A drug emulsifying and dispersing device
By adopting a rotating and rushing mechanism linkage design in the drug emulsification and dispersion device, the problem of drug adhering to the barrel wall during the emulsification process is solved, achieving more efficient drug emulsification and lower cleaning and raw material costs.
Patent Information
- Application Number
- CN202311421734.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-10-31
- Publication Date
- 2025-07-01
- Estimated Expiration
- 2043-10-31
AI Technical Summary
During the emulsification process, the existing drug emulsification and dispersion devices are easily attached to the barrel wall due to the difference in liquid depth and height of the liquid and the self-flow of the drug. This affects the emulsification effect and increases the cleaning burden and raw material cost.
A drug emulsification and dispersion device is designed, and a rotating mechanism is used to link it with the rush mechanism. The drug is agitated and swelled along the barrel wall through the sliding block and toggle plate of the rush mechanism. The rush mechanism uses a gear belt and a rush knife to remove the drug. The rush mechanism adjusts the drug drop angle through the rush board and the telescopic motor to improve the emulsification efficiency.
Through the linkage of rotation and rush mechanisms, the drug is evenly dispersed and effectively removed the drug from the barrel wall, improving the emulsification effect, reducing the cleaning burden and raw material costs.
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Figure CN117225237B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of pharmaceutical emulsification, and particularly to a pharmaceutical emulsifying and dispersing device. Background Art
[0002] In the pharmaceutical production process, it is necessary to carry out emulsification processing on the mixed raw materials after solid-liquid mixing. At present, an ordinary stirring emulsification device is used to achieve dispersion and emulsification processing of drugs.
[0003] A pharmaceutical emulsifying and dispersing device is a device widely used in pharmaceutical engineering, which is used to uniformly disperse immiscible drugs and other additives in water or oil for the next processing and production operations. The pharmaceutical emulsifying and dispersing device usually mixes and disperses immiscible drugs and other additives in water or oil by means of high-speed stirring, etc., so as to form a stable emulsion or dispersed liquid system.
[0004] As an indispensable part of the pharmaceutical process, the pharmaceutical emulsifying and dispersing device determines whether the drug can be better dispersed into smaller particles and whether the bioavailability and absorbability can be improved, which plays a very important role in the taste and therapeutic effect of the drug.
[0005] According to the patent number CN112337328A, a drug raw material emulsifying device is disclosed, including a barrel body. The outer wall of the top of the barrel body is connected with a feeding funnel by bolts, and the outer wall of the bottom of the barrel body is connected with a discharging pipe by bolts. The outer wall of the top of the barrel body is connected with a driving motor by bolts, and the output shaft of the driving motor is connected with a rotating shaft by bolts. The circumferential outer wall of the rotating shaft is connected with an inclined extension rod by bolts. In this invention, when the electrical receiver contacts the power supply conductor, the power supply conductor supplies power to the electromagnet block. The electromagnet block is energized and has magnetism and repels the movable ring. The movable ring slides along the extension rod to the end far from the electromagnet block. When the electrical receiver does not contact the power supply conductor, the electromagnet block loses magnetism, and the movable ring slides to the end close to the electromagnet block due to the inertia of the rotation of the extension rod, ensuring that during the process of the extension rod stirring the raw materials, the movable ring and the movable teeth reciprocate to further stir the raw materials, improving the emulsification efficiency.
[0006] However, during the emulsification and dispersion process, due to the height difference in the depth of the liquid in the barrel, and the drug enters the barrel and mixes with the liquid medicine in a self-flowing manner, such a method will not only make the drug easily adhere to the barrel wall, resulting in the drug not being able to fully contact the liquid medicine, so that the drug cannot be fully emulsified, affecting the emulsification effect, but also the drug adhering to the barrel wall increases the cleaning burden and the cost of pharmaceutical raw materials. For this reason, we propose a pharmaceutical emulsifying and dispersing device. Summary of the Invention
[0007] The object of the present invention is to provide a drug emulsifying and dispersing device to solve the problems raised in the above-mentioned background technology.
