Pipette with tip supply

Abstract

The application relates to a pipette with a tip supply device, which comprises a pipette body, a tip supply device and a tip supply device driving mechanism, the tip supply device driving mechanism is arranged beside the pipette body, the tip supply device is fixedly arranged at the lower end of the tip supply device driving mechanism, the tip supply device comprises a tip supply device shell, a tip pushing device and a plurality of tips arranged in sequence, the tip supply device shell is provided with a tip outlet through hole penetrating from top to bottom, and a pipette piston cylinder at the lower part of the pipette body penetrates through the tip outlet through hole, the tip pushing device pushes the tips to the tip outlet through hole, the tip supply device driving mechanism drives the tip supply device to move downwards to make the tips cover the pipette nozzle, and a dismounting pin is arranged at the lower part of the inner side of the tip supply device shell to clamp the tips on the pipette nozzle when the tip supply device moves downwards, so that the tips are separated from the pipette nozzle. The pipette can automatically mount and dismount the tips, reduces the labor intensity of operators, improves the pipetting efficiency, and avoids the pollution of the tips by the outside world.

Description

Technical Field

[0001] This invention relates to the field of pipettes, and more specifically to a pipette with a tip feeding device. Background Technology

[0002] A pipette, also known as a pipette gun, is a common tool used for quantitatively transferring liquid samples. It is widely used in fields such as biology, medicine, chemistry, and materials science. The main components of a pipette include a push button, a volume adjustment button, a volume display window, a tip release button, a release rod (tube), a pipette rod, a tip, and disposable tips. To use a pipette, first rotate the volume adjustment button until the desired volume number appears in the volume display window, then stop rotating. Insert a disposable tip into the lower end of the pipette tip to begin transferring the liquid sample. After completing the transfer, press the tip release button to remove the used disposable tip.

[0003] Disposable pipette tips are typically placed vertically in a dedicated container with the pointed end facing down and the wider end facing up. The container contains a neatly arranged, perforated tray to hold multiple tips. However, inserting a disposable tip into the pipette tip requires opening the container lid, exposing unused tips to air and making them susceptible to dust and other contaminants, thus affecting usability. Furthermore, poor contact during tip insertion can occur due to misalignment or uneven force, requiring repeated pressing and twisting to ensure airtightness. This makes the process less convenient, especially for frequently used multi-channel pipettes, significantly increasing the operator's workload. Summary of the Invention

[0004] The purpose of this invention is to provide a pipette with a tip feeding device, which can realize automatic tip loading and unloading, reduce the labor intensity of the operator, improve the pipetting efficiency, and avoid tip contamination from the outside.

[0005] To achieve the above objectives, the technical solution adopted by the present invention is as follows: a pipette with a tip feeding device, comprising a pipette body, a tip feeding device, and a feeding device driving mechanism. The feeding device driving mechanism is disposed beside the pipette body, and the tip feeding device is fixedly installed at the lower end of the feeding device driving mechanism. The tip feeding device includes a feeding device housing, a tip pushing device disposed therein, and multiple tips arranged in sequence. The feeding device housing has a vertically penetrating tip outlet through hole, through which a pipette piston cylinder at the lower part of the pipette body passes. The tip pushing device pushes the tip toward the tip outlet through hole. The feeding device driving mechanism drives the tip feeding device to move up and down to fit the tip onto the pipette nozzle at the lower end of the pipette piston cylinder. The lower inner side of the feeding device housing is provided with a release pin to lock the tip on the pipette nozzle and separate it from the pipette nozzle when the tip feeding device moves downward.

[0006] Furthermore, the ammunition feeding mechanism is a hand-operated mechanism, which includes a mounting frame, a pressing part, a push rod, and a return spring. The mounting frame is fixedly connected to the side of the pipette body. The push rod is installed inside the mounting frame and can move up and down. Several limiting guide sleeves are arranged vertically on the inner side of the mounting frame to guide the movement of the push rod. The upper end of the push rod is fixedly connected to the pressing part, and the lower end of the push rod is fixedly connected to the suction tip ammunition feeding device. The return spring is installed between the pressing part and the uppermost limiting guide sleeve to drive the push rod to return to its original position after it moves downward.

[0007] Furthermore, the feeding device drive mechanism is an electrically controlled drive mechanism, which includes a mounting frame, a power supply battery, a motor, a lead screw, an electric push rod, and a motor control button. The mounting frame is fixedly connected to the side of the pipette body. The power supply battery and the motor are fixedly installed inside the mounting frame, and the output end of the motor is connected downward to the lead screw to drive the lead screw to rotate. The lower part of the lead screw cooperates with the electric push rod to drive the electric push rod to move up and down through the forward and reverse rotation of the lead screw. The lower end of the electric push rod is fixedly connected to the upper end of the top rod, and the lower end of the top rod is fixedly connected to the pipette feeding device. The power supply battery supplies power to the motor, and the motor control button is connected to the control end of the motor to control the start, stop, forward and reverse rotation of the motor.

