An injection system

Abstract

The present invention relates to an injection system. The injection system comprises an injection device and a guide part capable of guiding the injection device to inject at a correct position and at a correct angle, wherein the guide part comprises a detection unit, a control unit and an image guidance unit, and when the detection unit detects that the injection device enters a preset first-level injectable area, the image guidance unit turns on an image guidance function; when the detection unit detects that the injection device enters a preset second-level injectable area, the image guidance unit generates a preset acupuncture position in an image provided under the image guidance function, wherein the first-level injectable area is larger than the second-level injectable area.

Description

Technical Field

[0001] The present invention relates to the technical field of medical machinery, and in particular to an injection system. Background Art

[0002] Drugs are often dispensed using cartridges, such as glass syringes, which have a barrel with a needle at one end and a plunger slidably inserted into the other end and connected to a rubber stopper. Such cartridges are often referred to as "prefilled syringes" because they contain a specific dose or volume of drug when they are initially provided, as compared to conventional syringes, which are shipped empty and need to be filled by the user before an injection can be made.

[0003] Stem cell transplantation is currently used in the clinic for skin aging. For example, adipose-derived mesenchymal stem cells (ADSCs) in adipose tissue play a vital role in maintaining the survival and renewal of adipose tissue.

[0004] At present, stem cells used for treatment or facial repair can enter the human body through intramuscular injection, puncture injection or intravenous injection. For example, the new stem cell drug Stempeucel is currently used to inject into the lower limbs to treat severe limb ischemia caused by Buerger's disease or atherosclerotic peripheral arterial disease. Stem cells have the function of repairing muscle damage. At present, treatment methods to repair muscle damage or facial filling through intramuscular injection have been applied. Like drug injection, stem cell transplantation also requires injection equipment and is transplanted through intravenous injection, lumbar puncture injection and other methods.

[0005] The Chinese patent with publication number CN105586248B discloses a special stem cell rapid extraction device, which is mainly used in the clean environment of the operating room. The propulsion device moves the fat tissue in the syringe back and forth in the two syringes. After all the tissues are finally entered into the collection syringe, the collection syringe can be used to inject the obtained stem cells into the human body. A small enclosed space is formed between the three syringes, and the fat tissue has very little contact with the outside world, and the risk of contamination of the extracted stem cells is greatly reduced.

[0006] During the actual injection process, in addition to preventing contamination, injecting into the correct location is also a major factor affecting the correct effect of stem cell transplantation.

[0007] A Chinese patent with publication number CN105477769B discloses a stem cell introduction device, which includes a hollow outer sleeve, a hollow needle core and a hollow catheter; the outer sleeve is provided with a cursor that can move up and down along one side of the outer wall of the outer sleeve, and the other side of the outer wall of the outer sleeve is provided with a digital scale mark protruding from the outer wall surface, when the cursor moves to the digital scale mark, the cursor is rotated so that the cursor is fixed between or on the digital scale mark; the head end of the needle core is provided with a spike portion, the tail end of the needle core is connected to one end of the first syringe interface, and the spike portion is exposed by two millimeters when the needle core is fully inserted into the hollow part of the outer sleeve; the proximal end of the catheter is connected to the other end of the first syringe interface, and the distal end of the catheter is connected to the second syringe interface.

[0008] Compared with the prior art in which the judgment of the needle injection position depends on the work experience and subjective judgment of the experimenter, the present invention proposes an injection system, which can provide the experimenter with a graded judgment basis for the injection position based on the guide part provided by the system, thereby improving the injection efficiency of the experimenter.

[0009] In addition, on the one hand, there are differences in understanding among those skilled in the art; on the other hand, the applicant studied a large number of documents and patents when making the present invention, but due to space limitations, not all details and contents are listed in detail. However, this does not mean that the present invention does not have the characteristics of these prior arts. On the contrary, the present invention already has all the characteristics of the prior art, and the applicant reserves the right to add relevant prior art to the background technology. Summary of the invention

[0010] At present, stem cells are mainly used in clinical practice for trauma injury repair, facial repair, bone and joint injury repair and tumor suppression. Cutting-edge scientific research on stem cell transplantation has been carried out for several years and has achieved beneficial results.

[0011] The diameter of stem cells is between 10 and 20 μm, which is much larger than the molecular volume of ordinary injected drugs. There are many types of stem cells, and different types of stem cells are used for different diseases. For example, human bone marrow mesenchymal stem cells are used for targeted repair of osteoarthritis and injected into the joint cavity. Compared with intravenous injection of drugs, stem cells have higher requirements for injection operation and flow monitoring due to the special size and type of stem cells.

[0012] In view of the deficiencies of the prior art, the present invention provides an injection system, in particular, a system suitable for stem cell injection. The injection system comprises an injection device and a guide part capable of guiding the injection device to inject at the correct position and at the correct angle, the guide part comprises a detection unit, a control unit and an image guidance unit, when the detection unit detects that the injection device enters a preset first-level injectable area, the image guidance unit turns on the image guidance function; when the detection unit detects that the injection device enters a preset second-level injectable area, the image guidance unit generates a preset acupuncture position in the image provided under the image guidance function, wherein the first-level injectable area is larger than the second-level injectable area.

