A sample cryogenic storage system

CN117249633BActive Publication Date: 2026-11-03SHANGHAI ORIGINCELL BIOLOGICAL CRYO EQUIP CO LTD
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Patent Information

Application Number
CN202311299107.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-10-09
Publication Date
2026-11-03
Estimated Expiration
2043-10-09

AI Technical Summary

Technical Problem

In existing cryopreservation equipment, the lift-up well mechanism occupies a large space and is inconvenient, resulting in low sample extraction efficiency, especially in large-capacity storage refrigerators where operation is inconvenient.

Method used

The lifting well assembly moves within the storage compartment, combined with the shovel assembly, rotating gripping assembly, and opening assembly, to achieve basket lifting, rack shoveling, and sample rotation gripping. It also docks with the operating compartment through a lifting mechanism to improve storage and retrieval efficiency.

Benefits of technology

By lifting the well assembly and rotating the gripping assembly 360 degrees, efficient access to the basket inside the large-capacity storage compartment is achieved, saving space and improving the efficiency of sample access.

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Abstract

The application discloses a kind of sample cryogenic storage systems, including including operation cabin, and storage cabin;Operation cabin is set on storage cabin, and can be accessed to the sample in storage cabin Operation;Multiple storage ports are set in the upper end surface of storage cabin;Lifting well assembly is set in operation cabin, lifting well assembly is movably set in operation cabin;Lifting well assembly can be moved to each storage port, and the basket in storage cabin is lifted.The beneficial effects of the application are that the basket in the operation cabin is lifted by the lifting well assembly, the board frame of the basket can be pushed out by the shovel plate assembly, the board frame or sample can be grabbed by rotating the rotating grabbing assembly 360 degrees, the transfer tank can be jacked up and connected with the operation cabin by the jacking mechanism, the rotating grabbing assembly can store the sample or board frame in the transfer tank into the basket through the shovel plate assembly and the lifting well assembly, and then into the storage cabin, thereby greatly improving the work efficiency.
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Description

Technical Field

[0001] This invention relates to the field of sample storage technology, and in particular to a low-temperature sample storage system. Background Technology

[0002] In the biomedical field, sample cryopreservation equipment is used to store biological samples such as blood samples, vaccines, and bacterial / viral strains at low temperatures, keeping the samples in liquid nitrogen for long-term viability preservation. The equipment contains multiple sample boxes, each containing multiple test tubes; the sample to be stored is contained within one of these test tubes.

[0003] In current cryopreservation equipment, during the extraction of biological samples, a lifting well mechanism needs to be added above the storage device to lift the basket out of the storage device, and then the sample box inside the basket is exported through an external fixed shovel mechanism. This not only occupies a lot of space, but the fixed lifting well mechanism is also more convenient. For larger storage refrigerators, it is inconvenient to extract the basket, which reduces work efficiency. Therefore, there is an urgent need for a sample storage and retrieval system. Summary of the Invention

[0004] The purpose of this section is to outline some aspects of embodiments of the present invention and to briefly describe some preferred embodiments. Simplifications or omissions may be made in this section, as well as in the abstract and title of this application, to avoid obscuring the purpose of these documents; however, such simplifications or omissions should not be construed as limiting the scope of the invention.

[0005] In view of the problems existing in the above or prior art, the present invention is proposed.

[0006] Therefore, the purpose of this invention is to provide a low-temperature sample storage system that can move within a storage chamber via a lift-up assembly. The lift-up assembly raises a basket from the storage chamber, a shovel assembly scoops up sample trays from the basket, a rotating gripper assembly transfers the sample trays, and the rotating gripper assembly can also pick up samples from the trays. A lifting mechanism connects the transfer tank to the operating chamber, and the rotating gripper assembly opens the top cover of the transfer tank and places it aside. The opening assembly opens the insulation cover of the storage chamber.

[0007] To solve the above-mentioned technical problems, the present invention provides the following technical solution: a sample low-temperature storage system, which includes an operation chamber and a storage chamber; the operation chamber is disposed above the storage chamber and can perform storage and retrieval operations on the samples in the storage chamber;

[0008] The upper surface of the storage compartment has multiple storage ports;

[0009] The operating compartment is equipped with a lifting well assembly, which is movably installed within the operating compartment. The lifting well assembly can be moved to the corresponding storage port to lift the baskets inside the storage compartment.

[0010] As a preferred embodiment of the low-temperature storage system for samples of the present invention, the operating chamber is further provided with a rotating gripping component, which can be raised, lowered, and rotated to grip biological plates or biological samples.

[0011] As a preferred embodiment of the low-temperature storage system for samples of the present invention, a shovel assembly is provided around the lifting well assembly, and a plate rack storage channel is provided on the lifting well assembly. The shovel assembly can scoop or store the basket through the plate rack storage channel.

[0012] As a preferred embodiment of the low-temperature storage system for samples of the present invention, the operating chamber is further provided with a cover opening component, which can lift and grab the insulation cover on the storage port.

[0013] As a preferred embodiment of the low-temperature storage system for samples of the present invention, the lifting well assembly includes a supporting moving part, a supporting shell sliding part, and a lifting hook part;

[0014] The supporting movable component is slidably connected to the operating cabin, and the supporting shell sliding component is slidably connected to the supporting movable component vertically or laterally. A lifting hook is installed inside the supporting shell sliding component, which can lift the basket in the storage cabin through the storage port.

[0015] As a preferred embodiment of the low-temperature storage system for samples of the present invention, the supporting shell sliding component includes a supporting shell, a supporting shell horizontal sliding frame, a supporting shell vertical sliding support frame, a supporting shell vertical guide rail, and a vertical slider.

