Frangible seal pre-filled syringe

Abstract

The application discloses an easy-to-break sealed pre-filled syringe, which comprises a syringe assembly, a breakable cap, a syringe needle and a pressure applying assembly. The syringe assembly is used for containing medicine and injecting the medicine under a preset pressure. The breakable cap is connected with the injection end of the syringe assembly and is integrally injection molded with the injection end of the syringe assembly to seal the injection end of the syringe assembly. The syringe needle is used for being plugged with the injection end of the syringe assembly to inject the medicine after the breakable cap is broken. The pressure applying assembly is plugged with the pressure receiving end of the syringe assembly and is used for applying the preset pressure to the inner cavity of the syringe assembly.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medicine injection, in particular, to an easy-to-break sealing pre-filled syringe. BACKGROUND

[0002] The pre-filled syringe is to directly fill the injection medicine in the syringe, to combine the syringe and the medicine liquid package container into one, and to directly inject when used.

[0003] For example, the Chinese invention patent CN217854071U discloses a pre-filled syringe, which comprises a syringe barrel, a cap, a lock cover and a rubber plug; the cap is connected to the injection end of the syringe barrel; the lock cover is detachably connected with the cap; the rubber plug is connected with the lock cover and blocks the injection end. The pre-filled syringe has simple structure, convenient use, good sealing performance and can effectively prevent the problem of liquid leakage.

[0004] However, the injection end of the above-mentioned pre-filled syringe is sealed by extrusion fitting of the cap, the lock cover and the rubber plug, which can improve the sealing performance and prevent liquid leakage, but the extrusion fitting is easy to loosen after long-term storage, which has the risk of external gas infiltration and internal gas exhalation, thereby greatly affecting the quality of the internal medicine liquid, and is not conducive to long-term storage and large-scale industrial production. SUMMARY

[0005] The present application provides an easy-to-break sealing pre-filled syringe to solve the technical problem that the injection end of the existing pre-filled syringe adopts extrusion fitting sealing, the extrusion fitting is easy to loosen after long-term storage, the sealing performance is relatively poor, there is a risk of gas infiltration and exhalation, and the quality of the medicine liquid is difficult to guarantee.

[0006] According to one aspect of the present application, an easy-to-break sealing pre-filled syringe is provided, which comprises an injection assembly for containing medicine liquid and injecting the medicine liquid under the action of a preset pressure; an easy-to-break cap connected with the injection end of the injection assembly for integrally injection molding with the injection end of the injection assembly to seal the injection end of the injection assembly; an injection needle for plug-in fitting with the injection end of the injection assembly to inject the medicine liquid after the easy-to-break cap is broken; and a pressure applying assembly plug-in fitting connected with the pressure receiving end of the injection assembly for applying a preset pressure to the inner cavity of the injection assembly.

[0007] As a further improvement of the above technical solution:

[0008] Further, the easy-to-break cap comprises an easy-to-break part connected with the injection end of the injection assembly and a force applying part connected with the easy-to-break part, and the volume of the force applying part is greater than that of the easy-to-break part.

[0009] Further, the injection end of the injection assembly is provided with an output part arranged in a tapered shape and fixedly connected with the breakable part, and the output part is provided with an output cavity arranged in a tapered shape and used for output of the liquid medicine.

[0010] Further, the injection assembly comprises an injection barrel used for containing the liquid medicine and the medicine respectively, a separation piston arranged in the injection barrel and used for separating the inner cavity of the injection barrel into a first containing cavity and a second containing cavity and moving in the inner cavity of the injection barrel under the preset pressure applied by the pressing assembly, and a connecting groove formed by the outer protrusion of the inner wall of the injection barrel and used for containing the separation piston to connect the first containing cavity and the second containing cavity after the preset pressure is applied to the separation piston by the pressing assembly.

[0011] Further, the pressing assembly comprises a pressing piston extended into the injection barrel from the pressure receiving end of the injection barrel and sealedly combined with the inner wall of the injection barrel, and a pressing push rod connected with the pressing piston and extended to the outside of the injection barrel.

