A composition containing a pyrethroid insecticide and its application

Abstract

The present invention relates to a composition containing a biologically effective amount of Compound I and a pyrethroid insecticide, and methods for using them to control pests in agricultural and non-agricultural environments. Compound I has a synergistic effect with the pyrethroid insecticide, which can improve the pest control effect, reduce the dosage of pesticides, reduce the number of applications, and lower the use cost.

Description

Technical Field

[0001] The present invention belongs to the technical field of pesticide compounding, and specifically relates to a composition containing a biologically effective amount of Compound I and at least one pyrethroid insecticide, and methods for using them to control pests in agricultural and non-agricultural environments. Background Art

[0002] In recent years, the occurrence of various crop pests has shown an increasing trend year by year, and the occurrence area has been increasing year by year, causing great harm to crops, resulting in problems such as crop yield reduction and increased agricultural production costs. In order to improve the control effect on pests, farmers increase the dosage of pesticides or mix pesticides randomly. This unscientific use of pesticides not only fails to achieve a synergistic effect, but also leads to problems such as pesticide waste, excessive residues, environmental pollution, and the development of pest resistance to pesticides. Therefore, there is an urgent need to develop a composition for pests that can achieve the effects of expanding the scope of controlled pests, reducing the dosage of pesticides, and delaying the development of resistance.

[0003] In the actual process of agricultural production, if the same pesticide is used continuously and singly for a long time, pests will quickly develop resistance, resulting in a reduced control effect, an increase in the amount of pesticide used, and an exacerbation of pesticide residues in agricultural products and damage to the ecological environment. Compounding with insecticide varieties with completely different action mechanisms is an effective way to delay the development of pest resistance, expand the insecticidal spectrum, extend the service life, and reduce the amount of pesticide used. However, how to compound them so that there is a synergistic rather than antagonistic effect between the drugs is a major difficulty.

[0004] Patent document CN 111909143 A discloses Compound I, which has broad-spectrum insecticidal activity and has good control effects especially on pests such as Lepidoptera, Hemiptera, Coleoptera, Thysanoptera, Diptera, and mites. However, it does not disclose how to compound it with other drugs to achieve a synergistic purpose.

[0005] The structural formula of Compound I is shown as follows,

[0006]

[0007] Pyrethroids are a class of insecticides that are artificially synthesized and mimic the chemical structure of natural pyrethrins. They are sodium channel regulators and their insecticidal effects are mainly contact and stomach poisons. Pyrethroids have the following advantages: (1) High efficiency: The insecticidal activity is 2 to 10 times that of general organophosphorus insecticides; (2) Broad spectrum: They have good control effects on a variety of fruit tree pests, such as apple and pear borers, cutworms, stink bugs, flat boat moths, geometrids, and pests with chewing and piercing-sucking mouthparts; (3) Low toxicity: The toxicity to humans and animals is lower than that of organophosphorus and carbamate pesticides, and the dosage is small and safe to use; (4) Low residue: The pollution to crops and the environment is relatively light, and they are easy to decompose in the natural environment, with low residue. At present, there are nearly 80 pyrethroid insecticides developed worldwide, of which 24 are used for agricultural pest control.

[0008] However, the above two compounds still have the problem of drug resistance and insecticidal activity needs to be improved. Summary of the invention

[0009] In order to improve the deficiencies of the prior art, the present invention provides a composition comprising compound I and a pyrethroid insecticide, wherein the pyrethroid insecticide is selected from at least one of the following: cypermethrin, high-efficiency cypermethrin, cyhalothrin, high-efficiency cyhalothrin, cyfluthrin, high-efficiency cyhalothrin, cypermethrin, cyfluthrin, etofenprox, tefluthrin, deltamethrin, cypromethrin and bifenthrin;

[0010] The structural formula of compound I is shown below:

[0011]

[0012] According to an embodiment of the present invention, the compound I is prepared by referring to the method of Example 1 in patent document CN 111909143 A, the entire text of which is incorporated herein by reference.

[0013] According to an embodiment of the present invention, the mass ratio of the compound I to the pyrethroid insecticide is 80-1:1-80.

[0014] According to an embodiment of the present invention, the mass ratio of compound I to pyrethroid insecticide is 50-1:1-50, for example, 50:1, 10:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:10 or 1:50.

[0015] According to a preferred embodiment of the present invention, the mass ratio of the compound I to the pyrethroid insecticide is 10-1:1-10.

[0016] According to an embodiment of the present invention, based on the total weight of the composition being 100%, the sum of the masses of Compound I and the pyrethroid insecticide in the composition is 1% to 80%, preferably 1%, 10%, 15%, 20%, 25%, 30%, 50%.

[0017] According to an embodiment of the present invention, the composition can be prepared into a liquid preparation or a solid preparation.

[0018] According to an embodiment of the present invention, according to different preparation types, the content range of the effective active ingredient in the preparation is different. Generally, the liquid preparation contains 1% to 60% of the effective active ingredient by weight, preferably 5% to 50%; the solid preparation contains 5% to 80% of the effective active ingredient by weight, preferably 10% to 70%.

[0019] According to an embodiment of the present invention, the composition further includes at least one of deionized water, organic solvents, emulsifiers, dispersants, wetting agents, thickeners, defoamers, stabilizers, binders, disintegrants, antifreeze agents, anticaking agents, suspending agents, film-forming agents, preservatives, colorants, polymer wall materials, pH regulators, or fillers, etc.

[0020] According to an embodiment of the present invention, the composition can be diluted by the user before use or used directly. Its preparation can be prepared by processing methods well-known to those skilled in the art, that is, mixing the effective active ingredient with one or several of deionized water, organic solvents, emulsifiers, dispersants, wetting agents, thickeners, defoamers, stabilizers, binders, disintegrants, antifreeze agents, anticaking agents, suspending agents, film-forming agents, preservatives, colorants, polymer wall materials, pH regulators, or fillers, etc., to obtain the composition.

[0021] According to an embodiment of the present invention, the composition can be made into various dosage forms. Preferably, the dosage forms include wettable powders, water dispersible granules, suspensions, emulsifiable concentrates, suspension seed coating agents, microcapsule suspensions, microcapsule suspension-suspensions, emulsifiable oils, microemulsions, dispersible liquid agents, granules.

[0022] According to an embodiment of the present invention, when the composition is made into a wettable powder, it contains the following components and contents: Compound I 1% to 80%, pyrethroid insecticide 1% to 80%, dispersant 0% to 10%, wetting agent 0% to 8%, and the balance is filler.

[0023] According to an embodiment of the present invention, when the composition is made into water dispersible granules, it includes the following components and contents: Compound I 1% to 80%, pyrethroid insecticide 1% to 80%, dispersant 0% to 10%, wetting agent 0% to 16%, disintegrant 0% to 20%, and the balance is filler.

