A kind of feed for preventing and treating diarrhea in suckling pigs and its preparation method

Abstract

The present invention discloses a feed for preventing and treating diarrhea in suckling pigs and a preparation method thereof, relating to the field of feeds. Among them, the feed for preventing and treating diarrhea in suckling pigs includes a basic feed, an organic acid and an additive; the additive includes a core layer and a coating layer wrapped around the outer peripheral side of the core layer; the core layer is made of a core material, and the core material includes mulberry leaf powder, sunflower disc powder, lecithin and bromelain, and the weight ratio of the mulberry leaf powder, sunflower disc powder, lecithin and bromelain is (10-25):(5-20):0.2:1; the coating layer is made of the coating, and the coating includes carboxymethyl chitosan, alginate, calcium chloride and water, and the weight ratio of the carboxymethyl chitosan, alginate, calcium chloride and water is (1-2):(1-2):4:100. The suckling pig feed in this application effectively utilizes the sunflower disc, reduces the waste of resources, and the above suckling pig feed has the advantages of being easy for suckling pigs to digest, being able to reduce the diarrhea rate of suckling pigs, and having good storage stability and not being prone to mildew.

Description

Technical Field

[0001] The present invention relates to the field of feeds, and in particular to a feed for preventing and treating diarrhea in suckling pigs and a preparation method thereof. Background Art

[0002] Diarrhea in suckling pigs is a typical multi-factorial disease. There are a wide variety of pathogens causing diarrhea in suckling pigs, the disease nature is complex, and there are mixed infections of multiple pathogens. For a long time, diarrhea in suckling pigs has been an important cause of growth retardation and high mortality in suckling pigs. Therefore, the prevention and treatment of diarrhea in suckling pigs has always been a world-wide problem attracting much attention.

[0003] In addition, sunflower plates are rich in various natural compounds and trace elements, such as chlorogenic acid, flavonoids, volatile oils, manganese, zinc, etc., which have very extensive physiological activities and pharmacological activities. If sunflower plates can be applied to the feed for suckling pigs, it can effectively reduce the waste of resources. Summary of the Invention

[0004] In order to reduce the waste of sunflower plate resources and at the same time improve the problem of easy diarrhea in suckling pigs, the present application provides a feed for preventing and treating diarrhea in suckling pigs and a preparation method thereof.

[0005] In the first aspect, a feed for preventing and treating diarrhea in suckling pigs provided by the present application adopts the following technical solution:

[0006] A feed for preventing and treating diarrhea in suckling pigs, comprising the following raw materials in parts by weight:

[0007] Basic feed: 200 parts

[0008] Organic acid: 5 - 10 parts

[0009] Additive: 20 - 40 parts

[0010] The additive comprises a core layer and a coating layer wrapped around the outer peripheral side of the core layer;

[0011] The core layer is made of a core material, and the core material comprises mulberry leaf powder, sunflower plate powder, lecithin and bromelain, and the weight ratio of the mulberry leaf powder, sunflower plate powder, lecithin and bromelain is (10 - 25):(5 - 20):0.2:1;

[0012] The coating layer is made of the coating, and the coating comprises carboxymethyl chitosan, alginate, calcium chloride and water, and the weight ratio of the carboxymethyl chitosan, alginate, calcium chloride and water is (1 - 2):(1 - 2):4:100;

[0013] The weight ratio of the core material to the coating is (8 - 15):1.

[0014] Mulberry leaf powder can improve the immune ability of suckling pigs and reduce the risk of virus infection. Sunflower disc powder can, on the one hand, improve the palatability of suckling pig feed, and on the other hand, cooperate with organic acids to promote the growth of beneficial bacteria in the intestines of suckling pigs, while inhibiting the growth of harmful bacteria, thus effectively improving the intestinal environment of suckling pigs, reducing the occurrence of diarrhea problems in suckling pigs, and promoting the healthy growth of suckling pigs.

[0015] However, during the practical process, the inventor found that when directly adding mulberry leaf powder and sunflower disc powder to the basic feed for suckling pigs, there are the following two problems: (1) The digestion and absorption rate of the feed by suckling pigs decreases, and the weight gain rate drops. (2) After the feed is stored for a long time, the ability to improve the diarrhea problem of suckling pigs decreases, and to a certain extent, it will also increase the diarrhea rate of suckling pigs because the feed is prone to mildew.

