Multifunctional non-invasive transdermal drug delivery nanomizer

Abstract

The present application relates to the field of atomization instrument, disclose multifunctional noninvasive transdermal drug delivery nanometer atomization instrument, including shell and for atomization outflow atomization component, atomization component includes medicine box and piston rod can along the inner wall of medicine box sliding, the inside of the shell is provided with the adjustment assembly that is rotationally connected with piston rod, the inside of the shell is provided with the base for the adjustment assembly of movable arrangement, the surface of the base is slidably installed for the limiting assembly for realizing the limiting of adjustment assembly;The present application can adjust the rotation radius of adjustment assembly relative to the rotation center of base through the cooperation between adjustment assembly, limiting assembly, first fine adjustment assembly and piston rod etc., cooperate piston rod so that the outflow of atomization component also changes, and then the outflow of atomization component can be quickly and conveniently adjusted, so that the user can freely select the outflow that is suitable for his skin.

Description

Technical Field

[0001] This invention relates to the field of nebulizer technology, and in particular to a multifunctional, non-invasive transdermal drug delivery nanonebulizer. Background Technology

[0002] Nebulization refers to the process of dispersing a liquid into tiny droplets through a nozzle or high-speed airflow. The numerous dispersed droplets can capture particulate matter in a gas. Nebulizers are frequently used in dermatology for the treatment of allergic skin conditions, as well as in the treatment of respiratory diseases such as bronchitis and asthma.

[0003] Chinese invention patent publication number CN210904473U discloses a nebulized inhalation device for pediatric use, which includes a device body. A fixed sleeve is installed at the bottom of the device body, and a medicine tube is fixed inside the fixed sleeve. Liquid is injected into the fixed sleeve, and a heating wire is installed inside the fixed sleeve. It has the advantages of heating the medicine and changing the liquid output.

[0004] The device changes the liquid output by rotating the shaft, which in turn switches between the two atomizing nozzles to change the liquid output. However, during use, the amount of liquid output from the liquid tube to the atomizing nozzle remains unchanged. Over time, the small-diameter atomizing nozzle is subjected to greater impact due to the constant output, which leads to faster clogging and a reduced lifespan.

[0005] Therefore, it is necessary to provide a multifunctional, non-invasive transdermal drug delivery nanonebulizer to solve the above-mentioned technical problems. Summary of the Invention

[0006] The purpose of this invention is to provide a multifunctional, non-invasive transdermal drug delivery nanonebulizer to solve the problem in the background art where the amount of drug solution output from the tube to the atomizing nozzle cannot be changed during use.

[0007] To achieve the above objectives, the liquid is dispensed from the medicine tank by the reciprocating motion of the piston rod. The piston rod reciprocates by an adjustment component. By changing the rotation radius of the adjustment component, the stroke of the piston rod within the medicine tank is changed, thereby altering the amount of liquid output to the atomizing nozzle.

[0008] Based on the above ideas, the present invention provides the following technical solution: a multifunctional non-invasive transdermal drug delivery nanonebulizer, comprising a shell and a nebulizing component for nebulizing liquid, the nebulizing component comprising a medicine tank and a piston rod that can slide along the inner wall of the medicine tank, an adjustment component rotatably connected to the piston rod is provided inside the shell, a base for movably accommodating the adjustment component is provided inside the shell, a limiting component for limiting the adjustment component is slidably mounted on the surface of the base, a first fine-tuning component is provided through the surface of the base away from the motor, which is movably fitted to the limiting component and extends to the outside of the shell, and a motor that is drively connected to the first fine-tuning component is fixedly installed inside the shell;

[0009] When the motor is not started and the first fine-tuning component is pressed in the direction of the motor, the adjustment component is driven to rotate through the limit component, which can realize the adjustment of the rotation radius of the adjustment component relative to the base.

[0010] As a further aspect of the present invention: the adjusting assembly includes a gear, a connecting rod that is rotatably mounted on one side of the gear and rotatably engaged with the piston rod, a short rod that is rotatably engaged with the base is fixedly mounted on the other side of the gear, and a ratchet that engages with the first fine-tuning assembly is fixedly mounted on the end of the short rod away from the gear.

[0011] As a further embodiment of the present invention: the limiting component includes a locking tooth that slides with the base and is used to limit the adjustment component; a first spring is fixedly installed between the locking tooth and the base; a cantilever is fixedly installed on the surface of the locking tooth; and a pawl that engages with a ratchet is rotatably installed on the surface of the cantilever via a torsion spring.