[0013] According to a preferred embodiment, the thickness of the blood vessels and the location of the blood vessels can become the classification criteria for the second-level injectable area. When the control center screens the blood vessels, the blood vessels with large diameters and located in the area where injection is convenient are the best. When the first-level injectable area is the triceps brachii, the control unit can select blood vessels in good condition based on the vascular distribution image of the patient's triceps brachii, and control the vascular imaging unit to display the vascular position of the area, and display the perspective image of the blood vessel at the actual position of the blood vessel in the patient's upper arm, thereby reducing the time for medical staff to find the blood vessels. Abandonment of a blood vessel means that the medical staff holds the needle and moves it from the blood vessel to other positions based on other factors (difficult to adjust the angle, etc.). When the blood vessel is abandoned, the control center will generate another blood vessel position. Preferably, the system can generate at least three colors of blood vessel images in the first-level injectable area based on the blood vessel status, and each color represents the priority of the blood vessel status.

[0014] Beneficial effects of this technical solution:

[0015] (1) In actual injection, the injection efficiency of medical staff often depends on their work experience and mentality, and it is very easy to have problems such as wrong injection site selection or wrong operation. On the one hand, such problems will cause cyanosis of the skin at the injection site of the patient and reduce the number of injection sites that can be selected; on the other hand, it will also cause tension between doctors and patients, leading to quarrels between medical staff and patients due to repeated injection issues. The injection device provided by the present invention can provide guidance to medical staff on the injectable area. Due to the assistance of the machine, patients can have more trust in novice medical staff, and medical staff can complete the injection with less energy.

[0016] (2) When performing an injection, the vascular imaging in the prior art mainly provides medical staff with a vascular image of a region, and the intricate large blood vessels and tiny capillaries will be displayed, which will cause visual illusions for medical staff. Even if the medical staff selects a suitable large blood vessel, it is possible to inject into the wrong position due to visual illusions. The vascular imaging technology using color as a priority guide provided in this application can provide medical staff with correct visual guidance and prevent them from being distracted by the complicated blood vessels.

[0017] According to a preferred embodiment, the detection unit comprises a thermal imaging unit and a visual acquisition unit, wherein the control unit overlaps the image captured by the visual acquisition unit and the image captured by the thermal imaging unit to confirm the primary injectable area of ​​the injection device.

[0018] According to a preferred embodiment, the detection unit further comprises a blood vessel development unit, wherein the control unit generates a second-level injectable area within the first-level injectable area in response to vein data within the first-level injectable area transmitted by the blood vessel development unit.

[0019] When stem cells are used for facial filling, the choice of injection sites on the face is limited due to the rich blood vessels on the face and the presence of facial features being blocked. In particular, when the face is filled, the facial morphology will change with the filling of stem cells. In order to meet the requirements of facial correction, medical staff are often required to perform stem cell injection and filling at multiple locations on the face. The injection operation will leave a short wound on the face. When wounds appear densely at a certain location on the face in a short period of time, it is easy to increase the risk of facial infection. The frequent insertion of dense needles into the same location on the face will stimulate and damage the epidermis, destroy the skin's self-protection barrier, and also cause subtle traumatic inflammation. Improper care can cause skin needle infection. However, in the prior art, when medical staff perform facial filling injections on users, they can often only choose the needle insertion location based on their own experience and simple black marking lines drawn on the face. In the field of medical aesthetics, facial filling based on stem cell injections requires multiple and intensive injections, and the volume of stem cells injected in each injection also needs to be evaluated in actual operations. Medical staff can only "feel" the injection based on experience and feedback on the injection effect, which can also lead to poor medical aesthetics results and facial adjustment effects that do not meet the user's expectations. Especially when the needle is inserted in the wrong position and the stem cells used for filling are injected into the facial arteries or small blood vessels, not only will the facial adjustment be ineffective, but the stem cells will also cause the user to suffer from acute symptoms such as embolism when they enter other parts of the body through the blood vessels.

[0020] Based on the adjustment parts divided by the medical staff terminal, the control unit can generate a second-level injectable area suitable for the current facial shape according to the patient's facial shape. For example, when the medical staff chooses to shape the nose, the image guidance unit will only project the second-level injectable area on the nose to show the blood vessels distributed in the nose, such as the aorta at the base of the nose.

[0021] During the injection process, the control unit can readjust and generate a second-level injectable area suitable for the current facial shape according to the changes in the patient's facial shape. Preferably, the control unit can transmit the regenerated second-level injectable area to the corresponding first-level injectable area on the face through the image guidance unit based on the release of the needle puncture state of the injection device.

[0022] After avoiding the problem of intravascular injection, different facial muscle tissues have different abilities to absorb stem cells. When the muscle tissue around the injection site selected by medical staff is difficult to quickly absorb stem cells, on the one hand, continued injection is difficult to achieve the desired effect of filling the face in that area, and may even deform the face in that area; on the other hand, when the absorption rate is much lower than the injection rate, stem cells will accumulate in the muscle tissue at that location and cannot be absorbed during the medical beauty process (the protrusions produced by the accumulation exist on the face for a few days or even several months), and cannot be found in the early stage by naked eye observation (the injection site is not suitable for touch due to the dense wounds). Since the flow rate of stem cells in human blood vessels or subcutaneous tissue is lower than that of the liquid medicine, even if the medical staff injects slowly, there is still a situation where the stem cells at that location cannot be absorbed in time. There are two possible situations where they cannot be absorbed in time. One is that the acupuncture position or angle is incorrect, resulting in the inability of the stem cells entering the location to flow or be evenly distributed to the connective tissue; the other is that the flow rate of the stem cells at that location is too slow, requiring a flow time several times lower than the injection speed.

