A mild cosmetic composition with whitening and moisturizing effects and preparation method thereof
By adopting the synergistic effect of multiple ingredients in the cosmetic composition, the problems of single whitening ingredients and single whitening mechanism of existing cosmetic compositions are solved, and more significant whitening and moisturizing effects are achieved, providing a gentler skin care solution.
Patent Information
- Application Number
- CN202310863861.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-07-14
- Publication Date
- 2025-02-11
- Estimated Expiration
- 2043-07-14
AI Technical Summary
The whitening ingredients of existing cosmetic compositions are relatively single, and the whitening mechanism is also relatively single. They are mainly used to inhibit the production of melanin, and the synergistic effects between products are not obvious.
Using the synergistic effect of biosaccharide gum-4, oat β-glucan, plant susceptor, coenzyme Q10 and Nanopro CERA II, skin care essence is prepared, and North American witch hazel extract, mung bean fermentation broth and plant susceptor The synergistic effect of sensitizers is used to prepare a facial mask, and the synergistic effect of citrus peel extract, microalgae skin brightener, coenzyme Q10, tetraisopalmitate ascorbic acid and nonapeptide-1 are prepared to achieve the effect of whitening and moisturizing.
Through the synergy of multiple ingredients, more significant whitening and moisturizing effects are achieved, the synergy of the product is enhanced, and a gentler skin care solution is provided.
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Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of cosmetics, and in particular relates to a mild cosmetic composition with whitening and moisturizing effects and a preparation method thereof. Background Art
[0002] Since ancient times, whitening has always been an eternal topic, and healthy and rosy skin is the pursuit of modern women. However, with environmental pollution, ultraviolet damage, photoaging and aging, the skin will appear dark yellow, pigmentation and the like, so whitening products have always been one of the mainstream products in the market. In addition, the basis of healthy skin is sufficient moisture, so moisturizing is an indispensable effect of a product. Based on this, the present invention wants to produce a cosmetic composition with whitening and moisturizing effects.
[0003] CN113749971A discloses a Qidan skin care formula with anti-aging, whitening, moisturizing and skin care functions and its preparation method, using Ningxia wolfberry fruit extract and salvia miltiorrhiza flower / leaf / root extract as active components and auxiliary materials to prepare Qidan essence water, Qidan repair milk and Qidan repair cream with anti-aging, whitening and moisturizing skin care functions. The set mainly uses two Chinese herbal medicine ingredients to achieve the whitening effect, the ingredients are relatively single, and the whitening effect may not be obvious enough.
[0004] CN110279599B discloses a whitening composition, a set containing the whitening composition and a preparation method thereof. The patent uses carnosine, nonapeptide-1, yeast essence, α-arbutin, dipotassium glycyrrhizinate, dimethyl sulfone and plant natural preservatives to prepare a composition with whitening effect, and the whitening composition is made into a toner, essence and cream set. The set has rich whitening ingredients and achieves the whitening effect of the product by matching different active substances. However, the whitening mechanism of the cosmetic composition is mainly to inhibit the formation of melanin, the whitening mechanism is relatively simple, and the whitening effect may be limited.
[0005] The main disadvantages of the above technology are that the whitening ingredients are relatively simple, the whitening mechanism is also relatively simple, and it is mainly based on inhibiting the formation of melanin; in addition, the synergistic effect between the products in the cosmetic composition is not obvious. Therefore, it is necessary to develop a mild cosmetic composition with whitening and moisturizing effects to solve the problem of single whitening ingredients and single whitening mechanism in the market. Different effects are designed for different products in the set, so that the effect of each product can be maximized, and the effect of combined use can also be maximized. Summary of the invention
[0006] In view of the deficiencies of the prior art, the object of the present invention is to provide a mild cosmetic composition with whitening and moisturizing effects and a preparation method thereof.
[0007] In order to achieve the purpose of the invention, the present invention adopts the following technical solutions:
[0008] In a first aspect, the present invention provides a mild cosmetic composition with whitening and moisturizing effects, wherein the mild cosmetic composition with whitening and moisturizing effects comprises a skin care essence, a facial mask and a facial cream;
[0009] The ingredients of the skin care essence include biosaccharide gum-4, oat beta-glucan, plant allergy-relief agent, coenzyme Q10 and Nanopro CERAII;
[0010] The ingredients of the mask include witch hazel extract, mung bean fermentation liquid and plant allergy-relieving agent;
[0011] The ingredients of the cream include citrus peel extract, coenzyme Q10, ascorbyl tetraisopalmitate, microalgae skin lightening agent and nonapeptide-1.
[0012] The skin care essence of the present invention focuses on the effects of moisturizing, soothing and repairing the skin, and the above effects are achieved through the synergistic effect of biosaccharide gum-4, oat β-glucan, Nanopro CERA II, plant allergy-relieving agents and coenzyme Q10. The facial mask focuses on the effects of anti-oxidation and soothing, and the above effects are achieved through the synergistic effect of North American witch hazel extract, mung bean fermentation liquid and plant allergy-relieving agents. The facial cream focuses on the effects of whitening and antioxidant, and the above effects are achieved through the synergistic effect of citrus peel extract, microalgae skin lightening agent, coenzyme Q10, ascorbyl tetraisopalmitate and nonapeptide-1.
[0013] Biosaccharide Gum-4 can form a moisturizing film on the skin, which can keep the skin moisturized for a long time, resist pollution and prevent skin sensitivity. It can protect the skin from air pollution, UV damage and pollution from daily necessities. Due to its shielding effect, Biosaccharide Gum-4 can prevent PM2.5-induced intracellular oxidative stress and protect the epidermis; prevent mitochondria from PM2.5-induced toxicity and protect key cell metabolism; protect fat from pollution-induced oxidation and protect the structure and function of the skin.
[0014] Oat β-glucan is a polysaccharide with deep moisturizing effect. It can maintain the moisture in the dermis connective tissue, keep it in a loose state, automatically adjust the water retention according to environmental changes, and keep the skin in the best physiological state.
[0015] Plant allergy relievers have a broad-spectrum antibacterial effect. The inhibition rate of 200ppm of plant allergy relievers on the release of histamine can reach 54.7%, which can effectively alleviate skin allergic symptoms.
[0016] Coenzyme Q10 has antioxidant and energy-generating effects, prevents aging, and delays the occurrence of wrinkles and skin sagging; it can effectively replenish cell energy, promote skin collagen synthesis, delay skin aging, reduce wrinkles, and restore skin luster and elasticity; it can repair damage to cells caused by free radicals and protect fragile skin; it can stimulate the formation of epidermal fibroblasts and hyaluronic acid, and has a moisturizing and hydrating effect; it can promote cell metabolism, remove blood waste, effectively inhibit melanin, and improve dull skin.
[0017] Nanopro CERA II is an encapsulated ceramide that can provide deep and long-lasting moisturizing, has extremely strong skin repair function, can improve skin elasticity and delay aging; it has excellent soothing function and can effectively prevent skin allergies; at the same time, it uses unique nano-soft body technology, which has the advantages of small particle size, stable structure and good penetration performance.
[0018] Witch hazel contains a plant compound called catechins. Catechins are a type of flavonoid known for reducing oxidative stress, which can minimize the damage to skin cells. At the same time, witch hazel contains a high concentration of tannic acid, which is a polyphenol that can precipitate proteins that overflow from the skin, inhibit the secretion of sebum and sweat glands, shrink local capillaries, reduce permeability, and neutralize local acidic and alkaline substances. Therefore, it has good astringent and anti-inflammatory effects.
[0019] Mung bean fermented liquid is an active ingredient obtained from mung bean seeds using cold fermentation technology. It is rich in tannins, sterols and flavonoids, etc. It has the effects of repairing, soothing and protecting the skin, can inhibit the activity of tumor necrosis factor, IL2, IL2, and cyclooxygenase 2, and has the functions of promoting collagen synthesis, repairing dermal papillae and strengthening the epidermal barrier.
[0020] Citrus peel extract is a natural orange peel extract essence, which contains unique hesperidin, which directly acts on the outer stratum corneum of the skin, improves the structure of keratinized cells, makes the epidermal keratinized cells flat and tense, and reduces the intercellular gap. After the stratum corneum is arranged in a healthy and neat manner, it refracts light evenly and naturally, making the skin translucent, shiny, delicate and radiant. It is not the whitening, hydrating and moisturizing that are often talked about in the past, but a healthy and safe skin care raw material for repairing keratin for bright and clear skin. It achieves a healthy and whitening effect of transparent and bright skin by repairing the keratin barrier.
[0021] Ascorbyl tetraisopalmitate is a derivative of VC, which solves the disadvantage of unstable vitamin C while maintaining the activity of vitamin C. Vitamin C has a wide range of functions. As one of the antioxidants with the highest content in the epidermis and dermis, it can also promote collagen regeneration, anti-inflammatory, treat acne, inhibit melanin production, etc., and the modified ascorbyl tetraisopalmitate also has the same effect.
[0022] Microalgae skin lightener has the effect of maintaining natural skin color, reducing age spots, and balancing skin color. It does not change the tyrosinase activity in melanocytes and can maintain natural skin color. When melanin production is stimulated, it has an intelligent melanin regulating effect, thereby balancing skin color and eliminating spots. Under the condition of melanogenesis, it selectively reduces melanogenesis by regulating the synthesis of nitric oxide, and reduces the transfer of melanin by reducing the activity of p70S6 kinase. Microalgae skin lightener can only reduce inflammation and melanocyte proliferation under the condition of melanogenesis (which occurs in age spots for a long time).
[0023] Nonapeptide-1 reduces melanin production by inhibiting MC-1 and preventing excessive melanin production.
[0024] Preferably, the mild cosmetic composition with whitening and moisturizing effects further comprises skin care water and / or massage honey.
[0025] The ingredients of the skin care water include moisturizer, carnosine and kava extract.
[0026] Carnosine is a dipeptide composed of two amino acids, β-alanine and L-histidine. It has a strong antioxidant capacity and can remove reactive oxygen free radicals (ROS) and α-β unsaturated aldehydes formed by excessive oxidation of fatty acids in cell membranes during oxidative stress.
[0027] Kava extract has an immediate calming and soothing effect, acting on nerve endings, blocking neuronal transmission by occupying GABAA receptors through capsaicin and inhibiting PGE2 (prostaglandin PEG2 is a known mediator of inflammation that can cause pain), thereby inhibiting the transmission of sensitivity.
