An insecticidal and bactericidal composition and its application

Abstract

The present invention belongs to the field of pesticides and relates to an insecticidal and bactericidal composition with a synergistic effect. The composition is a multi-active component of component A and component B. The active component A is selected from insecticide I-72, and the active component B is selected from one or two of the bactericides; the weight ratio of the active components is 99:1 - 1:99. Compound I-72 has the following structure: The active component B is selected from one or two of the strobilurins, triazoles, pyrroles, amides, benzimidazoles, substituted benzenes, dithiocarbamates, organosulfurs, oxazoles bactericides. The composition of the present invention has the obvious advantage of synergism, and at the same time can control the diseases and insect pests of various crops.

Description

Technical Field

[0001] The present invention belongs to the field of pesticides and relates to an insecticidal and bactericidal composition and its application. Background Art

[0002] Chinese Patent CN112457288 A discloses a piperic acid derivative and its application. Among them, compound I-72 has contact and stomach toxicity activities, good conduction activity, and can be used to control various pests such as Lepidoptera, Hemiptera, Thysanoptera, Coleoptera, etc. This compound has a novel structure, a broad insecticidal spectrum, high activity, and no cross-resistance with other insecticides, and is expected to become an environmentally friendly agent for controlling resistant pests.

[0003] The methoxyacrylate fungicides have high activity, low dosage, and good therapeutic and protective effects on various plant diseases caused by Oomycetes, Mycobacteria, Ascomycetes, Basidiomycetes, and Deuteromycetes. They are widely used in cereals, rice, fruit trees, vegetables, and cash crops, etc., and have good environmental compatibility.

[0004] Pyrrole fungicides play a disease-preventing role by inhibiting the synthesis of amino acids in the bacteria. The active ingredient does not move in the soil, so a stable and persistent protection circle is formed around it. It is mainly used for the treatment of crop seed-borne diseases.

[0005] Triazole fungicides are active against pathogens of Ascomycotina, Basidiomycotina, and Deuteromycotina. Their mechanism of action is to affect the biosynthesis of sterols, which damages the function of the cell membrane of the bacteria.

[0006] Amide fungicides are effective against soil fungi such as Puccinia monoica and Puccinia graminis in wheat rust pathogens, Ustilago nuda and Tilletia foetida in black rust pathogens, and Rhizoctonia solani in crop root rot and wilt diseases in tomatoes, eggplants, cucumbers, etc., and are particularly effective against Basidiomycetes.

[0007] Through literature retrieval, no technical solutions of multi-component insecticidal and fungicidal compositions containing compound I-72 have been specifically disclosed. Summary of the Invention

[0008] The purpose of the present invention is to provide an insecticidal and bactericidal composition and its application.

[0009] To achieve the above purpose, the technical solution adopted by the present invention is as follows:

[0010] An insecticidal and bactericidal composition, the composition is composed of active components A and B. Among them, active component A is a piperic acid derivative compound with the following structure (i.e., compound I-72), and active component B is selected from one or two of the fungicides;

[0011] The piperic acid derivative compound has the following structure:

[0012]

[0013] The active ingredient B fungicide is selected from one or two of methoxyacrylates, triazoles, pyrroles, amides, benzimidazoles, substituted benzenes, dithiocarbamates, organic sulfurs, and oxazoles; the weight ratio of the active ingredients is 99:1 - 1:99.

[0014] Component A in the composition is selected from the above - structured piperic acid derivative compounds; the active ingredient B is selected from one or two of azoxystrobin, pyraoxystrobin, pyraclostrobin, enestroburin, enestroburin amine, pyraclostrobin, caryofect, triadimefon, difenoconazole, tebuconazole, hexaconazole, ipconazole, epoxiconazole, fludioxonil, metalaxyl, metalaxyl - M, silthiofam, carboxin, fluopicolide, prochloraz, carbendazim, pyridinilan, hymexazol, thiram, mancozeb, copper preparations, and lime sulfur; the weight ratio of the active ingredients is 50:1 - 1:50.

[0015] Component A in the composition is selected from the above - structured piperic acid derivative compounds; the active ingredient B is one or two of enestroburin amine, azoxystrobin, pyraoxystrobin, fludioxonil, tebuconazole, difenoconazole, metalaxyl, metalaxyl - M, pyraclostrobin, caryofect; the preferred weight ratio of the components is 40:1 - 1:20.

[0016] Use of the described composition for controlling agricultural and forestry diseases and pests.

[0017] A method for controlling pests and / or diseases, applying the composition in an effective dose to the growth medium of pests and / or diseases.

[0018] The insecticidal and fungicidal composition of the present invention has good plant compatibility, is suitable for controlling various plant diseases and pests, and can preferably be used as a crop protection composition for plant seed treatment, foliage treatment, or soil treatment.