[0023] According to a preferred embodiment, the visual acquisition unit includes a three-dimensional module, wherein the control unit can generate a three-dimensional image of the injected tissue based on the data acquired by the three-dimensional module to determine the height difference of the injection position during the injection process. By overlapping and comparing the three-dimensional images at different time periods during the injection process, the control unit can determine whether the injection position has a problem of stem cell aggregation under the skin.

[0024] When the convex height of the three-dimensional image of the face located in the second-level injectable area exceeds α, the control unit controls the image guidance unit to generate an image with a warning function at the abnormal convex position. On the one hand, the change of the image guidance unit provides an alarm for medical staff; on the other hand, the change of the image guidance unit can directly show the deformed facial morphology to medical staff, and medical staff can adjust the needle insertion position and angle in time to prevent excessive stacking of stem cells in the facial position during the facial filling process. Preferably, the fourth color of the image with a warning function generated at the abnormal convex position can be different from the three colors of the image used to guide medical staff to insert the needle.

[0025] During the injection process, based on the slower flow of stem cells in the subcutaneous blood vessels of the face or other organs, the height of the abnormal protrusion generated on the face or other organs may also exceed β. When the protrusion height exceeds β, the image guidance unit can generate a fifth different color. The control unit can keep the form of the image generated by the image guidance unit unchanged except for the color. The fifth color is used to prompt medical staff to slow down the injection speed or stop the injection but not remove the needle, so as to allow stem cells to flow into the human body from the blood vessels or provide buffer time for stem cells to flow subcutaneously. Preferably, α is greater than β.

[0026] When the abnormal protrusion generated by the face or other organs is reduced to γ, the control unit can control the image guidance unit to restore to providing the medical staff with an image for guiding the medical staff to insert the needle. Preferably, γ is smaller than β.

[0027] In the actual injection process, stem cell injections involve repeated injections or supplementary injections. The distribution of an individual's blood vessels is fixed and does not change. Based on this, the system can record an individual's injection situation and reduce the recommendation priority of locations with injection problems based on historical records. For example, when stem cells are used as facial filler materials, they usually disappear gradually with the body's metabolism after filling the face. If the body's metabolism is faster, the maintenance time will usually be shortened, which can last for about three days. If the metabolism is slower, the maintenance time may be extended, which can last for about 5 years. Therefore, for users who need to maintain their facial shape for a long time, multiple stem cell injections on the face are necessary.

[0028] The injection system can record all skin conditions of the user after injections, such as bulges, and based on the pre-stored structural model of facial blood vessels or other tissues, superimpose the existing detection records of injection conditions, and simulate and recommend the best injection point range for the next location. For example, there should be a location with faster absorption near the location with slow absorption. Locations that are not absorbed by stem cells in the past or locations within 1 cm in diameter of the location are no longer recommended as injection locations.

[0029] According to a preferred embodiment, based on the terminal confirmation of the medical staff, the control unit can retrieve the facial injection history data and / or facial structure model related to the user from the history database. When the control unit generates a three-dimensional image of the face based on the facial data collected by the visual acquisition unit, and when providing injection guidance to the medical staff, based on the facial position in the facial injection history data projected with the fourth color, the facial position is excluded from the determination result of the injectable area.

[0030] By retrieving the historical database, the system can obtain the user's past skin conditions and avoid the situation where the injection has occurred in a position where the stem cells could not be absorbed or homogenized. Referring to the historical database can reduce the number of invalid attempts of the injection system, reduce the accident rate, and avoid repeated invalid injections that cause damage to the skin. Medical beauty injection is a related process. The quality of an injection position is related to the selection of surrounding injection positions and the presentation of the final medical beauty effect. In the existing medical beauty injection process, the proportion of invalid groping injections is too high, which is not conducive to the rapid and accurate presentation of medical beauty effects. The injection system proposed in this application can combine historical data and the current user's facial state to present medical staff with selectable areas with good injection effects. By collecting the user's historical injection areas and historical problem injection areas, combined with the user's current non-vascular area, it is possible to screen safe injection areas for medical staff. At the same time, based on the monitoring of the user's facial state during the injection process, it can also warn the medical staff when they choose an inappropriate injection area, avoiding the medical staff from injecting a large number of stem cells at this location, resulting in the formation of a protrusion that is too conspicuous and cannot be absorbed by the face in a short time (such as the time during the medical beauty process). This system automatically assists the operator in analyzing the microinjection effect of each point according to the predetermined analysis method through the real-time high-precision automatic detection of ectopic sites during the injection process, and quickly transmits the data back to the display area. At the same time, it visualizes the results in a graded manner, so that the operator can very intuitively obtain the location of the injected points and the injection effect (displayed in color grading). Furthermore, it also uses preset physiological structure data (universal human facial physiological structure preset data or individual facial physiological structure pre-checked for the operated individual), combined with the performance detection and evaluation of the injected area, to automatically generate recommended injection areas, so that the operator can quickly find the better or optimal injection point that meets the expectations of medical beauty.

[0031] At the same time, the injection process is divided into three stages, including the first injection stage, the second injection stage and the third injection stage. When in the first injection stage, the injection needle has not yet entered the human body, and the medical staff holds the injection needle to find an injectable position and an injectable angle. When in the second injection stage, the medical staff holds the injection needle to allow the injection needle to enter the human body. When in the third injection stage, it is divided into three situations based on the three medical methods of injection, infusion and puncture. The third injection stage of the injection is that the medical staff pushes the needle by hand and pulls out the needle after the liquid is injected into the body. The third injection stage of the infusion is that after the medical staff fixes the position of the needle, the patient waits alone for the infusion process to end. The third injection stage of the puncture includes the drainage of the collected sample, that is, the stagnation of the puncture needle and the withdrawal of the puncture needle.