[0008] Furthermore, the suction head ammunition supply device includes a suction head ammunition magazine, a suction head ammunition cylinder, a suction head ammunition drum, a suction head spiral ammunition drum, a suction head ammunition disc, a suction head ammunition belt, a suction head ammunition plate, a suction head ammunition chain, a suction head ammunition nest, a suction head ammunition box, a suction head ammunition hopper, and a suction head ammunition clip.

[0009] Furthermore, the main body of the pipette includes a housing, a control button, a counter, a volume adjustment button, a volume display window, a pipette piston rod, and a pipette piston cylinder.

[0010] Furthermore, the main body of the pipette is a single-channel pipette body, and the inner shell of the feeding device is provided with a single pipette tip pushing device and a single row of pipette tips. The outer shell of the feeding device is provided with a single vertically penetrating pipette tip outlet through hole.

[0011] Furthermore, the tip feeder is a tip drum, which includes a tip drum shell and multiple tips, a coiled spring, and a pusher slider disposed therein. The tip drum shell has a guide partition inside to allow the multiple tips to be arranged sequentially and regularly inside the tip drum shell. One end of the coiled spring is fixedly connected to the tip drum shell, and the other end is fixedly connected to the pusher slider. The pusher slider pushes the regularly arranged multiple tips along the guide partition from the rear to the tip outlet through hole. A wedge-shaped release pin is provided on the lower inner side of the tip drum, with the tip tip facing down and the coarse tip facing up, so that the tip can pass smoothly when the tip drum moves upward, and when the tip drum moves downward, it can lock the upper end of the tip on the pipette tip and separate it from the pipette tip.

[0012] Furthermore, the pipette body is a multi-channel pipette body. The lower part of the multi-channel pipette body includes a piston mechanism housing, a drive rod, a piston push plate, multiple pipette piston rods, and multiple pipette piston cylinders. The multiple pipette piston cylinders are installed side by side in the piston mechanism housing and extend downward out of the piston mechanism housing. The lower end of the drive rod is fixedly connected to the upper part of the piston push plate. The lower part of the piston push plate is fixedly connected to the multiple pipette piston rods arranged side by side in the piston mechanism housing. The multiple pipette piston rods cooperate with the corresponding pipette piston cylinders. The multi-channel pipette body drives the piston push plate and the multiple pipette piston rods below it to move up and down through the drive rod. The feed cartridge housing is provided with multiple tip pushing devices and multiple rows of tips. The feed cartridge housing is provided with multiple vertically penetrating tip outlet holes. The multiple tip pushing devices push the corresponding rows of tips into the corresponding tip outlet holes. The lower inner side of the feed cartridge housing is provided with multiple release pins corresponding to the multiple tip outlet holes.

[0013] Furthermore, the suction head feeding device is a multi-channel suction head magazine. The multi-channel suction head magazine includes a multi-channel magazine housing and multiple suction heads, multiple suction head push springs, and multiple suction head push plates disposed therein. Multiple suction head magazine partitions are arranged side-by-side inside the multi-channel magazine housing to divide the interior of the housing into multiple suction head conveying channels. Each suction head conveying channel contains multiple suction heads arranged regularly and is equipped with suction head push springs and suction head push plates. Each suction head conveying channel has a through-hole at its front end. One end of the tip pusher spring is fixedly connected to the outer shell of the multi-channel tip magazine, and the other end is fixedly connected to the tip pusher plate. The tip pusher plate pushes multiple regularly arranged tips along the tip delivery channel from the rear to the tip outlet through hole. The lower inner side of the multi-channel tip magazine is provided with multiple wedge-shaped release pins corresponding to the multiple tip delivery channels. The tip tip points downward and the coarse tip points upward, so that the tip can pass smoothly when the multi-channel tip magazine moves upward, and when the multi-channel tip magazine moves downward, it can lock the upper end of the tip on the pipette tip and separate it from the pipette tip.

