A screw-off sample bottle and a sample collection method

Abstract

A screw-open type sample bottle, comprising a bottle body with an open top and a bottle cap threadedly connected to the outer periphery of the top of the bottle body; wherein, the bottle cap includes a body, a through hole provided on the body, a fixed cylinder provided on the lower surface of the body and communicating with the through hole, a liquid sac provided in the fixed cylinder, a liquid outlet provided at the lower end of the fixed cylinder, a support tube connected to the liquid outlet, a needle piercing member provided in the support tube and extending to the liquid outlet, a push rod provided on the body and passing through the through hole to extend into the fixed cylinder, and a moving block provided at the lower end of the push rod and used for pressing down the liquid sac. By optimizing the structure of the bottle cap, the present invention arranges the sac for storing the preservation liquid outside the bottle for storing the sample, without contacting the sample, thus avoiding the problems of the sac interfering with the preservation of the sample and hindering the subsequent extraction of the sample, and has the advantages of simple structure, simple operation and high safety.

Description

Technical Field

[0001] The present invention belongs to the technical field of laboratory ware, and particularly relates to a screw - off sample bottle and a sample collection method. Background Art

[0002] The pathology department is one of the essential departments in a large general hospital. Its main task is to undertake pathological diagnosis during the medical process, including providing a clear pathological diagnosis for the clinic through biopsy, exfoliative and fine needle aspiration cytology examinations, and autopsy to determine the nature of the disease.

[0003] The solid sample submission bottle is a container for preserving and transporting solid samples. Its main functions are as follows: 1. Preserving samples: The solid sample submission bottle can effectively protect the sample from external contamination and damage, thus ensuring the quality and reliability of the sample. 2. Preventing sample deterioration: The solid sample submission bottle can prevent the sample from getting damp, deteriorating, and volatilizing, thus maintaining the stability and long - term reliability of the sample. 3. Facilitating transportation: The solid sample submission bottle can effectively prevent the sample from being damaged and leaking during transportation, thus ensuring that the sample reaches the destination safely. 4. Identifying samples: The solid sample submission bottle usually has functions of identification and numbering, which is convenient for tracking and managing the samples.

[0004] The general operation steps for fixing a sample submission bottle include: First, select a suitable bottle according to experimental requirements, such as a polyethylene bottle, a glass bottle, a stainless - steel bottle, or a fluoroplastic bottle, etc. Second, use tools such as a sterile spatula or pliers to take out the solid sample and put it into the bottle, paying attention to avoiding contaminating and damaging the sample. Third, seal it with a suitable sealing method, such as putting on a stopper or screwing on a bottle cap. Ensure that the bottle is sealed to avoid sample leakage and contamination. Fourth, mark information such as the name, number, and date of the sample on the bottle for future identification and management.

[0005] The prior art, such as the document with the authorization announcement number CN207254330U, discloses a closed - type double - chamber tissue specimen submission bottle assembly. It includes a bottle body with an open top and a bottle cap threadedly connected to the top of the bottle body: A filter screen with a removable edge fixedly arranged on the bottle wall is horizontally arranged in the middle and lower part of the bottle body, and a sealing film fixedly arranged on the bottle wall is horizontally arranged in the middle and upper part. A cutter extending downward for cutting the sealing film is arranged inside the bottle cap. The bottle cavity part of the bottle body below the sealing film is a liquid storage cavity for storing liquid: The submission bottle assembly further includes a bottom - piercing pumping device for piercing the bottom of the bottle body and pumping and sending liquid to the liquid storage cavity.

[0006] The working principle of the device is as follows: The preservation liquid is sealed in the liquid storage cavity under the sealing film. After opening the cap, the specimen is directly placed on the sealing film. After covering the bottle cap and rotating it to the bottom of the bottle-opening thread section, the blocking strip is broken off with greater force. The bottle cap continues to move downward, so that the bottle cap thread continues to cooperate with the film-breaking thread. At the same time, the cutter gradually moves downward close to the sealing film and starts to cut the sealing film, and the specimen drops into the preservation liquid.