[0019] The composition of the present invention has good control effects on pathogenic fungi of plants. The following pathogenic fungi are presented by way of example and not limitation: Albugo (white rust) on ornamental plants, vegetables (e.g., A. candida), and sunflowers (e.g., A. tragopogonis); Alternaria (black spot) on vegetables, rape (A. brassicola or A. brassicae), sugar beet (A. tenuis), fruits, rice, soybeans, and potatoes (e.g., A. solani or A. alternata), tomatoes (e.g., A. solani or A. alternata), and wheat; Aphanomyces on sugar beet and vegetables; Ascochyta on cereals and vegetables, such as A. tritici on wheat (Ascochyta leaf blight) and A. hordei on barley; Bipolaris and Drechslera (sexual form Cochliobolus), such as D. maydis or B. zeicola on corn, such as B. sorokiniana on cereals (spot blotch) and B. oryzae on rice and lawns, for example; Blumeria (powdery mildew) on cereals such as wheat or barley; Botrytis cinerea (sexual form: Botryotinia fuckeliana: gray mold) on fruits and berries (e.g., strawberries), vegetables (e.g., lettuce, carrots, celeriac, and cabbages), rape, flowers, grapevines, forest plants, and wheat; Bremia lactucae on lettuce (downy mildew); Ceratocystis (synonym Ophiostoma) on broad-leaved and evergreen trees (rot or wilt), such as C. ulmi on elm trees (Dutch elm disease); Cercospora (Cercospora leaf spot) on corn (e.g., gray leaf spot: C. zeae-maydis), rice, sugar beet (e.g., C. beticola), sugar cane, vegetables, coffee, soybeans (e.g., C. sojina or C. kikuchii), and rice; C. fulvum on tomatoes (tomato leaf mold) and cereals (e.g., C. on wheatCladosporium on herbarum (ear rot); Claviceps purpurea on cereals (ergot disease); Cochliobolus on maize (C. carbonum), cereals (e.g., C. sativus, anamorph: Bipolaris sorokiniana) and rice (e.g., C. miyabeanus, anamorph: B. oryzae) (leaf spot); Colletotrichum on cotton (e.g., C. gossypii), maize (e.g., C. graminicola), berries, potato (e.g., C. coccodes: wilt), bean (e.g., C. lindemuthianum) and soybean (e.g., C. truncatum or C. gloeosporioides) (anthracnose); Corticium, e.g., C. sasakii on rice (sheath blight); Corynespora cassiicola on soybean and ornamental plants (leaf spot); Cycloconium, e.g., C. oleaginum on olive; Cylindrocarpon on fruit trees, grapevines (e.g., C. liriodendri, teleomorph: Neonectria liriodendri: black foot disease) and ornamental plants (e.g., fruit tree canker or grapevine black foot disease, teleomorph: Nectria or Neonectria); Dematophora (teleomorph: Rosellinia) necatrix on soybean (root rot / stem rot); Diaporthe, e.g., D. phaseolorum on soybean (stem canker); Drechslera on maize, cereals such as barley (e.g., D. teres, net blotch) and wheat (e.g., D. tritici-repentis: DTR leaf spot), rice and turf (synonym Helminthosporium, teleomorph: Pyrenophora); caused by Formitiporia (synonym (Phellinus) punctata), F.Esca (vine decline, dieback) on grapevines caused by Phaeoacremonium aleophilum, Phaeomoniella chlamydospora (formerly Phaeoacremnium chlamydosporum), and / or Botryosphaeria obtusa; Elsinoe on pomaceous fruit (E. pyri), berries (E. veneta: anthracnose), and grapevines (E. ampelina: anthracnose); Entyloma oryzae (leaf smut) on rice; Epicoccum on wheat (smut); Erysiphe (powdery mildew) on sugar beet (E. betae), vegetables such as peas (E. pisi), cucurbits such as E. cichoracearum, cabbage, rape (e.g., E. cruciferarum); Eutypa lata (Eutypa canker or dieback, anamorph: Cytosporina lata, synonym Libertella blepharis) on fruit trees, grapevines, and ornamental trees; Exserohilum (synonym Helminthosporium) on maize (e.g., E. turcicum); Fusarium (teleomorph: Gibberella) (wilt, root rot, and stem rot) on various plants, e.g., F. graminearum or F. culmorum (root rot, scab, or silver point) on cereals such as wheat or barley, F. oxysporum on tomatoes, F. solani on soybeans, and F. verticillioides on maize; Gaeumannomyces graminis (take-all) on cereals such as wheat or barley and maize; Gibberella on cereals such as G. zeae and rice (e.g., G. fujikuroi: bakanae disease); Glomerella cingulata on grapevines, pomaceous fruit, and other plants and G. gossypii on cottongossypii); Grainstaining complex on rice; Guignardia bidwellii (black rot) on grapevine; Gymnosporangium on Rosaceae plants and junipers, e.g., G. sabinae on pear (pear rust); Helminthosporium (synonym: Cochliobolus, teleomorph: Pseudocercospora) on maize, cereals and rice; Hemileia, e.g., Hemileia vastatrix on coffee (coffee leaf rust); Isariopsis clavispora (synonym: Cladosporium vitis) on grapevine; Macrophomina phaseolina (synonym: phaseoli) (root rot and stem rot) on soybean and cotton; Microdochium (synonym: Fusarium) nivale (snow mold) on cereals (e.g., wheat or barley); Microsphaera diffusa (powdery mildew) on soybean; Monilinia, e.g., Monilinia laxa, Monilinia fructicola and Monilinia fructigena on stone fruits and other Rosaceae plants (flower rot and twig rot, brown rot); Mycosphaerella on cereals, banana, berries and peanuts, e.g., Mycosphaerella graminicola on wheat (anamorph: Septoria tritici, Septoria leaf blotch) or Mycosphaerella fijiensis on banana (Sigatoka black leaf streak); Peronospora (downy mildew) on cabbage (e.g., Peronospora brassicae), rape (e.g., Peronospora parasitica), alliums (e.g., Peronospora destructor), tobacco (Peronospora tabacina) and soybean (e.g., Peronospora manshurica); Phakopsora pachyrhizi and Phakopsora meibomiae (soybean rust) on soybean; Phialophora, e.g., Phialophora tracheiphila and Phialophora tetraspora on grapevine (e.g.) and Phialophora gregata on soybean (soybean stem canker: stem disease); Phoma lingam (root rot and stem rot) on rape and cabbage and Phoma betae on sugar beetbetae) (root rot, leaf spot and damping-off); Phomopsis on sunflowers, grapevines (e.g., P. viticola on vines and leaf spot) and soybeans (e.g., stem rot: P. phaseoli, sexual form: Diaporthe phaseolorum); Physoderma maydis (brown spot) on corn; Phytophthora (wilt, root rot, leaf rot, fruit rot and stem rot) on various plants such as bell peppers and cucurbitaceous plants (e.g., P. capsici), soybeans (e.g., P. megasperma, synonym P. sojae), potatoes and tomatoes (e.g., P. infestans: late blight) and broad-leaved trees (e.g., P. ramorum: sudden oak death); Plasmodiophora brassicae (clubroot) on cabbages, rape, radishes and other plants; Plasmopara, e.g., P. viticola (downy mildew of grapevine) on grapevines and P. halstedii on sunflowers; Podosphaera (powdery mildew) on Rosaceae plants, hops, pomaceous fruits and berries, e.g., P. leucotricha on apples; Polymyxa on cereals such as barley and wheat (P. graminis) and sugar beets (P. betae) and virus diseases transmitted thereby; Pseudocercosporella herpotrichoides (eyespot, sexual form: Tapesia yallundae) on cereals such as wheat or barley; Pseudoperonospora (downy mildew) on various plants, e.g., P. cubensis on cucurbitaceous plants or P. humili on hops; Pseudopezicula tracheiphila (angular leaf scorch or "soft rot" of grapevine, anamorph: Phialophora); Puccinia (rust) on various plants, e.g., P. triticina (brown rust of wheat) on cereals such as wheat, barley or rye, P. striiformis (yellow rust), P. hordei (barley yellow dwarf leaf rust), P. graminis (black rust) or P.Puccinia recondita (black stem rust of rye), and Puccinia spp. on asparagus such as Puccinia asparagi; Pyrenophora (anamorph: Drechslera) tritici-repentis (tan spot) on wheat or Pyrenophora teres (net blotch) on barley; Pyricularia spp., such as Pyricularia oryzae (sexual form: Magnaporthe grisea, rice blast) on rice and Pyricularia grisea on turf and cereals; Pythium spp. (damping-off) on turf, rice, corn, wheat, cotton, rape, sunflower, soybean, sugar beet, vegetables and various other plants (e.g., Pythium ultimum or Pythium aphanidermatum); Ramularia spp., such as Ramularia collo-cygni (Ramularia leaf spot, physiological leaf spot) on barley and Ramularia beticola on sugar beet; Rhizoctonia spp. on cotton, rice, potato, turf, corn, rape, potato, sugar beet, vegetables and various other plants, such as Rhizoctonia solani (root and stem rot) on soybean, Rhizoctonia solani (sheath blight) on rice or Rhizoctonia cerealis (sharp eyespot) on wheat or barley; Rhizopus stolonifer (black mold, soft rot) on strawberry, carrot, cabbage, grapevine and tomato; Rhynchosporium secalis (leaf spot) on barley, rye and triticale; Sarocladium oryzae and Sarocladium attenuatum (sheath rot) on rice; Sclerotinia spp. (stem rot or southern blight) on vegetables and field crops such as rape, sunflower (e.g., Sclerotinia sclerotiorum) and soybean (e.g., Sclerotinia rolfsii or Sclerotinia sclerotiorum); Septoria spp. on various plants, such as Septoria glycines (brown spot) on soybean, Septoria tritici (Septoria leaf spot) on wheat and Septoria nodorum on cereals.(synonym Stagonospora) nodorum) (stagonospora blotch); Uncinula (synonym Erysiphe) necator) on grapevines (powdery mildew, anamorph: Oidium tuckeri); Setospaeria on maize (e.g., S. turcicum, synonym Helminthosporium turcicum) and turf (leaf spot); Sphacelotheca on maize (e.g., S. reiliana: head smut), sorghum and sugarcane (smut); Sphaerotheca fuliginea on cucurbitaceous plants (powdery mildew); Spongospora subterranea on potatoes (powdery scab) and virus diseases transmitted thereby; Stagonospora on cereals, e.g., S. nodorum on wheat (stagonospora blotch, teleomorph: Leptosphaeria [synonym Phaeosphaeria] nodorum); Synchytrium endobioticum on potatoes (potato wart disease); Taphrina, e.g., T. deformans on peaches (leaf curl) and T. pruni on plums (bladder plum); Thielaviopsis on tobacco, pomaceous fruits, vegetables, soybeans and cotton (black root rot), e.g., T. basicola (synonym Chalara elegans); Tilletia on cereals (bunt or loose smut), e.g., T. tritici on wheat (synonym T. caries, wheat bunt) and T. controversa (dwarf bunt); Typhula incarnata on barley or wheat (grey snow mold); Urocystis, e.g., U. occulta on rye (striped smut); Uromyces on vegetables such as beans (e.g., U. appendiculatus, synonym U. phaseoli) and sugar beets (e.g., U. betae) (rust); Ustilago on cereals (e.g., U. nuda and U. avenae), maize (e.g., U. maydis)on maize (e.g., Ustilago maydis (smut)) and on sugarcane (Ustilago (smut)); on apples (e.g., Venturia inaequalis (scab)) and pears (Venturia (scab)); and on various plants such as fruit trees and ornamental plants, vines, berries, vegetables and field crops (Verticillium (wilt)), e.g., Verticillium dahliae on strawberries, oilseed rape, potatoes and tomatoes.

