Intracranial probe and intracranial detection components

Abstract

This application specifically relates to an intracranial probe and an intracranial detection assembly. The intracranial probe includes: a housing with a window, an internal chamber communicating with the window, and a stepped structure forming the side wall of the chamber; and a sensor assembly disposed within the chamber, comprising a pressure sensor and a temperature sensor. The pressure sensor is placed on the stepped surface facing the window, while the temperature sensor is disposed within a sealed cavity inside the housing that isolates intracranial fluid. The side wall of the stepped structure forms a channel between the pressure sensor and the temperature sensor, communicating with a standard atmospheric pressure. This application's intracranial probe proposes that the pressure sensor be positioned facing the window via the stepped surface to achieve frontal sensing of intracranial pressure, while the side of the stepped structure facing away from the pressure sensor forms a channel communicating with a standard atmospheric pressure. The zero-point of the sensor assembly is calibrated using the standard atmospheric pressure, reducing the phenomenon of zero-point drift in the sensor assembly.

Description

Technical Field

[0001] This application relates to the field of medical device technology, specifically to an intracranial probe and an intracranial detection component. Background Technology

[0002] This section provides only background information relevant to this disclosure and is not necessarily prior art.

[0003] Intracranial pressure and intracranial temperature are important parameters in craniotomy. Intracranial pressure (ICP) is an important indicator reflecting the physiological state of the central nervous system (CNS) and intracranial hemodynamics. Intracranial monitoring includes invasive monitoring, which mainly includes: external ventricular drainage (EVD) via catheter, lumbar puncture (LP) and lumbar drainage (LD), epidural and subdural pressure sensors, implantable microsensors, intraparenchymal probes, telemetry sensors, etc.

[0004] Existing invasive intracranial monitoring methods have the following shortcomings:

[0005] 1) Oversized intracranial probe: The intracranial probe needs to penetrate deep into the patient's brain tissue to perform corresponding data measurements. If the intracranial probe is too large, the required incision will be too large, which can easily cause secondary damage.

[0006] 2) The intracranial probe contains a temperature sensor and a pressure sensor. The intracranial probe is inserted into the patient's brain and pressure and temperature are measured through the pressure sensor and temperature sensor. Improper installation of the pressure sensor and temperature sensor may cause zero drift due to measurement error.

[0007] 3) During craniocerebral surgery, the intracranial probe needs to be placed inside the brain for a long time. The temperature sensor is prone to drift of the zero point of the temperature measurement due to continuous temperature measurement for a long time, resulting in inaccurate measurement. The pressure sensor surface is prone to deformation of the pressure film due to long-term pressure, which can also cause the zero point of the pressure to drift, resulting in increased measurement error. Summary of the Invention

[0008] The purpose of this application is to at least solve the technical problem that an unreasonable internal structural layout of an intracranial probe leads to an increase in the size of the intracranial probe and affects its sensing effect. This purpose is achieved through the following technical solution:

[0009] The first aspect of this application provides an intracranial probe, comprising: a housing having a window, an internal cavity communicating with the window, and a stepped structure formed on the side wall of the cavity; and a sensor assembly disposed in the cavity, the sensor assembly including a pressure sensor and a temperature sensor, the pressure sensor being placed on the platform of the stepped structure and facing the window, the temperature sensor being disposed in a sealed cavity inside the housing that isolates intracranial fluid, and the side wall of the stepped structure forming a channel located between the pressure sensor and the temperature sensor and communicating with a standard air pressure.

[0010] Those skilled in the art will understand that the intracranial probe of this application integrates a pressure sensor and a temperature sensor inside the intracranial probe. The pressure sensor and temperature sensor are coordinated through a stepped structure, so that the pressure sensor can face the window through the platform of the stepped structure to achieve the purpose of frontal sensing of intracranial pressure. The temperature sensor is placed inside the shell to isolate the intracranial fluid in a sealed cavity, so as to prevent the temperature sensor from directly contacting the intracranial fluid. Furthermore, the side wall of the stepped structure forms a channel between the pressure sensor and the temperature sensor to communicate with the standard air pressure. The sensing zero point of the sensor assembly is corrected by the standard air pressure, reducing the phenomenon of sensing zero point drift of the sensor assembly during use.

