An oxygenator upper cover structure, an oxygenator shell and an oxygenator

Abstract

The embodiment of the present application provides an oxygenator upper cover structure, an oxygenator shell and an oxygenator, which comprise an upper cover body, a blood inlet pipe, a liquid outlet pipe and an air inlet pipe; a first chamber is arranged on the upper cover body; a first isolation ring, a second isolation ring and a third isolation ring are arranged in the first chamber; the blood inlet pipe penetrates the first isolation ring, the second isolation ring and the third isolation ring from outside to inside in sequence, and a space surrounded by the blood inlet pipe and the third isolation ring is in communication; the liquid outlet pipe is in communication with a passage between the second isolation ring and the third isolation ring; the air inlet pipe is in communication with a passage between the first isolation ring and the second isolation ring; the first isolation ring, the second isolation ring and the third isolation ring are concentrically arranged, a first distance between the first isolation ring and the second isolation ring in a first direction is greater than a second distance between the first isolation ring and the second isolation ring in a second direction, the first direction is an extension direction of the liquid outlet pipe from inside to outside, and the first direction is opposite to the second direction. Through the embodiment of the present application, the oxygenation efficiency can be improved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of extracorporeal oxygenation, in particular to an oxygenator upper cover structure, an oxygenator shell and an oxygenator. BACKGROUND

[0002] Extracorporeal membrane oxygenation (ECMO) is to lead the blood in the body out of the body, through the special material artificial heart-lung bypass oxygenation, and then inject into the patient's arterial or venous system, to play a partial heart-lung replacement role, and maintain the oxygenation of human body organs and tissues. The oxygenator is an important component in the ECMO system, which provides the function of maintaining the temperature of extracorporeal blood and executing the function of blood oxygenation. There are mainly three circulation paths in the oxygenator: a blood path, in which blood enters the internal part of the oxygenator through a specific channel, and is warmed by the oxygenator temperature change film area to maintain a constant blood temperature; a gas path, in which oxygen penetrates into the blood through the oxygenation film silk in the oxygenation area, while carbon dioxide in the venous blood penetrates into the oxygenation film silk from the blood; and a water path, in which liquid with constant temperature provides heat energy to the blood through the temperature change film silk to maintain the temperature of the blood in the extracorporeal circulation pipeline.

[0003] The dispersion of the existing oxygenator gas path is lack of research, and how to improve the oxygenation efficiency of the gas path is always pursued by people. SUMMARY

[0004] In order to solve or alleviate all or part of the above problems, the present application provides an oxygenator upper cover structure, an oxygenator shell and a membrane oxygenator.

[0005] In a first aspect, the present application provides an oxygenator upper cover structure, comprising an upper cover body, a blood inlet pipe, a liquid outlet pipe and a gas inlet pipe.

[0006] The upper cover body is provided with a first chamber, and the first chamber is provided with a first isolation ring, a second isolation ring and a third isolation ring.

[0007] The blood inlet pipe penetrates the first isolation ring, the second isolation ring and the third isolation ring from outside to inside in sequence, and the space surrounded by the blood inlet pipe and the third isolation ring is in communication.

[0008] The liquid outlet pipe is in communication with the channel between the second isolation ring and the third isolation ring, and the gas inlet pipe is in communication with the channel between the first isolation ring and the second isolation ring.

[0009] The first distance between the first isolation ring and the second isolation ring in a first direction is greater than the second distance between the first isolation ring and the second isolation ring in a second direction, the first direction is the extension direction of the liquid outlet pipe from inside to outside, and the first direction is opposite to the second direction.

