A developing embryo transplantation structure and a developing embryo transplantation method

By introducing a soft-hard composite design of reflectors and supports into the embryo transplant structure, clear imaging is achieved under ultrasound imaging, solving the safety hazards and low success rate problems of gas and liquid imaging in existing technologies, and improving the success rate of embryo transplantation and user experience.

CN116746996BActive Publication Date: 2025-09-16HANGZHOU DIAGENS BIOTECH CO LTD
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Patent Information

Application Number
CN202310882095.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-07-18
Publication Date
2025-09-16
Estimated Expiration
2043-07-18

AI Technical Summary

Technical Problem

During the embryo transfer process, existing technologies rely on gas and liquid visualization, resulting in low success rates and safety risks, poor user experience, and possible physical damage to the uterus.

Method used

A soft and hard composite embryo transplantation structure composed of a reflector and a support is used. The reflector is used to achieve clear imaging under ultrasound imaging, reducing dependence on gas and liquid, and the support is used to assist the operation, reducing surgical difficulty and physical damage.

Benefits of technology

It improves the success rate of embryo transplantation, reduces stimulation to the uterus, enhances user experience, and simplifies the production process.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention discloses a developing embryo transplantation structure and a developing embryo transplantation method, belonging to the technical field of embryo transplantation equipment. A developing embryo transplantation structure of the present invention is provided with a reflector on the transplantation section. The reflector enables the embryo transplantation structure to be clearly imaged under ultrasound imaging during transplantation, thereby getting rid of the dependence on the gas and liquid in the embryo transplantation tube, reducing the difficulty of embryo loading and transplantation, and improving the success rate of embryo transplantation. The structure is simple, easy to produce, and the solution is feasible. When the developing embryo transplantation structure of the present invention is used for surgery, the doctor controls the insertion depth of the developing embryo transplantation structure according to the B-ultrasound imaging, assisting the doctor in intuitively identifying the position and distance of the developing embryo transplantation structure into the cervix, facilitating the doctor's surgical operation, reducing the difficulty of the operation, reducing the physical damage to the cervix or uterine cavity, and improving the success rate of embryo transplantation.
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Description

Technical Field

[0001] The invention relates to a developing embryo transplantation structure and a developing embryo transplantation method, belonging to the technical field of embryo transplantation equipment. Background Art

[0002] During embryo transfer, the embryo transfer structure needs to first inhale the embryo and then the culture medium and gas. The guide catheter is inserted into the cervix, the guide catheter establishes a transplant channel, and then the embryo transfer structure is inserted into the guide catheter, so that the embryo transfer structure enters the interior of the uterus. The embryo is then injected into the uterus for embryo transfer. The main purpose of inhaling culture medium and gas is to enable the transplant tube to be visualized under B-ultrasound, which facilitates the doctor to smoothly inject the embryo into the woman's uterus. However, inappropriate amounts of gas and liquid will affect the success rate of embryo transfer, and the inhaled liquid and gas will irritate the uterine cavity, posing certain safety risks and poor user experience, which is not conducive to its widespread use.

[0003] The information disclosed in this Background Art is only for understanding the background of the present inventive concept and therefore it may include information that does not constitute prior art. Summary of the Invention

[0004] In response to the above problem or one of the above problems, an object of the present invention is to provide a reflector, which enables the embryo transplant structure to be clearly imaged under ultrasonic imaging during transplantation, thereby getting rid of the dependence on gas and liquid in the embryo transfer tube, reducing the difficulty of embryo loading and transplantation, and improving the success rate of embryo transplantation. The structure is simple, easy to produce and manufacture, and the scheme is practical.

[0005] In response to the above problem or one of the above problems, the second object of the present invention is to provide a method for developing embryo transplantation that constructs a transplantation calculation model, a development calculation model, and a development simulation model to calculate the catheter data of the developing embryo transplantation structure and the brightness data required for transplantation of the developing embryo transplantation structure; then, based on the brightness data, the size data of the reflector is obtained to complete the transplantation simulation of the developing embryo, which is scientific, reasonable, and feasible.

[0006] In response to the above problem or one of the above problems, the third object of the present invention is to provide a developing embryo transplantation structure and a developing embryo transplantation method that can assist doctors in intuitively identifying the position and distance of the developing embryo transplantation structure entering the cervix, facilitate the doctor's surgical operation, reduce the difficulty of the operation, reduce the physical damage to the cervix or uterine cavity, and improve the success rate of embryo transplantation.

