Composition with whitening effect containing peony extract and preparation method thereof
By using peony extract and multiple plant extract compositions in skin care products, and using frozen -drying process preparation, the problem of loss of natural activity ingredients and reduced safety in existing skin care products, realizing whitening, safety, and delaying the skin of the skin The effect of aging.
Patent Information
- Application Number
- CN202310602676.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-05-26
- Publication Date
- 2025-01-28
- Estimated Expiration
- 2043-05-26
AI Technical Summary
The existing skin care products containing peony extract on the market are inactivated due to the use of high-temperature and high-pressure homogenization process, and the product's efficacy is greatly reduced. At the same time, the product's safety is reduced due to the addition of a large number of artificial thickeners and tackifiers.
Compositions containing peony extracts and multiple plant extract compositions, and preparing through frozen -drying process to avoid high temperature operations, retain natural active ingredients, and increase the viscosity of products through natural ingredients to reduce artificial thickened and adhesives Dependence.
Effectively retain the whitening effect of peony extract, enhance the safety and use effect of the product, and delay skin aging and maintain the vitality of skin cells.
Smart Images

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Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of preparation of skin care products, and particularly relates to a composition containing peony extract and having whitening effect and a preparation method thereof. Background Art
[0002] Melanin is a special amino acid derivative present in the basal layer of everyone's skin. Long-term exposure to ultraviolet rays will cause melanin to change and generate a substance that protects the skin. Melanin then moves through layers of cell metabolism to reach the epidermis of the skin, causing skin problems such as spots and uneven skin tone that people see. Seeking the secret recipe for skin whitening has always been a goal that people have been pursuing.
[0003] Peony flowers are rich in amino acids, trace elements, flavonoids and other biologically active ingredients; and the peony seed oil extracted from peony seeds is also rich in unsaturated fatty acids such as gallic acid and oleanolic acid, as well as rare natural active ingredients such as squalene, sterols, vitamin E, etc., and has extremely high medicinal, edible and skin care value.
[0004] At present, there are endless cosmetics and skin care products containing peony extracts on the market, but there are also prominent problems: since the content of the main functional ingredients in skin care products is very small, in order to adjust the dosage form of the product, such products add a large amount of artificially synthesized thickeners, tackifiers, etc. to improve the viscosity and consistency of the product, which reduces the safety of the product.
[0005] In addition, most products on the market are currently produced using high-temperature and high-pressure homogenization methods. High temperatures are fatal to natural plants and can easily cause the inactivation of active ingredients in extracts added to skin care products, thereby greatly reducing the effectiveness of the products. Summary of the invention
[0006] In order to solve the above technical problems, the present invention provides a composition containing peony extract and having whitening effect and a preparation method thereof.
[0007] The composition containing peony extract and having whitening effect provided by the present invention comprises peony extract and a multiple plant extract composition.
[0008] The peony extracts mentioned above are: peony fresh petal squeezed liquid (PAEONIA SUFFRUTICOSA FLOWERWATER) and peony seed oil (PAEONIA SUFFRUTICOSA SEED OIL).
[0009] Among them, the peony fresh petal essence is made from original high-quality peony flowers and is prepared by a physical cold-pressing process. To be precise, it is the cell fluid of fresh peony petals. No exogenous water is added to it, which can maximize the retention of the natural active ingredients in the peony flower essence. Compared with rose flower hydrosol, the ability of peony flower essence to scavenge DPPH free radicals and hydroxyl free radicals is 10 times that of the latter.
[0010] Peony seed oil, especially the easily absorbed small molecule oil without solvent residue, obtained through supercritical carbon dioxide extraction technology, is specially used as a cosmetic raw material. It contains more than 90% unsaturated fatty acids, which can effectively remove various free radicals produced by cell metabolism, while combining and dissolving deposited lipid substances to maintain the vitality of skin cells.
[0011] The multiple plant extract composition comprises: golden chamomile extract, honeysuckle flower extract, notoginseng root extract, eucommia bark extract, glycyrrhiza glabra root extract and glycyrrhiza flavonoids compound.