[0024] According to an embodiment of the present invention, when the composition is made into a suspending agent, it includes the following components and contents: Compound I 1% - 50%, pyrethroid insecticide 1% - 50%, dispersant 0% - 5%, wetting agent 0% - 8%, thickener 0% - 0.3%, antifreezing agent 0% - 5%, and the balance is deionized water.

[0025] According to an embodiment of the present invention, when the composition is made into an emulsion in water, it includes the following components and contents: Compound I 1% - 50%, pyrethroid insecticide 1% - 50%, organic solvent 0% - 95%, emulsifier 0% - 10%, antifreezing agent 0% - 5%, defoaming agent 0% - 0.2%, thickener 0% - 0.5%, and the balance is deionized water.

[0026] According to an embodiment of the present invention, when the composition is made into a suspension seed coating agent, it includes the following components and contents: Compound I 1% - 50%, pyrethroid insecticide 1% - 50%, dispersant 1% - 12%, wetting agent 1% - 10%, antifreezing agent 1 - 10%, anticaking agent 0.1 - 10%, suspending aid 0.1 - 5%, film-forming agent 1 - 10%, preservative 0.1 - 5%, colorant 1 - 30%, pH regulator 0.1% - 5%, thickener 0.1% - 8%, and the balance is deionized water.

[0027] According to an embodiment of the present invention, when the composition is made into a microcapsule suspension, it includes the following components and contents: Compound I 1% - 50%, pyrethroid insecticide 1% - 50%, high molecular capsule wall material 1 - 30%, dispersant 2% - 10%, organic solvent 1 - 50%, emulsifier 1% - 7%, pH regulator 0.1% - 5%, defoaming agent 0.01% - 2%, thickener 0.1% - 8%, antifreezing agent 0.1% - 8%, and the balance is deionized water.

[0028] According to an embodiment of the present invention, when the composition is made into a microcapsule suspension-suspending agent, it includes the following components and contents: Compound I 1% - 50%, pyrethroid insecticide 1% - 50%, high molecular capsule wall material 1% - 12%, dispersant 1% - 12%, wetting agent 1% - 8%, organic solvent 1 - 50%, emulsifier 1% - 8%, defoaming agent 0.01% - 2%, thickener 0.1% - 8%, pH regulator 0.1% - 5%, antifreezing agent 0.1% - 8%, and the balance is deionized water.

[0029] According to an embodiment of the present invention, when the composition is made into an emulsifiable concentrate, it includes the following components and contents: Compound I 1% - 50%, pyrethroid insecticide 1% - 50%, emulsifier 0 - 10%, antifreezing agent 0% - 5%, stabilizer 0% - 0.5%, and the balance is organic solvent;

[0030] Alternatively, the composition comprises 1% - 50% of Compound I, 1% - 50% of pyrethroid insecticide, 0 - 12% of emulsifier, 0% - 0.5% of stabilizer, and the balance is organic solvent.

[0031] According to an embodiment of the present invention, when the composition is made into a microemulsion, it comprises the following components and contents: 1% - 50% of Compound I, 1% - 50% of pyrethroid insecticide, 1 - 50% of organic solvent, 1 - 30% of emulsifier, 1% - 10% of antifreeze agent, 0.1% - 5% of stabilizer, and the balance is deionized water.

[0032] According to an embodiment of the present invention, when the composition is made into a dispersible concentrate, it comprises the following components and contents: 1% - 50% of Compound I, 1% - 50% of pyrethroid insecticide, 1 - 30% of emulsifier, 1% - 10% of antifreeze agent, 0.1% - 5% of stabilizer, and the balance is organic solvent.

[0033] According to an embodiment of the present invention, when the composition is made into a granule, it comprises the following components and contents: 0.1% - 10% of Compound I, 0.1% - 10% of pyrethroid insecticide, 0% - 5% of dispersant, 0% - 5% of wetting agent, 0% - 3% of binder, and the balance is filler.

[0034] According to an embodiment of the present invention, the emulsifier can be selected from at least one of the following: sodium lignosulfonate, agricultural emulsifier, phenylphenol polyoxyethyl ether phosphate ester, triethanolamine salt of triphenylvinylphenol polyoxyethylene ether phosphate ester, benzyl dimethylphenol polyoxyethyl ether, polyoxyethylene sorbitan fatty acid ester, sorbitan oleate (Span - 80), fatty alcohol polyoxyethylene ether, alkylnaphthalenesulfonate, sodium isooctyl sulfosuccinate, nonylphenol polyoxyethylene ether phosphate ester, castor oil polyoxyethylene ether phosphate ester.

[0035] According to an embodiment of the present invention, the dispersant can be selected from at least one of the following: polyoxyethylene glycerol fatty acid ether, polyoxyethylene alkylaryl ether, sodium lignosulfonate, naphthalene sulfonate formaldehyde condensate, fatty alcohol polyoxyethylene ether sulfate, naphthalene sulfonate formaldehyde condensate, sodium salt of naphthalene sulfonate formaldehyde condensate, nonylphenol polyoxyethylene ether, polyoxyethylene lanolin alcohol, alkylphenol polyoxyethylene ether formaldehyde condensate, fatty alcohol polyoxyethylene ether, fatty alcohol polyoxyethylene ether phosphate ester, polyoxyethylene sorbitan fatty acid ester, phosphate ester.

[0036] According to an embodiment of the present invention, the wetting agent can be selected from at least one of: trisiloxane polyoxyethylene ether, sodium N-lauroyl glutamate, sodium dodecyl sulfate, sodium lauroyl sarcosinate, formaldehyde condensate of methylnaphthalenesulfonic acid, castor oil polyoxyethylene ether, triphenylethylphenol polyoxyethylene ether, sodium dodecylbenzenesulfonate, alkylnaphthalenesulfonate, sodium isooctyl sulfosuccinate, polyoxyethylene alkylaryl ether, fatty alcohol polyether glycerol fatty acid polyoxyethylene ether, and fatty alcohol polyoxyethylene ether.

[0037] According to an embodiment of the present invention, the binder can be selected from at least one of: xanthan gum, starch, urea-formaldehyde resin, gelatin, gum arabic, carboxymethyl cellulose, carboxyethyl cellulose, and polyvinyl alcohol.

[0038] According to an embodiment of the present invention, the disintegrant can be selected from at least one of: sodium bicarbonate, ammonium sulfate, sodium sulfate, calcium sulfate, and magnesium chloride.

[0039] According to an embodiment of the present invention, the thickener can be selected from at least one of: magnesium aluminum silicate, polyvinyl acetate, xanthan gum, gelatin, gum arabic, and polyvinyl alcohol.

