Pathogen Nucleic Acid Aerosol Purification Device

Abstract

A kind of pathogen nucleic acid aerosol purification device, including shell, shell includes frame, frame is equipped with front panel (2), left side plate (3), right side plate (4), back baffle (5) and top cover (6), the front panel (2) is an arc-shaped plate, the front panel (2) is gradually bent from bottom to top, the back baffle (5) and the top cover (6) are rectangle, the back baffle (5) is located in left-right vertical direction, and the top cover (6) is located in horizontal direction.The purpose is to provide a kind of biological laboratory air can be no dead angle sufficient circulation, when air circulation, as far as possible no vortex, no cross disturbance, to the nucleic acid fragment, virus and bacterial microorganism existing in aerosol in biological laboratory air complete high-efficiency disinfection, removal in very short time, to the suspended particulate matter existing in biological laboratory air complete high-efficiency removal pathogen nucleic acid aerosol purification device.

Description

Technical Field

[0001] This invention relates to a pathogen nucleic acid aerosol purification device. Background Technology

[0002] Aerosol nucleic acid fragments are generated during the shaking and centrifugation of nucleic acid samples in biological testing experiments. These fragments readily diffuse into the air after the sample is opened, and even minute amounts can contaminate the entire laboratory. Aerosol nucleic acid fragment contamination is a common problem in laboratories, and addressing this issue is an urgent problem that needs to be solved in biological testing experiments, a challenge faced by the biological field both domestically and internationally.

[0003] Currently, all general hospitals at level two or above in China have nucleic acid testing capabilities in their biochemical laboratories, and most hospitals have also established PCR laboratories. PCR laboratories are also called gene amplification laboratories. PCR is short for Polymerase Chain Reaction. It is a molecular biology technique used to amplify specific DNA fragments, and can be viewed as a special form of DNA replication outside of a living organism.

[0004] As key units for infectious disease prevention and control and biohazard defense, biological laboratories rely on clean experimental spaces and complete experimental conditions for early detection, warning, testing and defense, and to solve the problem of aerosol nucleic acid fragment contamination. Summary of the Invention

[0005] The purpose of this invention is to provide a pathogen nucleic acid aerosol purification device that allows for complete air circulation without dead zones in a biological laboratory, ensuring minimal eddies and cross-disturbance during air circulation, and efficiently disinfecting and removing nucleic acid fragments, viruses, and bacterial microorganisms present in aerosols in the air of a biological laboratory in a very short time, and efficiently removing suspended particulate matter present in the air of a biological laboratory.

[0006] The pathogen nucleic acid aerosol purification device of the present invention includes a housing, the housing includes a frame, and the frame is provided with a front panel, a left side panel, a right side panel, a rear baffle and a top cover. The front panel is an arc-shaped panel that gradually bends forward from bottom to top. The rear baffle and the top cover are rectangular. The surface of the rear baffle is located in the left and right vertical direction, and the surface of the top cover is located in the horizontal direction.

[0007] The bottom of the casing is the air inlet. The front panel, left side panel, right side panel, rear baffle and top cover form an air duct that allows air to flow from bottom to top. Multiple centrifugal fans are arranged side by side at intervals along the horizontal direction in the upper part of the air duct. The air inlet of each centrifugal fan is located in the air duct. The air outlet of each centrifugal fan is connected to the air inlet of the arc-shaped jet pipe. The arc-shaped jet pipe is arranged along the front and back direction. The cross section of the arc-shaped jet pipe along the vertical direction is rectangular. The air outlet end of each arc-shaped jet pipe is fixedly connected to the upper part of the front panel. Each arc-shaped jet pipe is a curved arc with a lower air inlet end and a higher air outlet end.

[0008] An ozone removal filter is installed horizontally below the centrifugal fan in the air duct. Below the ozone removal filter, a microporous filter membrane made of H14 grade high-efficiency filter material is installed horizontally in the air duct. Below the microporous filter membrane, an air electrostatic disinfection and purification module is installed horizontally in the air duct. A coarse filter is installed at the air inlet at the bottom of the casing.

