Composition with soothing, whitening and firming effects and application thereof

Abstract

The present invention relates to a composition having soothing, whitening and firming effects and its application, wherein the composition comprises ascorbic acid, Mirabilis jalapa extract, carnosine, Kapok extract, ubiquinone, β-glucan, panthenol, bisabolol and ginger root extract. The composition provided by the present invention cooperates with each other and synergizes to effectively moisturize, repair skin barrier, comprehensively slow down the oxidation of cells, reduce the generation of free radicals, brighten the skin tone, reduce melanin synthesis, promote the metabolism of skin cells, prevent skin aging and sagging, and reduce wrinkles, and has excellent soothing, whitening and firming effects.

Description

Technical Field

[0001] The present invention relates to the technical field of cosmetics, and in particular to a composition with soothing, whitening and firming effects and application thereof. Background Art

[0002] With the development of modern society, people's work and life pace is getting faster and faster, mental stress is getting greater and greater, and many external factors such as bad living habits, harsh environment, ultraviolet rays, etc. have a negative impact on our skin. More and more people are facing problems such as dry skin, rough skin, inelasticity, dull skin tone, and large pores. With the improvement of the quality of life, people are paying more and more attention to the scientific nature of skin care.

[0003] Vitamin C, also known as ascorbic acid, is an antioxidant that can inhibit the activity of tyrosinase, inhibit the production of melanin, and play a whitening role; it can also eliminate free radicals in the skin, protect collagen, and play an antioxidant and anti-aging role.

[0004] CN109939055A discloses a sustained antioxidant beauty composition, comprising the following components: water, butylene glycol, β-glucan, ascorbic acid, betaine, trehalose, yeast fermentation product filtrate, niacinamide, salvia miltiorrhiza extract, panthenol, hexylene glycol, caprylhydroxamic acid, phloretin, sodium hyaluronate, glutathione, sodium γ-polyglutamate, mannitol, squalane, hydrogenated lecithin, bisabolol, ginger root extract, tocopherol, and ferulic acid.

[0005] CN109223660A discloses a rejuvenating and anti-aging peptide cream and a preparation method thereof, wherein the ingredients are as follows: water, 1,3-butylene glycol, methylparaben, panthenol, niacinamide, sodium hyaluronate, disodium ethylenediaminetetraacetic acid; cetearyl glucoside, HE olive oil emulsifier, cetearyl alcohol, caprylyl glycol, propylene glycol, 1,3-propylene glycol, triethoxycaprylylsilane, isohexadecane, caprylic / capric triglyceride, isononyl isononanoate, ascorbic acid, VE acetate, polydimethylsiloxane; ethylhexylglycerin; carnosine, filtrate of callus culture of Eryngium maritima, small molecule polypeptide nutrient essence, aluminum starch octenylsuccinate, mica powder, mirabilis extract, caprylhydroxamic acid, phenoxyethanol, hydrolyzed collagen, glycyrrhiza glabra, ubiquinone, lecithin; caramel pigment, and flavor.

[0006] In the prior art, the content of ascorbic acid in cosmetics is low and it is easily inactivated and cannot play a better role. Therefore, providing a composition with a high ascorbic acid content and having soothing, whitening and firming effects has good application prospects. Summary of the invention

[0007] In order to solve the above technical problems, the present invention provides a composition having soothing, whitening and firming effects and its application. The multiple active ingredients in the composition provided by the present invention cooperate with each other and synergize to achieve excellent technical effects in soothing, whitening and firming.

[0008] To achieve this object, the present invention adopts the following technical solutions:

[0009] In a first aspect, the present invention provides a composition having soothing, whitening and firming effects, the composition comprising: ascorbic acid, Mirabilis jalapa extract, carnosine, kapok extract, ubiquinone, β-glucan, panthenol, bisabolol and ginger root extract.

[0010] The various active ingredients in the composition provided by the present invention cooperate with each other and synergize to enhance their effectiveness, can effectively moisturize, repair the skin barrier, comprehensively slow down the oxidation of cells, reduce the generation of free radicals, brighten the skin tone, reduce melanin synthesis, promote the metabolism of skin cells, prevent skin aging and sagging, and reduce wrinkles, and has excellent soothing, whitening and firming effects.

[0011] In the present invention, ascorbic acid is an antioxidant that can provide protection against photodamage, neutralize oxidative stress, act as a free radical scavenger, and prevent oxidative damage induced by ultraviolet rays and ozone; at the same time, it can brighten the skin tone, reduce melanin synthesis, improve acne-prone skin, and reduce the appearance of acne; in addition, it also has anti-aging activity, can promote collagen synthesis, contribute to the formation of skin barrier, promote fibroblast proliferation, and increase the ceramide content in keratin cells.