[0010] Compared with the prior art, the embodiment of the application provides an oxygenator upper cover structure, which is characterized in that the oxygenator upper cover structure comprises an upper cover body, a blood inlet pipe, a liquid outlet pipe and an air inlet pipe; the upper cover body is provided with a first cavity, and the first cavity is provided with a first isolation ring, a second isolation ring and a third isolation ring; the blood inlet pipe penetrates the first isolation ring, the second isolation ring and the third isolation ring from outside to inside in sequence, and a space surrounded by the blood inlet pipe and the third isolation ring is in communication; the liquid outlet pipe is in communication with a passage between the second isolation ring and the third isolation ring, and the air inlet pipe is in communication with a passage between the first isolation ring and the second isolation ring; a first distance between the first isolation ring and the second isolation ring in a first direction is greater than a second distance between the first isolation ring and the second isolation ring in a second direction, the first direction is an extension direction of the liquid outlet pipe from inside to outside, and the first direction is opposite to the second direction. According to the embodiment of the application, different shapes of flow resistance zones and directions of air flow of the air inlet are arranged in the oxygenation area of the upper cover. Under the condition of the same blood flow direction and flow rate, the oxygenation efficiency is different. According to the embodiment of the application, the oxygenation efficiency of blood can be improved, and the formation of thrombus can be reduced.

[0011] In a second aspect, the embodiment of the application provides an oxygenator shell, which comprises a lower cover structure, a shell body and the oxygenator upper cover structure of any one of the first aspect.

[0012] The shell comprises a lower cover structure, a shell body and the oxygenator upper cover structure of the first aspect.

[0013] The upper cover structure and the lower cover structure are arranged at two ends of the shell body.

[0014] A blood outlet pipe is arranged on the shell body at a position corresponding to the blood inlet pipe, and the blood outlet pipe and the blood inlet pipe are arranged on the same side.

[0015] The lower cover structure comprises a lower cover body, a liquid inlet pipe, an air outlet pipe and an air outlet, and the liquid inlet pipe, the air outlet pipe and the air outlet are arranged on the lower cover body; the liquid inlet pipe and the air outlet pipe are parallel to each other and arranged on the same side, and the air outlet is arranged in a middle region of the liquid inlet pipe and the air outlet pipe.

[0016] The liquid outlet pipe and the liquid inlet pipe are parallel to each other and arranged on the same side, and the air inlet pipe and the air outlet pipe are parallel to each other and arranged on the same side.

[0017] In a third aspect, the embodiment of the application further provides an oxygenator comprising the oxygenator shell of the second aspect.

[0018] Compared with the prior art, the beneficial effects of the technical solutions provided by the second aspect and the third aspect are the same as those of the first aspect, and will not be described here again. Attached Figure Description

[0019] Figure 1 A perspective view of the internal structure of a membrane oxygenator cover provided in this application embodiment;

[0020] Figure 2 A perspective view of the external structure of a membrane oxygenator cover provided in this application embodiment;

[0021] Figure 3 A three-dimensional structural view of a membrane oxygenator provided in an embodiment of this application;

[0022] Figure 4 A perspective view of the internal structure of the lower cover of a membrane oxygenator provided in this application embodiment;

[0023] Figure 5 This is a perspective view of the external structure of a membrane oxygenator lower cover structure provided in an embodiment of this application. Detailed Implementation

[0024] To enable those skilled in the art to better understand the technical solutions of this application, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort should fall within the scope of protection of this application.

[0025] It should be noted that the terms "first," "second," etc., in the specification, claims, and accompanying drawings of this application are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate so that the embodiments of this application described herein can be implemented in orders other than those illustrated or described herein. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover non-exclusive inclusion; for example, a process, method, system, product, or apparatus that comprises a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such processes, methods, products, or apparatus.

[0026] Firstly, such as Figure 1 and Figure 2 As shown, this application provides an oxygenator cover structure, including a cover body 09, an inlet tube 08, a drain tube 10, and an air inlet tube 11;

[0027] The upper cover body 09 is provided with a first chamber, and the first chamber is provided with a first isolation ring 12, a second isolation ring 13 and a third isolation ring 14; the blood inlet pipe 08 is vertically arranged with the liquid outlet pipe 10 and the gas inlet pipe 06.