[0011] In some embodiments, the intracranial probe further includes a flexible support with its edge flush with the table surface and in contact with a pressure sensor, a temperature sensor disposed on the side of the flexible support facing away from the window, and the middle portion of the flexible support extending into the interior of the receiving chamber and isolating the pressure sensor from the temperature sensor.

[0012] In some embodiments, a channel is formed between the middle of the flexible stent and the back of the pressure sensor, the channel forming an airway connected to standard air pressure, and the airway and intracranial fluid creating a pressure difference on both sides of the pressure sensor.

[0013] In some embodiments, the proximal end of the housing is provided with a through hole communicating with the airway. The through hole and the airway form a closed channel within the housing. The closed channel is configured to cooperate with an intracranial pressure catheter and communicate with standard air pressure through the intracranial pressure catheter.

[0014] In some embodiments, the wires of the temperature sensor and / or the pressure sensor extend into the channel and through the intracranial pressure catheter to the outside of the intracranial probe.

[0015] In some embodiments, the pressure sensor is configured as a plate-like structure, with the edges of the plate-like structure laid flat on the table surface via the edges of a flexible support.

[0016] In some embodiments, the temperature sensor is configured as a columnar structure, and a flexible cylindrical support frame that cooperates with the columnar structure is provided at the bottom of the receiving chamber.

[0017] In some embodiments, the intracranial probe further includes a sensing coating for sensing intracranial pressure and temperature, the sensing coating covering the window and sealing the pressure sensor and temperature sensor.

[0018] The second aspect of this application provides an intracranial detection assembly, which includes: an intracranial probe, the intracranial probe being the intracranial probe according to the first aspect of this application; and a catheter assembly, including a drainage tube and an intracranial pressure catheter, wherein the intracranial probe is disposed inside the drainage tube, the drainage tube is provided with a drainage port corresponding to the window of the intracranial probe, and the intracranial pressure catheter is disposed inside the drainage tube and communicates with the through hole of the intracranial probe.

[0019] In some embodiments, an intracranial probe is disposed at the distal end of the drainage tube, a drainage port is disposed on the distal tube wall, and a drainage hole communicating with a window is also provided on the middle section side wall of the drainage tube. Attached Figure Description

[0020] Various other advantages and benefits will become apparent to those skilled in the art upon reading the following detailed description of preferred embodiments. The accompanying drawings are for illustrative purposes only and are not intended to limit the scope of this application. Furthermore, the same reference numerals denote the same parts throughout the drawings. In the drawings:

[0021] Figure 1 This is a schematic diagram of the assembly structure of an intracranial detection component according to an embodiment of this application;

[0022] Figure 2 for Figure 1 A schematic diagram of the disassembled structure of the intracranial detection component shown;

[0023] Figure 3 for Figure 1 A schematic diagram showing a partial structural breakdown of the intracranial detection component;

[0024] Figure 4 for Figure 3 A schematic diagram of the intracranial probe in the intracranial detection assembly shown;

[0025] Figure 5 for Figure 4 The diagram shows the structural schematic of the shell in the intracranial probe.

[0026] The reference numerals in the attached figures are as follows:

[0027] 100. Intracranial detection components;

[0028] 10. Intracranial probe; 11. Housing; 111. Window; 112. Reception chamber; 113. Stepped structure; 114. Through hole; 12. Pressure sensor; 121. Circuit board; 122. Pressure sensing diaphragm; 123. Pressure sensing wire; 13. Temperature sensor; 131. Temperature sensing wire; 14. Flexible support; 15. Flexible cylindrical support frame;

[0029] 20. Drainage tube; 21. Distal end; 211. Drainage port; 22. Middle section; 221. Drainage hole; 23. Proximal end; 24. Drainage valve;

[0030] 30. Intracranial pressure catheter;

[0031] 40. Terminal. Detailed Implementation

[0032] Exemplary embodiments of the present disclosure will now be described in more detail with reference to the accompanying drawings. While exemplary embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure can be implemented in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided to enable a more thorough understanding of the present disclosure and to fully convey the scope of the disclosure to those skilled in the art. It should be noted that the detection of intracranial signals using an intracranial probe in this application is merely a preferred embodiment and does not limit the application scope of the intracranial probe. For example, the intracranial probe of this application can also be applied to other human tissues such as blood vessels, and such adjustments do not deviate from the application scope of the intracranial probe of this application. Furthermore, pressure sensors and temperature sensors are merely preferred embodiments of the sensor components in the embodiments of this application and do not limit the type of sensor components. Sensor components can also be various sensing elements capable of sensing changes in the external boundary environment (such as pressure, temperature, pH value, etc.) and generating electrical signal outputs, which will not be described in detail here.