[0007] To achieve one of the above purposes, the first technical solution of the present invention is:

[0008] A developing embryo transplant structure comprises at least a transplant segment capable of being placed into a human body, a reflector capable of reflecting sound waves, and a support body capable of enhancing the structural strength of the transplant segment; the transplant segment is made of a soft material; the reflector is arranged on the transplant segment; the support body is made of a hard material; the transplant segment is partially sheathed on the support body, and the support body and the reflector are spaced apart to form a soft-hard composite developing structure in which the transplant segment is partially exposed.

[0009] The present invention provides a reflector on the embryo transplant structure. The reflector enables the embryo transplant structure to be clearly imaged under ultrasonic imaging during transplantation, thereby getting rid of the dependence on gas and liquid in the embryo transplant tube, reducing the difficulty of embryo loading and transplantation, improving the success rate of embryo transplantation, and effectively reducing stimulation to the uterus. Therefore, the present invention has high safety, good user experience, and is easy to promote and use. It also has a simple structure, is easy to produce and manufacture, and the solution is practical.

[0010] At the same time, the present invention is a soft and hard composite development structure, which uses a soft transplantation segment to enter the human body, which can effectively reduce the physical damage to the cervix or uterine cavity; at the same time, it uses a harder support body to support the transplantation segment, which is convenient for effective control of the position of the transplantation segment. The structure is simple, practical, and easy to promote and use.

[0011] Furthermore, the transplant section is partially sheathed on the support body, and the support body is spaced apart from the reflector so as to expose a sufficient length of the soft transplant section, thereby effectively reducing physical damage to the human body when the developed embryo transplant structure enters the human body.

[0012] Furthermore, when the developing embryo transplant structure of the present invention is used for surgery, the doctor controls the insertion depth of the developing embryo transplant structure according to the B-ultrasound development, which helps the doctor intuitively identify the position and distance of the developing embryo transplant structure entering the cervix, facilitates the doctor's surgical operation, reduces the difficulty of the operation, reduces the physical damage to the cervix or uterine cavity, and improves the success rate of embryo transplantation.

[0013] The soft material may be rubber or soft plastic or plastic material.

[0014] The hard material can be stainless steel, hard plastic, iron wire or wood.

[0015] As preferred technical measures:

[0016] The reflector is a developing tube, which is fixed to the front end of the transplant section, so that the doctor can accurately know the front end position of the developing embryo transplant structure and effectively avoid physical damage to the cervix or uterine cavity caused by the front end of the developing embryo transplant structure.

[0017] The transplant section is a transplant tube with a smooth outer surface. It is a soft tubular structure with a smooth outer surface, which can further reduce physical damage to the cervix or uterine cavity.

[0018] As preferred technical measures:

[0019] The developing tube is made of a material that is a fusion of tungsten metal powder and polymer polyurethane. Its outer surface is smooth and burr-free, further reducing physical damage to the cervix or uterine cavity.

[0020] Or / and, the developing tube is a through tube with an outer diameter of 0.9 mm, an inner diameter of 0.6 mm, and a length of 0.5 mm.

[0021] Since smaller tubes are less irritating to the human body, but too small a tube can affect embryo absorption, a 0.9mm x 0.6mm size is the most scientific and reasonable. Also, since the tube is black, it should be short, as this would make it difficult to observe embryo absorption under a microscope. However, if it is too short, it would affect ultrasound imaging, so a 0.5mm length meets the requirements.

[0022] As preferred technical measures:

[0023] The outer surface of the reflector is smooth or has an annular structure, an arc structure, a sheet structure or a block structure, and is fixed to the front end, the middle position, the front position or the rear position of the transplanted section.

[0024] Alternatively, the reflector includes a plurality of block structures that can be visualized under B-ultrasound; the block structures are evenly distributed on the transplanted section.

[0025] As preferred technical measures:

[0026] The developing tube is a through tube, the outer diameter of the tube is 1.8*A mm, the inner diameter of the tube is 1.2*A mm, and the length of the tube is A mm; 0.3≤A≤0.8.

[0027] As preferred technical measures:

[0028] The support tube is a support tube made of hard stainless steel and has limit scale lines on its surface to facilitate the movement of the transplant section made of soft material. If it is made entirely of soft material, when the transplant section is long, it is difficult to effectively position and accurately move it.