[0012] In the present invention, the Mirabilis jalapa extract can comprehensively slow down the oxidation of cells, reduce the generation of free radicals, restore the original luster of the skin, and make the skin color more even; at the same time, it re-stimulates the internal metabolic mechanism, improves the activity of skin cells as a whole, and strengthens the generation of energy; in addition, it also helps the skin repair the damage caused to the skin during the day, promotes the elimination of toxins, and strengthens the skin's microcirculation system.

[0013] In the present invention, carnosine can inhibit the glycation reaction, prevent the cross-linking and solidification of macromolecules in the dermis that cause wrinkle formation and elasticity loss, and promote the synthesis of collagen; at the same time, it can effectively inhibit oxidative damage as an antioxidant, remove reactive oxygen free radicals (ROS), and has the ability to chelate metal ions; in addition, it can also protect skin cells from DNA damage caused by ultraviolet radiation, and prevent and protect against damage from infrared rays.

[0014] In the present invention, the kapok flower extract is non-toxic and non-sensitizing, can effectively enhance the antioxidant activity, and effectively resist inflammatory aging; at the same time, it can effectively enhance the whitening activity, and the inhibition rate of tyrosinase reaches 34%; in addition, it can also balance the skin microecology, reduce wrinkles, and improve dull skin tone.

[0015] In the present invention, ubiquinone is an energy generating element of biological cells, which brings energy and vitality to the body and skin. It is also one of the most important antioxidants in the body, which can remove active oxygen in the body, promote the metabolism of skin cells, and improve the dry and rough condition of the skin. It exists in every cell and is the power source for producing collagen, hyaluronic acid, cell tissue fluid, etc., making the skin white and plump.

[0016] In the present invention, β-glucan is green and natural, highly effective in moisturizing, soothing and stabilizing, can increase the moisture content of the skin's stratum corneum, improve the skin and alleviate the stinging effect of lactic acid; at the same time, it can repair the skin barrier, has anti-aging and firming effects, and can effectively resist inflammatory aging.

[0017] In the present invention, panthenol has an excellent moisturizing effect, can improve the hydration of the stratum corneum, reduce transepidermal water loss, improve skin roughness and soothe irritated skin; in addition, it can activate fibroblast proliferation, accelerate epithelial cell regeneration, and help wound healing.

[0018] In the present invention, both bisabolol and ginger root extract can significantly alleviate the redness of the skin and can soothe the skin for a long time.

[0019] Preferably, the composition comprises, by mass, 900-1000 parts of ascorbic acid (for example, 920 parts, 930 parts, 940 parts, 950 parts, 960 parts, 970 parts, 980 parts, etc.), 1.5-8.5 parts of Mirabilis jalapa extract (for example, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, etc.), 0.5-20 parts of carnosine (for example, 1 part, 2 parts, 4 parts, 8 parts, 15 parts, 18 parts, etc.), 60-190 parts of kapok extract (for example, 80 parts, 100 parts, 120 parts, 140 parts, 160 parts, 180 parts, etc.), 4-8 parts of ubiquinone (for example, The invention relates to an aqueous solution of at least 40% aqueous solution of at least 20% aqueous solution of at least 20% aqueous solution of at least 25% aqueous solution of at least 30% aqueous solution of at least 45% aqueous solution of at least 20% aqueous solution of at least 30% aqueous solution of at least 25 ...

[0020] When the composition of the present invention satisfies the above mass ratio, the soothing, whitening and firming effects thereof are more significant.

[0021] In a second aspect, the present invention provides a use of the composition having soothing, whitening and firming effects according to the first aspect in the preparation of cosmetics.

[0022] Preferably, the mass fraction of the composition having soothing, whitening and firming effects in the cosmetic is 1-15% (for example, 2%, 4%, 6%, 8%, 10%, 12%, 14%, etc.).

[0023] Preferably, the cosmetics include: facial masks, lotions, toners, facial creams, essences, make-up removers or cleansing products.

[0024] In a third aspect, the present invention provides a facial mask with soothing, whitening and firming effects, the facial mask comprising: a moisturizer, a metal ion blocker, a stabilizer, an emollient, a thickener, a skin conditioner and water; the skin conditioner comprises the composition with soothing, whitening and firming effects according to the first aspect, astaxanthin and ferulic acid.

[0025] Preferably, the facial mask comprises, by mass percentage, 5-15% of a moisturizing agent (for example, 6%, 8%, 10%, 12%, 14%, etc.), 0.01-0.05% of a metal ion blocking agent (for example, 0.015%, 0.02%, 0.025%, 0.03%, 0.035%, 0.04%, 0.045%, etc.), 0.1-1% of a stabilizer (for example, 0.2%, 0.4%, 0.5%), , 0.6%, 0.8%, etc.), emollient 5-15% (for example, 6%, 8%, 10%, 12%, 14%, etc.), thickener 4-10%, (for example, 5%, 6%, 7%, 8%, 9%, etc.) skin conditioner 5-15% (for example, 6%, 8%, 10%, 12%, 14%, etc.) and water 60-85% (for example, 64%, 68%, 72%, 76%, 80%, 84%, etc.).