[0014] Compared with the prior art, the present invention has the following beneficial effects: The present invention provides a pipette with a tip feeder, which can store multiple tips in its built-in tip feeder and achieve automatic installation and removal of tips through the cooperation of the tip feeder and the pipette body. This not only reduces the labor intensity of the operator and improves the pipetting efficiency, but also avoids the tip from being contaminated by the outside world. It has strong practicality and broad application prospects. Attached Figure Description

[0015] Figure 1 This is a front view of the single-channel pipette with a suction tip drum in Embodiment 1 of the present invention;

[0016] Figure 2 This is a rear view of the single-channel pipette with a tip drum in Embodiment 1 of the present invention;

[0017] Figure 3 This is a side view of a single-channel pipette with a tip drum according to Embodiment 1 of the present invention;

[0018] Figure 4 for Figure 3 AA section view;

[0019] Figure 5 This is a top view of the single-channel pipette with a suction tip drum in Embodiment 1 of the present invention;

[0020] Figure 6 This is a partial cross-sectional view of a single-channel pipette with a tip drum in its initial state according to Embodiment 1 of the present invention;

[0021] Figure 7 This is a partial cross-sectional view of a single-channel pipette with a suction tip drum during compression in Embodiment 1 of the present invention;

[0022] Figure 8 This is a partial cross-sectional view of a single-channel pipette with a suction tip drum when the hand-controlled drive mechanism is fully compressed in Embodiment 1 of the present invention;

[0023] Figure 9 This is a partial cross-sectional view of a single-channel pipette with a suction tip drum when the manual drive mechanism of Embodiment 1 of the present invention rebounds.

[0024] Figure 10 This is a partial cross-sectional view of a single-channel pipette with a suction tip drum when the hand-controlled drive mechanism has fully rebounded in Embodiment 1 of the present invention;

[0025] Figure 11 This is a partial cross-sectional view of a single-channel pipette with a suction tip drum when the hand-controlled drive mechanism is partially compressed again in Embodiment 1 of the present invention;

[0026] Figure 12 A front view of an existing multichannel pipette;

[0027] Figure 13 This is a front view of a multi-channel pipette with a multi-channel tip cartridge according to Embodiment 2 of the present invention;

[0028] Figure 14 This is a rear view of a multi-channel pipette with a multi-channel tip cartridge according to Embodiment 2 of the present invention;

[0029] Figure 15 This is a partial cross-sectional view of a multi-channel pipette with a multi-channel tip cartridge in Embodiment 2 of the present invention;

[0030] Figure 16 This is a side view of a multi-channel pipette with a multi-channel tip cartridge according to Embodiment 2 of the present invention;

[0031] Figure 17 for Figure 16 BB cross-sectional view;

[0032] Figure 18 This is a partial cross-sectional view of a multichannel pipette with a multichannel tip cartridge in its initial state according to Embodiment 2 of the present invention;

[0033] Figure 19 This is a partial cross-sectional view of a multi-channel pipette with a multi-channel suction tip magazine during compression in Embodiment 2 of the present invention;

[0034] Figure 20 This is a partial cross-sectional view of a multi-channel pipette with a multi-channel tip magazine when the hand-controlled drive mechanism is fully compressed in Embodiment 2 of the present invention;

[0035] Figure 21 This is a partial cross-sectional view of a multi-channel pipette with a multi-channel suction tip magazine during the partial rebound of the hand-controlled drive mechanism in Embodiment 2 of the present invention;

[0036] Figure 22 This is a partial cross-sectional view of a multi-channel pipette with a multi-channel tip magazine when the hand-controlled drive mechanism has fully rebounded in Embodiment 2 of the present invention;

[0037] Figure 23 This is a partial cross-sectional view of a multi-channel pipette with a multi-channel tip magazine when the hand-controlled drive mechanism is partially compressed again in Embodiment 2 of the present invention;

[0038] Figure 24 This is a partial cross-sectional view of a single-channel pipette with an electrically controlled driven tip drum in the initial state according to Embodiment 3 of the present invention;

[0039] Figure 25 This is a partial cross-sectional view of a single-channel pipette when the electrically controlled drive mechanism is fully extended in Embodiment 3 of the present invention;

[0040] Figure 26 This is a partial cross-sectional view of the single-channel pipette when the electrically controlled drive mechanism is fully retracted in Embodiment 3 of the present invention;

[0041] Figure 27 This is a partial cross-sectional view of the single-channel pipette when the electrically controlled drive mechanism partially extends again in Embodiment 3 of the present invention.

[0042] In the diagram: 1-Single-channel pipette body, 2-Tip spring, 3-Control button, 4-Volume adjustment button, 5-Volume display window, 6-Pipette piston cylinder, 7-Pipette tip, 8-Pressing part, 9-Push rod, 10-Reset spring, 11-Spring washer, 12-Tip spring housing, 13-Tip, 14-Guide partition, 15-Rolled spring, 16-Push slider, 17-Release pin, 18-Limit guide sleeve, 19-Fixing bolt, 20-Multi-channel pipette body, 21-Lower part of multi-channel pipette body, 2 2-Piston mechanism housing, 23-Multi-channel pipette tip magazine, 24-Multi-channel pipette tip magazine outer shell, 25-Multi-channel pipette tip, 26-Drive rod, 27-Piston push plate, 28-Card slot, 29-Pipette piston rod, 30-Fixing groove, 31-Pipette piston cylinder, 32-Pipette tip magazine partition, 33-Magazine spring washer, 34-Pipette tip push plate, 35-Pipette tip push spring, 36-Single-channel pipette body, 37-Motor control button, 38-Power supply battery, 39-Motor, 40-Electric push rod, 41-Lead screw. Detailed Implementation

[0043] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0044] It should be noted that the following detailed descriptions are exemplary and intended to provide further explanation of this application. Unless otherwise specified, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains.