[0009] The pathogen nucleic acid aerosol purification device of the present invention, wherein the bottom or side of the front panel is connected to the frame by a hinge, the upper part of the front panel is connected to the frame, the left side panel or the right side panel by screws or door latches, and an airtight strip is provided at the edge of the front panel.

[0010] The pathogen nucleic acid aerosol purification device of the present invention includes 3-5 centrifugal fans, which are adjustable air volume fans. The height of the casing in the vertical direction is 1500mm-1700mm, the width of the casing in the horizontal direction is 1400mm-1900mm, the width of the top of the casing in the front-back direction is 600mm-800mm, and the width of the bottom of the casing in the front-back direction is 300mm-500mm.

[0011] The pathogen nucleic acid aerosol purification device of the present invention has a plurality of ultraviolet lamps for sterilization on the front-facing surface of the rear baffle.

[0012] The pathogen nucleic acid aerosol purification device of the present invention includes an air electrostatic disinfection and purification module comprising multiple foam metal plates whose surfaces can be traversed by airflow. The surfaces of the foam metal plates are arranged vertically along the front and back direction, and airflow channels are provided between the foam metal plates. A discharge electrode is provided in the middle of the airflow channel along the front and back horizontal direction. The multiple foam metal plates and the discharge electrode are respectively installed on the air electrostatic disinfection and purification module frame, and the air electrostatic disinfection and purification module frame is inserted into the air duct with a gap fit.

[0013] The pathogen nucleic acid aerosol purification device of the present invention, wherein the thickness of the foam metal plate is 5mm-15mm.

[0014] The pathogen nucleic acid aerosol purification device of the present invention wherein the foam metal plate has a pore size (PPI) of 80-120 per inch, a porosity of 98%, and a bulk density of 0.1 g / cm³. 3 The porosity is no more than 98%.

[0015] The pathogen nucleic acid aerosol purification device of the present invention has a coarse filter at the air inlet at the bottom of the casing to remove various larger coarse impurities. Then, the airflow enters the air electrostatic disinfection and purification module, where it passes through a high-voltage electric field to disinfect and capture microorganisms. Then, a microporous filter membrane made of H14 grade high-efficiency filter material is used to further capture any remaining nucleic acid fragments of the disinfected microorganisms to ensure the final purification effect. An ozone removal filter is used to remove ozone from the airflow. The present invention also features multiple centrifugal fans arranged side by side at horizontal intervals in the upper part of the air duct, with the air inlet of each centrifugal fan located inside the air duct. Each centrifugal fan's outlet is connected to the inlet of an arc-shaped jet pipe. The arc-shaped jet pipe is arranged along the front-to-back direction, and its cross-section along the left-to-right vertical direction is rectangular. The outlet end of each arc-shaped jet pipe is fixedly connected to the upper part of the front panel. Each arc-shaped jet pipe is a curved shape with a lower inlet end and a higher outlet end. Because the arc-shaped jet pipe at the outlet is designed as an arc, and the front panel is an arc-shaped plate that gradually bends forward from bottom to top, this design can generate a better fluid adhesion effect and can drive the air around the front panel to flow with the air ejected from the outlet, enhancing the airflow in the entire biological laboratory and avoiding dead corners. Therefore, the pathogen nucleic acid aerosol purification device of the present invention has the characteristics of enabling full circulation of air in the biological laboratory without dead corners, ensuring that the air circulation is as free of eddies and cross disturbances as possible, and efficiently disinfecting and removing nucleic acid fragments, viruses and bacteria present in aerosols in the air of the biological laboratory in a very short time, and efficiently removing suspended particulate matter present in the air of the biological laboratory.

[0016] The pathogen nucleic acid aerosol purification device of the present invention will be further described in detail below with reference to the accompanying drawings. Attached Figure Description

[0017] Figure 1 This is a front view of a schematic diagram of the pathogen nucleic acid aerosol purification device of the present invention.