[0012] The composition of the present invention further comprises the following components: 3-O-ethyl ascorbic acid, niacinamide, PEG-20 methyl glucose sesquistearate, tocopherol acetate, low molecular weight hyaluronic acid, inositol and glycerin.
[0013] The composition with whitening effect containing peony extract provided by the present invention comprises the following components in parts by weight:
[0014] 0.6-6 parts of peony extract, 0.05-4.1 parts of multiple plant extract composition, 0.1-1 parts of 3-O-ethyl ascorbic acid, 0.5-5 parts of niacinamide, 0.1-1 parts of PEG-20 methyl glucose sesquistearate, 0.1-1 parts of tocopherol acetate, 0.05-0.5 parts of low molecular weight hyaluronic acid, 0.5-3 parts of inositol, and 2-8 parts of glycerin.
[0015] Preferably, the peony extract described above comprises 0.5-5 parts of peony petal squeezed liquid and 0.1-1 parts of peony seed oil.
[0016] Preferably, the multiple plant extract composition comprises 0.01-1 part of golden chamomile extract, 0.01-1 part of honeysuckle extract, 0.01-1 part of Panax notoginseng root extract, 0.01-1 part of Eucommia bark extract, 0.01-1 part of Glycyrrhiza glabra root extract and 0.01-0.1 part of glycyrrhiza glabra flavonoids complex.
[0017] Preferably, in the compound of Glycyrrhiza glabra root extract and Glycyrrhiza flavonoids, Glycyrrhiza glabra root extract accounts for 92% and Glycyrrhiza flavonoids accounts for 8%.
[0018] More preferably, in the composition provided by the present invention, the weight proportions of the components are:
[0019] 3 parts of peony fresh petal squeezed stock solution, 0.5 parts of peony seed oil, 0.05 parts of golden chamomile extract, 0.01 parts of honeysuckle extract, 0.01 parts of Panax notoginseng root extract, 0.05 parts of Eucommia bark extract, 0.02 parts of Glycyrrhiza glabra root extract and glycyrrhiza flavonoids complex, 0.5 parts of 3-O-ethyl ascorbic acid, 3 parts of niacinamide, 0.5 parts of PEG-20 methyl glucose sesquistearate, 0.5 parts of tocopheryl acetate, 0.1 parts of low molecular weight hyaluronic acid, 1 part of inositol, and 4 parts of glycerin.
[0020] The various raw material components involved in the present invention have the following characteristics:
[0021] 3-O-ethyl ascorbic acid ether is a derivative of vitamin C. It can easily pass through the stratum corneum into the dermis. After entering the body, 3-O-ethyl ascorbic acid ether can inhibit the formation of tyrosinase, thereby inhibiting the production of melanin, exerting the biological efficacy of vitamin C, and achieving the effect of whitening and removing spots.
[0022] Golden chamomile, known as "noble flower" in Latin, has been regarded as a "magic flower" since ancient times. It is rich in flavonoids, which are effective in soothing, repairing sensitive skin, reducing fine red blood streaks, reducing redness, adjusting uneven skin tone, and has a good soothing effect on itchy skin.
[0023] Eucommia bark is rich in eucommia gum, which can bring natural viscosity, avoiding the occurrence of skin sensitivity problems caused by adding artificial thickeners and other ingredients to cosmetics to increase product viscosity, and can improve product safety.
[0024] The roots, rhizomes and other tissue cells of Glycyrrhiza glabra contain functional ingredients with strong antioxidant activity for skin depigmentation and lightening of spots, namely, glabrene and glabridine, which are applied to the whitening skin care composition of the present invention and can cooperate with peony extract to achieve good sunscreen and whitening effects.
[0025] The composition containing peony extract and having whitening effect provided by the present invention is obtained through freeze-drying process.
