Composition containing oligofructose and probiotics and application thereof

The combination of oligofructose and Bifidobacterium longum infantis subspecies GB-1496, Bifidobacterium animalis BB12 and/or Bifidobacterium lactis HN019 solves the problem of insufficient proliferation of Bifidobacterium longum infantis subspecies GB-1496 in the intestine and improves its antioxidant and immunomodulatory effects.

CN116998725BActive Publication Date: 2025-09-16INNER MONGOLIA YILI IND GROUP CO LTD
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Patent Information

Application Number
CN202311012147.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2020-11-30
Publication Date
2025-09-16
Estimated Expiration
2040-11-30

AI Technical Summary

Technical Problem

In the prior art, Bifidobacterium longum subspecies infantis GB-1496 has a poor proliferation effect in the human intestine, making it difficult to fully exert its antioxidant and immunomodulatory functions.

Method used

Provided is a composition containing oligofructose and probiotics. The probiotics are composed of Bifidobacterium longum subspecies infantis GB-1496, Bifidobacterium animalis BB12 and/or Bifidobacterium lactis HN019. The probiotics are mixed in a specific proportion to promote the proliferation of Bifidobacterium longum subspecies infantis GB-1496 in the intestine.

Benefits of technology

It enhances the proliferation of Bifidobacterium longum subspecies infantis GB-1496 in the intestine, improves its antioxidant activity and immunomodulatory function, and promotes intestinal health.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention provides a composition containing oligofructose and probiotics and its application. The probiotics in the composition containing oligofructose and probiotics of the present invention are animal Bifidobacterium BB12, Bifidobacterium lactis HN019 and Bifidobacterium longum infantis subspecies GB-1496. The present invention also provides the application of the above composition in promoting the proliferation of Bifidobacterium longum infantis subspecies GB-1496. The present invention has found that using FOS as a carbon source and compounding Bifidobacterium animalis BB12, Bifidobacterium lactis HN019 and Bifidobacterium longum infantis subspecies GB-1496 can significantly promote the proliferation of Bifidobacterium infantis, and the number of proliferation is significantly higher than the single combination of FOS and animal Bifidobacterium BB12, Bifidobacterium lactis HN019 and Bifidobacterium longum infantis subspecies GB-1496.
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Claims

1. A composition containing oligofructose and probiotics, wherein: The probiotics are composed of Bifidobacterium longum subspecies infantis GB-1496, Bifidobacterium animalis BB12 and Bifidobacterium lactis HN019; The ratio of oligofructose: Bifidobacterium animalis BB12 and Bifidobacterium lactis HN019: Bifidobacterium longum infantis GB-1496 is 1g:(10 6 -10 13 )cfu:(10 6 -10 13 )cfu.

2. The composition according to claim 1, wherein The content of the oligofructose is 0.1-20g.

3. A nutritional composition comprising the composition according to claim 1 or 2. A food comprising the composition according to claim 1 or 2 and / or the nutritional composition according to claim 3.

5. The food according to claim 4, wherein The food is food for children or food for the elderly.

6. The food according to claim 4, wherein The food includes one or a combination of two or more of milk powder, complementary food, and beverages.

7. A medicine comprising the composition according to claim 1 or 2 and / or the nutritional composition according to claim 3.

8. Use of a combination of fructooligosaccharides, Bifidobacterium animalis BB12, Bifidobacterium lactis HN019, and Bifidobacterium longum subsp. infantis GB-1496 in promoting the proliferation of Bifidobacterium longum subsp. infantis GB-1496; in, The ratio of oligofructose: Bifidobacterium animalis BB12 and Bifidobacterium lactis HN019: Bifidobacterium longum infantis GB-1496 is 1g:(10 6 -10 13 )cfu:(10 6 -10 13 )cfu.

9. Use of the composition containing oligofructose and probiotics according to claim 1 or 2 in promoting the proliferation of Bifidobacterium longum subspecies infantis GB-1496.

10. The use according to claim 8 or 9, wherein: The promotion refers to promoting the proliferation of Bifidobacterium longum subspecies infantis GB-1496 in the intestine.

Citation Information

Patent Citations

  • Five-probiotic nutritive powder and preparation method thereof

    CN107212415A