[0008] To achieve the above-mentioned object, the present invention provides the following technical solutions: a drug emulsifying and dispersing device, comprising a barrel, wherein the barrel is provided with a dispersing component for dispersing and emulsifying the drug;
[0009] The barrel body is provided with a fusion component for drug emulsification;
[0010] The fusion component comprises a plurality of tumbling mechanisms for scraping off the medicine on the inner wall of the barrel body and a rejection mechanism for removing the medicine on the surface of the tumbling mechanism, and the tumbling mechanism is connected with the dispersion component.
[0011] Preferably, the dispersing assembly includes a rotating mechanism for dispersing the medicine along the circumference of the barrel and an adjusting mechanism for adjusting the drug dispersing angle.
[0012] Preferably, the tumbling mechanism comprises a mounting plate, a slide rail is provided on the mounting plate, a sliding block moving along the slide rail track is provided in the slide rail, and abutment members for limiting the movement of the sliding block are provided at both upper and lower ends of the slide rail;
[0013] The sliding block is connected to the toggle plate via a connecting shaft, a first limiting groove is formed on the connecting shaft, and a second limiting groove is formed on the mounting plate, and a limiting block for limiting the rotation of the sliding block is formed through the first limiting groove and the second limiting groove;
[0014] The mounting plate is connected to the dispersion assembly, and the sliding block is connected to the dispersion assembly via a cylinder device. The cylinder device pushes the sliding block to move along the slide track, so that the toggle plate can perform a circular motion along the slide track.
[0015] Preferably, the abutment member comprises a fixed block, an abutment block is provided at one end of the fixed block, and an elastic member is provided between the abutment block and the fixed block.
[0016] Preferably, the outer track of the slide rail is the same as the track of the inner wall of the barrel body.
[0017] Preferably, the abutment block is provided with a guide surface. The upper and lower abutment blocks are symmetrically arranged along the center of the slide rail, and when the sliding block contacts the guide surface, the abutment block compresses the elastic member to allow the sliding block to pass.
[0018] Preferably, the rejection mechanism includes a limit frame installed on the toggle plate, and a driving gear and multiple groups of driven gears are respectively provided in the limit frame along the circumference of the toggle plate, the driving gear is connected to the gear motor, and a gear belt is provided on the outer side of the driving gear and the driven gear, and a rejection knife is provided on the gear belt; the rejection knife contacts the outer wall of the toggle plate; when the toggle plate is scraping along the inner wall of the barrel body, the rejection knife moves to a position away from the inner wall of the barrel body, so that the rejection knife and the barrel body do not interfere with each other.
[0019] The gear motor drives the driving gear, the gear belt and the driven gear to rotate, so that the rejecting knife removes the medicine along the outer wall of the toggle plate.
[0020] Preferably, the rotating mechanism comprises a stirring shaft, a rotating motor is provided at the bottom of the barrel, an output end of the rotating motor extends into the barrel and is connected to the stirring shaft, a drug storage bin is connected to the stirring shaft, and a discharge port is provided on the outer wall of the drug storage bin at equal intervals along its circumferential direction;
[0021] And the stirring shaft is connected to the mounting plate.
[0022] Preferably, the adjustment mechanism includes multiple groups of adjustment plates, the adjustment plates are located above the discharge port, and an adjustment rod is provided on one side of the adjustment plate; the adjustment rod is rotatably installed on the top of the medicine storage bin, and the adjustment rods are jointly connected to a telescopic motor, and the telescopic motor is fixed on the top of the medicine storage bin.
[0023] The telescopic motor drives the adjusting rod to move and adjust the angle between the adjusting plate and the feeding port.
[0024] Preferably, the bottom of the medicine storage bin is arc-shaped.