[0026] Preferably, the moisturizing agent includes any one or a combination of at least two of glycerin, butylene glycol, sodium hyaluronate, 1,2-hexanediol, 1,2-pentanediol, 1,3-propylene glycol, xylitol glucoside, anhydroxylitol, xylitol, allantoin, glucose or betaine.

[0027] Preferably, the metal ion blocking agent comprises disodium EDTA.

[0028] Preferably, the stabilizer comprises any one of sodium chloride or p-hydroxyacetophenone or a combination of both.

[0029] Preferably, the emollient comprises any one of cyclopentasiloxane, polydimethylsiloxane or squalane, or a combination of at least two thereof.

[0030] Preferably, the thickener comprises hydroxypropyl starch phosphate.

[0031] Preferably, the ingredients in the facial mask are in the form of liquid and powder respectively, and the liquid and powder are mixed and stirred during use.

[0032] The powder includes ascorbic acid as a thickener and a skin conditioning agent.

[0033] The liquid preparation comprises a moisturizer, a metal ion blocking agent, a stabilizer, an emollient, water and a skin conditioner including Mirabilis jalapa extract, carnosine, kapok extract, ubiquinone, beta-glucan, panthenol, bisabolol and ginger root extract.

[0034] In the present invention, the facial mask is divided into powder and liquid, wherein ascorbic acid is present in the powder, which solves the problem of its easy inactivation in water and weakened efficacy, and at the same time increases the content of ascorbic acid in the facial mask so that it can fully exert its effect.

[0035] In the present invention, when the facial mask is used, the powder and the liquid are mixed and stirred to obtain a semi-permeable gel-like facial mask, which can be applied freely on the face without restricting facial movements, thereby avoiding waste caused by the flow of facial mask liquid and reducing the risk of overhydration of facial skin caused by cloth-type facial masks. At the same time, efficient replenishment is achieved, and the effects of whitening and removing spots, increasing skin elasticity, and soothing and tightening are effectively exerted.

[0036] In the present invention, there are two phases of water and oil in the liquid. When a specific hydroxypropyl starch phosphate is selected as a thickener in the powder, a gel-like facial mask obtained by mixing the liquid and the powder is non-sticky, easy to spread, and has an excellent feel when used.

[0037] In a fourth aspect, the present invention provides a method for preparing a facial mask having soothing, whitening and firming effects according to the third aspect, the preparation method comprising the preparation of a liquid and the preparation of a powder;

[0038] The preparation method of the liquid preparation comprises the following steps:

[0039] (1) mixing a humectant, a metal ion blocking agent, a stabilizer and water, stirring, heating and maintaining the temperature to obtain an aqueous phase;

[0040] (2) mixing the emollients, stirring, heating and maintaining the temperature to obtain an oil phase;

[0041] (3) stirring the aqueous phase to homogenize and then mixing it with the oil phase, stirring and cooling, and then adding the Mirabilis jalapa extract, carnosine, kapok extract, ubiquinone, β-glucan, panthenol, bisabolol and ginger root extract in the skin conditioner to obtain the liquid;

[0042] Among them, the order of step (1) and step (2) is not specific;

[0043] The preparation method of the powder comprises: grinding ascorbic acid in a skin conditioner and mixing and stirring with a thickener to obtain the powder.

[0044] Preferably, in step (1), the temperature is raised to 70-90°C (for example, 72°C, 75°C, 78°C, 80°C, 82°C, 85°C, 88°C, etc.).

[0045] Preferably, in step (1), the insulation time is 10-20 min (for example, it can be 12 min, 14 min, 15 min, 16 min, 18 min, etc.).

[0046] Preferably, in step (2), the temperature is raised to 70-80°C (for example, 72°C, 74°C, 76°C, 78°C, etc.).

[0047] Preferably, in step (2), the insulation time is 5-10 min (for example, 6 min, 7 min, 7.5 min, 8 min, 9 min, etc.).

[0048] Preferably, in step (3), the homogenization time is 2-5 min (for example, it can be 2.5 min, 3 min, 3.5 min, 4 min, 4.5 min, etc.).

[0049] Preferably, in step (3), the temperature is lowered to 30-50°C (for example, 32°C, 35°C, 38°C, 40°C, 42°C, 45°C, 48°C, etc.).

[0050] Preferably, in the powder preparation method, the stirring time is 30-60 min (for example, it can be 35 min, 40 min, 45 min, 50 min, 55 min, etc.).

[0051] Compared with the prior art, the present invention has at least the following beneficial effects:

[0052] (1) The various active substances in the composition provided by the present invention cooperate with each other and synergistically enhance the effect, which can repair the skin barrier, brighten the skin tone, prevent skin aging and sagging, and reduce wrinkles, and has the effects of moisturizing, soothing, whitening and tightening.