[0040] According to an embodiment of the present invention, the defoamer can be selected from at least one of: silicone oil, n-octanol, silicone, tributyl phosphate, isobutyl phosphate, etc.

[0041] According to an embodiment of the present invention, the antifreeze can be selected from at least one of: propylene glycol, ethylene glycol, glycerol, etc.

[0042] According to an embodiment of the present invention, the stabilizer can be selected from at least one of: triethanolamine, epichlorohydrin, butyl glycidyl ether, triphenyl phosphite, N-soybean oil-based trimethylenediamine, dialkyl sulfosuccinate, etc.

[0043] According to an embodiment of the present invention, the filler includes solid filler and liquid filler. Among them, the solid filler can be selected from at least one of: kaolin, attapulgite, diatomite, silica, bentonite, montmorillonite, calcium carbonate, and talc powder. The liquid filler can be selected from at least one of: soybean oil, castor oil, and mineral oil.

[0044] According to an embodiment of the present invention, the organic solvent can be selected from at least one of: ethyl acetate, acetone, isopropanol, 2,2,2-trifluoroethanol, propylene carbonate, benzene, toluene, xylene, dimethylformamide, dimethyl sulfoxide, dichloromethane, cyclohexane, cyclohexanone, N-methylpyrrolidone, solvent oil (such as 150# solvent oil).

[0045] The present invention also provides the use of the above composition for controlling pests in agriculture and non-agriculture.

[0046] According to an embodiment of the present invention, the pests are pests such as Lepidoptera, Hemiptera, Coleoptera, Thysanoptera, Diptera, mites, etc.

[0047] As an embodiment, the pests are selected from the following: Mythimna separata, Plutella xylostella, Spodoptera exigua, Diaphania indica, Aphis gossypii, Sitobion avenae, Bemisia tabaci, and Empoasca vitis.

[0048] The present invention also provides a method for controlling agricultural or non-agricultural pests, which includes applying the above composition to plants with pests.

[0049] The composition of the present invention can be provided in the form of a finished preparation or in the form of single agents, directly mixed before use, and then diluted with water and mixed evenly to prepare the required concentration, and can be applied to crops in any way, such as spraying, irrigation at the roots of plants, smearing, etc. When specifically applied, it can also be mixed and used with other agents such as growth regulators, soil conditioners, herbicides, nematicides, etc.

[0050] The present invention also provides a composition for controlling invertebrate pests, which contains a biologically effective amount of Compound I, pyrethroid insecticides and at least one other component selected from surfactants, solid diluents, and liquid diluents. The composition optionally further contains an effective amount of at least one other biologically active compound or active agent. The pyrethroid insecticides are selected from at least one of the following: cypermethrin, beta-cypermethrin, cyhalothrin, lambda-cyhalothrin, flucythrinate, beta-flucythrinate, etofenprox, heptafluthrin, deltamethrin, fenpropathrin, and bifenthrin.

[0051] The present invention also provides a method for controlling invertebrate pests, which includes bringing the invertebrate pests or their environment into contact with a biologically effective amount of the composition of the present invention as described above.

[0052] The present invention also provides a spray composition, which contains the composition of the present invention as described above and a propellant.

[0053] The present invention also provides a bait composition, which contains the composition of the present invention as described above; one or more food materials; an optional attractant; and an optional wetting agent.

[0054] Advantages of the present invention:

[0055] The composition of the present invention has the following advantages:

[0056] 1) It has a synergistic effect and can improve the pest control effect; 2) It expands the insecticidal spectrum. Since multiple pests often occur mixed in the field, it has a stronger effect on pests; 3) The two active ingredients have different action mechanisms, and their mixed use can delay the emergence of pest resistance; 4) It reduces the dosage of pesticides, the number of applications, and the use cost. Detailed implementation mode

[0057] The following will further elaborate on the present invention in combination with specific embodiments. It should be understood that the following embodiments are only for illustrative and explanatory purposes of the present invention and should not be construed as limiting the protection scope of the present invention. All technologies implemented based on the above content of the present invention are covered within the scope of protection intended by the present invention.

[0058] Unless otherwise specified, the experimental methods used in the following examples are all conventional methods; the reagents, materials, etc. used in the following examples can all be obtained from commercial channels unless otherwise specified.

[0059] The present invention uses a method combining indoor bioassay and field trials to test the insecticidal effect of the composition. It should be noted that any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included within the protection scope of the present invention.

[0060] Compound I used in the following examples was prepared by referring to the method in Example 1 of Patent Document CN 111909143 A.

[0061] Unless otherwise specified, the % in each component of the formulations in the following examples refers to mass percentage.

[0062] I. Formulation preparation examples:

[0063] Preparation Example 1: Wettable powder

[0064]

[0065]

[0066] The above materials are coarsely pulverized according to the ratio and then mixed evenly in a mixer, and then obtained as a finished product after air flow pulverization.

[0067] Preparation Example 2: Water dispersible granule

[0068]

[0069] The active ingredients and various auxiliaries are mixed evenly according to the formula ratio, and after air flow pulverization, a powder material is obtained. Then, a certain amount of water is added and mixed and extruded into granules, and the finished product is obtained after drying and screening.

[0070] Preparation Example 3: Suspension concentrate

[0071]

[0072] Mix the active ingredient and various additives evenly according to the formula ratio, and obtain the finished product after high-speed shearing and sand grinding.

[0073] Preparation Example 4: Emulsifiable Concentrate

[0074]

[0075]

[0076] Mix the above raw materials in proportion to dissolve them into a uniform oil phase; after passing the inspection, conduct metering and packaging to obtain the finished product.

[0077] Preparation Example 5: Emulsion in Water

[0078]

[0079] According to the formula requirements, add the above raw materials to the batching kettle, mix them evenly by a high-speed shearing machine to prepare an emulsion in water, and after passing the inspection, conduct metering and packaging to obtain the finished product.

[0080] Preparation Example 6: Emulsifiable Concentrate

[0081]

[0082] Mix the above raw materials in proportion to dissolve them into a uniform oil phase; after passing the inspection, conduct metering and packaging to obtain the finished product.

[0083] Preparation Example 7: Granules

[0084]

[0085]

[0086] Mix each component fully according to the formula ratio, crush it, moisten it with water and then stir evenly, and then granulate it with a screw extrusion granulator, and sieve it after drying to obtain the finished product.

[0087] In the above preparation examples, the pyrethroid agents are selected from one of cypermethrin, beta-cypermethrin, cyhalothrin, lambda-cyhalothrin, flucythrinate, beta - flucythrinate, ethofenprox, heptafluthrin, deltamethrin, fenpropathrin and bifenthrin.