[0016] The bottom sides of both ends of the horizontal sliding frame of the support housing are horizontally slidably connected to the first guide rail and the second guide rail of the support housing. One side of the horizontal sliding frame of the support housing is connected to the vertical sliding support frame of the support housing. The vertical sliding support frame of the support housing is provided with a vertical guide rail and a first drive mechanism. A vertical straight slot is opened on the side of the vertical sliding support frame of the support housing. The vertical slider is slidably connected to the vertical guide rail of the support housing. The vertical slider is connected to the support housing through a connecting shaft passing through the vertical straight slot. The support housing is located between the first guide rail and the second guide rail of the support housing. A vertical guide rail shaft is provided on the side of the support housing. A vertical guide rail shaft slider is provided on the side of the vertical sliding support frame of the support housing. The vertical guide rail shaft and the vertical guide rail shaft slider are vertically slidably connected.

[0017] As a preferred embodiment of the low-temperature storage system for samples of the present invention, the lifting hook includes a handle slider, a lifting part, a handle slider guide rail, an arc-shaped stop, and a rotating lifting component.

[0018] The handle slider guide rail is set on the inner wall of the support housing. The handle slider is vertically slidably connected to the handle slider guide rail. The lower end face of the handle slider is connected to the lifting part. The support housing is provided with a second drive mechanism. The second drive mechanism can drive the rotating lifting component to rotate. The rotating lifting component is connected to the handle slider. The rotating lifting component can drive the handle slider to rise and fall along the handle slider guide rail. The arc-shaped stop is set on the upper side of the inner wall of the support housing.

[0019] As a preferred embodiment of the low-temperature storage system for samples of the present invention, the rotating gripping component includes a rotating gripper, a pipette gripper, and a gripping support shaft.

[0020] The two ends of the gripping support shaft are slidably connected to the inside of the operating cabin, and the suction gripper and the gripping support shaft are slidably connected to the two sides of the gripping support shaft respectively.

[0021] As a preferred embodiment of the low-temperature storage system for samples of the present invention, the rotating gripper includes a gripper support transverse slide plate, a vertical travel plate, a rotating shaft drive component, a rotating shaft, a gripper frame, a gripper, and a gripper drive mechanism.

[0022] The gripper supports the horizontal sliding plate and the gripping support shaft side are slidably connected. The vertical travel plate is vertically slidably connected to the side of the gripper supports the horizontal sliding plate. The lower end of the vertical travel plate is connected to the rotating shaft drive component. The rotating shaft drive component is connected to one end of the rotating shaft. The other end of the rotating shaft is connected to the gripper frame. A gripper drive mechanism is provided inside the gripper frame. The gripper drive mechanism drives the gripper to clamp the biological board frame.

[0023] As a preferred embodiment of the sample low-temperature storage system of the present invention, the straw gripper includes a straw support shaft, a straw vertical sliding plate, a straw support block, a straw, and a liquid nitrogen cylinder.

[0024] The straw support shaft is slidably connected to the other side of the gripping support shaft, the straw vertical slide is vertically slidably connected to the straw support shaft, the straw support block is connected to the straw vertical slide, the straw support block and the straw, and a liquid nitrogen cylinder is set around the straw. The straw can draw liquid nitrogen from the cryopreservation tube.

[0025] In a preferred embodiment of the low-temperature storage system for samples of the present invention, the shovel assembly includes a shovel and a storage component;

[0026] The storage unit is equipped with a shovel, which can push the biological board rack in the basket out through the board rack storage channel, and the storage unit can push the biological board rack into the basket through the board rack storage channel.

[0027] As a preferred embodiment of the low-temperature storage system for samples of the present invention, the storage components include a shovel plate, a sliding push plate, a push block, a sliding push plate support plate, a straight toothed plate, a straight toothed plate meshing gear, a gear drive mechanism, and a support housing.

[0028] The shovel plate is located at the lower end of the inner side of the plate rack storage channel and is connected to the support shell. The outer side of the support shell is connected to the sliding push plate support plate. The sliding push plate is slidably connected to the sliding push plate support plate. The sliding push plate is sleeved on the outer side of the support shell and is connected to the push block. A spur plate is connected to one side of the sliding push plate. The gear drive mechanism is connected to the meshing gear of the spur plate. The meshing gear of the spur plate is meshed with the spur plate. The sliding push plate support plate is connected to the gear drive mechanism.

[0029] As a preferred embodiment of the low-temperature storage system for samples of the present invention, the scooping component includes a push rod, a push rod toothed plate, a push rod toothed plate support shaft, and a push rod driving mechanism.

[0030] The push rod spur gear support shaft is connected to the sliding push plate support plate. The push rod spur gear support shaft is located at the end away from the push block. The push rod spur gear is slidably connected to the push rod spur gear support shaft. The front end of the push rod spur gear is connected to the push rod. The upper end of the push rod spur gear is meshed with the push rod drive mechanism. The meshing gear of the push rod spur gear can drive the push rod drive mechanism.

[0031] As a preferred embodiment of the low-temperature storage system for samples of the present invention, the opening assembly includes an opening support shaft, a driving lifting mechanism, a telescopic rod, a support rod, a hook portion, and a guide rod.

[0032] The cover opening support shaft is slidably connected to the inside of the operating cabin. The drive lifting mechanism is set on the cover opening support shaft. The upper end of the telescopic rod is connected to the drive lifting mechanism, the lower end of the telescopic rod is connected to the support rod, the two ends of the support rod are connected to the hook part, and the guide rod is connected to the support rod.

[0033] As a preferred embodiment of the low-temperature storage system for samples of the present invention, it further includes a lifting mechanism that can drive the transfer tank to be lifted and docked with the operating cabin, and the operating cabin has a transfer tank passage opening.

[0034] As a preferred embodiment of the low-temperature storage system for samples of the present invention, the lifting mechanism includes a seventh driving component, a seventh guide rail, a seventh lifting frame, and a series conveyor belt.

[0035] The seventh lifting frame is vertically slidably connected to the seventh guide rail. The upper end of the seventh lifting frame can be used to place the intermediate tank. The seventh driving component can drive the seventh lifting frame to rise and fall along the seventh guide rail. The series conveyor belt is set on the upper end of the seventh guide rail.