[0018] Figure 2 for Figure 1 Side view sectional view;

[0019] Figure 3 for Figure 1 Top view;

[0020] Figure 4This is an enlarged front view of the foam metal plate portion in the air electrostatic disinfection and purification module of the pathogen nucleic acid aerosol purification device of the present invention.

[0021] Figure 5 This is a front view of the pathogen nucleic acid aerosol purification device of the present invention after it has been installed in a biological laboratory.

[0022] Figure 6 for Figure 5 Top view. Detailed Implementation

[0023] like Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 and Figure 6 As shown, the pathogen nucleic acid aerosol purification device of the present invention includes a housing, the housing includes a frame, and the frame is provided with a front panel 2, a left side panel 3, a right side panel 4, a rear baffle 5 and a top cover 6. The front panel 2 is an arc-shaped panel that gradually bends forward from bottom to top. The rear baffle 5 and the top cover 6 are rectangular. The surface of the rear baffle 5 is located in the left and right vertical direction, and the surface of the top cover 6 is located in the horizontal direction.

[0024] The bottom of the casing is the air inlet. The front panel 2, left side panel 3, right side panel 4, rear baffle 5 and top cover 6 form an air duct 7 that allows air to flow from bottom to top. Multiple centrifugal fans 10 are arranged side by side at intervals along the left and right horizontal direction in the upper part of the air duct 7. The air inlet of each centrifugal fan 10 is located in the air duct 7. The air outlet of each centrifugal fan 10 is connected to the air inlet of the arc-shaped jet pipe 15. The arc-shaped jet pipe 15 is arranged along the front and back direction. The cross section of the arc-shaped jet pipe 15 along the left and right vertical direction is rectangular. The air outlet end of each arc-shaped jet pipe 15 is fixedly connected to the upper part of the front panel 2. Each arc-shaped jet pipe 15 is a curved arc with a lower air inlet end and a higher air outlet end.

[0025] An ozone deodorization filter 11 is installed horizontally below the centrifugal fan 10 in the air duct 7. A microporous filter membrane 12 made of H14 grade high-efficiency filter material is installed horizontally below the ozone deodorization filter 11 in the air duct 7. An air electrostatic disinfection and purification module 13 is installed horizontally below the microporous filter membrane 12 in the air duct 7. A coarse filter 14 is installed at the air inlet at the bottom of the housing.

[0026] In use, a pathogen nucleic acid aerosol purification device 1 can be suspended and fixed on the upper part of a wall inside the biological laboratory 20. The rear baffle 5 of the pathogen nucleic acid aerosol purification device 1 is attached to the corresponding wall. The air inlet of the pathogen nucleic acid aerosol purification device 1 is arranged facing the ground inside the biological laboratory 20. The top cover 6 of the pathogen nucleic acid aerosol purification device 1 is attached to the roof inside the biological laboratory 20 or located near the roof inside the biological laboratory 20.

[0027] Furthermore, a pathogen nucleic acid aerosol purification device 1 can be installed on the lower part of another wall opposite to the wall where a pathogen nucleic acid aerosol purification device 1 is fixed in the biological laboratory 20. The rear baffle 5 of the pathogen nucleic acid aerosol purification device 1 is attached to the corresponding wall. The air inlet of the pathogen nucleic acid aerosol purification device 1 is arranged facing the roof inside the biological laboratory 20. The top cover 6 of the pathogen nucleic acid aerosol purification device 1 is attached to or located near the ground inside the biological laboratory 20.

[0028] As a further improvement of the present invention, the bottom or side of the front panel 2 is connected to the frame by a hinge, the upper part of the front panel 2 is connected to the frame, the left side panel 3 or the right side panel 4 by screws or door latches, and an airtight strip is provided at the edge of the front panel 2.

[0029] As a further improvement of the present invention, a pathogen nucleic acid aerosol purification device 1 is suspended and fixed on the upper part of the west side of the north wall inside the above-mentioned biological laboratory 20, and a pathogen nucleic acid aerosol purification device 1 is fixed on the lower part of the east side of the south wall inside the biological laboratory 20.