[0012] As a further aspect of the present invention: the first fine-tuning component includes an outer sleeve that rotates with the housing, is fixedly connected to the base, and is driven by a motor via a belt. The inner side of the outer sleeve is fitted with a key sleeve that extends into the interior of the base via a key shaft. A long plate that movably fits against the inclined surface of the locking teeth is fixedly installed on the outer surface of the key sleeve. A second spring is fixedly installed between the long plate and the inner wall of the base.

[0013] As a further aspect of the present invention: the key sleeve is provided with a second fine-tuning component extending into the base. The first fine-tuning component further includes a slider, which penetrates the surface of the long plate and slides parallel to it. The end of the slider away from the second fine-tuning component is also provided with the same inclined surface as the long plate. A block is slidably mounted on the other end of the slider. A wedge-shaped hole is opened on the surface of the block to movably fit with the second fine-tuning component. A fifth spring for resetting the block is fixedly installed between the block and the long plate. A positioning component is fixedly installed on the side of the second fine-tuning component away from the key sleeve. A sliding component that cooperates with the positioning component to limit the movement of the second fine-tuning component is fixedly installed inside the base.

[0014] As a further aspect of the present invention: the second fine-tuning component includes a key rod that is key-shaft-assembled with the key sleeve, and a support rod that is fixedly connected to the positioning component is fixedly installed at the end of the key rod near the gear. A protrusion and a wedge block that movably fits the wedge hole are fixedly installed on the surface of the support rod. A third spring for resetting the protrusion is fixedly installed between the protrusion and the inner wall of the base.

[0015] As a further aspect of the present invention: the positioning component includes a ring block fixedly connected to the second fine-tuning component, the ring block has a placement groove inside, the placement groove has a locking block inside, the outer surface of the locking block is fixedly installed with a baffle, and a fourth spring is fixedly installed between the baffle and the groove wall of the placement groove.

[0016] As a further embodiment of the present invention: the atomizing assembly further includes an atomizing nozzle connected to the medicine box, the atomizing nozzle extending to the outside of the housing, and a one-way valve is provided on the atomizing nozzle.

[0017] As a further embodiment of the present invention: the sliding assembly includes a horizontal block fixedly connected to the base, a round rod fixedly installed on the surface of the horizontal block near the ring block, a collar movably sleeved on the outer surface of the round rod, both sides of the collar inclined towards the center of the collar to form an inclined surface, a semi-circular block fixedly installed at the end of the round rod away from the horizontal block, and a groove adapted to the inclined surface of the collar is opened on the surface of the ring block near the round rod.

[0018] Compared with the prior art, the beneficial effects of the present invention are: by cooperating with the adjusting component, the limiting component, the first fine-tuning component and the piston rod, the rotation radius of the adjusting component relative to the rotation center of the base can be adjusted, and the liquid output of the atomizing component can also be changed in conjunction with the piston rod, thereby allowing the liquid output of the atomizing component to be quickly and conveniently adjusted, allowing users to freely choose the liquid output that is suitable for their skin and obtain a better drug delivery effect. Attached Figure Description

[0019] The present invention will be further described below with reference to the accompanying drawings and embodiments:

[0020] Figure 1 This is a schematic diagram of the overall structure of the present invention;

[0021] Figure 2 This is a schematic diagram of the internal structure of the housing of the present invention;

[0022] Figure 3 This is a schematic diagram of the internal structure of the base of the present invention;

[0023] Figure 4 This is a side view of the internal structure of the base of the present invention;

[0024] Figure 5 for Figure 3 Enlarged view of the structure at point A in the middle;

[0025] Figure 6 This is a schematic diagram of the outer sleeve, key sleeve, and key rod structure of the present invention;

[0026] Figure 7 for Figure 4 Enlarged view of the structure at point C;

[0027] Figure 8This is a schematic diagram of the positioning component of the present invention;

[0028] Figure 9 for Figure 3 Enlarged view of the structure at point B in the middle;

[0029] Figure 10 This is a schematic diagram of the slider, long plate, and locking teeth structure of the present invention.