[0032] The system can also be used for monitoring intravenous injection. When the needle leaves the first-level injectable area or the second-level injectable area, the system can promptly send out an alarm and prompt to the medical staff or the patient.

[0033] According to a preferred embodiment, the system can also be provided with a third-level injectable area. When the needle enters the vein and stabilizes in the vein, the system can set the position contour as the third-level injectable area based on the position of the needle. When the system detects an error between the needle of the injection device and the third-level injectable area, the system can issue an alarm. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 is a cross-sectional schematic diagram of an injection device according to a preferred embodiment of the present invention;

[0035] Figure 2 is a schematic diagram of a first component of a preferred embodiment provided by the present invention;

[0036] Figure 3 is a schematic diagram of a second component of a preferred embodiment provided by the present invention;

[0037] Figure 4 It is a schematic diagram of the pipe body provided by the present invention being retracted into the wiring area;

[0038] Figure 5 It is an overall schematic diagram of a preferred embodiment provided by the present invention;

[0039] Figure 6 It is a structural schematic diagram of the visual acquisition unit provided by the present invention.

[0040] Reference numerals list

[0041] 100: first component; 110: wiring area; 120: coupling member; 130: retaining member; 131: recessed entrance; 140: partition member; 200: second component; 210: first needle body; 220: protruding member; 230: releasing portion; 240: tube body; 250: first protective member; 300: inserting member; 400: introducing member; 500: guiding element; 600: three-dimensional image sensor; 610: light source; 620: spectroscopic element; 630: camera; 640: light beam. DETAILED DESCRIPTION

[0042] The following is a detailed description with reference to the accompanying drawings.

[0043] In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front", "rear", etc. indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, which are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention. In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance. In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "provided with", "connected", etc. should be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be directly connected, or indirectly connected through an intermediate medium, or it can be a connection between the two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0044] Example 1

[0045] This embodiment provides a system for evaluating the status of stem cell injection based on a three-dimensional facial image. The system can scan the patient's face and compare the patient's changing face in real time to find out whether there is a problem of fat stem cell accumulation at the injection site, and provide medical staff with a basis for waiting for the fat stem cells to be homogenized under the skin or removing the needle to change the injection site based on the degree of fat stem cell accumulation.

[0046] The patient wishes to adjust the facial shape by injecting fat stem cells. The system can start working when the medical staff evaluates the patient's face and operates on the face.

[0047] The visual acquisition unit can perform a three-dimensional scan on the face of the injectee to obtain the three-dimensional point cloud and image data of the face. Preferably, the visual acquisition unit includes a three-dimensional scanner. The local descriptor method is used to extract the feature points of the facial features. For example, the feature points of the nose are the root of the nose, the bridge of the nose, the nasal septum, the tip of the nose and the wing of the nose. Preferably, the visual acquisition unit can include a high-precision three-dimensional scanner, such as the facial scanning system of FC BodyScan, to obtain high-precision facial information of the user through three-dimensional laser point cloud scanning technology.

[0048] The recipients hope to have their face filled with fat stem cells to adjust their facial shape.

[0049] When the injection starts, the control unit determines the first-level injectable area based on the initial setting of the medical staff. The first-level injectable area is the facial position that needs to be filled with fat stem cells after evaluation by the medical staff.

[0050] The control unit defines the second-level injectable area based on the blood vessel projection image provided by the visual acquisition unit, and controls the image guidance unit to project a green image to the corresponding position of the face, that is, the control unit excludes the blood vessel position and displays the blood vessel position in the projected green image for medical staff to perform adipose stem cell injection. Preferably, the visual acquisition unit includes an infrared blood vessel imaging component. The image guidance unit includes a projection component. The infrared blood vessel imaging component and the projection component together constitute an infrared blood vessel imager.

[0051] The control unit is capable of generating a new facial 3D image every second, and overlapping the newly generated facial 3D image with the facial 3D image closest to it in time, so as to confirm whether there is any bulge on the face of the second-level injectable area beyond the preset range.

[0052] Preferably, when the newly generated facial 3D image overlaps with the facial 3D image closest to it in time, the control unit can record the shape generated at the corresponding position of the newly generated facial 3D image that does not match the facial 3D image closest to it in time, and use the position corresponding to the shape in the facial 3D image closest to it in time as the base point to calibrate the distance from the base point to the highest point of the shape. This distance is the convex height.

[0053] When the height of the protrusion exceeds 2mm, the control unit controls the image guidance unit to generate a flashing yellow image at the abnormal protrusion position to prompt the medical staff to stop the injection without removing the needle. When the height of the protrusion is lower than 1mm, the image returns to normal and the medical staff can continue the injection. When the flashing yellow image lasts longer than the waiting time assessed by the medical staff, the medical staff can remove the needle by themselves. Based on the needle removal behavior captured by the visual image unit, the control unit controls the image guidance unit to generate a green image of the second-level injectable area again. At this time, the second-level injectable area does not include the circular area with a radius of 3mm centered on the lower needle position where the problem occurred last time.