[0033] It should be understood that the terminology used herein is for the purpose of describing particular exemplary embodiments only and is not intended to be limiting. Unless the context clearly indicates otherwise, the singular forms “a,” “an,” and “described” as used herein may also mean including the plural forms. The terms “comprising,” “including,” and “having” are inclusive and therefore indicate the presence of the stated features, elements, and / or components, but do not exclude the presence or addition of one or more other features, elements, components, and / or combinations thereof.

[0034] Although terms such as "first," "second," etc., may be used in this document to describe multiple elements, components, regions, layers, and / or segments, these elements, components, regions, layers, and / or segments should not be limited by these terms. These terms may be used only to distinguish one element, component, region, layer, or segment from another. Unless the context clearly indicates otherwise, terms such as "first," "second," and other numerical terms used herein do not imply order or sequence. Furthermore, in the description of this application, unless otherwise expressly specified and limited, the terms "set up" and "connected" should be interpreted broadly; for example, they may refer to a fixed connection, a detachable connection, or an integral connection; they may refer to a direct connection or an indirect connection via an intermediate medium. Those skilled in the art will understand the specific meaning of the above terms in this application based on the specific circumstances.

[0035] For ease of description, spatial relative terms may be used in the text to describe the relationship of one element or feature relative to another element or feature, as shown in the figure. These relative terms include, for example, "inside," "sidewall," "facing," "back to," "flush," "middle," "back," "face," "proximal," "external," "edge," "end," "length," "far end," "middle section," etc. Such spatial relative terms are intended to include different orientations of the mechanism in use or operation, in addition to those depicted in the figure. For example, if the mechanism in the figure is flipped, an element described as "below other elements or features" or "below other elements or features" would subsequently be oriented as "above other elements or features" or "above other elements or features." Therefore, the example term "below" can include both upper and lower orientations. The mechanism may be otherwise oriented (rotated 90 degrees or in other directions), and the spatial relative descriptors used in the text will be interpreted accordingly.

[0036] Intracranial pressure (ICP) refers to the pressure exerted by the contents of the skull on the walls of the cranial cavity. It is composed of two factors: hydrostatic pressure and pressure from changes in vascular tension. A relatively stable ICP is maintained through physiological regulation. Under normal physiological conditions, the total volume of the three main intracranial contents—brain tissue, cerebrospinal fluid, and blood—is relatively constant. Therefore, the regulation of ICP within the normal range becomes a balance between cerebral blood flow and cerebrospinal fluid; an increase in one volume requires a decrease in the other to compensate. When an increase in intracranial contents cannot be compensated for by a decrease in other components, ICP increases. There are four common causes of increased ICP: increased brain tissue, increased cerebrospinal fluid, increased intracranial blood volume, and the presence of new intracranial components.

[0037] Increased intracranial pressure (ICP) has three main symptoms: headache, vomiting, and papilledema. Prolonged elevated ICP can lead to a series of physiological dysfunctions and pathological changes. When ICP reaches a certain level, it can severely affect cerebral blood flow, causing cerebral ischemia and hypoxia, resulting in cerebral edema, further exacerbating ICP, and causing brain tissue displacement and herniation. It can also compress or damage the hypothalamus, causing autonomic nervous system dysfunction, leading to acute gastrointestinal ulcers, perforation, and hemorrhage. Severe ICP often results in complications such as pulmonary edema. If brain tissue deformation affects cerebral blood vessels, an ICP exceeding 3.33 kPa (25 mmHg) can cause serious consequences, even brain death. Intracranial pressure and intracranial temperature are important parameters in craniotomy. Intracranial pressure (ICP) is a crucial indicator reflecting the physiological state of the central nervous system (CNS) and intracranial hemodynamics. ICP monitoring is highly valuable in the treatment of critically ill neurological patients and is widely used in conditions such as traumatic brain injury, intracranial hemorrhage, brain tumors, intracranial infections, and hydrocephalus. Intracranial monitoring includes both invasive and non-invasive methods. Although non-invasive monitoring has seen significant development in recent years, its accuracy remains relatively low. Invasive intracranial pressure monitoring mainly includes: external ventricular drainage (EVD), lumbar puncture (LP) and lumbar drainage (LD), epidural and subdural pressure sensors, implantable microsensors, intraparenchymal probes, and telemetry sensors.