[0030] In the diagram: 1. Housing; 2. Atomizing assembly; 3. Motor; 4. Base; 5. Adjustment assembly; 6. Limiting assembly; 7. First fine-tuning assembly; 8. Second fine-tuning assembly; 9. Positioning assembly; 10. Sliding assembly; 201. Medicine box; 202. Piston rod; 203. Atomizing nozzle; 501. Gear; 502. Connecting rod; 503. Short rod; 504. Ratchet; 601. Gear; 602. First spring; 603. Cantilever; 604. Claw; 701. Key sleeve; 7 02. Long plate; 703. Block; 704. Wedge hole; 705. Slider; 706. Second spring; 707. Outer sleeve; 801. Key rod; 802. Support rod; 803. Protrusion; 804. Third spring; 805. Wedge block; 901. Ring block; 902. Placement slot; 903. Locking block; 904. Baffle; 905. Fourth spring; 1001. Horizontal block; 1002. Round rod; 1003. Collar; 1004. Semicircular block; 1005. Groove. Detailed Implementation

[0031] Example 1:

[0032] Please see Figures 1 to 4 This invention provides a multifunctional non-invasive transdermal drug delivery nanonebulizer: it includes a housing 1 and a nebulizing component 2 for nebulizing liquid. The nebulizing component 2 includes a medicine tank 201 and a piston rod 202 that can slide along the inner wall of the medicine tank 201. The sliding fit between the medicine tank 201 and the inner piston rod 202 is a well-established technology and will not be described in detail here. The medicine tank 201 contains a liquid medicine. An adjustment component 5 that is rotatably connected to the piston rod 202 is provided inside the housing 1. A base 4 for movably accommodating the adjustment component 5 is provided inside the housing 1. The adjustment component 5 is located at an eccentric position on the base 4, i.e., not at the rotation center of the base 4. A limiting component 6 for limiting the adjustment component 5 is slidably mounted on the surface of the base 4. A first fine-tuning component 7 that is movably fitted to the limiting component 6 and extends to the outside of the housing 1 is provided through the surface of the base 4 away from the motor 3. A motor 3 that is pulsatorically connected to the first fine-tuning component 7 is fixedly installed inside the housing 1.

[0033] When the motor 3 starts, it drives the first fine-tuning component 7 to rotate. The first fine-tuning component 7 drives the base 4 to rotate. The base 4 drives the piston rod 202 to move up and down along the inner wall of the medicine tank 201 through the limiting component 6 and the adjusting component 5, which can realize the atomization of the liquid by the atomizing component 2.

[0034] When the motor 3 is not started and the first fine-tuning component 7 is pressed in the direction of the motor 3, the adjusting component 5 is rotated by the limiting component 6, which can adjust the rotation radius of the adjusting component 5. Then, the first fine-tuning component 7 is released, and the limiting component 6 limits the adjusting component 5 again. When the motor 3 is started again, the piston rod 202 is driven to move up and down through the first fine-tuning component 7, the limiting component 6, the base 4 and the adjusting component 5, which can adjust the liquid output of the atomizing component 2.

[0035] In this embodiment, preferably, when in use, the starter motor 3 drives the first fine-tuning component 7 to rotate, and the first fine-tuning component 7 drives the base 4 to rotate. Because of the limiting component 6, the adjusting component 5 can rotate synchronously with the base 4. When the adjusting component 5 rotates, it drives the piston rod 202 to move up and down along the inner wall of the medicine box 201, which can realize the atomization of the liquid by the nebulizing component 2 and perform non-invasive transdermal drug delivery to the user.

[0036] Turn off motor 3 and press the first fine-tuning component 7 in the direction of motor 3. The first fine-tuning component 7 can drive the limiting component 6 away from the adjusting component 5. At this time, the adjusting component 5 is released from the limit and can rotate freely. When the limiting component 6 moves away from the adjusting component 5, it will also drive the adjusting component 5 to rotate. Because the adjusting component 5 and the base 4 are eccentrically set, the rotation of the adjusting component 5 changes the distance between the center of rotation of the adjusting component 5 and the base 4, that is, the rotation radius of the adjusting component 5 is adjusted. Then release the first fine-tuning component 7 so that it automatically resets in the direction away from motor 3, while the limiting component 6... To reset the first fine-tuning component 7, it also moves closer to the adjustment component 5 to re-limit the adjustment component 5. At this time, the motor 3 is restarted. Through the cooperation of the first fine-tuning component 7, the limiting component 6, the base 4 and the adjustment component 5, the piston rod 202 can continue to move up and down, so that the atomizing component 2 can complete the atomization and liquid output. Because the rotation radius of the adjustment component 5 changes, the liquid output of the atomizing component 2 also changes. Thus, the liquid output of the atomizing component 2 can be quickly and conveniently adjusted, allowing the user to freely choose the liquid output that is suitable for their skin and obtain a better drug delivery effect.

[0037] Example 2:

[0038] Please see Figures 1 to 6Based on Embodiment 1, the atomizing component 2 also includes an atomizing nozzle 203 connected to the medicine box 201. The atomizing nozzle 203 extends to the outside of the housing 1. The atomizing nozzle 203 is equipped with a one-way valve that allows air to exit but not to enter the medicine box 201. The medicine box 201 is also connected to an airbag for replenishing air to the medicine box 201. The replenishment is also one-way, allowing air to enter the medicine box 201, thus stabilizing the air pressure inside the medicine box 201. The atomizing nozzle 203, the airbag, and the one-way valve are existing mature technologies and will not be described in detail here.