[0030] As a further improvement of the present invention, the number of centrifugal fans 10 is 3-5, the centrifugal fans 10 are adjustable air volume fans, the height of the casing along the vertical direction is 1500mm-1700mm, the width of the casing along the horizontal direction is 1400mm-1900mm, the width of the top of the casing along the front-back direction is 600mm-800mm, and the width of the bottom of the casing along the front-back direction is 300mm-500mm.

[0031] As a further improvement of the present invention, the height from the ground to the roof in the above-mentioned biological laboratory 20 is 2500mm-2700mm, and the ground area in the biological laboratory 20 is 30-50 square meters.

[0032] As a further improvement of the present invention, the front-facing surface of the rear baffle 5 is provided with a plurality of ultraviolet lamps for sterilization.

[0033] As a further improvement of the present invention, the above-mentioned air electrostatic disinfection and purification module 13 includes multiple foam metal plates 16 whose surfaces can be traversed by airflow. The surfaces of the foam metal plates 16 are arranged along the front-to-back vertical direction, and airflow channels 17 are provided between the foam metal plates 16. A discharge electrode 18 is provided in the middle of the airflow channel 17 along the front-to-back horizontal direction. The multiple foam metal plates 16 and the discharge electrode 18 are respectively installed on the air electrostatic disinfection and purification module frame, and the air electrostatic disinfection and purification module frame is inserted into the air duct 7 with a gap fit.

[0034] Compared to the ordinary anode plates used in traditional electrostatic precipitators, where the electric field is only distributed on the surface, the porous structure of the foam metal plate 16 is three-dimensionally distributed, thus creating a three-dimensional electric field. Furthermore, its spike-like shape alters the spatial electric field, transforming it into a field similar to that formed by sharp points, increasing the local electric field strength and enhancing the breaking effect of nucleic acid bonds. Simultaneously, compared to ordinary anode plates, the foam metal plate 16 has a much larger dust collection area for the same volume, equivalent to 50 times that of ordinary anode plates, significantly improving the efficiency of capturing nucleic acid fragments, viruses, and bacterial microorganisms present in the air of the biological laboratory 20.

[0035] As a further improvement of the present invention, the thickness of the foam metal plate 16 is 5mm-15mm.

[0036] As a further improvement of the present invention, the number of holes per inch (PPI) of the above-mentioned foam metal plate 16 is 80-120, the porosity is 98%, the bulk density of the foam metal plate 16 is 0.1 g / cm3, and the open porosity is not greater than 98%.

[0037] The design of the pathogen nucleic acid aerosol purification device of the present invention referenced the following national standards:

[0038] JGJ91-93 Code for Design of Scientific Laboratory Buildings

[0039] GB 50346-2011 Technical Specification for Biosafety Laboratory Construction

[0040] GB / 19489-2008 General Requirements for Laboratory Biosafety

[0041] GB 14925-2010 Laboratory Animal Environment and Facilities

[0042] GB / T29475-2012 "Design Principles and Basic Requirements for Mobile Laboratories"

[0043] GB / T29479-2012 General Requirements for Mobile Laboratories

[0044] National Standard for Laboratory Animal Environment and Facilities (GB 14925-2010)

[0045] According to the relevant design specifications for ventilation in safety laboratories, the air circulation volume for disinfection and purification in Biological Laboratory 20 must meet the requirement of at least 15 disinfection and purification cycles per hour. If the preset conditions for Biological Laboratory 20 are: a usable area of ​​40 square meters, a room height of 2.6 meters, and an indoor air volume of 104 cubic meters, then the minimum total air circulation volume for disinfection and purification in Biological Laboratory 20 is: 104 * 15 = 1560 m³. 3 / h.

[0046] During the design process of the pathogen nucleic acid aerosol purification device of this invention, after multiple comprehensive comparisons of various unit placement methods and different equipment air outlet designs, it was found that the best air circulation effect was achieved when two units were placed opposite each other in Room 20 of the biological laboratory, with the air inlet and outlet of the two units designed in opposite directions and symmetrically. This can minimize the problems of severe imbalance in circulation and numerous dead zones in Room 20 of the biological laboratory caused by traditional top-supply and top-return air fields and floor-standing air sterilizers.