[0028] The massage honey comprises ingredients of resveratrol fermentation product, lemon peel extract, kava extract, plant allergy reliever and coenzyme Q10.
[0029] The skin care water of the present invention focuses on the moisturizing and anti-oxidation effects, while the massage honey mainly focuses on the whitening and anti-oxidation effects.
[0030] Resveratrol is a natural antioxidant found in plants. Its antioxidant mechanism is mainly to remove or inhibit the generation of free radicals, inhibit lipid peroxidation, and regulate the activity of antioxidant-related enzymes. It can inhibit cell proliferation, significantly inhibit the activity of intracellular tyrosinase, and significantly reduce the content of intracellular melanin, thereby playing a role in whitening and removing spots. Resveratrol can also effectively resist aging caused by lipid peroxides caused by free radicals and their metabolites, solving the problem of skin damage from the root, resisting skin aging, and achieving the effect of reverse growth.
[0031] Tyrosinase is a key enzyme in the synthesis of melanin in organisms. It is directly involved in the oxidation process of melanin synthesis and is closely related to human aging. The increased expression and activity of tyrosinase can increase the synthesis of pigments in melanocytes, causing the skin to darken. The activity of tyrosinase determines the amount of melanin synthesis. Inhibiting its activity can reduce the synthesis of melanin. Lemon peel contains substances that inhibit the activity of tyrosinase, thereby inhibiting the formation of melanin and achieving a whitening effect. At the same time, lemons are rich in vitamin C and antioxidant ingredients. Using lemons for beauty and skin care can achieve good effects such as freckle removal, whitening, and anti-aging. It can prevent and eliminate the deposition of skin pigments, and can deeply cleanse the skin and increase facial elasticity.
[0032] Preferably, the skin care essence comprises, by mass percentage, 2-5% of biosaccharide gum-4, 1-3% of oat beta-glucan, 0.1-2% of plant allergen, 0.1-0.5% of coenzyme Q10, 0.5-2% of Nanopro CERA II and water.
[0033] When Biosaccharide Gum-4, oat beta-glucan, plant allergy-relief agent, Nanopro CERA II and coenzyme Q10 are added in the above-mentioned specific mass percentages, the skin care essence has the best effect in hydrating, soothing and repairing the skin.
[0034] The mass percentage of the biosaccharide gum-4 can be selected from 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, 5%, etc., the mass percentage of the oat β-glucan can be selected from 1%, 1.5%, 2%, 2.5%, 3%, etc., the mass percentage of the plant allergy-relieving agent can be selected from 0.1%, 0.3%, 0.5%, 0.7%, 1%, 1.2%, 1.4%, 1.6%, 1.8%, 2%, etc., the mass percentage of the coenzyme Q10 can be selected from 0.1%, 0.15%, 0.2%, 0.25%, 0.3%, 0.35%, 0.4%, 0.45%, 0.5%, etc., the Nanopro CERA The mass percentage of II can be selected as 0.5%, 0.7%, 0.9%, 1.1%, 1.3%, 1.5%, 1.7%, 2%, etc. Other specific point values within the above numerical range can also be selected, and they will not be described one by one here.
[0035] Preferably, the plant allergy-relieving agent includes Centella asiatica extract, Polygonum cuspidatum root extract, Scutellaria baicalensis root extract, tea extract, licorice extract, chamomile flower extract and rosemary extract.
[0036] Preferably, the Nanopro CERA II comprises ceramide NS / ceramide NG, lecithin, tocopheryl acetate, octyldodecanol and glycerin.
[0037] Preferably, the skin care essence further comprises any one of a thickener, a moisturizer, an antibacterial agent or an antioxidant component, or a combination of at least two thereof.
[0038] Preferably, the skin care essence further comprises, by mass percentage, any one of 0.3-0.5% thickener, 3.5-10% moisturizer, 1-2% antibacterial agent or 1-5% antioxidant ingredient, or a combination of at least two thereof.
[0039] The mass percentage of the thickener can be selected from 0.3%, 0.35%, 0.4%, 0.45%, 0.5%, etc., the mass percentage of the moisturizer can be selected from 3.5%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, etc., the mass percentage of the antibacterial agent can be selected from 1%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, 1.6%, 1.7%, 1.8%, 1.9%, 2%, etc., the mass percentage of the antioxidant component can be selected from 1%, 1.5%, 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, 5, etc., and other specific point values within the above numerical range can be selected, which will not be repeated here.
[0040] Preferably, the facial mask comprises, by mass percentage, 2-5% of witch hazel extract, 0.3-1% of mung bean fermentation liquid, 0.3-1.5% of plant allergy-relieving agent and water.
[0041] When witch hazel extract, mung bean fermentation liquid and plant allergy-relieving agent are added in the above-mentioned specific mass percentage, the antioxidant and allergy-relieving effect of the mask is optimal.
[0042] The mass percentage of the North American witch hazel extract can be selected from 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, 5%, etc., the mass percentage of the mung bean fermentation liquid can be selected from 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, etc., the mass percentage of the plant allergy-relieving agent can be selected from 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, etc., and other specific point values within the above numerical range can be selected, which will not be repeated here one by one.
[0043] Preferably, the facial mask further comprises any one of a thickener, a moisturizer, a chelating agent, an active ingredient, a pH neutralizer or an antibacterial agent, or a combination of at least two thereof.
[0044] Preferably, the active ingredient comprises diethoxyethyl succinate and / or water-soluble ceramide.
[0045] Water-soluble ceramide is a mixture of sphingomyelin (ceramide) and phospholipids extracted from rice bran shells. It is a homologue of natural ceramide in the human body. Ceramide is the most important component of the interstitial matrix of stratum corneum cells, representing 40% of lipids, and is the key to the formation of the skin's protective barrier. Water-soluble ceramide can help replenish the ceramide that the skin lacks, reconstruct the skin barrier, increase the skin's water retention capacity, and make the skin soft, smooth, and restore elasticity.
[0046] Preferably, the facial mask further comprises any one of 0.1-0.3% thickener, 2-5% moisturizer, 0.01-0.06% chelating agent, 0.5-2% active ingredient, 0.005-0.03% pH neutralizer or 1-2% antibacterial agent, or a combination of at least two thereof.
[0047] The mass percentage of the thickener can be selected from 0.1%, 0.15%, 0.2%, 0.25%, 0.3%, etc., the mass percentage of the moisturizer can be selected from 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, 5%, etc., the mass percentage of the chelating agent can be selected from 0.01%, 0.02%, 0.03%, 0.04%, 0.05%, 0.06%, etc., the mass percentage of the active ingredient can be selected from 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, 1.1%, 1.2%, etc. The mass percentage of the pH neutralizer can be selected from 0.005%, 0.01%, 0.015%, 0.02%, 0.025%, 0.03% and the like; the mass percentage of the antibacterial agent can be selected from 1%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, 1.6%, 1.7%, 1.8%, 1.9%, 2% and the like; other specific point values within the above numerical range can be selected, which will not be described one by one here.
[0048] Preferably, the facial cream comprises 0.5-2% of citrus peel extract, 0.1-0.5% of coenzyme Q10, 0.3-2% of ascorbyl tetraisopalmitate, 0.3-1.5% of microalgae skin lightening agent, 1-100 ppm of nonapeptide-1 and water.
[0049] When citrus peel extract, coenzyme Q10, ascorbyl tetraisopalmitate, microalgae skin lightening agent, and nonapeptide-1 are added in the above-mentioned specific mass percentages, the whitening and antioxidant effects of the cream are optimal.
[0050] The mass percentage of the citrus peel extract can be selected from 0.5%, 0.7%, 1%, 1.2%, 1.5%, 1.8%, 2%, etc., the mass percentage of the coenzyme Q10 can be selected from 0.1%, 0.15%, 0.2%, 0.25%, 0.3%, 0.35%, 0.4%, 0.45%, 0.5%, etc., the mass percentage of ascorbyl tetraisopalmitate can be selected from 0.3%, 0.5%, 0.8%, 1%, 1.2%, 1.4%, 1.6%, 1.8%, 2%, etc., the microalgae The mass percentage of the skin lightening agent can be selected from 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, etc., and the mass percentage of the nonapeptide-1 can be selected from 1ppm, 10ppm, 20ppm, 30ppm, 40ppm, 50ppm, 60ppm, 70ppm, 80ppm, 90ppm, 100ppm, etc. Other specific point values within the above numerical range can be selected, so they will not be described one by one here.
[0051] The addition of 10 ppm of nonapeptide-1 can be converted to 0.1%.
[0052] Preferably, the microalgae skin lightening agent comprises 1,3-propylene glycol, lutein, lecithin, sodium ascorbate and tocopherol.
[0053] Preferably, the facial cream further comprises any one or a combination of at least two of a thickener, an emulsifier, a fat, a moisturizer, a soothing ingredient, a pH neutralizer or an antibacterial agent.
[0054] Preferably, the facial cream further comprises, by mass percentage, any one of 0.35-0.6% thickener, 3-6% emulsifier, 6-10% oil, 7-15% moisturizer, 0.8-4.5% soothing ingredient, 0.07-0.16% pH neutralizer or 1-2% antibacterial agent, or a combination of at least two thereof.
[0055] The mass percentage of the thickener can be selected from 0.35%, 0.4%, 0.45%, 0.5%, 0.55%, 0.6%, etc., the mass percentage of the emulsifier can be selected from 3%, 3.5%, 4%, 4.5%, 5%, 5.5%, 6%, etc., the mass percentage of the oil can be selected from 6%, 6.5%, 7%, 7.5%, 8%, 8.5%, 9%, 9.5%, 10%, etc., the mass percentage of the moisturizer can be selected from 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, etc., and the mass percentage of the soothing component can be selected from 0.8%, 1%, 1.2%, 1.5%. , 1.8%, 2%, 2.2%, 2.5%, 2.8%, 3%, 3.2%, 3.5%, 3.8%, 4%, 4.2%, 4.5%, etc., the mass percentage of the pH neutralizer can be selected from 0.07%, 0.08%, 0.09%, 0.1%, 0.11%, 0.12%, 0.13%, 0.14%, 0.15%, 0.16%, etc., the mass percentage of the antibacterial agent can be selected from 1%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, 1.6%, 1.7%, 1.8%, 1.9%, 2%, etc., other specific point values within the above numerical range can be selected, so they will not be repeated here one by one.