[0020] The compositions of the present invention are effective against sensitive and resistant species of pests and all or individual developmental stages, including pests of the order Homoptera, such as Acrythosiphon pisum (pea aphid), Adelges spp. (adelgid), Aleurodes proletella (cabbage whitefly), Aleurodicus disperses, Aleurothrixus floccosus (woolly whitefly), Aluacaspis spp., Amrasca bigutella bigutella, Aphrophom spp. (leafhoppers), Aonidiella aurantii (California red scale), Aphisspp. (aphids), Aphis gossypii (cotton aphid), Aphis pomi (apple aphid), Aulacorthum solani (foxglove aphid), Bemisia spp. (whiteflies), Bemisia argentifolii, Bemisia tabaci (sweetpotato whitefly), Brachycolus noxius (Russian aphid), Bmchycorynella asparagi (asparagus aphid), Brevennia rehi, Brevicoryne brassicae (cabbage aphid), Ceroplastes spp. (scales), Ceroplastes rubens (red wax scale), Chionaspis spp. (scales), Chrysomphalus spp. (scales), Coccus spp. (scales), Dysaphis plantaginea (rosy apple aphid), Empoasca spp.)(leafhoppers), Eriosoma lanigerum (woolly apple aphid), Icerya purchasi (cottony cushion scale), Idioscopus nitidulus (mango leafhopper), Laodelphax striatellus (smaller brown planthopper), Lepidosaphes spp., Macrosiphum spp., Macrosiphum euphorbiae (potato aphid), Macrosiphum granarium (English grain aphid), Macrosiphum rosae (rose aphid), Macrosteles quadrilineatus (aster leafhopper), Mahanarva frimbiolata, Metopolophium dirhodum (rose grain aphid), Mictis longicornis, Myzus persicae (green peach aphid), Nephotettix spp. (leafhoppers), Nephotettix cinctipes (green leafhopper), Nilaparvata lugens (brown planthopper), Parlatoria pergandii (chaff scale), Parlatoria ziziphi (ebony scale), Peregrinus maidis (corn delphacid), Philaenus spp. (spittlebugs), Phylloxera vitifoliae (grape phylloxera), Physokermes piceae (spruce bud scale), Planococcus spp. (mealybugs), Pseudococcus spp.)(mealybugs), Pseudococcus brevipes (pineapple mealybug), Quadraspidiotus perniciosus (San Jose scale), Rhapalosiphum spp. (aphids), Rhapalosiphum maida (corn leaf aphid), Rhapalosiphum padi (oat bird-cherry aphid), Saissetia spp. (scales), Saissetia oleae (black scale), Schizaphis graminum (greenbug), Sitobion avenae (English grain aphid), Sogatella furcifera (white-backed planthopper), Therioaphis spp. (aphids), Toumeyella spp. (scales), Toxoptera spp. (aphids), Trialeurodes spp. (whiteflies), Trialeurodes vaporariorum (greenhouse whitefly), Trialeurodes abutiloneus (bandedwing whitefly), Unaspis spp. (scales), Unaspis yanonensis (arrowhead scale) and Zulia entreriana; Coleoptera, such as Acanthoscelides spp. (weevils), Acanthoscelides obtectus (common bean weevil), Agrilus planipennis (emerald ash borer), Agriotes spp. (wireworms), Anoplophora glabripennis (Asian longhorned beetle), Anthonomus spp.)(weevils), boll weevil (Anthonomus grandis), Aphidius spp., Apion spp. (weevils), Apogonia spp. (grubs), Black Turgrass Ataenius (Ataenius spretulus), pygmy mangold beetle (Atomarialinearis), Aulacophore spp., beet root weevil (Bothynoderespunctiventris), Bruchus spp. (weevils), pea weevil (Bruchuspisorum), Cacoesia spp., southern cow pea weevil (Callosobruchus maculatus), dried fruitbeetle (Carpophilus hemipteras), Cassida vittata, Cerosterna spp., Cerotoma spp. (chrysomeids), bean leaf beetle (Cerotoma trifurcata), Ceutorhynchusspp. (weevils), cabbage seedpod weevil (Ceutorhynchus assimilis), cabbage curculio (Ceutorhynchus napi), Chaetocnema spp. (chrysomeids), Colaspis spp.(soil beetle), Conoderus scalaris, Conoderus stigmosus, Conotrachelus nenuphar (plum curculio), Cotinus nitidis (Green June beetle), Crioceris asparagi (asparagus bettle), Cryptolestes ferrugineus (rusty grain beetle), Cryptolestes pusillus (flat grain beetle), Cryptolestes turcicus (Turkish grain beetle), Ctenicera spp. (wireworms), Curculio spp. (weevils), Cyclocephala spp. (grubs), Cylindrocpturus adspersus (sunflower stem weevil), Deporaus marginatus (mango leaf-cutting weevil), Dermestes lardarius (larder beetle), Dermestes maculates (hide beetle), Diabrotica spp. (chrysolemid), Epilachna varivestis (Mexican bean beetle), Faustinus cubae, Hylobius pales (pales weevil), Hypera spp. (weevils), Hypera postica (alfalfa weevil), Hyperodes spp. (Hyperodes weevil), Hypothenemus hampei (coffee berry beetle), Ips spp.)