[0088] II. Indoor Toxicity Determination Examples

[0089] (1) Test pests: cotton aphids (Aphis gossypii Glover), tomato whiteflies (Bemisia tabaci), diamondback moths on cabbage (Plutella xylostella), and oriental armyworms on corn (Mythimna separata Walker).

[0090] (2) Determination method:

[0091] Pest toxicity determination method

[0092] For the pest toxicity determination, cotton aphids were used as the test materials, and the dipping method was adopted to determine the toxicity of Compound I, pyrethroid insecticides, and their mixed preparations.

[0093] Referring to the Agricultural Industry Standard of the People's Republic of China NY / T 1154.6 - 2006 "Pesticide Bioassay Test Guidelines in the Laboratory" Part 6: Insecticidal Activity Test - Dipping Method, first, the test agents (including Compound I and pyrethroid insecticides) were formulated into 5 concentration gradients with a suitable solvent (solvent types such as acetone, methanol, N, N - dimethylformamide, and dimethyl sulfoxide, etc., and selected according to their solubility in the sample). The concentration gradients were set according to the LC 50 value of the compound against different pests, either geometrically or arithmetically. For the compound I and pyrethroid insecticides to be mixed, a series of ratios were set according to their LC 50 values by mass ratio, and they were formulated into the final mass concentration (total mass of Compound I and pyrethroid insecticides) according to different ratios.

[0094] After the target insects were immersed in the liquid medicine for 5 s - 10 s, the excess liquid medicine was blotted with filter paper, and the test insects were transferred to be reared under normal conditions. Each treatment had 4 replicates, with 10 - 20 insects dipped in each replicate, and a treatment with the corresponding organic solvent without the agent was set as the control.

[0095] For the pest toxicity determination, diamondback moths on cabbage, oriental armyworms on corn, tomato whiteflies, etc. were used as the test materials, and the leaf - dipping method was adopted to determine the toxicity of Compound I, pyrethroid insecticides, and their mixed preparations.

[0096] Referring to the Agricultural Industry Standard of the People's Republic of China NY / T 1154.14 - 2008 "Pesticide Bioassay Test Guidelines in the Laboratory" Part 14: Leaf - Dipping Method, first, the test agents (including Compound I and pyrethroid insecticides) were formulated into 5 concentration gradients with a suitable solvent (solvent types such as acetone, methanol, N, N - dimethylformamide, and dimethyl sulfoxide, etc., and selected according to their solubility in the sample). The concentration gradients were set according to the LC 50values, set the concentration gradient according to a geometric or arithmetic progression), and compound I and pyrethroid insecticides to be mixed are respectively according to their LC 50 values, set a series of ratios according to the mass ratio, and prepare the final mass concentration (referring to the total mass of compound I and pyrethroid insecticides) according to different ratios.

[0097] Immerse the leaf discs or leaf segments in the test agent solution, take them out and dry them after 10 s (the dipping time can be appropriately extended or shortened according to the characteristics of the agent), place them in a petri dish containing 1% water agar or moist filter paper, and inoculate the test insects, with no less than 10 insects per repetition. Each treatment has no less than 4 repetitions, and a treatment without the agent (including all organic solvents and emulsifiers) is set as a blank control.

[0098] Calculate the co-toxicity coefficient (CTC value) of the two agents with different ratios according to the Sun Yunpei method. A co-toxicity coefficient (CTC) of the compound agent ≥ 120 indicates a synergistic effect, CTC ≤ 80 indicates an antagonistic effect; 80 < CTC < 120 indicates an additive effect. The co-toxicity coefficient (CTC) of the mixture is calculated according to formulas (1), (2), and (3):

[0099]

[0100] In the formula:

[0101] ATI—the measured toxicity index of the mixture;

[0102] S—the LC 50 , in milligrams per liter (mg / L);

[0103] M—the LC 50 , in milligrams per liter (mg / L)

[0104] TTI = TI A ×P A +TI B ×P B (2)

[0105] In the formula:

[0106] TTI—the theoretical co-toxicity index of the mixture;

[0107] TI A —the toxicity index of agent A;

[0108] P A —the percentage content of agent A in the mixture, in percentage (%);

[0109] TI B —the toxicity index of agent B;

[0110] P B——Percentage content of Agent B in the mixture, in percentage (%)

[0111]

[0112] Wherein:

[0113] CTC - Co-toxicity coefficient

[0114] ATI - Actual toxicity index of the mixture

[0115] TTI - Theoretical toxicity index of the mixture

[0116] After mixing different varieties of pesticides, three types of action are usually exhibited, namely additive action, synergistic action and antagonistic action. However, it is impossible to predict which specific action it is. The composition described in the present invention uses Compound I and pyrethroid insecticides as active ingredients, and is illustrated by bioassay examples.

[0117] Indoor determination test of the activity of pesticides against Plutella xylostella on cabbage

[0118] In this test, the leaf dipping method was used to conduct an indoor activity determination test of the compound against Plutella xylostella on cabbage, in order to determine the activity of the insecticidal compositions of Examples 1 - 4 against Plutella xylostella on cabbage.

[0119] Example 1: To verify the effects of different ratios and dosages of Compound I and cypermethrin on Plutella xylostella on cabbage, an indoor toxicity determination of different ratios of Compound I and cypermethrin against Plutella xylostella on cabbage was carried out. Corresponding concentrations were prepared according to the mass ratios in the table, and an indoor insecticidal test was conducted. The test results are as follows:

[0120] Table 1 Results of toxicity determination of Compound I, cypermethrin and their mixtures against Plutella xylostella on cabbage

[0121] Active ingredient Ratio Regression equation <![CDATA[LC 50 > Coefficient of co-toxicity Evaluation Compound I — y = 6.8787 + 2.1062x 0.1282 — — Cypermethrin — y = 2.0431 + 1.8300x 41.2851 — — Compound I: Cypermethrin 50：1 y = 6.8856 + 1.9250x 0.1048 124.77 Synergistic Compound I: Cypermethrin 10：1 y = 7.0488 + 1.8455x 0.0776 181.67 Synergistic Compound I: Cypermethrin 1：1 y = 7.1488 + 2.2064x 0.1062 240.68 Synergistic Compound I: Cypermethrin 1：10 y = 5.4548 + 1.8062x 0.5601 244.19 Synergistic Compound I: Cypermethrin 1：50 y = 3.9893 + 1.7021x 3.9243 144.22 Synergistic

[0122] From the results in Table 1, it can be seen that different ratios and dosages of Compound I and cypermethrin mixtures all have obvious synergistic effects on the activity of Plutella xylostella on cabbage.