[0036] As a preferred embodiment of the low-temperature sample storage system of the present invention, the operation chamber further includes an identification entry component and a rotating cleaning component. The identification entry component can identify the barcode of the sample or shelf, and the rotating cleaning component can scan the sample or shelf.

[0037] The beneficial effects of this invention are as follows: 1. This invention allows for the storage of samples within baskets via a storage compartment, which can store multiple baskets; 2. The target basket can be lifted by moving and raising the lifting well assembly within the operating compartment. The movable lifting well assembly facilitates lifting baskets within a large-capacity storage compartment and saves significant space; 3. The lifting and raising of the baskets via the lifting well assembly allows each layer of the basket's shelf or storage slot to be positioned within the shelf storage channel; 4. The shovel assembly allows for the shoveling or storage of shelves at each layer of the basket; 5. The 360-degree rotation of the gripping assembly... 6. Rotation allows for the scooping or storage of biological plates on the baskets within the operating chamber; 7. Rotation of the gripper on the rotating gripping assembly allows for the grabbing of plates or sample tubes within the operating chamber for rotational scanning and cleaning; 8. The opening assembly allows for the lifting and movement of the insulation cover on the storage chamber, which closes the storage opening and insulates the storage chamber; 9. The lifting mechanism allows for the lifting of the transfer tank and docking with the operating chamber. The rotating gripping assembly allows for the storage of samples or plates from the transfer tank into the basket via the shovel assembly and lifting well assembly, thus storing them in the storage chamber, significantly improving work efficiency. Attached Figure Description

[0038] To more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the following description of the embodiments will be briefly introduced. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Wherein:

[0039] Figure 1 This is a schematic diagram of the overall low-temperature storage system for samples.

[0040] Figure 2 This is a schematic diagram of the operating chamber of a sample cryogenic storage system.

[0041] Figure 3 This is a cross-sectional view of the storage chamber of the sample cryogenic storage system.

[0042] Figure 4 This is a three-dimensional view of the storage chamber of the sample cryogenic storage system.

[0043] Figure 5 This is a schematic diagram of the lid-opening component of a low-temperature sample storage system.

[0044] Figure 6This is a schematic diagram of the rotating gripping component and the lifting well component of the sample cryogenic storage system.

[0045] Figure 7 This is a three-dimensional schematic diagram of the rotating gripping component of a sample cryogenic storage system.

[0046] Figure 8 This is a schematic diagram of the sliding component of the support shell for a low-temperature storage system for samples.

[0047] Figure 9 This is a schematic diagram of the spatula assembly of a sample cryogenic storage system.

[0048] Figure 10 This is a partial cross-sectional view of the sliding component of the support shell of the sample cryogenic storage system.

[0049] Figure 11 This is a schematic diagram of the spatula assembly of a sample cryogenic storage system.

[0050] Figure 12 This is a schematic diagram of the lifting hook for retrieving parts from a low-temperature sample storage system.

[0051] Figure 13 This is a magnified view of a portion of the lifting hook used to retrieve parts from a low-temperature sample storage system.

[0052] Figure 14 This is a schematic diagram of the rotating gripping component of a sample cryogenic storage system.

[0053] Figure 15 This is a schematic diagram of the lifting component of a low-temperature sample storage system.

[0054] Figure 16 This is a schematic diagram of the lifting component of a low-temperature sample storage system.

[0055] Figure 17 This is a schematic diagram of the rotating cleaning component of a low-temperature sample storage system.

[0056] Figure label:

[0057] 1. Operation compartment; 2. Storage compartment; 3. Lifting shaft assembly; 4. Rotary gripping assembly; 5. Shovel assembly; 6. Opening assembly; 7. Support moving component; 8. Support housing sliding component; 9. Lifting hook component; 10. Support housing; 11. Support housing transverse sliding frame; 12. Support housing vertical sliding support frame; 13. Support housing vertical guide rail; 14. Vertical slider; 15. Handle slider; 16. Handle slider. ; Lifting part, 3302; Handle slider guide rail, 3303; Arc-shaped stop, 3305; Rotating lifting component, 3304; Rotating gripper, 41; Straw gripper, 42; Gripping support shaft, 43; Gripping support transverse slide plate, 4101; Vertical travel plate, 4102; Rotating shaft drive component, 4103; Rotating shaft, 4104; Gripping frame, 4105; Gripping gripper, 4106; Gripping drive mechanism, 4107; Straw support shaft 4201; Straw vertical slide plate, 4202; Straw support block, 4203; Straw, 4204; Liquid nitrogen cylinder, 4205; Shovel, 51; Storage component; 52; Shovel plate, 5201; Sliding push plate, 5202; Push block, 5203; Sliding push plate support plate, 5204; Straight tooth plate, 5205; Straight tooth plate meshing gear, 5206; Gear drive mechanism, 5207; Support housing, 3201; Push rod, 5101; Push rod spur gear plate, 5102; push rod spur gear plate support shaft, 5103; push rod drive mechanism, 5104; cover opening support shaft, 601; drive lifting mechanism, 602; telescopic rod, 603; support rod, 604; hook part, 605; guide rod, 606; lifting mechanism, 7; seventh drive component, 701; seventh guide rail, 702; seventh lifting frame, 703; tandem conveyor belt, 704; identification and warehousing component, 8; rotating cleaning component, 9. Detailed Implementation

[0058] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0059] Many specific details are set forth in the following description in order to provide a full understanding of the invention. However, the invention may also be practiced in other ways different from those described herein, and those skilled in the art can make similar extensions without departing from the spirit of the invention. Therefore, the invention is not limited to the specific embodiments disclosed below.

[0060] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in one embodiment" appearing in different places in this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that is mutually exclusive with other embodiments.

[0061] Example 1

[0062] Reference Figures 1-4 This is the first embodiment of the present invention. This embodiment provides a sample cryogenic storage system, which includes an operation chamber 1 and a storage chamber 2. The storage chamber 2 can store multiple sets of baskets, and the baskets can store multiple sets of biological racks. Biological samples are placed in the racks. The lifting well assembly 3 can move and lift the baskets in the storage chamber 2 into the operation chamber 1.