[0053] (2) The present invention provides a facial mask with soothing, whitening and firming effects. In a preferred embodiment, the present invention provides a powder-liquid separation facial mask, wherein the powder contains ascorbic acid. The facial mask provided by the present invention can be mixed and used immediately, thus avoiding the problem of ascorbic acid being inactivated in water. At the same time, the liquid contains both water-soluble and oil-soluble functional ingredients, and a compound combination of multiple soothing ingredients, whitening ingredients and firming ingredients, which has excellent effects of relieving skin irritation, brightening skin tone and increasing skin elasticity.

[0054] (3) The facial mask with soothing, whitening and firming effects provided by the present invention has a unique texture, a crystal clear appearance, is easy to spread, has excellent spreadability, and is refreshing and non-sticky. After washing off, the skin instantly becomes bright, white and tender. DETAILED DESCRIPTION

[0055] For the convenience of understanding the present invention, the present invention lists the following embodiments. It should be understood by those skilled in the art that the embodiments are only to help understand the present invention and should not be regarded as specific limitations of the present invention.

[0056] The sources of raw materials used in the following examples, comparative examples and application examples are as follows:

[0057] Ascorbic acid was purchased from DSM Nutritional Products Ltd.; Mirabilis jalapa extract was purchased from NAOLYS; carnosine was purchased from Dezhixin Flavors & Fragrances (Nantong) Co., Ltd.; kapok extract was purchased from Best Pharmaceuticals (Guangzhou) Co., Ltd.; ubiquinone was purchased from Draco Natural Products Inc.; β-glucan was purchased from Best Pharmaceuticals (Guangzhou) Co., Ltd.; panthenol was purchased from BASF (China) Co., Ltd.; bisabolol / ginger root extract was purchased from Dezhixin Flavors & Fragrances (Nantong) Co., Ltd.; hydroxypropyl starch phosphate was purchased from Nouryon Chemicals (Boxing) Co., Ltd.;

[0058] The weight percentages of the raw materials mentioned above are all calculated based on the actual content of the effective ingredients contained in the commercially available raw materials. The commercially available raw materials may also selectively contain any one or a combination of at least two of solvents, fillers, diluents, stabilizers, pH adjusters, antibacterial agents, antioxidants or impurities within the permitted range.

[0059] Other raw materials are common commercially available products and will not be described in detail here.

[0060] Example 1

[0061] The present embodiment provides a composition having soothing, whitening and firming effects, wherein the composition comprises the following components in parts by mass: 950 parts of ascorbic acid, 5 parts of Mirabilis jalapa extract, 10 parts of carnosine, 120 parts of kapok flower extract, 6 parts of ubiquinone, 0.7 parts of β-glucan, 100 parts of panthenol, 12 parts of bisabolol and 0.07 parts of ginger root extract.

[0062] Example 2

[0063] The present embodiment provides a composition having soothing, whitening and firming effects, wherein the composition comprises the following components in parts by mass: 900 parts of ascorbic acid, 1.5 parts of Mirabilis jalapa extract, 0.5 parts of carnosine, 60 parts of kapok flower extract, 4 parts of ubiquinone, 0.2 parts of β-glucan, 40 parts of panthenol, 7 parts of bisabolol and 0.04 parts of ginger root extract.

[0064] Example 3

[0065] The present embodiment provides a composition having soothing, whitening and firming effects, which comprises the following components in parts by mass: 1000 parts of ascorbic acid, 8.5 parts of Mirabilis jalapa extract, 20 parts of carnosine, 190 parts of kapok flower extract, 8 parts of ubiquinone, 1.2 parts of β-glucan, 170 parts of panthenol, 17 parts of bisabolol and 0.1 parts of ginger root extract.

[0066] Comparative Example 1

[0067] This comparative example provides a composition with soothing, whitening and firming effects, which is different from Example 1 only in that it does not contain ascorbic acid, and its weight parts are distributed according to the proportion of Mirabilis jalapa extract, carnosine, kapok extract and ubiquinone.

[0068] Comparative Example 2

[0069] This comparative example provides a composition with soothing, whitening and firming effects, which is different from Example 1 only in that it does not contain kapok flower extract, and its weight parts are distributed according to the ratio of ascorbic acid, carnosine, Mirabilis jalapa extract and ubiquinone.

[0070] Comparative Example 3

[0071] This comparative example provides a composition with soothing, whitening and firming effects, which is different from Example 1 only in that it does not contain ubiquinone, and its weight parts are distributed according to the proportion of ascorbic acid, carnosine, kapok extract and Mirabilis jalapa extract.

[0072] Comparative Example 4

[0073] This comparative example provides a composition with soothing, whitening and firming effects, which is different from Example 1 only in that it does not contain Mirabilis jalapa extract, and its weight proportions are distributed according to the ratio of ascorbic acid, carnosine, kapok extract and ubiquinone.

