An intelligent specimen storage system based on the Internet of Things
Through an intelligent storage system based on the Internet of Things, the inaccurate dose control, insufficient environmental monitoring and safety problems in the specimen storage system are solved, and the precise monitoring and safe storage of specimens are achieved, which improves the operating efficiency and safety of the laboratory.
Patent Information
- Application Number
- CN202410631294.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-21
- Publication Date
- 2024-12-10
- Estimated Expiration
- 2044-05-21
AI Technical Summary
The existing specimen storage systems lack precise dose control, insufficient environmental monitoring, low operating efficiency and insufficient safety, and cannot intelligently identify specimen dose and labels, resulting in inaccuracy and safety risks of experimental results.
Design an intelligent storage system based on the Internet of Things, including server, storage module, induction measurement module, marking acquisition module, marking evaluation module and specimen steering module, and realizes identity identification code identification, dose analysis, temperature and humidity control and automated management. Accurate dose monitoring and safe storage.
It improves the intelligence of the storage and management of specimens, ensures dose accuracy and safety, reduces labor intensity, improves the level of automation management, and reduces the work burden of the laboratory.
Smart Images

Figure CN118419395B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of medical equipment, and in particular to an intelligent specimen storage system based on the Internet of Things. Background Art
[0002] In the fields of biology, chemistry, medicine and other scientific research, specimen management and processing is the basis and key part of experimental work. Specimens may include but are not limited to chemical reagents, biological samples, drugs and other scientific materials.
[0003] For example, the intelligent specimen storage rack disclosed in Chinese patent CN117141927A solves the problems of intelligent counting, easy tracking, and stable storage, but still cannot intelligently sense the dose of the specimen and cannot determine whether the dose in the specimen meets the minimum requirement of the experiment.
[0004] At the same time, the prior art still has the following problems:
[0005] Imprecise dose control: Many existing specimen storage systems lack precise dose control mechanisms, which may lead to inaccurate use of specimens in experiments, affecting the reproducibility and reliability of experimental results.
[0006] Inadequate monitoring of environmental conditions: The stability of specimens often depends on specific storage conditions, such as temperature, humidity, and light. Traditional systems often do not provide continuous environmental monitoring or automatic adjustment functions, which may cause damage to sensitive specimens or degradation of performance.
[0007] Operational inefficiencies: Manual specimen processing and management is time-consuming and prone to errors, especially in laboratory environments that require processing large numbers or multiple types of specimens.
[0008] Safety Issues: When working with hazardous or infectious specimens, improper storage and handling may pose risks to laboratory personnel and the environment.
[0009] The present invention is made to solve the common problems in the art such as the inability to monitor dosage, the inability to intelligently identify labels, the lack of storage security, the lack of dosage management and the low intelligence level. Summary of the invention
[0010] The purpose of the present invention is to propose an intelligent specimen storage system based on the Internet of Things in response to the current deficiencies.
[0011] In order to overcome the shortcomings of the prior art, the present invention adopts the following technical solutions:
[0012] A specimen intelligent storage system based on the Internet of Things, the specimen intelligent storage system comprising a server and a test tube specimen with an identity identification code attached thereto, the specimen intelligent storage system further comprising a storage module, an induction metering module, a mark collection module, a mark evaluation module and a specimen steering module, the server being connected to the storage module, the induction metering module, the mark collection module, the mark evaluation module and the specimen steering module respectively;
[0013] The storage module stores the identified test tube specimens, the induction metering module measures the stored test tube specimens, the mark collection module collects the identity identification code of the test tube specimens, the mark evaluation module compares the identity identification code with the patient identity corresponding to the test tube specimen 9 to form a comparison result, and the specimen diversion module triggers the diversion of the test tube specimen according to the comparison result;
[0014] The induction metering module includes a sensing unit, a dose analysis unit and a data storage device. The sensing unit is arranged in the storage module and senses the weight of the test tube specimen. The dose analysis unit analyzes the dose in the test tube specimen according to the weight data collected by the sensing unit to obtain dose data. The data storage device stores the weight data collected by the sensing unit and the dose data analyzed by the dose analysis unit.
[0015] The dosage analysis unit matches and binds the dosage data with the identity authentication code corresponding to the test tube specimen.
[0016] Optionally, the storage module includes a storage unit and a temperature and humidity control unit, the storage unit is used to store the test tube specimens, and the temperature and humidity control unit controls the environment in which the test tube specimens are stored in the storage unit to maintain the temperature and humidity of the storage environment;
[0017] The storage unit includes a storage seat, a storage component and a locking component. The storage seat is provided with a rotating cavity. The storage seat is used to place the storage component and the locking component, wherein the storage component is used to support and place the test tube specimen to maintain the test tube in an upright state, and the locking component is used to lock the storage component so that the storage component can be removably locked in the storage seat and the bottom of the test tube specimen is against the sensing unit.
[0018] Optionally, the sensing unit includes a placement seat, a placement groove arranged on the upper end surface of the placement seat, and a weight sensor arranged in the placement groove, wherein the placement groove is arranged on the upper end surface of the placement seat and is arranged relative to the bottom of the test tube specimen so that the test tube specimen can be against the top of the weight sensor;
[0019] Wherein, the placement grooves are arranged at equal intervals along the axis of the storage seat.