[0016] To solve the above problems, the inventor added lecithin and bromelain to the mulberry leaf powder and sunflower disc powder, and mixed a specific proportion of mulberry leaf powder, sunflower disc powder, lecithin and bromelain as the core material, and coated a layer of coating outside the core material to make an additive, and then added the additive and organic acids to the basic feed. Among them, the addition of lecithin and bromelain can not only improve the problem of low digestion and absorption rate caused by adding mulberry leaf powder and sunflower disc powder to the feed, but also cooperate with the coating to reduce the mildew probability of mulberry leaf powder and sunflower disc powder. However, the stability of lecithin and bromelain is poor, and it is necessary to coat the core material with a coating made of a specific proportion of carboxymethyl chitosan, alginate, calcium chloride and water to improve the stability of lecithin and bromelain during the feed pelletizing process.

[0017] In summary, the suckling pig feed in this application effectively utilizes the sunflower disc, reduces the waste of resources, and the above-mentioned suckling pig feed has the advantages of being easy for suckling pigs to digest, being able to reduce the diarrhea rate of suckling pigs, and having good storage stability and not being prone to mildew.

[0018] Optionally, the weight ratio of the mulberry leaf powder, sunflower disc powder, lecithin and bromelain is (15 - 20):(10 - 15):0.2:1.

[0019] When the weight ratio of the mulberry leaf powder, sunflower disc powder, lecithin and bromelain is within the range of (15 - 20):(10 - 15):0.2:1, it can further reduce the diarrhea rate of suckling pigs, and at the same time, further improve the storage stability of the suckling pig feed.

[0020] Optionally, the weight ratio of the mulberry leaf powder, sunflower disc powder, lecithin and bromelain is 17:13:0.2:1.

[0021] When the weight ratio of mulberry leaf powder, sunflower disc powder, lecithin and bromelain is 17:13:0.2:1, under the condition that other conditions are the same, it can further reduce the diarrhea rate of piglets, and at the same time, further improve the storage stability of piglet feed.

[0022] Optionally, the preparation method of the additive comprises the following steps:

[0023] Uniformly mix mulberry leaf powder, sunflower disc powder, lecithin and bromelain to obtain the core material;

[0024] Dissolve carboxymethyl chitosan, alginate and calcium chloride in water, then heat to 40-50 °C and stir for 1-3 h to obtain the coating; uniformly mix the core material and the coating in proportion, and then dry at 50-60 °C to obtain the additive.

[0025] Carboxymethyl chitosan and alginate are crosslinked under the promotion of calcium chloride to obtain a coating material, which has good toughness and small porosity, and is more conducive to improving the storage stability of piglet feed.

[0026] Optionally, the mixing method of the mulberry leaf powder, sunflower disc powder, lecithin and bromelain is ball milling. During the ball milling process, the rotation speed of the ball milling is 50-100 r / min, the ball-to-material ratio is 1:(1-1.5), and the ball milling time is 0.5-1 h.

[0027] When using the ball milling method to mix mulberry leaf powder, sunflower disc powder, lecithin and bromelain to prepare the core material, it can further improve the storage stability of piglet plastic.

[0028] Optionally, when preparing the coating, heat to 40-50 °C and perform ultrasonic treatment for 1-3 h.

[0029] When preparing the coating material, adding ultrasonic treatment can further improve the storage stability of piglet feed.

[0030] Optionally, the organic acid includes taurine and sorbic acid, and the weight ratio of taurine to sorbic acid is 1:(3-4).

[0031] When the organic acid is selected as taurine and sorbic acid, it is more conducive to improving the intestinal environment of piglets and further reducing the diarrhea rate of piglets.

[0032] Optionally, based on the basic feed, the basic feed includes 80-100 parts by weight of soybean meal powder, 60-80 parts by weight of corn flour, 10-20 parts by weight of wheat flour, and 20-30 parts by weight of rice bran powder.

[0033] In a second aspect, a preparation method of a diarrhea-preventing piglet feed provided by the present application adopts the following technical solution:

[0034] A preparation method of a piglet feed for preventing and treating diarrhea, comprising the following steps:

[0035] Cook and cool the basic feed to obtain a prefabricated feed;

[0036] Uniformly mix the prefabricated feed with organic acids and additives, and then granulate to obtain a piglet feed for preventing and treating diarrhea.

[0037] The piglet feed prepared by the above method has the characteristics of being more easily digestible and having a high weight gain rate, which is beneficial to reducing the diarrhea rate of piglets.

[0038] Optionally, during the cooking process, the temperature is controlled at 90 - 100 °C, and the steam pressure is controlled at 0.1 - 0.3 MPa.

[0039] Cooking the basic feed in this way is beneficial to improving the palatability and digestion and absorption rate of the piglet feed.

