A composition with skin whitening and brightening function and its application

Abstract

This invention belongs to the field of cosmetic technology, specifically relating to compositions with skin-whitening and brightening functions and their applications. The skin-whitening and brightening composition of this invention includes: white truffle extract, black truffle extract, vitamin C derivative, melanin transport inhibitor, and collagen supplement. This invention combines five ingredients—white truffle extract, black truffle extract, soluble collagen, vitamin C ethyl ether, and niacinamide—to comprehensively improve the excessive melanin synthesis, inflammatory response, and collagen degradation processes caused by UV radiation through multiple pathways, resulting in a composition with skin-whitening and brightening functions.

Description

Technical Field

[0001] This invention belongs to the field of cosmetic technology, specifically relating to compositions with whitening and brightening functions and their applications. Background Art

[0002] Melanin granules synthesized by melanocytes in the basal layer of the epidermis play a crucial role in determining skin color and photoprotection. In human skin, melanin is an effective absorber of ultraviolet (UV) radiation, accumulating around the cell nucleus to protect skin cells from UV damage. However, when melanin is abnormally overproduced, it is transferred from melanocytes to keratinocytes and then through layers of metastasis, eventually accumulating on the skin surface, causing visible pigmentation. Abnormal pigment accumulation can lead to freckles, sunspots, and dark spots, and may even induce melanoma, impacting mental well-being and quality of life. Furthermore, UV radiation can induce the production of leukotrienes, prostaglandins, and other inflammatory substances, triggering various inflammatory responses in the skin through signal transduction and regulatory mechanisms, including erythema, swelling, and thermal effects. Simultaneously, activation of IL-1α increases the expression and activity of matrix metalloproteinases, further degrading collagen and elastin, leading to decreased skin elasticity and firmness, and signs of skin aging.

[0003] Chinese patent CN108578261B discloses a water-soluble whitening composition formulation, comprising four whitening active ingredients: 4-(1-phenylethyl)-1,3-benzenediol, white truffle extract, mulberry root extract, and ferulic acid, as well as water, poloxamer, polyethylene glycol (PEG-based), a moisturizer, a skin feel modifier, and a preservative system. The moisturizer involves the use of niacinamide. This composition not only achieves good whitening efficacy and low skin irritation, but also ensures that the compounded whitening active ingredients are stably soluble in the aqueous phase, avoiding an oily skin feel. However, this composition uses poloxamer, and the synthesis of poloxamer easily introduces byproducts and secondary byproducts such as ethylene glycol, diethylene glycol, and triethylene glycol, all of which have certain irritant and toxic properties.

[0004] Chinese patent CN108714110B discloses a skin whitening and freckle-removing complex. Its active ingredients include phenylethyl resorcinol, ginger root extract, white truffle extract, bisabolol, and small molecule active peptides. It can effectively remove freckles and whiten the skin by inhibiting tyrosinase, exerting antioxidant, anti-inflammatory, and anti-glycation effects, thereby blocking the formation and deepening of skin pigmentation. However, while this composition considers melanin synthesis and other factors leading to increased melanin production, it does not address the transport and degradation processes of melanin.

[0005] Chinese patent CN111870554B discloses a skin-whitening composition and its preparation method. The oil phase of the whitening composition is a mixture of phenylethyl resorcinol, oils, emulsifiers, and stabilizers; the aqueous phase consists of carnosine, nicotinamide, white truffle extract, mulberry bark extract, and water. This whitening composition exhibits good encapsulation efficiency, melanin inhibition effect, and low toxicity. However, this composition only addresses the entire melanin synthesis pathway and does not consider other factors besides ultraviolet radiation that lead to increased melanin production, such as skin inflammation and free radicals.

[0006] Chinese patent CN102327199B discloses a cosmetic nanostructure with active ingredients including vitamin C and its derivatives, niacinamide, and arbutin. This composition provides a nanostructure capable of stably encapsulating bioactive ingredients and improving skin absorption. However, the active ingredients in the composition are only effective for melanin synthesis and transport, and the whitening ingredient arbutin carries the risk of introducing hydroquinone, which has toxic side effects. Summary of the Invention

[0007] The purpose of this invention is to provide a composition with skin whitening and brightening functions.