[0020] Optionally, the dose analysis unit obtains the weight data of the test tube specimen collected by the sensing unit, and calculates the equivalent dose V of the test tube specimen according to the following formula:
[0021]
[0022] Wherein, M is the mass of the specimen in the test tube specimen, D(T) is the typical density value after temperature adjustment, and f(T, RH) is the temperature and humidity correction factor.
[0023] Optionally, the tag collection module includes a collection unit and a support unit, the support unit supports the collection unit, and the collection unit collects the identity identification code of the test tube specimen;
[0024] The collection unit comprises a collector and a fixing seat, the fixing seat is used to place the collector, and the collector collects the identity identification code on the test tube specimen.
[0025] Optionally, the temperature and humidity control unit includes a temperature sensor, a humidity sensor, a humidifier, a dehumidifier and a heater, the temperature sensor is used to collect the temperature in the storage cavity, the humidity sensor collects humidity data in the storage cavity, the humidifier humidifies the humidity in the storage cavity, the dehumidifier removes moisture in the storage cavity, and the heater heats the temperature in the storage cavity so that the temperature in the storage cavity is constant within a set storage temperature range.
[0026] Optionally, the specimen steering module includes a rotating chamber, a steering seat, a steering drive mechanism, an identification probe, and at least one steering marking member, the steering seat is nested in the outer periphery of the placement seat, the steering drive mechanism is arranged on the inner wall of the rotating chamber, and is drivingly connected to the steering seat to form a steering portion, so that the steering seat rotates along its own axis, the steering portion is arranged in the rotating chamber, at least one steering marking member is arranged on the steering seat, and is evenly spaced along the outer side wall of the steering seat, the identification probe is arranged on the inner wall of the rotating chamber, and extends toward one side of at least one steering marking member to identify at least one steering marking member.
[0027] Optionally, the identity authentication code includes a barcode, a QR code, an RFID tag, an NFC tag and a magnetic stripe.
[0028] Optionally, the marking evaluation module includes a comparison unit and an activation unit, wherein the comparison unit compares the identity identification code with the patient identity corresponding to the test tube specimen 9, and the activation unit activates the sensing unit and the dose analysis unit according to the comparison result, so that the sensing unit and the dose analysis unit can perform weight collection and dose analysis on the test tube specimen;
[0029] When the comparison unit successfully compares and verifies, the activation unit is triggered to activate the sensing unit and the dose analysis unit, and the dose of the test tube specimen is bound to the patient's identity.
[0030] Optionally, the storage component includes a storage rack and at least one accommodating cavity arranged on the storage rack, and the at least one accommodating cavity is arranged on the storage rack at equal intervals and distributed at equal intervals along the axis of the storage rack;
[0031] Wherein, the circumference of at least one accommodating cavity is matched with the circumference of the test tube specimen, so that the test tube specimen can be placed in the accommodating cavity.
[0032] The beneficial effects achieved by the present invention are:
[0033] 1. Through the cooperation between the label evaluation module, the label collection module and the specimen steering module, the test tube specimens can be stored and identified with labels, ensuring that the entire system has the advantages of high intelligence, strong test tube specimen operation and maintenance management capabilities, reduced labor intensity and high dose sensing accuracy;
[0034] 2. Through the cooperation between the storage unit and the temperature and humidity control unit, the storage of the test tube specimens is made more scientific and intelligent, ensuring that the entire system has the advantages of high intelligence, high storage convenience and good temperature and humidity management effect;
[0035] 3. Through the cooperation between the storage module and the sensing module, the dosage of the test tube specimen can be accurately monitored, ensuring that the entire system has the advantages of high dosage monitoring accuracy, high intelligence and reliable dosage management;
[0036] 4. Through the cooperation between the magnetic attraction component and the locking component, the test tube specimen can be easily stored in the storage cavity, improving the flexibility and convenience of loading and unloading the test tube specimen;
[0037] 5. Through the cooperation of the storage module, the sensing module, the mark collection module, and the mark evaluation module, the automation management level of the entire device is improved, and the test tube storage and sampling are integrated into one, which reduces the labor intensity of the laboratory. BRIEF DESCRIPTION OF THE DRAWINGS
[0038] The present invention can be further understood from the following description in conjunction with the accompanying drawings. The components in the figures are not necessarily drawn to scale, but the emphasis is placed on illustrating the principles of the embodiments. In different views, the same reference numerals designate the same parts.
[0039] Figure 1 It is an overall block diagram of the present invention.
[0040] Figure 2 It is a block diagram of the storage unit and the temperature and humidity control unit of the present invention.
[0041] Figure 3 It is a block diagram of the inductive metering module, the marking evaluation module and the marking acquisition module of the present invention.
[0042] Figure 4 It is a schematic diagram of the evaluation process of the posture evaluation unit of the present invention.
[0043] Figure 5 It is a front view schematic diagram of the present invention.
[0044] Figure 6 for Figure 5 Schematic cross-sectional view at AA in the middle.
[0045] Figure 7 It is a side view schematic diagram of the storage module of the present invention.
[0046] Figure 8 It is a top view schematic diagram of the storage module of the present invention.
[0047] Fig. 9 for Figure 8 Schematic cross-sectional view at the middle BB.
[0048] Fig.10 for Fig. 9 Enlarged schematic diagram of point C in the middle.
[0049] Fig.11 for Fig. 9 Enlarged schematic diagram of point D in the middle.