[0045] It should be noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the exemplary embodiments according to this application. As used herein, the singular form is intended to include the plural form as well, unless the context clearly indicates otherwise. Furthermore, it should be understood that when the terms "comprising" and / or "including" are used in this specification, they indicate the presence of features, steps, operations, devices, components, and / or combinations thereof.

[0046] like Figure 1-11As shown, the present invention provides a pipette with a tip feeding device, comprising a pipette body 1, a tip feeding device 2, and a feeding device driving mechanism. The feeding device driving mechanism is disposed beside the pipette body 1, and the tip feeding device 2 is fixedly installed at the lower end of the feeding device driving mechanism. The tip feeding device 2 includes a feeding device housing 12, a tip pushing device disposed therein, and a plurality of tips 13 arranged in sequence. The feeding device housing 12 has a tip outlet that extends vertically through the pipette body. The pipette piston cylinder 6, located at the lower part of the pipette body 1, passes through the through hole. The pipette tip pushing device pushes the pipette tip 13 toward the pipette tip outlet through hole. The feeding device driving mechanism drives the pipette tip feeding device 2 to move up and down, so as to put the pipette tip 13 onto the pipette tip 7 at the lower end of the pipette piston cylinder 6. The lower part of the inner side of the feeding device housing 12 is provided with a release pin 17, so as to lock the pipette tip 13 on the pipette tip 7 when the pipette tip feeding device 2 moves downward, thereby separating it from the pipette tip 7.

[0047] The ammunition feeding drive mechanism can be a manually controlled drive mechanism or an electronically controlled drive mechanism.

[0048] like Figure 6-11 As shown, in Embodiment 1, the ammunition feeding mechanism is a hand-operated mechanism, which includes a mounting frame, a pressing part 8, a push rod 9, and a return spring 10. The mounting frame is fixedly connected to the side of the pipette body 1. The push rod 9 is installed in the mounting frame and can move up and down. Several limiting guide sleeves 18 are arranged vertically on the inner side of the mounting frame to guide the movement of the push rod 9. The upper end of the push rod 9 is fixedly connected to the pressing part 8, and the lower end of the push rod 9 is fixedly connected to the suction tip ammunition feeding device. The return spring 10 is installed between the pressing part 8 and the uppermost limiting guide sleeve 18 (a spring washer 11 is provided between the return spring 10 and the pressing part 8) to drive the push rod to return to its original position after it moves downward.

[0049] like Figure 24-27 As shown in Embodiment 3, the ammunition feeding mechanism is an electrically controlled drive mechanism, which includes a mounting frame, a power supply battery 38, a motor 39, a lead screw 41, an electric push rod 40, and a motor control button 37. The mounting frame is fixedly connected to the side of the pipette body 36. The power supply battery 38 and the motor 39 are fixedly installed inside the mounting frame, and the output end of the motor 39 is connected downward to the lead screw 41 to drive the lead screw 41 to rotate. The lower part of the lead screw 41 cooperates with the electric push rod 40 to drive the electric push rod 40 to move up and down through the forward and reverse rotation of the lead screw 41. The lower end of the electric push rod 40 is fixedly connected to the upper end of the top rod 9, and the lower end of the top rod 9 is fixedly connected to the suction tip ammunition feeding device. The power supply battery 38 supplies power to the motor 39, and the motor control button 37 is connected to the control end of the motor 39 to control the motor's start, stop, forward and reverse rotation.

[0050] The suction head ammunition feeding device can be implemented in various structural forms, including but not limited to suction head ammunition magazine, suction head ammunition cylinder, suction head ammunition drum, suction head spiral ammunition drum, suction head ammunition disc, suction head ammunition belt, suction head ammunition plate, suction head ammunition chain, suction head ammunition nest, suction head ammunition box, suction head ammunition hopper, suction head ammunition clip, etc.

[0051] The pipette body can be a single-channel pipette body or a multi-channel pipette body.