[0025] Compared with the prior art, the present invention has the following beneficial effects:
[0026] 1. The present invention links the rotating mechanism with the tumbling mechanism, and the medicine falls along the storage bin. The medicine discharged through the discharge port is evenly dispersed into the barrel under the centrifugal action. In the process of uniform dispersion and falling of the medicine, the toggle plate can move along the slide rail, and the evenly dispersed medicine is stirred along the barrel wall and the medicine and the material in the barrel are tumbled up and down, thereby increasing the emulsification of the medicine, and the medicine attached to the inner wall of the barrel can be removed during the movement. The structural design of the tumbling mechanism further improves the emulsification effect, while reducing the burden of cleaning and the cost of medicine raw materials.
[0027] 2. The present invention provides a rejecting piece, and uses a rejecting knife to move along the outer wall of the toggle plate under the drive of the gear belt, so that the medicines fallen on the outer wall of the toggle plate are removed, further ensuring the cleaning effect of the tumbling mechanism.
[0028] 3. The present invention uses an adjusting mechanism to collide the medicine scattered outward by centrifugation with an adjusting plate, and can adjust the angle between the adjusting plate and the discharge port during use, so that the medicine collides with the adjusting plate at different angles and falls at different angles, thereby accelerating the efficiency of drug emulsification. BRIEF DESCRIPTION OF THE DRAWINGS
[0029] Figure 1 It is a schematic diagram of the overall isometric structure of the present invention;
[0030] Figure 2 It is a schematic diagram of the cross-sectional structure of the whole part of the present invention;
[0031] Figure 3 It is a partial structural schematic diagram of the rotating mechanism of the present invention;
[0032] Figure 4 It is a partial structural schematic diagram of the regulating mechanism of the present invention;
[0033] Figure 5 It is a schematic diagram of the structure of the mounting plate of the present invention;
[0034] Figure 6 For the present invention Figure 5 The enlarged structural diagram at A in the middle;
[0035] Figure 7 It is a partial structural schematic diagram of the rejecting mechanism of the present invention;
[0036] Figure 8 This is a schematic diagram of the drug emulsification process structure of the present invention;
[0037] Figure 9 This is a schematic diagram of the sliding block moving track structure of the present invention;
[0038] Figure 10 It is a schematic diagram of the moving trajectory structure of the rejecting knife of the present invention.
[0039] In the figure: 100-barrel body; 1-dispersion component; 11-rotation mechanism; 12-adjustment mechanism; 2-fusion component; 21-overturning mechanism; 211-mounting plate; 212-slide rail; 213-sliding block; 214-abutment member; 2141-fixed block; 2142-abutment block; 21421-slide guide surface; 2143-elastic member; 215-connecting shaft; 216-sliding plate; 217-first limiting groove; 218-second limiting groove; 219-limiting block; 22-rejection mechanism; 221-limiting frame; 222-driving gear; 223-driven gear; 224-gear belt; 225-rejection knife; 111-agitation shaft; 112-medicine storage bin; 113-feeding port; 121-adjustment plate; 122-adjustment rod. DETAILED DESCRIPTION
[0040] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without making creative efforts shall fall within the protection scope of the present invention.
[0041] Embodiment 1
[0042] Please refer to Figure 1 , the present invention provides a technical solution: a drug emulsifying and dispersing device, including a barrel body 100, and a dispersing component 1 for dispersing and emulsifying drugs is arranged in the barrel body 100;
[0043] A fusion component 2 for emulsifying drugs is arranged in the barrel body 100;
[0044] The fusion component 2 includes multiple sets of surging mechanisms 21 for scraping the drugs on the inner wall of the barrel body 100 and a removing mechanism 22 for removing the drugs on the surface of the surging mechanism 21, and the surging mechanism 21 is connected to the dispersing component 1;
[0045] In the present invention, the drugs used can be granular drugs for emulsification, and the removing knife 112 can be provided with air holes for inhalation the same as those in the comparative document, which are not marked in the figure;
[0046] And a feed port is also arranged on the barrel body 100, which is convenient for the emulsification of two drugs, and all belong to the prior art and will not be elaborated here.