[0063] Specifically, it includes an operation compartment 1 and a storage compartment 2; the operation compartment 1 is located above the storage compartment 2 and can perform storage and retrieval operations on the samples in the storage compartment 2.

[0064] Multiple storage ports are provided on the upper surface of storage compartment 2;

[0065] The operating compartment 1 is equipped with a lifting well assembly 3, which is movably installed within the operating compartment 1. The lifting well assembly 3 can be moved to the corresponding storage ports to lift the baskets in the storage compartment 2.

[0066] In summary, this invention stores multiple baskets within the storage compartment 2, and each basket can hold multiple biological plate racks. Each biological plate rack can hold multiple sample tubes. The target basket is lifted into the storage compartment 2 by the lifting well assembly 3, which moves and elevates within the operating compartment 1. After passing through the storage and retrieval racks, the basket is returned to the storage compartment 2 for freezing. The movable lifting well assembly 3 facilitates the lifting of baskets within the large-capacity storage compartment 2 and saves a significant amount of space.

[0067] Example 2

[0068] Reference Figures 1-17 This is the second embodiment of the present invention. In the previous embodiment, the sample cryogenic storage system includes an operation chamber 1 and a storage chamber 2. The storage chamber 2 can store multiple sets of baskets, and the baskets can store multiple sets of biological racks. Biological samples are placed in the racks. The lifting well assembly 3 can move and lift within the operation chamber 1 to lift the baskets in the storage chamber 2 into the operation chamber 1.

[0069] Specifically, it includes an operation compartment 1 and a storage compartment 2; the operation compartment 1 is located above the storage compartment 2 and can perform storage and retrieval operations on the samples in the storage compartment 2.

[0070] Multiple storage ports are provided on the upper surface of storage compartment 2;

[0071] The operating compartment 1 is equipped with a lifting well assembly 3, which is movably installed within the operating compartment 1. The lifting well assembly 3 can be moved to the corresponding storage ports to lift the baskets in the storage compartment 2.

[0072] Furthermore, the operating cabin 1 is also equipped with a rotating gripping component 4, which can be raised, lowered, and rotated to grip biological plates or biological samples.

[0073] Preferably, the rotary gripper 4 can move in the XYZ axis direction within the operating chamber 1, and the rotary gripper 41 can rotate at any horizontal angle.

[0074] Furthermore, a shovel assembly 5 is provided around the lifting well assembly 3, and a rack storage channel is provided on the lifting well assembly 3. The shovel assembly 5 can scoop or store the basket through the rack storage channel.

[0075] Furthermore, the operating compartment 1 is also equipped with a cover opening component 6, which can lift and grab the insulation cover on the storage port.

[0076] Preferably, the opening assembly 6 can move within the operating chamber 1 and can close the insulation cover on the corresponding storage chamber 2. Insulation covers are provided on multiple storage ports, and the opening assembly 6 can open the insulation covers.

[0077] Furthermore, the lift well assembly 3 includes a support moving part 31, a support housing sliding part 32, and a lifting hook part 33;

[0078] The supporting movable part 31 is slidably connected to the operating cabin 1, and the supporting shell sliding part 32 is slidably connected to the supporting movable part 31 vertically or horizontally. The supporting shell sliding part 32 is provided with a lifting hook 33, which can lift the basket in the storage cabin 2 through the storage port.

[0079] Preferably, the supporting movable member 31 is slidably connected along the inner wall of the operating cabin 1, and the supporting housing sliding member 32 can move laterally or vertically along the supporting movable member 31. Furthermore, a lifting hook 33 is provided on the inner side of the supporting housing sliding member 32, and the lifting hook 33 can slide up and down along the inner side of the supporting housing sliding member 32.

[0080] Furthermore, the supporting housing sliding member 32 includes a supporting housing 3201, a supporting housing transverse sliding frame 3202, a supporting housing vertical sliding support frame 3203, a supporting housing vertical guide rail 3204, and a vertical slider 3205;

[0081] The bottom sides of both ends of the horizontal sliding bracket 3202 of the support housing are horizontally slidably connected to the first guide rail 3101 and the second guide rail 3102 of the support housing. One side of the horizontal sliding bracket 3202 of the support housing is connected to the vertical sliding support bracket 3203 of the support housing. The vertical sliding support bracket 3203 of the support housing is provided with a vertical guide rail 3204 and a first driving mechanism. A vertical straight slot is opened on the side of the vertical sliding support bracket 3203 of the support housing. A vertical slider 3205 is slidably connected to the vertical guide rail 3204 of the support housing. The vertical slider 3205 is connected to the support housing 3201 through the vertical straight slot via a connecting shaft. The support housing 3201 is located between the first guide rail 3101 and the second guide rail 3102 of the support housing. A vertical guide rail shaft is provided on the side of the support housing 3201. A vertical guide rail shaft slider is provided on the side of the vertical sliding support bracket 3203 of the support housing. The vertical guide rail shaft and the vertical guide rail shaft slider are vertically slidably connected.

[0082] Preferably, the support moving part 31 can be configured as two sets, and the support moving part 31 is provided with a guide rail, on which the support housing sliding part 32 can slide.

[0083] Preferably, the bottom support movable parts 31 on both sides of the horizontal sliding frame 3202 of the support housing are slidably connected, and the side of the horizontal sliding frame 3202 of the support housing is connected to the vertical sliding support frame 3203 of the support housing.

[0084] Preferably, the vertical slider 3205 can be driven by the first driving mechanism to slide along the vertical guide rail 3204 of the support housing. The vertical slider 3205 passes through the vertical straight slot and is fixedly connected to the support housing 3201. The vertical guide rail shaft of the support housing 3201 can slide up and down along the vertical guide rail shaft when it is raised and lowered.