[0050] Explanation of the accompanying drawings: 1. storage box; 2. box cover; 3. handle; 4. vibrator; 5. hinge; 6. switch; 7. temperature sensor; 8. humidity sensor; 9. test tube specimen; 10. storage chamber; 11. humidifier; 12. accelerometer; 13. dehumidifier; 14. heater; 15. support rod; 16. collection unit; 17. placement seat; 18. storage seat; 19. adsorption seat; 20. control switch; 21. storage rack; 22. accommodating chamber; 23. identity authentication code; 24. weight sensor; 25. steering seat; 26. rotating gear; 27. connecting rod; 28. steering drive mechanism; 29. rotating chamber; 30. magnetic adsorption member; 31. evaporator; 32. delivery pipeline; 33. liquid nitrogen pump; 34. nitrogen storage tank; 35. electronic exhaust valve. DETAILED DESCRIPTION
[0051] The following is an explanation of the embodiments of the present invention through specific embodiments. Those skilled in the art can understand the advantages and effects of the present invention from the contents disclosed in this specification. The present invention can be implemented or applied through other different specific embodiments, and the details in this specification can also be modified and changed in various ways based on different viewpoints and applications without departing from the spirit of the present invention. In addition, the drawings of the present invention are only simple schematic illustrations and are not depicted according to actual sizes. It is stated in advance. The following embodiments will further explain the relevant technical contents of the present invention in detail, but the disclosed contents are not intended to limit the scope of protection of the present invention.
[0052] Embodiment 1: According to Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 , Figure 7 , Figure 8 , Fig. 9 , Fig.10 and Fig.11 As shown, this embodiment provides an intelligent specimen storage system based on the Internet of Things, the intelligent specimen storage system includes a server, and a test tube specimen with an identity authentication code 23 attached thereto, the intelligent specimen storage system also includes a storage module, an induction metering module, a mark collection module, a mark evaluation module and a specimen steering module, the server is respectively connected to the storage module, the induction metering module, the mark collection module, the mark evaluation module and the specimen steering module, and the intermediate data and process data of the storage module, the induction metering module, the mark collection module, the mark evaluation module and the specimen steering module are stored in the database of the server for query or call;
[0053] The storage module stores the identified test tube specimens, the induction metering module measures the stored test tube specimens, the mark collection module collects the identity identification code 23 of the test tube specimens, the mark evaluation module compares the identity identification code 23 with the patient identity corresponding to the test tube specimen 9 to form a comparison result, and the specimen diversion module triggers the diversion of the test tube specimen according to the comparison result;
[0054] The intelligent specimen storage system further comprises a central processing unit, which is respectively connected to the storage module, the sensing metering module, the safety monitoring module, the marking collection module, the marking evaluation module and the specimen steering module, and centrally controls the storage module, the sensing metering module, the safety monitoring module, the marking collection module, the marking evaluation module and the specimen steering module based on the central processing unit, and stores the control data in the server, so as to improve the processing accuracy and reliability of the entire system for specimen storage;
[0055] In this embodiment, the test tube specimen is placed in the storage module, and the identification code attached to the outside of the test tube specimen 9 is collected and evaluated by the mark collection module and the mark evaluation module to obtain the identity of the test tube. At the same time, during the collection process, the test tube specimen 9 is rotated by the steering module so that the identification code 23 on the test tube specimen 9 can be collected. After the test tube specimen 9 is collected, the dose of the test tube specimen 9 is sensed by the sensing module, and the identified identification code 23 is matched and bound with the dose.
[0056] Optionally, the identity authentication code 23 includes but is not limited to the following: barcode, QR code, RFID tag, NFC tag and magnetic stripe, which needs to be selected according to the actual usage scenario;
[0057] The sensing metering module includes a sensing unit, a dose analysis unit and a data storage device. The sensing unit is arranged in the storage module and senses the weight of the test tube specimen. The dose analysis unit analyzes the dose of the specimen in the test tube specimen according to the weight data collected by the sensing unit to obtain dose data. The data storage device stores the weight data collected by the sensing unit and the dose data analyzed by the dose analysis unit. The analysis can obtain the specimen volume as the dose data by subtracting the weight of the test tube specimen from the weight of the test tube specimen and dividing the result by the density of the specimen.
[0058] Wherein, the dosage analysis unit matches and binds the dosage data with the identity authentication code 23 corresponding to the test tube specimen;
[0059] Optionally, the storage module includes a storage unit and a temperature and humidity control unit, the storage unit is used to store the test tube specimens, and the temperature and humidity control unit controls the environment in which the test tube specimens are stored in the storage unit to maintain the temperature and humidity of the storage environment;
[0060] The storage unit comprises a storage seat 18, a storage member and a locking member. The storage seat 18 is provided with a rotating cavity 29. The storage seat 18 is used to place the storage member and the locking member. The storage member is used to support and place the test tube specimen to maintain the test tube in an upright state. The locking member is used to lock the storage member so that the storage member can be detachably locked in the storage seat 18 and the bottom of the test tube specimen is against the sensing unit.
[0061] The storage module further comprises a storage box 1, wherein the storage box 1 comprises a storage cavity 10, and the storage cavity 10 is used for placing the induction metering module, the mark collection module, the mark evaluation module and the specimen steering module;
[0062] The storage box 1 includes a box cover 2, a hinge 5 and a switch 6. The box cover 2 is arranged above the storage cavity 10 and connected to one side edge of the storage cavity 10 through the hinge 5. The switch 6 is arranged on the other side of the box cover 2 to realize locking or unlocking the box cover 2.