[0052] like Figure 1-11 As shown, in Embodiment 1, the pipette body is a single-channel pipette body 1, and the tip feeder is a tip drum 2. The single-channel pipette body 1 mainly includes a housing, a control button 3, a counter, a volume adjustment button 4, a volume display window 5, a pipette piston rod, and a pipette piston cylinder 6. The tip drum 2 includes a tip drum shell 12 and multiple tips 13, a coiled spring 15, and a pusher slider 16 disposed therein. The tip drum shell 12 has a single tip pusher device and a single row of tips, and the feeder shell has a single vertically penetrating tip outlet through hole. The pipette tip drum housing 12 is provided with a guide baffle 14 to allow multiple pipette tips 13 to be arranged sequentially and regularly inside the pipette tip drum housing 12. One end of the coiled spring 15 is fixedly connected to the pipette tip drum housing 12, and the other end is fixedly connected to the push slider 16. The push slider 16 pushes the regularly arranged multiple pipette tips 13 along the guide baffle 14 from the rear to the pipette tip outlet through hole. The lower inner side of the pipette tip drum is provided with a wedge-shaped release pin 17, with the tip of the pipette tip facing down and the coarse end facing up, so that the pipette tip can pass smoothly when the pipette tip drum moves upward, and when the pipette tip drum moves downward, it can lock the upper end of the pipette tip on the pipette tip and separate it from the pipette tip.

[0053] like Figure 13-23As shown, in Embodiment 2, the pipette body is a multi-channel pipette body 20, and the tip feeder is a multi-channel tip magazine 23. Besides including a housing, control button 3, counter, volume adjustment button 4, and volume display window 5, the lower part 21 of the multi-channel pipette body 20 also includes a piston mechanism housing 22, a drive rod 26, a piston pusher plate 27, multiple pipette piston rods 29, and multiple pipette piston cylinders 31. The multiple pipette piston cylinders 31 are installed side-by-side inside the piston mechanism housing 22 and pass downwards through a fixing groove 30 on the lower end face of the piston mechanism housing. The lower end of the drive rod 26 is fixedly connected to the upper part of the piston pusher plate 27, and the lower part of the piston pusher plate 27 is arranged side-by-side inside the piston mechanism housing. Multiple pipette piston rods 29 are fixedly connected, and each of the multiple pipette piston rods 29 cooperates with a corresponding pipette piston cylinder 31. The multi-channel pipette body drives the piston push plate and the multiple pipette piston rods below it to move up and down through a drive rod. The feed container housing is provided with multiple tip pushing devices and multiple rows of tips. The feed container housing is provided with multiple vertically penetrating tip outlet holes. The multiple tip pushing devices push the corresponding rows of tips into the corresponding tip outlet holes. The lower inner side of the feed container housing is provided with multiple release pins corresponding to the multiple tip outlet holes. The multi-channel suction head magazine 23 includes a multi-channel suction head magazine housing 24 and multiple suction heads 13, multiple suction head push springs 35, and multiple suction head push plates 34 disposed therein. Multiple suction head magazine partitions 32 are arranged side-by-side inside the multi-channel suction head magazine housing 24 to divide the interior of the housing into multiple suction head conveying channels. Multiple suction heads 13 are regularly arranged in each suction head conveying channel, and each channel is equipped with a suction head push spring 35 and a suction head push plate 34. Each suction head conveying channel has a through-hole at its front end. One end of each suction head push spring 35 is connected to the multi-channel suction head magazine housing 24. A fixed connection is provided (a magazine spring washer 33 is provided between the tip push spring 35 and the multi-channel tip magazine housing 24), and the other end is fixedly connected to the tip push plate 34. The tip push plate pushes multiple regularly arranged tips along the tip delivery channel from the rear to the tip outlet through hole. The lower inner side of the multi-channel tip magazine is provided with multiple wedge-shaped release pins corresponding to the multiple tip delivery channels. The tip tip points downward and the coarse tip points upward, so that the tip can pass smoothly when the multi-channel tip magazine moves upward, and when the multi-channel tip magazine moves downward, it can lock the upper end of the tip on the pipette tip and separate it from the pipette tip.

[0054] The implementation of the pipette with a suction tip feeding device proposed in this invention will be further explained below based on Examples 1, 2, and 3.

[0055] Example 1

[0056] This embodiment provides a single-channel pipette with a tip drum, including a single-channel pipette body 1, a tip drum 2, and a tip feeding drive mechanism. For example... Figure 1 , Figure 2 , Figure 3 , Figure 5 and Figure 6 As shown, the pipette body 1 includes a housing, a control button 3, a counter, a volume adjustment button 4, a volume display window 5, a pipette piston rod, a pipette piston cylinder 6, and a pipette tip 7. The tip-driven mechanism includes a pressing part 8, a push rod 9, a return spring 10, a spring washer 11, a limiting guide sleeve 18, and a fixing bolt 19. The push rod 9 is connected to the tip drum housing 12 (tip drum 2) via the fixing bolt 19. Pressing the pressing part 8 moves the tip drum housing 12 (tip drum 2) downwards via the push rod 9, and the limiting guide sleeve 18 ensures that the push rod 9 and the tip drum 2 do not deviate during movement. Conversely, releasing the pressing part 8 causes the push rod 9 to move upwards under the restoring force of the return spring 10.