[0008] Another object of the present invention is to provide applications of the above-described composition.

[0009] The composition with skin whitening and brightening function according to a specific embodiment of the present invention comprises, by weight: 0.5-20 parts of white truffle extract, 1-20 parts of black truffle extract, 1-10 parts of vitamin C derivative, 5-20 parts of melanin transport inhibitor, and 0.1-10 parts of collagen supplement.

[0010] Truffles are large, tuberous fungi belonging to the ascomycetes family. Truffles not only have a unique aroma but also possess physiological activity and medicinal value. Common types of truffles on the market include Indian truffles, black truffles, white truffles, and summer truffles. White truffles are rich in bioactive substances, including α-androstanol and polysaccharides, and are also high in protein, vitamins, and fatty acids, making them highly valuable for both nutrition and health. Black truffles are rich in amino acids, vitamins, sterols, and trace elements.

[0011] Vitamin C ethyl ether is a derivative of vitamin C. It has an amphiphilic structure that is both lipophilic and hydrophilic, making it easier for the vitamin C to penetrate the skin.

[0012] Niacinamide is an industry-recognized ingredient that can reduce melanin in the skin.

[0013] Soluble collagen can inhibit the production of intracellular ROS in human immortalized keratinocytes and promote the secretion of type I collagen precursors; it can also promote collagen synthesis in human skin fibroblasts by inhibiting mitogen-activated protein kinase and activating the TGF-β signaling pathway.

[0014] In the composition of this invention, vitamin C ethyl ether is selected to inhibit melanin production, white truffle extract to inhibit the synthesis and degradation of melanosomes, niacinamide to inhibit melanin transport, black truffle extract to alleviate UV-induced inflammation, excessive ROS accumulation, type I collagen degradation, and melanin synthesis, and soluble collagen to inhibit melanin production and collagen degradation. Thus, these five components comprehensively improve the excessive melanin synthesis, inflammatory response, and collagen degradation processes caused by UV radiation through multiple pathways. Therefore, a composition with white truffle extract, black truffle extract, soluble collagen, vitamin C ethyl ether, and niacinamide is constructed to brighten skin tone through multiple pathways and in a comprehensive manner.

[0015] The composition with skin whitening and brightening function according to a specific embodiment of the present invention further includes 1-1.5 parts of preservative, 0.15-1.5 parts of thickener, and 45-85 parts of water.

[0016] According to a specific embodiment of the present invention, the composition having skin whitening and brightening function includes one or more of p-hydroxyacetophenone, 1,2-pentanediol, 1,2-hexanediol, octyl glycol, raspberry ketone, and phenoxyethanol as preservatives.

[0017] According to a specific embodiment of the present invention, the composition having skin whitening and brightening function includes one or more of hydroxypropyl cellulose, sodium polyacrylate, acrylate / C10-30 alkanol acrylate crosspolymer, and acrylate copolymer.

[0018] According to a specific embodiment of the present invention, the composition having skin whitening and brightening function includes one or more of vitamin C ethyl ether, vitamin C glucoside, magnesium vitamin C phosphate, and sodium vitamin C phosphate.

[0019] According to a specific embodiment of the present invention, the composition having skin whitening and brightening function includes one or more of niacinamide, kaempferol, lactic acid, and green tea extract as the melanin transport inhibitor.

[0020] According to a specific embodiment of the present invention, the composition having skin whitening and brightening function includes one or more of soluble collagen, hydrolyzed collagen, yeast lysate extract, and hexapeptide-9.

[0021] The preparation method of the skin whitening and brightening composition of the present invention is as follows:

[0022] Weigh out white truffle extract, black truffle extract, vitamin C derivative, collagen supplement, melanin transport inhibitor and water, mix them, heat to 40-50℃, and stir at 10-15 rpm until completely dissolved.