[0056] Preferably, the skin care water comprises, by mass percentage, 1-8% of moisturizer, 0.02-0.2% of carnosine, 0.5-2% of kava extract and water.
[0057] When the moisturizer, carnosine and kava extract are added in the above specific mass percentage, the moisturizing and anti-oxidation effects of the skin care water are optimal.
[0058] The mass percentage of the moisturizing agent can be selected from 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8% and the like; the mass percentage of the carnosine can be selected from 0.02%, 0.04%, 0.06%, 0.08%, 0.1%, 0.12%, 0.14%, 0.16%, 0.18%, 0.2% and the like; the mass percentage of the kava extract can be selected from 0.5%, 0.8%, 1%, 1.2%, 1.5%, 1.8%, 2% and the like; other specific point values within the above numerical range can be selected, which will not be described one by one here.
[0059] Preferably, the moisturizing agent comprises any one of oat β-glucan, hydroxyethyl urea, biosaccharide gum-1, tremella polysaccharide or AQUA-MIX or a combination of at least two thereof, and the AQUA-MIX comprises urea, yeast amino acids, trehalose, inositol, taurine and betaine.
[0060] AQUA-MIX can upregulate the gene expression of the water channel protein AQP-3 and regulate the water balance inside and outside the cells through small molecule permeabilizers; oat β-glucan is a polysaccharide with deep moisturizing effect. It can maintain the moisture in the dermal connective tissue and keep it in a loose state. It automatically adjusts the water retention according to environmental changes to keep the skin in the best physiological state; hydroxyethyl urea can soften the stratum corneum and increase the transdermal absorption of active nutrients; biosaccharide gum-1 can form a smooth moisturizing film on the skin surface to prevent the loss of skin moisture.
[0061] Preferably, the skin care water further comprises any one of a thickener, a pH regulator, adenosine or an antibacterial agent, or a combination of at least two thereof.
[0062] Preferably, the skin care lotion further comprises, by mass percentage, any one of 0.02-0.1% thickener, 0.005-0.05% pH adjuster, 0.02-0.1% adenosine or 1-3% antibacterial agent, or a combination of at least two thereof.
[0063] The mass percentage of the thickener can be selected from 0.02%, 0.03%, 0.04%, 0.05%, 0.06%, 0.07%, 0.08%, 0.09%, 0.1%, etc., the mass percentage of the pH adjuster can be selected from 0.005%, 0.01%, 0.02%, 0.03%, 0.04%, 0.05%, etc., the mass percentage of adenosine can be selected from 0.02%, 0.03%, 0.04%, 0.05%, 0.06%, 0.07%, 0.08%, 0.09%, 0.1%, etc., the mass percentage of the antibacterial agent can be selected from 1%, 1.5%, 2%, 2.5%, 3%, etc., and other specific point values within the above numerical range can be selected, which will not be repeated here.
[0064] Preferably, the massage honey comprises, by mass percentage, 0.1-1% of resveratrol fermentation product, 0.1-1% of lemon peel extract, 0.1-0.6% of coenzyme Q10, 0.3-1% of kava extract, 0.5-2% of plant allergy reliever and water.
[0065] When resveratrol fermentation product, lemon peel extract, coenzyme Q10, kava extract and plant allergy-relieving agent are added in the above-mentioned specific mass percentage, the whitening and antioxidant effect of massage honey is optimal.
[0066] The mass percentage of the resveratrol fermentation product can be selected from 0.1%, 0.2%, 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, etc., the mass percentage of the lemon peel extract can be selected from 0.1%, 0.2%, 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, etc., the mass percentage of the coenzyme Q10 can be selected from 0.1%, The mass percentage of the kava extract can be selected from 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, etc., the mass percentage of the plant allergy-relieving agent can be selected from 0.5%, 0.8%, 1%, 1.2%, 1.5%, 1.8%, 2%, etc., and other specific point values within the above numerical range can be selected, which will not be repeated here.
[0067] Preferably, the massage honey further comprises any one of a thickener, a moisturizer, a grease, an antibacterial agent or a pH neutralizer, or a combination of at least two thereof.
[0068] Preferably, the massage honey further comprises, by mass percentage, any one of 0.5-1.5% thickener, 15-37% moisturizer, 0.3-1.2% oil, 0.7-2% antibacterial agent or 0.02-0.12% pH neutralizer or a combination of at least two thereof.
[0069] The mass percentage of the thickener can be selected from 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, etc., the mass percentage of the moisturizer can be selected from 15%, 18%, 20%, 23%, 25%, 28%, 30%, 33%, 35%, 37%, etc., the mass percentage of the oil can be selected from 0.3%, 0.5%, 0.7%, 0.9%, 1%, 1.2%, 1.3%, 1.4%, 1.5%, etc. %, etc., the mass percentage of the antibacterial agent can be selected from 0.7%, 0.8%, 0.9%, 1%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, 1.6%, 1.7%, 1.8%, 1.9%, 2%, etc., the mass percentage of the pH neutralizer can be selected from 0.02%, 0.04%, 0.06%, 0.08%, 0.1%, 0.12%, etc., and other specific point values within the above numerical range can be selected, which will not be repeated here one by one.
[0070] In a second aspect, the present invention provides a method for preparing a mild cosmetic composition with whitening and moisturizing effects according to the first aspect, the preparation method comprising: physically mixing the respective raw materials for preparing a skin care essence, a facial mask, a facial cream, an optional skin care water, and an optional massage honey.
[0071] Preferably, in the preparation method of the skin care water, the mixing temperature of water, moisturizer, carnosine and kava extract is below 40°C, for example 20°C, 25°C, 30°C, 35°C, 40°C, etc. Other specific point values within the above numerical range can be selected and will not be described here one by one.
[0072] Preferably, in the preparation method of the skin care essence, the mixing temperature of water, biosaccharide gum-4, oat β-glucan, plant allergen, coenzyme Q10, and Nanopro CERA II is below 40°C, for example, 20°C, 25°C, 30°C, 35°C, 40°C, etc. Other specific point values within the above numerical range can be selected, and they will not be described one by one here.
[0073] Preferably, in the preparation method of the massage honey, the mixing temperature of water, resveratrol fermentation product, lemon peel extract, kava extract, plant allergy-relieving agent and coenzyme Q10 is below 40°C, for example, 20°C, 25°C, 30°C, 35°C, 40°C, etc. Other specific point values within the above numerical range can be selected, and they will not be described one by one here.
[0074] Preferably, in the preparation method of the facial mask, the mixing temperature of water, witch hazel extract, mung bean fermentation liquid and plant allergy-relieving agent is below 40°C, for example, 20°C, 25°C, 30°C, 35°C, 40°C, etc. Other specific point values within the above numerical range can be selected, and they will not be described one by one here.
[0075] Preferably, in the preparation method of the facial cream, the mixing temperature of water, citrus peel extract, coenzyme Q10, ascorbyl tetraisopalmitate, microalgae skin lightening agent, and nonapeptide-1 is below 40°C, for example, 20°C, 25°C, 30°C, 35°C, 40°C, etc. Other specific point values within the above numerical range can be selected, and they will not be described one by one here.
[0076] Compared with the prior art, the present invention has the following beneficial effects:
[0077] The skin care essence of the present invention focuses on the effects of moisturizing, soothing and repairing the skin, and the above effects are achieved through the synergistic effect of biosaccharide gum-4, oat β-glucan, Nanopro CERA II, plant allergy-relieving agents and coenzyme Q10. The facial mask focuses on the effects of anti-oxidation and soothing, and the above effects are achieved through the synergistic effect of North American witch hazel extract, mung bean fermentation liquid and plant allergy-relieving agents. The facial cream focuses on the effects of whitening and antioxidant, and the above effects are achieved through the synergistic effect of citrus peel extract, microalgae skin lightening agent, coenzyme Q10, ascorbyl tetraisopalmitate and nonapeptide-1. DETAILED DESCRIPTION
[0078] In order to further explain the technical means and effects adopted by the present invention, the technical solution of the present invention is further described below in conjunction with the preferred embodiments of the present invention, but the present invention is not limited to the scope of the embodiments.
[0079] The sources of the functional ingredients contained in the products involved in the following embodiments and comparative examples are as follows (only the functional ingredients are reflected, and the necessary auxiliary ingredients contained in other commercially available raw materials are not repeated):
[0080] Biosaccharide Gum-4 is a product purchased from Yujin Company under the trade name of saccharide film protective agent;
[0081] Oat β-glucan was purchased from Yiwan Company under the trade name FangYe5021 oat β-glucan;
[0082] The plant allergy reliever was purchased from Guangzhou Peitao Company under the trade name ON-MEDI LINE;
[0083] Coenzyme Q10 was purchased from Suzhou Nakang Company under the trade name of Q10;
[0084] Ammonium acryloyldimethyltaurate / VP copolymer is a product purchased from Aristoflex Company under the trade name Aristoflex AVC;
[0085] AQUA-MIX is a product purchased from Zhaohan Company. Products of AQP3;
[0086] Nanopro CERA II is a product purchased from Ruxi Company under the trade name Nanopro CERA II;
[0087] Nonapeptide-1 was purchased from Guangzhou Peitao Company under the trade name of fe-peptide;
[0088] The North American witch hazel extract was purchased from Zhaohan Company under the trade name WHL's products;
[0089] Mung bean fermented liquid was purchased from Keqihua Company under the trade name of COLLAMUNG WATER SOLUBLE mung bean fermented liquid;
[0090] The citrus peel extract was purchased from Jiufeng Company under the trade name MandarinClear;
[0091] Carnosine was purchased from Guangzhou Peitao Company under the trade name of S-Carnosine LCS;
[0092] Water-soluble ceramide was purchased from Zhaohan Company under the trade name PGLY's products;
[0093] HAMIN-C is a product purchased from Peitao Company under the trade name HAMIN-C;
[0094] Argania spinosa kernel oil was purchased from Runpei Corporation under the trade name ARGAN OIL;
[0095] Shea butter was purchased from Hailan Company under the trade name Products of SB 45;
[0096] Biosaccharide Gum-1 was purchased from Yujin Company under the trade name 1.5P products;
[0097] Ascorbyl tetraisopalmitate was purchased from Bovitt Company under the trade name VC-IP;
[0098] The microalgae skin lightening agent was purchased from Bochi Company under the trade name LightSKN CN's products;
[0099] Kava extract was purchased from Yujin Company under the trade name of Beline products;
[0100] Hydroxyethyl urea was purchased from Bio-Bio Corporation under the trade name products;
[0101] Tremella polysaccharide was purchased from Haotai Company under the trade name Tremella fuciformis polysaccharide (WSK);
[0102] AT 100P is a product purchased from Hailan Company with the trade name of AT 100P;
[0103] The resveratrol fermented product was purchased from Zhaohan Company under the trade name of ARBOR PICHI resveratrol fermented product;
[0104] Lemon peel extract was purchased from Zhaohan Company under the trade name LPW's products;
[0105] HL-01 is a product purchased from Hailan Company under the trade name Naturecare HL-01;
[0106] Sodium polyacrylate was purchased from Shaanxi Yuanyou Biotechnology Co., Ltd. under the trade name of sodium polyacrylate;
[0107] BioStine HP is a product purchased from BIONEST, Taiwan, China, with the trade name HP Skin Tightening Agent / BioStine HP;
[0108] Zeastat TM Zeasat was purchased from Shanghai Haoyun Trading Co., Ltd. TM products;
[0109] Carbomer is a product purchased from Zhaoheng Company with the trade name of Carbomer 940 thickener;
[0110] Xanthan gum was purchased from Noran Corporation under the trade name Cosphaderm X34;
[0111] PC 2000 is a product purchased from ANGUS Neutralizer Company of the United States under the trade name AMP-ULTRA PC2000;
[0112] HL-02 PLUS is a product purchased from Hailan Company with the trade name of HL-02 PLUS.