[0085] Preferably, the rotary shaft drive 4103, the first drive mechanism, the second drive mechanism, the gripper drive mechanism 4107, the gear drive mechanism 5207, and the push rod drive mechanism 5104 can be driven by a motor, a pneumatic cylinder, an electric cylinder, a hydraulic system, or other methods.

[0086] Furthermore, the lifting hook 33 includes a handle slider 3301, a lifting part 3302, a handle slider guide rail 3303, an arc-shaped stop 3305, and a rotating lifting component 3304.

[0087] The handle slider guide rail 3303 is set on the inner wall of the support housing 3201. The handle slider 3301 is vertically slidably connected to the handle slider guide rail 3303. The lower end face of the handle slider 3301 is connected to the lifting part 3302. The support housing 3201 is provided with a second driving mechanism. The second driving mechanism can drive the rotating lifting member 3304 to rotate. The rotating lifting member 3304 is connected to the handle slider 3301. The rotating lifting member 3304 can drive the handle slider 3301 to rise and fall along the handle slider guide rail 3303. The arc-shaped stop block 3305 is set on the upper side of the inner wall of the support housing 3201.

[0088] Preferably, the rotating lifting component 3304 includes a rotating belt, a rotating wheel, and a second driving mechanism that drives the rotating wheel to rotate. The rotating wheel drives the rotating belt to rotate. One side of the rotating belt is connected to the handle slider 3301. When the rotating belt rotates, it can drive the handle slider 3301 to rise and fall along the handle slider guide rail 3303.

[0089] It should be noted that the rotating lifting component 3304 can also be a combination of a sprocket and a chain; the rotating lifting component 3304 can also be a lifting mechanism that directly drives the handle slider 3301 to lift.

[0090] It should be noted that the handle slider 3301 can also be driven directly by a motor to move up and down along the handle slider guide rail 3303.

[0091] Preferably, the second drive mechanism drives the rotating lifting member 3304, causing the handle slider 3301 to rise and fall along the handle slider guide rail 3303. The handle slider 3301 drives the lifting part 3302 to rise and fall. The lifting part 3302 can hook or grab the upper end of the basket, thereby driving the basket to rise and fall.

[0092] It should be noted that the basket can vertically store multiple sets of racks, and the basket has multiple storage spaces, each of which can store racks.

[0093] Preferably, the lifting part 3302 can be a gripper or a hook; the upper part of the support housing 3201 is also provided with a vision sensing device, which can be a camera or a sensor, and can detect the position of the basket; the arc-shaped stop 3305 has a certain elasticity and can buffer the basket.

[0094] Preferably, the lifting section 3302 will lift the basket into the support housing 3201.

[0095] Furthermore, the rotating gripping assembly 4 includes a rotating gripper 41, a straw gripper 42, and a gripping support shaft 43.

[0096] The two ends of the gripping support shaft 43 are slidably connected to the inside of the operating chamber 1, and the suction gripper 42 and the gripping support shaft 43 are slidably connected to the two sides of the gripping support shaft 43 respectively.

[0097] Furthermore, the rotating gripper 41 includes a gripper support transverse slide plate 4101, a vertical travel plate 4102, a rotating shaft drive 4103, a rotating shaft 4104, a gripper holder 4105, a gripper 4106, and a gripper drive mechanism 4107.

[0098] The gripper support horizontal slide plate 4101 is slidably connected to the side of the gripping support shaft 43, and the vertical stroke plate 4102 is vertically slidably connected to the side of the gripper support horizontal slide plate 4101. The lower end of the vertical stroke plate 4102 is connected to the rotating shaft drive 4103. The rotating shaft drive 4103 is connected to one end of the rotating shaft 4104, and the other end of the rotating shaft 4104 is connected to the gripper frame 4105. The gripper frame 4105 is provided with a gripper drive mechanism 4107, which drives the gripper 4106 to clamp the biological board frame.

[0099] It should be noted that the gripper support horizontal slide plate 4101 is laterally slidably connected to the gripping support shaft 43, and the vertical stroke plate 4102 is vertically slidably connected to the other side of the gripper support horizontal slide plate 4101 under the drive of the motor. The lower end of the vertical stroke plate 4102 is connected to the rotating shaft drive component 4103, which can drive the rotating shaft 4104 to rotate, achieving 360-degree rotation. The rotating shaft 4104 can drive the gripper frame 4105 and the gripper 4106 to rotate, and the gripper drive mechanism 4107 drives the gripper 4106 to grip the frame.

[0100] Furthermore, the straw gripper 42 includes a straw support shaft 4201, a straw vertical slide plate 4202, a straw support block 4203, a straw 4204, and a liquid nitrogen cylinder 4205.

[0101] The straw support shaft 4201 is slidably connected to the other side of the gripping support shaft 43. The straw vertical slide plate 4202 is vertically slidably connected to the straw support shaft 4201. The straw support block 4203 is connected to the straw vertical slide plate 4202. The straw support block 4203 is connected to the straw 4204. A liquid nitrogen cylinder 4205 is provided around the straw 4204. The straw 4204 can draw liquid from the cryopreservation tube.

[0102] It should be noted that the straw support shaft 4201 can be slidably connected along the other side of the gripping support shaft 43, and the straw vertical slide plate 4202 can be vertically slidably connected along the other side of the straw support shaft 4201. The straw vertical slide plate 4202 is connected to the straw support block 4203, and the straw support block 4203 drives the straw 4204 to rise and fall. A liquid nitrogen cylinder 4205 is provided around the straw 4204, and liquid nitrogen can be placed inside the liquid nitrogen cylinder 4205. The lower end of the straw 4204 can suck up the cryopreservation tube. A vacuum pump is connected to the straw and can provide positive and negative pressure gas to the straw 4204 to facilitate the sucking up of the cryopreservation tube.

[0103] Furthermore, the shovel assembly 5 includes a shovel 51 and a storage component 52;

[0104] The storage unit 52 is equipped with a shovel 51, which can push the biological board rack in the basket out through the board rack storage channel, and the storage unit 52 can push the biological board rack into the basket through the board rack storage channel.