[0039] The adjusting component 5 includes a gear 501, which is offset from the rotation center of the base 4, i.e., eccentrically set, so that the movement of the piston rod 202 driven by the gear 501 through the connecting rod 502 can be smoother and the liquid discharge can be more stable. A connecting rod 502 that is rotatably mounted on one side of the gear 501 and rotatably engaged with the piston rod 202 is mounted on the other side of the gear 501. A short rod 503 that is rotatably engaged with the base 4 is fixedly mounted on the end of the short rod 503 away from the gear 501. A ratchet 504 that engages with the first fine-tuning component 7 is fixedly mounted on the end of the short rod 503. The first fine-tuning component 7 can realize the limiting and rotation of the ratchet 504. The ratchet 504 can be synchronously adjusted with the gear 501 through the short rod 503.

[0040] The limiting component 6 includes a locking tooth 601 that slides with the base 4 and is used to limit the gear 501. The locking tooth 601 is adapted to the gear 501 and can move closer to or further away from the gear 501 along the base 4. A first spring 602 is fixedly installed between the surface of the locking tooth 601 away from the gear 501 and the base 4. Under the action of the first spring 602, the locking tooth 601 is always engaged with the gear 501. The surface of the locking tooth 601 near the first fine-tuning component 7 is set as an inclined surface. A cantilever 603 is fixedly installed on the surface of the locking tooth 601. A pawl 604 that engages with the ratchet 504 is rotatably installed on the surface of the cantilever 603 through a torsion spring. Under the action of the torsion spring, the pawl 604 can only rotate counterclockwise and cannot rotate clockwise.

[0041] The first fine-tuning component 7 includes an outer sleeve 707 that is rotatably fitted to the housing 1, fixedly connected to the base 4, and driven by the motor 3 via a belt. Inside the outer sleeve 707, a key sleeve 701 extending into the base 4 is mounted via a key shaft. The outer sleeve 707 can drive the key sleeve 701 to rotate synchronously, and the key sleeve 701 can slide back and forth along the outer sleeve 707. A long plate 702 that is movably fitted with the inclined surface of the retaining tooth 601 is fixedly installed on the outer surface of the key sleeve 701. That is, the side of the long plate 702 near the retaining tooth 601 is also set with the same inclined surface as the retaining tooth 601. The long plate 702 is located inside the base 4, and a second spring 706 is fixedly installed between the long plate 702 and the inner wall of the base 4 to realize the reset of the long plate 702.

[0042] In this embodiment, preferably: during use, the starter motor 3 drives the outer sleeve 707 to rotate via a transmission belt, the outer sleeve 707 drives the base 4 to rotate synchronously, and the base 4 drives the locking teeth 601 to rotate. Because the locking teeth 601 engages with the gear 501 and the rotation center of the gear 501 is eccentrically set with respect to the base 4, the gear 501 rotates eccentrically relative to the base 4. When the gear 501 rotates, it drives the piston rod 202 to move up and down along the inner wall of the medicine box 201 via the connecting rod 502, which can deliver the liquid medicine in the medicine box 201 to the nebulizer nozzle 203. The liquid medicine is then atomized and sprayed out through the nebulizer nozzle 203 to deliver the medicine to the user for non-invasive transdermal drug delivery. During this process, the key sleeve 701 and the outer sleeve 707 rotate synchronously, so that the long plate 702 and the locking teeth 601 also remain in a close fit and do not move.