[0023] Continue stirring at 10-15 rpm, slowly add preservatives and thickeners and stir until evenly mixed. The resulting product is a double truffle extract composition with skin whitening and brightening functions.

[0024] The present invention also provides the application of the above-mentioned composition with whitening and brightening function in the preparation of whitening and brightening cosmetics or skin care products.

[0025] In the aforementioned cosmetics or skincare products, the content of the composition is 5-30%; preferably, the content of the composition is 10-15%.

[0026] The cosmetics or skincare products include toners, lotions, serums, or creams.

[0027] Taking face cream as an example, the ingredients of face cream, by weight, include: 5-30 parts of a composition with whitening and brightening functions, 35-50 parts of water, 0.01-0.02 parts of disodium EDTA, 8-15 parts of glycerin, 0.05-0.2 parts of xanthan gum, 3-8 parts of dipropylene glycol, and glycerin polyether-26. 1-4 parts, hexanediol 0.1-1 part, p-hydroxyacetophenone 0.1-1 part, acrylate / C10-30 alkanol acrylate crosspolymer 0.1-0.8 parts, carbomer 0.1-1 part, olive oil cetyl ester 1-3 parts, cyclopentamethoxysiloxane 0.1-1 part, cyclopentamethoxysiloxane / cyclohexylsiloxane 1-5 parts, polydimethylsiloxane 1-5 parts, isononyl isononanoate 1-5 parts, triethanolamine 0.1-0.8 parts, ethanol 0.1-1 part, and fragrance 0.01-0.1 parts.

[0028] The preparation method for face cream is as follows:

[0029] 1) Weigh out a portion of water, disodium EDTA, glycerin, xanthan gum, dipropylene glycol, glycerin polyether-26, hexanediol and p-hydroxyacetophenone and put them into the main pot, heat to 85°C and stir to mix well;

[0030] 2) Weigh out the whitening and brightening truffle extract composition, the remaining water, acrylate / C10-30 alkanol acrylate crosspolymer, and carbomer, disperse them evenly, and put them into the main pot and stir to mix well.

[0031] 3) Weigh out olive oil cetyl ester, cyclopentamethoxyl, cyclopentamethoxyl / cyclohexylsiloxane, polydimethylsiloxane, and isononyl isononanoate. Heat to 85°C and stir until well mixed. Add to the main pot at 85°C and stir to homogenize for 10 minutes.

[0032] 4) Weigh out triethanolamine and add it to the main pot;

[0033] 5) Once the temperature of the main pot drops below 45℃, weigh out the ethanol and flavoring, add them to the main pot, stir well, and then discharge to obtain the face cream.

[0034] The beneficial effects of this invention are:

[0035] This invention combines five ingredients, including white truffle extract, black truffle extract, soluble collagen, vitamin C ethyl ether, and niacinamide, to comprehensively improve the excessive melanin synthesis, inflammatory response, and collagen degradation caused by UV radiation through multiple pathways, resulting in a composition with skin whitening and brightening functions. Detailed Implementation

[0036] To make the objectives, technical solutions, and advantages of this invention clearer, the technical solutions of this invention will be described in detail below. Obviously, the described embodiments are merely some embodiments of this invention, and not all embodiments. Based on the embodiments of this invention, all other implementation methods obtained by those skilled in the art without creative effort are within the scope of protection of this invention.

[0037] The composition of the present invention having skin whitening and brightening function comprises, by weight: 0.5-20 parts of white truffle extract, 1-20 parts of black truffle extract, 1-10 parts of vitamin C derivative, 5-20 parts of melanin transport inhibitor, and 0.1-10 parts of collagen supplement.

[0038] White truffle extract: purchased from Ashland LLC;

[0039] Black truffle extract: purchased from Draco Natural Products Inc.;

[0040] Vitamin C ethyl ether: Shanghai Jiakai Biotechnology Co., Ltd.;

[0041] Nicotinamide: Hangzhou Weibaolai Biotechnology Co., Ltd.;

[0042] Soluble collagen: Nanjing Novizan Health Technology Co., Ltd.