[0063] The storage component includes a storage rack 21 and at least one accommodating cavity 22 arranged on the storage rack 21, wherein the at least one accommodating cavity 22 is arranged on the storage rack 21 at equal intervals and is distributed at equal intervals along the axis of the storage rack 21;
[0064] The circumference of at least one accommodating cavity 22 is adapted to the circumference of the test tube specimen 9, so that the test tube specimen 9 can be placed in the accommodating cavity 22;
[0065] Meanwhile, in this embodiment, the storage rack 21 can be detachably connected to the storage seat 18 (ie, adsorbed on the storage seat 18) by the locking member;
[0066] The storage rack 21 is in a cross shape in side view, that is, it includes a rack portion for placing the test tube specimens 9 and a limiting portion connected to the magnetic attraction member, and the rack portion and the limiting portion are connected to each other to form a cross shape;
[0067] In this embodiment, the locking member is arranged on the limiting portion;
[0068] The locking member includes a magnetic adsorption member 30, an adsorption seat 19, and a control switch 20, wherein the control switch 20 is used to control the adsorption of the magnetic adsorption member 30 and the adsorption seat 19, wherein the adsorption force between the magnetic adsorption member 30 and the adsorption seat 19 can be achieved by controlling the current on the magnetic adsorption member 30;
[0069] The magnetic adsorption member 30 is disposed on one side end surface of the storage rack 21 facing the storage seat 18, and the adsorption seat 19 is disposed on the upper end surface of the storage seat 18 and is disposed opposite to the magnetic adsorption member 30;
[0070] In addition, the control switch 20 is disposed on the upper end surface of the storage rack 21 so that the manager can conveniently operate it to release the adsorption of the storage rack 21 and the storage seat 18;
[0071] In this embodiment, the magnetic attraction member and the locking member cooperate with each other, so that the test tube specimen 9 can be easily stored in the accommodating cavity 22, thereby improving the flexibility and convenience of loading and unloading the test tube specimen 9;
[0072] Optionally, the temperature and humidity control unit includes a temperature sensor 7, a humidity sensor 8, a humidifier 11, a dehumidifier 13 and a heater 14, wherein the temperature sensor 7 is used to collect the temperature in the accommodating cavity 22, the humidity sensor collects humidity data in the accommodating cavity 22, the humidifier 11 humidifies the humidity in the accommodating cavity 22, the dehumidifier 13 removes moisture in the accommodating cavity 22, and the heater 14 heats the temperature in the accommodating cavity 22, so that the temperature in the accommodating cavity 22 is constant within a set storage temperature range;
[0073] In this embodiment, a closed-loop control loop is formed between the temperature sensor 7, the heater 14 and the central processor. When the temperature sensor 7 detects that the temperature in the accommodating cavity 22 is lower than the set storage temperature standard, the temperature sensor 7 feeds back the real-time temperature to the central processor, so that the central processor controls the heater 14 to heat the heater 14, thereby restoring the temperature in the accommodating cavity 22 to the storage temperature standard.
[0074] The storage temperature standard is set by the system according to the actual situation of the stored test tube specimen 9, which is a technical means well known to those skilled in the art. Those skilled in the art can refer to relevant technical manuals to learn about the technology, so it will not be described in detail in this embodiment;
[0075] Similarly, a closed-loop control loop is formed between the humidity sensor 8, the humidifier 11, the dehumidifier 13 and the central processor. The humidity sensor 8 collects the humidity in the accommodating chamber 22. When the humidity in the accommodating chamber 22 is lower than the set storage humidity standard, the humidity data is fed back to the central processor, so that the central processor controls the humidifier 11 to humidify the humidity in the accommodating chamber 22.
[0076] When the humidity in the accommodating chamber 22 is greater than the set storage humidity standard, the humidity data is fed back to the central processor, so that the central processor controls the dehumidifier 13 to dehumidify the humidity in the accommodating chamber 22;
[0077] At the same time, the storage humidity standard is set by the system according to the actual situation of the stored test tube specimen 9, which is a technical means well known to those skilled in the art, and those skilled in the art can refer to the relevant technical manuals to learn the technology, so it will not be described in detail in this embodiment;
[0078] Through the cooperation between the storage unit and the temperature and humidity control unit, the storage of the stored test tube specimens 9 is made more scientific and intelligent, ensuring that the entire system has the advantages of high intelligence, high storage convenience and good temperature and humidity management effect;
[0079] The temperature and humidity control unit further includes a cooling component, which lowers the temperature in the storage chamber 10 to maintain the test tube specimen 9 in a low temperature environment for storage;
[0080] The cooling component includes a liquid nitrogen storage tank 34, a liquid nitrogen pump 33, a delivery pipeline 32, an evaporator 31, a pressure sensor, and an electronic exhaust valve 35. The liquid nitrogen storage tank 34 is used to store liquid nitrogen. One end of the delivery pipeline 32 is connected to the liquid nitrogen storage tank 34, and the other end of the delivery pipeline 32 is connected to the evaporator 31. The liquid nitrogen pump 33 is arranged in the passage of the delivery pipeline 32, and the liquid nitrogen pump 33 is used to extract liquid nitrogen from the storage tank and transmit it to the evaporator 31 through the delivery pipeline 32. The pressure sensor is used to detect the pressure data in the storage chamber 10, and the electronic exhaust valve 35 is used to discharge the nitrogen generated by the evaporation of the liquid nitrogen to prevent the oxygen concentration in the storage chamber 10 from being too low (such as Figure 6 As shown, Figure 6 The color gradient in the middle is a schematic diagram of nitrogen discharge);
[0081] The electronic exhaust valve 35 is set to be electronically controlled, and the electronic exhaust valve 35 is controlled on and off based on the central processor;
[0082] At the same time, the pressure sensor is arranged in the storage cavity 10, and collects the real-time pressure data in the storage cavity 10;
[0083] The temperature in the storage chamber 10 is lowered by the cooling component, so that the storage temperature of the test tube specimen 9 is accurately controlled, the accurate storage of the test tube specimen 9 is improved, and the test tube specimen 9 is prevented from deteriorating to the greatest extent.