[0047] The fan of the two pathogen nucleic acid aerosol purification device 1 can be designed to be 1000m. 3 / h and 600m 3 Two airflow rates are available: 1000 m³ / h. In a biological laboratory where no one is present and disinfection is required, the 1000 m³ / h rate can be used. 3 The 600 m³ / h airflow mode maximizes the number of indoor air circulations; when people and machines coexist, the 600 m³ / h airflow mode is used to keep the air in the biological laboratory 20 in a relatively stable state while disinfecting and purifying. The air purification circulation times for the 40 square meter, 2.6-meter-high biological laboratory 20 room are 19 and 12 respectively under the two airflow modes.

[0048] The air electrostatic disinfection and purification module 13 and coarse filter 14 of the pathogen nucleic acid aerosol purification device 1 can be manually cleaned, and the microporous filter membrane 12 made of H14 grade high-efficiency filter material can be replaced periodically according to the usage time.

[0049] In summary, the diagonal arrangement of the inlet and outlet of the two pathogen nucleic acid aerosol purification devices 1 ensures that the airflow effectively fills the entire biological laboratory 20 without forming eddies. This guarantees that all airflow within the biological laboratory 20 can smoothly enter the inlet of the pathogen nucleic acid aerosol purification device 1, and that the airflow of a single pathogen nucleic acid aerosol purification device 1 is 1000 m³ / h. 3 Under operating conditions of / h, more than 97% of the airflow velocity in the biological laboratory is greater than 0.05m / s.

[0050] The microbial inactivation principle of the air electrostatic disinfection and purification module 13 of the present invention is as follows.

[0051] The air electrostatic disinfection and purification module 13 of the present invention inactivates microorganisms mainly through the following two aspects:

[0052] (1) The air electrostatic disinfection and purification module 13 can continuously release plasma. The inactivating components (active groups, charged particles and electric fields, etc.) in the plasma cause microorganisms to die rapidly through biological damage (cell membrane damage, biological macromolecule damage and microbial sublethality).

[0053] (2) The air electrostatic disinfection and purification module 13 can continuously release electric field force through a strong electric field of 30,000 volts to produce a polarization effect on microorganisms and nucleic acids. The active tissues of microorganisms are instantly broken by the strong electric field, which inactivates them and affects the nucleic acid sequence order, further preventing the possibility of microbial amplification and replication.

[0054] (3) Killing microorganisms through plasma: The air electrostatic disinfection and purification module 13 can release a large amount of plasma through a high-voltage electric field. Plasma is a conductive fluid that is electrically neutral and composed of electrons, ions, free radicals, excited-state particles, etc. Its composition is complex and diverse, and its properties are active. In addition to high-energy particles, ultraviolet rays and high-energy electric fields, there are many active particles that are excited or unexcited. When these active particles come into contact with microorganisms, a series of complex biochemical reactions and physical processes will occur between them and the biofilm.

[0055] From a macroscopic perspective, the sterilization process of atmospheric pressure low-temperature plasma is actually the interaction between the active components generated by the plasma (such as positive and negative ions, active groups, charged particles and electric fields, ultraviolet light, etc.) and biological macromolecules (such as proteins, DNA, lipids, etc.), causing changes in cellular components (such as cell walls, cell membranes, cytoplasm, etc.), and ultimately leading to cell death. The active components of the plasma either inactivate and denature biological macromolecules in a short period of time, or alter the level of oxidative stress within the cell, thereby achieving the purpose of microbial inactivation.

[0056] The main microbial inactivation components of plasma

[0057] In the sterilization process of atmospheric pressure low-temperature plasma, active groups, charged particles, and electric fields are the main factors of concern.

[0058] 1) Active groups

[0059] The current mainstream theory on the sterilization mechanism of atmospheric pressure low-temperature plasma believes that reactive oxygen species (ROS) and reactive nitrogen species (RNS) play the main roles in inducing cell death. Table 1 shows the common ROS and RNS in plasma.