[0074] Comparative Example 5

[0075] This comparative example provides a composition with soothing, whitening and firming effects, which is different from Example 1 only in that it does not contain carnosine, and its weight parts are distributed according to the proportions of ascorbic acid, Mirabilis jalapa extract, Kapok extract and ubiquinone.

[0076] Comparative Example 6

[0077] This comparative example provides a composition having soothing, whitening and firming effects, which is different from Example 1 only in that it does not contain panthenol, and its weight proportions are distributed according to the ratio of β-glucan, bisabolol and ginger root extract.

[0078] Comparative Example 7

[0079] This comparative example provides a composition with soothing, whitening and firming effects, which is different from Example 1 only in that it does not contain bisabolol and ginger root extract, and their weight parts are distributed according to the ratio of β-glucan, panthenol and ginger root extract.

[0080] Comparative Example 8

[0081] This comparative example provides a composition with soothing, whitening and firming effects, which is different from Example 1 only in that it does not contain β-glucan, and its weight proportions are distributed according to the ratio of panthenol, bisabolol and ginger root extract.

[0082] Application Example 1

[0083] This application example provides a facial mask with soothing, whitening and firming effects. The formula of the facial mask is as follows:

[0084]

[0085]

[0086] The preparation method of the facial mask includes the preparation of a liquid and a powder, and the preparation method of the liquid includes the following steps:

[0087] (1) Mixing a humectant, a metal ion blocking agent, a stabilizer and water, stirring and heating to 80° C. for 15 minutes to obtain an aqueous phase;

[0088] (2) mixing the emollients, heating to 75° C. with stirring and maintaining the temperature for 7.5 min to obtain an oil phase;

[0089] (3) stirring the aqueous phase for 3 minutes and then mixing it with the oil phase, stirring and cooling to 40° C., adding the Mirabilis jalapa extract, carnosine, kapok extract, ubiquinone, β-glucan, panthenol, bisabolol and ginger root extract in the skin conditioner to obtain the liquid;

[0090] The preparation method of the powder comprises: grinding ascorbic acid in a skin conditioner, adding the grinder to grind twice, and then mixing with a thickener and stirring for 45 minutes to obtain the powder.

[0091] Application Example 2

[0092] This application example provides a facial mask with soothing, whitening and firming effects. The formula of the facial mask is as follows:

[0093]

[0094]

[0095] The preparation method of the facial mask includes the preparation of a liquid and a powder, and the preparation method of the liquid includes the following steps:

[0096] (1) Mixing a humectant, a metal ion blocking agent, a stabilizer and water, stirring and heating to 70° C. for 20 minutes to obtain an aqueous phase;

[0097] (2) mixing the emollients, heating to 70° C. with stirring and maintaining the temperature for 10 min to obtain an oil phase;

[0098] (3) stirring the aqueous phase for 5 minutes and then mixing it with the oil phase, stirring and cooling to 30° C., adding the Mirabilis jalapa extract, carnosine, kapok extract, ubiquinone, β-glucan, panthenol, bisabolol and ginger root extract in the skin conditioner to obtain the liquid;

[0099] The preparation method of the powder comprises: grinding ascorbic acid in a skin conditioner, adding the grinder to grind twice, and then mixing with a thickener and stirring for 60 minutes to obtain the powder.

[0100] Application Example 3

[0101] This application example provides a facial mask with soothing, whitening and firming effects. The formula of the facial mask is as follows:

[0102]

[0103]

[0104] The preparation method of the facial mask includes the preparation of a liquid and a powder, and the preparation method of the liquid includes the following steps:

[0105] (1) Mixing a humectant, a metal ion blocking agent, a stabilizer and water, stirring and heating to 90° C. for 10 minutes to obtain an aqueous phase;

[0106] (2) mixing the emollients, heating to 80° C. with stirring and maintaining the temperature for 5 min to obtain an oil phase;

[0107] (3) stirring the aqueous phase for 2 minutes and then mixing it with the oil phase, stirring and cooling to 50° C., adding the Mirabilis jalapa extract, carnosine, kapok extract, ubiquinone, β-glucan, panthenol, bisabolol and ginger root extract in the skin conditioner to obtain the liquid;

[0108] The preparation method of the powder comprises: grinding ascorbic acid in a skin conditioner, adding the grinder to grind twice, and then mixing with a thickener and stirring for 30 minutes to obtain the powder.

[0109] Comparative Application Examples 1-8

[0110] This comparative application example provides 8 facial masks with soothing, whitening and firming effects. The only difference between it and Application Example 1 is that the skin conditioner in the facial mask is replaced with the composition provided in Comparative Examples 1-8 in equal amounts; the preparation method refers to Application Example 1.

[0111] Application Example 4

[0112] This application example provides a facial mask with soothing, whitening and firming effects. The only difference between this application example and application example 1 is that sodium carboxymethyl starch is used as a thickener. The preparation method refers to application example 1.

[0113] Application Example 5

[0114] This application example provides a facial mask with soothing, whitening and firming effects. The only difference between this application example and application example 1 is that sodium alginate is used as a thickener. The preparation method refers to application example 1.