[0040] In summary, the technical solution of this application has at least the following beneficial effects:

[0041] 1. Adding organic acids and an additive including a core layer and a coating layer to the basic feed at the same time, and the core layer is selected as a mixture of mulberry leaf powder, sunflower disc powder, lecithin and bromelain in a specific ratio, and the coating layer is a coating prepared from carboxymethyl chitosan, alginate, calcium chloride and water, which can make the piglet feed have the advantages of being easy for piglets to digest, being able to reduce the diarrhea rate of piglets, and having good storage stability and not being prone to mildew.

[0042] 2. When the weight ratio of mulberry leaf powder, sunflower disc powder, lecithin and bromelain is in the range of (15 - 20):(10 - 15):0.2:1, it can further reduce the diarrhea rate of piglets, and at the same time, further improve the storage stability of the piglet feed. Description of the Drawings

[0043] Figure 1 is a structural schematic diagram of the additive of this application.

[0044] Description of the reference numerals:

[0045] 1. Core material layer; 2. Coating layer. Detailed Description of the Embodiment

[0046] The following further details this application in combination with specific experiments. Among them, the deacetylation degree of the carboxymethyl chitosan used in this application is 95%, and the viscosity of the 1% aqueous solution of sodium alginate is 1800 mPa·s.

[0047] Preparation Example

[0048]

Preparation Example 1

[0049] An additive, such as Figure 1, including a core material layer 1 and a coating layer 2 wrapped around the outer peripheral side of the core material layer 1.

[0050] In this preparation example:

[0051] The core material layer 1 is made from a core material, and the core material includes 10 kg of mulberry leaf powder, 20 kg of sunflower disc powder, 0.2 kg of lecithin, and 1 kg of bromelain;

[0052] The coating layer 2 is made from a coating, and the coating includes 1.5 kg of carboxymethyl chitosan, 1.5 kg of sodium alginate, 4 kg of calcium chloride, and 100 kg of water.

[0053] In this preparation example, the preparation method of the additive includes the following steps:

[0054] Stir the mulberry leaf powder, sunflower disc powder, lecithin, and bromelain evenly to obtain the core material;

[0055] Dissolve the carboxymethyl chitosan, sodium alginate, and calcium chloride in water, then heat up to 45 °C and stir for 2 h to obtain the coating;

[0056] Mix the core material and the coating evenly according to a weight ratio of 12:1, and then dry at 55 °C to obtain the additive.

[0057]

Preparation Example 2

[0058] An additive, different from

Preparation Example 1

[0059] The core material includes 15 kg of mulberry leaf powder, 15 kg of sunflower disc powder, 0.2 kg of lecithin, and 1 kg of bromelain.

[0060]

Preparation Example 3

[0061] An additive, different from

Preparation Example 1

[0062] The core material includes 17 kg of mulberry leaf powder, 13 kg of sunflower disc powder, 0.2 kg of lecithin, and 1 kg of bromelain.

[0063]

Preparation Example 4

[0064] An additive, different from

Preparation Example 1

[0065] The core material includes 20 kg of mulberry leaf powder, 10 kg of sunflower disc powder, 0.2 kg of lecithin, and 1 kg of bromelain.

[0066]

Preparation Example 5

[0067] An additive, different from

Preparation Example 1

[0068] The core material includes 25 kg of mulberry leaf powder, 5 kg of sunflower disc powder, 0.2 kg of lecithin, and 1 kg of bromelain.

[0069]

Preparation Example 6

[0070] An additive, which is different from that in

Preparation Example 3

[0071] In this preparation example, the preparation method of the additive includes the following steps:

[0072] Ball-mill and mix the mulberry leaf powder, sunflower disc powder, lecithin, and bromelain. The rotation speed of ball-milling is 75 r / min, the ball-to-material ratio is 1:1.2, and the ball-milling time is 1 h to obtain the core material;

[0073] Dissolve carboxymethyl chitosan, sodium alginate, and calcium chloride in water, then heat up to 45 °C and stir for 2 h to obtain the coating;

[0074] Uniformly mix the core material and the coating at a weight ratio of 12:1, and then dry at 55 °C to obtain the additive.

[0075]

Preparation Example 7

[0076] An additive, which is different from that in

Preparation Example 3

[0077] In this preparation example, the preparation method of the additive includes the following steps:

[0078] Stir the mulberry leaf powder, sunflower disc powder, lecithin, and bromelain evenly to obtain the core material;

[0079] Dissolve carboxymethyl chitosan, sodium alginate, and calcium chloride in water, then heat up to 45 °C and ultrasonicate for 2 h to obtain the coating;

[0080] Uniformly mix the core material and the coating at a weight ratio of 12:1, and then dry at 55 °C to obtain the additive.