[0043] When the motor 3 is turned off and does not drive the outer sleeve 707 to rotate, neither the base 4 nor the key sleeve 701 rotates. At this time, the key sleeve 701 is pressed towards the motor 3, which drives the long plate 702 to move towards the locking tooth 601 and pulls the first spring 602. The inclined surface of the long plate 702 presses against the inclined surface of the locking tooth 601, causing the locking tooth 601 to move away from the gear 501 and press against the second spring 706. After the locking tooth 601 separates from the gear 501, the limiting of the gear 501 is released. When the locking tooth 601 moves away from the gear 501, it drives the cantilever 603 to move synchronously. The cantilever 603 drives the ratchet 504 to rotate through the pawl 604. The ratchet 504 drives the gear 501 to rotate through the short rod 503. The gear 501 drives the connecting rod 502 to deflect, which changes the distance between the connecting rod 502 and the rotation center of the base 4, thus changing the rotation radius of the connecting rod 502. At this time, the key sleeve 701 is released. Under the action of the first spring 602, the key sleeve 701 and the long plate 702 automatically reset to the opposite direction away from the motor 3. The long plate 702 releases the pressure on the locking tooth 601. Under the action of the second spring 706, the locking tooth 601 is relatively close to the gear 501. Then, the locking tooth 601 achieves the limitation of the gear 501, so that the gear 501 cannot rotate on its own. When the locking tooth 601 rises, it drives the pawl 604 to rise through the cantilever 603. Because of the setting of the torsion spring, the pawl 604 can rotate counterclockwise. When the pawl 604 rises, it does not drive the ratchet 504 to rotate. At this point, starting the motor 3 again drives the base 4 and key sleeve 701 to rotate via the belt and outer sleeve 707. The base 4 drives the gear 501 to rotate via the locking teeth 601. The gear 501 drives the piston rod 202 to move up and down reciprocally via the connecting rod 502, which works with the atomizing nozzle 203 to complete the atomization of the liquid. Because the rotation radius of the connecting rod 502 changes, the liquid output of the atomizing nozzle 203 also changes in conjunction with the piston rod 202 and the medicine tank 201. The atomization volume can be easily adjusted by simply pressing the key sleeve 701. The key sleeve 701 will automatically reset and will not affect the normal liquid output of the piston rod 202. At the same time, by pressing the key sleeve 701 a different number of times, different atomization volumes can be achieved, allowing users to adjust it arbitrarily according to their own needs and preferences. It can be adjusted in advance when the liquid is not being dispensed, or it can be adjusted on the spot when the liquid is being dispensed, providing more diverse options, simple operation, and higher practicality.

[0044] Example 3:

[0045] Please see Figures 1 to 10Based on Embodiment 2, the key sleeve 701 has a second fine-tuning component 8 extending into the base 4. The first fine-tuning component 7 also includes a slider 705, which penetrates the surface of the long plate 702 and slides alongside it. The end of the slider 705 away from the second fine-tuning component 8 is also set with the same inclined surface as the long plate 702. A block 703 is slidably mounted on the other end of the slider 705. The slider 705 can slide along the block 703, and the sliding direction is relatively closer to or away from the key sleeve 701. At the same time, the block 703 and the slider 705 will not separate, that is, the block 703... When 703 moves relative to the long plate 702, it will drive the slider 705 to move synchronously; the surface of the block 703 is provided with a wedge-shaped hole 704 that is movably fitted with the second fine-tuning component 8; a fifth spring (not shown in the figure) for resetting the block 703 is fixedly installed between the surface of the block 703 and the long plate 702; when the block 703 moves away from the long plate 702, the fifth spring will be stretched; a positioning component 9 is fixedly installed on the side of the second fine-tuning component 8 away from the key sleeve 701; a sliding component 10 that cooperates with the positioning component 9 to limit the second fine-tuning component 8 is fixedly installed inside the base 4.

[0046] The second fine-tuning component 8 includes a key rod 801 that slides with the key sleeve 701. The key sleeve 701 and the key rod 801 are also assembled in a key shaft manner, that is, the key sleeve 701 can drive the key rod 801 to rotate synchronously, and the key rod 801 can slide back and forth along the key sleeve 701. A support rod 802 that is fixedly connected to the positioning component 9 is fixedly installed at the end of the key rod 801 near the gear 501. A protrusion 803 and a wedge block 805 that movably fits with the wedge hole 704 are fixedly installed on the surface of the support rod 802. When the wedge block 805 moves closer to the gear 501, it will drive the block 703 to descend through the wedge hole 704. A third spring 804 is fixedly installed between the protrusion 803 and the inner wall of the base 4 to realize the reset of the protrusion 803.

[0047] The positioning component 9 includes a ring block 901 fixedly connected to the support rod 802. The ring block 901 has a placement groove 902 inside. A locking block 903 is provided inside the placement groove 902. A baffle 904 is fixedly installed on the outer surface of the locking block 903. A fourth spring 905 is fixedly installed between the baffle 904 and the groove wall of the placement groove 902. When the locking block 903 moves into the placement groove 902, it will squeeze the fourth spring 905. The fourth spring 905 cooperates with the baffle 904 to limit the locking block 903.