[0115] Application Example 6

[0116] This application example provides a facial mask with soothing, whitening and firming effects. The only difference between this application example and application example 1 is that ammonium polyacryloyldimethyltaurate is used as a thickener. The preparation method refers to application example 1.

[0117] Test Example 1

[0118] Soothing, whitening, freckle removal, and firming efficacy tests

[0119] (1) Test samples: facial masks with soothing, whitening and firming effects provided in Application Examples 1-3 and Comparative Application Examples 1-8

[0120] (2) Test purpose: To set up a self-controlled before-and-after test, collect skin a* value, skin L* value, skin ITA° value and skin elasticity R2 value through non-invasive testing method, and analyze the skin spot area ratio after taking photos with VISIA-CR to evaluate the soothing, whitening and firming effects of the mask.

[0121] (3) Product use:

[0122] Application area: face

[0123] Usage: Mix the water and powder in the mask at a mass ratio of 5.4:1 for 0.5-1min to obtain a translucent gel-like paste mask. After cleansing your face in the morning and evening, take an appropriate amount of the mask on the palm of your hand and apply it evenly on the entire face. Wash it off with clean water after 15 minutes.

[0124] Use period: 28 days

[0125] (4) Subjects

[0126] Inclusion criteria:

[0127] * Healthy Chinese people;

[0128] *Age 18 to 51 years old;

[0129] *People with red, dull, noticeable spots and sagging facial skin;

[0130] * Subjects who are currently using hormone replacement therapy or hormone birth control should be able to ensure that they maintain their original usage habits during the trial period, and subjects who are not using such hormones should ensure that they do not use such hormones during the trial period;

[0131] * No allergic diseases, no history of allergies to cosmetics and other external preparations;

[0132] *Voluntarily participate in the trial, comply with the trial requirements, and provide timely feedback if any discomfort occurs.

[0133] Exclusion criteria:

[0134] * Use of antihistamines in the past week or immunosuppressants in the past month;

[0135] * Use of any anti-inflammatory drugs in the tested area in the past two months;

[0136] * Patients with insulin-dependent diabetes mellitus;

[0137] *Breastfeeding or pregnant women;

[0138] * Patients who are receiving treatment for respiratory diseases;

[0139] *People with allergic constitution, allergic dermatitis, or a history of skin diseases;

[0140] *People who are receiving dermatological treatment, or those who have taken hydroxy acids, whitening and anti-aging drugs within one month;

[0141] *The test area may have large birthmarks, scratches, white spots, moles, keloids, etc. which may affect the testers.

[0142] Target number of cases: 36 qualified subjects will be selected, ensuring that at least 30 subjects are completed in the end.

[0143] Screening failure, subject dropout and replacement principles:

[0144] *Unenrolled subjects, that is, subjects signed the informed consent form but failed to be enrolled because they did not meet the inclusion / exclusion criteria;

[0145] * Subjects who leave after randomization or group assignment are considered dropouts. Subjects who fail to complete the study for any reason are considered dropouts, and no additional supplements will be made in this case;

[0146] * Dropout principle: The subject actively requests to withdraw; has poor compliance and cannot use the sample product and cooperate with the test as required; has adverse reactions / discomfort during the test and cannot continue the test.

[0147] (5) Test items:

[0148] Test content:

[0149]

[0150]

[0151] Adverse reaction evaluation:

[0152] The subjects use the test products according to the product usage instructions, and observe whether the subjects have skin reactions according to the skin reaction grading standards in the table below at each follow-up visit. If the subjects have any adverse reactions, they should stop using the test products immediately and be examined by professionals to determine whether to terminate the use of the products according to the situation. For any adverse reactions and other related events that occur during the test, the executor shall record and immediately report to the initiator.

[0153] Skin reactions Grading No response 0 Faint erythema 1 Erythema, infiltration, papules 2 Erythema, edema, papules, blisters 3 Erythema, edema, bullae 4

[0154] (6) Test process:

[0155] Test time points: before use, 14 days after use, and 28 days after use;

[0156] Test environment: Temperature: 21.0℃±1.0℃; Relative humidity: 50%±10%;

[0157] Testing process:

[0158] (6.1) Subjects signed informed consent before enrollment, cleaned the test area with facial cleanser before each test, and sat in a constant temperature and humidity environment (temperature 21.0℃±1.0℃; relative humidity: 50%±10%) for at least 20 minutes;

[0159] (6.2) Arrange data collection for the subjects before using the product, 14 days after using the product, and 28 days after using the product, using a skin tester to collect skin parameters and images each time;

[0160] (6.3) After the test, use Excel, SPSS, FrameScan33 and other software to perform statistical analysis to analyze the data changes before and after the subjects use the test product, and draw conclusions on whether the product is effective based on the calculation results.