[0047] Further, the dispersing component 1 includes a rotating mechanism 11 for dispersing drugs along the circumferential direction of the barrel body 100 and an adjusting mechanism 12 for adjusting the dispersing angle of the drugs;
[0048] The rotating mechanism 11 and the adjusting mechanism 12 can promote the dispersion of drugs into the barrel body 100 to uniformly emulsify the drugs.
[0049] Further, please refer to Figure 2 and Figure 5 , the surging mechanism 21 includes a mounting plate 211, a slide rail 212 is arranged on the mounting plate 211, a sliding block 213 moving along the track of the slide rail 212 is arranged in the slide rail 212, and abutting members 214 for restricting the movement of the sliding block 213 are arranged at both the upper and lower ends of the slide rail 212;
[0050] The sliding block 213 is connected to a toggle plate 216 via a connecting shaft 215. A first limiting groove 217 is formed on the connecting shaft 215, and a second limiting groove 218 is formed on the mounting plate 211. A limiting block 219 is formed through the first limiting groove 217 and the second limiting groove 218 to limit the rotation of the sliding block 213.
[0051] The mounting plate 211 is connected to the dispersion component 1, and the sliding block 213 is connected to the dispersion component 1 through a cylinder device. The cylinder device pushes the sliding block 213 to move along the track of the slide rail 212, so that the toggle plate 216 can perform a circular motion along the track of the slide rail 212;
[0052] For further information, see Figure 6 The abutment member 214 includes a fixed block 2141, an abutment block 2142 is provided at one end of the fixed block 2141, and an elastic member 2143 is provided between the abutment block 2142 and the fixed block 2141, and the elastic member 2143 is preferably a spring.
[0053] Furthermore, the outer track of the slide rail 212 is the same as the inner track of the barrel body 100 .
[0054] Furthermore, a guide sliding surface 21421 is provided on the abutment block 2142; the upper and lower abutment blocks 2142 are symmetrically arranged along the center of the slide rail 212, and when the sliding block 213 contacts the guide sliding surface 21421, the abutment block 2142 will compress the elastic member 2143 to allow the sliding block 213 to pass.
[0055] During the emulsification process, after the drug enters the barrel body 100, the cylinder can push the sliding block 213 to move along the track of the slide rail 212. The track of the slide rail 212 is the same as the track of the inner wall of the barrel body 100, and is an integrated elliptical track, so that the sliding block 213 can move a cycle, so that the sliding block 213 can drive the toggle plate 216 to move from bottom to top close to the inner wall of the barrel body 100. In order to prevent the sliding block 213 from rotating during the movement of the track, the limiting block 219 is used to slide in the first limiting groove 217 and the second limiting groove 218 so that it does not rotate during the movement of the sliding block 213 along the slide rail 212. The sliding block 213 will rotate to play a limiting role, and in order to prevent the sliding block 213 from retreating or moving to the wrong position when it moves to the highest and lowest points of the slide rail 212, the abutment block 2142 is used to limit the position of the corner of the slide rail 212, which can not only enable the fluctuation block to scrape off the medicine scattered on the inner wall of the barrel 100, but also enable the toggle plate 216 to move up and down in a circle along the center of the barrel 100, so that the medicine can be immersed and driven upward during the stirring process, and the two are fully in contact, thereby solving the problem of the medicine being scattered and falling on the inner wall of the barrel 100 during the emulsification process and promoting the emulsification efficiency;
[0056] For further information, seeFigures 3 - 4 The rotation mechanism 11 includes a stirring shaft 111. A rotating motor is provided at the bottom of the barrel body 100. The output end of the rotating motor extends into the barrel body 100 and is connected to the stirring shaft 111. A medicine storage bin 112 is connected to the stirring shaft 111. Material discharging openings 113 are equidistantly arranged on the outer wall of the medicine storage bin 112 along the circumferential direction thereof.