[0029] Or / and, the support member is a strip structure, an arc structure, a sheet structure, a mesh structure, or a frame structure, and is fixed on the inner or outer wall surface of the transplant segment.

[0030] Or / and, the end of the support body away from the transplant section is equipped with a connector for connecting a syringe.

[0031] As preferred technical measures:

[0032] The connector is fixed to the transplant section through a square body, and a protective cover is plugged into the connector through a truncated cone joint. When the transplant section is not in use or is being transported or stored, the protective cover can effectively protect the transplant section, prevent wear of the transplant section, and extend the service life of the transplant section.

[0033] The square body fixes the connector and the transplant section, which can effectively prevent the connector and the developing embryo transplant structure from rotating erroneously.

[0034] The protective cover is sleeved on the outside of the transplant section, and the length of the protective cover is Y;

[0035] The length of the transplanted segment is X;

[0036] The length of the reflector is h;

[0037] Y>(X+h), so as to fully cover and protect the transplanted section and the reflector;

[0038] The large end of the truncated cone joint is fixedly connected to the connector, and the small end thereof is plugged into the inner cavity of the protective cover, so that the protective cover can be quickly installed or removed. Since the inner cavity of the protective cover and the small end of the truncated cone joint are plugged and fixed, the inner cavity of the protective cover has an equal diameter structure, which can achieve effective plugging of the two, thereby effectively reducing the manufacturing cost of the protective cover.

[0039] The frustum joint is fixedly connected to the connecting head through a frustum body to achieve rapid assembly of the two.

[0040] To achieve one of the above purposes, the second technical solution of the present invention is:

[0041] A method for simulating embryo transplantation.

[0042] The following steps are involved:

[0043] The first step is to obtain the animal's uterine data;

[0044] The second step is to calculate the ductal data of the embryo implantation structure based on the uterine data using the pre-built implantation calculation model;

[0045] The catheter data at least includes tube shape information, tube length information and tube diameter information

[0046] The third step is to calculate the brightness data required for transplantation of the developed embryo transplant structure based on the catheter data of the developed embryo transplant structure through a pre-built development calculation model;

[0047] The fourth step is to use the pre-built development simulation model based on the brightness data to obtain the size data of the reflector and complete the transplantation simulation of the development embryo.

[0048] The present invention constructs a transplantation calculation model, a development calculation model, and a development simulation model to calculate the catheter data of the development embryo transplantation structure and the brightness data required for transplantation of the development embryo transplantation structure; then, based on the brightness data, the size data of the reflector is obtained to complete the transplantation simulation of the development embryo. The scheme is scientific, reasonable, and feasible.

[0049] Therefore, the present invention can be used to set a reflector that meets the requirements, so that the developed embryo transplant structure can be clearly imaged under ultrasound imaging, thereby getting rid of the dependence on gas and liquid in the embryo transplant tube, reducing the difficulty of embryo loading and transplantation, and improving the success rate of embryo transplantation. The structure is simple, easy to produce, and the solution is practical. As preferred technical measures:

[0050] The uterine data includes at least the insertion depth information of the developed embryo transfer structure and the position information of the cervix;

[0051] The catheter data at least includes tube shape information, tube length information and tube diameter information;

[0052] The size data of the reflector includes at least reflector distribution information, shape information, and reflective length information.

[0053] As preferred technical measures:

[0054] The tube shape is round tube, and the tube length is 500*A mm;

[0055] Pipe diameter information includes outer diameter and inner diameter;

[0056] The outer diameter of the tube is 1.8*A mm, and the inner diameter of the tube is 1.2*A mm;

[0057] Reflector distribution information includes ring distribution, sheet distribution, and block distribution;

[0058] The reflective length information is A mm;

[0059] 0.3≤A≤0.8.

[0060] Compared with the existing technical solutions, the present invention has the following beneficial effects:

[0061] The present invention provides a reflector on the embryo transplantation structure. The reflector enables the embryo transplantation structure to be clearly imaged under ultrasonic imaging during transplantation, thereby getting rid of the dependence on gas and liquid in the embryo transplantation tube, reducing the difficulty of embryo loading and transplantation, and improving the success rate of embryo transplantation. Therefore, the present invention has high safety, good user experience, and is easy to promote and use. In addition, it has a simple structure, is easy to produce and manufacture, and the solution is practical.

