0.15% to 0.25% of preservative and the balance of water; the thickener is carbomer, the preservative is sodium benzoate, the emulsifier is PEG-20 glyceryl triisostearate, the moisturizer comprises 2.50% to 3.50% of glycerol, 0.80% to 1.20% of betaine, 3.50% to 4.50% of squalane, 2.50% to 3.50% of undecane (and) tridecane and 0.80% to 1.20% of cetyl alcohol.

[0027] The cosmetic formulas of Examples 1 to 5 and Comparative Examples 1 to 3 are shown in Table 1.

[0028] Table 1

[0029]

[0030] The method for preparing the cosmetics of the embodiment comprises the following steps:

[0031] (1) adding the raw materials of phase A into a water phase pot according to the weight ratio, stirring and dissolving at a speed of 180 r / min, heating to 80-85° C. and then keeping warm for 15 minutes; the raw materials of phase A include deionized water, glycerol, betaine, and carbomer;

[0032] (2) adding the raw materials of phase B into the oil phase pot according to the weight ratio, stirring and dissolving at a speed of 180 r / min, heating to 80-85° C. and then keeping warm for 15 minutes; the raw materials of phase B include squalane, undecane (and) tridecane, cetyl alcohol, and PEG-20 glyceryl isostearate;

[0033] (3) Add phase B to phase A according to the weight ratio, stir at a speed of 180 r / min, and then homogenize at a speed of 3000 r / min for 5 min;

[0034] (4) cooling to below 45° C., adding phase C raw materials according to weight ratio, and stirring evenly at a speed of 200 r / min; the phase C raw materials include: mussel extract, Mirabilis jalapa extract, velvetleaf flower extract, dipotassium glycyrrhizate and sodium benzoate; continuing stirring and cooling to below 30° C., and discharging to obtain a cosmetic emulsion.

[0035] Performance Testing

[0036] 1. Security testing

[0037] Human skin closed patch test, trial method is based on: "Technical Specifications for Safety of Cosmetics" (2015 edition).

[0038] Test method: Select a suitable patch tester, and select at least 30 qualified volunteers to participate in the test using the closed patch test method. Add the test substance to the square chamber of the patch tester, and the control hole is a blank control. Apply the patch tester with the test substance to the inner side of the subject's forearm, and press it lightly with the palm of your hand to evenly apply it to the skin for 24 hours. Observe the skin reaction according to the standards in Table 2 30 minutes (after the indentation disappears), 24 hours and 48 hours after removing the test substance patch tester, and record the observation results.

[0039] Principles for determining results: If more than 5 out of 30 subjects have grade 1 adverse skin reactions, or more than 2 have grade 2 adverse skin reactions, or any grade 3 or higher adverse skin reaction occurs, the test substance is judged to have adverse skin reactions in humans.

[0040] Table 2 Skin reaction grading standards for skin occlusive patch test

[0041]

[0042] Table 3 Skin occlusive patch test results

[0043]

[0044] It can be seen from Table 3 that the cosmetics of the examples are non-irritating to human skin and have good safety in use.

[0045] 2. Soothing and repairing effect test

[0046] Test population: Female volunteers with sensitive facial skin, specifically showing one or more skin problems such as redness, burning, dryness, peeling, itching and stinging. A total of 90 qualified internal and external volunteers (randomly divided into 9 groups, 10 people in each group), aged 18-45 years old, were screened. The trial design was randomized, double-blind, and historically controlled.

[0047] Product usage requirements: Volunteers use the composition sample or placebo control on the entire face after cleansing every morning and evening for 28 consecutive days, and conduct a questionnaire survey on the effect of use and a transepidermal water loss test at specific time points.

[0048] (1) Consumer use test

[0049] Test method: Volunteers completed a questionnaire survey 28 days after using the product.

[0050] Effect judgment criteria:

[0051] Cured: The product is obviously effective and the skin allergy condition has been completely improved

[0052] Effective: The product is effective and skin allergies are alleviated

[0053] Ineffective: The product is ineffective, the skin allergy condition has not been alleviated, or even worsened

[0054] How to use the product: Apply evenly on the face.

[0055] The test results are shown in Table 4.

[0056] Table 4 Anti-allergic repair effect of cosmetics

[0057]

[0058]

[0059] As shown in Table 4, the combination of mussel extract, Mirabilis jalapa extract, velvetleaf flower extract, and dipotassium glycyrrhizinate synergistically improves the soothing and repairing effect of the cosmetic composition.

[0060] (2) Transepidermal water loss test

[0061] Test instrument: VapoMeter (Delfin, Finland)

[0062] Test environment: temperature 21℃±1℃, relative humidity 40%~60%

[0063] Test method: Volunteers were tested before using the product, on the 14th day and the 28th day after using the product. Each time, they cleaned their face with a unified amino acid cleansing mousse, and then waited for 20 minutes in a test environment that met the requirements before conducting a transepidermal water loss test. The test area was the cheek area.

[0064] Test results:

[0065]

[0066]

[0067] As can be seen from Table 5, the cosmetic emulsion of the present invention can effectively reduce the water loss of the skin and effectively repair the barrier function of the skin.

[0068] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention rather than to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solution of the present invention can be modified or replaced by equivalents without departing from the essence and scope of the technical solution of the present invention.

Claims

1. A cosmetic composition with soothing and repairing effects, characterized in that: The cosmetic composition consists of the following components in parts by weight: 4 to 6 parts of mussel extract, 10 to 50 parts of Mirabilis jalapa extract, 6 to 40 parts of velvetleaf flower extract and 4 to 10 parts of dipotassium glycyrrhizinate.

2. A cosmetic, characterized in that: The cosmetic comprises the following components in percentage by weight: 0.4% to 0.6% of mussel extract, 1% to 5% of Mirabilis jalapa extract, 0.6% to 4% of velvetleaf flower extract, 0.4% to 1% of dipotassium glycyrrhizinate, 10% to 15% of moisturizer, 0.8% to 1.2% of emulsifier, 0.15% to 0.25% of thickener, 0.15% to 0.25% of preservative and the balance of water.

3. The cosmetic according to claim 2, characterized in that: The thickener is carbomer, the preservative is sodium benzoate, the emulsifier is PEG-20 glyceryl triisostearate, the moisturizer includes 2.50%-3.50% glycerol, 0.80%-1.20% betaine, 3.50%-4.50% squalane, 2.50%-3.50% undecane and tridecane, and 0.80%-1.20% cetyl alcohol, and the mass ratio of undecane to tridecane is 7:

3.

4. The method for preparing the cosmetic according to claim 3, characterized in that: The method comprises the following steps: (1) Stir and dissolve the raw materials of phase A according to the weight ratio, heat to 80-85° C. and keep warm for 10-20 minutes; the raw materials of phase A include deionized water, glycerol, betaine and carbomer; (2) stirring and dissolving the raw materials of phase B according to the weight ratio, heating to 80-85° C. and then keeping the temperature for 10-20 minutes; the raw materials of phase B include squalane, undecane and tridecane, cetyl alcohol and PEG-20 glyceryl isostearate; (3) Mix phase B and phase A according to the weight ratio and mix them evenly; (4) Cooling the mixture to below 45°C, adding the raw materials of phase C according to the weight ratio, and stirring evenly; the raw materials of phase C include mussel extract, Mirabilis jalapa extract, velvetleaf flower extract, dipotassium glycyrrhizate and sodium benzoate; continuing to stir and cool the mixture to below 30°C to obtain the cosmetic.

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