(engraver), Lasioderma serricorne (cigarette beetle), Leptinotarsa decemlineata (Colorado potato beetle), Liogenys fuscus, Liogenys suturalis, Lissorhoptrus oryzophilus (rice water weevil), Lyctus spp. (woodbeetles / powder post beetles), Maecolaspis joliveti, Megascelis spp, Melanotus communis, Meligethes spp., Meligethes aeneus (blossombeetle), Melolontha melolontha (common European cockchafer), Obereabrevis, Oberea linearis, Oryctes rhinoceros (date palmbeetle), Oryzaephilus mercator (merchant grain beetle), Oryzaephilus surinamensis (sawtoothed grain beetle), Otiorhynchus spp. (weevils), Oulema melanopus (cereal leaf beetle), Oulema oryzae, Pantomorus spp. (weevils), Phyllophaga spp. (May / June beetle), Phyllophaga cuyabana, Phyllotreta spp. (chrysomeids), Phynchites spp.) Popillia japonica (Japanese beetle), Prostephanus truncates (larger grain borer), Rhizopertha dominica (lesser grain borer), Rhizotrogus spp. (European chafer), Rhynchophorus spp. (weevils), Scolytus spp. (wood beetle), Shenophorus spp. (Billbug), Sitona lineatus (pea leaf weevil), Sitophilus spp. (grain weevil), Sitophilus granarius (granary weevil), Sitophilus oryzae (rice weevil), Stegobium paniceum (drugstore beetle), Tribolium spp. (flour beetle), Tribolium castaneum (red flour beetle), Tribolium confusum (confused flour beetle), Trogoderma variabile (warehouse beetle), and Zabrus tenebioides. Diptera, such as Aedes spp. (mosquitoes), Agromyza frontella (alfalfa blotch leafminer), Agromyza spp. (leaf miner flies), Anastrepha spp. (fruit flies), Anastrepha suspensa (Caribbean fruit fly), Anopheles spp. (mosquitoes), Bactrocera spp.)(fruit flies), Bactrocera cucurbitae (melon fly), Bactrocera dorsalis (oriental fruit fly), Ceratitis spp. (fruit flies), Ceratitis capitata (Mediterranea fruit fly), Chrysops spp. (deer flies), Cochliomyia spp. (screwworms), Contarinia spp. (Gall midges), Culex spp. (mosquitoes), Dasineura spp. (gall midges), Dasineura brassicae (cabbage gall midge), Delia spp., Delia platura (seedcorn maggot), Drosophila spp. (vinegar flies), Fannia spp. (filth flies), Fannia canicularis (little house fly), Fannia scalaris (latrine fly), Gasterophilus intestinalis (horse bot fly), Gracillia perseae, Haematobia irritans (horn fly), Hylemyia spp. (root maggots), Hypoderma lineatum (common cattle grub), Liriomyza spp. (leafminer flies), Liriomyza brassica (serpentine leafminer), Melophagus ovinus (sheep ked), Musca spp.)(muscidflies), Musca autumnalis (face fly), Musca domestica (house fly), Oestrus ovis (sheep bot fly), Oscinella frit (frit fly), Pegomya betae (beet leafminer), Phorbia spp., Psila rosae (carrotrust fly), Rhagoletis cerasi (cherry fruit fly), Rhagoletis pomonella (apple maggot), Sitodiplosis mosellana (orange wheat blossom midge), Stomoxys calcitrans (stable fly), Tabanus spp. (horse flies) and Tipula spp. (crane flies). Hemiptera, such as Acrosternum hilare (green stink bug), Blissus leucopterus (chinchbug), Calocoris norvegicus (potato mirid), Cimex hemipterus (tropical bed bug), Cimex lectularius (bed bug), Dagbertus fasciatus, Dichelops furcatus, Dysdercus suturellus (cotton stainer), Edessa meditabunda, Eurygaster maura (cereal bug), Euschistus heros, Euschistus servus (brown stink bug), Helopeltis antonii, Helopeltis theivora (tea blight plantbug), Lagynotomus spp.)(stinkbugs), Leptocorisa oratorius (rice ear bug), Leptocorisa varicornis, Lygus spp. (plant bug), Lygus hesperus (western tarnished plantbug), Maconellicoccus hirsutus, Neurocolpus longirostris, Nezara viridula (southern green stink bug), Paratrioza cockerelli, Phytocoris spp. (plant bug), Phytocoris califomicus, Phytocorisrelativus, Piezodoms guildingi, Poecilocapsus lineatus (fourlinedplant bug), Psallus vaccinicola, Pseudacysta perseae, Scaptocoris castanea, and Triatoma spp. (bloodsucking conenose bug / kissing bug). Thysanoptera, such as Frankliniella fusca (tobacco thrips), Frankliniella occidentalis (western flower thrips), Frankliniella shultzei, Frankliniella williamsi (corn thrips), Heliothrips haemorrhaidalis (greenhouse thrips), Riphiphorothrips cruentatus, Scirtothrips spp., Scirtothrips citri (citrus thrips), Scirtothrips dorsalis (yellow tea thrips), Taeniothrips rhopalantennalis, and Thrips spp..