[0043] Example 1

[0044] Weigh out 5g of white truffle extract, 5g of black truffle extract, 5g of vitamin C ethyl ether, 2g of soluble collagen, 5g of niacinamide and 71g of water, put them into a beaker, heat to 40-50℃, and stir at 10-15 rpm until completely dissolved.

[0045] Continue stirring at 10-15 rpm, slowly add 1.5g of p-hydroxyacetophenone and 0.5g of acrylate / C10-30 alkanol acrylate crosspolymer, stir until homogeneous, and then discharge to obtain a double truffle extract composition with skin whitening and brightening function.

[0046] Example 2

[0047] Weigh 1g of white truffle extract, 5g of black truffle extract, 1g of vitamin C ethyl ether, 8g of soluble collagen, 5g of niacinamide and 78g of water, put them into a beaker, heat to 40-50℃, and stir at 10-15 rpm until completely dissolved.

[0048] Continue stirring at 10-15 rpm, slowly add 1.5g of p-hydroxyacetophenone and 0.5g of acrylate / C10-30 alkanol acrylate crosspolymer, stir until homogeneous, and then discharge to obtain a double truffle extract composition with skin whitening and brightening function.

[0049] Example 3

[0050] Weigh 20g of white truffle extract, 20g of black truffle extract, 0.5g of vitamin C ethyl ether, 1g of soluble collagen, 7.5g of nicotinamide and 49g of water, put them into a beaker, heat to 40-50℃, and stir at 10-15 rpm until completely dissolved.

[0051] Continue stirring at 10-15 rpm, slowly add 1.5g of p-hydroxyacetophenone and 0.5g of acrylate / C10-30 alkanol acrylate crosspolymer, stir until homogeneous, and then discharge to obtain a double truffle extract composition with skin whitening and brightening function.

[0052] Example 4

[0053] Weigh out 5g of white truffle extract, 10g of black truffle extract, 10g of vitamin C ethyl ether, 8g of soluble collagen, 15g of niacinamide and 50g of water, put them into a beaker, heat to 40-50℃, and stir at 10-15 rpm until completely dissolved.

[0054] Continue stirring at 10-15 rpm, slowly add 1.5g of p-hydroxyacetophenone and 0.5g of acrylate / C10-30 alkanol acrylate crosspolymer, stir until homogeneous, and then discharge to obtain a double truffle extract composition with skin whitening and brightening function.

[0055] Comparative Example 1

[0056] Weigh 10g of black truffle extract, 5g of vitamin C ethyl ether, 2g of soluble collagen, 5g of niacinamide and 76g of water, put them into a beaker, heat to 40-50℃, and stir at 10-15 rpm until completely dissolved.

[0057] Continue stirring at 10-15 rpm, slowly add 1.5g of p-hydroxyacetophenone and 0.5g of acrylate / C10-30 alkanol acrylate crosspolymer, stir until homogeneous, and then discharge to obtain a double truffle extract composition with skin whitening and brightening function.

[0058] Comparative Example 2

[0059] Weigh 10g of white truffle extract, 5g of vitamin C ethyl ether, 2g of soluble collagen, 5g of niacinamide and 76g of water, put them into a beaker, heat to 40-50℃, and stir at 10-15 rpm until completely dissolved.

[0060] Continue stirring at 10-15 rpm, slowly add 1.5g of p-hydroxyacetophenone and 0.5g of acrylate / C10-30 alkanol acrylate crosspolymer, stir until homogeneous, and then discharge to obtain a double truffle extract composition with skin whitening and brightening function.

[0061] Comparative Example 3

[0062] Weigh 10g of white truffle extract, 10g of black truffle extract, 2g of soluble collagen, 5g of niacinamide and 71g of water, put them into a beaker, heat to 40-50℃, and stir at 10-15 rpm until completely dissolved.

[0063] Continue stirring at 10-15 rpm, slowly add 1.5g of p-hydroxyacetophenone and 0.5g of acrylate / C10-30 alkanol acrylate crosspolymer, stir until homogeneous, and then discharge to obtain a double truffle extract composition with skin whitening and brightening function.

