A steam ablation system

Abstract

The present invention discloses a steam ablation system. In addition to controlling the temperature index of steam output, the steam outlet pressure is also controlled. Through simulation, it can be known that in steam ablation, in addition to temperature, the outlet pressure also has an important influence on the ablation effect. In order to reduce the volume of the steam ablation equipment, the power supply voltages of different modules in the steam ablation equipment are integrated through a multi-channel power supply based on a flyback circuit, and the power supply output voltage is comprehensively regulated by a main control board based on an STM32F29BIT6 chip. At the same time, the main control board also controls the steam generator, ADC parameter conversion, and upper and lower communications of the host computer and other system controls. A temperature measurement module is added to the steam ablation equipment to perform real-time ablation temperature detection. The outlet pressure and outlet temperature can be set arbitrarily, and by matching different steam outlet needles, it can be applied to steam ablation fields in various occasions, such as chronic obstructive pulmonary disease, prostate, and tumor fields that may be involved in the future.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a steam ablation system. Background Art

[0002] Steam thermal ablation is a new technology that achieves therapeutic effects by applying high-temperature water vapor to the target area of ​​the patient. Compared with other ablation technologies, steam ablation has the advantages of low cost, few side effects, and can be used with drugs.

[0003] The current steam ablation equipment has the disadvantages of poor visualization, large size, and large deviation of output steam pressure. The steam ablation equipment on the market is mainly based on foreign steam ablation equipment as a platform for innovation and development, and there are some visualization modules that are not suitable for Chinese people; because the steam ablation system contains a variety of equipment with different power supply voltage levels, each module in the traditional steam ablation equipment must be equipped with a power supply, and the volume of the power supply increases, so the traditional steam ablation equipment is bulky; traditional steam ablation equipment only uses temperature as the output indicator of the equipment, but in fact, it can be known through simulation that the output steam pressure will also have an important impact on the ablation effect. Summary of the invention

[0004] The technical problem to be solved by the present invention is to provide a steam ablation system with good ablation effect, small size, and the ability to perform real-time ablation temperature detection, which is widely used.

[0005] In order to solve the above technical problems, the present invention provides a steam ablation system, including: a main control board, a steam generating module, a water pump module, a temperature measuring module, an ADC sampling and conversion module and a host computer; the water pump module is connected to the steam generating module, and the amount of liquid delivered to the steam generating module per minute by the water pump module is controlled by the main control board. The steam generating module sets the vaporization temperature, outlet temperature and outlet air pressure value of its internal steam generator through the main control board, so as to ensure that the steam outlet temperature and outlet air pressure of the steam ablation system are adjustable as a whole. The host computer sends control parameters to the main control board, and the main control board controls the flow rate of water delivered to the steam generator module by the water pump module and the vaporization temperature of the steam generator. degree and outlet temperature; at the same time, the water pump module collects the current flow rate and the steam generation module collects the current vaporization temperature, current outlet temperature and current outlet pressure of the steam generator through the ADC sampling and conversion module and feeds them back to the control board, wherein the ADC sampling and conversion module converts the physical signal inside the steam generator into a digital signal and feeds it back to the main control board, which is then transmitted to the host computer by the main control board for real-time monitoring of the vaporization temperature, outlet temperature and outlet pressure inside the steam generator; the temperature measurement module collects the temperature of the tissue in the thermal ablation area and feeds it back to the main control board, which then transmits the parameters to the host computer, and when the pressure and temperature of the water vapor reach the set value, steam output begins.

[0006] Preferably, in the main control board, the power supply circuit of each module selects a multi-channel output circuit based on a flyback circuit, and the power supply modules are the main control board, the water pump module and the steam generation module. The power supply voltage levels of each module are different. If different power supply modules are used, it will inevitably lead to an increase in volume. The multi-channel output power supply circuit controlled by the main control board only occupies a small part of the main control board's memory, which greatly reduces the volume of the power supply module.

[0007] Preferably, a flyback circuit topology model of a multi-channel output circuit is adopted by using voltage weighted feedback control, and the power supply voltage of the main control board, the power supply voltage of the steam generation module and the power supply voltage of the water pump module are sampled to the main control board respectively, and returned to the switch tube of the primary side of the flyback circuit for PWM control after weighted adjustment by the main control board; the weighted adjustment performs control with different degrees of accuracy by setting the weight coefficient of each module, and the power supply voltage weight coefficient of the steam generation module is set to be greater than that of the water pump module, and the power supply voltage weight coefficient of the main control board is the smallest. Because the power supply voltage fluctuation of the steam generator cannot be too large, and the water pump is second, at the same time, the power supply voltage range of the main control board can be supplied within a wide range.