[0062] The present invention constructs a transplantation calculation model, a development calculation model, and a development simulation model to calculate the catheter data of the development embryo transplantation structure and the brightness data required for transplantation of the development embryo transplantation structure; then, based on the brightness data, the size data of the reflector is obtained to complete the transplantation simulation of the development embryo. The scheme is scientific, reasonable, and feasible.

[0063] Furthermore, when performing surgery using the developing embryo transplant structure of the present invention, the doctor controls the insertion depth of the developing embryo transplant structure based on B-ultrasound imaging, assisting the doctor in intuitively identifying the position and distance of the developing embryo transplant structure entering the cervix, facilitating the doctor's surgical operation, reducing the difficulty of the operation, reducing physical damage to the cervix or uterine cavity, and improving the success rate of embryo transplantation.

[0064] Furthermore, the transplantation section of the present invention is made of soft material, which can further reduce the physical damage to the cervix or uterine cavity, and has a simple structure and is practical. BRIEF DESCRIPTION OF THE DRAWINGS

[0065] Figure 1 This is a diagram showing the local structure of the embryo transplantation structure of the present invention;

[0066] Figure 2 A structural diagram of a developing tube according to the present invention;

[0067] Figure 3 for Figure 2 The structure shown is converted to a certain angle;

[0068] Figure 4 for Figure 3 The structure shown is converted to a certain angle;

[0069] Figure 5 This is a partial structural diagram of the developed embryo transplantation structure of the present invention;

[0070] Figure 6 A structural diagram of the embryo transplantation structure of the present invention (without protective cover);

[0071] Figure 7 A structural diagram of the embryo transplantation structure of the present invention (with a protective cover installed);

[0072] Figure 8 for Figure 7 A structural diagram showing a structure converted to a certain angle;

[0073] Figure 9 for Figure 6 A structural diagram showing a structure converted to a certain angle;

[0074] Figure 10 for Figure 8 A structural diagram showing a structure converted to a certain angle;

[0075] Figure 11 The figure is a flow chart of the embryo transfer simulation method of the present invention.

[0076] Description of reference numerals:

[0077] 1. Transplant tube; 2. Development tube; 3. Support tube; 4. Connector; 5. Cone joint; 51. Cone body; 6. Limit scale line; 7. Protective cover. DETAILED DESCRIPTION

[0078] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0079] On the contrary, the present invention covers any alternatives, modifications, equivalents, and solutions that fall within the spirit and scope of the present invention as defined by the claims. Furthermore, to facilitate a better understanding of the present invention, certain specific details are described in detail below in the detailed description of the present invention. Those skilled in the art will be able to fully understand the present invention without these details.

[0080] It should be noted that when two elements are "attached," the two elements may be directly connected or there may be an intermediate element. In contrast, when an element is referred to as being "directly on" another element, there are no intermediate elements. The terms "upper," "lower," and similar expressions used herein are for illustrative purposes only.

[0081] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one skilled in the art to which this invention pertains. The terms used herein are for the purpose of describing specific embodiments only and are not intended to limit the present invention. As used herein, the term "or / and" includes any and all combinations of one or more of the associated listed items.

[0082] like Figures 1-10 As shown, the first specific embodiment of the embryo transplantation structure of the present invention is:

[0083] A developing embryo transplant structure comprises at least a transplant segment capable of being placed into a human body, a reflector capable of reflecting sound waves, and a support body capable of enhancing the structural strength of the transplant segment; the transplant segment is made of a soft material; the reflector is arranged on the transplant segment; the support body is made of a hard material; the transplant segment is partially sheathed on the support body, and the support body and the reflector are spaced apart to form a soft-hard composite developing structure in which the transplant segment is partially exposed.

[0084] A specific embodiment of the reflector of the present invention:

[0085] The reflector is a developing tube 2, which is fixed to the front end of the implantation section. This allows the physician to accurately determine the front end position of the implantation structure, effectively preventing physical damage to the cervix or uterine cavity caused by the implantation structure. The developing tube 2 is manufactured from a fusion of tungsten metal powder and the polymer polyurethane, resulting in a smooth, burr-free surface that further minimizes physical damage to the cervix or uterine cavity.