[0057] like Figure 4 and Figure 6 As shown, the suction head drum 2 includes a suction head drum housing 12, suction heads 13, a guide partition 14, a coiled spring 15, a push slider 16, and a release pin 17. The suction head drum 2 is filled with multiple suction heads 13 arranged vertically with their pointed ends facing down and their wider ends facing up. Under the elastic force of the coiled spring 15, the push slider 16 pushes these suction heads 13 forward along the channel formed by the suction head drum housing 12 and the guide partition 14.

[0058] like Figure 3 , Figure 6 and Figure 7 As shown, when the pipette is pressed down on the pressing part 8, the push rod 9 drives the tip drum housing 12 (tip drum 2) to move downwards and separate from the pipette piston cylinder 6, while the return spring 10 is compressed. When the tip drum housing 12 (tip drum 2) descends to almost leave the pipette tip 7 (as shown), Figure 8 When the push slider 16 is released, the spring force of the coiled spring 15 pushes the pipette tip 13 to the space directly below the pipette nozzle 7, i.e., the space vacated by the pipette piston cylinder 6. Releasing the pressing part 8 and the push rod 9, under the restoring force of the return spring 10, causes the pipette tip drum housing 12 (pipette tip drum 2) to move upwards (as shown). Figure 9 During this process, the suction nozzle 7 is inserted into the upper end of the suction head 13 and tightly joined under the action of friction around it. When the suction head drum 2 (suction head drum shell 12) moves upward to its initial position (e.g. Figure 10The pipette tip is now installed and pipetting can begin. Observe the volume display window 5, rotate the volume adjustment button 4 to the desired number, insert the tip of pipette tip 13 below the surface of the liquid to be collected, press the control button 3 to expel air, and then release it. The liquid is drawn into the pipette tip 13. After aspiration, remove the pipette tip 13 and insert it into another container, then press the control button 3 to expel the liquid. After pipetting, press the pressing part 8 again. The tip spring housing 12 (tip spring 2) and the release pin 17 on the inner wall move downward together. The tip 7 with tip 13 separates when it touches the release pin 17 (e.g., ...). Figure 11 The pipette tip 13 is then detached. The pipette of this invention achieves automatic installation and detachment of the pipette tip 13 through the operation of the pressing part 8 and the tip spring drum 2.

[0059] Example 2

[0060] This embodiment provides a multichannel pipette with a tip cartridge, which differs from ordinary multichannel pipettes (such as...). Figure 12 It includes a multi-channel pipette body 20, a multi-channel pipette tip magazine 23, and a feeding mechanism. For example... Figure 13 , Figure 14 , Figure 15 , Figure 16 and Figure 18 As shown, the multichannel pipette body 20 includes a housing, control button 3, counter, volume adjustment button 4, volume display window 5, etc. The lower part 21 of the multichannel pipette body includes a piston mechanism housing 22, multichannel pipette tip 25, drive rod 26, piston push plate 27, multichannel pipette piston rod 29, multichannel pipette piston cylinder 31, etc. The cartridge drive mechanism includes a pressing part 8, push rod 9, return spring 10, spring washer 11, limit guide sleeve 18, and fixing bolt 19. Figure 17 and Figure 18 As shown, the multi-channel suction head magazine 23 includes a multi-channel suction head magazine housing 24, suction heads 13, a release pin 17, a suction head magazine partition 32, a magazine spring washer 33, a suction head pusher plate 34, and a suction head pusher spring 35. Each channel of the multi-channel suction head magazine 23 contains multiple suction heads 13 arranged vertically with their pointed ends facing downwards and their wider ends facing upwards. Under the elastic force of the suction head pusher spring 35, the suction head pusher plate 34 pushes these suction heads 13 forward along the channel formed by the suction head magazine partition 32.

[0061] like Figure 15 , Figure 16 , Figure 18 and Figure 19As shown, when the multichannel pipette is pressed down on the pressing part 8, the push rod 9 drives the multichannel tip magazine housing 24 (multichannel tip magazine 23) to move downwards and separate from the multichannel pipette piston cylinder 31, while the return spring 10 is compressed. When the multichannel tip magazine housing 24 (multichannel tip magazine 23) descends to almost leave the multichannel pipette tip 25 (e.g., ... Figure 20 When the pipette tip pusher plate 34 pushes the entire row of pipette tips 13 to the space directly below the multi-channel pipette tip 25, i.e., the space vacated by the multi-channel pipette piston cylinder 31, through the elastic force of the pipette tip pusher spring 35. Releasing the pusher rod 9 of the pressing part 8, under the restoring force of the return spring 10, causes the multi-channel pipette tip magazine housing 24 (multi-channel pipette tip magazine 23) to move upwards (e.g., ...). Figure 21 During this process, the multi-channel pipette tips 25 are inserted into the upper end of the pipette tip 13 in a row and tightly joined by the friction around them. When the multi-channel pipette tip magazine housing 24 (multi-channel pipette tip magazine 23) moves upward to the initial position (e.g. Figure 22 The pipette tip has been installed and pipetting can begin.