[0060] Table 1 Common ROS / RNS in Plasma

[0061]

[0062] 2) Charged particles and electric fields

[0063] During plasma generation, an electric field exists between two high-voltage electrodes, and the working gas dissociates between the electrodes, forming numerous charged particles. Related studies have shown that when bacterial samples are placed in a dielectric barrier discharge gap, the plasma transfers charged matter to the bacterial surface, while the high electric field intensity also has a certain impact on the bacteria. Plasma can disrupt the external structure of microorganisms, causing leakage of proteins, nucleic acids, and K+ from the cytoplasm, with charged particles and active substances playing a major role.

[0064] Biological damage of plasma to microorganisms: When plasma acts on microorganisms, different tissues of the microorganisms will produce different biological responses. The biological response mechanism of cells can be summarized into the following three points:

[0065] 1) Cell membrane damage theory

[0066] When the active substances generated by plasma act on the cell membrane, lipids on the cell membrane undergo peroxidation, and the cell membrane potential changes. This increases cell membrane permeability, causing more plasma active components from the outside to enter the cell, resulting in leakage of cell contents. At this point, the cell membrane collapses or becomes defective, disrupting normal physiological functions and causing the cell membrane to rupture, leading to apoptosis or even cell death.

[0067] 2) The theory of damage by biological macromolecules

[0068] When the active components of the plasma act on cells, they cause oxidative damage to biological macromolecules such as proteins, nucleic acids, and lipids, leading to complex biochemical reactions such as protein denaturation, DNA oxidative degradation, and lipid peroxidation, which in turn have a significant impact on the physiological functions of biological tissues.

[0069] 3) Microbial sublethal theory

[0070] Microorganisms treated with plasma did not show obvious morphological damage, but their metabolic capacity was weakened, their growth was slowed or stopped, and the activity of metabolic enzymes was destroyed, ultimately leading to microbial death. Among these factors, plasma-induced cellular lipid peroxidation may be the main factor causing the cells to be in a sublethal state.

[0071] The pathogen nucleic acid aerosol purification device of the present invention has a coarse filter 14 at the air inlet at the bottom of the casing to remove various larger coarse impurities. Then the airflow enters the air electrostatic disinfection and purification module 13, where it passes through a high-voltage electric field to disinfect and capture microorganisms. Then, a microporous filter membrane 12 made of H14 grade high-efficiency filter material is used to further capture individual residual nucleic acid fragments of the killed microorganisms to ensure the final purification effect. The ozone removal filter 11 is used to remove ozone from the airflow. The present invention has multiple centrifugal fans 10 arranged side by side at intervals along the left and right horizontal direction in the upper part of the air duct 7. The air inlet of each centrifugal fan 10 is located in the air duct 7. The air outlet of the blower 10 is connected to the air inlet of the arc-shaped jet pipe 15. The arc-shaped jet pipe 15 is set along the front-to-back direction. The cross-section of the arc-shaped jet pipe 15 along the left-to-right vertical direction is rectangular. The air outlet end of each arc-shaped jet pipe 15 is fixedly connected to the upper part of the front panel 2. Each arc-shaped jet pipe 15 is a curved arc with a lower air inlet end and a higher air outlet end. Because the arc-shaped jet pipe 15 at the air outlet is designed as an arc, and the front panel 2 is an arc-shaped plate that gradually bends forward from bottom to top, this design can produce a better fluid adhesion effect and can drive the air around the front panel 2 to flow with the air sprayed from the air outlet, strengthen the air flow in the entire biological laboratory 20, and avoid eliminating dead corners. Therefore, the pathogen nucleic acid aerosol purification device of the present invention has the characteristics of enabling full circulation of air in the biological laboratory without dead corners, ensuring that the air circulation is as free of eddies and cross disturbances as possible, and efficiently disinfecting and removing nucleic acid fragments, viruses and bacterial microorganisms present in the aerosols in the air of the biological laboratory in a very short time, and efficiently removing suspended particulate matter present in the air of the biological laboratory.