[0081]

Preparation Example 8

[0082] An additive, which is different from that in

Preparation Example 3

[0083] In this preparation example, the preparation method of the additive includes the following steps:

[0084] Ball-mill and mix the mulberry leaf powder, sunflower disc powder, lecithin, and bromelain. The rotation speed of ball-milling is 75 r / min, the ball-to-material ratio is 1:1.2, and the ball-milling time is 1 h to obtain the core material;

[0085] Dissolve carboxymethyl chitosan, sodium alginate, and calcium chloride in water, then heat up to 45 °C and ultrasonicate for 2 h to obtain the coating;

[0086] The core material and the coating are uniformly mixed at a weight ratio of 12:1, and then dried at 55 °C to obtain the additive.

[0087]

Preparation Example 9

[0088] An additive, which is different from that in

Preparation Example 3

[0089] In this preparation example, the preparation method of the additive includes the following steps:

[0090] Mulberry leaf powder, sunflower disc powder, lecithin and bromelain are ball-milled and mixed. The rotation speed of the ball milling is 500 r / min, the ball-to-material ratio is 1:1.2, and the ball milling time is 1 h to obtain the core material;

[0091] Carboxymethyl chitosan, sodium alginate and calcium chloride are dissolved in water, and then the temperature is raised to 45 °C and ultrasonicated for 2 h to obtain the coating;

[0092] The core material and the coating are uniformly mixed at a weight ratio of 12:1, and then dried at 55 °C to obtain the additive.

[0093] Comparative Preparation Example

[0094]

Comparative Preparation Example 1

[0095] An additive is made by uniformly mixing 10 kg of mulberry leaf powder and 20 kg of sunflower disc powder.

[0096]

Comparative Preparation Example 2

[0097] An additive is made by uniformly stirring 10 kg of mulberry leaf powder, 20 kg of sunflower disc powder, 0.2 kg of lecithin and 1 kg of bromelain.

[0098]

Comparative Preparation Example 3

[0099] An additive, such as Figure 1 , includes a core material layer 1 and a coating layer 2 wrapped around the outer peripheral side of the core material layer 1.

[0100] Among them:

[0101] The core material layer 1 is made of the core material, and the core material includes 10 kg of mulberry leaf powder and 20 kg of sunflower disc powder;

[0102] The coating layer 2 is made of the coating, and the coating includes 1.5 kg of carboxymethyl chitosan, 1.5 kg of sodium alginate, 4 kg of calcium chloride and 100 kg of water.

[0103] In this preparation example, the preparation method of the additive includes the following steps:

[0104] Stir the mulberry leaf powder and the sunflower disc powder evenly to obtain the core material;

[0105] Dissolve carboxymethyl chitosan, sodium alginate, and calcium chloride in water, then heat to 45°C and stir for 2 hours to obtain the coating.

[0106] Mix the core material and the coating evenly at a weight ratio of 12:1, and then dry at 55°C to obtain the additive.

[0107]

Comparative Preparation Example 4

[0108] An additive, such as Figure 1 , includes a core material layer 1 and a coating layer 2 wrapped around the outer peripheral side of the core material layer 1.

[0109] Among them:

[0110] The core material layer 1 is made from the core material, and the core material includes 10 kg of mulberry leaf powder, 20 kg of sunflower disc powder, and 1.2 kg of lecithin;

[0111] The coating layer 2 is made from the coating, and the coating includes 1.5 kg of carboxymethyl chitosan, 1.5 kg of sodium alginate, 4 kg of calcium chloride, and 100 kg of water.

[0112] In this preparation example, the preparation method of the additive includes the following steps:

[0113] Stir the mulberry leaf powder, sunflower disc powder, and lecithin evenly to obtain the core material;

[0114] Dissolve carboxymethyl chitosan, sodium alginate, and calcium chloride in water, then heat to 45°C and stir for 2 hours to obtain the coating;

[0115] Mix the core material and the coating evenly at a weight ratio of 12:1, and then dry at 55°C to obtain the additive.

[0116]

Comparative Preparation Example 5

[0117] An additive, such as Figure 1 , includes a core material layer 1 and a coating layer 2 wrapped around the outer peripheral side of the core material layer 1.

[0118] Among them:

[0119] The core material layer 1 is made from the core material, and the core material includes 10 kg of mulberry leaf powder, 20 kg of sunflower disc powder, and 1.2 kg of bromelain;

[0120] The coating layer 2 is made from the coating, and the coating includes 1.5 kg of carboxymethyl chitosan, 1.5 kg of sodium alginate, 4 kg of calcium chloride, and 100 kg of water.

[0121] In this preparation example, the preparation method of the additive includes the following steps:

[0122] Stir the mulberry leaf powder, sunflower disc powder, and bromelain evenly to obtain the core material;

[0123] Dissolve carboxymethyl chitosan, sodium alginate, and calcium chloride in water, then heat to 45°C and stir for 2 h to obtain the coating.