[0021] The present invention has the following advantages:

[0022] The insecticidal and fungicidal composition of the present invention has a synergistic effect, can achieve the effect of simultaneously controlling pests and diseases, reduce the drug use cost, is applicable to controlling various diseases and pests, and protects the ecological environment. Specifically:

[0023] First, the composition shows an obvious synergistic effect within a certain ratio range, significantly improves the control effect on various pests, thereby can reduce the amount of pesticides used, reduce the drug use cost of farmers, and reduce the impact on the environment; second, it can simultaneously control the diseases and pests occurring in the same period, providing an extremely convenient and effective control means for users.

[0024] Specific implementation methods of bioassay

[0025] The following specific examples are used to further illustrate the present invention in detail, but the present invention is by no means limited to these examples. The percentage content or ratio of each component in the examples is based on weight. The active components in each formula are calculated based on the effective content, and each substance in the composition can be obtained by conventional methods.

[0026] Indoor bioactivity determination

[0027] Example 1

[0028] Determination of the combined toxicity of the composition containing compound I-72 against Agrotis ypsilon.

[0029] Test target: 3rd instar larvae of Agrotis ypsilon (Rottemberg), sensitive strain reared indoors.

[0030] Test conditions: Temperature: 24 - 26 °C, Humidity: RH 60%, Illumination: L:D = 14:10

[0031] Preparation of the liquid medicine: According to different test requirements, accurately weigh the test samples respectively with an electronic analytical balance. The technical drug is dissolved in acetone, and then diluted with 0.1% Tween 80 water into a series of liquid medicines with a certain concentration gradient according to the test design dose.

[0032] Test method: The activity against Agrotis ypsilon was determined by the immersion method. Select 3rd instar early-stage larvae of Agrotis ypsilon, immerse the target in the liquid medicine for 10 s and then take it out, blot the excess liquid medicine with filter paper. Each treatment has 4 replicates, and 12 insects are immersed in each replicate. A treatment without the medicine is set as the blank control.

[0033] Transfer the test insects to a multi-well culture plate with fresh cabbage leaves and place it in the observation chamber. The temperature, humidity, and light in the observation chamber can be adjusted as needed. After 72 hours, investigate the number of dead and live insects. Calculate the corrected mortality rate using the Abbott formula and perform statistical analysis using DPS data processing software to obtain the virulence regression equations and LC50 values of each tested single agent and each different ratio mixture. Then, use the Sun y-p method to calculate the co-toxicity coefficient of each ratio and evaluate the mixing effect. The test results are shown in Table 1.

[0034] The co-toxicity coefficient (CTC value) of the mixture is calculated according to the following formula:

[0035]

[0036] Where: ATI - measured virulence index of the mixture; S - LC50 of the standard agent; M - LC50 of the mixture.

[0037] TTI = TIA × PA + TIB × PB

[0038] Where: TTI - theoretical virulence index of the mixture; TIA - virulence index of agent A; PA - percentage content of agent A in the mixture; TIB - virulence index of agent B; PB - percentage content of agent B in the mixture.

[0039]

[0040] Where: CTC - co-toxicity coefficient; ATI - measured virulence index of the mixture; TTI - theoretical virulence index of the mixture.

[0041] When the co-toxicity coefficient (CTC) of the mixture ≥ 120, it shows a synergistic effect; when CTC ≤ 80, it shows an antagonistic effect; when 80 < CTC < 120, it shows an additive effect.

[0042] Table 1 Results of joint toxicity determination of the composition containing compound I-72 against Agrotis ypsilon

[0043]

[0044]

[0045] As can be seen from the table (Table 1), the mixture of compound I-72 and enestroburin and fludioxonil shows an obvious synergistic effect on the 3rd instar larvae of Agrotis ypsilon at the ratios of 40:1 to 1:20.

[0046] Example 2

[0047] Joint toxicity determination of the composition containing compound I-72 against Agrotis ypsilon.

[0048] Test target: 3rd instar larvae of the black cutworm [Agrotis ypsilon (Rottemberg)], a sensitive strain reared indoors.

[0049] Test conditions: Temperature: 24 - 26 °C, Humidity: RH 60%, Lighting: L:D = 14:10

[0050] Preparation of the liquid medicine: According to different test requirements, accurately weigh the test samples separately with an electronic analytical balance. The technical material is dissolved in acetone and then diluted with 0.1% Tween 80 water into a series of liquid medicines with certain concentration gradients according to the test design dosage.