[0028] The blood inlet pipe 08 penetrates the first isolation ring 12, the second isolation ring 13 and the third isolation ring 14 from outside to inside in sequence, and the blood inlet pipe 08 is in communication with a space surrounded by the third isolation ring 14;

[0029] The liquid outlet pipe is in communication with a passage between the second isolation ring 13 and the third isolation ring 14, and the gas inlet pipe 08 is in communication with a passage between the first isolation ring 12 and the second isolation ring 13;

[0030] A first distance between the first isolation ring 12 and the second isolation ring 13 in a first direction is greater than a second distance between the first isolation ring 12 and the second isolation ring 13 in a second direction, the first direction is an extension direction of the liquid outlet pipe 10 from inside to outside, and the first direction is opposite to the second direction. In the embodiment of the application, it is found through experiments that the dispersion path and speed of the oxygen gas entering the upper cover region are different, and the oxygenation efficiency of the blood is also different. The oxygenation efficiency can be obtained by testing and calculating the concentrations of oxygen and carbon dioxide through the gas inlet pipe 11 and the gas outlet pipe of the oxygenator. Specifically, the oxygen gas starts to diffuse from the outside of the side wall edge of the upper cover body 09 or from the inside of the oxygenation region, and the shape of the diffusion zone isolation band has a greater influence on the blood oxygenation efficiency than the starting position of the diffusion. When the first distance between the first isolation ring 12 and the second isolation ring 13 in the first direction is greater than the second distance between the first isolation ring 12 and the second isolation ring 13 in the second direction, the blood oxygenation efficiency is optimal. The gas starts to diffuse from the inside to the outside in the passage between the first isolation ring 12 and the second isolation ring 13. The applicant has verified through experiments that the blood oxygenation efficiency is poorer when the cross-sectional area of the first isolation ring 12 is circular than when the cross-sectional area of the first isolation ring 12 is oval.

[0031] A third distance between the first isolation ring 12 and the second isolation ring 13 in a third direction is the same as a fourth distance between the first isolation ring 12 and the second isolation ring 12 in a fourth direction; the third direction is perpendicular to the first direction, and the third direction is opposite to the fourth direction. As a preferred embodiment of the application, the first isolation ring 12 and the second isolation ring 13 are concentrically arranged.

[0032] As a preferred embodiment of the present application, the height of the first isolation ring 12 is less than the height of the second isolation ring 13, the third isolation ring 14 and the side wall of the upper cover body 09. The embodiment of the present application can improve the oxygenation efficiency by setting the height of the first isolation ring 12 to be lower. The present application designs a new oxygen diffusion path for the upper cover, in which the oxygen first diffuses through the inner ring of the gas path and then diffuses to the outer ring. The temporary retention of the gas can improve the oxygenation efficiency.

[0033] As a preferred embodiment of the present application, the cross-sectional area surrounded by the first isolation ring 12 and the second isolation ring 13 is 30-40% of the cross-sectional area of the entire gas path, i.e. the cross-sectional area of the space surrounded by the side wall of the upper cover body and the second isolation ring. Preferably, the cross-sectional area is 35%. Through experiments, it is found that, in the ventilation area of the upper cover structure, the oxygenation efficiency is different under the same blood flow direction and flow rate conditions by setting different shapes of the flow resistance area and the direction of the gas flow of the gas inlet pipe. The embodiment of the present application can improve the oxygenation efficiency of the blood.

[0034] As a preferred embodiment of the present application, the liquid discharge pipe 10 and the gas inlet pipe 11 are arranged in parallel and on the same side. The blood inlet pipe 08 is arranged perpendicularly to the liquid discharge pipe 10 and the gas inlet pipe 11.

[0035] As a preferred embodiment of the present application, the liquid discharge pipe 20 is arranged between the blood inlet pipe 08 and the gas inlet pipe 22.

[0036] In a second aspect, as shown in Figure 3 The present application also provides an oxygenator shell, which comprises a lower cover structure, a shell body 15 and the upper cover structure of the oxygenator according to the first aspect.

[0037] The upper cover structure and the lower cover structure are arranged at both ends of the shell body 15.

[0038] A blood outlet pipe 16 is arranged on the shell body 15 at a position corresponding to the blood inlet pipe 08. The blood outlet pipe 16 is arranged on the same side as the blood inlet pipe 08.

[0039] As a preferred embodiment of the present application, the blood outlet pipe 16 is arranged at the end of the shell body 15 close to the lower cover structure.

[0040] As shown in Figure 3 and Figure 4 The lower cover structure comprises a lower cover body 01, a liquid inlet pipe 06, an exhaust pipe 07 and an exhaust port 05.