[0048] The sliding assembly 10 includes a horizontal block 1001 fixedly connected to the base 4. A round rod 1002 is fixedly installed on the surface of the horizontal block 1001 near the ring block 901. A collar 1003 is movably sleeved on the outer surface of the round rod 1002. The collar 1003 can slide back and forth along the round rod 1002. Both sides of the collar 1003 are inclined towards the center of the collar 1003 to form an inclined surface. A semi-circular block 1004 is fixedly installed at the end of the round rod 1002 away from the horizontal block 1001. The semi-circular block 1004 is adapted to the inner diameter of the ring block 901, that is, the semi-circular block 1004 can pass through the ring block 901. A groove 1005 adapted to the inclined surface of the collar 1003 is opened on the surface of the ring block 901 near the round rod 1002, that is, the collar 1003 can engage with the semi-circular block 1004. After engagement, only one side of the inclined surface of the collar 1003 is exposed, and the other side of the inclined surface enters the groove 1005.

[0049] In this embodiment, preferably: while the long plate 702 is moved by the key sleeve 701, and the gear 501 and connecting rod 502 are rotated in conjunction with the pawl 601, pawl 604, and ratchet 504, the key rod 801 can also be pressed towards the motor 3. The key rod 801 drives the support rod 802, the protrusion 803, and the wedge block 805 to move closer to the block 703. When the protrusion 803 moves, it stretches the third spring 804. When the wedge block 805 moves, it cooperates with the wedge hole 704 to press the block 703, causing it to descend. The block 703 presses the fifth spring and drives the slider 705 to descend. After the slider 705 descends, its inclined surface connects with the inclined surface of the long plate 702. When the support rod 802 moves, it drives the ring block 901 to move. The ring block 901 drives the locking block 903 to move and contact the semicircular block 1004. The locking block 903 first moves towards the placement groove 902 and squeezes the fourth spring 905. Then, under the action of the fourth spring 905, it engages with the plane of the semicircular block 1004, which can limit the locking block 903 so that it can only move towards the gear 501 and cannot move away from the gear 501. After the locking block 903 is limited, the key rod 801, the support rod 802 and the wedge block 805 are also limited, thus keeping the square block 703 and the slider 705 stationary.

[0050] Then, press the key sleeve 701 towards the motor 3. Through the cooperation of the inclined surfaces of the long plate 702, the slider 705, and the tooth 601, the tooth 601 is moved away from the gear 501. Because the slider 705 has been added this time, the distance between the tooth 601 and the gear 501 increases after the tooth 601 moves. The distance that the tooth 601 moves through the cantilever 603 to drive the pawl 604 also increases. The angle at which the pawl 604 drives the ratchet 504 to rotate also increases. With the help of the short rod 503, the rotation amplitude of the gear 501 and the connecting rod 502 also increases, thereby realizing a large adjustment of the connecting rod 502. The position change of the connecting rod 502 is greater, that is, the rotation radius changes faster. It not only realizes the adjustment of the atomization amount, but also has a larger adjustment range and a larger change in the single liquid output compared to the second embodiment. It can be used when the user is not satisfied with slowly adjusting the liquid output and wants to increase the liquid output at one time.

[0051] When the user does not want to increase the liquid volume at once and wants to return to gradual adjustment, pressing the key lever 801 again moves the support lever 802 closer to the block 703. The support lever 802 then moves the ring block 901, which in turn moves the locking block 903 to contact the collar 1003. Because the collar 1003 can slide along the round rod 1002, the locking block 903 first moves the collar 1003 towards the horizontal block 1001 and abuts against it. At this time, the collar 1003... The position no longer changes, while the locking block 903 continues to move, first contacting one inclined surface of the collar 1003. At this time, the locking block 903 moves towards the placement groove 902 and squeezes the fourth spring 905. Then, under the action of the fourth spring 905, it engages with the other inclined surface of the collar 1003. Then, the key rod 801 is released, and under the action of the third spring 804, the key rod 801, the protrusion 803, the support rod 802, and the wedge block 805 reset in the direction away from the motor 3. The support rod 802 drives the ring block 901 and the locking block 903 to move synchronously. The locking block 903 first drives the collar 1003 to move towards the semicircular block 1004, so that one inclined surface of the locking block 903 engages with the groove 1005 of the semicircular block 1004. At this time, the locking block 903 can slide along the groove on the other inclined surface of the collar 1003. Finally, the locking block 903 separates from the semicircular block 1004, and the ring block 901 continues to move with the support rod 802. The reset of the wedge block 805 cooperates with the wedge shape. Hole 704 releases the pressure on block 703. Under the action of the fifth spring, block 703 drives slider 705 to rise, and slider 705 and its inclined surface are hidden in long plate 702. At this time, long plate 702 is moved by key sleeve 701. When the gear 501 and connecting rod 502 are rotated in conjunction with the structure of tooth 601, pawl 604 and ratchet 504, the inclined surface of slider 705 is reduced, so the adjustment amount returns to a smaller amount, that is, it returns to the process of slow step-by-step adjustment.