[0026] The composition with whitening effect containing peony extract provided by the present invention is prepared by the following method:
[0027] (1) Add the peony petals squeezed stock solution, peony seed oil, tocopherol acetate and glycerol in the formula amount into a container, stir evenly, record as solution I, and set aside;
[0028] (2) Add deionized water, niacinamide, golden chamomile extract, honeysuckle extract, Panax notoginseng root extract, and Eucommia bark extract to another container, stir evenly, and record it as solution II for later use;
[0029] (3) Take 10%-15% of the total amount of Solution II and add it to Solution I. Stir for 4-5 minutes until the solution becomes clear and transparent. Then add the remaining Solution II and stir evenly. Set aside.
[0030] (4) adding the root extract of Glycyrrhiza glabra and the glycyrrhiza flavonoids compound, 3-O-ethyl ascorbic acid, PEG-20 methyl glucose sesquistearate, low molecular weight hyaluronic acid, and inositol to the solution obtained in step (3), stirring evenly, and recording as solution III;
[0031] (5) placing solution III into a freeze drying chamber and starting freeze drying to obtain a composition;
[0032] The freeze-drying parameters are as follows: pre-freezing temperature is -60 to -40°C, and after reaching the specified pre-freezing temperature, it is maintained for 3 to 5 hours; drying time is 6 to 10 hours, the partition temperature in the sublimation stage is 30 to 50°C, and the pressure is 10 to 20Pa.
[0033] The freeze-dried composition provided by the present invention can be used alone, or compounded into a skin care product at an addition amount of 10%-20%. The dosage form of the skin care product can be any one of ointment, cream, lotion, liquid, essence, and mask.
[0034] The beneficial effects of the present invention are:
[0035] (1) The composition with whitening effect containing peony extract provided by the present invention is prepared by combining peony extract with 3-O-ethyl ascorbic acid, tocopherol acetate and niacinamide as main whitening effect substances. On the one hand, the property of tocopherol acetate being oxidized by light is utilized to block direct contact between skin surface cells and light, thereby reducing the damage of ultraviolet rays to the skin. On the other hand, with the help of the antioxidant and whitening effects of peony extract, combined with 3-O-ethyl ascorbic acid, tocopherol acetate and the like, the activity of tyrosinase in cells is inhibited by penetrating deeply into the skin, thereby fundamentally reducing the production of melanin, and finally achieving the skin whitening effect.
[0036] (2) The composition of the present invention also contains a variety of natural plant extracts and low-molecular hyaluronic acid and other ingredients. Each plant extract is rich in flavonoids and flavonoids, which can not only whiten the skin but also assist in proper hydration, which is beneficial for keeping the skin firm and hydrated, thereby delaying skin aging.
[0037] In addition, the inositol added in the present invention is a growth factor of animals and microorganisms. The addition of inositol can synergistically work with multiple natural plant extracts to further improve the vitality of skin cells.
[0038] (3) In the present invention, a small amount of Eucommia bark extract is added to increase the viscosity of the composition product using the natural eucommia gum component contained in the Eucommia bark. No additional synthetic thickeners, tackifiers and other components are added to the composition, thereby reducing the production cost of the composition product and improving the safety of the product.
[0039] (4) The peony extract used in the composition of the present invention is peony flower liquid and small molecule peony seed oil that is easily absorbed by the skin; wherein the peony flower liquid is made from original high-quality peony flowers and is prepared by a physical cold pressing process; the peony seed oil is obtained by supercritical carbon dioxide extraction technology, has no solvent residue, has a high safety factor, is rich in biologically active substances, and contains more than 90% unsaturated fatty acids, which can penetrate deeply into the skin and effectively remove various free radicals generated by skin cell metabolism, while combining and dissolving deposited lipid substances to maintain the vitality of skin cells.
[0040] (5) The present invention adopts a unique freeze-drying process to prepare the whitening composition, which avoids the destruction of natural extract components by high-temperature operation in the traditional cosmetic preparation process, can maximize the efficacy of the bioactive substances in the extract, and further enhance the overall efficacy of the composition product. DETAILED DESCRIPTION
[0041] In order to enable those skilled in the art to better understand the present invention, the present invention is further described in conjunction with specific implementation methods.