[0113] Preparation Example 1
[0114] The present preparation example provides a skin care essence, the composition of which is: 0.35% of ammonium acryloyldimethyltaurate / VP copolymer, 0.01% of sodium polyacrylate, 2.7% of butylene glycol, 1% of glycerol, 0.5% of trehalose, 0.1% of Tremella polysaccharide, 0.01% of AQUA-MIX, 2% of oat β-glucan, 3% of biosaccharide gum-4, 1.2% of Nanopro CERA II, 0.5% of plant allergen, 0.3% of coenzyme Q10, 0.8% of BioStine HP, 0.01% of nonapeptide-1, 0.3% of p-hydroxyacetophenone, 0.3% of 1,2-hexanediol, and 0.5% of Zeastat. TM0.6% and water balance;
[0115] The preparation method is as follows: water, ammonium acryloyldimethyltaurate / VP copolymer, trehalose, and Tremella polysaccharide are mixed at 78°C, kept warm for 8 minutes, cooled to 48°C, and mixed with p-hydroxyacetophenone, 1,2-hexanediol, and Zeastat TM , butylene glycol, cool to 35°C and mix with biosaccharide gum-4, oat β-glucan, plant allergen, coenzyme Q10, AQUA-MIX, Nanopro CERAII, nonapeptide-1, BioStine HP, glycerin and sodium polyacrylate to obtain.
[0116] Preparation Example 2
[0117] The present preparation example provides a skin care essence, the composition of which is: 0.25% ammonium acryloyldimethyltaurate / VP copolymer, 0.03% sodium polyacrylate, 4% butylene glycol, 2% glycerol, 1% trehalose, 0.05% tremella polysaccharide, 0.05% AQUA-MIX, 1% oat β-glucan, 4% biosaccharide gum-4, 0.5% Nanopro CERA II, 1% plant allergen, 0.15% coenzyme Q10, 1% BioStine HP, 0.03% nonapeptide-1, 0.4% p-hydroxyacetophenone, 0.2% 1,2-hexanediol, and 0.5% Zeastat. TM 0.7% and water balance;
[0118] The preparation method is as follows: water, ammonium acryloyldimethyltaurate / VP copolymer, trehalose, and Tremella polysaccharide are mixed at 80°C, kept warm for 5 minutes, cooled to 50°C, and mixed with p-hydroxyacetophenone, 1,2-hexanediol, and Zeastat TM , butylene glycol, cool to 30°C and mix with biosaccharide gum-4, oat β-glucan, plant allergen, coenzyme Q10, AQUA-MIX, Nanopro CERAII, nonapeptide-1, BioStine HP, glycerin and sodium polyacrylate to obtain.
[0119] Preparation Example 3
[0120] The present preparation example provides a skin care essence, the composition of which is: 0.4% ammonium acryloyldimethyltaurate / VP copolymer, 0.02% sodium polyacrylate, 2% butylene glycol, 3% glycerol, 1.5% trehalose, 0.15% tremella polysaccharide, 0.1% AQUA-MIX, 3% oat β-glucan, 2% biosaccharide gum-4, 2% Nanopro CERA II, 1.5% plant allergen, 0.4% coenzyme Q10, 1.5% BioStine HP, 0.1% nonapeptide-1, 0.5% p-hydroxyacetophenone, 0.3% 1,2-hexanediol, and 0.5% Zeastat. TM 0.5% and water balance;
[0121] The preparation method is as follows: water, ammonium acryloyldimethyltaurate / VP copolymer, trehalose, and Tremella polysaccharide are mixed at 75°C, kept warm for 10 minutes, cooled to 45°C, and mixed with p-hydroxyacetophenone, 1,2-hexanediol, and Zeastat TM , butylene glycol, cool to 40°C and mix with biosaccharide gum-4, oat β-glucan, plant allergen, coenzyme Q10, AQUA-MIX, Nanopro CERAII, nonapeptide-1, BioStine HP, glycerin and sodium polyacrylate to obtain.
[0122] Preparation Example 4
[0123] The present preparation example provides a facial mask, the composition of which is: 0.12% carbomer, 0.03% xanthan gum, 0.15% ammonium acryloyldimethyltaurate / VP copolymer, 0.03% EDTA-2Na, 0.3% betaine, 1% butylene glycol, 2% methylpropanediol, 4% witch hazel extract, 0.7% mung bean fermentation liquid, 0.5% plant allergen, 0.25% carnosine, 0.3% diethoxyethyl succinate, 1% water-soluble ceramide, 0.01% PC 2000, 0.5% 1,2-pentanediol, 0.25% 1,2-hexanediol, and 0.5% Zeastat. TM 0.6% and water balance;
[0124] The preparation method is as follows: water, carbomer, xanthan gum, ammonium acryloyldimethyltaurate / VP copolymer, betaine, butylene glycol, methylpropanediol, and EDTA-2Na are mixed at 78°C, kept warm for 8 minutes, cooled to 63°C and mixed with PC 2000, cooled to 48°C and mixed with 1,2-pentanediol, 1,3-propylene glycol, and Zeastat TM Mix, cool to 35°C, and mix with North American witch hazel extract, mung bean fermentation liquid, plant allergy-relieving agent, carnosine, water-soluble ceramide, and diethoxyethyl succinate to obtain.
[0125] Preparation Example 5
[0126] The present preparation example provides a facial mask, the composition of which is: 0.05% carbomer, 0.05% xanthan gum, 0.2% ammonium acryloyldimethyltaurate / VP copolymer, 0.02% EDTA-2Na, 1% betaine, 2% butylene glycol, 1% methylpropanediol, 2% witch hazel extract, 0.5% mung bean fermentation liquid, 1.5% plant allergen, 0.1% carnosine, 0.5% diethoxyethyl succinate, 1.5% water-soluble ceramide, 0.03% PC 2000, 0.8% 1,2-pentanediol, 0.4% 1,2-hexanediol, and zeastat. TM 0.5% and water balance;
[0127] The preparation method is as follows: water, carbomer, xanthan gum, ammonium acryloyldimethyltaurate / VP copolymer, betaine, butylene glycol, methylpropanediol, and EDTA-2Na are mixed at 80°C, kept warm for 5 minutes, cooled to 65°C and mixed with PC 2000, cooled to 50°C and mixed with 1,2-pentanediol, 1,3-propylene glycol, and Zeastat TM The mixture is mixed, cooled to 40°C, and mixed with witch hazel extract, mung bean fermentation liquid, plant allergy-relieving agent, carnosine, water-soluble ceramide, and diethoxyethyl succinate to obtain the product.
[0128] Preparation Example 6
[0129] The present preparation example provides a facial mask, the composition of which is: 0.15% carbomer, 0.02% xanthan gum, 0.1% ammonium acryloyldimethyltaurate / VP copolymer, 0.04% EDTA-2Na, 0.1% betaine, 0.5% butylene glycol, 3% methylpropanediol, 5% witch hazel extract, 0.3% mung bean fermentation liquid, 0.3% plant allergen, 0.4% carnosine, 0.15% diethoxyethyl succinate, 0.5% water-soluble ceramide, 0.005% PC 2000, 0.3% 1,2-pentanediol, 0.2% 1,2-hexanediol, and Zeastat. TM 0.7% and water balance;
[0130] The preparation method is as follows: water, carbomer, xanthan gum, ammonium acryloyldimethyltaurate / VP copolymer, betaine, butylene glycol, methylpropanediol, and EDTA-2Na are mixed at 75°C, kept warm for 10 minutes, cooled to 60°C and mixed with PC 2000, cooled to 45°C and mixed with 1,2-pentanediol, 1,3-propylene glycol, and Zeastat TM Mix, cool to 30°C, and mix with witch hazel extract, mung bean fermentation liquid, plant allergy-relieving agent, carnosine, water-soluble ceramide, and diethoxyethyl succinate to obtain.