[0123] Example 2: To verify the effects of different ratios and dosages of Compound I and beta-cypermethrin on Plutella xylostella on cabbage, an indoor toxicity determination of different ratios of Compound I and beta-cypermethrin against Plutella xylostella on cabbage was carried out. Corresponding concentrations were prepared according to the mass ratios in the table, and an indoor insecticidal test was conducted. The test results are as follows:

[0124] Table 2 Results of toxicity determination of Compound I, beta-cypermethrin and their mixtures against Plutella xylostella on cabbage

[0125]

[0126]

[0127] As can be seen from the results in Table 2, the mixed use of different ratios of Compound I and beta-cypermethrin has an obvious synergistic effect on the activity against Plutella xylostella on cabbage.

[0128] Example 3: To verify the effects of different ratios of Compound I and lambda-cyhalothrin on Plutella xylostella on cabbage, an indoor toxicity test of different ratios of Compound I and lambda-cyhalothrin against Plutella xylostella was carried out. Corresponding concentrations were prepared according to the mass ratios in the table, and an indoor insecticidal test was carried out. The test results are as follows:

[0129] Table 3 Toxicity test results of Compound I, lambda-cyhalothrin and their mixtures against Plutella xylostella on cabbage

[0130]

[0131] As can be seen from the results in Table 3, the mixed use of different ratios of Compound I and lambda-cyhalothrin has an obvious synergistic effect on the activity against Plutella xylostella on cabbage.

[0132] Example 4: To verify the effects of different ratios of Compound I and etofenprox on Plutella xylostella on cabbage, an indoor toxicity test of different ratios of Compound I and etofenprox against Plutella xylostella was carried out. Corresponding concentrations were prepared according to the mass ratios in the table, and an indoor insecticidal test was carried out. The test results are as follows:

[0133] Table 4 Toxicity test results of Compound I, etofenprox and their mixtures against Plutella xylostella on cabbage

[0134]

[0135]

[0136] As can be seen from the results in Table 4, the mixed use of different ratios of Compound I and etofenprox has an obvious synergistic effect on the activity against Plutella xylostella on cabbage.

[0137] Indoor insecticide activity test on Mythimna separata

[0138] In this test, the indoor activity of the compound against Mythimna separata was determined by the leaf-dipping method to determine the activity of the insecticidal compositions in Examples 5-7 against Mythimna separata.

[0139] Example 5: To verify the effects of different ratios of Compound I and cyfluthrin on Mythimna separata, an indoor toxicity test of different ratios of Compound I and cyfluthrin against Mythimna separata was carried out. Corresponding concentrations were prepared according to the mass ratios in the table, and an indoor insecticidal test was carried out. The test results are as follows:

[0140] Table 5 Toxicity test results of Compound I, cyfluthrin and their mixtures against Mythimna separata

[0141] Active ingredient Ratio Regression equation <![CDATA[LC 50 > Coefficient of co-toxicity Evaluation Compound I — y = 5.7178 + 2.0073x 0.4389 — — Cyfluthrin — y = 2.8070 + 2.2330x 9.5962 — — Compound I: Cyfluthrin 50：1 y = 5.9373 + 1.9494x 0.3305 135.33 Synergistic Compound I: Cyfluthrin 10：1 y = 6.2877 + 1.9997x 0.2270 211.71 Synergistic Compound I: Cyfluthrin 1：1 y = 5.5955 + 1.7118x 0.4488 187.03 Synergistic Compound I: Cyfluthrin 1：10 y = 4.6158 + 2.2752x 1.4752 224.56 Synergistic Compound I: Cyfluthrin 1：50 y = 3.5173 + 2.1062x 5.0577 134.65 Synergistic

[0142] As can be seen from the results in Table 5, the mixed use of different ratios of Compound I and lambda-cyhalothrin has an obvious synergistic effect on the activity against Mythimna separata.

[0143] Example 6: To verify the effect of different ratios of Compound I and beta-cyfluthrin on Mythimna separata, an indoor toxicity test of different ratios of Compound I and beta-cyfluthrin against Mythimna separata was carried out. Corresponding concentrations were prepared according to the mass ratios in the table for an indoor insecticidal test. The test results are as follows:

[0144] Table 6 Toxicity test results of Compound I, beta-cyfluthrin and their mixtures against Mythimna separata

[0145]

[0146]

[0147] As can be seen from the results in Table 6, the mixed use of different ratios of Compound I and beta-cyfluthrin has an obvious synergistic effect on the activity against Mythimna separata.

[0148] Example 7: To verify the effect of different ratios of Compound I and tefluthrin on Mythimna separata, an indoor toxicity test of different ratios of Compound I and tefluthrin against Mythimna separata was carried out. Corresponding concentrations were prepared according to the mass ratios in the table for an indoor insecticidal test. The test results are as follows:

[0149] Table 7 Toxicity test results of Compound I, tefluthrin and their mixtures against Mythimna separata

[0150] Active ingredient Ratio Regression equation <![CDATA[LC 50 > Coefficient of co-toxicity Evaluation Compound I — y = 5.7178 + 2.0073x 0.4389 — — Tefluthrin — y = 3.9582 + 1.5743x 4.5895 — — Compound I: Tefluthrin 50：1 y = 5.9318 + 1.9947x 0.3411 130.99 Synergistic Compound I: Tefluthrin 10：1 y = 6.0559 + 1.8083x 0.2607 183.44 Synergistic Compound I: Tefluthrin 1：1 y = 5.7132 + 1.6572x 0.3712 215.84 Synergistic Compound I: Tefluthrin 1：10 y = 4.7771 + 2.2346x 1.2581 196.16 Synergistic Compound I: Tefluthrin 1：50 y = 4.1953 + 1.7665x 2.8544 135.64 Synergistic

[0151] As can be seen from the results in Table 7, the mixed use of different ratios of Compound I and tefluthrin has an obvious synergistic effect on the activity against Mythimna separata.

[0152] Indoor insecticide activity test on Aphis gossypii

[0153] In this test, the immersion method was used to conduct an indoor activity test of the compound against Aphis gossypii to determine the activity of the insecticidal compositions in Examples 8-9 against Aphis gossypii.