[0007] Problems existing in the prior art include: The sealing film cut by the cutter is directly stored in the liquid along with the sample, which will interfere with the preservation of the sample and hinder the subsequent extraction of the sample. Summary of the Invention

[0008] In view of the above problems, the object of the present invention is to provide a screw-open type sample bottle. By optimizing the structure of the bottle cap, the capsule for storing the preservation liquid is arranged outside the bottle body for storing the sample and does not contact the sample, avoiding the problems of the capsule interfering with the preservation of the sample and hindering the subsequent extraction of the sample, and having the advantages of simple structure, simple operation and high safety.

[0009] To achieve the above object, the technical solution of the present invention is as follows:

[0010] A screw-open type sample bottle includes a bottle body with an open top and a bottle cap threadedly connected to the outer periphery of the top of the bottle body. Among them, the bottle cap includes a body, a through hole provided on the body, a fixed cylinder provided on the lower surface of the body and communicating with the through hole, a liquid capsule provided in the fixed cylinder, a liquid outlet provided at the lower end of the fixed cylinder, a support tube connected to the liquid outlet, a needle piercing member provided in the support tube and extending to the liquid outlet, a push rod provided on the body and passing through the through hole to extend into the fixed cylinder, and a moving block provided at the lower end of the push rod and used for pressing down the liquid capsule.

[0011] As a further preference of the present invention, the bottle cap further includes a fixing plate provided at the lower end of the support tube and a liquid outlet pipe provided in the fixing plate and communicating with the support tube. The opening of the liquid outlet pipe is located at the side end of the fixing plate and faces the inner wall of the bottle body.

[0012] As a further preference of the present invention, the bottle cap further includes at least two cover plates hinged to the side wall of the top of the through hole and oppositely arranged, and a channel for the push rod to pass through is provided between the cover plates.

[0013] As a further preference of the present invention, the bottle cap further includes a rotating cylinder provided on the upper surface of the body and located on the outer peripheral side of the through hole and having an open top. The height of the rotating cylinder is greater than the length of the push rod.

[0014] As a further preference of the present invention, it further includes a filter paper. A limiting strip is provided on the inner wall of the bottle body. After the bottle body is connected to the bottle cap, the limiting strip is connected to the lower surface of the fixing plate, and the filter paper is fixed between the lower surface of the fixing plate and the limiting strip.

[0015] As a further preference of the present invention, the bottle cap further includes a round block located inside the rotating cylinder and connected to the upper end of the push rod.

[0016] As a further preference of the present invention, the bottle cap further includes a reinforcing rib provided on the outer peripheral side of the rotating cylinder.

[0017] As a further preference of the present invention, a deformation groove is provided on the surface of the fixing plate away from the support tube.

[0018] The present invention also provides a method for collecting samples of a screw-open sample bottle, including the following steps: placing a solid sample in the bottle body, connecting the bottle body and the bottle cap; operating the push rod to push the moving block downward until the surface of the liquid sac is punctured by the needle member, and the preservation liquid flows into the bottle body through the liquid outlet and the support tube.

[0019] The present invention also provides another method for collecting samples of a screw-open sample bottle, including the following steps: inverting the bottle cap so that the lower surface of the fixing plate faces upward, first placing the filter paper on the fixing plate, and then placing the solid sample on the filter paper; keeping the bottle cap inverted, connecting the bottle body and the bottle cap; turning the bottle body over, operating the push rod to push the moving block downward until the surface of the liquid sac is punctured by the needle member, and the preservation liquid flows into the bottle body through the liquid outlet, the support tube and the liquid outlet pipe.

[0020] In summary, the present invention has the following beneficial effects:

[0021] For the sample bottle provided by the present invention, the sac for storing the preservation liquid is not in the bottle body for storing the sample and does not contact the sample, avoiding problems of interfering with the preservation of the sample and hindering the subsequent extraction of the sample.

[0022] The bottle cap with a complex structure in the sample bottle provided by the present invention can be recycled, and has the advantages of low operation and good economy.

[0023] The bottle cap components that are prone to contamination in the sample bottle provided by the present invention can be directly disassembled and replaced, and have the advantage of high safety. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Attached Figure 1 is a schematic structural diagram of Embodiment 1 of the present invention.

[0025] Attached Figure 2 is a schematic structural diagram of the bottle cap of Embodiment 1 of the present invention.

[0026] Appendix Figure 3 It is a schematic structural diagram of Embodiment 2 of the present invention.

[0027] Appendix Figure 4 It is a schematic structural diagram of the bottle cap of Embodiment 2 of the present invention from a bottom view angle.