[0038] Invasive intracranial monitoring on the market has the following shortcomings:

[0039] 1) Oversized intracranial probe: The intracranial probe needs to penetrate deep into the patient's brain tissue to perform corresponding data measurements. If the intracranial probe is too large, the required incision will be too large, which can easily cause secondary damage.

[0040] 2) The intracranial probe contains a temperature sensor and a pressure sensor. The intracranial probe is inserted into the patient's brain and pressure and temperature are measured through the pressure sensor and temperature sensor. Improper installation of the pressure sensor and temperature sensor may cause zero drift due to measurement error.

[0041] 3) During craniocerebral surgery, the intracranial probe needs to be placed inside the brain for a long time. The temperature sensor is prone to drift of the zero point of the temperature measurement due to continuous temperature measurement for a long time, resulting in inaccurate measurement. The pressure sensor surface is prone to deformation of the pressure film due to long-term pressure, which can also cause the zero point of the pressure to drift, resulting in increased measurement error.

[0042] This application addresses the issue of poor detection performance caused by unreasonable structural design of intracranial probes. It proposes a step structure on the inner wall of the intracranial probe housing, which works in conjunction with pressure and temperature sensors to meet the sensing position requirements of the pressure and temperature sensors. This improves the detection reliability and stability of the intracranial probe and is conducive to the development of intracranial probes towards miniaturization and integration.

[0043] like Figures 1 to 5 As shown, the first aspect of this application provides an intracranial probe 10, including a housing 11 and a sensor assembly (described in detail below). The housing 11 is provided with a window 111, and the interior of the housing 11 is provided with a receiving chamber 112 communicating with the window 111. The sidewall of the receiving chamber 112 forms a stepped structure 113. The sensor assembly is disposed in the receiving chamber 112 and includes a pressure sensor 12 and a temperature sensor 13. The pressure sensor 12 is placed on the platform of the stepped structure 113 and faces the window 111. The temperature sensor 13 is disposed in a sealed cavity inside the housing 11 that isolates intracranial fluid. The sidewall of the stepped structure 113 forms a channel (the location of the receiving chamber 112) located between the pressure sensor 12 and the temperature sensor 13 and communicating with standard air pressure.

[0044] In this embodiment, the intracranial probe 10 of this application integrates a pressure sensor 12 and a temperature sensor 13 inside the intracranial probe 10. The pressure sensor 12 and temperature sensor 13 are cooperated with the step structure 113, so that the pressure sensor 12 can face the window 111 through the platform of the step structure 113 to achieve the purpose of frontal sensing of intracranial pressure. The step structure 113 forms a sealed cavity inside the shell 11 that isolates intracranial fluid and accommodates the temperature sensor 13. The sealed cavity can be formed in the step structure 113 or in the inner wall of the shell 11, so as to prevent the temperature sensor 13 from directly contacting the intracranial fluid. It also facilitates the miniaturization of the intracranial probe 10.

[0045] Specifically, as those skilled in the art will understand, when the intracranial probe 10 is inserted into the cranium, a portion of the intracranial fluid is located around the housing 11 of the intracranial probe 10. The intracranial probe 10 detects intracranial pressure by detecting the pressure of the fluid around the intracranial probe 10. Since the housing 11 is provided with a window 111, most of the intracranial fluid around the housing 11 flows towards the receiving chamber 112 of the housing 11 in the direction facing the window 111. In order to enable the pressure sensor to accurately detect the pressure of the intracranial fluid flowing towards the window 111, the embodiments of this application propose to provide a stepped structure 113 on the side wall of the receiving chamber 112, and to set the pressure sensor 12 on the platform of the stepped structure 113 so that the pressure sensor 12 faces the window 111, thereby achieving the purpose of frontal sensing of intracranial fluid pressure and improving the sensing accuracy of the pressure sensor 12.