[0161] (7) Test equipment and parameter description

[0162] Test equipment:

[0163] * Skin-Colorimeter CL400 (Courage & Khazaka, Germany)

[0164] *Facial image photography and analysis system VISIA-CR (Canfield, USA)

[0165] * Skin elasticity tester Cutometer MPA580 (Courage & Khazaka, Germany)

[0166] Test parameter explanation:

[0167] (7.1) Skin color: The lower the a* value, the less red the skin is; the higher the L* value, the brighter the skin is; the higher the ITA° value, the lighter the skin color is. Unit: dimensionless;

[0168] (7.2) Skin spot area ratio: The lower the value, the smaller the spot area ratio. Unit: dimensionless;

[0169] (7.3) Skin elasticity R2 value: The higher the value, the better the skin elasticity. Unit: dimensionless.

[0170] (8) Result determination

[0171]

[0172]

[0173] (9) Data analysis methods

[0174] Descriptive statistics were performed on the measured values ​​of the test area, including quantity, mean, standard deviation, minimum, median, and maximum values. If the test data were normally distributed, the paired t-test was used for statistical analysis; if the test data were non-normally distributed, the Wilcoxon signed-rank test was used for statistical analysis.

[0175] The statistical methods all adopted two-tailed test, and the test level was α=0.05.

[0176] In the formula, D0 is the basic value of skin parameters before the test area uses the product; D14 is the value of skin parameters after the test area uses the product for 14 days; D28 is the value of skin parameters after the test area uses the product for 28 days.

[0177] (10) Test completion status: After screening, a total of 36 qualified subjects were selected, and finally 36 subjects completed the entire test.

[0178] (11) Test results

[0179] The average values ​​of the change rates of the test parameters after using the product for 14 days and 28 days compared with before use are calculated, and the results are shown in Table 1:

[0180] Table 1

[0181]

[0182] The test results show that:

[0183] (1) It can be seen from Application Examples 1 to 3 that the present invention provides a reasonable compounding of multiple active ingredients, and the various ingredients in the resulting composition cooperate with each other to synergistically enhance the effect, thereby having excellent soothing, whitening and firming effects.

[0184] (2) Through the comparison between Application Example 1 and Comparative Application Examples 1-8, it can be seen that in the present invention, β-glucan, panthenol, bisabolol and ginger root extract cooperate with each other to have a synergistic technical effect in soothing the skin; ascorbic acid, Mirabilis jalapa extract, carnosine, kapok flower extract and ubiquinone cooperate with each other to have a synergistic technical effect in tightening the skin; ascorbic acid, Mirabilis jalapa extract, carnosine, kapok flower extract and ubiquinone cooperate with each other to have a synergistic technical effect in whitening the skin.

[0185] Test Example 2

[0186] Mixing time and product appearance test

[0187] Test sample: The facial mask with soothing, whitening and firming effects provided in Application Examples 1, 4-6

[0188] Test method:

[0189] Take equal amounts of the aqueous solution and powder in the facial masks provided in Application Examples 1 and 4-6, and mix them in a mass ratio of 5.4:1. Test the time required for the powder and the liquid to be evenly mixed, and observe the appearance of the facial mask obtained after mixing.

[0190] Test results:

[0191] The test results of the facial masks with soothing, whitening and firming effects provided by Application Examples 1 and 4-6 are shown in Table 2.

[0192] Table 2

[0193]

[0194]

[0195] The test results show that by using a specific hydroxypropyl starch phosphate as a thickener, the powder and liquid in the mask can be quickly and evenly mixed within 1 minute, and the appearance is a non-flowing to semi-flowing colorless, transparent, and delicate gel-like paste, which meets the development requirements of mask products.

[0196] When sodium carboxymethyl starch is used as a thickener in Application Example 4, although the powder prepared can be evenly mixed with the liquid within 1 minute, the paste system structure collapses and the paste does not take shape because it cannot tolerate the strong ionicity of high concentration VC.

[0197] When sodium alginate and ammonium polyacryloyldimethyltaurate are used as thickeners in Application Examples 5-6, respectively, although the powder prepared therefrom can be mixed with the liquid to form a non-flowing to semi-flowing colorless, transparent, and delicate gel-like paste, due to its own characteristics, the time required for uniform mixing of the prepared powder and liquid is relatively long, about 5 minutes, which affects the normal use of consumers and does not meet the product development needs.

[0198] Test Example 3

[0199] Mildness test

[0200] Test sample: the facial mask with soothing, whitening and firming effects provided in Application Examples 1-6.

[0201] Test method: 30 healthy volunteers aged between 20 and 60 years old without allergic diseases were selected as test subjects. Each test subject tried the mask provided in Application Examples 1-6 and Comparative Application Examples 1-9. At the same time, a blank experiment was set up without applying the mask as a negative control group. The liquid and powder in the mask were mixed at a mass ratio of 5.4:1, 0.025g was placed in a patch device, and a hypoallergenic tape was applied to the inside of the subject's arm. After 24 hours, the test substance was removed, and the skin reaction was observed after 0.5 hours, 24 hours, and 48 hours. The results were recorded according to the skin reaction grading standard in the human patch test in Chapter 7 of the 2015 version of the "Technical Specifications for Safety of Cosmetics" as shown below.