[0057] And the stirring shaft 111 is connected to the mounting plate 211.
[0058] The bottom of the medicine storage bin 112 is arc-shaped.
[0059] First, during use, the medicine to be emulsified is placed into the storage bin 113. During the operation of the equipment, driven by the stirring shaft 111, under the action of centrifugation, the medicine can be dispersed in the circumferential direction of the barrel 100 through the material discharging opening 114 of the storage bin 113 and fall into the barrel body 100 to be fully mixed with the liquid, thereby further improving the emulsification effect of the medicine. Further, please refer to Figure 5 , Figure 7 and Figure 10 , the rejection mechanism 22 includes a limit frame 221 installed on the toggle plate 216. Along the circumferential direction of the toggle plate 216 in the limit frame 221, a driving gear 222 and multiple groups of driven gears 223 are respectively provided. The driving gear 222 is connected to a gear motor. A gear belt 224 is provided outside the driving gear 222 and the driven gears 223. A rejection knife 225 is provided on the gear belt 224. The rejection knife 225 contacts the outer wall of the toggle plate 216. When the toggle plate 216 scrapes along the inner wall of the barrel body 100, the rejection knife 225 runs to a position far from the inner wall of the barrel body 100, so that there is no interference between the rejection knife 225 and the barrel body 100.
[0060] The gear motor drives the driving gear 222, the gear belt 224 and the driven gears 223 to rotate, so that the rejection knife 225 removes the medicine along the outer wall of the toggle plate 216; the bottom of the medicine storage bin 112 is arc-shaped.
[0061] During the emulsification of the medicine, the toggle plate 216 scrapes the medicine adhered to the inner wall of the barrel body 100. The scraped medicine will accumulate at the position between the toggle plate 216 and the inner wall of the barrel body 100. The gear motor drives the driving gear 222 and the driven gears 223, so that the conveyor belt continuously runs in the limit frame 221.
[0062] It should be noted that, when the toggle plate 216 is scraping along the inner wall of the barrel body 100, the removal knife 225 moves to the opposite position so that the two do not interfere with each other. When the toggle plate 216 moves to the inner side of the slide rail 212, the removal knife 225 can move to the outer wall where the toggle plate 216 contacts the inner wall of the barrel body 100, thereby cleaning the medicine on the inner wall of the barrel body 100, thereby achieving the cleaning effect of the medicine.
[0063] For further information, see Figure 4 The adjustment mechanism 12 includes multiple groups of adjustment plates 121, and the adjustment plates 121 are located above the discharge port 113. An adjustment rod 122 is provided on one side of the adjustment plate 121; the adjustment rod 122 is rotatably installed on the top of the medicine storage bin 112, and the adjustment rod 122 is commonly connected to a telescopic motor, and the telescopic motor is fixed on the top of the medicine storage bin 112.
[0064] The telescopic motor drives the adjusting rod 122 to move, and adjusts the angle between the adjusting plate 121 and the material discharge port 113;
[0065] When the medicine is discharged from the storage bin, under the action of centrifugal force, the granular medicine collides with the adjustment plate 121 at the discharge port 113, and is blocked and collided with by the adjustment plate 121, and can fall into the barrel 100 at different angles to be emulsified, thereby achieving a better emulsification effect during the emulsification process.
[0066] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.