[0042] The peony seed oil used in the embodiments of the present invention is purchased from Heze Paine Biotechnology Co., Ltd., the capital of peony, and has an unsaturated fatty acid content of 92.05%.
[0043] Example 1
[0044] Add 3 parts of peony petal squeezed stock solution, 0.5 parts of peony seed oil, 0.5 parts of tocopherol acetate, and 4 parts of glycerol into a container and stir evenly, record it as solution I, and set aside;
[0045] (2) In another container, add deionized water, 3 parts of niacinamide, 0.05 parts of golden chamomile extract, 0.01 parts of honeysuckle extract, 0.01 parts of Panax notoginseng root extract, and 0.05 parts of Eucommia bark extract, stir well, and record as solution II for later use;
[0046] (3) Take 13% of the total amount of Solution II and add it to Solution I. Stir for 4 min until the solution becomes clear and transparent. Then add the remaining Solution II and stir evenly. Set aside.
[0047] (4) Add 0.02 parts of Glycyrrhiza glabra root extract and glycyrrhiza flavonoids complex, 0.5 parts of 3-O-ethyl ascorbic acid, 0.5 parts of PEG-20 methyl glucose sesquistearate, 0.1 parts of low molecular weight hyaluronic acid, and 1 part of inositol to the solution obtained in step (3), stir well, and record as solution III;
[0048] (5) placing solution III into a freeze drying chamber and starting freeze drying to obtain a composition;
[0049] The freeze-drying parameters are as follows: pre-freezing temperature is -50°C, and after reaching the specified pre-freezing temperature, it is maintained for 4 hours; drying time is 8 hours, the partition temperature in the sublimation stage is 40°C, and the pressure is 15Pa.
[0050] Example 2
[0051] Add 0.5 parts of peony petal squeezed stock solution, 0.1 parts of peony seed oil, 0.1 parts of tocopherol acetate, and 2 parts of glycerol into a container, stir evenly, record as solution I, and set aside;
[0052] (2) In another container, add deionized water, 0.5 parts of niacinamide, 0.01 parts of golden chamomile extract, 0.01 parts of honeysuckle extract, 0.01 parts of Panax notoginseng root extract, and 0.01 parts of Eucommia bark extract, stir well, and record as solution II for later use;
[0053] (3) Take 10% of the total amount of solution II and add it to solution I. Stir for 4 min until the solution becomes clear and transparent. Then add the remaining solution II and stir evenly. Set aside.
[0054] (4) Add 0.01 parts of Glycyrrhiza glabra root extract and glycyrrhiza flavonoids complex, 0.1 parts of 3-O-ethyl ascorbic acid, 0.1 parts of PEG-20 methyl glucose sesquistearate, 0.05 parts of low molecular weight hyaluronic acid, and 0.5 parts of inositol to the solution obtained in step (3), stir well, and record as solution III;
[0055] (5) placing solution III into a freeze drying chamber and starting freeze drying to obtain a composition;
[0056] The freeze-drying parameters are as follows: pre-freezing temperature is -40°C, and after reaching the specified pre-freezing temperature, it is maintained for 3 hours; drying time is 6 hours, the partition temperature in the sublimation stage is 30°C, and the pressure is 10Pa.
[0057] Example 3
[0058] Add 5 parts of peony petal squeezed stock solution, 1 part of peony seed oil, 1 part of tocopherol acetate, and 8 parts of glycerol into a container, stir evenly, record as solution I, and set aside;
[0059] (2) In another container, add deionized water, 5 parts of niacinamide, 1 part of golden chamomile extract, 1 part of honeysuckle flower extract, 1 part of Panax notoginseng root extract, and 1 part of Eucommia bark extract, stir well, and record as solution II for later use;
[0060] (3) Take 15% of the total amount of solution II and add it to solution I. Stir for 4 min until the solution becomes clear and transparent. Then add the remaining solution II and stir evenly. Set aside.