[0064] Comparative Example 4

[0065] Weigh 10g of white truffle extract, 10g of black truffle extract, 5g of vitamin C ethyl ether, 5g of nicotinamide and 68g of water, put them into a beaker, heat to 40-50℃, and stir at 10-15 rpm until completely dissolved.

[0066] Continue stirring at 10-15 rpm, slowly add 1.5g of p-hydroxyacetophenone and 0.5g of acrylate / C10-30 alkanol acrylate crosspolymer, stir until homogeneous, and then discharge to obtain a double truffle extract composition with skin whitening and brightening function.

[0067] Comparative Example 5

[0068] Weigh 10g of white truffle extract, 10g of black truffle extract, 5g of vitamin ethyl ether, 2g of soluble collagen and 71g of water, put them into a beaker, heat to 40-50℃, and stir at 10-15 rpm until completely dissolved.

[0069] Continue stirring at 10-15 rpm, slowly add 1.5g of p-hydroxyacetophenone and 0.5g of acrylate / C10-30 alkanol acrylate crosspolymer, stir until homogeneous, and then discharge to obtain a double truffle extract composition with skin whitening and brightening function.

[0070] Example 1: Performance Testing

[0071] The general storage stability of the double truffle extract composition with skin whitening and brightening functions was evaluated according to GB / T29665-2013. The results of the general storage stability test for Examples 1-4 are shown in Table 1.

[0072] Table 1. Results of general storage stability tests for Examples 1-4

[0073]

[0074] As shown in Table 1, the compositions of Examples 1-4 of the present invention all meet the requirements.

[0075] Test Example 2: Whitening and Brightening Efficacy Test (Composition)

[0076] Using a human 3D melanin skin model as a test tool, the whitening and brightening skin-enhancing compositions of double truffle extract prepared in Examples 1-4 and Comparative Examples 1-5 were applied to the surface of the human 3D melanin skin model by surface drug delivery. The in vitro whitening and brightening effects of each sample were evaluated by detecting changes in the melanin content of the model.

[0077] The human 3D melanin skin model (batch number: MS210401, Guangdong Boxi Biotechnology Co., Ltd.) on Day 0 of the manufacturing date was transferred to a 6-well plate containing 3.3 mL of MC-TA culture medium (Guangdong Boxi Biotechnology Co., Ltd.) and cultured in an incubator at 37°C, 5% CO2 and 95% relative humidity.

[0078] The human 3D melanin skin model has its culture medium changed daily and is irradiated with UVB (50 mJ / cm²). 2 Stimulation treatment was administered, and drug administration began on Day 3 after three consecutive days of stimulation.

[0079] A model without UVB irradiation was used as a blank control; a model with only irradiation but no drug administration was used as a negative control.

[0080] Kojic acid at a concentration of 42.67 μg / mL was used as a positive control. It was added to the culture medium and mixed well. The culture medium was changed and the drug was administered daily. Stimulation was continued for 4 days (Day 3 to Day 6) and then ended. Melanin content was detected on Day 7. The sample groups (Examples 1-4, Comparative Examples 1-5) were evenly coated on the model surface. The drug administration volume was 10 μL. The drug was administered once every 2 days. Stimulation was continued for 4 days (Day 3 to Day 6) and then ended.

[0081] Melanin content was measured in the blank group and negative control group on Day 0, Day 3 and Day 7, respectively, while melanin content was measured in the positive control and sample group on Day 7.

[0082] The detection method is as follows: The test model was treated with 0.6 mL of 0.25% trypsin, incubated at 37℃ for 2 hours, followed by repeated pipetting for about 1 minute. After removing the detached PC membrane, 0.6 mL of PBS containing 10% serum was added, and the mixture was centrifuged at 2000 rpm for 10 minutes, discarding the supernatant. The precipitate was then treated with 1 mol / L NaOH containing 10% DMSO, pipetted several times, and incubated in an 80℃ water bath for 30 minutes to completely dissolve the melanin granules. The mixture was then centrifuged at 1200 rpm for 5 minutes, and the supernatant was added to a 96-well plate (200 μL per well, 2 replicates per model). The absorbance was measured at 405 nm, and a standard curve was plotted based on the absorbance values ​​of the melanin standard. The melanin content of each model was calculated. Samples with significantly lower melanin content than the negative control group showed a whitening effect. GraphPadPrism Program software was used for plotting, and t-tests were used for statistical analysis of each component. p < 0.05 indicated a significant difference.