Claims

1. A pathogen nucleic acid aerosol decontamination device, characterized by: The application relates to a cabinet, which comprises a frame, a front panel (2), a left side plate (3), a right side plate (4), a back baffle (5) and a top cover plate (6) arranged on the frame, wherein the front panel (2) is an arc-shaped plate with a gradually forward-bent plate surface from bottom to top, the back baffle (5) and the top cover plate (6) are rectangular, the plate surface of the back baffle (5) is located in the left-right vertical direction, and the plate surface of the top cover plate (6) is located in the horizontal direction. The bottom of the cabinet is an air inlet, and the front panel (2), the left side plate (3), the right side plate (4), the back baffle (5) and the top cover plate (6) surround to form an air duct (7) through which air can flow from bottom to top; a plurality of centrifugal fans (10) are arranged in the upper part of the air duct (7) along the left-right horizontal direction; the air inlets of the centrifugal fans (10) are respectively located in the air duct (7); the air outlets of the centrifugal fans (10) are respectively communicated with the air inlets of arc-shaped jet pipes (15); the arc-shaped jet pipes (15) are arranged along the front-back direction; the cross section of the arc-shaped jet pipes (15) along the left-right vertical direction is rectangular; the upper part of the front panel (2) is fixedly connected with the air outlet end of each arc-shaped jet pipe (15); and each arc-shaped jet pipe (15) is a curved arc-shaped pipe with a low air inlet end and a high air outlet end. An ozone-removing filter screen (11) is arranged in the air duct (7) below the centrifugal fans (10) along the horizontal direction; a microporous filter membrane (12) made of H14 high-efficiency filter material is arranged in the air duct (7) below the ozone-removing filter screen (11) along the horizontal direction; and an air electrostatic disinfection and purification module (13) is arranged in the air duct (7) below the microporous filter membrane (12) along the horizontal direction; and a coarse filter screen (14) is arranged at the air inlet of the bottom of the cabinet. A plurality of ultraviolet lamp tubes for sterilization are arranged on the front plate surface of the back baffle (5). The air electrostatic disinfection and purification module (13) comprises a plurality of foam metal plates (16) with plate surfaces through which air flows; the plate surfaces of the foam metal plates (16) are arranged along the front-back vertical direction; and air flow channels (17) are arranged between the foam metal plates (16).

2. The pathogen nucleic acid aerosol purification device according to claim 1, characterized by: The bottom end or side edge of the front panel (2) is connected with the frame through a hinge; the upper part of the front panel (2) is connected with the frame, the left side plate (3) or the right side plate (4) through screws or door bolts; and an air-tight sealing strip is arranged at the edge of the front panel (2).

3. The pathogen nucleic acid aerosol purification device according to claim 2, characterized by: The number of the centrifugal fans (10) is 3-5; the centrifugal fans (10) are adjustable air volume fans; the height of the cabinet along the vertical direction is 1500mm-1700mm; the width of the cabinet along the left-right horizontal direction is 1400mm-1900mm; the width of the top of the cabinet along the front-back direction is 600mm-800mm; and the width of the bottom of the cabinet along the front-back direction is 300mm-500mm.

4. The pathogen nucleic acid aerosol purification device according to claim 1 or 2 or 3, characterized by: A row of discharge electrodes (18) is arranged in the middle part of the air flow channel (17) along the front-back horizontal direction; the plurality of foam metal plates (16) and the discharge electrodes (18) are respectively arranged on an air electrostatic disinfection and purification module frame; and the air electrostatic disinfection and purification module frame is inserted into the air duct (7) through gap fit.

5. The pathogen nucleic acid aerosol purification device according to claim 4, characterized by: The thickness of the foamed metal plate (16) is 5 mm - 15 mm.

6. The pathogen nucleic acid aerosol purification device according to claim 5, characterized by: The number of holes per inch PPI of the foam metal plate (16) is 80-120, the porosity is 98%, and the volume density of the foam metal plate (16) is 0.1 g / cm 3 The through hole rate is not greater than 98%.

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