[0086] The developing tube 2 is a through tube with an outer diameter of 0.9 mm, an inner diameter of 0.6 mm, and a length of 0.5 mm.

[0087] Since a smaller developing tube 2 has less irritation to the human body, but a smaller size would affect embryo absorption, a size of 0.9mm x 0.6mm is the most scientific and reasonable setting. Furthermore, since the developing tube 2 is black, the length of the developing tube 2 cannot be too long, as it would make it difficult to observe whether the embryo has been absorbed under a microscope. However, if it is too short, it would affect ultrasound imaging. Therefore, a length of 0.5mm meets the requirements.

[0088] A specific embodiment of the present invention in which a support body is added:

[0089] The transplant section is partially sheathed on the support body, and the support body is spaced apart from the reflector to expose a sufficient length of the soft transplant section, thereby reducing physical damage to the human body when the developed embryo transplant structure enters the human body.

[0090] The support body is a support tube 3, which is made of hard stainless steel and has limit scale lines 6 on its surface to facilitate the movement of the transplant section made of soft material. If it is made entirely of soft materials, when the transplant section is long, it is difficult to effectively position and accurately move it.

[0091] A specific embodiment of the present invention in which a connector 4 is added:

[0092] The end of the support body away from the transplant section is equipped with a connector 4 for connecting a syringe.

[0093] The connector 4 is fixed to the transplantation section via a square body. Fixing the connector 4 and the transplantation section via the square body can effectively prevent the connector 4 and the developing embryo transplantation structure from rotating erroneously.

[0094] A specific embodiment of the present invention in which a protective cover 7 is added:

[0095] The connector 4 is connected to a protective cover 7 through a truncated cone connector 5;

[0096] The protective cover 7 is sleeved on the outside of the transplant section, and the length of the protective cover 7 is Y;

[0097] The length of the transplanted segment is X;

[0098] The length of the reflector is h;

[0099] Y>(X+h), so as to fully cover and protect the transplanted section and the reflector;

[0100] The large end of the truncated cone joint 5 is fixedly connected to the connector 4, and the small end thereof is plugged into the inner cavity of the protective cover 7 so as to quickly install or remove the protective cover 7; since the inner cavity of the protective cover 7 is plugged and fixed with the small end of the truncated cone joint 5, the inner cavity of the protective cover 7 is an equal-diameter structure, which can effectively connect the two, thereby effectively reducing the manufacturing cost of the protective cover 7; the truncated cone joint 5 is fixed to the connector 4 through a truncated cone body 51 to achieve quick assembly of the two.

[0101] The second specific embodiment of the imaging embryo transplantation structure of the present invention:

[0102] A developing embryo transfer structure includes a connector 4, a limit mark 6, a support tube 3, a transplant tube 1, and a developing tube 2. The developing tube 2, which can be displayed under B-ultrasound, is embedded in the head of the transplant tube 1. When the transplant tube 1 enters the human body, medical staff can clearly see the position of the developing embryo transfer structure under B-ultrasound.

[0103] The developing tube 2 is made of a fusion of tungsten metal powder and a polymer material called polyurethane, manufactured using an extruder. It is then fused to the head of the graft tube 1 using a high-temperature welding process, resulting in a surface free of protrusions or uneven surfaces. The principle behind this invention's ability to image under B-ultrasound is that the density of tungsten differs significantly from that of the human body. The greater the difference in acoustic impedance, the stronger the reflected sound waves, resulting in a brighter image. The developing tube 2 has an outer diameter of 0.9 mm, an inner diameter of 0.6 mm, and a length of 0.5 mm.

[0104] A specific embodiment of the method for simulating embryo transplantation of the present invention:

[0105] A method for simulating embryo transplantation includes the following steps:

[0106] The first step is to obtain the animal's uterine data;

[0107] The second step is to calculate the ductal data of the embryo implantation structure based on the uterine data using the pre-built implantation calculation model;

[0108] The catheter data at least includes tube shape information, tube length information and tube diameter information

[0109] The third step is to calculate the brightness data required for transplantation of the developed embryo transplant structure based on the catheter data of the developed embryo transplant structure through a pre-built development calculation model;

[0110] The fourth step is to use the pre-built development simulation model based on the brightness data to obtain the size data of the reflector and complete the transplantation simulation of the development embryo.