[0051] Test method: The immersion method was used to determine the activity against the black cutworm. Select 3rd instar early-stage black cutworm larvae, immerse the target in the liquid medicine for 10 s and then take it out, blot the excess liquid medicine with filter paper. Each treatment has 4 replicates, with 12 insects immersed in each replicate, and a treatment without the medicine is set as the blank control.

[0052] Transfer the test insects to a multi-well culture plate with fresh cabbage leaves and place them in the observation room. The temperature, humidity, and lighting in the observation room can be adjusted as needed. After 72 hours, investigate the number of dead and live insects. Calculate the corrected mortality rate using the Abbott formula, perform statistical analysis with DPS data processing software, obtain the toxicity regression equations and LC50 values of each test single agent and each different mixture ratio, and then calculate the co-toxicity coefficient of each mixture ratio using the Sun Yunpei (Sun y-p) method to evaluate the mixing effect. The test results are shown in Table 2.

[0053] The co-toxicity coefficient (CTC value) of the mixture is calculated according to the following formula:

[0054]

[0055] Where: ATI - the measured toxicity index of the mixture; S - the LC50 of the standard medicine; M - the LC50 of the mixture.

[0056] TTI = TIA × PA + TIB × PB

[0057] Where: TTI - the theoretical toxicity index of the mixture; TIA - the toxicity index of agent A; PA - the percentage content of agent A in the mixture; TIB - the toxicity index of agent B; PB - the percentage content of agent B in the mixture.

[0058]

[0059] Where: CTC - the co-toxicity coefficient; ATI - the measured toxicity index of the mixture; TTI - the theoretical toxicity index of the mixture.

[0060] In the formula, the co-toxicity coefficient (CTC) of the mixture ≥ 120 indicates a synergistic effect; CTC ≤ 80 indicates an antagonistic effect; 80 < CTC < 120 indicates an additive effect.

[0061] Table 2 Results of joint toxicity determination of the composition containing compound I-72 against Agrotis ypsilon

[0062]

[0063] It can be seen from the table (Table 2) that the mixture of compound I-72 and metalaxyl-M shows an obvious synergistic effect on the 3rd instar larvae of Agrotis ypsilon at the ratio of 40:1 to 1:20.

[0064] Example 3

[0065] Joint toxicity determination of the composition containing compound I-72 against Holotrichia diomphalia Bates.

[0066] Test target: The early 2nd instar of Holotrichia diomphalia Bates

[0067] Test conditions: Temperature: 24 - 26 °C, Humidity: RH 60%, Illumination: L:D = 14:10

[0068] Preparation of the liquid medicine: According to different test requirements, accurately weigh the test samples respectively with an electronic analytical balance. The technical material is dissolved in acetone, and then diluted with 0.1% Tween 80 water into a series of liquid medicines with a certain concentration gradient according to the test design dose.

[0069] Test method: The activity against Holotrichia diomphalia Bates was determined by the method of dipping insects. Select the early 2nd instar of Holotrichia diomphalia Bates, immerse the target in the liquid medicine for 10 s and then take it out, absorb the excess liquid medicine with filter paper. Each treatment has 4 replicates, and 12 insects are dipped in each replicate. A treatment without the medicine is set as the blank control.

[0070] Transfer the test insects to a multi-well culture plate with fresh potato pieces, place them in the observation room, and the temperature, humidity and illumination in the observation room can be adjusted as needed. After 72 hours, investigate the number of dead and live insects. Calculate the corrected mortality rate with the Abbott formula, perform statistical analysis with DPS data processing software, obtain the toxicity regression equation and LC50 value of each test single agent and each mixture with different ratios, and then calculate the co-toxicity coefficient of each ratio by the Sun y-p method to evaluate the mixing effect. The test results are shown in Table 3.

[0071] The co-toxicity coefficient (CTC value) of the mixture is calculated according to the following formula:

[0072]

[0073] In the formula: ATI - the measured toxicity index of the mixture; S - the LC50 of the standard medicine; M - the LC50 of the mixture.

[0074] TTI = TIA × PA + TIB × PB

[0075] Where: TTI - theoretical toxicity index of the mixture; TIA - toxicity index of pesticide A; PA - percentage content of pesticide A in the mixture; TIB - toxicity index of pesticide B; PB - percentage content of pesticide B in the mixture.

[0076]

[0077] Where: CTC - co-toxicity coefficient; ATI - measured toxicity index of the mixture; TTI - theoretical toxicity index of the mixture.

[0078] Where the co-toxicity coefficient (CTC) of the mixture ≥ 120 indicates a synergistic effect; CTC ≤ 80 indicates an antagonistic effect; 80 < CTC < 120 indicates an additive effect.

[0079] Table 3 Results of joint toxicity determination of the composition containing compound I-72 against white grubs

[0080]

[0081]

[0082] It can be seen from the table (Table 3) that the mixture of compound I-72 and difenoconazole, tebuconazole and azoxystrobin shows a synergistic effect on the newly molted 2nd instar larvae of white grubs at the ratio of 40:1 to 1:20.

[0083] Example 4

[0084] Control effect of the composition containing compound I-72 against Bemisia tabaci.

[0085] Test target: Adults of Bemisia tabaci (Gennadius), sensitive strain reared indoors.