[0052] Through the cooperation of structures such as the long plate 702, the locking teeth 601, the locking claws 604, and the ratchet 504, the connecting rod 502 can be adjusted in small increments, allowing the user to gradually adjust it to find the appropriate liquid output. When the user realizes that the current liquid output is far from their satisfaction, through the cooperation of structures such as the wedge block 805, the slider 705, the locking block 903, and the collar 1003, the connecting rod 502 can be adjusted in larger increments, allowing for a larger single adjustment of the atomization volume. This enables the user to quickly adjust to a near-satisfactory atomization volume, providing more diverse options and simpler operation. The eccentric design of the gear 501 and the base 4 further enhances the user's experience. The design ensures smoother movement of the piston rod 202 driven by the connecting rod 502, resulting in a more stable liquid output from the atomizing nozzle 203 and preventing rapid spraying of the atomized liquid, thus ensuring a continuous and stable spray. Through the coordination of the key sleeve 701, key rod 801, block 703, and slider 705, adjustments for smaller and larger atomization volumes can be combined as needed, allowing users to quickly obtain a satisfactory atomization volume without interference. The operation is convenient and effortless, requiring only the pressing of key sleeve 701 or key rod 801, reducing the user's workload and meeting more practical needs.

[0053] The working principle of this invention is as follows: When in use, the starter motor 3 drives the outer sleeve 707 to rotate via the transmission belt. The outer sleeve 707 drives the base 4 to rotate synchronously. The base 4 drives the gear 501 to rotate eccentrically via the locking teeth 601. When the gear 501 rotates, it drives the piston rod 202 to move up and down along the inner wall of the medicine box 201 via the connecting rod 502. This can deliver the liquid medicine in the medicine box 201 to the nebulizer nozzle 203. The liquid is then atomized and sprayed out through the nebulizer nozzle 203 to deliver the medicine to the user through non-invasive transdermal drug delivery.

[0054] When motor 3 is turned off and does not rotate the outer sleeve 707, press the key sleeve 701 towards motor 3. This causes the long plate 702 to press the inclined surface of the retaining tooth 601, making the retaining tooth 601 relatively away from the gear 501. When the retaining tooth 601 moves away from the gear 501, it causes the cantilever 603 to move synchronously. The cantilever 603 drives the ratchet 504 to rotate through the pawl 604. The ratchet 504 deflects through the short rod 503 and the connecting rod 502 of the gear 501, changing the rotation radius of the connecting rod 502. At this time, releasing the key sleeve 701 allows the long plate 702 to automatically reset. The retaining tooth 601 then moves closer to the gear 501, thus limiting the gear 501. When motor 3 is restarted, the atomization process resumes. Because the rotation radius of the connecting rod 502 has changed, the liquid output of the atomizing nozzle 203 also changes in conjunction with the piston rod 202 and the medicine tank 201.

[0055] Alternatively, the key lever 801 can be pressed first. The key lever 801 drives the support rod 802 and the wedge block 805 to move closer to the cube 703. When the wedge block 805 moves, it cooperates with the wedge hole 704 to press the cube 703, causing the slider 705 to descend. After the slider 705 descends, its inclined surface connects with the inclined surface of the long plate 702 and remains flush. When the support rod 802 moves, it drives the ring block 901 to move. The ring block 901 drives the locking block 903 to move and engage with the plane of the semicircular block 1004, which can realize the locking block 903 and the key lever. Limiting of 801 and support rod 802; then press key sleeve 701, through the cooperation of the inclined surface of long plate 702, inclined surface of slider 705 and inclined surface of cleat 601, etc., drive cleat 601 to move away from gear 501. Because the inclined surface of slider 705 is added this time, the angle of rotation of cleat 604 driving ratchet 504 is also increased, which makes the rotation amplitude of gear 501 and connecting rod 502 larger, thereby realizing a large adjustment of connecting rod 502. During adjustment, a larger liquid output can be increased at one time.

[0056] When the user no longer wants to increase the liquid output at once and wants to return to gradual adjustment, pressing the key lever 801 again moves the support rod 802 closer to the block 703, causing the locking block 903 to engage with the collar 1003. Then, releasing the key lever 801, under the action of the third spring 804, the key lever 801, support rod 802, and wedge block 805 return to their original positions away from the motor 3. The support rod 802 then causes the locking block 903 to finally separate from the semicircular block 1004, and the wedge block 805... The wedge hole 704 releases the pressure on the block 703, and the block 703 drives the slider 705 to rise. The slider 705 and its inclined surface are then hidden in the long plate 702. At this time, the connecting rod 502 is adjusted to rotate through the long plate 702 in conjunction with the tooth 601, pawl 604 and ratchet 504. Because the inclined surface of the slider 705 is reduced, the adjustment amount returns to a smaller amount, that is, it returns to the process of slow and step-by-step adjustment. The two can be used together or separately, making it more versatile.