[0124] Mix the core material and the coating evenly at a weight ratio of 12:1, and then dry at 55°C to obtain the additive.

[0125]

Comparative Preparation Example 6

[0126] An additive, such as Figure 1 , includes a core material layer 1 and a coating layer 2 wrapped around the outer peripheral side of the core material layer 1.

[0127] In this preparation example:

[0128] The core material layer 1 is made from the core material, and the core material includes 10 kg of mulberry leaf powder, 20 kg of sunflower disc powder, 0.2 kg of lecithin, and 1 kg of bromelain;

[0129] The coating layer 2 is made from the coating, and the coating includes 3 kg of carboxymethyl chitosan, 4 kg of calcium chloride, and 100 kg of water.

[0130] In this preparation example, the preparation method of the additive includes the following steps:

[0131] Stir the mulberry leaf powder, sunflower disc powder, lecithin, and bromelain evenly to obtain the core material;

[0132] Dissolve carboxymethyl chitosan and calcium chloride in water, then heat to 45°C and stir for 2 h to obtain the coating;

[0133] Mix the core material and the coating evenly at a weight ratio of 12:1, and then dry at 55°C to obtain the additive.

[0134]

Comparative Preparation Example 7

[0135] An additive, such as Figure 1 , includes a core material layer 1 and a coating layer 2 wrapped around the outer peripheral side of the core material layer 1.

[0136] In this preparation example:

[0137] The core material layer 1 is made from the core material, and the core material includes 10 kg of mulberry leaf powder, 20 kg of sunflower disc powder, 0.2 kg of lecithin, and 1 kg of bromelain;

[0138] The coating layer 2 is made from the coating, and the coating includes 3 kg of sodium alginate, 4 kg of calcium chloride, and 100 kg of water.

[0139] In this preparation example, the preparation method of the additive includes the following steps:

[0140] Stir the mulberry leaf powder, sunflower disc powder, lecithin, and bromelain evenly to obtain the core material;

[0141] After dissolving sodium alginate and calcium chloride in water, the temperature was raised to 45 °C and stirred for 2 h to prepare the coating;

[0142] The core material and the coating were uniformly mixed at a weight ratio of 12:1 and then dried at 55 °C to obtain the additive.

[0143] Example

[0144]

Example 1

[0145] A piglet feed for preventing and treating diarrhea, comprising the following raw materials:

[0146] Base feed: 200 kg

[0147] Organic acid: 5 kg

[0148] Additive: 20 kg.

[0149] Among them, the base feed comprises the following raw materials:

[0150] Soybean meal powder: 80 kg

[0151] Corn flour: 80 kg

[0152] Wheat flour: 10 kg

[0153] Rice bran powder: 30 kg.

[0154] The organic acid selected is taurine.

[0155] The additive selected is the additive prepared in

Preparation Example 1

[0156] In this example, the preparation method of the piglet feed comprises the following steps:

[0157] The base feed was cooked and cooled to obtain the prefabricated material; during the cooking process, the temperature was controlled at 95 °C and the steam pressure was controlled at 0.2 MPa;

[0158] The prefabricated material was uniformly mixed with the organic acid and the additive, and then granulated to obtain the piglet feed for preventing and treating diarrhea.

[0159]

Example 2

[0160] A piglet feed for preventing and treating diarrhea, comprising the following raw materials:

[0161] Base feed: 200 kg

[0162] Organic acid: 7.5 kg

[0163] Additive: 30 kg.

[0164] Among them, the base feed comprises the following raw materials:

[0165] Soybean meal powder: 90 kg

[0166] Corn flour: 70 kg

[0167] Wheat flour: 15 kg

[0168] Rice bran powder: 25 kg.

[0169] The organic acid selected is taurine.

[0170] The additive selected is the additive prepared in [Preparation Example 1].

[0171] In this embodiment, the preparation method of the piglet feed comprises the following steps:

[0172] Cook and cool the basic feed to obtain a prefabricated feed; during the cooking process, the temperature is controlled at 95 °C and the steam pressure is controlled at 0.2 MPa;

[0173] Uniformly mix the prefabricated feed with the organic acid and the additive, and then granulate to obtain the piglet feed for preventing and treating diarrhea.

[0174]

Example 3

[0175] A piglet feed for preventing and treating diarrhea, comprising the following raw materials:

[0176] Basic feed: 200 kg

[0177] Organic acid: 10 kg

[0178] Additive: 40 kg.

[0179] Among them, the basic feed comprises the following raw materials:

[0180] Soybean meal powder: 100 kg

[0181] Corn flour: 60 kg

[0182] Wheat flour: 20 kg

[0183] Rice bran powder: 20 kg.