[0061] (4) Add 0.1 parts of Glycyrrhiza glabra root extract and glycyrrhiza flavonoids complex, 1 part of 3-O-ethyl ascorbic acid, 1 part of PEG-20 methyl glucose sesquistearate, 0.5 parts of low molecular weight hyaluronic acid, and 3 parts of inositol to the solution obtained in step (3), stir well, and record as solution III;
[0062] (5) placing solution III into a freeze drying chamber and starting freeze drying to obtain a composition;
[0063] The freeze-drying parameters are as follows: pre-freezing temperature is -60°C, and after reaching the specified pre-freezing temperature, it is maintained for 5 hours; drying time is 10 hours, the partition temperature in the sublimation stage is 50°C, and the pressure is 20Pa.
[0064] Example 4
[0065] The weight fractions of each component and the preparation steps are the same as those in Example 1, except that only the freeze-drying process parameters of the composition are changed;
[0066] The specific freeze-drying process parameters are: pre-freezing temperature is -40°C, and after reaching the specified pre-freezing temperature, it is maintained for 3 hours; drying time is 6 hours, the partition temperature in the sublimation stage is 30°C, and the pressure is 10Pa.
[0067] Example 5
[0068] The weight fractions of each component and the preparation steps are the same as those in Example 1, except that only the freeze-drying process parameters of the composition are changed;
[0069] The specific freeze-drying process parameters are: pre-freezing temperature is -60°C, and after reaching the specified pre-freezing temperature, it is maintained for 5 hours; drying time is 10 hours, the partition temperature in the sublimation stage is 50°C, and the pressure is 20Pa.
[0070] Example 6
[0071] The weight fractions of each component and the preparation steps are the same as those in Example 1, except that only the freeze-drying process parameters of the composition are changed;
[0072] The specific freeze-drying process parameters are: pre-freezing temperature is -45°C, and after reaching the specified pre-freezing temperature, it is maintained for 5 hours; drying time is 8 hours, the partition temperature in the sublimation stage is 42°C, and the pressure is 18Pa.
[0073] Examples 7-12
[0074] The freeze-drying process conditions of the composition product are the same as those of Example 1, except that only the weight fractions of the components in the composition are changed. The weight fractions of the components in the composition raw materials are specifically shown in the following table:
[0075] Table 1 Weight percentage of each component in Examples 7-12
[0076]
[0077]
[0078] The product performance of Examples 1-12 is shown in Table 2.
[0079] Table 2 Product performance of Examples 1-12
[0080]
[0081]
[0082] It can be seen from the above table that the product obtained in each embodiment has a better texture, a mellow and non-pungent peony fragrance, good adhesion to the skin, good air permeability, no allergic abnormalities after use, and has a good improvement effect on the dullness of facial skin and can play a whitening effect.
[0083] Comparative Example 1
[0084] Under the premise that the freeze-drying parameters of the composition are the same as those in Example 1, only the content of the multiple plant extracts in each component is changed; the specific steps are as follows:
[0085] (1) Add 3 parts of peony fresh petal squeezed stock solution, 0.5 parts of peony seed oil, 0.5 parts of tocopherol acetate, and 4 parts of glycerol into a container, stir evenly, record as solution I, and set aside;
[0086] (2) In another container, add deionized water, 3 parts of niacinamide, 2 parts of golden chamomile extract, 2 parts of honeysuckle extract, 3 parts of Panax notoginseng root extract, and 5 parts of Eucommia bark extract, stir well, and record as solution II for later use;
[0087] (3) Take 13% of the total amount of Solution II and add it to Solution I. Stir for 4 min until the solution becomes clear and transparent. Then add the remaining Solution II and stir evenly. Set aside.
[0088] (4) Add 2 parts of Glycyrrhiza glabra root extract and glycyrrhiza flavonoids complex, 0.5 parts of 3-O-ethyl ascorbic acid, 0.5 parts of PEG-20 methyl glucose sesquistearate, 0.1 parts of low molecular weight hyaluronic acid, and 1 part of inositol to the solution obtained in step (3), stir well, and record as solution III;
[0089] (5) After the solution III is placed in a freeze drying chamber, freeze drying is started to obtain the composition.