[0046] Furthermore, the space between the two sidewalls of the stepped structure 113 not only forms an installation space for the temperature sensor 13, but also creates a channel connecting the pressure sensor 12 and the temperature sensor 13 to a standard atmospheric pressure. The standard atmospheric pressure includes the external atmosphere or a standard atmospheric pressure device. This standard atmospheric pressure is used to correct the zero point of the sensor assembly, reducing zero-point drift. Specifically, during craniocerebral surgery, the intracranial probe 10 needs to be placed inside the brain for an extended period. Prolonged continuous temperature measurement by the temperature sensor 13 can easily cause zero-point drift, leading to distorted measurement results. Similarly, the surface of the pressure sensor 12, subjected to prolonged intracranial pressure, is prone to deformation of its pressure diaphragm, causing zero-point drift and resulting in distorted measurement results. The embodiments of this application propose to calibrate the temperature measurement zero point of the temperature sensor 13 and the pressure measurement zero point of the pressure sensor 12 by using standard air pressure, so that the temperature measurement zero point of the temperature sensor 13 is always consistent with the standard air pressure temperature, and the pressure measurement zero point of the pressure sensor 12 is consistent with the standard air pressure temperature, thereby improving the measurement reliability and accuracy of the pressure sensor 12 and the temperature sensor 13.

[0047] It should be noted that the embodiments of this application do not limit the specific structure and positional relationship of the housing 11, pressure sensor 12, and temperature sensor 13 of the intracranial probe 10. This is because the application focuses on achieving a reasonable assembly position of the pressure sensor 12 and temperature sensor 13 through the stepped structure 113, thereby reducing measurement distortion caused by unreasonable assembly positions of the pressure sensor 12 and temperature sensor 13. Furthermore, the stepped structure 113 connects to a standard air pressure to calibrate the zero point of the pressure sensor 12 and the temperature sensor 13. The measurement of the zero temperature point involves various arrangements of the housing 11, pressure sensor 12, and temperature sensor 13 of the intracranial probe 10, including their specific structures and positional relationships. For example, the housing 11 can be a rectangular, columnar, or trapezoidal structure, while the pressure sensor 12 and temperature sensor 13 can be sheet-like, columnar, or rectangular structures. The positional relationship between the pressure sensor 12 and temperature sensor 13 can be either vertical or horizontal. All these structures and positional relationships fall within the protection scope of this application.

[0048] The specific structure and positional relationship of the housing 11, pressure sensor 12, and temperature sensor 13 of the intracranial probe 10 in this embodiment of the application will be described in detail below.

[0049] like Figures 1 to 5 As shown, in some embodiments, the intracranial probe 10 further includes a flexible support 14, the edge of which is flush with the table surface and in contact with the pressure sensor 12, and a temperature sensor 13 is disposed on the side of the flexible support 14 facing away from the window 111. The middle part of the flexible support 14 extends into the interior of the receiving chamber 112 and isolates the pressure sensor 12 from the temperature sensor 13.

[0050] In this embodiment, the flexible support 14 includes a silicone support, and the flexible support 14 can be configured as a structure similar to a channel steel. The two sides of the flexible support 14 are flush with the platform of the stepped structure 113, so as to flexibly support and install the pressure sensor 12, reducing the phenomenon of hard contact between the platform of the stepped structure 113 and the pressure sensor 12 and damaging the pressure sensor 12. The temperature sensor 13 is embedded in the middle of the flexible support 14, so that the temperature sensor 13 is located on the side of the flexible support 14 away from the window 111. This not only achieves the purpose of stabilizing the temperature sensor 13, but also achieves the purpose of isolating the pressure sensor 12 and the temperature sensor 13, reducing the phenomenon of heat transfer from the pressure sensor 12 to the temperature sensor 13. Moreover, the flexible support 14 can conduct heat of intracranial fluid to the temperature sensor 13, so that the heat of intracranial fluid around the intracranial probe 10 can be transferred to the temperature sensor 13, thereby achieving the purpose of the temperature sensor 13 sensing the intracranial temperature.

[0051] It should be noted that setting the flexible stent 14 as a silicone stent similar to a channel steel is only a preferred embodiment of this application and is not a limitation on the material and shape of the flexible stent 14. For example, in other embodiments, the flexible stent 14 can also be set as a bio-hydrogel stent similar to a tile. These structures and materials of the flexible stent 14 can achieve the purpose of integrating the pressure sensor 12 and the temperature sensor 13, which is beneficial to the miniaturization of the intracranial probe 10. Therefore, these adjustments to the structure and material of the flexible stent 14 also fall within the protection scope of the embodiments of this application.

[0052] In some embodiments, a channel is formed between the middle of the flexible support 14 and the back of the pressure sensor 12, the channel forming an airway communicating with standard air pressure, and the airway and intracranial fluid forming a pressure difference on both sides of the pressure sensor 12.