[0084] The amount of liquid nitrogen evaporated by the evaporator 31 needs to be regulated according to the actual cooling temperature required to be controlled. This is a technical means well known to those skilled in the art, and therefore will not be described in detail in this embodiment.
[0085] Optionally, the sensing unit includes a placement seat 17, a placement groove arranged on the upper end surface of the placement seat 17, and a weight sensor 24 arranged in the placement groove, wherein the placement groove is arranged on the upper end surface of the placement seat 17 and is arranged relative to the bottom of the test tube specimen 9 so that the test tube specimen 9 can be against the top of the weight sensor 24;
[0086] Wherein, the placement slots are arranged at equal intervals along the axis of the storage seat 18;
[0087] like Fig. 9 As shown, the test tube specimen 9 can just rest against the weight sensor 24 during placement, so that the weight sensor 24 supports the test tube specimen 9;
[0088] Optionally, the dose analysis unit obtains the weight data of the test tube specimen 9 collected by the sensing unit, and calculates the equivalent dose V of the test tube specimen 9 according to the following formula:
[0089]
[0090] Wherein, M is the mass of the specimen in the test tube specimen, that is, the specimen weight, D(T) is the typical density value after temperature adjustment, and f(T, RH) is the temperature and humidity correction factor;
[0091] The typical density value D(T) after temperature adjustment is calculated according to the following formula:
[0092] D(T)=D·(1+α·(TT ref ));
[0093] Where D is the typical density of the sample. In this embodiment, the sample stored in the test tube is human body fluid (such as blood and urine) as an example, T is the current temperature, and T refis the reference temperature, α is the thermal expansion coefficient of the sample material, and its value is determined experimentally. Specifically, for common biological fluids such as blood and urine, their thermal expansion coefficients may have been reported in previous scientific research literature;
[0094] In this embodiment, a step of determining the thermal expansion coefficient α of the sample material is provided:
[0095] S1. Use a dilution instrument or a thermomechanical analyzer (TMA) to measure the volume change of a substance at different temperatures.
[0096] S2. Measure the volume of the sample at the reference temperature and other temperature points;
[0097] S3. Calculate the thermal expansion coefficient α of the sample material:
[0098]
[0099] Where ΔL is the volume change, L ref is the reference volume, ΔT is the temperature change range; the volume change is the volume change after the temperature changes by ΔT.
[0100] In this embodiment, the typical density D of the sample is determined according to the following formula:
[0101] S11. Collect samples: Collect blood and urine samples from multiple individuals with different health conditions to ensure sample representativeness, including individuals of different ages, genders, and health conditions;
[0102] S12. Control measurement conditions
[0103] Temperature control: All measurements should be performed at standardized room temperature, or at a specifically specified temperature (usually 20°C or 37°C, depending on standard laboratory conditions);
[0104] S13, Density Measurement
[0105] Using a density meter: Use a pycnometer or electronic density meter to measure the density of each sample; for each sample, repeat the measurement at least three times to ensure the reliability of the data;
[0106] S14. Record data: record the density readings of all samples;
[0107] Calculate the mean density:
[0108] For each sample, calculate the average of its density readings:
[0109]
[0110] Where D iis the density value of a single measurement, and n is the number of measurements;
[0111] S15. Statistical analysis
[0112] Calculate the overall mean density: Use the average density value of all samples to calculate the overall mean density D of blood and urine total_avg :
[0113]
[0114] Where D avg,j is the average density of each sample, and m is the total number of samples;
[0115] S16. The overall average density of blood and urine D total_avg Determined as the typical density value D for urine and blood samples;
[0116] The temperature and humidity correction factors f(T, RH) are calculated according to the following formula:
[0117] f(T,RH)=1+β 1 ·(TT ref )+β 2 ·(RH-RH ref );
[0118] In the formula, β 1 and β 2 is the temperature coefficient and humidity coefficient obtained by fitting historical data. T is the current temperature, whose value is collected by the temperature sensor. RH is the current humidity, whose value is collected by the humidity sensor. ref and RH ref is the reference temperature and reference humidity (usually laboratory standard conditions);
[0119] The temperature coefficient β obtained by fitting historical data 1 and humidity coefficient β 2 The calculation is performed according to the following steps:
[0120] S21. Data Collection
[0121] Experimental design: Select multiple different temperature (T) and relative humidity (RH) conditions;
[0122] Under each condition, a relevant property of the substance is measured (in this embodiment, the relevant property is specifically density);
[0123] Data Records:
[0124] Ensure multiple measurements under each condition to increase data reliability and reduce the impact of random errors;
[0125] S22. Data preprocessing
[0126] Centralized processing:
[0127] The temperature and humidity data are centered by subtracting the mean value from each value, or by subtracting the reference value (T ref RH ref );
[0128] S23. Linear regression analysis
[0129] Use the linear regression method to fit the data:
[0130] y=1+β 1 ·(TT ref )+β 2 ·(RH-RH ref );
[0131] Where y is the quantity measured in the experiment or study (i.e., the density of the test tube specimen);
[0132] The final temperature coefficient β is obtained by linear regression analysis 1 and humidity coefficient β 2 ;