[0012] Further, the pressure receiving end of the injection barrel is provided with a pressing opening used for opening outwardly to enable the pressing piston to extend into the injection barrel, and the edge of the pressing opening is provided with a mounting edge extended outwardly in a radial direction, and the injection barrel further comprises a sealing cover sleeved on the outside of the pressing push rod and covering the mounting edge, and used for sealing the pressing opening and limiting the pressing piston and guiding the pressing push rod.

[0013] Further, the edge of the sealing cover is provided with a clamping part used for elastically clamping the edge of the mounting edge.

[0014] Further, the middle part of the sealing cover is provided with a guide hole used for the extension of the pressing push rod into the injection barrel to rotate and push the movement of the pressing piston, and the guide hole is threadedly connected with the pressing push rod.

[0015] Further, the end of the pressing push rod away from the pressing piston is provided with a pressing handle extended outwardly in a radial direction.

[0016] Further, the sealing ring is sleeved on the outside of the pressing push rod and sealedly combined with the inner wall of the injection barrel between the pressing piston and the sealing cover.

[0017] The present application has the following beneficial effects:

[0018] The pre-filled injection device with the foldable sealing cap of the present application is characterized in that the medicine to be injected is pre-filled into the injection assembly during the manufacturing process of the injection assembly, and when the injection device is used, the foldable cap is first broken by applying force, and then the injection needle is inserted, and the preset pressure is applied to the inner cavity of the injection assembly through the pressure applying assembly, so that the medicine is injected under the preset pressure, and the injection of the medicine is realized. The injection of the medicine is realized by the injection assembly, the foldable cap, the injection needle and the pressure applying assembly, and the injection end of the injection assembly is sealed by the foldable cap. Compared with the prior art, the foldable cap and the injection end of the injection assembly are integrally injection molded as a whole, which greatly improves the sealing performance, greatly reduces the risk of gas infiltration and exfiltration from the injection end of the injection assembly, ensures the quality of the medicine pre-filled in the injection assembly, can be stored for a long time, and has the advantages of simple structure, easy to break open and use, high practicability, and wide application.

[0019] In addition to the purposes, features and advantages described above, the present application has other purposes, features and advantages. The present application will be further described below with reference to the drawings. BRIEF DESCRIPTION OF DRAWINGS

[0020] The accompanying drawings, which form a part of this application, are included to provide a further understanding of the application, illustrate the preferred embodiments of the application and assist in explaining the application. In the drawings:

[0021] Figure 1 is a structure schematic view of the pre-filled injection device with the foldable sealing cap of the preferred embodiment of the present application;

[0022] Figure 2 is a structure schematic view of the pre-filled injection device with the foldable sealing cap of the preferred embodiment of the present application;

[0023] Figure 3 is a sectional view of the pre-filled injection device with the foldable sealing cap of the preferred embodiment of the present application.

[0024] LEGEND

[0025] 100, injection assembly; 110, output part; 120, injection barrel; 121, mounting edge; 122, sealing cover; 123, clamping part; 130, partition piston; 140, communication groove; 200, foldable cap; 210, foldable part; 220, force applying part; 300, pressure applying assembly; 310, pressure applying piston; 320, pressure applying push rod; 330, pressure applying handle. DETAILED DESCRIPTION

[0026] The embodiments of the present application will be described in detail below with reference to the drawings, but the present application can be implemented in various different ways as defined and covered below.

[0027] Figure 1 is a structural schematic diagram of a foldable sealed pre-filled syringe of a preferred embodiment of the present application; Figure 2 is a structural schematic diagram of a foldable sealed pre-filled syringe of a preferred embodiment of the present application; Figure 3 is a sectional view of a foldable sealed pre-filled syringe of a preferred embodiment of the present application.