[0053] In this embodiment, the pressure sensor 12 includes a circuit board 121 and a pressure sensing diaphragm 122 disposed on the circuit board 121. The circuit board 121 is configured as a plate structure and has a sensing port communicating with the airway. The pressure sensing diaphragm 122 is disposed at the sensing port. The front of the pressure sensing diaphragm 122 bears the intracranial pressure of the intracranial fluid, and the back of the pressure sensing diaphragm 122 bears the external atmospheric pressure. Using atmospheric pressure as the zero point for measuring pressure, the difference between the intracranial pressure and atmospheric pressure borne by the pressure sensing diaphragm 122 is the intracranial pressure detected by the pressure sensor 12.

[0054] In some embodiments, the proximal end 23 of the housing 11 is provided with a through hole 114 communicating with the airway. The through hole 114 and the airway form a closed channel within the housing 11. The closed channel is configured to cooperate with the intracranial pressure catheter 30 and communicate with the standard air pressure through the intracranial pressure catheter 30.

[0055] In this embodiment, the size of the through hole 114 is set to match the size of the airway, and a baffle is provided around the through hole at the proximal end 23 of the housing 11. The intracranial pressure catheter 30 is configured to communicate with the through hole 114 and be sealed and connected with the baffle, thereby reducing leakage between the intracranial pressure catheter 30 and the through hole.

[0056] In addition, the intracranial pressure catheter 30 is arranged along the implantation path of the intracranial probe 10 and extends out of the body at the proximal end 23 of the implantation path to achieve communication with the standard air pressure. The through hole 114 and the airway form a closed channel in the shell 11, which can reduce the inflow of intracranial fluid into the shell 11 and affect the normal operation of the pressure sensor 12 and the temperature sensor 13, thereby improving the detection accuracy of the pressure sensor 12 and the temperature sensor 13.

[0057] like Figure 3 and Figure 4 As shown, in some embodiments, the wires of the temperature sensor 13 and / or the wires of the pressure sensor 12 extend into the channel and through the intracranial pressure catheter 30 to the outside of the intracranial probe 10.

[0058] In this embodiment, the temperature sensor 13 is provided with a temperature sensing line 131. The temperature sensing line 131 is hot-pressed and bent into a Π shape at the temperature sensor 13, and then extends through the intracranial pressure catheter 30 to the outside of the intracranial probe 10 and connects to the terminal 40 of the intracranial detection component 100. The temperature sensor 13 transmits the sensed intracranial temperature to the terminal 40 of the intracranial detection component 100 through the temperature sensing line 131, so that medical staff can view and analyze the intracranial temperature.

[0059] Similarly, the pressure sensing diaphragm 122 is provided with a pressure sensing line 123. The pressure sensing line 123 is heat-pressed and bent into a Π shape at the pressure sensing diaphragm 122, and then extends through the intracranial pressure catheter 30 to the outside of the intracranial probe 10 and connects to the terminal 40 of the intracranial detection component 100. The pressure sensing diaphragm 122 transmits the sensed intracranial pressure to the terminal 40 of the intracranial detection component 100 through the pressure sensing line 123, which is convenient for medical staff to view and analyze the intracranial pressure.

[0060] Furthermore, extending the wires of the temperature sensor 13 and / or the pressure sensor 12 into the channel can improve the utilization rate of the channel, thereby eliminating the need to set additional wire grooves inside the intracranial probe 10 and reducing the manufacturing difficulty of the intracranial probe 10.

[0061] like Figure 3 and Figure 4 As shown, in some embodiments, the pressure sensor 12 is configured as a plate-like structure, with the edge of the plate-like structure laid flat on the table surface via the edge of the flexible support 14.

[0062] In this embodiment, the pressure sensor 12 includes a circuit board 121 and a pressure-sensing diaphragm 122 disposed on the circuit board 121. The circuit board 121 is configured as a plate-like structure, and the platform of the stepped structure 113 is configured to be flush with the window 111 of the intracranial probe 10. The circuit board 121 is placed flat on the platform of the stepped structure 113, thereby enabling the pressure-sensing diaphragm 122 to sense the intracranial pressure at the window 111 of the intracranial probe 10 from the front, improving the measurement stability and accuracy of the pressure-sensing diaphragm 122. Furthermore, the flexible support 14 can buffer the circuit board 121, reducing the risk of damage to the control board due to rigid contact between the circuit board 121 and the stepped structure 113.