[0008] Preferably, the steam generator in the steam generating module sets the vaporization temperature and the outlet temperature through the main control board, and then controls it through the steam generator control circuit, so as to ensure the adjustable steam outlet temperature of steam ablation; and the current vaporization temperature, outlet temperature and internal air pressure of the steam generator are fed back in real time, transmitted to the host computer through the main control board for real-time monitoring, and when the air pressure reaches the ideal predetermined value, the steam generator is turned on for ablation.

[0009] Preferably, after the ablation time is set and the device is turned on, when the outlet air pressure is lower than 95% of the set value during operation, the steam generator closes the outlet, and the host computer stops timing. After the air pressure stabilizes to the set pressure value, the steam generator reopens the outlet, and the host computer continues timing; when the outlet air pressure is higher than 105% of the set value, the steam generator closes the outlet, the host computer stops timing, and opens the air release switch next to it, and passes steam into a small water tank next to it containing a certain solution. After the air pressure stabilizes to the set pressure value, the steam generator closes the air release switch, reopens the outlet, and the host computer continues timing.

[0010] Preferably, the temperature measurement module includes a temperature measuring needle, a temperature measuring circuit and an AD conversion circuit which are connected in sequence, and the output end of the AD conversion circuit is connected to the main control board.

[0011] Preferably, the temperature measurement circuit includes a voltage divider circuit and a low-pass filter circuit, the input end of the voltage divider circuit is connected to the temperature measuring needle, and the output end of the voltage divider circuit is electrically connected to the input end of the low-pass filter circuit.

[0012] Preferably, the temperature sampling circuit in the ADC sampling and conversion module mainly realizes the analog-to-digital conversion of the vaporization temperature and the outlet temperature of the steam generating device, and the air pressure sampling circuit mainly realizes the analog-to-digital conversion of the vaporization temperature and the outlet air pressure of the steam generating device.

[0013] Preferably, the host computer includes a human-computer interaction interface, which displays the current vaporization temperature, outlet temperature and air pressure value of the steam generator in real time.

[0014] The beneficial effects of the present invention are as follows: (1) In addition to controlling the temperature index of steam output, the present invention also controls the steam outlet pressure. Through simulation, it can be seen that in steam ablation, in addition to temperature, the outlet pressure also has an important influence on the ablation effect; (2) In order to reduce the volume of the steam ablation device, the present invention integrates the power supply voltages of different modules in the steam ablation device through a multi-channel power supply based on a flyback circuit, and the main control board based on the STM32F29BIT6 chip performs comprehensive regulation of the power output voltage. At the same time, the main control board also controls the steam generator, ADC parameter conversion, and upper and lower communication with the host computer and other system controls; (3) The present invention adds a temperature measurement module to the steam ablation device, which can be used with a temperature measuring needle to perform real-time ablation temperature detection; (4) The present invention can arbitrarily set the outlet pressure and outlet temperature. By matching different steam outlet needles, it can be applied to steam ablation fields in various occasions, such as chronic obstructive pulmonary disease, prostate, and tumor fields that may be involved in the future. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 This is a block diagram of the steam ablation system of the present invention.

[0016] Figure 2 A system block diagram for setting the outlet temperature of the steam generator gasification temperature domain of the present invention.

[0017] Figure 3 It is a schematic diagram of the air pressure control flow of the steam ablation system outlet of the present invention.

[0018] Figure 4 This is a structural block diagram of the temperature measurement module of the present invention.

[0019] Figure 5 The present invention is a schematic diagram of the power supply circuit of each part controlled by the main control board based on the flyback circuit.

[0020] FIG. 6( a ) is a diagram showing the simulation results of steam ablation at 1 atmosphere pressure of the present invention.