[0184] The organic acid selected is taurine.

[0185] The additive selected is the additive prepared in [Preparation Example 1].

[0186] In this embodiment, the preparation method of the piglet feed comprises the following steps:

[0187] Cook and cool the basic feed to obtain a prefabricated feed; during the cooking process, the temperature is controlled at 95 °C and the steam pressure is controlled at 0.2 MPa;

[0188] Mix the prefabricated material with organic acid and additives evenly, and then granulate to obtain the piglet feed for preventing and treating diarrhea.

[0189]

Example 4

[0190] A piglet feed for preventing and treating diarrhea, which is different from

Example 2

[0191] The additive is the additive obtained in

Preparation Example 2

[0192]

Example 5

[0193] A piglet feed for preventing and treating diarrhea, which is different from

Example 2

[0194] The additive is the additive obtained in

Preparation Example 3

[0195]

Example 6

[0196] A piglet feed for preventing and treating diarrhea, which is different from

Example 2

[0197] The additive is the additive obtained in

Preparation Example 4

[0198]

Example 7

[0199] A piglet feed for preventing and treating diarrhea, which is different from

Example 2

[0200] The additive is the additive obtained in

Preparation Example 5

[0201]

Example 8

[0202] A piglet feed for preventing and treating diarrhea, which is different from

Example 5

[0203] The additive is the additive obtained in

Preparation Example 6

[0204]

Example 9

[0205] A piglet feed for preventing and treating diarrhea, which is different from

Example 5

[0206] The additive is the additive obtained in

Preparation Example 7

[0207]

Example 10

[0208] A piglet feed for preventing and treating diarrhea, which is different from

Example 5

[0209] The additive is the additive obtained in

Preparation Example 8

[0210]

Example 11

[0211] A piglet feed for preventing and treating diarrhea, different from [Example 5] in that:

[0212] The additive is the additive prepared in [Preparation Example 9].

[0213]

Example 12

[0214] A piglet feed for preventing and treating diarrhea, different from [Example 10] in that:

[0215] The organic acid is sorbic acid.

[0216]

Example 13

[0217] A piglet feed for preventing and treating diarrhea, different from [Example 10] in that:

[0218] The organic acid is a mixture of taurine and sorbic acid, and the weight ratio of taurine to sorbic acid is 1:4.

[0219]

Example 14

[0220] A piglet feed for preventing and treating diarrhea, different from [Example 10] in that:

[0221] The organic acid is a mixture of taurine and sorbic acid, and the weight ratio of taurine to sorbic acid is 4:1.

[0222]

Example 15

[0223] A piglet feed for preventing and treating diarrhea, different from [Example 13] in that:

[0224] Taurine is replaced with an equal amount of citric acid.

[0225]

Example 16

[0226] A piglet feed for preventing and treating diarrhea, different from [Example 13] in that:

[0227] Sorbic acid is replaced with an equal amount of citric acid.

[0228] Control example

[0229]

Control Example 1

[0230] A piglet feed, different from Example [2] in that:

[0231] Taurine and the additive in [Preparation Example 1] are not added.

[0232]

Control Example 2

[0233] A piglet feed, different from Example [2] in that:

[0234] Taurine is replaced with an equal amount of the additive in [Preparation Example 1].

[0235]

Comparative Example 3

[0236] A piglet feed, which is different from Example 【2】 in that:

[0237] The additive in

Preparation Example 1

Comparative Preparation Example 1

[0238]

Comparative Example 4

[0239] A piglet feed, which is different from Example 【2】 in that:

[0240] The additive in

Preparation Example 1

Comparative Preparation Example 2

[0241]

Comparative Example 5

[0242] A piglet feed, which is different from Example 【2】 in that:

[0243] The additive in

Preparation Example 1

Comparative Preparation Example 3

[0244]

Comparative Example 6

[0245] A piglet feed, which is different from Example 【2】 in that:

[0246] The additive in

Preparation Example 1

Comparative Preparation Example 4

[0247]

Comparative Example 7

[0248] A piglet feed, which is different from Example 【2】 in that:

[0249] The additive in

Preparation Example 1

Comparative Preparation Example 5

[0250]

Comparative Example 8

[0251] A piglet feed, which is different from Example 【2】 in that:

[0252] The additive in

Preparation Example 1

Comparative Preparation Example 6

[0253]

Comparative Example 9

[0254] A piglet feed, which is different from Example 【7】 in that:

[0255] The additive in

Preparation Example 1

Comparative Preparation Example 7

[0256] Performance detection test

[0257] Experiment 1

[0258] 1. Experimental subjects: 20-day-old three-way crossbred pigs that were weaned for 7 days, of uniform size, similar body weight, and similar health status.