[0133] In short, the technicians in this field need to perform fitting according to the actual experimental results to determine the temperature coefficient β1 and the humidity coefficient β2. This is a technical means well known to the technicians in this field. The technicians in this field can refer to the relevant technical manuals to learn about the technology, so it will not be described one by one in this embodiment;
[0134] Through the cooperation between the storage module and the sensing module, the dosage of the test tube specimen 9 can be accurately monitored, ensuring that the entire system has the advantages of high dosage monitoring accuracy, high intelligence and reliable dosage management;
[0135] Optionally, the marking collection module includes a collection unit 16 and a support unit, the support unit supports the collection unit 16, and the collection unit 16 identifies the identity code 23 of the test tube specimen 9;
[0136] The collecting unit 16 includes a collector and a fixing seat, the fixing seat is used to place the collector, and the collector collects the identity identification code 23 on the test tube specimen 9;
[0137] In this embodiment, different collectors are used for different identity authentication codes 23;
[0138] For example: if the identity authentication code 23 is a barcode, the collector uses a scanning probe;
[0139] If the identity authentication code 23 is an RFID tag, the collector uses an RFID sensing probe;
[0140] The support unit includes a support rod 15, a support driving mechanism and a telescopic detection member. One end of the support rod 15 is connected to the support driving mechanism to form a support portion, and the other end of the support rod 15 is connected to the fixed seat to adjust the position of the collector, thereby improving the recognition height of the collector. The support rod 15 is configured to be telescopic and realizes a telescopic action under the drive of the support driving mechanism. The telescopic detection member collects the telescopic amount of the support rod 15.
[0141] When the extension amount of the support rod 15 does not match the set extension height, the extension height is fed back to the central processor, and the support drive mechanism is controlled by the central processor so that the support drive mechanism drives the support rod 15, so that the support rod 15 can perform the extension action;
[0142] Optionally, the specimen steering module includes a rotating cavity 29, a steering seat 25, a steering drive mechanism 28, an identification probe, and at least one steering mark, wherein the steering seat 25 is nested in the outer periphery of the placement seat 17, the steering drive mechanism 28 is arranged on the inner wall of the rotating cavity 29, and is drivingly connected to the steering seat 25 to form a steering portion, so that the steering seat 25 rotates along its own axis, the steering portion is arranged in the rotating cavity 29, at least one steering mark is arranged on the outer side wall of the steering seat, and is evenly spaced along the outer side wall of the steering seat, the identification probe is arranged on the inner wall of the rotating cavity 29, and extends toward one side of at least one steering mark to identify at least one steering mark;
[0143] In this embodiment, the specimen steering module further includes a rotating gear 26, which is embedded in the outer periphery of the steering seat 25 and meshes with the steering drive mechanism 28;
[0144] The specimen steering module further includes a connecting rod 27, one end of which is hinged to the bottom wall of the steering seat 25, and the other end of which is connected to the bottom wall of the rotating chamber 29, and the connecting rod 27 is coaxially arranged with the steering seat 25, so that when the steering drive mechanism 28 drives the steering seat 25, it rotates along its own axis;
[0145] In this embodiment, a closed loop is formed between the identification probe, the steering marker and the central processing unit. When the steering marker acquired by the identification probe is inconsistent with the angle required for the current position, the central processing unit is triggered to control the steering drive mechanism 28 to drive the steering seat 25, so that the steering seat 25 rotates. During the rotation, the identification probe recognizes the steering marker in real time, thereby obtaining the real-time angular position, until the rotation angle is consistent with the required angle.
[0146] In this embodiment, at least one turning mark corresponds to a specific angle, so that the identification probe can identify the turning angle of the turning seat 25;
[0147] The marking evaluation module includes a comparison unit and an activation unit. The comparison unit compares the identity authentication code 23 with the identity of the patient corresponding to the test tube specimen 9. The activation unit activates the sensing unit and the dose analysis unit according to the comparison result, so that the sensing unit and the dose analysis unit can collect the weight and analyze the dose of the test tube specimen 9. The dose is a volume (ml), that is, a volume obtained by dividing the weight of a liquid sample by its density.
[0148] In this embodiment, when the test tube specimen 9 collects the patient's body fluid, the identity authentication code 23 on the test tube has been bound to the patient's identity and stored in the database of the server;
[0149] Wherein, when the comparison unit successfully compares and verifies, the activation unit is triggered to activate the sensing unit and the dose analysis unit;
[0150] The comparison unit includes a verifier and a trigger. The verifier obtains the identity authentication code 23 acquired by the mark acquisition module and compares the identity authentication code 23 with the identity of the patient corresponding to the test tube specimen 9. The trigger is used to trigger the mark steering module to perform a rotation action.