[0202]

[0203] Test results: The masks with soothing, whitening and firming effects provided in Example 1-6 were tested. The results are shown in Table 3:

[0204] Table 3

[0205]

[0206]

[0207] It can be seen from the above data that the composition of the present invention and the cosmetics containing the same are mild and non-irritating to the skin.

[0208] The applicant declares that the above is only a specific implementation mode of the present invention, but the protection scope of the present invention is not limited thereto. Those skilled in the art should understand that any changes or substitutions that can be easily thought of by those skilled in the art within the technical scope disclosed by the present invention shall fall within the protection scope and disclosure scope of the present invention.

Claims

1. A facial mask with soothing, whitening and firming effects, characterized in that: The facial mask comprises, by mass percentage, 5-15% moisturizing agent, 0.01-0.05% metal ion blocking agent, 0.1-1% stabilizer, 5-15% emollient, 4-10% thickener, 5-15% skin conditioning agent and 60-85% water; The skin conditioning agent comprises a composition having soothing, whitening and tightening effects, astaxanthin and ferulic acid; the composition comprises ascorbic acid, Mirabilis jalapa extract, carnosine, Kapok extract, ubiquinone, β-glucan, panthenol, bisabolol and ginger root extract; The thickener includes hydroxypropyl starch phosphate; The ingredients in the mask are in the form of liquid and powder respectively, and the liquid and powder are mixed and stirred when used; The powder includes ascorbic acid among the thickeners and skin conditioning agents; The liquid preparation comprises a moisturizer, a metal ion blocking agent, a stabilizer, an emollient, water and a skin conditioner including Mirabilis jalapa extract, carnosine, kapok extract, ubiquinone, beta-glucan, panthenol, bisabolol and ginger root extract.

2. The facial mask according to claim 1, characterized in that The composition comprises, by mass, 900-1000 parts of ascorbic acid, 1.5-8.5 parts of Mirabilis jalapa extract, 0.5-20 parts of carnosine, 60-190 parts of kapok extract, 4-8 parts of ubiquinone, 0.2-1.2 parts of beta-glucan, 40-170 parts of panthenol, 7-17 parts of bisabolol and 0.04-0.1 parts of ginger root extract.

3. The facial mask according to claim 1, characterized in that: The moisturizing agent includes any one of glycerin, butylene glycol, sodium hyaluronate, 1,2-hexanediol, 1,2-pentanediol, 1,3-propylene glycol, xylitol glucoside, anhydroxylitol, xylitol, allantoin, glucose or betaine, or a combination of at least two thereof.

4. The facial mask according to claim 1, characterized in that The metal ion blocking agent includes disodium EDTA.

5. The facial mask according to claim 1, characterized in that: The stabilizer includes any one of sodium chloride or p-hydroxyacetophenone or a combination of the two.

6. The facial mask according to claim 1, characterized in that: The emollient includes any one of cyclopentasiloxane, polydimethylsiloxane or squalane, or a combination of at least two of them.

7. A method for preparing a facial mask having soothing, whitening and firming effects according to any one of claims 1 to 6, characterized in that: The preparation method includes the preparation of liquid preparation and the preparation of powder preparation; The preparation method of the liquid preparation comprises the following steps: (1) Mixing a humectant, a metal ion blocking agent, a stabilizer and water, stirring, heating and maintaining the temperature, to obtain an aqueous phase; (2) mixing the emollients, stirring, heating and maintaining the temperature to obtain an oil phase; (3) stirring the aqueous phase to homogenize and then mixing it with the oil phase, stirring and cooling, and then adding the skin conditioner, Mirabilis jalapa extract, carnosine, kapok extract, ubiquinone, β-glucan, panthenol, bisabolol and ginger root extract to obtain the liquid; Among them, the order of step (1) and step (2) is not specific; The preparation method of the powder comprises: grinding ascorbic acid in a skin conditioner and mixing and stirring with a thickener to obtain the powder.

8. The preparation method according to claim 7, characterized in that: In step (1), the temperature is raised to 70-90°C.

9. The preparation method according to claim 7, characterized in that: In step (1), the insulation time is 10-20 minutes.

10. The preparation method according to claim 7, characterized in that: In step (2), the temperature is raised to 70-80°C.

11. The preparation method according to claim 7, characterized in that: In step (2), the insulation time is 5-10 minutes.

12. The preparation method according to claim 7, characterized in that: In step (3), the homogenization time is 2-5 minutes.

13. The preparation method according to claim 7, characterized in that: In step (3), the temperature is lowered to 30-50°C.

14. The preparation method according to claim 7, characterized in that: In the powder preparation method, the stirring time is 30-60 minutes.

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