[0259] 2. Number of experiments: 2,500 heads.

[0260] 3. Feeding method: Divide the 2,500 pigs into 25 groups, with 100 pigs in each group, and feed them the suckling pig feed in Examples 1-16 and Comparative Examples 1-9 (sealed and stored for 30 days). Among them, 800 g of suckling pig feed is added at 8:00, 11:00, 14:00, 17:00, and 20:00 every day, and the test period is 14 days.

[0261] 4. Data recording: Calculate the average daily feed intake, average daily weight gain, feed-to-meat ratio, protein digestibility, diarrhea rate (the proportion of suckling pigs with diarrhea), and survival rate, and record them in Table 1 below.

[0262] Table 1

[0263]

[0264]

[0265] Experiment 2

[0266] (1) Experimental subjects: 20-day-old three-way crossbred pigs that were weaned for 7 days, of uniform size, similar body weight, and similar health status.

[0267] (2) Number of experiments: 1,700 heads.

[0268] (3) Feeding method: Divide the 1,700 pigs into 17 groups, with 100 pigs in each group, and feed them the suckling pig feed in Example 2, Examples 4-6, Examples 8-11, and Comparative Examples 1-9 (sealed and stored for 360 days). Among them, 800 g of suckling pig feed is added at 8:00, 11:00, 14:00, 17:00, and 20:00 every day, and the test period is 14 days.

[0269] (4) Data recording: Calculate the average daily feed intake, average daily weight gain, feed-to-meat ratio, protein digestibility, diarrhea rate (the proportion of suckling pigs with diarrhea), and survival rate, and record them in Table 2 below.

[0270] Table 2

[0271]

[0272] Compared with Example 2, in Comparative Example 1, no organic acid and additive were added; in Comparative Example 2, the organic acid was replaced by an additive; in Comparative Example 3, the additive consisted only of a mixture of mulberry leaf powder and sunflower disc powder; in Comparative Example 4, the additive consisted only of a mixture of mulberry leaf powder, sunflower disc powder, lecithin, and bromelain; in Comparative Example 5, lecithin and bromelain were not added to the core material of the additive; in Comparative Example 6, bromelain was not added to the core material of the additive; in Comparative Example 7, lecithin was not added to the core material of the additive; in Comparative Example 8, sodium alginate was not added to the coating of the additive; in Comparative Example 9, carboxymethyl chitosan was not added to the coating of the additive.

[0273] Among them, it can be seen from the data in Table 1 that when piglets were fed the piglet feed in Comparative Examples 1-2, the protein digestibility was high but the diarrhea rate was also high; when piglets were fed the piglet feed in Comparative Examples 3-7, the diarrhea rate of the piglets was improved compared with that in Comparative Example 1. However, the protein digestibility of the piglets in the piglet feed was significantly reduced, and the effective utilization rate of the feed decreased; when piglets were fed the piglet feed in Comparative Examples 8-9, the diarrhea rate of the piglets was improved compared with that in Comparative Example 1, and the protein digestibility of the piglets in the piglet feed decreased, but the decline was less than that in Comparative Examples 3-7. It can be seen that the piglet feed in Example 2 can effectively improve the diarrhea rate and protein digestibility of piglets at the same time, which depends on the common cooperation of the organic acid, the structure and composition of the additive.

[0274] In addition, it can be seen from the data in Table 2 that compared with feeding the piglet feed in Comparative Examples 1-9, when piglets were fed the piglet feed in Example 2, the increase in the diarrhea rate of the piglets was lower, indicating that the storage stability of the piglet feed in Example 2 is better than that of the piglet feed in Comparative Examples 1-9. It can be seen that the improvement of the storage stability of the piglet feed in Example 2 also depends on the common cooperation of the organic acid, the structure and composition of the additive.

[0275] Combining Example 2 with Examples 4-7 and the data in Tables 1-2, it can be seen that when the weight ratio of mulberry leaf powder, sunflower disc powder, lecithin, and bromelain is in the range of (15-20):(10-15):0.2:1, it can further reduce the diarrhea rate of piglets and at the same time further improve the storage stability of piglet feed.

[0276] Combined with Example 5 and Examples 8 - 11 and the data in Tables 1 - 2, it can be seen that the difference between Examples 8 - 11 and Example 5 lies in the preparation method of the additive. Among them, compared with the suckling pig feed in Example 5, when the suckling pigs are fed with the suckling pig feed in Examples 8 - 10, the increase rate of the diarrhea rate of the suckling pigs is lower, and when the suckling pigs are fed with the suckling pig feed in Example 10, the increase rate of the diarrhea rate of the suckling pigs is the lowest. Thus, it can be seen that the preparation method of the additive will also affect the storage stability of the suckling pig feed. Among them, the raw materials of the core material are mixed by ball milling, and the ball milling speed is controlled within the range of 50 - 100 r / min, which is beneficial to improving the storage stability of the suckling pig feed. In addition, ultrasonic-assisted reaction is more beneficial to improving the storage stability of the suckling pig feed during the coating preparation process.