[0105] Furthermore, the storage component 52 includes a shovel plate 5201, a sliding push plate 5202, a push block 5203, a sliding push plate support plate 5204, a spur tooth plate 5205, a spur tooth plate meshing gear 5206, a gear drive mechanism 5207, and a support housing 3201.

[0106] The shovel plate 5201 is located at the lower end of the inner side of the plate rack storage channel and is connected to the support housing 3201. The outer side of the support housing 3201 is connected to the sliding push plate support plate 5204. The sliding push plate 5202 is slidably connected to the sliding push plate support plate 5204. The sliding push plate 5202 is sleeved on the outer periphery of the support housing 3201. The sliding push plate 5202 is connected to the push block 5203. A spur plate 5205 is connected to one side of the sliding push plate 5202. The gear drive mechanism 5207 is connected to the spur plate meshing gear 5206. The spur plate meshing gear 5206 is meshed with the spur plate 5205. The sliding push plate support plate 5204 is connected to the gear drive mechanism 5207.

[0107] Preferably, the rotating gripper 41 can grab the plate frame and place it on the shovel plate 5201. Then, the gear drive mechanism 5207 drives the spur gear 5206 to rotate. The spur gear 5206 meshes with the spur plate 5205, thereby driving the spur plate 5205 and the sliding push plate 5202 to move. The sliding push plate 5202 will drive the push block 5203 to move. The push block 5203 pushes the plate frame into the basket. After the plate frame is stored, the push block 5203 retracts.

[0108] Furthermore, the scooping component 51 includes a push rod 5101, a push rod toothed plate 5102, a push rod toothed plate support shaft 5103, and a push rod drive mechanism 5104.

[0109] The push rod spur plate support shaft 5103 is fixedly supported and connected to the sliding push plate support plate 5204. The push rod spur plate support shaft 5103 is located at the end away from the push block 5203. The push rod spur plate 5102 is slidably connected to the push rod spur plate support shaft 5103. The front end of the push rod spur plate 5102 is connected to the push rod 5101. The upper end of the push rod spur plate 5102 is meshed with the push rod drive mechanism 5104. The push rod spur plate meshing gear can drive the push rod drive mechanism 5104.

[0110] It should be noted that the push rod drive mechanism 5104 rotates the push rod gear, which meshes with the push rod spur plate 5102, thereby driving the push rod spur plate 5102 to move. The push rod spur plate 5102 slides along the push rod spur plate support shaft 5103, which drives the push rod 5101 forward. The push rod 5101 pushes the plate frame out of the basket, causing the plate frame to fall onto the shovel plate 5201, which also facilitates the rotation gripping component 4 to grip or pick up the pipe.

[0111] It should be noted that when the basket is inside the support housing 3201, the push rod 5101 can scoop up the rack through the storage channel; the push block 5203 can also be stored in the rack through the storage channel. The basket can be raised or lowered by the lifting hook 33, so that the rack or storage space on the basket can be in the position of the storage channel, which facilitates the storage and retrieval of each layer of basket.

[0112] Furthermore, the cover opening assembly 6 includes a cover opening support shaft 601, a drive lifting mechanism 602, a telescopic rod 603, a support rod 604, a hook part 605, and a guide rod 606.

[0113] The cover opening support shaft 601 is slidably connected to the inside of the operating cabin 1. The drive lifting mechanism 602 is mounted on the cover opening support shaft 601. The upper end of the telescopic rod 603 is connected to the drive lifting mechanism 602, and the lower end of the telescopic rod 603 is connected to the support rod 604. Both ends of the support rod 604 are connected to the hook part 605, and the guide rod 606 is connected to the support rod 604.

[0114] Preferably, the seventh driving component 701 and the driving lifting mechanism 602 can be a motor, a cylinder, or other driving lifting mechanism;

[0115] Preferably, the drive lifting mechanism 602 can drive the telescopic rod 603 to lift and lower, and the telescopic rod drives the support rod 604 to lift and lower. The support rod 604 is provided with hook parts 605 on both sides. The hook parts 605 can hook the heat insulation cover on the upper surface of the storage compartment 2, and the heat insulation cover can close the storage opening.

[0116] Furthermore, it also includes a lifting mechanism 7, which can lift the transfer tank and dock it with the operating cabin 1. The operating cabin 1 has a transfer tank passage opening.

[0117] Preferably, the operating compartment 1 is also equipped with a can lid storage mechanism, which can support the can lid of the transfer tank and can hold can lids of different sizes.

[0118] Furthermore, the lifting mechanism 7 includes a seventh drive component 701, a seventh guide rail 702, a seventh lifting frame 703, and a series conveyor belt 704.

[0119] The seventh lifting frame 703 is vertically slidably connected to the seventh guide rail 702. The upper end of the seventh lifting frame 703 can be used to place the intermediate tank. The seventh driving component 701 can drive the seventh lifting frame 703 to rise and fall along the seventh guide rail 702. The series conveyor belt 704 is set on the upper end of the seventh guide rail 702.

[0120] Preferably, the seventh drive unit 701 can drive the seventh lifting frame 703 to move vertically along the seventh guide rail 702. The upper end of the seventh lifting frame 703 can be used to place the intermediate tank. The rotating gripping component 4 can move the channel cover on the intermediate tank channel opening to the side to facilitate docking of the intermediate tank with the operating cabin 1.

[0121] Preferably, the tandem conveyor belt 704 can connect multiple storage devices in series. The tandem conveyor belt 704 can transport the transfer tank to multiple storage devices or other devices, which greatly saves manpower.

[0122] Furthermore, the operating compartment 1 also includes an identification and storage component 8 and a rotating cleaning component 9. The identification and storage component 8 can identify the barcode of the sample or shelf, and the rotating cleaning component 9 can scan the sample or shelf.