[0131] Preparation Example 7
[0132] The preparation example provides a facial cream, the composition of which is: carbomer 0.26%, ammonium acryloyldimethyltaurate / VP copolymer 0.2%, HAMIN-C 4%, argania spinosa kernel oil 1%, triethylhexanoin 3%, shea butter 0.7%, tocopherol acetate 0.8%, hexyldecyl myristoyl methylaminopropionate 2%, butylene glycol 2.7%, glycerol 2%, tremella polysaccharide 0.07%, allantoin 0.1%, oat beta glucan 3%, biosaccharide gum-1 2%, citrus peel extract 1%, ascorbyl tetraisopalmitate 2%, coenzyme Q10 0.3%, microalgae skin lightening agent 1%, nonapeptide-1 0.3%, kava extract 0.5%, plant allergy-relieving agent 2%, bisabolol 0.2%, PC 2000 0.1%, p-hydroxyacetophenone 0.3%, 1,2-hexanediol 0.3%, Zeastat TM 0.6% and water balance;
[0133] The preparation method comprises the following steps: mixing p-hydroxyacetophenone and butylene glycol at 72° C. to obtain a first preform; mixing water, carbomer, ammonium acryloyldimethyltaurate / VP copolymer, glycerol, tremella polysaccharide, and allantoin at 78° C.; cooling to 72° C. and mixing with HAMIN-C, argania spinosa kernel oil, triethylhexanoin, shea butter, tocopherol acetate, hexyldecyl myristoyl methylaminopropionate, and bisabolol; cooling to 63° C. and mixing with PC 2000; cooling to 48° C. and mixing with 1,2-hexanediol, the first preform, and Zeastatin. TM Mix, cool to 35°C, and mix with biosaccharide gum-1, oat beta-glucan, citrus peel extract, ascorbyl tetraisopalmitate, coenzyme Q10, microalgae skin brightening agent, nonapeptide-1, kava extract, and plant allergy-relieving agent to obtain.
[0134] Preparation Example 8
[0135] The preparation example provides a facial cream, the composition of which is: carbomer 0.32%, ammonium acryloyldimethyltaurate / VP copolymer 0.1%, HAMIN-C 5%, argania spinosa kernel oil 2%, triethylhexanoin 4%, shea butter 1%, tocopherol acetate 0.5%, hexyldecyl myristoyl methylaminopropionate 1%, butylene glycol 4%, glycerol 1%, tremella polysaccharide 0.03%, allantoin 0.2%, oat beta glucan 5%, biosaccharide gum-1 1%, citrus peel extract 2%, ascorbyl tetraisopalmitate 0.5%, coenzyme Q10 0.5%, microalgae skin lightening agent 1.5%, nonapeptide-1 0.8%, kava extract 1%, plant allergy-relieving agent 1.5%, bisabolol 0.3%, PC 2000 0.13%, p-hydroxyacetophenone 0.5%, 1,2-hexanediol 0.2%, Zeasat TM0.8% and water balance;
[0136] The preparation method comprises the following steps: mixing p-hydroxyacetophenone and butylene glycol at 75° C. to obtain a first preform; mixing water, carbomer, ammonium acryloyldimethyltaurate / VP copolymer, glycerol, tremella polysaccharide, and allantoin at 80° C.; cooling to 75° C. and mixing with HAMIN-C, argania spinosa kernel oil, triethylhexanoin, shea butter, tocopherol acetate, hexyldecyl myristoyl methylaminopropionate, and bisabolol; cooling to 65° C. and mixing with PC 2000; cooling to 50° C. and mixing with 1,2-hexanediol, the first preform, and Zeastatin. TM The mixture is mixed, cooled to 40°C, and mixed with biosaccharide gum-1, oat beta-glucan, citrus peel extract, ascorbyl tetraisopalmitate, coenzyme Q10, microalgae skin brightening agent, nonapeptide-1, kava extract, and plant allergy-relieving agent to obtain the mixture.
[0137] Preparation Example 9
[0138] The preparation example provides a facial cream, the composition of which is: carbomer 0.15%, ammonium acryloyldimethyltaurate / VP copolymer 0.4%, HAMIN-C 3.5%, argania spinosa kernel oil 0.5%, triethylhexanoin 2%, shea butter 1%, tocopherol acetate 1.5%, hexyldecyl myristoyl methylaminopropionate 3%, butylene glycol 2%, glycerol 4%, tremella polysaccharide 0.08%, allantoin 0.05%, oat beta glucan 2%, biosaccharide gum-1 4%, citrus peel extract 0.5%, ascorbyl tetraisopalmitate 1%, coenzyme Q10 0.1%, microalgae skin lightening agent 0.5%, nonapeptide-1 0.5%, kava extract 0.3%, plant allergy-relieving agent 3%, bisabolol 0.1%, PC 2000 0.07%, p-hydroxyacetophenone 0.2%, 1,2-hexanediol 0.6%, Zeastat TM 0.5% and water balance;
[0139] The preparation method comprises the following steps: mixing p-hydroxyacetophenone and butylene glycol at 70° C. to obtain a first preform; mixing water, carbomer, ammonium acryloyldimethyltaurate / VP copolymer, glycerol, tremella polysaccharide, and allantoin at 75° C.; cooling to 70° C. and mixing with HAMIN-C, argania spinosa kernel oil, triethylhexanoin, shea butter, tocopherol acetate, hexyldecyl myristoyl methylaminopropionate, and bisabolol; cooling to 60° C. and mixing with PC 2000; cooling to 45° C. and mixing with 1,2-hexanediol, the first preform, and Zeastatin. TMMix, cool to 30°C, and mix with biosaccharide gum-1, oat beta-glucan, citrus peel extract, ascorbyl tetraisopalmitate, coenzyme Q10, microalgae skin brightening agent, nonapeptide-1, kava extract, and plant allergy-relieving agent to obtain.
[0140] Comparative Preparation Example 1
[0141] This comparative preparation example provides a skin care essence, which differs from Preparation Example 1 only in that it does not contain biosaccharide gum-4, and its reduced mass is proportionally distributed to the masses of oat β-glucan, Nanopro CERA II, plant allergens and coenzyme Q10, while other ingredients and contents remain unchanged.
[0142] The preparation method is as in Preparation Example 1.
[0143] Comparative Preparation Example 2
[0144] This comparative preparation example provides a skin care essence, which differs from Preparation Example 1 only in that the skin care essence does not contain oat β-glucan, and its reduced mass is proportionally distributed to the masses of biosaccharide gum-4, Nanopro CERA II, plant allergens and coenzyme Q10, and other ingredients and contents remain unchanged.
[0145] The preparation method is as in Preparation Example 1.
[0146] Comparative Preparation Example 3
[0147] This comparative preparation example provides a skin care essence, which differs from Preparation Example 1 only in that the skin care essence does not contain Nanopro CERA II, and its reduced mass is proportionally distributed to the mass of biosaccharide gum-4, coenzyme Q10, plant allergens and oat β-glucan, and other ingredients and contents remain unchanged.
[0148] The preparation method is as in Preparation Example 1.
[0149] Comparative Preparation Example 4
[0150] This comparative preparation example provides a skin care essence, which differs from Preparation Example 1 only in that the skin care essence does not contain a plant allergen, and its reduced mass is proportionally distributed to the mass of biosaccharide gum-4, Nanopro CERA II, coenzyme Q10 and oat β-glucan, while other ingredients and contents remain unchanged.
[0151] The preparation method is as in Preparation Example 1.
[0152] Comparative Preparation Example 5
[0153] This comparative preparation example provides a skin care essence, which differs from Preparation Example 1 only in that the skin care essence does not contain coenzyme Q10, and its reduced mass is proportionally distributed to the mass of biosaccharide gum-4, Nanopro CERA II, plant allergens and oat β-glucan, and other ingredients and contents remain unchanged.
[0154] The preparation method is as in Preparation Example 1.
[0155] Comparative Preparation Example 6
[0156] This comparative preparation example provides a facial mask, which differs from Preparation Example 4 only in that the facial mask does not contain North American witch hazel extract, and its reduced mass is proportionally distributed to the mass of mung bean fermentation liquid and plant allergy-relieving agent, and other ingredients and contents remain unchanged.
[0157] The preparation method is as in Preparation Example 4.
[0158] Comparative Preparation Example 7
[0159] This comparative preparation example provides a facial mask, which differs from Preparation Example 4 only in that the facial mask does not contain mung bean fermentation liquid, and its reduced mass is proportionally distributed to the mass of North American witch hazel extract and plant allergy-relieving agent, and other ingredients and contents remain unchanged.
[0160] The preparation method is as in Preparation Example 4.
[0161] Comparative Preparation Example 8
[0162] This comparative preparation example provides a facial mask, which differs from Preparation Example 4 only in that the facial mask does not contain a plant allergen, and its reduced mass is proportionally distributed to the mass of the North American witch hazel extract and the mung bean fermentation liquid, and the other ingredients and contents remain unchanged.
[0163] The preparation method is as in Preparation Example 4.
[0164] Comparative Preparation Example 9
[0165] This comparative preparation example provides a facial cream, which differs from Preparation Example 7 only in that the facial cream does not contain citrus peel extract, and its reduced mass is proportionally distributed to the masses of ascorbyl tetraisopalmitate, microalgae skin lightening agent, nonapeptide-1 and coenzyme Q10, and the other ingredients and contents remain unchanged.
[0166] The preparation method is similar to that of Preparation Example 7.
[0167] Comparative Preparation Example 10
[0168] This comparative preparation example provides a facial cream, which differs from Preparation Example 7 only in that the facial cream does not contain ascorbyl tetraisopalmitate, and its reduced mass is proportionally distributed to the mass of citrus peel extract, microalgae skin lightening agent, nonapeptide-1 and coenzyme Q10, and the other ingredients and contents remain unchanged.
[0169] The preparation method is similar to that of Preparation Example 7.
[0170] Comparative Preparation Example 11
[0171] This comparative preparation example provides a facial cream, which differs from Preparation Example 7 only in that the facial cream does not contain coenzyme Q10, and its reduced mass is proportionally distributed to the mass of citrus peel extract, microalgae skin lightening agent, nonapeptide-1 and ascorbyl tetraisopalmitate, and the other ingredients and contents remain unchanged.
[0172] The preparation method is similar to that of Preparation Example 7.
[0173] Comparative Preparation Example 12
[0174] This comparative preparation example provides a facial cream, which differs from Preparation Example 7 only in that the facial cream does not contain nonapeptide-1, and its reduced mass is proportionally distributed to the mass of citrus peel extract, microalgae skin lightening agent, coenzyme Q10 and ascorbyl tetraisopalmitate, and the other ingredients and contents remain unchanged.
[0175] The preparation method is similar to that of Preparation Example 7.
[0176] Comparative Preparation Example 13
[0177] This comparative preparation example provides a facial cream, which differs from Preparation Example 7 only in that the facial cream does not contain a microalgae skin lightening agent, and its reduced mass is proportionally distributed to the mass of citrus peel extract, coenzyme Q10, nonapeptide-1 and ascorbyl tetraisopalmitate, while the other ingredients and contents remain unchanged.
[0178] The preparation method is similar to that of Preparation Example 7.
[0179] Example 1
[0180] This embodiment provides a cosmetic composition, which includes a skin care essence, a facial mask, and a facial cream.