[0111] The uterine data includes at least the insertion depth information of the developed embryo transfer structure and the position information of the cervix;

[0112] The catheter data at least includes tube shape information, tube length information and tube diameter information;

[0113] The size data of the reflector includes at least reflector distribution information, shape information, and reflective length information.

[0114] The tube shape is round tube, and the tube length is 500*A mm;

[0115] Pipe diameter information includes outer diameter and inner diameter;

[0116] The outer diameter of the tube is 1.8*A mm, and the inner diameter of the tube is 1.2*A mm;

[0117] Reflector distribution information includes ring distribution, sheet distribution, and block distribution;

[0118] The reflective length information is A mm;

[0119] 0.3≤A≤0.8.

[0120] An operational example of using the present invention to develop an embryonic transplant structure:

[0121] The steps of operating the present invention's developed embryo transfer structure are as follows:

[0122] 1. Medical staff connect the connector of the embryo transfer structure of the present invention to the syringe

[0123] 2. Align the tip of the embryo development transplantation structure of the present invention with the culture fluid in the culture dish, and pull the plunger of the syringe to aspirate a portion of the fluid;

[0124] 3. Align the tip of the embryo transfer structure of the present invention with the selected embryo in the culture dish, and pull the syringe to attract the embryo;

[0125] 4. Insert the embryo transplant structure of the present invention into the woman's uterus through the transplant tube, and push the syringe plunger under the guidance of B-ultrasound to push the embryo and liquid into the uterus so that they adhere to the uterine wall;

[0126] 5. The operation is completed and the transplant tube is removed;

[0127] 6. Check under a microscope whether there is any embryo residue in the transfer tube.

[0128] An embodiment of a device applying the method of the present invention:

[0129] A computer device comprising:

[0130] one or more processors;

[0131] a storage device for storing one or more programs;

[0132] When the one or more programs are executed by the one or more processors, the one or more processors implement the above-mentioned method for simulating embryo transfer.

[0133] A computer medium embodiment of the method of the present invention:

[0134] A computer-readable storage medium stores a computer program, which, when executed by a processor, implements the above-mentioned method for simulating the transplantation of developed embryos.

[0135] Those skilled in the art will appreciate that the embodiments of the present application may be provided as methods, systems, and computer program products. Therefore, the present application may take the form of a complete hardware embodiment, a complete software embodiment, or an embodiment combining software and hardware. Furthermore, the present application may take the form of a computer program product implemented on one or more computer-usable storage media (including but not limited to magnetic disk storage, CD-ROM, optical storage, etc.) containing computer-usable program code.

[0136] The present application is described in terms of flowcharts and / or block diagrams of the methods, devices (systems), and computer program products according to the embodiments of the present application. It should be understood that each process and / or block in the flowchart and / or block diagram and the combination of processes and / or blocks in the flowchart and / or block diagram can be implemented by computer program instructions. These computer program instructions can be provided to a processor of a general-purpose computer, a special-purpose computer, an embedded processor, or other programmable data processing device to generate a machine, so that the instructions executed by the processor of the computer or other programmable data processing device generate instructions for implementing the processes in the flowchart and / or block diagram. Figure 1a process or multiple processes and / or boxes Figure 1 A device that provides the functions specified in a block or multiple blocks.

[0137] These computer program instructions may also be stored in a computer readable memory that can direct a computer or other programmable data processing device to work in a specific manner, so that the instructions stored in the computer readable memory produce an article of manufacture comprising an instruction device, which implements the process Figure 1 a process or multiple processes and / or boxes Figure 1 The function specified in one or more boxes.

[0138] These computer program instructions can also be loaded onto a computer or other programmable data processing device so that a series of operational steps are executed on the computer or other programmable device to produce a computer-implemented process, thereby providing the instructions executed on the computer or other programmable device for implementing the process. Figure 1 a process or multiple processes and / or boxes Figure 1 A step that specifies a function in one or more boxes.

[0139] In the present application, the fixing method can be screw connection, welding, riveting, plug connection, or connection through a third component, and those skilled in the art can choose according to actual conditions.

[0140] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and not to limit it. Although the present invention has been described in detail with reference to the above embodiments, ordinary technicians in the field should understand that the specific implementation methods of the present invention can still be modified or replaced by equivalents. Any modification or equivalent replacement that does not depart from the spirit and scope of the present invention should be covered by the scope of protection of the claims of the present invention.