[0062] Observe the volume display window 5, rotate the volume adjustment button 4 to the desired number, and insert the tip of the pipette tip 13 below the surface of the liquid to be collected. Press the control button 3, and the drive rod 26, connected to the piston push plate 27, will move the entire row of piston rods 29 downwards (e.g., Figure 15 After expelling air, release the button, and the liquid is drawn into the pipette tip 13. After aspiration, remove the tip and insert it into another container. Press the control button 3 to expel the liquid. After pipetting, press the press button 8 again, and the multi-channel tip magazine housing 24 (multi-channel tip magazine 23) and the release pin 17 on the inner wall move downwards together. The multi-channel pipette tip 25 with the entire row of tips 13 separates when it encounters the release pin 17 (e.g., ...). Figure 23 ), suction head 13 is detached, and one cycle is completed.

[0063] Example 3

[0064] This embodiment provides a single-channel pipette with an electrically controlled driven tip cartridge. The difference between this pipette and the pipette in Example 1 is that it uses an electrically controlled drive mechanism instead of a manually controlled drive mechanism. For example... Figure 24 , Figure 25 , Figure 26 and Figure 27 As shown, the electronically controlled drive mechanism includes a motor control button 37, a power supply battery 38, a motor 39, an electric push rod 40, a lead screw 41, a push rod 9, etc.

[0065] When the motor control button 37 is pressed, the motor 39 is energized and begins to rotate the lead screw 41. The connected push rod 9 and the tip drum housing 12 (tip drum 2) move downwards, separating from the pipette piston cylinder 6. When the tip drum housing 12 (tip drum 2) descends to almost leave the pipette tip 7 (as shown in the image),... Figure 25 When pushing slider 16 (e.g.) Figure 4 The spring force of the coiled spring 15 pushes the pipette tip 13 into the space directly below the pipette nozzle 7, i.e., the space vacated by the pipette piston cylinder 6. Pressing the motor control button 37 energizes the motor 39, causing the lead screw 41 to reverse, and the connected push rod 9 and the pipette tip drum housing 12 (pipette tip drum 2) to move upwards. During this process, the pipette nozzle 7 inserts into the upper end of the pipette tip 13 and is tightly engaged by the surrounding friction. When the pipette tip drum 2 (pipette tip drum housing 12) moves upwards to its initial position (e.g....), Figure 26 The pipette tip is now installed and pipetting can begin. After pipetting is complete, press the motor control button 37 again. The pipette tip drum housing 12 (pipette tip drum 2) and the release pin 17 on the inner wall move downwards together. The pipette tip 7 with the tip 13 separates when it touches the release pin 17 (e.g., Figure 27 The pipette tip 13 is detached, completing one cycle. The electrically controlled drive mechanism in the single-channel pipette with electrically controlled pipette tip cartridge mentioned in this embodiment can also be applied to multi-channel pipettes with pipette tip cartridges.

[0066] The above description is merely a preferred embodiment of the present invention and is not intended to limit the invention in any other way. Any person skilled in the art may make changes or modifications to the above-disclosed technical content to create equivalent embodiments. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present invention without departing from the scope of the present invention shall still fall within the protection scope of the present invention.

Claims

1. A pipette with a tip supply, characterized in that The pipette body, the tip supply device and the tip supply device driving mechanism, the tip supply device is fixedly installed at the lower end of the tip supply device driving mechanism, the tip supply device includes a tip supply device shell, a tip pushing device and a plurality of tips arranged in sequence, the tip supply device shell is provided with a tip outlet through hole penetrating from top to bottom, and the pipette piston cylinder of the lower part of the pipette body penetrates through the tip outlet through hole, the tip pushing device pushes the tips to the tip outlet through hole, the tip supply device driving mechanism drives the tip supply device to move downward to make the tips cover the pipette nozzle at the lower end of the pipette piston cylinder, and the tip supply device shell is provided with a dismounting pin at the inner lower part to clamp the tips on the pipette nozzle to separate the tips from the pipette nozzle when the tip supply device moves downward.