[0181] The composition, content and preparation method of the skin care essence are the same as those in Preparation Example 1, the composition, content and preparation method of the facial mask are the same as those in Preparation Example 4, and the composition, content and preparation method of the facial cream are the same as those in Preparation Example 7.
[0182] Example 2
[0183] This embodiment provides a cosmetic composition, which includes a skin care essence, a facial mask, and a facial cream.
[0184] The composition, content and preparation method of the skin care essence are the same as those in Preparation Example 2, the composition, content and preparation method of the facial mask are the same as those in Preparation Example 5, and the composition, content and preparation method of the facial cream are the same as those in Preparation Example 8.
[0185] Example 3
[0186] This embodiment provides a cosmetic composition, which includes a skin care essence, a facial mask, and a facial cream.
[0187] The composition, content and preparation method of the skin care essence are the same as those in Preparation Example 3, the composition, content and preparation method of the facial mask are the same as those in Preparation Example 6, and the composition, content and preparation method of the facial cream are the same as those in Preparation Example 9.
[0188] Example 4
[0189] This embodiment provides a cosmetic composition, which includes skin care water, massage honey, skin care essence, facial mask, and facial cream;
[0190] The skin care water comprises: 0.06% carbomer, 3% oat beta-glucan, 0.3% hydroxyethyl urea, 0.5% biosaccharide gum-1, 0.06% tremella polysaccharide, 0.01% Aqua-mix, 0.05% adenosine, 0.05% carnosine, 1% kava extract, 0.02% PC 2000, 0.8% 1,2-pentanediol, 0.12% methyl ester, 1% HL-02PLUS and the balance water;
[0191] The massage honey comprises: AT 100P 0.8%, carbomer 0.12%, trehalose 0.3%, betaine 0.3%, glycerol 26%, sodium hyaluronate 0.05%, tocopherol acetate 0.8%, bridge fruit oil 0.1%, lemon peel extract 0.3%, resveratrol fermentation 0.3%, coenzyme Q10 0.3%, kava extract 0.5%, plant allergy reliever 1.2%, PC 2000 0.07%, 1,2-hexanediol 0.3%, HL-01 0.6% and the balance of water;
[0192] The preparation method of the skin care water comprises: mixing water, carbomer, adenosine, methyl ester, and Tremella polysaccharide at 78° C., keeping the temperature for 8 minutes, cooling to 63° C. and mixing with PC 2000, cooling to 48° C. and mixing with 1,2-pentanediol and HL-02PLUS, cooling to 35° C. and mixing with oat beta-glucan, hydroxyethyl urea, biosaccharide gum-1, AQUA-MIX, carnosine, and kava extract to obtain the skin care water;
[0193] The preparation method of the massage honey comprises: mixing water, carbomer, trehalose, betaine, sodium hyaluronate and glycerin at 78°C, keeping the temperature for 8 minutes, cooling to 63°C and mixing with PC 2000, AT 100P, tocopherol acetate and bridge fruit oil, cooling to 48°C and mixing with HL-01 and 1,2-hexanediol, cooling to 35°C and mixing with resveratrol fermentation product, lemon peel extract, kava extract, plant allergy reliever and coenzyme Q10 to obtain the massage honey.
[0194] The composition, content and preparation method of the skin care essence are the same as those in Preparation Example 1, the composition, content and preparation method of the facial mask are the same as those in Preparation Example 4, and the composition, content and preparation method of the facial cream are the same as those in Preparation Example 7.
[0195] Example 5
[0196] This embodiment provides a cosmetic composition, which includes skin care water, massage honey, skin care essence, facial mask, and facial cream;
[0197] The skin care water comprises: carbomer 0.1%, oat beta-glucan 1%, hydroxyethyl urea 0.5%, biosaccharide gum-13%, tremella polysaccharide 0.03%, AQUA-MIX 0.1%, adenosine 0.1%, carnosine 0.2%, kava extract 0.5%, PC20000.005%, 1,2-pentanediol 1.2%, methyl ester 0.15%, HL-02PLUS 0.8% and the balance of water;
[0198] The massage honey comprises: AT 100P 1.4%, carbomer 0.05%, trehalose 1%, betaine 1%, glycerin 15%, sodium hyaluronate 0.1%, tocopherol acetate 0.5%, bridge fruit oil 0.3%, lemon peel extract 1%, resveratrol fermentation 0.1%, coenzyme Q10 0.1%, kava extract 1%, plant allergy reliever 0.5%, PC 20000 0.02%, 1,2-hexanediol 0.6%, HL-01 0.5% and the balance of water;
[0199] The preparation method of the skin care water comprises: mixing water, carbomer, adenosine, methyl ester, and Tremella polysaccharide at 80° C., keeping the temperature for 5 minutes, cooling to 65° C. and mixing with PC 2000, cooling to 50° C. and mixing with 1,2-pentanediol and HL-02PLUS, cooling to 40° C. and mixing with oat beta-glucan, hydroxyethyl urea, biosaccharide gum-1, AQUA-MIX, carnosine, and kava extract to obtain the skin care water;
[0200] The preparation method of the massage honey comprises: mixing water, carbomer, trehalose, betaine, sodium hyaluronate and glycerin at 80°C, keeping the temperature for 5 minutes, cooling to 65°C and mixing with PC 2000, AT 100P, tocopherol acetate and bridge fruit oil, cooling to 50°C and mixing with HL-01 and 1,2-hexanediol, cooling to 40°C and mixing with resveratrol fermentation product, lemon peel extract, kava extract, plant allergy reliever and coenzyme Q10 to obtain the massage honey.
[0201] The composition, content and preparation method of the skin care essence are the same as those in Preparation Example 2, the composition, content and preparation method of the facial mask are the same as those in Preparation Example 5, and the composition, content and preparation method of the facial cream are the same as those in Preparation Example 8.
[0202] Example 6
[0203] This embodiment provides a cosmetic composition, which includes skin care water, massage honey, skin care essence, facial mask, and facial cream;
[0204] The skin care water comprises: carbomer 0.03%, oat beta-glucan 4%, hydroxyethyl urea 0.2%, biosaccharide gum-1 1%, tremella polysaccharide 0.1%, AQUA-MIX 0.05%, adenosine 0.02%, carnosine 0.1%, kava extract 2%, PC 20000.005%, 1,2-pentanediol 0.5%, methyl ester 0.1%, HL-02PLUS 1.2% and the balance of water;
[0205] The massage honey comprises: AT 100P 0.5%, carbomer 0.2%, trehalose 1%, betaine 0.1%, glycerin 35%, sodium hyaluronate 0.01%, tocopherol acetate 1%, bridge fruit oil 0.05%, lemon peel extract 0.1%, resveratrol fermentation 1%, coenzyme Q10 0.6%, kava extract 0.3%, plant allergy reliever 2%, PC 20000 0.1%, 1,2-hexanediol 0.2%, HL-01 1% and the balance of water;
[0206] The preparation method of the skin care water comprises: mixing water, carbomer, adenosine, methyl ester, and Tremella polysaccharide at 75° C., keeping the temperature for 10 minutes, cooling to 60° C. and mixing with PC 2000, cooling to 45° C. and mixing with 1,2-pentanediol and HL-02PLUS, cooling to 30° C. and mixing with oat beta-glucan, hydroxyethyl urea, biosaccharide gum-1, AQUA-MIX, carnosine, and kava extract to obtain the skin care water;
[0207] The preparation method of the massage honey comprises: mixing water, carbomer, trehalose, betaine, sodium hyaluronate and glycerin at 75°C, keeping the temperature for 10 minutes, cooling to 60°C and mixing with PC 2000, AT 100P, tocopherol acetate and bridge fruit oil, cooling to 45°C and mixing with HL-01 and 1,2-hexanediol, cooling to 30°C and mixing with resveratrol fermentation product, lemon peel extract, kava extract, plant allergy reliever and coenzyme Q10 to obtain the massage honey.
[0208] The composition, content and preparation method of the skin care essence are the same as those in Preparation Example 3, the composition, content and preparation method of the facial mask are the same as those in Preparation Example 6, and the composition, content and preparation method of the facial cream are the same as those in Preparation Example 9.
[0209] Comparative Example 1
[0210] This comparative example provides a cosmetic composition, which differs from Example 1 only in that it does not contain a facial mask, and the ingredients and contents of the facial cream and the skin care essence remain unchanged.
[0211] The preparation method is as in Example 1.
[0212] Comparative Example 2
[0213] This comparative example provides a cosmetic composition, which differs from Example 1 only in that it does not contain a facial cream, and the ingredients and contents of the facial mask and the skin care essence remain unchanged.
[0214] The preparation method is as in Example 1.
[0215] Comparative Example 3
[0216] This comparative example provides a cosmetic composition, which differs from Example 1 only in that it does not contain a skin care essence, and the ingredients and contents of the mask and the mask remain unchanged.
[0217] The preparation method is as in Example 1.
[0218] Test Example 1
[0219] Moisturizing effect test
[0220] Test samples: Preparation Examples 1-3 and Comparative Preparation Examples 1-5
[0221] (1) Recruit 80 volunteers aged 30 to 60 years old, female, with daily skin care habits, and meeting the inclusion and exclusion criteria of the "Technical Specifications for Safety of Cosmetics". The volunteers are randomly divided into 8 groups, and the same amount of the skin care products prepared in Preparation Examples 1-3 and Comparative Preparation Examples 1-5 are used respectively.
[0222] (2) The moisturizing effect of skin care products was measured using Delfin's MoistureMeterEpiD subcutaneous 0.5mm water content meter. The principle of using the capacitance method to measure the water content of the stratum corneum of human skin is based on the significant difference in the dielectric constants of water and other substances. According to the different water content of the stratum corneum of the skin, the measured capacitance value of the skin is different, and its parameters can represent the water content of the skin.