[0041] The liquid inlet pipe 06, the exhaust pipe 07 and the exhaust port 05 are arranged on the lower cover body 01; the liquid outlet pipe 10 is parallel to the liquid inlet pipe 06 and in the same direction, and the air inlet pipe 11 is parallel to the exhaust pipe 07 and in the same direction; the positions of the liquid outlet pipe 20, the air inlet pipe 11 and the blood inlet pipe 08 of the upper cover structure are matched with the positions of the exhaust pipe 07, the liquid inlet pipe 06 and the exhaust port 05 of the lower cover structure of the oxygenator, which is beneficial to improve the oxygenation efficiency of the oxygenator on blood.

[0042] The lower cover body 01 is provided with a second chamber, and the second chamber is provided with a fourth isolation ring 03, a fifth isolation ring 04 and a plurality of rib structures 02; the fourth isolation ring 04 is arranged at the periphery of the fifth isolation ring 04, and the plurality of rib structures 02 are arranged at the periphery of the fourth isolation ring 03.

[0043] The liquid inlet pipe 06 penetrates the side wall of the lower cover body 01 and the fourth isolation ring 04 from outside to inside, and the liquid inlet pipe 06 is in communication with the passages between the fourth isolation ring 03 and the fifth isolation ring 04; one end of the liquid inlet pipe 06 is arranged on the fourth isolation ring 03, and the exhaust pipe 07 is arranged on the side wall of the lower cover body 01 and is in communication with the passages between the side wall of the lower cover body 01 and the fourth isolation ring 03.

[0044] The liquid inlet pipe 06 is arranged parallel to the exhaust pipe 07 and on the same side, and the exhaust port 05 is arranged in the middle region of the liquid inlet pipe 06 and the exhaust pipe 07.

[0045] In the embodiment, the plurality of rib structures 02 have heat dissipation and flow guiding effects, and the pre-discharged carbon dioxide is heat-dissipated and flow-guided by the plurality of rib structures 02 to be discharged from the exhaust pipe 07; in the embodiment, seven rib structures 02 are preferably arranged.

[0046] The shortest distance from the exhaust port 05 to the center of the lower cover body 01 is a first distance, and the vertical distance between the tangent lines of the exhaust port 05 to the lower cover body 01 is a second distance; the first distance is greater than the second distance. The position of the exhaust port 05 is experimentally verified, and the positions of the exhaust ports B1 / B2 / B3 are only examples of the embodiment; under different oxygen flow rates, the total CO2 removal amount and the total O2 exchange amount of the exhaust ports located at B1 / B2 / B3 are measured, and it is found that the gas exchange related data of the exhaust port located at B1 is obviously higher than that of the exhaust ports located at B2 and B3; since the outlet of the entire oxygenator gas path encounters cold and produces condensed water, the exhaust port 05 can also discharge the condensed water generated at the outlet of the gas path.

[0047] In the embodiment of the present application, the upper cover structure and the lower cover structure of the oxygenator are concentrically arranged, and the upper cover structure and the lower cover structure are circular in cross section. In specific use, the temperature-variable membrane filaments are arranged between the second isolation ring 13 and the third isolation ring 14, one end of the temperature-variable membrane filaments is connected to the space between the second isolation ring 13 and the third isolation ring 14 of the upper cover body, the other end of the temperature-variable membrane filaments is connected to the space between the fourth isolation ring 03 and the fifth isolation ring 04 of the lower cover body, and the annular columnar temperature-variable region formed by a plurality of temperature-variable membrane filaments flows with heat exchange medium such as water. The heat exchange medium enters the temperature-variable membrane region channel between the fourth isolation ring 03 and the fifth isolation ring 04 through the liquid inlet pipe 06 of the lower cover, and flows out from the liquid outlet pipe 10 in communication with the space between the third isolation ring 14 and the second isolation ring 13 of the upper cover body, so as to heat and keep warm the blood. Similarly, the oxygenation membrane filaments are arranged outside the temperature-variable region, forming an annular columnar oxygenation region, and high-purity oxygen flows from the space between the second isolation ring 13 and the third isolation ring 14 to the communication between the side wall of the lower cover body 01 and the fourth isolation ring 03, and then flows through the channel between the side wall of the lower cover body 01 and the fourth isolation ring 03, and then is discharged through the exhaust pipe 07.