[0054] Due to the difference in injection speed among medical staff, when the tissue at this facial position cannot absorb or homogenize the fat stem cells, the speed of bulge generation will increase and the height of the bulge will exceed 3mm within 1 second. When the bulge height exceeds 3mm, the control unit controls the image guidance unit to generate a flashing red image for 10 seconds, and turns off the projection of the second-level injectable area of ​​the image guidance unit after 10 seconds. Medical staff can restart the system based on terminal operation.

[0055] Example 2

[0056] This embodiment provides an injection device suitable for facial injection. The injection device provided in this embodiment is suitable for stem cell injection. The injection device provided by the present invention is suitable for injection into bone joint cavity. The injection device provided by the present invention is suitable for stem cell injection for cerebral hemorrhage. The injection device provided by the present invention can be used for injection into irregularly shaped organs of the human body.

[0057] The irregular organ can refer to a human ankle joint, head, face, femoral joint or other organ with a non-flat structure having a protrusion or an arc.

[0058] Based on the vascular image projected on the human body surface, the use of traditional handheld injections will block the vertical light on the one hand; on the other hand, because the blood vessels in the second-level injectable area are precise and narrow, when holding the syringe and inserting the needle directly, the medical staff may have problems such as hand shaking, and the injection position may deviate from the projected selected position. When performing stem cell filling, especially facial stem cell filling to adjust the facial shape, the choice of filling position has an important impact on the state of stem cells in the face and the adjusted facial shape. The wrong position selection will cause the facial adjustment to be inconsistent or even not meet the user's requirements, and will also cause the stem cells to be injected into the non-muscle gap by mistake, which can seriously lead to problems such as dermal infection.

[0059] The injection device provided in this embodiment can be roughly parallel to the human body surface. When selecting a position, the medical staff can translate the injection device sleeved on the bracket to the selected position and then stop, and wait for the medical staff to insert the needle after the medical staff is ready. During this period, the medical staff's hand can not always control the injection device in a holding posture. At the same time, the injection device of this embodiment adopts an external connection pipeline to provide stem cells to the needle. For the situation where multiple points are required for injection, especially the multi-point injection of facial adjustment, the injection volume of each point is uncertain. Before the injection, the medical staff cannot accurately estimate the specific volume of stem cell solution required for this facial filling to achieve the best effect. The prior art adopts a one-time injection method, and each syringe is filled with a fixed volume of stem cells, which not only causes the problem of waste in use, but also increases the cost of facial filling. On the one hand, the injection device can avoid the problem of contamination during the transmission process of the stem cell solution input through the pipeline; on the other hand, it can also enable medical staff to take it when needed and shut it down when not needed, without the problem of opening the syringe once and using the amount filled in the syringe and throwing away the excess.

[0060] The injection system includes an injection device. The injection device includes a first component 100 and a second component 200. The first component 100 is provided with a wiring area 110 for holding a tubular body having a certain length. The wiring area 110 is used to hold a portion of a tubular body 240 having a certain length. The tubular body 240 has a first end connected to the second component 200. The first component 100 also includes a retaining member 130 and an inserting member 300. The retaining member 130 is provided with a recessed entrance 131 facing the skin surface. The second component 200 is connected to the first component 100 in a detachable manner. The second component 200 includes a first needle body 210. The first needle body 210 is fluidically connected to the first end of the tubular body 240 so that the injection liquid disposed in the tubular body can flow out from the first needle body 210.

[0061] According to a preferred embodiment, the insert 300 is disposed in the recess 131 of the holder 130. The insert 300 can pivot relative to the first member 100 in the recess 131 of the holder 130.

[0062] The wiring area 110 is used to manage the tube body 240 of a certain length. The tube body 240 has a certain length. The tube body 240 is wound around the periphery of the injection device and stored in the wiring area 110 to avoid the tube body 240 from being tangled and twisted due to the certain length of the tube body 240. The retaining member 130 is provided with a recessed opening 131. When the injection device is connected to a certain part of the user's body, if the injection device moves on the user's skin, the recessed opening 131 provides sufficient space for the insert 300, so that the insert 300 can be prevented from being cut or folded.

[0063] Preferably, the second member 200 is provided with a protruding piece 220. The protruding piece 220 is provided with a rib.

[0064] The second component 200 includes a first guard 250. The first guard 250 is disposed above the first needle body 210. The recessed opening 131 is configured to be conical.

[0065] Preferably, the recess 131 contains a drug.

[0066] Preferably, the injection device is further provided with a tube body connector. The tube body connector has a specific length.

[0067] Preferably, the first member 100 is provided with a holding area for easy hand gripping. When the first member 100 and the second member 200 are connected or separated, the operator's hand is placed in the holding area to ensure the stability of the finger grip during the operation, so as to avoid the first member 100 or the second member 200 slipping due to unstable grip during the process of connecting or separating the first member 100 and the second member 200.

[0068] Preferably, the injection device is provided with a partition at least partially restrained within the first member 100 by the retaining member.

[0069] like Figure 1 and Figure 5 The injection device shown comprises a first component 100, a second component 200, a tubular body 240, a partition 140, a retainer 130, an insert 300 and an introducer 400. The second component 200 comprises a first needle 210, and when the second component 200 comes into contact with the first component 100, the first needle 210 is in fluid communication with the insert 300 by piercing the partition 140. Preferably, the injection device is further provided with a guide element 500 for guiding the introducer 400. The guide element 500 is arranged in a funnel shape.