[0154] Example 8: To verify the effect of different ratios of Compound I and lambda-cyhalothrin on Aphis gossypii, an indoor toxicity test of different ratios of Compound I and lambda-cyhalothrin against Aphis gossypii was carried out. Corresponding concentrations were prepared according to the mass ratios in the table for an indoor insecticidal test. The test results are as follows:

[0155] Table 8 Toxicity test results of Compound I, lambda-cyhalothrin and their mixtures against Aphis gossypii

[0156] Active ingredient Ratio Regression equation <![CDATA[LC 50 > Coefficient of co-toxicity Evaluation Compound I — y = 3.1194 + 1.5769x 15.5816 — — Beta-cyfluthrin — y = 3.3521 + 1.5879x 10.9087 — — Compound I: Beta-cyfluthrin 50：1 y = 2.7544 + 2.1017x 11.7074 131.98 Synergistic Compound I: Beta-cyfluthrin 10：1 y = 3.4179 + 1.7966x 7.5963 197.43 Synergistic Compound I: Beta-cyfluthrin 1：1 y = 3.6978 + 1.7074x 5.7901 221.64 Synergistic Compound I: Beta-cyfluthrin 1：10 y = 3.3983 + 2.1578x 5.5243 203.00 Synergistic Compound I: Beta-cyfluthrin 1：50 y = 3.0392 + 2.1981x 7.7985 140.71 Synergistic

[0157] As can be seen from the results in Table 8, the mixed use of different ratios of Compound I and lambda-cyhalothrin has an obvious synergistic effect on the activity against Aphis gossypii Glover.

[0158] Example 9: To verify the effects of different ratios of Compound I and deltamethrin on Aphis gossypii Glover, an indoor toxicity determination of different ratios of Compound I and deltamethrin against Aphis gossypii Glover was carried out. Corresponding concentrations were prepared according to the mass ratios in the table, and an indoor insecticidal test was conducted. The test results are as follows:

[0159] Table 9 Toxicity determination results of Compound I, deltamethrin and their mixtures against Aphis gossypii Glover

[0160] Active ingredient Ratio Regression equation <![CDATA[LC 50 > Coefficient of co-toxicity Evaluation Compound I — y = 3.1194 + 1.5769x 15.5816 — — Deltamethrin — y = 3.1388 + 1.8684x 9.9112 — — Compound I: Deltamethrin 50：1 y = 3.2712 + 1.7053x 10.3225 149.27 Synergistic Compound I: Deltamethrin 10：1 y = 3.6417 + 1.6873x 6.3823 232.07 Synergistic Compound I: Deltamethrin 5：1 y = 3.5617 + 1.7671x 6.5158 218.32 Synergistic Compound I: Deltamethrin 3：1 y = 3.8089 + 1.5769x 5.6930 239.45 Synergistic Compound I: Deltamethrin 1：1 y = 3.6583 + 1.8517x 5.3037 228.44 Synergistic Compound I: Deltamethrin 1：3 y = 3.6543 + 1.9371x 4.9512 220.21 Synergistic effect Compound I: Deltamethrin 1：5 y = 3.3409 + 2.3699x 5.0127 210.49 Synergistic effect Compound I: Deltamethrin 1：10 y = 3.4697 + 2.1350x 5.2089 196.78 Synergistic effect Compound I: Deltamethrin 1：50 y = 3.1788 + 2.1181x 7.2413 137.85 Synergistic effect

[0161] As can be seen from the results in Table 9, the mixed use of different ratios of Compound I and deltamethrin has an obvious synergistic effect on the activity against Aphis gossypii Glover.

[0162] Indoor determination test of the activity of pesticides against Bemisia tabaci (Gennadius) on tomato

[0163] In this test, the indoor activity of the compound against Bemisia tabaci (Gennadius) on tomato was determined by the leaf-dipping method to measure the activity of the insecticidal compositions in Examples 10 - 11 against Bemisia tabaci (Gennadius) on tomato.

[0164] Example 10: To verify the effects of different ratios of Compound I and fenpropathrin on Bemisia tabaci (Gennadius) on tomato, an indoor toxicity determination of different ratios of Compound I and fenpropathrin against Bemisia tabaci (Gennadius) on tomato was carried out. Corresponding concentrations were prepared according to the mass ratios in the table, and an indoor insecticidal test was conducted. The test results are as follows:

[0165] Table 10 Toxicity determination results of Compound I, fenpropathrin and their mixtures against Bemisia tabaci (Gennadius) on tomato

[0166] Active ingredient Ratio Regression equation <![CDATA[LC 50 > Coefficient of co-toxicity Evaluation Compound I — y = 4.0593 + 1.7553x 3.4351 — — Fenpropathrin — y = 2.2720 + 1.7479x 36.3697 — — Compound I: Fenpropathrin 50：1 y = 4.3103 + 1.6709x 2.5868 135.19 Synergistic effect Compound I: Fenpropathrin 10：1 y = 4.5576 + 1.8489x 1.7349 215.76 Synergistic effect Compound I: Fenpropathrin 1：1 y = 4.3335 + 1.6086x 2.5963 241.78 Synergistic effect Compound I: Fenpropathrin 1：10 y = 3.3673 + 1.6752x 9.4322 206.02 Synergistic effect Compound I: Fenpropathrin 1：50 y = 2.6784 + 1.8053x 19.3207 158.45 Synergistic effect

[0167] As can be seen from the results in Table 10, the mixed use of different ratios of Compound I and fenpropathrin has an obvious synergistic effect on the activity against Bemisia tabaci (Gennadius) on tomato.

[0168] Example 11: To verify the effects of different ratios of Compound I and bifenthrin on Bemisia tabaci (Gennadius) on tomato, an indoor toxicity determination of different ratios of Compound I and bifenthrin against Bemisia tabaci (Gennadius) on tomato was carried out. Corresponding concentrations were prepared according to the mass ratios in the table, and an indoor insecticidal test was conducted. The test results are as follows:

[0169] Table 11 Toxicity determination results of Compound I, bifenthrin and their mixtures against Bemisia tabaci (Gennadius) on tomato

[0170]

[0171]

[0172] As can be seen from the results in Table 11, the mixed use of different ratios of Compound I and bifenthrin has an obvious synergistic effect on the activity against Bemisia tabaci on tomatoes.

[0173] III. Field efficacy examples

[0174] In order to clarify the control effects of Compound I, pyrethroid insecticides alone and in mixtures against Mythimna separata (Walker) on corn, Plutella xylostella (L.) on cabbage, Spodoptera exigua (Hübner) on cabbage, Diaphania indica (Saunders) on cucumber, Aphis gossypii Glover on cotton, Sitobion avenae (Fabricius) on wheat, Bemisia tabaci on tomatoes and Empoasca flavescens (Fabricius) on tea, multiple efficacy tests were carried out in different regions of the country. All the preparations used were processed with reference to Preparation Examples 1-7. Taking the preparations in Table 12 as an example (other test preparations refer to the preparation examples of the same dosage form), the specific preparation method is as follows:

[0175] Table 12 Preparation of Compound I·beta-cyfluthrin suspension concentrate with different ratios

[0176]

[0177] Field efficacy test of Mythimna separata (Walker) on corn.

[0178] Test method: According to the application method specified in the "National Standard of the People's Republic of China GB / T 17980.80-2004", the medicine was applied when most of the larvae in the field were at the 2nd and 3rd instars.