[0028] As shown in Figure 1 , the foldable sealed pre-filled syringe of the present embodiment comprises a syringe assembly 100 for containing and injecting a drug liquid under a preset pressure; a foldable cap 200 connected with the injection end of the syringe assembly 100 for integrally injection molding with the injection end of the syringe assembly 100 to seal the injection end of the syringe assembly 100; a syringe needle for plugging and cooperating with the injection end of the syringe assembly 100 after the foldable cap 200 is broken to inject the drug liquid; and a pressure applying assembly 300 plugging and cooperating with the pressure receiving end of the syringe assembly 100 for applying a preset pressure to the inner cavity of the syringe assembly 100. Specifically, the foldable sealed pre-filled syringe of the present application, the drug liquid to be injected is pre-filled into the syringe assembly 100 during the manufacturing process of the syringe assembly 100, and when the syringe is used, the foldable cap 200 is first broken by applying force, then the syringe needle is inserted, and a preset pressure is applied to the inner cavity of the syringe assembly 100 by the pressure applying assembly 300 to inject the drug liquid under the preset pressure, thereby realizing the injection of the drug liquid. The present scheme realizes the injection of the drug liquid by the syringe assembly 100, the foldable cap 200, the syringe needle and the pressure applying assembly 300, and the foldable cap 200 is used to seal the injection end of the syringe assembly 100. Compared with the prior art, the foldable cap 200 and the injection end of the syringe assembly 100 are integrally injection molded as a whole, which greatly improves the sealing performance, greatly reduces the risk of gas infiltration and exfiltration from the injection end of the syringe assembly 100, ensures the quality of the pre-filled drug liquid in the syringe assembly 100, and can be stored for a long time. The structure is simple, conducive to large-scale industrial production, the foldable cap 200 is easy to break and open, and has strong practicality and is suitable for wide promotion and application.

[0029] As shown in Figure 1 , in the present embodiment, the foldable cap 200 comprises a foldable part 210 connected with the injection end of the syringe assembly 100 and a force applying part 220 connected with the foldable part 210, and the volume of the force applying part 220 is greater than that of the foldable part 210. Specifically, the volume of the force applying part 220 is greater than that of the foldable part 210, so that the pressure receiving area of the force applying part 220 is relatively large, facilitating force application, while the strength of the foldable part 210 is relatively low, facilitating breaking, thereby facilitating the application of force to the force applying part 220 to break the foldable part 210, thereby opening the injection end of the syringe assembly 100 to insert the syringe needle to inject the drug liquid.

[0030] As Figure 3 shown in the embodiment, the injection end of the injection assembly 100 is provided with an output portion 110 arranged in a tapered manner and fixedly connected with the breakable portion 210, and the output portion 110 is provided with an output cavity arranged in a tapered manner for output of the liquid medicine. Specifically, the output cavity arranged in a tapered manner is formed by the output portion 110 arranged in a tapered manner, so that the liquid medicine is gathered into the output cavity, and after the breakable portion 210 is broken, the output cavity and the injection needle are inserted and connected, the injection of the liquid medicine is realized, and the residual liquid medicine is avoided.

[0031] As Figure 3 shown in the embodiment, the injection assembly 100 includes an injection barrel 120 for containing the liquid medicine and the medicine, respectively, a separation piston 130 arranged in the injection barrel 120 and used for separating the inner cavity of the injection barrel 120 into a first containing cavity and a second containing cavity and moving in the inner cavity of the injection barrel 120 under the action of a preset pressure applied by a pressure applying assembly 300, and a communication groove 140 formed by the inner wall of the injection barrel 120 and outwardly protruding and used for containing the separation piston 130 to communicate the first containing cavity and the second containing cavity after the pressure applying assembly 300 applies the preset pressure to the separation piston 130. Specifically, the first containing cavity contains the liquid medicine, and the second containing cavity contains the medicine, so that after the pressure applying assembly 300 pushes the liquid medicine to apply the preset pressure to the separation piston 130, the separation piston 130 moves in the inner cavity of the injection barrel 120, the communication cavity contains the separation piston 130 and communicates the first containing cavity and the second containing cavity, the mixing of the two medicines is performed, the medicine dispensing in a fully sealed environment is realized, the pollution caused by the medicine dispensing is avoided, and the medicine can be a soluble solid medicine. The soluble solid medicine is mixed with the liquid medicine to be dissolved in the liquid medicine and then injected into the patient's body, so that the selection range of the medicine is greatly improved. Alternatively, in another embodiment, the first containing cavity contains the medicine, and the second containing cavity contains the liquid medicine. Alternatively, the output cavity and the second containing cavity are communicated. Alternatively, the output cavity and the first containing cavity are communicated. Alternatively, a limiting protrusion corresponding to the communication groove 140 is protruded on the inner wall of the injection barrel 120, so that the limiting protrusion can be passed only when the pressure applying assembly 300 further increases the preset pressure, so as to ensure that the medicines in the first containing cavity and the second containing cavity are fully mixed.