[0063] like Figure 3 and Figure 4 As shown, in some embodiments, the temperature sensor 13 is configured as a columnar structure, and the bottom of the receiving chamber 112 is provided with a flexible cylindrical support frame 15 that cooperates with the columnar structure.

[0064] In this embodiment, the temperature sensor 13 is configured as a columnar structure, which can improve the detection range of the temperature sensor 13. For example, the temperature sensor 13 can detect intracranial temperature in 360°. At the same time, the flexible cylindrical support frame 15 can support and buffer the temperature sensor 13, reducing the phenomenon of damage to the temperature sensor 13 due to hard contact between the temperature sensor 13 and the housing 11.

[0065] Specifically, during the assembly of the intracranial probe 10, a flexible cylindrical support frame 15 is first placed at the bottom of the receiving chamber 112. Then, a columnar temperature sensor 13 is placed on the flexible cylindrical support frame 15. Silicone is then poured onto the temperature sensor 13, the flexible cylindrical support frame 15, and the stepped structure 113. After the silicone solidifies, a flexible support 14 is formed that connects the stepped structure 113 and the temperature sensor 13. The flexible support 14 achieves the purpose of sealing and fixing the temperature sensor 13. At this time, the pressure sensor 12 can be placed on the platform of the stepped structure 113 and in contact with the edge of the flexible support 14. The platform of the stepped structure 113 and the edge of the flexible support 14 achieve the purpose of supporting the pressure sensor 12.

[0066] Furthermore, the end of the temperature sensor 13 extends along the length of the pressure sensor 12 and faces the window 111, so that the heat from the intracranial fluid around the intracranial probe 10 can be directly transferred to the temperature sensor 13 through the silicone, thereby improving the measurement sensitivity of the temperature sensor 13.

[0067] like Figure 3 and Figure 4 As shown, in some embodiments, the intracranial probe 10 also includes a sensing coating (not shown) for sensing intracranial pressure and temperature, the sensing coating covering the window 111 and sealing the pressure sensor 12 and the temperature sensor 13.

[0068] In this embodiment, the sensing coating is applied to the surface of the circuit board 121 to protect the circuit board 121 and the pressure sensing diaphragm 122, preventing the components of human tissue fluid from corroding the circuit board 121 and the pressure sensing diaphragm 122 and thus affecting the measurement accuracy. Furthermore, the sensing coating possesses specific characteristics such as high dielectric strength and good water vapor permeability, and can be made of materials such as Parylene, epoxy resin, or silicone resin. The sensing coating is applied after the hot-pressing process, enabling the sensing coating to transmit the pressure and temperature of the intracranial fluid to the pressure sensor 12 and the temperature sensor 13, thereby reducing the impact of the sensing coating on the measurement accuracy of the pressure sensor 12 and the temperature sensor 13.

[0069] like Figures 1 to 5 As shown, the second aspect of this application provides an intracranial detection assembly 100, which includes an intracranial probe 10 and a catheter assembly. The intracranial probe 10 is the same as the intracranial probe 10 according to the first aspect of this application. The catheter assembly includes a drainage tube 20 and an intracranial pressure catheter 30. The intracranial probe 10 is disposed inside the drainage tube 20. The drainage tube 20 is provided with a drainage port 211 corresponding to the window 111 of the intracranial probe 10. The intracranial pressure catheter 30 is disposed inside the drainage tube 20 and communicates with the through hole of the intracranial probe 10.

[0070] In this embodiment, the drainage tube 20 has a certain rigidity, which can provide good protection for the internal pressure sensor 12 and temperature sensor 13, preventing the entire intracranial probe 10 from failing due to external stress impacts and collisions. The drainage tube 20 should be made of biocompatible materials, such as polymer plastics, titanium alloys, stainless steel, ceramics, etc. During implantation, the intracranial probe 10 needs to pass through the surface of the body to reach the internal tissues. To prevent damage to human tissues and increase patient suffering, the drainage tube 20 should be made with a smooth curved surface without sharp edges. Specifically, the distal end 21 of the drainage tube 20 is set as an arc-shaped shell. A window 111 is opened in the middle of the drainage tube 20. The function of this window 111 is to allow the sensing surface of the pressure sensor 12 to directly contact the external environment to ensure measurement accuracy.