[0223] (3) Test process: The test area is the inner side of the forearms of both hands. No products (cosmetics or topical drugs) can be used on the test area for 3 days before the test, and the test area cannot come into contact with water for 3 hours before the test. Before the test, the subjects need to clean the inner side of the forearms of both hands. The cleaning method is to wipe it clean with dry tissue paper. Sit quietly in a laboratory with a temperature of 21±1℃ and 50±10%RH for 30 minutes, and do not drink water or beverages during this period. The subject's forearm is exposed and placed in the test state, and remains relaxed. After 30 minutes, the laboratory technician tests the initial value T0 of the subject's skin moisture content, and then instructs the subject to use the product, sit quietly in a laboratory with a temperature of 21±1℃ and 50±10%RH for 1 hour, and do not drink water or beverages during this period. After 1 hour, the subject's skin moisture content T1 is tested. The difference between the skin moisture content T1 and the initial value T0 of each group of subjects is calculated, and the difference before and after the subjects use the product is statistically analyzed to indicate the immediate moisturizing effect of the product. Then the subjects are instructed to use the product once in the morning and once in the evening, and the amount of product used by the subjects is equal. No other skin care products are used during this period. After 28 days, the subjects returned for a visit, wiped their forearms with dry tissues, and sat in a laboratory at a temperature of 20±1℃ and 50±10%RH for 30 minutes. They were not allowed to drink water or beverages during this period. Then the technicians tested the skin moisture content T2 of the subjects, calculated the difference between the skin moisture content T2 and the initial value T0, and statistically analyzed the difference before and after use for each group of subjects to represent the long-term moisturizing effect of the product. If the data is normally distributed, the t-test method is used for statistical analysis; if the data is non-normally distributed, the rank sum test method is used for statistical analysis. The statistical methods all use two-tailed tests, and the test level α=0.05. The test results of instant moisturizing and long-term moisturizing effects are shown in Table 1:
[0224] Table 1
[0225]
[0226]
[0227] From the data in Table 1, it can be seen that biosaccharide gum-4, oat β-glucan, plant allergens, coenzyme Q10 and NanoproCERA II have a certain synergistic effect in improving the moisturizing effect of skin care essence.
[0228] Test Example 2
[0229] Soothing effect test
[0230] Test samples: Preparation Examples 1-3 and Comparative Preparation Examples 1-5
[0231] 80 volunteers with sensitive skin were selected as research subjects, including 40 males and 40 females. The volunteers were randomly divided into 8 groups, each with 10 people, 5 males and 5 females. Each group tried the skin care essence prepared by Preparation Examples 1-3 and Comparative Preparation Examples 1-5 in equal amounts. The subjects were not allowed to make up or use skin care products on the morning of the test day. After cleaning the facial skin with clean water, they waited for 30 minutes in a constant temperature and humidity room, and then used VISIA-CR to take a photo of the volunteer's face from the front, and IPP software analyzed the a value of the red component image. Then, 10% lactic acid was applied to the nasolabial groove on either side of the volunteer at room temperature. After applying for 5 minutes, the skin care essence of Preparation Examples 1-3 and Comparative Preparation Examples 1-5 was used respectively. After 15 minutes of use, VISIA-CR was used to take a photo of the volunteer's face from the front again, and IPP software analyzed the a value of the red component image. The changes in a value before and after using the product were compared (the lower the a value, the lower the degree of skin redness), and the volunteers were asked to evaluate the use experience. The specific test results are shown in Table 2.
[0232] Table 2
[0233]
[0234]
[0235] From the data in Table 2, it can be seen that biosaccharide gum-4, oat β-glucan, plant allergens, coenzyme Q10 and NanoproCERA II have a certain synergistic effect in improving the soothing effect of skin care essence.
[0236] Test Example 3
[0237] Anti-inflammatory efficacy test
[0238] Test samples: Preparation Examples 4-6 and Comparative Preparation Examples 6-8
[0239] The anti-inflammatory effect of the mask was tested according to the following anti-inflammatory ability test method, and the test results are shown in Table 3.
[0240] The principle of this test is: keratinocytes are immune active cells present in the epidermis, which can secrete at least 9 interleukins (IL), which play an important role in lymphocyte proliferation, activation of inflammatory cells, etc. Studies have found that IL-6 secreted by keratinocytes after ultraviolet (UVB) radiation can promote fibroblasts to produce extracellular matrix metalloproteinases (NMPs), which can lead to collagen degradation and damage to the extracellular matrix, resulting in skin aging. In addition, UVB can induce keratinocytes to secrete more IL-8, promote the local aggregation of neutrophils in the skin, induce subsequent inflammatory reactions, and further affect the immune function of the skin.
[0241] Anti-inflammatory ability test method:
[0242] (1) HaCat cells were grown at a density of 3.0×10 5 pcs / mL / well were inoculated into 12-well plates and placed in an incubator for 18 h. The culture medium was MEM medium containing 10% FBS stored at 4°C for 2 weeks.
[0243] (2) The samples prepared in Preparation Examples 4-6 and Comparative Preparation Examples 6-8 were respectively prepared with complete culture medium (MEM + 10% FBS) to prepare a 5.0% test sample solution by volume;
[0244] (3) Remove the culture plate, discard the original culture medium in the well, add 1 mL of the test sample solution to each well, and stimulate with lipopolysaccharide LPS (10 μg / mL, final concentration). Set up a model group and a blank control group at the same time. The model group was stimulated with lipopolysaccharide LPS (10 μg / mL, final concentration) without adding the test sample solution, and the blank control group was stimulated with 1 mL of complete culture medium (MEM+10% FBS) without lipopolysaccharide LPS stimulation, and cultured for 24±1h;
[0245] (4) Remove the original culture medium, add 1 mL of fresh culture medium, continue to culture for 24 hours, collect the supernatant, and use ELISA kit to determine cytokines. The test conditions are temperature 37°C, humidity 90%, and 5% CO2 concentration. Data analysis: Statistical analysis of the anti-inflammatory activity of each group of test sample solutions on inflammatory factors (IL-6, IL-8). If the data is normally distributed, the t-test method is used for statistical analysis; if the data is non-normally distributed, the rank sum test method is used for statistical analysis. The statistical methods all use two-tailed tests, and the test level α=0.05.
[0246] The experimental results are shown in Table 3 below (the blank control group test results are the contents of IL-6 and IL-8 inflammatory factors in normal cells, and the model group test results are the contents of IL-6 and IL-8 inflammatory factors after keratinocytes were stimulated by lipopolysaccharide):
[0247] Table 3
[0248]
[0249] It can be seen from the data in Table 3 that the witch hazel extract, mung bean fermentation liquid and plant allergy-relieving agent have a certain synergistic effect in improving the anti-inflammatory effect of the product.
[0250] Test Example 4
[0251] Antioxidant efficacy test
[0252] Test samples: Preparation Examples 7-9 and Comparative Preparation Examples 9-13
[0253] DPPH test method:
[0254] (1) Preparation of DPPH-ethanol solution: Weigh 12 mg of 1,1-diphenyl-2-trinitrobenzene phenoxylate (Macklin, purity > 96%) and dissolve it in anhydrous ethanol. Add anhydrous ethanol to a 250 mL brown volumetric flask and use it immediately after preparation.
[0255] (2) Sampling test: 1 mL of the composition of Preparation Examples 7-9 and Comparative Preparation Examples 9-13 and 1 mL of DPPH-ethanol solution were respectively transferred into a 5 mL brown volumetric flask, 3 mL of anhydrous ethanol was added, and the mixture was shaken well. After a period of reaction in the dark, the absorbance was measured at a wavelength of 517 nm using a cuvette;
[0256] (3) Data analysis: The calculation formula of free radical scavenging rate (Y) is:
[0257] Y(%)=[l-(AB) / (CD)]×100%
[0258] Wherein: A is the absorbance value after adding 1 mL of the samples of Preparation Examples 7-9 and Comparative Preparation Examples 9-13 and reacting with 1 mL of DPPH-ethanol solution in step (2);
[0259] B—absorbance value of adding 1 mL of ultrapure aqueous solution of the samples of Preparation Examples 7-9 and Comparative Preparation Examples 9-13, i.e., replacing 1 mL of ultrapure water with 1 mL of DPPH-ethanol solution in step (2);
[0260] C—absorbance value of 1 mL of DPPH-ethanol solution without adding the test sample, i.e., 1 mL of the sample solution of Preparation Examples 7-9 and Comparative Preparation Examples 9-13 in step (2) is replaced with 1 mL of ultrapure water;
[0261] D—The absorbance value of DPPH-ethanol solution without adding test sample, that is, the absorbance value after mixing 2mL ultrapure water and 3mL anhydrous ethanol.
[0262] Table 4
[0263] Group Free radical scavenging rate (%) Preparation Example 7 86.5 Preparation Example 8 82.6 Preparation Example 9 83.7 Comparative Preparation Example 9 75.8 Comparative Preparation Example 10 53.6 Comparative Preparation Example 11 65.4 Comparative Preparation Example 12 68.3 Comparative Preparation Example 13 70.9
[0264] From the data in Table 4, it can be seen that citrus peel extract, coenzyme Q10, ascorbyl tetraisopalmitate, microalgae skin lightening agent and nonapeptide-1 have a certain synergistic effect in improving the antioxidant effect.
[0265] Test Example 5
[0266] Tyrosinase inhibition test
[0267] Test samples: Preparation Examples 7-9 and Comparative Preparation Examples 9-13
[0268] 1.1 Sample preparation
[0269] The sample was prepared at a ratio of 0.45 mg sample to 1 mL serum-free culture medium;
[0270] 1.2 Cell culture
[0271] Mouse B16 melanoma cells were grown to a confluent state, digested with trypsin-EDTA for 5 minutes, and then dispersed by blowing. The cell suspension was aspirated into a centrifuge tube and centrifuged at 1000r / min for 5 minutes. The supernatant was discarded and culture medium was added to obtain a cell suspension. The cell suspension was diluted to a certain concentration with culture medium. B16 cells in the logarithmic growth phase were inoculated in a 96-well plate at a cell density of 7×10 4 CFU / mL, 100 μL per well, mark the top cover of the cell plate after laying the plate, and culture in the incubator for 24 hours.
[0272] After 24 hours of culture, the cell plate was carefully aspirated with a pipette to remove the supernatant and divided into a blank group, a positive control group, and a sample group. The prepared sample was added to the sample group, the culture solution containing α-arbutin was added to the positive control group, and the serum-free culture medium without drugs was added to the blank group. The addition amount was 100 μL / well, and 4 replicates were made for each concentration. After addition, the cells were placed in an incubator for 72 hours of culture.