[0028] Appendix Figure 5 It is a schematic structural diagram of Embodiment 3 of the present invention.

[0029] Appendix Figure 6 It is the sample collection process of Embodiment 3 of the present invention Figure 1 .

[0030] Appendix Figure 7 It is the sample collection process of Embodiment 3 of the present invention Figure 2 .

[0031] Appendix Figure 8 It is the sample collection process of Embodiment 3 of the present invention Figure 3 .

[0032] Appendix Figure 9 It is the sample collection process of Embodiment 3 of the present invention Figure 4 .

[0033] Appendix Figure 10 It is a schematic diagram of the bottle cap recycling of Embodiment 3 of the present invention. Description of the drawings:

[0035] Solid sample a, bottle body 1, bottle cap 2, filter paper 3;

[0036] Limit strip 101;

[0037] Body 201, through hole 202, fixed cylinder 203, liquid sac 204, liquid outlet 205, support tube 206, needle piercing member 207, push rod 208, moving block 209, fixing plate 210, liquid outlet pipeline 211, cover plate 212, channel 213, rotating cylinder 214, round block 215, reinforcing rib 216, deformation groove 217; Detailed implementation manners

[0038] Embodiment 1

[0039] As shown in Appendix Figure 1 and Appendix Figure 2As shown in the figure, the present invention provides a screw-open sample bottle, which includes a bottle body 1 with an open top and a bottle cap 2 threadedly connected to the outer periphery of the top of the bottle body 1. Among them, the bottle cap 2 includes a body 201, a through hole 202 provided on the body 201, a fixed cylinder 203 provided on the lower surface of the body 201 and communicating with the through hole 202, a liquid sac 204 provided in the fixed cylinder 203, a liquid outlet 205 provided at the lower end of the fixed cylinder 203, a support tube 206 connected to the liquid outlet 205, a needle piercing member 207 provided in the support tube 206 and extending to the liquid outlet 204, a push rod 208 provided on the body 201 and passing through the through hole 202 to extend into the fixed cylinder 203, and a moving block 209 provided at the lower end of the push rod 208 and used to press down the liquid sac 204.

[0040] It can be understood that the liquid sac 204 refers to a sac filled with liquid inside. The sac is made of a material that is easily deformed under pressure, and the entire sac or the part of the sac in contact with the needle piercing member 207 needs to have the characteristic of being easily punctured. At the same time, the sac also needs to have the characteristic of resisting chemical reagent corrosion, which can be specifically selected according to actual needs, so it will not be elaborated here; the liquid filled in the sac is a preservation liquid, which is specifically selected according to the solid sample to be preserved, so it will not be elaborated here. The sac and the liquid inside are prefabricated products, and no filling operation is required by medical staff or experimental personnel.

[0041] A sample collection method for a screw-open sample bottle related to the above structure includes the following steps: placing a solid sample a in the bottle body 1, connecting the bottle body 1 and the bottle cap 2; operating the push rod 208 to push the moving block 209 downward until the surface of the liquid sac 204 is punctured by the needle piercing member 207, and the preservation liquid flows into the bottle body 1 through the liquid outlet 205 and the support tube 206.

[0042] It should be noted in the above sample collection method that the first moving block 209 needs to be kept away from the liquid sac 204 when the sample bottle is in an unused state to avoid puncturing the liquid sac in advance.

[0043] In this embodiment, the bottle cap 2 further includes at least two cover plates 212 which are hingedly arranged on the top side wall of the through hole 202 and are arranged oppositely. A channel 213 for the push rod 208 to pass through is arranged between the cover plates 212. A sealing member is arranged on the inner wall of the channel 213, and the material can be selected from common materials in the art such as rubber. The advantage of such a setting is that after the sample bottle stores the sample, the bottle cap 2 can be recycled. The specific operation includes separately removing the bottle cap 2 and then pulling out the first moving block 209. At this time, the two cover plates 212 are opened, and the used liquid sac can be removed from the through hole 202. Since structures such as the fixed cylinder 203 do not come into contact with the sample, only operations such as cleaning and drying are required to complete the recycling process. When using it next time, a new liquid sac can be filled into the fixed cylinder 203. Further, a member such as a torsion spring or a damping sleeve for restoring the cover plate 212 to a horizontal state can be arranged at the hinge of the cover plate 212 and the through hole 202 to ensure that the through hole 202 remains normally closed without external force, avoiding external pollution from entering the fixed cylinder 203.