[0021] FIG. 6( b ) is a diagram showing the simulation results of steam ablation at 5 atmospheres of pressure according to the present invention. DETAILED DESCRIPTION

[0022] like Figure 1As shown, a steam ablation system includes: a control and power integrated system (main control board) based on STM32, a steam generating module, a water pump module, a temperature measurement module, an ADC sampling and conversion module and a host computer; the water pump module connects the water pump motor with the hanging bottle and the steam generator, and controls the amount of liquid delivered to the steam generator by the water pump module per minute through the main control board; the steam generating module can set the vaporization temperature and outlet temperature of its internal steam generator (the set vaporization temperature is lower than the outlet temperature) and the outlet air pressure value through the main control board, so as to ensure that the steam outlet temperature and outlet air pressure of the steam ablation system are adjustable as a whole; the host computer sends control parameters to the main control board, and the main control board controls the flow rate of the water pump module to deliver water to the steam generator and the vaporization temperature and outlet temperature of the steam generator, and at the same time feeds back the current flow rate of the water pump, the current vaporization temperature of the steam generator, the current outlet temperature and the current outlet air pressure value to the control board; the temperature measurement module The temperature of the tissue in the thermal ablation area is collected and fed back to the main control board, and then the main control board transmits the parameters to the host computer; when the outlet air pressure is lower than 95% of the set value, the steam generator closes the outlet and the host computer stops timing. After the air pressure stabilizes to the set air pressure value, the steam generator reopens the outlet and the host computer continues timing; when the outlet air pressure is higher than 105% of the set value, the steam generator closes the outlet, the host computer stops timing, and opens the air release switch next to it to pass steam into a small water tank next to it containing a certain solution. After the air pressure stabilizes to the set air pressure value, the steam generator closes the air release switch, reopens the outlet, and the host computer continues timing; the present invention has many internal devices and different power supply voltage levels. In order to ensure the reduction of volume, this experiment designs a multi-channel power supply system based on a flyback circuit controlled by the main control board. Therefore, the main control board not only realizes the control of the steam ablation equipment, but also takes into account the power supply system control of different components inside the steam ablation equipment.

[0023] like Figure 2 As shown, the steam generation module can set the size of the vaporization temperature and the size of the outlet temperature through the main control board and the steam generator control circuit, thereby ensuring that the steam ablation outlet temperature is adjustable. The vaporization chamber mainly heats the water into a steam state, and the steam heating chamber mainly heats the steam further to the temperature required for ablation; thereby ensuring that the steam ablation outlet temperature is adjustable. And the current vaporization temperature and outlet temperature are fed back in real time and transmitted to the host computer through the main control board for real-time monitoring.

[0024] like Figure 3As shown, when the outlet air pressure of the steam generating device is lower than 95% of the set value, the steam generator closes the outlet, the host computer stops timing, and after the air pressure stabilizes to the set pressure value, the steam generator reopens the outlet, and the host computer continues timing; when the outlet air pressure is higher than 105% of the set value, the steam generator closes the outlet, the host computer stops timing, and opens the air release switch next to it, and steam is passed into a small water tank next to it containing a certain solution. After the air pressure stabilizes to the set pressure value, the steam generator closes the air release switch, reopens the outlet, and the host computer continues timing.

[0025] like Figure 4 As shown, the temperature measurement module includes a temperature measuring needle, a temperature measuring circuit and an AD conversion circuit connected in sequence, and the output end of the AD conversion circuit is connected to the main control board. Further, the temperature measurement circuit includes a voltage divider circuit and a low-pass filter circuit, the input end of the voltage divider circuit is connected to the temperature measuring needle, and the output end of the voltage divider circuit is electrically connected to the input end of the low-pass filter circuit.

[0026] like Figure 5 As shown, the control and power integrated system (main control board) based on STM32 is mainly composed of a control circuit and a power circuit. Integrating them together can improve space utilization and reduce costs; a multi-channel output circuit based on a flyback circuit is selected, and the main power supply modules are the main control board, the water pump and the steam generator. Further, because the power supply voltage levels of the designed steam ablation equipment are different, and the power supply voltage accuracy of the steam generator is high, followed by the water pump and the main control board, a voltage-weighted feedback control multi-channel output flyback circuit topology model is adopted. The main control board power supply voltage, the steam generator power supply voltage and the water pump power supply voltage are sampled separately to the main control board, and returned to the switch tube of the primary side of the flyback circuit for PWM control after weighted adjustment by the main control board. Because the power supply voltage fluctuation of the steam generator cannot be too large, followed by the water pump, at the same time, the power supply voltage range of the main control board can be powered within a large range, so the power supply voltage weight coefficient of the steam generator is set to be greater than the water pump, and the power supply voltage weight coefficient of the main control board is the smallest.

[0027] As shown in FIG6( a ), the liver ablation result calculated by COMSOL software at a standard atmospheric pressure and a steam temperature of 130° C. for 5 minutes was found to have a long diameter of 30 mm and a short diameter of 28 mm.

[0028] As shown in FIG6( b ), the liver ablation results of steam ablation for 5 minutes at five standard atmospheres and a steam temperature of 130° C. were calculated by COMSOL software, and it can be seen that the long diameter is 32 mm and the short diameter is 30 mm.