[0123] Preferably, the identification component 8 can scan and identify the labels on the rack or sample tube, and the cleaning component 9 can clean the frost on the labels on the rack or sample tube by rotating it, so as to avoid the phenomenon of being unable to identify.

[0124] Furthermore, storage compartment 2 is equipped with a basket frame to support the basket. Storage compartment 2 is for low-temperature storage, which can ensure the activity of the sample.

[0125] In summary, this invention allows the opening assembly 6 to open the corresponding insulation cover, and the lifting hook 33 to grab or hook the basket in the storage compartment 2, raising the basket to the shelf storage channel position. Then, the shovel 51 pushes the shelf out of the basket at the shelf storage channel position, and the rotating gripping assembly 4 grabs the pushed-out shelf for the next operation. The lifting hook 33 ensures that each shelf in the basket corresponds to the shelf storage channel position. The storage component 52 places the shelf into the basket's storage slot. The rotating gripping assembly 4 can also pick out sample tubes from the shelf, and the rotating jaw 41 can rotate 360 ​​degrees. The top cover of the plate rack or transfer tank can be opened, avoiding the situation where the rotating gripper 41 cannot contact the plate rack or top cover. The lifting mechanism 7 can lift the transfer tank and dock it with the operating chamber 1. The rotating gripping component 4 can open the top cover of the intermediate tank and store the cryopreservation tubes or plate racks inside into the basket through the shovel assembly 5 and the lifting well assembly 3, thereby placing the samples into the storage chamber 2 for freezing. The cryopreservation tubes and plate racks must be scanned by the identification entry component 8 when entering and leaving the storage. Before scanning and identification, the frost on the labels of the plate racks or cryopreservation tubes can be cleaned to prevent the inability to scan. This device realizes automated operation and greatly improves work efficiency.

[0126] It is important to note that the constructions and arrangements of this application shown in several different exemplary embodiments are merely illustrative. Although only a few embodiments are described in detail in this disclosure, those who consult this disclosure will readily understand that many modifications are possible (e.g., changes in the size, dimensions, structure, shape, and proportions of various elements, as well as parameter values ​​(e.g., temperature, pressure, etc.), mounting arrangements, use of materials, color, orientation, etc.) without substantially departing from the novel teachings and advantages of the subject matter described in this application). For example, an element shown as integrally formed may be composed of multiple parts or elements, the position of elements may be inverted or otherwise altered, and the nature or number or position of discrete elements may be changed or altered. Therefore, all such modifications are intended to be included within the scope of the invention. The order or sequence of any process or method steps may be changed or rearranged according to alternative embodiments. In the claims, any "device plus function" clause is intended to cover the structure described herein that performs the function, and not only structurally equivalent but also equivalent in structure. Other substitutions, modifications, alterations, and omissions may be made in the design, operation, and arrangement of the exemplary embodiments without departing from the scope of the invention. Therefore, the present invention is not limited to the specific embodiments, but extends to various modifications that still fall within the scope of the appended claims.

[0127] Furthermore, in order to provide a concise description of exemplary embodiments, not all features of actual embodiments (i.e., those features that are not relevant to the best mode of carrying out the invention as currently considered, or those features that are not relevant to implementing the invention) may be omitted.

[0128] It should be understood that numerous specific implementation decisions can be made during the development of any practical implementation, such as in any engineering or design project. Such development efforts may be complex and time-consuming, but for those skilled in the art who benefit from this disclosure, the development effort will be a routine work of design, manufacturing, and production without requiring much experimentation.

[0129] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit it. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, and all such modifications or substitutions should be covered within the scope of the claims of the present invention.

Claims

1. A sample cryogenic storage system, characterized in that: It includes an operating compartment and a storage compartment; the operating compartment is located above the storage compartment and can perform storage and retrieval operations on the samples in the storage compartment. The upper surface of the storage compartment has multiple storage ports; The operating cabin is equipped with a lifting well assembly, which is movably installed within the operating cabin; the lifting well assembly can be moved to the corresponding storage ports to lift the baskets inside the storage cabin. The operating cabin is also equipped with a rotating gripping component, which can be raised, lowered, and rotated to grip biological plates or biological samples. The rotating gripping assembly is movable within the operating cabin for rotating gripping. The lifting well assembly is surrounded by a shovel plate assembly, and the lifting well assembly has a plate rack storage channel. The shovel plate assembly can scoop up or store the basket through the plate rack storage channel. The operating compartment is also equipped with a cover opening component, which can move and grasp the heat-insulating cover on the storage port. The lifting well assembly includes a supporting movable component, a supporting housing sliding component, and a lifting hook component; The supporting movable component is slidably connected to the operating cabin, and the supporting housing sliding component is slidably connected to the supporting movable component vertically or laterally. A lifting hook is provided inside the supporting housing sliding component, and the lifting hook can lift the basket in the storage cabin through the storage port. The supporting housing sliding component includes a supporting housing, a supporting housing horizontal sliding frame, a supporting housing vertical sliding support frame, a supporting housing vertical guide rail, and a vertical slider; The bottom sides of both ends of the horizontal sliding frame of the support housing are horizontally slidably connected to the supporting moving part. One side of the horizontal sliding frame of the support housing is connected to the vertical sliding support frame of the support housing. The vertical sliding support frame of the support housing is provided with a vertical guide rail and a first driving mechanism. A vertical straight slot is opened on the side of the vertical sliding support frame of the support housing. The vertical slider is slidably connected to the vertical guide rail of the support housing. The vertical slider is connected to the support housing through the vertical straight slot via a connecting shaft. The support housing is located between the first guide rail and the second guide rail of the support housing. A vertical guide rail shaft is provided on the side of the support housing. A vertical guide rail shaft slider is provided on the side of the vertical sliding support frame of the support housing. The vertical guide rail shaft and the vertical guide rail shaft slider are vertically slidably connected. Driven by the first drive mechanism, the vertical slider can slide along the vertical guide rail of the support housing. The vertical slider passes through the vertical straight slot and is fixedly connected to the support housing. When the vertical guide rail shaft of the support housing is raised and lowered, the slider can slide up and down along the vertical guide rail shaft. The lifting hook includes a handle slider, a lifting part, a handle slider guide rail, an arc-shaped stop, and a rotating lifting component; The handle slider guide rail is disposed on the inner wall of the support housing. The handle slider is vertically slidably connected to the handle slider guide rail. The lower end face of the handle slider is connected to the lifting part. A second driving mechanism is disposed on the support housing. The second driving mechanism can drive the rotating lifting component to rotate. The rotating lifting component is connected to the handle slider. The rotating lifting component can drive the handle slider to rise and fall along the handle slider guide rail. The arc-shaped stop block is disposed on the upper side of the inner wall of the support housing. The rotating lifting component includes a rotating belt, a rotating wheel, and a second drive mechanism that drives the rotating wheel to rotate. The rotating wheel drives the rotating belt to rotate. One side of the rotating belt is connected to the handle slider. When the rotating belt rotates, it can drive the handle slider to rise and fall along the handle slider guide rail.