[0071] like Figures 1 to 5 As shown, in some embodiments, the intracranial probe 10 is disposed at the distal end 21 of the drainage tube 20, the drainage port 211 is disposed on the tube wall of the distal end 21, and the middle section 22 of the drainage tube 20 is also provided with a drainage hole 221 communicating with the window 111 on the side wall.

[0072] In this embodiment, by simultaneously draining the intracranial probe 10 through the drainage port 211 and the drainage hole 221, the flow stability of the fluid at the intracranial probe 10 can be improved, and the phenomenon of intracranial fluid concentrating at the drainage port 211 and acting on the intracranial probe 10, which would lead to detection distortion, can be reduced.

[0073] Furthermore, the intracranial detection component 100 also includes a drain valve 24, which is located at the proximal end 23 of the drainage tube 20 and communicates with the internal space of the drainage tube 20. It is used to drain the intracranial fluid in the drainage tube 20 to the outside of the human tissue, thereby achieving the purpose of regulating intracranial pressure.

[0074] The above description is merely a preferred embodiment of this application, but the scope of protection of this application is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this application should be included within the scope of protection of this application. Therefore, the scope of protection of this application should be determined by the scope of the claims.

Claims

1. An intracranial probe, characterized in that, include: The housing has a window, and the interior of the housing has a receiving chamber communicating with the window, and the side wall of the receiving chamber has a stepped structure; The sensor assembly, comprising a pressure sensor and a temperature sensor, is disposed within the containment chamber. The pressure sensor is placed on the platform of the stepped structure and faces the window. The temperature sensor is disposed inside the housing in a sealed cavity that isolates intracranial fluid. The sidewall of the stepped structure forms a channel between the pressure sensor and the temperature sensor and is connected to standard atmospheric pressure. The front of the pressure sensor is used to withstand the intracranial pressure of the intracranial fluid, and the back of the pressure sensor is used to withstand the external atmospheric pressure.

2. The intracranial probe according to claim 1, characterized in that, The intracranial probe also includes a flexible support, the edge of which is flush with the table surface and in contact with the pressure sensor. The temperature sensor is located on the side of the flexible support facing away from the window. The middle part of the flexible support extends into the interior of the receiving chamber and isolates the pressure sensor from the temperature sensor.

3. The intracranial probe according to claim 2, characterized in that, The flexible stent has a channel between its middle section and the back of the pressure sensor. The channel forms an airway that communicates with standard air pressure. The airway and the intracranial fluid create a pressure difference on both sides of the pressure sensor.

4. The intracranial probe according to claim 3, characterized in that, The proximal end of the housing is provided with a through hole communicating with the airway. The through hole and the airway form a closed channel within the housing. The closed channel is configured to cooperate with an intracranial pressure catheter and communicate with standard air pressure through the intracranial pressure catheter.

5. The intracranial probe according to claim 4, characterized in that, The wires of the temperature sensor and / or the wires of the pressure sensor extend into the channel and through the intracranial pressure catheter to the outside of the intracranial probe.

6. The intracranial probe according to any one of claims 2 to 5, characterized in that, The pressure sensor is configured as a plate-like structure, and the edge of the plate-like structure is laid flat on the table surface through the edge of the flexible support.

7. The intracranial probe according to any one of claims 1 to 5, characterized in that, The temperature sensor is configured as a columnar structure, and the bottom of the receiving chamber is provided with a flexible cylindrical support frame that cooperates with the columnar structure.

8. The intracranial probe according to any one of claims 1 to 5, characterized in that, The intracranial probe also includes a sensing coating that senses intracranial pressure and temperature, the sensing coating covering the window and sealing the pressure sensor and the temperature sensor.

9. An intracranial detection component, characterized in that, The intracranial detection component includes: An intracranial probe, wherein the intracranial probe is the intracranial probe according to any one of claims 1 to 8; The catheter assembly includes a drainage tube and an intracranial pressure catheter, wherein the intracranial probe is disposed inside the drainage tube, the drainage tube is provided with a drainage port corresponding to the window of the intracranial probe, and the intracranial pressure catheter is disposed inside the drainage tube and communicates with the through hole of the intracranial probe.

10. The intracranial detection component according to claim 9, characterized in that, The intracranial probe is positioned at the distal end of the drainage tube, the drainage port is positioned on the distal tube wall, and the middle section of the drainage tube is also provided with a drainage hole communicating with the window.

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