[0070] Preferably, the second component 200 further includes a first protective member. The first protective member can reduce the risk of an operator or user being stabbed by the first needle 210 when using the injection device, and at the same time, the first protective member can reduce the risk of the first needle 210 being contaminated. If the first needle 210 is contaminated, the circulating liquid will also be contaminated, affecting the health of the user.

[0071] Preferably, the separator 140, the retainer 130, the introducer 400 and the guide element 500 are arranged in the first member 100 in a press-fit manner. Preferably, the retainer 130 is press-fitted into the first member 100. Preferably, the retainer 130 can be connected to the first member 100 by welding. Preferably, the retainer 130 is arranged in the first member 100 through the protrusion 220. Preferably, the retainer 130 can be used for other adapted devices. Preferably, the retainer 130 is made of the same material as the insert 300 and can be attached by thermal bonding, welding or other means. Preferably, the retainer 130 is made of the same material as the insert 300 and is made into a single component. Preferably, the retainer 130 includes a guide element 500, which can guide the introducer 400 through the separator 140 and into the insert 300. Preferably, the guide element 500 can be of any reasonable shape and size. Preferably, the guide element 500 and the holder 130 can be made of different materials. Preferably, the insert 300 can be press-fitted into the holder 130, and the guide element 500 can be press-fitted into the holder 130, so as to simplify the manufacturing process and reduce the cost.

[0072] The first member 100 is provided with a wiring area 110 for holding a tube body 240 having a certain length, such as Figure 2 and Figure 4 The wiring area 110 is used to manage a tube body 240 of a certain length. The tube body 240 has a certain length. The tube body 240 is wound around the injection device and put into the wiring area 110. When the tube body 240 is pulled in a certain direction, the tube body 240 of a certain length is put into the wiring area 110, so that the occurrence of the tube body 240 being twisted can be reduced; if the tube body 240 is not put into the wiring area 110, when the tube body 240 is pulled in a certain direction, the tube body 240 through which the liquid flows is prone to be twisted, and the internal space of the tube body 240 is squeezed, resulting in blockage inside the tube body 240, so that the liquid therein cannot flow.

[0073] Preferably, a wiring area 110 is provided on the second member 200. Preferably, both the first member 100 and the second member 200 are provided with a wiring area 110.

[0074] Preferably, the tube 240 having a certain length can be clamped or otherwise restrained by being wrapped around the injection device. Preferably, the routing area 110 is arranged at any reasonable direction of the injection device. When the tube 240 is wrapped around the injection device and held in the routing area 110, the tube 240 having a certain length will not be kinked. In addition, the tube 240 can be changed in direction by wrapping around the injection device. Preferably, the tube 240 can travel under the injection device to change direction.

[0075] like Figure 1 As shown, the holder 130 of the first member 100 is provided with a recessed opening 131. Preferably, the recessed opening 131 is set to a conical shape that can provide enough space for the insert 300, and the insert 300 can move relative to the first member 100 when the position of the first member 100 on the surface of the user's skin changes. Preferably, the recessed opening 131 can be set to any reasonable shape, for example, the recessed opening 131 can be circular. Preferably, the recessed opening 131 can be set to any reasonable size. If the holder 130 is not provided with the recessed opening 131, when the injection device is connected to a certain part of the user's body and the injection device moves on the user's body skin, the insert 300 may be cut and folded because there is no margin space around the insert 300. The recessed opening 131 provided on the holder 130 can provide enough space around the insert 300 so that the pivot point of the insert 300 is away from the user's skin. When the injection device is connected to a part of the user's body, if the injection device moves on the user's skin, the arrangement of the recessed opening 131 provides sufficient space for the inserting member 300, thereby preventing the inserting member 300 from being cut or folded.

[0076] Preferably, the insert 300 is configured as a conical structure. Preferably, the insert 300 can be configured as other reasonable shapes, for example, the insert 300 can be configured as a funnel shape. Preferably, the insert 300 can be attached to the holder 130 .

[0077] The second component 200 is connected to the first component 100 in a detachable manner. Figure 2-3As shown, the second member 200 is provided with a protruding piece 220, and the protruding piece 220 is provided with a rib. The first member 100 is provided with a coupling piece 120 for receiving the protruding piece 220. Preferably, the protruding piece 220 can be engaged or locked with the coupling piece in a sliding manner. Under the condition that the protruding piece 220 and the coupling piece are engaged or locked, the second member 200 is combined or interfered with the first member 100. The second member 200 is also provided with a release portion 230 that can release the combined state or the adapted state of the first member 100 and the second member 200. Preferably, the release portion 230 is provided on the second member 200 corresponding to the protruding piece 220. When the first member 100 and the second member 200 are combined or interference fit, the release portion 230 is pressed toward each other to release the protruding member 220 from the engaging member 120, thereby releasing the engaging or locking state of the protruding member 220 and the engaging member, thereby separating the first member 100 and the second member 200. When the first member 100 and the second member 200 are in combination or interference fit, if the release portion 230 is not pressed toward each other, the protruding member 220 and the engaging member 120 will continue to maintain the engaging or locking state, so that the first member 100 and the second member 200 remain in the combined or adapted state.

[0078] Preferably, the release portion 230 is provided with a textured surface to facilitate pressing or grasping by hand. Preferably, at least one release portion 230 is provided on the second member 200 .

[0079] Preferably, the rib on the protruding piece 220 is configured to be protruding or recessed relative to the surface of the second member 200. Preferably, at least one rib is provided on the second member 200.