[0044] Further, since the support tube 206 and the needle piercing member 207 are directly communicated with the inside of the bottle body and there is a hidden danger of pollution, the connection between the support tube 206 and the liquid outlet 205 can be provided with a detachable connection method such as a threaded connection, so as to replace the new support tube 206 and the needle piercing member 207 during recycling.

[0045] The advantages of the device provided in this embodiment compared with the prior art are as follows: First, the sac for storing the preservation liquid is not in the bottle body for storing the sample and does not come into contact with the sample, avoiding the problems of interfering with the preservation of the sample and hindering the subsequent extraction of the sample; Second, the bottle cap with a complex structure can be recycled, and the use cost is low; Third, the bottle cap structure prone to pollution can be directly disassembled and replaced, with high safety.

[0046] Embodiment 2

[0047] In this embodiment, on the basis of Embodiment 1, the structure of the bottle cap 2 is optimized to avoid directly pouring the preservation liquid onto the solid sample and avoid the situation of liquid splashing or the sample being washed away and damaged, as shown in Figure 3 and Figure 4 shown. The specific structure includes a fixing plate 210 arranged at the lower end of the support tube 206 and a liquid outlet pipe 211 arranged in the fixing plate 210 and communicated with the support tube 206. The opening of the liquid outlet pipe 211 is located at the side end of the fixing plate 210 and faces the inner wall of the bottle body 1.

[0048] Embodiment 3

[0049] In this embodiment, on the basis of Embodiment 2, the structure is optimized, as shown in Figure 5As shown in the figure, it specifically includes: a rotating cylinder 214 provided on the upper surface of the body 201, located on the outer peripheral side of the through hole 202 and having an open top, a round block 215 located inside the rotating cylinder 214 and connected to the upper end of the push rod 208, and a reinforcing rib 216 provided on the outer peripheral side of the rotating cylinder 214. The height of the rotating cylinder 214 is greater than the length of the push rod 208. Among them, an auxiliary sleeve connected to the round block 215 can also be sleeved outside the push rod 208. The function of this auxiliary sleeve is to isolate the external environment from the channel 213, and it has a foldable effect. Specifically, a corrugated folding cylinder made of a polymer material such as polytetrafluoroethylene can be selected. The purpose of setting the rotating cylinder 214 is: firstly, to overcome the problem that the push rod 208 is easily accidentally touched in Embodiment 1 and Embodiment 2, resulting in the premature rupture of the liquid sac 204; secondly, to make it easier to unscrew the bottle cap, and to isolate the operation surface of manual operation from the internal space of the bottle body, reducing the risk of contamination; thirdly, to change the operation method, using the rotating cylinder 214 as the base and the fixing plate 210 as the placement plate, placing the sample on the fixing plate 210 first, then inverting and tightening the bottle body and then turning the bottle body over. The advantage of this setting is to reduce the probability of the sample rubbing against the inner wall of the bottle body during the placement process, and also reduce the dropping height of the sample, playing a role in protecting the sample.

[0050] In this embodiment, in order to prevent the sample from directly contacting the fixing plate 210, the sample bottle further includes a filter paper 3 for placing the sample. In order to ensure that the filter paper 3 will not fall into the preservation liquid after the bottle body is turned over, a limiting strip 101 is provided on the inner wall of the bottle body 1. The limiting strip 101 is located above the liquid level line. After the bottle body 1 is connected to the bottle cap 2, the limiting strip 101 is connected to the lower surface of the fixing plate 210, and the filter paper 3 is fixed between the lower surface of the fixing plate 210 and the limiting strip 101.

[0051] In this embodiment, a deformation groove 217 is provided on the surface of the fixing plate 210 away from the support tube 206. The purpose is to limit the placement position of the sample when it is placed, to prevent it from being blocked by the above-mentioned limiting strip 101 after entering the bottle body.