[0273] 1.3 Determination of intracellular tyrosinase inhibition rate
[0274] After incubation for 72 hours, the supernatant was discarded, 150 μL of 1% TritonX-100 solution was added to each well, and the cells were quickly frozen at -80°C for 30 minutes, then thawed at room temperature to completely rupture the cells, and 60 μL of 0.5% L-DOPA solution was added after preheating at 37°C for 5 minutes, and reacted at 37°C for 2 hours. The absorbance (OD) value was measured at 490 nm on a microplate reader. The tyrosinase activity inhibition rate was calculated.
[0275] Tyrosinase activity inhibition rate (%) = (1-average absorbance value of sample / average absorbance value of blank) × 100%.
[0276] Table 5
[0277] Group Tyrosinase inhibition rate (%) Preparation Example 7 38.12 Preparation Example 8 36.32 Preparation Example 9 35.42 Comparative Preparation Example 9 18.63 Comparative Preparation Example 10 17.52 Comparative Preparation Example 11 15.46 Comparative Preparation Example 12 18.57 Comparative Preparation Example 13 21.35
[0278] From the data in Table 5, it can be seen that citrus peel extract, coenzyme Q10, ascorbyl tetraisopalmitate, microalgae skin lightening agent and nonapeptide-1 have a certain synergistic effect in improving the whitening effect.
[0279] Test Example 6
[0280] The whitening effect of Examples 1-6 and Comparative Examples 1-3 was tested, and the testing method was as follows:
[0281] (1) Recruit 90 volunteers aged 18-60 years old, female or male, with daily skin care habits, and meet the inclusion and exclusion criteria of the "Technical Specifications for Safety of Cosmetics". The volunteers were randomly divided into 9 groups, and the package products prepared by Examples 1-6 and Comparative Examples 1-3 were used respectively, and the amount of each product used was equal, wherein when the package product described in Comparative Example 1 was used, an equal amount of the Tianyan Nutrition Mask of Guangdong Basona Biotechnology Co., Ltd. was also used, when the package product described in Comparative Example 2 was used, an equal amount of the Tianyan Nutrition Cream of Guangdong Basona Biotechnology Co., Ltd. was also used, and when the package product described in Comparative Example 3 was used, an equal amount of the Tianyan Nutrition Essence Water of Guangdong Basona Biotechnology Co., Ltd. was also used.
[0282] (2) The whitening effect of skin care products is measured using a skin colorimeter and a skin melanin detector. A skin colorimeter is an instrument that can measure the L*a*b* color space data established by the International Commission on Illumination (CIE). The parameters of human skin color are characterized by measuring the skin L*a*b* color space data using a skin colorimeter or a reflectance spectrophotometer. The calculation formula is as follows:
[0283]
[0284] The skin melanin detector is an instrument that detects the skin MI value based on the principle of spectral absorption.
[0285] (3) Test process: The test area is the face. No products (cosmetics or topical drugs) can be used on the test area for 3 days before the test, and the test area cannot come into contact with water for 3 hours before the test. Before the test, the subjects need to clean their facial skin uniformly and sit quietly in a laboratory at a temperature of 21±1℃ and 50±10%RH for 30 minutes. During this period, they cannot drink water or beverages. The subjects remain relaxed. After 30 minutes, the laboratory technician will test the subjects and then guide the subjects to use the products. The same evaluation and test will be conducted again in the 4th and 8th weeks. The L*, a*, and b* values of the skin in the test area are measured with a skin colorimeter. Each test area is tested three times, and the ITA° value is recorded and calculated. The larger the ITA° value of the test skin area, the lighter the skin color, and vice versa. The MI value of the skin in the test area is measured with a skin melanin tester. Each test area is tested three times and recorded; the smaller the MI value of the test area, the lighter the skin color, and vice versa. If the data is normally distributed, the t-test method is used for statistical analysis; if the data is non-normally distributed, the rank sum test method is used for statistical analysis. The statistical methods all use two-tailed tests, and the test level α = 0.05. The whitening effect test results are shown in the table:
[0286] Table 6
[0287]
[0288] From the data in Table 6, it can be seen that in the cosmetic composition, skin care essence, facial mask and facial cream have a certain synergistic effect in improving the whitening effect. And the skin care essence, facial mask and facial cream are more effective when used with skin care water and massage honey.
[0289] The applicant declares that the present invention uses the above-mentioned embodiments to illustrate a mild cosmetic composition with whitening and moisturizing effects and a preparation method thereof, but the present invention is not limited to the above-mentioned embodiments, that is, it does not mean that the present invention must rely on the above-mentioned embodiments to be implemented. Those skilled in the art should understand that any improvement of the present invention, equivalent replacement of various raw materials of the product of the present invention, addition of auxiliary ingredients, selection of specific methods, etc., all fall within the protection scope and disclosure scope of the present invention.
[0290] The preferred embodiments of the present invention are described in detail above. However, the present invention is not limited to the specific details in the above embodiments. Within the technical concept of the present invention, a variety of simple modifications can be made to the technical solution of the present invention, and these simple modifications all belong to the protection scope of the present invention.
[0291] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, the present invention will not further describe various possible combinations.
Claims
1. A mild set of products with whitening and moisturizing effects, characterized in that: The mild whitening and moisturizing product set includes skin care essence, facial mask and facial cream; The ingredients of the skin care essence include ammonium acryloyldimethyltaurate / VP copolymer, sodium polyacrylate, butylene glycol, glycerin, trehalose, Tremella fuciformis polysaccharide, AQUA-MIX, oat beta-glucan, biosaccharide gum-4, Nanopro CERA II, plant soothing agent, coenzyme Q10, BioStine HP, nonapeptide-1, parahydroxyacetophenone, 1,2-hexanediol and Zeasat™; The ingredients of the mask include carbomer, xanthan gum, ammonium acryloyldimethyltaurate / VP copolymer, EDTA-2Na, betaine, butylene glycol, methylpropanediol, witch hazel extract, mung bean fermentation liquid, plant allergens, carnosine, active ingredients, PC 2000, 1,2-pentanediol, 1,2-hexanediol and Zeasat™; the active ingredients include diethoxyethyl succinate and water-soluble ceramide; The ingredients of the cream include carbomer, ammonium acryloyldimethyltaurate / VP copolymer, HAMIN-C, argania spinosa kernel oil, triethylhexanoin, shea butter, tocopheryl acetate, hexyldecyl myristoyl methylaminopropionate, butylene glycol, glycerin, tremella polysaccharide, allantoin, oat beta-glucan, biosaccharide gum-1, citrus peel extract, ascorbyl tetraisopalmitate, coenzyme Q10, microalgae brightening agent, nonapeptide-1, soothing ingredient, PC 2000, parahydroxyacetophenone, 1,2-hexanediol and Zeastat™; the soothing ingredient includes kava extract, plant soothing agent and bisabolol; The plant allergy-relieving agent includes centella asiatica extract, knotweed root extract, scutellaria root extract, tea extract, licorice extract, chamomile flower extract and rosemary extract; The Nanopro CERA II includes ceramide NS / ceramide NG, lecithin, tocopheryl acetate, octyldodecanol and glycerin; The microalgae skin lightening agent includes 1,3-propylene glycol, lutein, lecithin, sodium ascorbate and tocopherol.
2. The mild whitening and moisturizing product set according to claim 1, characterized in that: The mild whitening and moisturizing product set also includes massage honey; The massage honey comprises ingredients including AT 100P, carbomer, trehalose, betaine, glycerin, sodium hyaluronate, tocopheryl acetate, bridge fruit oil, lemon peel extract, resveratrol fermentation, coenzyme Q10, kava extract, plant allergy reliever, PC 2000, 1,2-hexanediol and HL-01.
3. The mild whitening and moisturizing product set according to claim 1 or 2, characterized in that: The skin care essence comprises, by weight percentage, 2-5% of biosaccharide gum-4, 1-3% of oat beta-glucan, 0.1-2% of plant allergy reliever, 0.1-0.5% of coenzyme Q10 and 0.5-2% of Nanopro CERA II.
4. The mild whitening and moisturizing product set according to claim 1 or 2, characterized in that: The facial mask comprises, by weight percentage, 2-5% of witch hazel extract, 0.3-1% of mung bean fermentation liquid, 0.3-1.5% of plant allergy-relieving agent and 0.5-2% of active ingredients.
5. The mild whitening and moisturizing product set according to claim 1 or 2, characterized in that: The facial cream comprises, by weight percentage, 0.5-2% of citrus peel extract, 0.1-0.5% of coenzyme Q10, 0.3-2% of ascorbyl tetraisopalmitate, 0.3-1.5% of microalgae skin lightening agent, 1-100 ppm of nonapeptide-1 and 0.8-4.5% of soothing ingredients.
6. The mild whitening and moisturizing product set according to claim 2, characterized in that: The massage honey comprises, by weight percentage, 0.1-1% of resveratrol fermentation product, 0.1-1% of lemon peel extract, 0.1-0.6% of coenzyme Q10, 0.3-1% of kava extract and 0.5-2% of plant allergy reliever.
7. The method for preparing the mild whitening and moisturizing package product according to any one of claims 1 to 6, characterized in that: The preparation method comprises: physically mixing the raw materials for preparing the skin care essence, the facial mask and the facial cream respectively to obtain the skin care essence, the facial mask and the facial cream.
8. The method for preparing the mild whitening and moisturizing package product according to claim 7, characterized in that: The preparation raw materials also include preparation raw materials for massage honey.
9. The method for preparing the mild package product with whitening and moisturizing effects according to claim 7, characterized in that: In the preparation method of the skin care essence, the mixing temperature of water, biosaccharide gum-4, oat beta-glucan, plant allergen, coenzyme Q10 and Nanopro CERA II is below 40°C.
10. The method for preparing the mild package product with whitening and moisturizing effects according to claim 8, characterized in that: In the preparation method of the massage honey, the mixing temperature of water, resveratrol fermentation product, lemon peel extract, kava extract, plant allergy reliever and coenzyme Q10 is below 40°C.
11. The method for preparing the mild whitening and moisturizing package product according to claim 7, characterized in that: In the preparation method of the facial mask, the mixing temperature of water, witch hazel extract, mung bean fermentation liquid and plant allergy-relieving agent is below 40°C.
12. The method for preparing the mild whitening and moisturizing package product according to claim 7, characterized in that: In the preparation method of the facial cream, the mixing temperature of water, citrus peel extract, coenzyme Q10, ascorbyl tetraisopalmitate, microalgae skin lightening agent and nonapeptide-1 is below 40°C.
Citation Information
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