[0086] Preparation of liquid medicine: According to different test requirements, accurately weigh the test samples with an electronic analytical balance respectively. The technical materials are dissolved in acetone and then diluted into a series of liquid medicines with certain concentration gradients according to the test design dose with 0.1% Tween 80 water.

[0087] Test method: Spray method is adopted. Select healthy cotton seedlings (with 2 cotyledons), and then spray the prepared liquid medicine on the whole plant with an airbrush manual sprayer in the order of low dose to high dose according to the test design. After natural air drying, cover with a glass cover. After the test insects are stable, introduce about 40 test insects, and remove the unhealthy test insects on the surface. The test is set with 4 replicates, and a blank control is set. The results are investigated after 72 hours, and the mortality rate is calculated.

[0088] The corrected mortality was calculated using the Abbott formula, and statistical analysis was performed using DPS data processing software to obtain the toxicity regression equations and LC50 values of each tested single agent and each different ratio mixture. Then, the co-toxicity coefficient of each ratio was calculated using the Sun Yun-pai method to evaluate the mixing effect. The test results are shown in Table 4.

[0089] The co-toxicity coefficient (CTC value) of the mixture was calculated according to the following formula:

[0090]

[0091] Where: ATI - Measured toxicity index of the mixture; S - LC50 of the standard agent; M - LC50 of the mixture.

[0092] TTI = TIA × PA + TIB × PB

[0093] Where: TTI - Theoretical toxicity index of the mixture; TIA - Toxicity index of agent A; PA - Percentage content of agent A in the mixture; TIB - Toxicity index of agent B; PB - Percentage content of agent B in the mixture.

[0094]

[0095] Where: CTC - Co-toxicity coefficient; ATI - Measured toxicity index of the mixture; TTI - Theoretical toxicity index of the mixture.

[0096] When the co-toxicity coefficient (CTC) of the mixture ≥ 120, it shows a synergistic effect; when CTC ≤ 80, it shows an antagonistic effect; when 80 < CTC < 120, it shows an additive effect.

[0097] Table 4 Results of joint toxicity determination of the composition containing Compound I-72 against Bemisia tabaci

[0098]

[0099] It can be seen from the table (Table 4) that the mixture of Compound I-72 and pyraclostrobin shows a synergistic effect against adult Bemisia tabaci at ratios of 40:1 to 1:20.

[0100] Example 5

[0101] Control effect of the composition containing Compound I-72 against sheath blight of rice.

[0102] Test target: Sensitivity strain of Rhizoctonia solani cultured indoors for sheath blight of rice.

[0103] The experiment adopted the seedling potting method. The experimental crop was rice. The experimental method was to cultivate the seedlings in the experimental material greenhouse until the two-leaf stage. Then, foliar spray treatment was carried out on a crop sprayer according to the designed dose. After 24 hours of the chemical treatment, the test target fungus was inoculated. The inoculated experimental materials were all cultivated in an artificial climate chamber. When the blank control was fully diseased, the results were investigated. The disease grading and the calculation method of control efficacy were both referred to the Agricultural Industry Standard of the People's Republic of China [Guidelines for Indoor Bioassay Tests of Fungicide Pesticides]. The results are shown in Table 5.

[0104] The test conditions, the preparation of the liquid medicine, and the evaluation method were the same as those in Example 1.

[0105] Table 5 Control effect of the composition containing Compound I-72 on sheath blight of rice

[0106]

[0107] It can be seen from the table (Table 5) that the mixture of Compound I-72 with pyraclostrobin and syringomycin showed a synergistic effect on sheath blight of rice at the ratio of 1:40 to 1:1.

[0108] The description of the above embodiments is only used to help understand the method of the present invention and its core idea. It should be pointed out that for those of ordinary skill in the art of this technology, without departing from the principle of the present invention, several improvements and modifications can still be made to the present invention, and these improvements and modifications also fall within the protection scope of the claims of the present invention. From the above technical solutions, it can be seen that the insecticidal and bactericidal composition of the present invention has the advantages of improving the drug efficacy, expanding the insecticidal spectrum, reducing the amount of pesticides used, lowering the agricultural cost, reducing the residue of pesticides on crops, reducing the environmental pollution, being safe for humans and animals, having good environmental compatibility, and the action target is not easy to develop drug resistance. The composition of the present invention can be applied to the control of various pests and diseases of a variety of crops and can be widely applied in the agricultural field.

Claims

1. An insecticidal and bactericidal composition, characterized in that: The composition is an active component of component A and component B, wherein the active component A is a piperic acid derivative compound with the following structure, and the active component B is selected from enestroburin, azoxystrobin, pyraoxystrobin, pyraclostrobin or caryomycin; The piperic acid derivative compound has the following structure: ； The weight ratio of the active components is 50:1 to 1:

50.

2. The composition according to claim 1, wherein: The weight ratio of the active components is 40:1 - 1:

20.

3. Use of the composition according to claim 1 for controlling Agrotis ypsilon, white grubs, Bemisia tabaci, and sheath blight of rice.

4. A method for controlling pests and / or diseases, characterized in that, The composition of claim 1 is applied at an effective dose to the growth medium of Agrotis ypsilon, white grubs, Bemisia tabaci, and sheath blight of rice.

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