[0277] Combined with Example 10 and Examples 12 - 16 and the data in Table 1, it can be seen that the difference between Examples 12 - 16 and Example 10 lies in the selection of organic acids. Among them, combined with the data in Table 1, it can be seen that when the organic acid is a mixture of taurine and sorbic acid, and the weight ratio of taurine to sorbic acid is within the range of 1:(3 - 4), it is more beneficial to improve the intestinal environment of suckling pigs, thereby further reducing the diarrhea rate of suckling pigs.

[0278] This specific embodiment is only an interpretation of the present application, and it is not a limitation of the present application. Those skilled in the art can make modifications without creative contributions to this specific embodiment according to needs after reading this specification, but as long as it is within the scope of the claims of the present application, it is protected by the patent law.

Claims

1. A feed for preventing and treating diarrhea in suckling pigs, characterized in that: Comprising the following raw materials in parts by weight: Basic feed: 200 parts Organic acid: 5 - 10 parts Additive: 20 - 40 parts The additive includes a core layer (1) and a coating layer (2) wrapped around the outer peripheral side of the core layer (1); The core layer (1) is made from a core material, and the core material includes mulberry leaf powder, sunflower disc powder, lecithin, and bromelain. The weight ratio of the mulberry leaf powder, sunflower disc powder, lecithin, and bromelain is (10 - 25):(5 - 20):0.2:1; The coating layer (2) is made from the coating, and the coating includes carboxymethyl chitosan, alginate, calcium chloride, and water. The weight ratio of the carboxymethyl chitosan, alginate, calcium chloride, and water is (1 - 2):(1 - 2):4:100; The weight ratio of the core material to the coating is (8 - 15):

1.

2. The anti-diarrhea piglet feed according to claim 1, characterized in that: The weight ratio of the mulberry leaf powder, sunflower disc powder, lecithin, and bromelain is (15 - 20):(10 - 15):0.2:

1.

3. The anti-diarrhea piglet feed according to claim 2, characterized in that: The weight ratio of the mulberry leaf powder, sunflower disc powder, lecithin, and bromelain is 17:13:0.2:

1.

4. A kind of feed for preventing and treating diarrhea in suckling pigs according to claim 1, characterized in that: The preparation method of the additive includes the following steps: Uniformly mix the mulberry leaf powder, sunflower disc powder, lecithin, and bromelain to obtain the core material; Dissolve the carboxymethyl chitosan, alginate, and calcium chloride in water, then heat to 40 - 50 °C and stir for 1 - 3 h to obtain the coating; Uniformly mix the core material and the coating in proportion, and then dry at 50 - 60 °C to obtain the additive.

5. A feed for preventing and treating diarrhea in suckling pigs according to claim 4, characterized in that: When preparing the core material, the mixing method of the mulberry leaf powder, sunflower disc powder, lecithin, and bromelain is ball milling. During the ball milling process, the rotation speed of the ball milling is 50 - 100 r / min, the ball - to - material ratio is 1:(1 - 1.5), and the ball milling time is 0.5 - 1 h.

6. The anti-diarrhea piglet feed according to claim 4, characterized in that: When preparing the coating, heat to 40 - 50 °C and perform ultrasonic treatment for 1 - 3 h.

7. The anti - diarrhea piglet feed according to claim 1, characterized in that: The organic acid includes taurine and sorbic acid, and the weight ratio of taurine to sorbic acid is 1:(3 - 4).

8. A piglet feed for preventing and treating diarrhea according to any one of claims 1-7, characterized in that: Based on the basic feed, the basic feed includes 80 - 100 parts by weight of soybean meal powder, 60 - 80 parts by weight of corn flour, 10 - 20 parts by weight of wheat flour, and 20 - 30 parts by weight of rice bran powder.

9. A method for preparing a feed for preventing and treating diarrhea in suckling pigs according to any one of claims 1-8, characterized in that: Including the following steps: Cook and cool the basic feed to obtain a pre - material; Uniformly mix the pre - material with the organic acid and the additive, and then granulate to obtain the anti - diarrhea piglet feed.

10. The preparation method of a piglet feed for preventing and treating diarrhea according to claim 9, wherein: During the cooking process, the temperature is controlled at 90 - 100 °C, and the steam pressure is controlled at 0.1 - 0.3 MPa.

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