[0048] As a preferred embodiment of the present application, a plurality of the rib structures 02 are vertically arranged in the second chamber, the rib structures 02 are long strip structures, the heights of the plurality of rib structures 02 are the same, and the plurality of rib structures 02 are lower than the height of the side wall of the lower cover body 01 and the height of the second isolation ring 03. In the embodiment of the present application, the plurality of rib structures 02 are vertically arranged in the second chamber, which can make the contact area between the discharged carbon dioxide gas after blood oxygenation and the rib structures 02 larger, and is beneficial to the flow guiding effect of the plurality of rib structures 02. The rib structures 02 can make the carbon dioxide flow to the exhaust pipe 07 and the exhaust port 05 more uniformly and quickly, and the “steady flow” effect is more beneficial to the flow of oxygen in the oxygenator, so that the oxygenation efficiency of the oxygenator is better.

[0049] As a preferred embodiment of the present application, the two adjacent rib structures 02 are not connected at the head and tail and are arranged at intervals, which is beneficial to the flow guiding and discharging of the oxygenated gas.

[0050] As a preferred embodiment of the present application, one end of each rib structure 02 is connected to the side wall of the lower cover body 01, and the other end of each rib structure 02 has a preset distance from the side wall of the lower cover body 01, which can make the gas form a rotating flow along the rib direction, and the gas can be discharged more smoothly and quickly to the outlet, avoiding the retention of the exchanged gas.

[0051] As a preferred embodiment of the present application, the liquid inlet pipe 06 is symmetrically provided with a muscle structure 02 on both sides. The liquid inlet pipe 06 is symmetrically provided with a muscle structure 02 on both sides, which is conducive to the flow of gas on both sides of the liquid inlet pipe 06.

[0052] As a preferred embodiment of the present application, the liquid inlet pipe 06 is parallel to the exhaust pipe 07 and is arranged on the same side. The exhaust pipe 07 has a predetermined distance between the other end of the muscle structure 02 adjacent to it. The exhaust pipe 07 has a predetermined distance between the other end of the muscle structure 02 adjacent to it, which is conducive to better exhaust.

[0053] Preferably, the liquid inlet pipe 06 is radially arranged along the lower cover body 01. The liquid inlet pipe 06 and the exhaust pipe 07 are arranged on the horizontal plane of the lower cover body 01.

[0054] In a third aspect, the embodiments of the present application also provide an oxygenator, which comprises the oxygenator shell of the second aspect.

[0055] Compared with the prior art, the beneficial effects of the technical solutions of the second aspect and the third aspect are the same as those of the first aspect, which will not be repeated here.

[0056] Although the present application has been described in detail with general description and specific embodiments herein, some modifications or improvements can be made to the present application on the basis of the present application, which is obvious to those skilled in the art. Therefore, these modifications or improvements made on the basis of not deviating from the spirit of the present application, all belong to the scope of protection required by the present application.

Claims

1. An oxygenator top cover structure, characterized by, The upper cover body is provided with a first chamber, and the first chamber is provided with a first isolation ring, a second isolation ring and a third isolation ring; The blood inlet pipe penetrates the first isolation ring, the second isolation ring and the third isolation ring from outside to inside in sequence, and a space surrounded by the blood inlet pipe and the third isolation ring is in communication; the height of the first isolation ring is smaller than the height of the side wall of the second isolation ring, the third isolation ring and the upper cover body; The liquid outlet pipe is in communication with the passage between the second isolation ring and the third isolation ring, and the air inlet pipe is in communication with the passage between the first isolation ring and the second isolation ring; the first distance between the first isolation ring and the second isolation ring in a first direction is greater than the second distance between the first isolation ring and the second isolation ring in a second direction, the first direction is the extension direction of the liquid outlet pipe from inside to outside, and the second direction is the direction of the liquid outlet pipe extending from inside to the direction opposite to the first direction. The third distance between the first isolation ring and the second isolation ring in a third direction is the same as the fourth distance between the first isolation ring and the second isolation ring in a fourth direction; the third direction is the extension direction of the blood inlet pipe from inside to outside, and the fourth direction is the direction of the blood inlet pipe extending from inside to the direction opposite to the third direction.