[0083] Melanin content was detected in a human 3D melanin skin model, and the results are shown in Table 2.

[0084] Table 2 Summary of Melanin Content Detection Results for 3D Melanin Skin Models (7 days)

[0085]

[0086] Note: Significance compared to the negative control group is indicated by *; significance compared to Example 1 is indicated by #.

[0087] The results of the melanin content test showed that, compared with the blank control group, the melanin content of the negative control group was significantly increased (p<0.05); compared with the negative control group, the melanin content of the positive control group was significantly decreased (p<0.05), indicating that the experimental conditions were effective.

[0088] Compared with the negative control group, the melanin content of the melanin models treated in Examples 1-4 and Comparative Examples 3-5 was significantly reduced, while the melanin content of the melanin model treated in Comparative Examples 1-2 was reduced, but not significantly. This indicates that Examples 1-4 and Comparative Examples 3-5 can inhibit melanin production. Furthermore, compared with Example 1, the decrease in melanin content in the melanin models treated in Comparative Examples 1-5 was significantly different, indicating that the effect of Comparative Examples 1-5 on reducing melanin content in the melanin models was weaker than that of Example 1.

[0089] Compared to the skin-brightening and whitening truffle extract composition prepared in Example 1, Comparative Example 1 did not contain white truffle extract, Comparative Example 2 did not contain black truffle extract, Comparative Example 3 did not contain vitamin C ethyl ether, Comparative Example 4 did not contain soluble collagen, and Comparative Example 5 did not contain niacinamide. Therefore, it is demonstrated that the composition of white truffle extract, black truffle extract, vitamin C ethyl ether, soluble collagen, and niacinamide is the most effective in brightening skin tone.

[0090] Test Example 3: Whitening and Brightening Efficacy Test (Formula Application Example)

[0091] To better illustrate the applicability of the present invention, the double truffle extract composition with whitening and brightening function prepared in Example 1 of the present invention was added to a face cream at an addition amount of 30%, and the stability, safety and brightening effect of the face cream were examined.

[0092] The preparation method for face cream is as follows:

[0093] 1) Weigh 520.5g water, 1g disodium EDTA, 516.5g glycerin, 5g xanthan gum, 258g dipropylene glycol, 129g glycerin polyether-26, 25g hexanediol and 25g p-hydroxyacetophenone into the main pot, heat to 85℃ and stir until well mixed.

[0094] 2) Weigh 1500g of the double truffle extract composition with whitening and brightening function prepared in Example 1, 1500g of water, 20g of acrylate / C10-30 alkanol acrylate crosspolymer, and 10g of carbomer, disperse them evenly, and put them into the main pot and stir to mix evenly.

[0095] 3) Weigh 75g of olive oil cetyl ester, 25g of cyclopentamethoxysiloxane, 100g of cyclopentamethoxysiloxane / cyclohexylsiloxane, 150g of polydimethylsiloxane, and 100g of isononyl isononanoate. Heat to 85℃ and stir until well mixed. Add to the main pot at 85℃ and stir to homogenize for 10 minutes.

[0096] 4) Weigh 15g of triethanolamine and add it to the main pot;

[0097] 5) Once the temperature of the main pot drops below 45℃, weigh out 20g of ethanol and 5g of flavoring and add them to the main pot. Stir well and then discharge the product to obtain the face cream.

[0098] The preservative efficacy test adopts the international standard ISO 11930:2012 (cosmetics—microbiology—assessment of antimicrobial protection of cosmetic products).