[0080] The second member 200 is connected to the first member 100 in a detachable manner. When the protruding piece 220 on the second member 200 slides into the engaging piece 120 of the first member 100 and reaches a snap-on or locked position, the second member 200 is combined or interfered with the first member 100. The process of combining the second member 200 with the first member 100 enables the first needle 210 to pierce the partition 140 of the first member 100, so that the first needle 210 is in fluid communication with the insert 300, and the first needle 210 is in fluid communication with the first end of the tube 240. When the second end of the tube 240 is connected to a fluid source, the fluid source can be an infusion pump and a reservoir therein, the first needle 210 is in fluid communication with the tube 240, and the first needle 210 is in fluid communication with the insert 300, so that the liquid in the fluid source flows out through the tube 240 and can flow through the insert 300 into the user's body.

[0081] The first member 100 is provided with a holding area for easy hand gripping. Preferably, the holding area can be set as a recessed portion on the first member 100. When the first member 100 and the second member 200 are connected or separated, the operator's hand is placed in the holding area to ensure the stability of the finger grip during the operation, to prevent the operator from slipping off the first member 100 or the second member 200 due to unstable grip during the process of connecting or separating the first member 100 and the second member 200, and the setting of the holding area enables the operator to better apply force to the first member 100. Preferably, the rear edge of the first member 100 is recessed inward to form a holding area for hand gripping.

[0082] Preferably, the first component 100 is provided with an adhesive layer capable of maintaining the first component 100 on the skin surface on the bottom surface in contact with the skin. Preferably, a covering layer is provided on the adhesive layer. Before the first component 100 is adhered to the patient's skin, the covering layer can protect the adhesive layer to prevent the adhesive layer from being exposed to the outside world and adhering to impurities before contacting the skin, thereby rendering the adhesive layer ineffective. When using the first component 100, the covering layer can be removed from the adhesive layer to expose the adhesive layer, and the bottom surface of the first component 100 is facing the user's skin and the first component 100 is pressed, so that the first component 100 can be firmly maintained on the skin. Preferably, the covering layer on the adhesive layer can be paper or other elements. Preferably, the first component 100 is not provided with an adhesive layer on the bottom surface in contact with the skin.

[0083] The second component 200 includes at least a first needle body 210 and a tubular body 240. Preferably, the first needle body 210 is arranged in a curved shape. The first needle body 210 is configured in a curved shape that enables the first needle body 210 to rotate. When the second component 200 is combined with the first component 100, the tubular body 240 is in fluid communication with the insert 300. Preferably, the injection device is provided with a funnel-shaped guide element 500 to guide the introduction needle.

[0084] Preferably, the second member 200 is disposed on the top of the first member 100. When the first member 100 and the second member 200 are in interference fit, the first needle 210 is located in the middle of the partition 140, and the first needle 210 pierces the partition 140 of the first member 100 so that the first member 100 and the second member 200 are in a sealed state. Since the first needle 210 is in a curved shape, the first needle 210 can maintain the sealed state of the first member 100 and the second member 200 when rotating to prevent leakage when liquid flows.

[0085] According to a preferred embodiment, the injection device comprises a first component 100 and a second component 200. The second component 200 is connected to the first component 100. The second component 200 comprises a tubular body 240. Preferably, the tubular body 240 can extend from the insert 300 at any reasonable angle. Preferably, a shorter tubular body 240 can be used in conjunction with the injection device. Preferably, the recessed opening 131 of the retaining member 130 may include a drug, which may be a nutritional, antibacterial or other type of drug. For example, an antibacterial drug is provided in the recessed opening 131. When the injection device is attached to the user's skin and inserted into the body, the antibacterial drug in the recessed opening 131 can be attached to the insertion site, which can reduce the probability of infection.

[0086] According to a preferred embodiment, the injection device includes an introduction member 400. Preferably, the introduction member 400 can be arranged in an arc shape, a "V" shape or any reasonable shape. For example, the introduction member 400 can be arranged in a half-moon shape. Preferably, the introduction member 400 is arranged in a "C" shape in a manner that can surround the outside of the insert 300. The insert 300 is arranged inside the introduction member 400 so that the introduction member 400 can protect the insert 300. Preferably, the introduction member 400 can completely surround the insert 300. Preferably, the introduction member 400 does not completely surround the insert 300. The introduction member 400 extends through the insert 300 and through the user's skin. For example, when the introduction member 400 is in a "C" shape, after the insert 300 is inserted into the user's skin, the introduction member 400 can be separated from the insert 300 in a sliding manner and will not drive the insert 300 to move from the user's body. If the introduction member 400 is disposed inside the insertion member 300, the insertion member 300 may be pulled out of the user's body when the introduction member 400 is removed. Preferably, the tip of the introduction member 400 has a certain angle. The setting of the tip angle can help pull the introduction member 400 out of the insertion member 300 after the insertion of the insertion member 300.

[0087] Example 3

[0088] The method for accurately identifying the height of protrusions on the face or other skin surfaces involved in the present invention can be a dot matrix method obtained based on a three-dimensional image sensor.

[0089] The three-dimensional module of the visual acquisition unit acquires images and recognizes the user's face or other skin tissue. The three-dimensional module can include a three-dimensional acquisition device, which can also be a three-dimensional image sensor 600 set based on a dot matrix acquisition method.