[0067] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A drug emulsifying and dispersing device, comprising a barrel body (100), characterized in that: The barrel (100) is provided with a dispersing component (1) for dispersing and emulsifying the drug; A fusion component (2) for drug emulsification is provided in the barrel (100); The fusion component (2) comprises a plurality of tumbling mechanisms (21) for scraping off drugs on the inner wall of the barrel (100) and a removal mechanism (22) for removing drugs on the surface of the tumbling mechanisms (21), and the tumbling mechanisms (21) are connected to the dispersion component (1); The tumbling mechanism (21) comprises a mounting plate (211), a slide rail (212) is provided on the mounting plate (211), a sliding block (213) is provided in the slide rail (212) and moves along the track of the slide rail (212), and abutment members (214) for limiting the movement of the sliding block (213) are provided at both upper and lower ends of the slide rail (212); The sliding block (213) is connected to a toggle plate (216) via a connecting shaft (215); a first limiting groove (217) is provided on the connecting shaft (215); a second limiting groove (218) is provided on the mounting plate (211); a limiting block (219) is slidably provided in the second limiting groove (218); the limiting block (219) passes through the first limiting groove (217) and is used to limit the rotation of the sliding block (213); the mounting plate (211) is connected to the dispersion component (1); and the sliding block (213) is connected to the dispersion component (1) via a cylinder device; The abutment member (214) comprises a fixed block (2141), an abutment block (2142) is provided at one end of the fixed block (2141), and an elastic member (2143) is provided between the abutment block (2142) and the fixed block (2141); The outer track of the slide rail (212) is the same as the inner track of the barrel body (100); The abutment block (2142) is provided with a guide sliding surface (21421), and the upper and lower abutment blocks (2142) are symmetrically arranged along the center of the slide rail (212); when the sliding block (213) contacts the guide sliding surface (21421), the abutment block (2142) compresses the elastic member (2143) to allow the sliding block (213) to pass through; The rejecting mechanism (22) comprises a limit frame (221) mounted on the toggle plate (216), and a driving gear (222) and a plurality of groups of driven gears (223) are respectively arranged in the limit frame (221) along the circumference of the toggle plate (216), the driving gear (222) is connected to a gear motor, a gear belt (224) is arranged on the outer sides of the driving gear (222) and the driven gear (223), a rejecting knife (225) is arranged on the gear belt (224), and the rejecting knife (225) contacts the outer wall of the toggle plate (216); when the toggle plate (216) is scraping along the inner wall of the barrel body (100), the rejecting knife (225) moves to a position away from the inner wall of the barrel body (100), so that the rejecting knife (225) and the barrel body (100) do not interfere with each other.
2. The pharmaceutical emulsifying and dispersing device according to claim 1, characterized in that: The dispersion component (1) includes a rotating mechanism (11) for circumferentially dispersing the drug along the barrel body (100) and an adjusting mechanism (12) for adjusting the drug dispersion angle.
3. A drug emulsifying and dispersing device according to claim 2, characterized in that: The rotating mechanism (11) includes a stirring shaft (111). A rotating motor is provided at the bottom of the barrel body (100). The output end of the rotating motor extends into the barrel body (100) and is connected to the stirring shaft (111). A medicine storage bin (112) is connected to the stirring shaft (111). Feeding ports (113) are equidistantly arranged along the circumferential direction of the outer wall of the medicine storage bin (112). And the stirring shaft (111) is connected to the mounting plate (211).
4. The pharmaceutical emulsifying and dispersing device according to claim 3, characterized in that: The adjusting mechanism (12) includes multiple groups of adjusting plates (121). The adjusting plates (121) are located above the feeding ports (113). An adjusting rod (122) is provided on one side of the adjusting plate (121). The adjusting rod (122) is rotatably installed at the top of the medicine storage bin (112). The adjusting rods (122) are commonly connected to a telescopic motor, and the telescopic motor is fixed to the top of the medicine storage bin (112).
5. A drug emulsifying and dispersing device according to claim 3, characterized in that: The bottom of the medicine storage bin (112) is arc-shaped.
Citation Information
Patent Citations
Medicine raw material emulsifying device
CN112337328A
Preparation treatment process of titanium dioxide for cosmetic production
CN115178348A