[0090] Comparative Example 2
[0091] Under the premise that the freeze-drying parameters and steps of the composition are the same as those in Example 1, only the content of the peony extract is changed, wherein 6 parts of peony fresh petal squeezed liquid and 3 parts of peony seed oil are used.
[0092] Comparative Example 3
[0093] Under the premise that the freeze-drying parameters and steps of the composition are the same as those in Example 1, only the content of the peony extract is changed, wherein 3 parts of peony fresh petal squeezed liquid and 6 parts of peony seed oil are used.
[0094] Comparative Example 4
[0095] Under the premise that the freeze-drying parameters and steps of the composition are the same as those in Example 1, only the content of the Eucommia bark extract is changed, wherein the added amount of the Eucommia bark extract is 1.6 parts.
[0096] Comparative Example 5
[0097] On the premise that the raw material components and process steps (1)-(4) are exactly the same as those in Example 1, only the conditions of the freeze-drying operation are changed, wherein the freeze-drying parameters are: the pre-freezing temperature is -15°C, and after reaching the specified pre-freezing temperature, it is continued to be maintained for 4 hours; the drying time is 8 hours, the partition temperature in the sublimation stage is 20°C, and the pressure is 15Pa.
[0098] Comparative Example 6
[0099] On the premise that the raw material components and process steps (1)-(4) are exactly the same as those in Example 1, only the freeze-drying process is changed to a high-pressure homogenization process with the process parameters of 1000 r / min and homogenization for 2 min.
[0100] Comparative Example 7
[0101] The performance of the products obtained in Comparative Examples 1-6 was evaluated, and the results are shown in Table 3.
[0102] Table 3 Product performance of comparative examples 1-6
[0103]
[0104] In addition to the results shown in the table, in fact, compared with the product obtained in Example 1, the product finally obtained in Comparative Example 1-2 is more irritating to the senses, has a strong peony fragrance, and can easily cause sneezing in people who are sensitive to floral fragrance, and the audience of the combination product is relatively narrow.
[0105] Compared with the product of Example 1, the composition product obtained in Comparative Example 3 is more greasy, has poor adsorption and adhesion to skin tissue, and has poor air permeability.
[0106] The viscosity of the composition product obtained in Comparative Example 4 is greatly improved compared with the product in Example 1, but when the product is applied to the skin, its contact with the skin is relatively tight, making it difficult to clean, and the air permeability of the product is extremely poor. Therefore, the addition amount of Eucommia bark extract must be controlled at a low level.
[0107] The product obtained in Comparative Example 5 has a loose texture and poor fineness, which may be caused by the high temperature of the freeze-drying operation and the weak mixing of the product. In addition, this study also found that when the freeze-drying temperature is too low, the freezing effect does not show a significant change and the energy consumption is high. Therefore, the freeze-drying cooling temperature is limited to -60 to -40°C.
[0108] The product obtained in Comparative Example 6 has a strong odor. Since the raw materials used in the present invention, such as 3-O-ethyl ascorbic acid, are sensitive to light and heat and contain more natural plant ingredients, the product is likely to generate high heat during the high-pressure homogenization process, causing some of the raw material components in the product to be inactivated, thereby causing the efficacy of the composition product to be impaired. Therefore, in order to avoid damage or inactivation of the raw materials in the product, the present invention does not use high-pressure homogenization to prepare the product.