[0090] like Figure 6As shown, the three-dimensional image sensor 600 includes a light source 610, a beam splitter 620 and a camera 630. Light (e.g., infrared light and / or visible light) may be emitted by the light source 610. During operation, the light source 610 may emit one or more light beams toward the user's face or other skin parts. The beam splitter 620 may split these light beams into additional light beams 640. The camera 630 includes a digital image sensor that is sensitive to the wavelength of light associated with the light beam 640 (the additional light beam 640 can be infrared light of 900 to 1000 nm or other suitable wavelengths), so that the camera 630 captures an infrared image or a visible image of the user's face or other skin parts, while the user's face or other skin parts are covered by the array of points generated by irradiating the user's face or other skin parts with the light beam 640, thereby generating a three-dimensional mapping of the user's face or other skin parts, i.e., a three-dimensional image. Preferably, the three-dimensional image can refer to a three-dimensional image of the patient's face. The three-dimensional image can refer to a three-dimensional image of the patient's nose.

[0091] According to a preferred embodiment, the number of light beams 640 irradiating the user's face or other skin areas may be at least 100, at least 500, at least 2000, at least 10000, at least 25000, at least 50000, less than 1,000000, less than 300000, less than 100000 or less than 75000.

[0092] According to a preferred embodiment, the light source 610 may be a single laser, an array of vertical cavity surface emitting lasers or other laser diodes, one or more light emitting diodes, or other light sources.

[0093] It should be noted that the above-mentioned specific embodiments are exemplary, and those skilled in the art can come up with various solutions inspired by the disclosure of the present invention, and these solutions also belong to the disclosure scope of the present invention and fall within the protection scope of the present invention. Those skilled in the art should understand that the present invention specification and its drawings are illustrative and do not constitute a limitation of the claims. The scope of protection of the present invention is defined by the claims and their equivalents. The present invention specification contains multiple inventive concepts, such as "preferably", "according to a preferred embodiment" or "optionally", all of which indicate that the corresponding paragraph discloses an independent concept, and the applicant reserves the right to file a divisional application based on each inventive concept. Throughout the text, the feature guided by "preferably" is only an optional method and should not be understood as a must-have setting. Therefore, the applicant reserves the right to abandon or delete the relevant preferred features at any time.

Claims

1. A stem cell injection system for facial filling, characterized in that: It comprises an injection device and a guide unit capable of guiding the injection device to inject at a correct position and a correct angle, wherein the guide unit comprises a detection unit equipped with a visual acquisition unit, a control unit and an image guidance unit. When the detection unit detects that the injection device enters the preset first-level injectable area of ​​the facial position that needs to be filled with adipose stem cells, the image guidance unit turns on the image guidance function, and the control unit defines the second-level injectable area based on the blood vessel projection image provided by the visual acquisition unit, and controls the image guidance unit to project the image to the corresponding position of the face; when the detection unit detects that the injection device enters the preset second-level injectable area, the image guidance unit generates a preset acupuncture position in the image provided under the image guidance function, wherein, The first level injectable area is larger than the second level injectable area. The visual acquisition unit includes a three-dimensional module, wherein the control unit can generate a stereoscopic image of the injected tissue based on data collected by the three-dimensional module, and the control unit can generate a new facial three-dimensional image every second. When the newly generated facial three-dimensional image coincides with the facial three-dimensional image that is closest to it in time, the control unit can record the shape generated at the corresponding position of the newly generated facial three-dimensional image that does not match the facial three-dimensional image that is closest to it in time, and use the position corresponding to the shape in the facial three-dimensional image that is closest to it in time as the base point, calibrate the distance from the base point to the highest point of the shape, so as to determine the protruding height difference of the injection position during the injection process, and the control unit controls the image guiding unit to generate a warning image at the abnormal protruding position.

2. The system according to claim 1, characterized in that The detection unit includes a thermal imaging unit, wherein the control unit overlaps the image captured by the visual acquisition unit and the image captured by the thermal imaging unit to confirm the primary injectable area of ​​the injection device.

3. The system according to claim 2, characterized in that Based on the adjustment parts divided by the medical staff terminal, the control unit can generate a second-level injectable area suitable for the current facial shape according to the patient's facial shape.

4. The system according to claim 3, characterized in that The control unit can readjust and generate a second-level injectable area suitable for the current facial morphology according to changes in the patient's facial morphology, wherein the control unit can project the regenerated second-level injectable area into the corresponding first-level injectable area on the face through the image guidance unit based on the release of the needle state of the injection device.

5. The system according to claim 4, characterized in that The injection device comprises a first component (100) and a second component (200), wherein the second component (200) is connected to the first component (100) in a detachable manner, wherein the second component (200) comprises a first needle body (210), and the first needle body (210) is fluidically connected to a first end of a tube body (240) so that an injection liquid disposed in the tube body (240) can flow out of the first needle body (210).

6. The system according to claim 5, characterized in that The first component (100) also includes a retaining member (130) and an inserting member (300), wherein the retaining member (130) is provided with a recessed opening (131) facing the skin surface, wherein the inserting member (300) is arranged in the recessed opening (131) of the retaining member (130) in such a manner that it can pivot relative to the first component (100) in the recessed opening (131) of the retaining member (130).

7. The system according to claim 6, characterized in that The recessed opening (131) is configured to have a conical shape capable of providing sufficient space for the insert (300), so that the insert (300) can move relative to the first member (100) when the position of the first member (100) on the user's skin surface changes.

8. The system according to claim 7, characterized in that The second member (200) is also provided with a releasing portion (230) capable of releasing the first member (100) and the second member (200) from a combined state or an adapted state.

Images