Claims

1. A multifunctional, non-invasive transdermal drug delivery nanonebulizer, comprising a housing and a nebulizing assembly for nebulizing liquid, the nebulizing assembly comprising a medicine tank and a piston rod that can slide along the inner wall of the medicine tank, characterized in that: The inside of the shell is provided with an adjusting assembly in rotational connection with the piston rod, the inside of the shell is provided with a base for movably arranging the adjusting assembly, the surface of the base is slidably provided with a limiting assembly for limiting the adjusting assembly, the surface of the base away from the motor is throughly provided with a first fine adjustment assembly in movable abutment with the limiting assembly and extending to the outside of the shell, the inside of the shell is fixedly provided with a motor in transmission connection with the first fine adjustment assembly; When the motor is not started and the first fine adjustment assembly is pressed towards the motor, the adjusting assembly is driven to rotate by the limiting assembly, so as to adjust the rotating radius of the adjusting assembly relative to the base; The adjusting assembly comprises a gear, one side of the gear is rotatably provided with a connecting rod in rotational cooperation with the piston rod, the other side of the gear is fixedly provided with a short rod in rotational cooperation with the base, and the end of the short rod away from the gear is fixedly provided with a ratchet wheel in engagement with the first fine adjustment assembly; The first fine adjustment assembly comprises an outer sleeve in rotational cooperation with the shell, fixed connection with the base and transmission connection with the motor through a belt, the inside of the outer sleeve is throughly provided with a key sleeve extending to the inside of the base through a key shaft type assembly, the outer surface of the key sleeve is fixedly provided with a long plate in movable abutment with the clamping tooth inclined surface, and the long plate and the inner wall of the base are fixedly provided with a second spring; The inside of the key sleeve is provided with a second fine adjustment assembly extending to the inside of the base, the first fine adjustment assembly further comprises a sliding block, the surface of the sliding block penetrates through the long plate and is in sliding cooperation with the long plate, one end of the sliding block away from the second fine adjustment assembly is also provided with the same inclined surface as the long plate, the other end of the sliding block is slidably provided with a square block, the surface of the square block is provided with a wedge-shaped hole in movable abutment with the second fine adjustment assembly, the square block and the long plate are fixedly provided with a fifth spring for resetting the square block, one side of the second fine adjustment assembly away from the key sleeve is fixedly provided with a positioning assembly, and the inside of the base is fixedly provided with a sliding assembly in cooperation with the positioning assembly to limit the second fine adjustment assembly.

2. The multifunctional non-invasive transdermal drug delivery nanomizer according to claim 1, characterized in that: The limiting assembly comprises a clamping tooth in sliding cooperation with the base and used for limiting the adjusting assembly, the clamping tooth and the base are fixedly provided with a first spring, the surface of the clamping tooth is fixedly provided with a cantilever, and the surface of the cantilever is rotatably provided with a clamping jaw in engagement with the ratchet wheel through a torsion spring.

3. The multifunctional non-invasive transdermal drug delivery nanomizer according to claim 2, characterized in that: The second fine adjustment assembly comprises a key rod in key shaft type assembly with the key sleeve, the end of the key rod close to the gear is fixedly provided with a support rod in fixed connection with the positioning assembly, the surface of the support rod is fixedly provided with a convex part and a wedge-shaped block in movable abutment with the wedge-shaped hole, and the convex part and the inner wall of the base are fixedly provided with a third spring for resetting the convex part.

4. The multifunctional non-invasive transdermal drug delivery nanomizer according to claim 3, characterized in that: The positioning assembly comprises a ring block in fixed connection with the second fine adjustment assembly, the inside of the ring block is provided with a placing groove, the inside of the placing groove is provided with a clamping block, the outer surface of the clamping block is fixedly provided with a baffle, and the baffle and the groove wall of the placing groove are fixedly provided with a fourth spring.

5. The multifunctional noninvasive transdermal drug delivery nanomizer according to any one of claims 1-4, characterized in that: The atomization assembly further comprises an atomization nozzle in connection with the medicine box, the atomization nozzle extends to the outside of the shell, and the atomization nozzle is provided with a one-way valve.

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