2. An oxygenator cover structure as claimed in claim 1, wherein The second isolation ring and the third isolation ring are concentrically arranged.

3. An oxygenator cover structure as defined in claim 1, wherein The cross-sectional area of the space surrounded by the first isolation ring and the second isolation ring is 30-40% of the cross-sectional area of the space surrounded by the side wall of the upper cover body and the second isolation ring.

4. An oxygenator cover structure as defined in claim 1, wherein The blood inlet pipe is vertically arranged with the liquid outlet pipe and the air inlet pipe, and the liquid outlet pipe and the air inlet pipe are arranged in parallel and on the same side.

5. An oxygenator cover structure as defined in claim 1, wherein The liquid outlet pipe is arranged between the blood inlet pipe and the air inlet pipe.

6. An oxygenator cover structure as defined in claim 1, wherein The shell comprises a lower cover structure, a shell body and an oxygenator upper cover structure as claimed in any one of claims 1 to 6; 7. An oxygenator housing, characterized by The upper cover structure and the lower cover structure are arranged at two ends of the shell body; A blood outlet pipe is arranged on the shell body at a position corresponding to the blood inlet pipe, and the blood outlet pipe and the blood inlet pipe are arranged on the same side; The lower cover structure comprises a lower cover body, a liquid inlet pipe, an air outlet pipe and an air outlet, and the liquid inlet pipe, the air outlet pipe and the air outlet are arranged on the lower cover body; the liquid inlet pipe and the air outlet pipe are arranged in parallel and on the same side, and the air outlet is arranged in the middle region of the liquid inlet pipe and the air outlet pipe; The liquid outlet pipe and the liquid inlet pipe are arranged in parallel and on the same side, and the air inlet pipe and the air outlet pipe are arranged in parallel and on the same side. The blood outlet pipe is arranged at the end of the shell body close to the lower cover structure.

8. An oxygenator housing as claimed in claim 7, wherein The lower cover body is provided with a second chamber, and the second chamber is provided with a fourth isolation ring, a fifth isolation ring and a plurality of rib structures; 9. An oxygenator housing as claimed in claim 7, wherein, The fourth isolation ring is arranged at the periphery of the fifth isolation ring, and a plurality of rib structures are arranged at the periphery of the fourth isolation ring; the heights of the plurality of rib structures are the same, and the heights of the plurality of rib structures are lower than the height of the side wall of the lower cover body and the height of the fourth isolation ring; ​ The liquid inlet pipe penetrates the side wall of the lower cover body and the fourth isolation ring from outside to inside, and is in communication with the passage between the fourth isolation ring and the fifth isolation ring, and one end of the liquid inlet pipe is arranged on the fourth isolation ring; the exhaust pipe is in communication with the passage between the side wall of the lower cover body and the fourth isolation ring; and the exhaust pipe is arranged on the side wall of the lower cover body.

10. An oxygenator housing as claimed in claim 9, wherein The diameter of the lower cover body where the exhaust port is located is perpendicular to the liquid inlet pipe and the exhaust pipe.

11. An oxygenator housing as claimed in claim 9, wherein The shortest distance from the exhaust port to the center of the lower cover body is a first distance, and the vertical distance between the tangent lines from the exhaust port to the lower cover body is a second distance, and the first distance is greater than the second distance.

12. An oxygenator housing as claimed in claim 9, wherein, The two adjacent muscle structures are not connected at the head and tail and are arranged at intervals.

13. An oxygenator housing as claimed in claim 9, wherein, One end of each muscle structure is connected to the side wall of the lower cover body, and the other end of each muscle structure has a preset distance from the side wall of the lower cover body.

14. An oxygenator housing as in claim 9, wherein, The liquid inlet pipe is symmetrically distributed with a muscle structure on both sides.

15. The oxygenator housing of claim 9, wherein the liquid inlet pipe is radially disposed along the lower cover body.

16. An oxygenator characterized by, An oxygenator housing as claimed in any one of claims 7 to 15.

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