[0032] As Figure 3 shown in the embodiment, the pressure applying assembly 300 includes a pressure applying piston 310 extending into the injection barrel 120 from the pressure receiving end of the injection barrel 120 and sealingly abutting the inner wall of the injection barrel 120, and a pressure applying push rod 320 connected with the pressure applying piston 310 and extending out of the injection barrel 120. Specifically, by applying a force to the pressure applying push rod 320, the pressure applying piston 310 is driven to move in the injection barrel 120, the preset pressure is applied to the separation piston 130, and the injection of the liquid medicine is realized.

[0033] As shown in Figure 3 In this embodiment, the pressure receiving end of the syringe 120 is provided with a pressure applying port for opening outwardly to allow the pressure applying piston 310 to extend into the syringe 120, the edge of the pressure applying port is provided with a mounting edge 121 formed by extending radially outwardly, and the syringe 120 further comprises a sealing cover 122 sleeved on the pressure applying push rod 320 and covering the mounting edge 121, which is used for sealing the pressure applying port and limiting the pressure applying piston 310 and guiding the pressure applying push rod 320. Specifically, the pressure applying piston extends into the syringe 120 from the pressure applying port of the syringe 120, and then the sealing cover 122 is mounted through the mounting edge 121 to increase the area of the surface-to-surface sealing, reliably seal the pressure applying port, prevent the drug solution from leaking, limit the pressure applying piston 310 from being pulled out of the syringe 120, and guide the movement direction of the pressure applying push rod 320 to ensure the reliable movement direction of the pressure applying push rod 320.

[0034] As shown in Figure 3 In this embodiment, the edge of the sealing cover 122 is provided with a clamping portion 123 for elastically clamping the mounting edge 121, which wraps the edge of the mounting edge 121. Specifically, the edge of the mounting edge 121 is wrapped by the clamping portion 123 to elastically clamp the mounting edge 121, which facilitates the disassembly and assembly of the sealing cover 122 and improves the assembly efficiency.

[0035] As shown in Figure 3 In this embodiment, a guide hole is formed in the middle of the sealing cover 122, which is used for the pressure applying push rod 320 to extend into the syringe 120 to rotate and push the pressure applying piston 310 to move, and the guide hole is threadedly connected with the pressure applying push rod 320. Specifically, the guide hole is threadedly connected with the pressure applying push rod 320 to realize the extension and retraction of the pressure applying push rod 320 by rotating the pressure applying push rod 320, thereby facilitating the control of the extension amount of the pressure applying push rod 320 and realizing the accurate injection of the drug solution.

[0036] As shown in Figure 3 In this embodiment, the end of the pressure applying push rod 320 away from the pressure applying piston 310 is provided with a pressure applying handle 330 formed by extending radially outwardly. Specifically, the pressure applying handle 330 facilitates the user to apply a torque to the pressure applying push rod 320 to drive the pressure applying push rod 320 to rotate.

[0037] In this embodiment, a sealing ring is provided between the pressure applying piston 310 and the sealing cover 122, which is sleeved on the pressure applying push rod 320 and sealingly abuts against the inner wall of the syringe 120. Specifically, the sealing ring improves the sealing performance of the pressure receiving end of the syringe 120 to prevent the drug solution from leaking and facilitates the long-term storage of the drug in the syringe 120.

[0038] The above merely provides the preferred embodiments of the present application, and is not used to limit the present application. For those skilled in the art, the present application can have various modifications and changes. Any modifications, equivalent replacements, improvements, etc. made within the principles and technical scope of the present application shall fall into the scope of the present application.