[0151] The trigger sends a turning signal to the marking turning module at a fixed interval, so that the marking turning module performs a turning action; at the same time, during the turning process, the identity identification code on the test tube specimen 9 is collected by the marking collection module;
[0152] In this embodiment, the comparison process is: comparing the identity authentication code 23 collected locally with the patient identity corresponding to the test tube specimen 9 in the database;
[0153] If the comparison matches, it means that the identity of the test tube sample 9 has been successfully verified;
[0154] If the comparison does not match, it means that the test tube specimen 9 is missing or missing, and the medical staff is reminded to re-collect the body fluid sample of the corresponding patient;
[0155] In this embodiment, after the identity of the comparison unit is verified, the activation unit is triggered to activate the sensing unit and the dose analysis unit, and the dose of the test tube specimen obtained by analysis is bound to the patient's identity;
[0156] The activation unit includes an activator and a feedback device, wherein the feedback device is used to receive the comparison result of the marking evaluation module, and after the activator receives the feedback signal of the feedback device, the activator is triggered to activate the sensing unit and the dose analysis unit, so that the sensing unit and the dose analysis unit can perform weight collection and dose analysis on the test tube specimen 9;
[0157] In this embodiment, after the dose analysis is completed, the dose of the test tube specimen 9 is bound to the identity identification code 23 of the test tube specimen 9, so that the inspector can dynamically grasp the dose of the test tube specimen;
[0158] Through the cooperation between the label evaluation module, the label collection module and the specimen steering module, the test tube specimen 9 can take into account both storage and label recognition, ensuring that the entire system has the advantages of high intelligence, strong operation and maintenance management capabilities of the test tube specimen 9, reduced labor intensity and high dose sensing accuracy;
[0159] Through the cooperation between the storage module and the sensing module, the mark collection module and the mark evaluation module, the automation management level of the entire device is improved, test tube storage and sampling are integrated into one, and the labor intensity of the laboratory is reduced.
[0160] Embodiment 2: This embodiment should be understood to include all the features of any of the above embodiments, and further improve upon them. Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 , Figure 7 , Figure 8 , Fig. 9 , Fig.10 and Fig.11 As shown, the intelligent specimen storage system further includes a safety monitoring module, and the safety monitoring module manages and protects the test tube specimens;
[0161] The safety monitoring module includes a posture sampling unit, a posture evaluation unit and an interaction unit. The posture sampling unit collects the posture of the accommodating cavity 22. The posture evaluation unit evaluates the test tube specimen 9 according to the stored posture data to form an evaluation result. The interaction unit triggers an interaction prompt to the carrier with the evaluation result of the posture evaluation unit.
[0162] Wherein, the posture sampling unit is arranged on the storage component;
[0163] The posture sampling unit includes an accelerometer 12 and a data recorder, wherein the accelerometer is used to collect the acceleration of the storage component in three spatial axes, and the data recorder stores the acceleration data of the storage component in three spatial axes;
[0164] In this embodiment, if Figure 6 As shown, a three-axis spatial coordinate system XYZ is established with the symmetry center of the storage component, and the acceleration component of the accelerometer on the X axis is a x , the acceleration component of the accelerometer on the Y axis is a y , the acceleration component of the accelerometer on the Z axis is a z ;
[0165] The posture evaluation unit obtains the acceleration data of the three spatial axes measured by the accelerometer, and calculates the tilt index Angle according to the following formula:
[0166]
[0167] In the formula, a x is the acceleration component of the accelerometer on the X-axis, a y is the acceleration component of the accelerometer on the Y axis, a z is the acceleration component of the accelerometer on the Z axis;
[0168] If the tilt index Angle exceeds the deviation threshold safety allowed by the system setting, the interaction unit is triggered to prompt the administrator;
[0169] If the tilt index Angle is lower than the allowed deviation threshold safety set by the system, it means that the tilt angle of the test tube specimen 9 stored in the storage component is within a safe range, and there is no need to prompt the manager;
[0170] The system setting allows the deviation threshold safety to be set by the system or the administrator according to the actual situation. This is a technical means well known to those skilled in the art. Those skilled in the art can refer to relevant technical manuals to learn about the technology, so it will not be described in detail in this embodiment.
[0171] Optionally, the interaction unit includes a vibrator 4 and a receiver, the receiver is used to receive the evaluation result of the posture evaluation unit, and the vibrator 4 triggers a vibration prompt according to the evaluation result to prompt the carrier to give a prompt;
[0172] In this embodiment, the interaction unit may be disposed on the handle 3 of the storage box 1 or at a position that can be directly observed or released by the carrier or administrator;
[0173] Through the mutual cooperation between the safety monitoring module and the storage module, the stored test tube specimens 9 can be made safer, and the test tube specimens 9 can be prevented from spilling due to excessive tilting during storage or transportation, thereby ensuring that the entire system has the advantages of strong protection capability, good protection effect, high intelligence, and good specimen storage management effect.
[0174] The contents disclosed above are only preferred feasible embodiments of the present invention, and do not limit the protection scope of the present invention. Therefore, all equivalent technical changes made using the contents of the present invention specification and drawings are included in the protection scope of the present invention. In addition, the elements therein can be updated as technology develops.