2. The sample low-temperature storage system as described in claim 1, characterized in that: The rotating gripping assembly includes a rotating gripper, a straw gripper, and a gripping support shaft; Both ends of the gripping support shaft are slidably connected to the inside of the operating cabin, and the suction tube gripper and the gripping support shaft are slidably connected to both sides of the gripping support shaft, respectively.

3. The sample low-temperature storage system as described in claim 2, characterized in that: The rotating gripper includes a gripper support transverse slide plate, a vertical travel plate, a rotating shaft drive, a rotating shaft, a gripper frame, a gripper, and a gripper drive mechanism. The gripper supports the horizontal sliding plate and is slidably connected to the side of the gripping support shaft. The vertical travel plate is vertically slidably connected to the side of the gripper supports the horizontal sliding plate. The lower end of the vertical travel plate is connected to the rotating shaft drive component. The rotating shaft drive component is connected to one end of the rotating shaft, and the other end of the rotating shaft is connected to the gripper frame. A gripper drive mechanism is provided inside the gripper frame, and the gripper drive mechanism drives the gripper to clamp the bio-board frame.

4. The sample cryogenic storage system as described in claim 2, characterized in that: The straw gripper includes a straw support shaft, a straw vertical sliding plate, a straw support block, a straw, and a liquid nitrogen cylinder; The straw support shaft is slidably connected to the other side of the gripping support shaft, the straw vertical slide plate is vertically slidably connected to the straw support shaft, the straw support block is connected to the straw vertical slide plate, the straw support block is connected to the straw, and a liquid nitrogen cylinder is provided around the straw. The straw can suck up cryopreservation tubes.

5. The sample cryogenic storage system as described in claim 1, characterized in that: The shovel assembly includes a shovel and a storage component; The storage device is equipped with a shovel, which can push the biological board rack in the basket out through the board rack storage channel, and the storage device can push the biological board rack into the basket through the board rack storage channel.

6. The sample cryogenic storage system as described in claim 5, characterized in that: The storage component includes a shovel plate, a sliding push plate, a push block, a sliding push plate support plate, a spur tooth plate, a spur tooth plate meshing gear, a gear drive mechanism, and a support housing; The shovel plate is disposed at the lower inner side of the plate storage channel and is connected to the support housing. The outer side of the support housing is connected to the sliding push plate support plate. The sliding push plate is slidably connected to the sliding push plate support plate. The sliding push plate is sleeved on the outer periphery of the support housing and is connected to the push block. A spur tooth plate is connected to one side of the sliding push plate. The gear drive mechanism is connected to the meshing gear of the spur tooth plate. The meshing gear of the spur tooth plate is meshed with the spur tooth plate. The sliding push plate support plate is connected to the gear drive mechanism.

7. The sample cryogenic storage system as described in claim 6, characterized in that: The scooping component includes a push rod, a push rod toothed plate, a push rod toothed plate support shaft, and a push rod drive mechanism; The push rod spur gear support shaft is connected to the sliding push plate support plate. The push rod spur gear support shaft is located at the end away from the push block. The push rod spur gear is slidably connected to the push rod spur gear support shaft. The front end of the push rod spur gear is connected to the push rod. The upper end of the push rod spur gear is meshed with the push rod drive mechanism. The push rod spur gear meshing gear can drive the push rod drive mechanism.

8. The sample cryogenic storage system as described in claim 1, characterized in that: The opening assembly includes an opening support shaft, a drive lifting mechanism, a telescopic rod, a support rod, a hook part, and a guide rod; The cover-opening support shaft is slidably connected to the inside of the operating cabin. The drive lifting mechanism is mounted on the cover-opening support shaft. The upper end of the telescopic rod is connected to the drive lifting mechanism. The lower end of the telescopic rod is connected to the support rod. Both ends of the support rod are connected to the hook portion. The guide rod is connected to the support rod.

9. The sample cryogenic storage system as described in claim 1, characterized in that: It also includes a lifting mechanism, which can lift the transfer tank to dock with the operating cabin, and the operating cabin has a transfer tank passage opening.

10. The sample cryogenic storage system as described in claim 9, characterized in that: The lifting mechanism includes a seventh drive component, a seventh guide rail, a seventh lifting frame, and a series of conveyor belts; The seventh lifting frame is vertically slidably connected to the seventh guide rail. The upper end face of the seventh lifting frame can be used to place the intermediate tank. The seventh driving component can drive the seventh lifting frame to move up and down along the seventh guide rail. The series conveyor belt is set on the upper end face of the seventh guide rail.

11. The sample cryogenic storage system as described in claim 1, characterized in that: The operating cabin also includes an identification and warehousing component and a rotating cleaning component. The identification and warehousing component can identify the barcode of the sample or shelf, and the rotating cleaning component can scan the sample or shelf.

Citation Information

Patent Citations

  • Novel sample storage system and method

    CN112303986A