[0179] Investigation method: According to the investigation method specified in the "National Standard of the People's Republic of China GB / T 17980.80-2004", 5 sampling points were taken in each plot, and 1 m 2 was taken at each point. A white cloth was laid between single-row crops, and the crops were beaten row by row to make the armyworms fall on the cloth surface, and the number of live insects was investigated. The population base of insects was investigated before application, and the number of live insects was investigated 1, 3, and 7 days after application. The calculation formula for the control effect is:

[0180]

[0181]

[0182] Diaphania indica (Saunders) on cucumber

[0183] Test method: According to the test method specified in the "National Standard of the People's Republic of China GB / T 17980.14-2000", the medicine was applied when the number of 1st-3rd instar larvae in each plot reached a certain amount.

[0184] Investigation method: According to the investigation method stipulated in the "National Standard of the People's Republic of China GB / T 17980.14 - 2000", count the number of live larvae at different instars on all crops in each plot. Conduct the initial pest population count before applying the pesticide, and investigate the number of live pests on the 1st, 3rd, and 7th days after application respectively. The formula for calculating the control effect is as follows:

[0185]

[0186]

[0187] Field efficacy test of Plutella xylostella and Spodoptera exigua on cabbage.

[0188] Test method: According to the pesticide application method stipulated in the "National Standard of the People's Republic of China GB / T 17980.13 - 2000", apply the pesticide when there are at least 1 - 3 larvae at the 3rd instar or earlier on each plant in the field.

[0189] Investigation method: According to the investigation method stipulated in the "National Standard of the People's Republic of China GB / T 17980.13 - 2000", take 5 - point samples in each plot, take 20 plants at each point, and count the number of live pests at each instar on each plant. Conduct the initial pest population count before applying the pesticide, and investigate the number of live pests on the 1st, 3rd, and 7th days after application respectively. The formula for calculating the control effect is as follows:

[0190]

[0191]

[0192] Field efficacy test of Aphis gossypii on cotton.

[0193] Test method: According to the pesticide application method stipulated in the "National Standard of the People's Republic of China GB / T 17980.75 - 2004", apply the pesticide when the cotton plants with aphids reach more than 20%.

[0194] Investigation method: According to the investigation method stipulated in the "National Standard of the People's Republic of China GB / T 17980.75 - 2004", after the cotton plants reach the 4 - leaf stage (true leaves), take 5 - point samples in each plot, fix 2 plants at each point, and fix 1 - 2 leaves with aphids in the middle part of each plant to investigate the number of aphids on the fixed leaves. Conduct the initial pest population count before applying the pesticide, and investigate the number of live pests on the 1st, 3rd, and 7th days after application respectively. The formula for calculating the control effect is as follows:

[0195]

[0196]

[0197] Field efficacy test of Sitobion avenae on wheat.

[0198] Test method: Apply pesticides according to the application method specified in "National Standard of the People's Republic of China GB / T 17980.79-2004", and apply pesticides during the peak period of wheat aphids.

[0199] Investigation method: According to the investigation method specified in "National Standard of the People's Republic of China GB / T 17980.79-2004", take 5 samples at each plot, fix 10 aphid-infected plants at each sample point, and investigate the number of aphids on the fixed plants. Investigate the initial population of insects before applying pesticides, and investigate the number of live insects on the 1st, 3rd, and 7th days after applying pesticides. The calculation formula for control efficacy (control effect) is:

[0200]

[0201]

[0202] Field efficacy test of tomato whitefly.

[0203] According to the application method specified in "Pesticide Field Efficacy Test Guidelines (GB / T17980.16-2000)", conduct foliar spraying on tomatoes.

[0204] Test method: According to the application method specified in "National Standard of the People's Republic of China (GB / T17980.16-2000)", apply pesticides when there are 2-5 whiteflies per plant.

[0205] Investigation method: According to the investigation method specified in "Pesticide Field Efficacy Test Guidelines (GB / T17980.16-2000)", demarcate 10 plants in each plot, and carefully check the back of the leaves without disturbing the insects, and record the number of live insects. Investigate the initial population of insects before applying pesticides, and conduct investigations on the 1st - 3rd days and 7th day after applying pesticides. The calculation formula for control efficacy (control effect) is:

[0206]

[0207]

[0208] Field efficacy test of Empoasca vitis.

[0209] According to the application method specified in "Pesticide Field Efficacy Test Guidelines (GB / T17980.56-2004)", conduct foliar spraying on tea plants.

[0210] Investigation method: According to the investigation method specified in "Pesticide Field Efficacy Test Guidelines (GB / T17980.56-2004)", randomly investigate the number of nymphs on 100 young leaves (generally take the second young leaf below the bud) in each plot. Investigate the initial population of insects before applying pesticides, and conduct investigations on the 1st, 3rd, and 7th days after treatment. The calculation formula for control efficacy (control effect) is:

[0211]

[0212]

[0213] Table 13 Field Efficacy Test of Compound I and Beta-cyfluthrin against Mythimna separata

[0214]

[0215] Note: Different letters after the data in the same column indicate significant differences at the P < 0.05 level by Duncan's new multiple range test. The same applies hereinafter.

[0216] In the above table, the 20% Compound I · Beta-cyfluthrin Suspension Concentrate (1:4) in Example 12 was prepared with reference to Preparation Example 3, where 20% refers to the total mass percentage of the active substances (Compound I and Beta-cyfluthrin), and 1:4 refers to the mass ratio of the two active ingredients, Compound I and Beta-cyfluthrin.

[0217] The 20% Compound I · Beta-cyfluthrin Suspension Concentrate (1:3) in Example 13 was prepared with reference to Preparation Example 3, where 20% refers to the total mass percentage of the active substances (Compound I and Beta-cyfluthrin), and 1:3 refers to the mass ratio of the two active ingredients, Compound I and Beta-cyfluthrin.

[0218] The 20% Compound I Suspension Concentrate in Comparative Example 1 was also prepared with reference to Preparation Example 3, where 20% refers to the mass percentage of the active substance, Compound I.

[0219] The following other examples and comparative examples were also prepared in a similar manner and will not be elaborated here.

[0220] From the measurement results in the table, it can be seen that when controlling Mythimna separata, the compounding of Compound I and Beta-cyfluthrin, compared with the single agent, at the same dosage of active ingredients (Comparative Examples 1 and 2 corresponding to Examples 12 - 18), the 1-day, 3-day, and 7-day control effects of the compounding of Compound I and Beta-cyfluthrin against Mythimna separata are significantly higher than those of the single agent. Among them, the 7-day control effect can still reach more than 92.52%, and the long-lasting period is relatively long.