Claims
1. An intelligent specimen storage system based on the Internet of Things, the intelligent specimen storage system comprising a server and a test tube specimen with an identity identification code attached thereto, It is characterized in that The intelligent specimen storage system further comprises a storage module, an induction metering module, a mark collection module, a mark evaluation module and a specimen steering module, and the server is respectively connected to the storage module, the induction metering module, the mark collection module, the mark evaluation module and the specimen steering module; The storage module stores the test tube specimens, the induction metering module measures the stored test tube specimens, the mark collection module collects the identity identification code of the test tube specimens, the mark evaluation module compares the identity identification code with the patient identity corresponding to the test tube specimen to form a comparison result, and the specimen diversion module triggers the diversion of the test tube specimen according to the comparison result; The sensing metering module includes a sensing unit, a dose analysis unit and a data storage device. The sensing unit is arranged in the storage module and senses the weight of the test tube specimen. The dose analysis unit analyzes the dose in the test tube specimen according to the weight data collected by the sensing unit to obtain dose data. The data storage device stores the weight data collected by the sensing unit and the dose data analyzed by the dose analysis unit. The dosage analysis unit matches and binds the dosage data with the identity authentication code corresponding to the test tube specimen.
2. The intelligent specimen storage system based on the Internet of Things according to claim 1, It is characterized in that The storage module includes a storage unit and a temperature and humidity control unit. The storage unit is used to store the test tube specimens. The temperature and humidity control unit controls the environment in which the test tube specimens are stored in the storage unit to maintain the temperature and humidity of the storage environment. The storage unit includes a storage seat, a storage component and a locking component. The storage seat is provided with a rotating cavity. The storage seat is used to place the storage component and the locking component, wherein the storage component is used to support and place the test tube specimen to maintain the test tube in an upright state, and the locking component is used to lock the storage component so that the storage component can be removably locked in the storage seat and the bottom of the test tube specimen is against the sensing unit.
3. The intelligent specimen storage system based on the Internet of Things according to claim 2, It is characterized in that The sensing unit includes a placement seat, a placement groove arranged on the upper end surface of the placement seat, and a weight sensor arranged in the placement groove, wherein the placement groove is arranged on the upper end surface of the placement seat and is arranged relative to the bottom of the test tube specimen so that the test tube specimen can be against the top of the weight sensor; Wherein, the placement grooves are arranged at equal intervals along the axis of the storage seat.
4. The intelligent specimen storage system based on the Internet of Things according to claim 3, It is characterized in that The dose analysis unit obtains the weight data of the test tube specimen collected by the sensing unit, and calculates the equivalent dose V of the test tube specimen according to the following formula: Wherein, M is the mass of the specimen in the test tube specimen, D(T) is the typical density value after temperature adjustment, and f(T, RH) is the temperature and humidity correction factor.
5. The intelligent specimen storage system based on the Internet of Things according to claim 4, It is characterized in that The tag collection module includes a collection unit and a support unit, wherein the support unit supports the collection unit, and the collection unit collects the identity identification code of the test tube specimen; The collection unit comprises a collector and a fixing seat, the fixing seat is used to place the collector, and the collector collects the identity identification code on the test tube specimen.
6. The intelligent specimen storage system based on the Internet of Things according to claim 5, It is characterized in that The temperature and humidity control unit includes a temperature sensor, a humidity sensor, a humidifier, a dehumidifier and a heater. The temperature sensor is used to collect the temperature in the storage cavity, the humidity sensor collects the humidity data in the storage cavity, the humidifier humidifies the humidity in the storage cavity, the dehumidifier removes the moisture in the storage cavity, and the heater heats the temperature in the storage cavity so that the temperature in the storage cavity is constant within a set storage temperature range.
7. The intelligent specimen storage system based on the Internet of Things according to claim 6, It is characterized in that The specimen steering module includes a rotating chamber, a steering seat, a steering drive mechanism, an identification probe, and at least one steering marker. The steering seat is nested in the outer periphery of the placement seat. The steering drive mechanism is arranged on the inner wall of the rotating chamber and is drivingly connected to the steering seat to form a steering portion, so that the steering seat rotates along its own axis. The steering portion is arranged in the rotating chamber. At least one steering marker is arranged on the steering seat and is evenly spaced along the side wall of the steering seat. The identification probe is arranged on the rotating chamber and extends toward one side of at least one steering marker to identify at least one steering marker.
8. The intelligent specimen storage system based on the Internet of Things according to claim 7, It is characterized in that The identity authentication code includes a barcode, a QR code, an RFID tag, an NFC tag and a magnetic stripe.
9. The intelligent specimen storage system based on the Internet of Things according to claim 8, It is characterized in that The marking evaluation module includes a comparison unit and an activation unit, wherein the comparison unit compares the identity authentication code with the patient identity corresponding to the test tube specimen in the database, and the activation unit activates the sensing unit and the dose analysis unit according to the comparison result, so that the sensing unit and the dose analysis unit can perform weight collection and dose analysis on the test tube specimen; When the comparison unit successfully compares and verifies, the activation unit is triggered to activate the sensing unit and the dose analysis unit, and the dose of the test tube specimen is bound to the patient's identity.
10. The intelligent specimen storage system based on the Internet of Things according to claim 9, It is characterized in that The storage component includes a storage rack and at least one accommodating cavity arranged on the storage rack, wherein the at least one accommodating cavity is arranged on the storage rack at equal intervals and is distributed at equal intervals along the axis of the storage rack; Wherein, the circumference of at least one accommodating cavity is matched with the circumference of the test tube specimen, so that the test tube specimen can be placed in the accommodating cavity.