Claims

1. A steam ablation system, characterized in that: include: Main control board, steam generation module, water pump module, temperature measurement module, ADC sampling and conversion module and host computer; the water pump module is connected to the steam generation module, and the main control board is used to control the amount of liquid delivered to the steam generation module per minute by the water pump module. The steam generation module sets the vaporization temperature, outlet temperature and outlet pressure value of its internal steam generator through the main control board, so as to achieve adjustable steam outlet temperature and outlet pressure of the steam ablation system. The host computer sends control parameters to the main control board, and the main control board controls the flow rate of water delivered to the steam generator module by the water pump module and the vaporization temperature and outlet temperature of the steam generator. At the same time, the water pump module will The current flow rate and steam generation module collect the current vaporization temperature, current outlet temperature and current outlet pressure of the steam generator through the ADC sampling and conversion module and then feed it back to the control board, where the ADC sampling and conversion module converts the physical signal inside the steam generator into a digital signal and feeds it back to the main control board, which is then transmitted to the host computer for real-time monitoring of the vaporization temperature, outlet temperature and outlet pressure inside the steam generator; the temperature measurement module collects the temperature of the tissue in the thermal ablation area and feeds it back to the main control board, which then transmits the parameters to the host computer. When the pressure and temperature of the water vapor reach the setting, steam output begins; In the main control board, the power supply circuit of each module selects a multi-channel output circuit based on the flyback circuit, and the power supply module provides power for the main control board, the water pump module and the steam generation module; the flyback circuit topology model of the multi-channel output circuit is controlled by voltage weighted feedback, and the power supply voltage of the main control board, the power supply voltage of the steam generation module and the power supply voltage of the water pump module are sampled to the main control board respectively, and returned to the switch tube on the primary side of the flyback circuit for PWM control after weighted adjustment by the main control board; the weighted adjustment performs control with different degrees of accuracy by setting the weight coefficient of each module, and the power supply voltage weight coefficient of the steam generation module is set to be greater than that of the water pump module, and the power supply voltage weight coefficient of the main control board is the smallest.

2. The steam ablation system according to claim 1, characterized in that: The steam generator in the steam generation module sets the vaporization temperature and outlet temperature through the main control board, and then controls it through the steam generator control circuit to ensure the adjustable steam outlet temperature of steam ablation; and the current vaporization temperature, outlet temperature and internal air pressure of the steam generator are fed back in real time and transmitted to the host computer through the main control board for real-time monitoring. When the air pressure reaches the ideal preset value, the steam generator is turned on for ablation.

3. The steam ablation system according to claim 2, characterized in that: After setting the ablation time and turning on the equipment, when the outlet air pressure is lower than 95% of the set value during operation, the steam generator closes the outlet and the host computer stops timing. After the air pressure stabilizes to the set pressure value, the steam generator reopens the outlet and the host computer continues timing. When the outlet air pressure is higher than 105% of the set value, the steam generator closes the outlet, the host computer stops timing, and opens the air release switch next to it to pass steam into a small water tank next to it containing a certain solution. After the air pressure stabilizes to the set pressure value, the steam generator closes the air release switch, reopens the outlet, and the host computer continues timing.

4. The steam ablation system according to claim 1, characterized in that: The temperature measurement module comprises a temperature measuring needle, a temperature measuring circuit and an AD conversion circuit which are connected in sequence, and the output end of the AD conversion circuit is connected to the main control board.

5. The steam ablation system according to claim 4, characterized in that: The temperature measurement circuit includes a voltage divider circuit and a low-pass filter circuit. The input end of the voltage divider circuit is connected to the temperature measurement needle, and the output end of the voltage divider circuit is electrically connected to the input end of the low-pass filter circuit.

6. The steam ablation system according to claim 1, characterized in that: A voltage-weighted feedback control multi-output flyback circuit topology model is adopted. The main control board power supply voltage, steam generator power supply voltage and water pump power supply voltage are sampled to the main control board respectively. After weighted adjustment by the main control board, they are returned to the switch tube on the primary side of the flyback circuit for PWM control. The power supply voltage weight coefficient of the steam generator is set greater than that of the water pump, and the power supply voltage weight coefficient of the main control board is the smallest.

7. The steam ablation system according to claim 1, characterized in that: The host computer includes a human-computer interaction interface, which displays the current vaporization temperature, outlet temperature and air pressure value of the steam generator in real time.

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