[0052] This embodiment also provides another sample collection method for the screw - off type sample bottle, as shown in Attachment Figure 6 ~Attachment Figure 9 As shown, it includes the following steps: Invert the bottle cap 2 so that the lower surface of the fixing plate 210 faces upward. First, place the filter paper 3 on the fixing plate 210, and then place the solid sample a on the filter paper 3; keep the bottle cap 2 inverted, connect the bottle body 1 to the bottle cap 2; turn the bottle body 1 over, operate the push rod 208 to push the moving block 209 downward until the surface of the liquid sac 204 is punctured by the puncturing member 207, and the preservation liquid flows into the bottle body 1 through the liquid outlet 205, the support tube 206, and the liquid outlet pipe 211.

[0053] The method for recycling the bottle cap 2 by the device in this embodiment is similar to that in Embodiment 1. As shown in the attached Figure 10 figure, the used liquid sac 204 is removed, the support tube 206 and the components connected thereto are disassembled and replaced, and other structures are used continuously after aseptic treatments such as cleaning and drying.

[0054] The specific embodiments described herein are merely illustrative of the spirit of the present invention. Those skilled in the art to which the present invention pertains can make various modifications or supplements to the described specific embodiments or use similar ways for substitution, but will not deviate from the spirit of the present invention or exceed the scope defined by the appended claims.

Claims

1. A screw-off sample bottle, characterized in that, It includes a bottle body (1) with an open top and a bottle cap (2) threadedly connected to the outer periphery of the top of the bottle body (1); wherein, the bottle cap (2) includes a body (201), a through hole (202) provided on the body (201), a fixed cylinder (203) provided on the lower surface of the body (201) and communicating with the through hole (202), a liquid sac (204) provided in the fixed cylinder (203), a liquid outlet (205) provided at the lower end of the fixed cylinder (203), a support tube (206) connected to the liquid outlet (205), a needle piercing member (207) provided in the support tube (206) and extending to the liquid outlet (205), a push rod (208) provided on the body (201) and passing through the through hole (202) to extend into the fixed cylinder (203), and a moving block (209) provided at the lower end of the push rod (208) and used to press down the liquid sac (204); the bottle cap (2) further includes a fixing plate (210) provided at the lower end of the support tube (206), and a liquid outlet pipe (211) provided in the fixing plate (210) and communicating with the support tube (206), and an opening of the liquid outlet pipe (211) is located at the side end of the fixing plate (210) and faces the inner wall of the bottle body (1); It further includes a filter paper (3), a limiting strip (101) is provided on the inner wall of the bottle body (1), after the bottle body (1) is connected to the bottle cap (2), the limiting strip (101) is connected to the lower surface of the fixing plate (210), and the filter paper (3) is fixed between the lower surface of the fixing plate (210) and the limiting strip (101).

2. The screw-off sample bottle according to claim 1, wherein, The bottle cap (2) further includes at least two cover plates (212) hinged to the top side wall of the through hole (202) and oppositely arranged, and a channel (213) for the push rod (208) to pass through is provided between the cover plates (212).

3. The screw-off sample bottle according to claim 1, wherein, The bottle cap (2) further includes a rotating cylinder (214) provided on the upper surface of the body (201) and located on the outer peripheral side of the through hole (202) and having an open top, and the height of the rotating cylinder (214) is greater than the length of the push rod (208).

4. The screw-off type sample bottle according to claim 3, characterized in that, The bottle cap (2) further includes a round block (215) located in the rotating cylinder (214) and connected to the upper end of the push rod (208).

5. The screw-off type sample bottle according to claim 3, characterized in that, The bottle cap (2) further includes a reinforcing rib (216) provided on the outer peripheral side of the rotating cylinder (214).

6. The screw-off type sample bottle according to claim 1, characterized in that, A deformation groove (217) is provided on the surface of the fixing plate (210) away from the support tube (206).

7. The sample collection method of a screw - off sample bottle as claimed in claim 1, wherein, It includes the following steps: Invert the bottle cap (2) so that the lower surface of the fixing plate (210) faces upward. First, place the filter paper (3) on the fixing plate (210), and then place the solid sample (a) on the filter paper (3). While keeping the bottle cap (2) inverted, connect the bottle body (1) to the bottle cap (2). Flip the bottle body (1) and operate the push rod (208) to push the moving block (209) downward until the surface of the liquid sac (204) is punctured by the needle puncturing member (207), and the preservation liquid flows into the bottle body (1) through the liquid outlet (205), the support tube (206), and the liquid outlet pipe (211).

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