Claims

1. A frangible sealed pre-filled syringe, characterized in that, The injection device comprises an injection assembly (100) for containing a medicine and injecting the medicine under a preset pressure; A breakable cap (200) is connected with the injection end of the injection assembly (100) and integrally injection molded with the injection end of the injection assembly (100) to seal the injection end of the injection assembly (100); An injection needle is inserted into the injection end of the injection assembly (100) after the breakable cap (200) is broken to inject the medicine; A pressure applying assembly (300) is connected with the pressure receiving end of the injection assembly (100) to apply a preset pressure to the inner cavity of the injection assembly (100); The injection device further comprises a breakage preventing cap sleeved on the breakable cap (200) and connected with the injection assembly (100). The injection assembly (100) comprises an injection barrel (120) for containing the medicine and the medicine, a partition piston (130) arranged in the injection barrel (120) to divide the inner cavity of the injection barrel (120) into a first containing cavity and a second containing cavity and to move in the inner cavity of the injection barrel (120) under the preset pressure applied by the injection assembly (100), and a communication groove (140) formed by the outer projection of the inner wall of the injection barrel (120) to contain the partition piston (130) to communicate the first containing cavity and the second containing cavity after the preset pressure is applied to the partition piston (130) by the pressure applying assembly (300). The inner wall of the injection barrel (120) is provided with a limiting protrusion corresponding to the communication groove (140), and the pressure applying assembly (300) can pass through the limiting protrusion only when the preset pressure is applied, so as to ensure that the medicine in the first containing cavity and the second containing cavity is fully mixed. The breakable cap (200) comprises a breakable part (210) connected with the injection end of the injection assembly (100) and a force applying part (220) connected with the breakable part (210), and the volume of the force applying part (220) is greater than that of the breakable part (210).

2. The frangible sealed pre-filled syringe of claim 1, wherein, The injection end of the injection assembly (100) is provided with an output part (110) arranged in a tapered shape and fixedly connected with the breakable part (210), and the output part (110) is provided with an output cavity arranged in a tapered shape and used for outputting the medicine.

3. The frangible sealed pre-filled syringe of claim 2, wherein, The pressure applying assembly (300) comprises a pressure applying piston (310) extending into the injection barrel (120) from the pressure receiving end of the injection barrel (120) and sealingly abutting against the inner wall of the injection barrel (120), and a pressure applying push rod (320) connected with the pressure applying piston (310) and extending out of the injection barrel (120).

4. The frangible sealed pre-filled syringe of any of claims 1-3, wherein, The pressure receiving end of the injection barrel (120) is provided with a pressure applying opening opened outwardly to allow the pressure applying piston (310) to extend into the injection barrel (120), and the edge of the pressure applying opening is provided with a mounting edge (121) extending radially outwardly, and the injection barrel (120) further comprises a sealing cover (122) sleeved on the pressure applying push rod (320) and covering the mounting edge (121) to seal the pressure applying opening and limit the pressure applying piston (310) and guide the pressure applying push rod (320).

5. The frangible sealed pre-filled syringe of claim 4, wherein, The edge of the sealing cover (122) is provided with a clamping part (123) wrapping the edge of the mounting edge (121) to elastically clamp the mounting edge (121).

6. The frangible sealed pre-filled syringe of claim 5, wherein, ​ 7. The frangible sealed pre-filled syringe of claim 5, wherein, A middle portion of the sealing cover (122) is provided with a guide hole in threaded connection with the pressing push rod (320) for the pressing push rod (320) to extend into the injection cylinder (120) to rotate and push the pressing piston (310) to move.

8. The frangible sealed pre-filled syringe of claim 7, wherein, An end of the pressing push rod (320) away from the pressing piston (310) is provided with a pressing handle (330) extending radially outward.

9. The frangible sealed pre-filled syringe of claim 5, wherein, A sealing ring is arranged between the pressing piston (310) and the sealing cover (122), and is sleeved on the pressing push rod (320) and is in sealing abutment with the inner wall of the injection cylinder (120).

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