[0221] Table 14 Field Efficacy Test of Compound I and Beta-cyfluthrin against Diaphania indica

[0222]

[0223] As can be seen from the measurement results in the table, when controlling Diaphania indica Saunders on cucumbers, the compounding of Compound I and beta-cyfluthrin, compared with the single agent, at the same dosage of active ingredient (Comparative Examples 3 and 4 corresponding to Examples 19-25), the control effects of the compounding of Compound I and beta-cyfluthrin on Diaphania indica Saunders at 1 day, 3 days and 7 days are significantly higher than those of the single agent. Among them, the control effect at 7 days can still reach more than 94.94%, and the long-lasting period is relatively long.

[0224] Table 15 Field Efficacy Test of Compound I and Beta-cypermethrin against Plutella xylostella on Cabbage

[0225]

[0226]

[0227] As can be seen from the measurement results in the table, when controlling Plutella xylostella on cabbage, the compounding of Compound I and beta-cypermethrin, compared with the single agent, at the same dosage of active ingredient (Comparative Examples 5 and 6 corresponding to Examples 26-32), the control effects of the compounding of Compound I and beta-cypermethrin on Plutella xylostella at 1 day, 3 days and 7 days are significantly higher than those of the single agent. Among them, the control effect at 7 days can still reach more than 93.05%, and the long-lasting period is relatively long.

[0228] Table 16 Field Efficacy Test of Compound I and Beta-cypermethrin against Spodoptera exigua on Cabbage

[0229]

[0230]

[0231] As can be seen from the measurement results in the table, when controlling Spodoptera exigua on cabbage, the compounding of Compound I and beta-cypermethrin, compared with the single agent, at the same dosage of active ingredient (Comparative Examples 7 and 8 corresponding to Examples 33-39), the control effects of the compounding of Compound I and beta-cypermethrin on Spodoptera exigua at 1 day, 3 days and 7 days are significantly higher than those of the single agent. Among them, the control effect at 7 days can still reach more than 94.33%, and the long-lasting period is relatively long.

[0232] Table 17 Field Efficacy Test of Compound I and Deltamethrin against Aphis gossypii Glover on Cotton

[0233]

[0234]

[0235] As can be seen from the measurement results in the table, when controlling Aphis gossypii Glover on cotton, the compounding of Compound I and deltamethrin, compared with the single agent, at the same dosage of active ingredient (Comparative Examples 9 and 10 corresponding to Examples 40-46), the control effects of the compounding of Compound I and deltamethrin on Aphis gossypii Glover at 1 day, 3 days and 7 days are significantly higher than those of the single agent. Among them, the control effect at 7 days can still reach more than 94.08%, and the long-lasting period is relatively long.

[0236] Table 18 Field Efficacy Test of Compound I and Deltamethrin against Wheat Aphids

[0237]

[0238] It can be seen from the measurement results in the table that when controlling wheat aphids, compared with the single agent, the compounding of Compound I and deltamethrin has significantly higher control effects on wheat aphids at 1 day, 3 days and 7 days under the same dosage of active ingredient (Examples 47 - 53 corresponding to Comparative Examples 11 and 12). Among them, the control effect at 7 days can still reach more than 95.15%, and the long-lasting period is relatively long.

[0239] Table 19 Field Efficacy Test of Compound I and Bifenthrin against Tomato Whiteflies

[0240]

[0241] It can be seen from the measurement results that when controlling tomato whiteflies, compared with the single agent, the compounding of Compound I and bifenthrin has significantly higher control effects on whiteflies at 1 - 3 days and 7 days under the same dosage of active ingredient (Examples 54 - 60 corresponding to Comparative Examples 13 and 14). Among them, the control effect at 7 days can still reach more than 94.08%, and the long-lasting period is relatively long.

[0242] Table 20 Field Efficacy Test of Compound I and Bifenthrin against Tea Green Leafhoppers

[0243]

[0244]

[0245] It can be seen from the measurement results in the table that when controlling tea green leafhoppers, compared with the single agent, the compounding of Compound I and bifenthrin has significantly higher control effects on tea green leafhoppers at 1 day, 3 days and 7 days under the same dosage of active ingredient (Examples 61 - 67 corresponding to Comparative Examples 15 and 16). Among them, the control effect at 7 days can still reach more than 94.98%, and the long-lasting period is relatively long.

[0246] The above describes the embodiments of the present invention. However, the present invention is not limited to the above embodiments. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A composition comprising Compound I and a pyrethroid insecticide, characterized in that, The pyrethroid insecticide is selected from one of the following: cypermethrin, beta-cypermethrin, cyhalothrin, lambda-cyhalothrin, flucythrinate, beta - flucythrinate, deltamethrin; The structure of the compound I is shown as follows, The mass ratio of the compound I to the pyrethroid insecticide is 50 to 1:1 to 50.

2. The composition according to claim 1, wherein The mass ratio of the compound I to the pyrethroid insecticide is 10 to 1:1 to 10.

3. The composition according to claim 1, wherein The mass ratio of the compound I to the pyrethroid insecticide is 50:1, 10:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:10 or 1:

50.

4. The composition according to claim 1 or 2, characterized in that, The composition further comprises at least one of deionized water, organic solvent, emulsifier, dispersant, wetting agent, thickener, defoamer, stabilizer, binder, disintegrant, antifreeze, anticaking agent, suspending agent, film-forming agent, preservative, colorant, polymer wall material, pH regulator or filler.

5. The composition according to claim 1, wherein The composition can be made into various dosage forms, and the dosage forms include wettable powder, water dispersible granule, suspension concentrate, emulsion in water, suspension seed coating agent, microcapsule suspension, microcapsule suspension - suspension concentrate, emulsifiable concentrate, microemulsion, dispersible concentrate or granule.

6. Use of the composition according to any one of claims 1 - 5 for controlling pests in agriculture or non - agriculture.

7. The use according to claim 6, characterized in that, The pests are selected from Lepidoptera, Hemiptera, Coleoptera, Thysanoptera, Diptera, mites.

8. A method for controlling pests in agriculture or non-agriculture, characterized in that, It includes applying the composition according to any one of claims 1 - 5 to plants where pests exist.

9. A composition for controlling invertebrate pests, characterized in that, It contains a biologically effective amount of the composition according to any one of claims 1 - 5 and at least one other component selected from surfactants, solid diluents and liquid diluents.

10. A method for controlling invertebrate pests, characterized in that, It includes contacting an invertebrate pest or its environment with a biologically effective amount of the composition according to any one of claims 1 - 5.

11. A spray composition, which contains the composition according to any one of claims 1 - 5 and a propellant.

12. A bait composition, which contains the composition according to any one of claims 1 - 5; one or more food materials; an optional attractant; and an optional wetting agent.

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