Claims
1. A composition containing peony extract and having whitening effect, characterized in that: The composition comprises peony extract and a multiple plant extract composition; the peony extract is: peony fresh petal squeezed stock solution and peony seed oil; the multiple plant extract composition is: golden chamomile extract, honeysuckle flower extract, notoginseng root extract, eucommia bark extract, glycyrrhiza glabra root extract and a licorice flavonoid compound; The composition further comprises the following components: 3-O-ethyl ascorbic acid, niacinamide, PEG-20 methyl glucose sesquistearate, tocopherol acetate, low molecular weight hyaluronic acid, inositol, glycerin, and deionized water; The weight parts of each component are as follows: 0.6-6 parts of peony extract, 0.05-4.1 parts of multiple plant extract composition, 0.1-1 parts of 3-O-ethyl ascorbic acid, 0.5-5 parts of niacinamide, 0.1-1 parts of PEG-20 methyl glucose sesquistearate, 0.1-1 parts of tocopheryl acetate, 0.05-0.5 parts of low molecular weight hyaluronic acid, 0.5-3 parts of inositol, and 2-8 parts of glycerin; The peony extract comprises 0.5-5 parts of peony fresh petal squeezed liquid and 0.1-1 parts of peony seed oil; The multiple plant extract composition comprises 0.01-1 part of golden chamomile extract, 0.01-1 part of honeysuckle flower extract, 0.01-1 part of notoginseng root extract, 0.01-1 part of eucommia bark extract, 0.01-1 part of glycyrrhiza glabra root extract and 0.01-0.1 part of glycyrrhiza glabra flavonoids compound; In the compound of glycyrrhiza glabra root extract and glycyrrhiza flavonoids, glycyrrhiza glabra root extract accounts for 92% and glycyrrhiza flavonoids accounts for 8%; The composition is obtained by freeze-drying process; The freeze-drying process is specifically operated as follows: after loading the above-mentioned materials in the formula amount into the freeze-drying box, freeze-drying begins, the pre-freezing temperature is -60~-40°C, and after reaching the specified pre-freezing temperature, it is continued to be maintained for 3~5 hours; the drying time is 6~10 hours, the partition temperature in the sublimation stage is 30~50°C, and the pressure is 10~20 Pa.
2. The composition containing peony extract and having whitening effect according to claim 1, characterized in that: The weight parts of each component are as follows: 3 parts of peony fresh petal squeezed stock solution, 0.5 parts of peony seed oil, 0.05 parts of golden chamomile extract, 0.01 parts of honeysuckle extract, 0.01 parts of Panax notoginseng root extract, 0.05 parts of Eucommia bark extract, 0.02 parts of Glycyrrhiza glabra root extract and glycyrrhiza flavonoids complex, 0.5 parts of 3-O-ethyl ascorbic acid, 3 parts of niacinamide, 0.5 parts of PEG-20 methyl glucose sesquistearate, 0.5 parts of tocopheryl acetate, 0.1 parts of low molecular weight hyaluronic acid, 1 part of inositol, and 4 parts of glycerin.
3. The composition containing peony extract and having whitening effect according to claim 1, characterized in that: The composition is prepared by the following method: (1) Add the formulated amount of peony petals squeezed stock solution, peony seed oil, tocopherol acetate, and glycerin into a container and stir evenly. The mixture is referred to as solution I and is set aside. (2) Add deionized water, niacinamide, golden chamomile extract, honeysuckle flower extract, Panax notoginseng root extract, and Eucommia bark extract to another container, stir evenly, and record the solution as Solution II for later use; (3) Take 10%-15% of the total amount of Solution II and add it to Solution I. Stir for 4-5 minutes until the solution becomes clear and transparent. Then add the remaining Solution II and stir evenly. Set aside. (4) Add the root extract of Glycyrrhiza glabra and the glycyrrhiza flavonoids compound, 3-O-ethyl ascorbic acid, PEG-20 methyl glucose sesquistearate, low molecular weight hyaluronic acid, and inositol to the solution obtained in step (3), and stir evenly. This is referred to as solution III. (5) After the solution III is placed in a freeze drying chamber, freeze drying is started to obtain a composition; The freeze-drying parameters are as follows: pre-freezing temperature is -60~-40℃, and after reaching the specified pre-freezing temperature, it is maintained for 3~5 hours; drying time is 6~10 hours, the partition temperature in the sublimation stage is 30~50℃, and the pressure is 10~20 Pa.
4. The composition containing peony extract and having whitening effect according to claim 1, characterized in that: The composition can be used alone, or compounded into skin care products at an addition amount of 10%-20%.
5. The composition containing peony extract and having whitening effect according to claim 4, characterized in that: The dosage form of the skin care product can be any one of ointment, cream, lotion, liquid, essence and facial mask.
Citation Information
Patent Citations
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