[0099] The results of the preservative efficacy test for the face cream are shown in Table 3:

[0100] Table 3 Results of Anti-corrosion Efficacy Test

[0101]

[0102]

[0103] The results showed that the face cream met the standard A in Table B.1 of Annex B of ISO 11930-2012.

[0104] Safety testing is conducted in accordance with the requirements of the "Cosmetic Safety Technical Specifications" using appropriate technical means to detect the safety of heavy metals (lead, mercury, arsenic, cadmium), hazardous substances (diethylene glycol, dioxane), and microorganisms in face creams.

[0105] Table 4. Results of Heavy Metal and Hazardous Substance Detection in Face Cream

[0106]

[0107] Table 5. Microbial Detection Results of Face Cream

[0108]

[0109] The results are shown in Tables 4 and 5. Lead, mercury, arsenic and cadmium were not detected in the face cream prepared by this invention, and the microbial indicators met the standards.

[0110] Skin whitening and brightening efficacy test

[0111] We are recruiting 33 female volunteers (aged 20 to 60) to participate in a test of the skin-brightening and whitening effects of a face cream. The test will last for 4 weeks.

[0112] During the test, volunteers used the face cream twice daily, morning and evening, for four consecutive weeks. During the test, the use of other cosmetics claiming moisturizing, whitening, brightening, or similar effects was prohibited. Skin moisture content and skin color were tested on one randomized cheek before face cream application (initial values), and at two and four weeks after application. Skin moisture content was measured using the probe of a Cornemeter (CM825, Courage and Khazaka, Germany), and skin color was measured using a Chromameter (CR-400, Konica Minolta, Japan).

[0113] All 33 volunteers completed the entire test, and no adverse reactions occurred during the test. Skin moisture content and color were tested on one cheek at random before cream application (initial values), and 2 and 4 weeks after cream application. The results are shown in Table 6.

[0114] Table 6. Statistical results of skin moisture and color before and after using face cream.

[0115]

[0116] A higher skin moisture content indicates higher skin hydration. The results, shown in Table 6, indicate that compared to the initial values, the skin moisture content in the test areas significantly improved after 2 and 4 weeks of cream use. This demonstrates that using the cream for 2 or 4 weeks can significantly improve skin hydration and provides a certain moisturizing effect.

[0117] The L* value represents brightness; a higher value indicates whiter and brighter skin. The a value represents red-green hue; a higher value indicates redder skin. The b value represents blue-yellow hue; a higher value indicates yellower skin. ITA° is the individual type angle; a larger angle indicates lighter skin. Compared to initial values, after 2 and 4 weeks of cream use, the L* and ITA° values ​​of the volunteers' skin test areas significantly increased. This demonstrates that the use of the cream can significantly improve skin brightness.

[0118] The above description is merely a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in the present invention should be included within the scope of protection of the present invention. Therefore, the scope of protection of the present invention should be determined by the scope of the claims.

Claims

1. A composition having skin-whitening and brightening functions, characterized in that, By weight, it consists of the following components: 0.5-20 parts white truffle extract, 1-20 parts black truffle extract, 1-10 parts vitamin C ethyl ether, 5-20 parts nicotinamide, and 0.1-10 parts soluble collagen.

2. The composition with skin whitening and brightening function according to claim 1, characterized in that, It also includes 1-1.5 parts of preservative and 0.15-1.5 parts of thickener.

3. The composition with skin whitening and brightening function according to claim 2, characterized in that, The preservatives include one or more of p-hydroxyacetophenone, 1,2-pentanediol, 1,2-hexanediol, octyl glycol, raspberry ketone, and phenoxyethanol.

4. The composition with skin whitening and brightening function according to claim 2, characterized in that, The thickener includes one or more of hydroxypropyl cellulose, sodium polyacrylate, acrylate / C10-30 alkanol acrylate crosspolymers, and acrylate copolymers.

5. The use of the composition with skin whitening and brightening function according to any one of claims 1-4 in the preparation of skin whitening and brightening cosmetics.

6. The application according to claim 5, characterized in that, The cosmetic product contains 5-30% of the composition; the cosmetic product includes toner, lotion, serum or cream.

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