2. A pipette with a tip supply according to claim 1, characterized in that The tip supply device driving mechanism is a hand control driving mechanism, which includes a mounting frame, a pressing part, a top rod and a reset spring, the mounting frame is fixedly connected to the side of the pipette body, the top rod is installed in the mounting frame and can move up and down, a plurality of limiting guide sleeves are vertically arranged on the inner side of the mounting frame to guide the movement of the top rod, the upper end of the top rod is fixedly connected with the pressing part, the lower end of the top rod is fixedly connected with the tip supply device, and the reset spring is installed between the pressing part and the uppermost limiting guide sleeve to drive the top rod to reset after moving downward.

3. A pipette with a tip supply according to claim 1, characterized in that The tip supply device driving mechanism is an electric control driving mechanism, which includes a mounting frame, a power supply battery, a motor, a screw rod, an electric push rod and a motor control button, the mounting frame is fixedly connected to the side of the pipette body, the power supply battery and the motor are fixedly installed in the mounting frame, the output end of the motor is downwardly connected with the screw rod to drive the screw rod to rotate, the lower part of the screw rod is matched with the electric push rod to drive the electric push rod to move up and down through the forward and reverse rotation of the screw rod, the lower end of the electric push rod is fixedly connected with the upper end of the top rod, and the lower end of the top rod is fixedly connected with the tip supply device; the power supply battery supplies power for the motor, and the motor control button is connected with the control end of the motor to control the start and stop and the forward and reverse rotation of the motor.

4. The pipette with a tip supply according to claim 1, wherein, The tip supply device includes a tip magazine, a tip clip, a tip drum, a tip spiral drum, a tip disc, a tip belt, a tip plate, a tip chain, a tip nest, a tip box, a tip hopper and a tip clip.

5. The pipette with a tip supply according to claim 1, wherein, The pipette body mainly includes a shell, a control button, a counter, a volume adjustment button, a volume display window, a pipette piston rod and a pipette piston cylinder.

6. A pipettor with a tip supply according to claim 1, wherein, The pipette body is a single-channel pipette body, a single tip pushing device and a single row of tips are correspondingly arranged in the tip supply device shell, and a single tip outlet through hole penetrating from top to bottom is correspondingly formed in the tip supply device shell.

7. The pipette with a tip supply according to claim 1, wherein, The tip supply device is a tip drum, which comprises a tip drum shell, a plurality of tips, a coil spring and a push slider arranged in the tip drum shell, a guide partition plate is arranged in the tip drum shell to arrange the plurality of tips in the tip drum shell in order, one end of the coil spring is fixedly connected with the tip drum shell, and the other end is fixedly connected with the push slider, the push slider pushes the plurality of tips arranged in order along the guide partition plate from the back to the tip outlet through hole, a wedge-shaped disengaging pin is arranged at the lower part of the inner side of the tip drum, the tip has a sharp end and a thick end, the sharp end faces downward, and the thick end faces upward, so that the tip can smoothly pass through the tip drum when the tip drum moves upward, and the tip can be separated from the pipette nozzle when the tip drum moves downward.

8. The pipette with a tip supply according to claim 1, wherein, The pipette body is a multi-channel pipette body, which comprises a piston mechanism shell, a driving rod, a piston push plate, a plurality of pipette piston rods and a plurality of pipette piston cylinders, the plurality of pipette piston cylinders are installed side by side in the piston mechanism shell and downwardly pass through the piston mechanism shell, the lower end of the driving rod is fixedly connected with the upper part of the piston push plate, the lower part of the piston push plate is fixedly connected with the plurality of pipette piston rods arranged side by side in the piston mechanism shell, the plurality of pipette piston rods are respectively matched with the corresponding pipette piston cylinders, and the multi-channel pipette body drives the piston push plate and the plurality of pipette piston rods below the piston push plate to move upward through the driving rod.

9. A pipette with a tip supply according to claim 8, characterized in that The tip supply device is a multi-channel tip drum, which comprises a multi-channel tip drum shell, a plurality of tips, a plurality of tip pushing springs and a plurality of tip pushing plates, a plurality of tip drum partition plates are arranged side by side in the multi-channel tip drum shell to divide the multi-channel tip drum shell into a plurality of tip conveying channels, a plurality of tips are arranged in each tip conveying channel in order and are provided with a tip pushing spring and a tip pushing plate, a tip outlet through hole is arranged at the front end of each tip conveying channel, one end of the tip pushing spring is fixedly connected with the multi-channel tip drum shell, and the other end is fixedly connected with the tip pushing plate, the tip pushing plate pushes the plurality of tips arranged in order along the tip conveying channel from the back to the tip outlet through hole, and a plurality of wedge-shaped disengaging pins are arranged at the lower part of the inner side of the multi-channel tip drum corresponding to the plurality of tip conveying channels, the tip has a sharp end and a thick end, the sharp end faces downward, and the thick end faces upward, so that the tip can smoothly pass through the multi-channel tip drum when the multi-channel tip drum moves upward, and the tip can be separated from the pipette nozzle when the multi-channel tip drum moves downward.

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