Claims

1. A method for simulating embryo transplantation. It is characterized by: The following steps are involved: The first step is to obtain the animal's uterine data; The second step is to calculate the ductal data of the embryo implantation structure based on the uterine data using the pre-built implantation calculation model; The catheter data at least includes tube shape information, tube length information and tube diameter information The third step is to calculate the brightness data required for transplantation of the developed embryo transplant structure based on the catheter data of the developed embryo transplant structure through a pre-built development calculation model; The fourth step is to use the pre-built development simulation model based on the brightness data to obtain the size data of the reflector and complete the transplantation simulation of the development embryo.

2. A method for simulating embryo transplantation according to claim 1, characterized in that: The uterine data includes at least the insertion depth information of the developed embryo transfer structure and the position information of the cervix; The catheter data at least includes tube shape information, tube length information and tube diameter information; The size data of the reflector includes at least reflector distribution information, shape information, and reflective length information.

3. A method for simulating embryo transplantation according to claim 2, characterized in that: The tube shape is round tube, and the tube length is 500*A mm; Pipe diameter information includes outer diameter and inner diameter; The outer diameter of the tube is 1.8*A mm, and the inner diameter of the tube is 1.2*A mm; Reflector distribution information includes ring distribution, sheet distribution, and block distribution; The reflective length information is A mm; 0.3≤A≤0.8。 4. A developing embryo transplantation structure, characterized in that: A method for simulating embryo transplantation according to any one of claims 1 to 3 is used, wherein the method comprises at least a transplantation segment capable of being placed into a human body, a reflector capable of reflecting sound waves, and a support body capable of enhancing the structural strength of the transplantation segment; The transplant section is made of soft material; The reflector is arranged on the transplant section; The support body is made of hard material; The transplanted section is partially sleeved with the support body, and the support body is spaced apart from the reflector to form a soft-hard composite developing structure in which the transplanted section is partially exposed.

5. The imaging embryo transplantation structure according to claim 4, wherein: The reflector is a developing tube (2), which is fixed to the front end of the transplanted section; The transplant section is a transplant tube (1) with a smooth outer surface.

6. The imaging embryo transplantation structure according to claim 5, characterized in that: The developing tube (2) is made of a material obtained by fusing tungsten metal powder and high polymer polyurethane, and its outer surface is smooth and burr-free. Or / and, the developing tube (2) is a through tube, the outer diameter of the tube is 0.9 mm, the inner diameter of the tube is 0.6 mm, and the length of the tube is 0.5 mm.

7. The imaging embryo transplantation structure according to claim 4, wherein: The reflective body has a smooth outer surface (2) or a ring-shaped structure or an arc-shaped structure or a sheet-shaped structure or a block-shaped structure, which is fixed to the front end or the middle position or the front position or the rear position of the transplanted segment; Alternatively, the reflector includes a plurality of block structures that can be visualized under B-ultrasound; the block structures are evenly distributed on the transplanted section.

8. The imaging embryo transplantation structure according to claim 7, wherein: The developing tube (2) is a through tube, the outer diameter of the tube is 1.8*A mm, the inner diameter of the tube is 1.2*A mm, and the length of the tube is A mm; 0.3≤A≤0.

8.

9. The imaging embryo transplantation structure according to claim 8, wherein: The support body is a support tube (3), which is made of hard stainless steel and has limit scale lines (6) on its surface; Or / and, the end of the support body away from the transplantation section is equipped with a connector (4) for connecting a syringe.

10. The imaging embryo transplantation structure according to claim 9, wherein: The connector (4) is fixed to the transplant section via a square body, and is plugged into a protective cover (7) via a truncated cone joint (5); The connecting head (4) and the transplant section are fixed together by a square body; The protective cover (7) is sleeved on the outside of the transplant section, and the length of the protective cover (7) is Y; The length of the transplanted segment is X; The length of the reflector is h; Y>(X+h); The large end of the truncated cone joint (5) is fixedly connected to the connector (4), and the small end thereof is plugged into the inner cavity of the protective cover (7), and the inner cavity of the protective cover (7) is a constant diameter structure; The truncated cone joint (5) is fixedly connected to the connecting head (4) via a truncated cone body (51).

Citation Information

Patent Citations

  • Embryo transplantation tube

    CN114246660A

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