A sampling device for detecting liquid medicine in a liquid medicine preparation tank in a biological laboratory

Abstract

The present invention relates to the technical field of liquid medicine sampling, and discloses a sampling device for detecting liquid medicine in a liquid preparation tank in a biological laboratory, which includes a plurality of support rods, a liquid preparation tank arranged between the plurality of support rods, a rotating shaft rod hermetically and rotatably penetrating through the bottom end of the liquid preparation tank, a driving motor arranged at the lower end of the rotating shaft rod, a plurality of stirring rods arranged on the outer wall of the rotating shaft rod, an inlet interface and an outlet interface arranged at the upper end of the liquid preparation tank, and further includes a sampling unit arranged on the liquid preparation tank. The sampling unit includes a sampling component arranged on the side wall of the liquid preparation tank and a voltage transformation component arranged on the outer wall of the lower end of the liquid preparation tank; by arranging the voltage transformation component, when the driving motor drives the stirring rods to stir and mix, the medicine at the bottom can be input above the liquid preparation tank. When sampling is required, sampling can be completed without contacting the medicine inside the liquid preparation tank with the outside world, ensuring the production quality of the medicine.

Description

Technical Field

[0001] The present invention relates to the technical field of liquid medicine sampling, and particularly relates to a sampling device for detecting liquid medicine in a liquid preparation tank in a biological laboratory. Background Art

[0002] A liquid preparation tank is a device used for preparing and mixing liquid materials of medicines. A liquid preparation tank usually includes a tank body, a stirring system, inlet and outlet interfaces, etc. The main function of the liquid preparation tank is to mix various liquid components according to a specific formula to form a uniform mixture. It can handle liquids with different viscosities and different chemical properties. Sampling from inside the liquid preparation tank is a crucial step in the medicine production process, aiming to ensure the quality and consistency of medicines. During the sampling process, sampling is usually carried out after the medicines are mixed evenly to ensure that the sample can represent the quality of the entire batch. Sampling from the medicine preparation tank can detect the component content and physical properties of the medicines to ensure that the final product meets the quality standards.

[0003] When the current liquid preparation tank stirs the internal medicines, it can only mix them evenly in the horizontal direction. If the internal medicines show a layering phenomenon, effective mixing cannot be achieved, which affects the production quality of the medicines. And during the sampling process, the sampling personnel need to first open the valve at the upper end of the liquid preparation tank, and then use sampling equipment such as (sampling tubes, sampling guns) to sample the internal medicines. However, when using these equipment for sampling, opening the valve will cause the inside of the liquid preparation tank to come into contact with the outside world. During the contact process, impurities in the outside air may contaminate the internal medicines of the liquid preparation tank. And some medicines may need to be kept under anaerobic or light-free conditions during the preparation process (such as oxidation-sensitive medicines like antibiotics or hormones, etc.), which may further lead to contamination and deterioration of the internal medicines, and at the same time increase the difficulty of sampling. Summary of the Invention

[0004] In view of the problem that the internal medicines of the liquid preparation tank come into contact with the outside air during the sampling process in the prior art, resulting in deterioration or contamination, a sampling device for detecting liquid medicine in a liquid preparation tank in a biological laboratory is proposed.

[0005] The present application provides a sampling device for detecting liquid medicine in a liquid preparation tank in a biological laboratory, and its purpose is: by setting a voltage-changing component, when the driving motor drives the stirring rod to stir and mix, the medicines at the bottom can be input above the liquid preparation tank, so that the internal medicines are always in a flowing state in the vertical direction, which can effectively improve the mixing quality of the device. At the same time, when sampling is required, the staff only needs to move the sample rack to insert the interface tube into the sample tube. After the interface tube is inserted into the sample tube, the two are automatically connected. At this time, the voltage-changing component can evenly press the uniformly mixed medicines into multiple sample tubes for sampling, and sampling can be completed without contacting the internal medicines of the liquid preparation tank with the outside world, ensuring the production quality of the medicines.

[0006] The technical solution of the present invention is as follows: A sampling device for detecting liquid medicine in a liquid preparation tank in a biological laboratory, including a plurality of support rods, a liquid preparation tank arranged between the plurality of support rods, a rotating shaft rod hermetically and rotatably penetrating through the bottom end of the liquid preparation tank, a driving motor arranged at the lower end of the rotating shaft rod, a plurality of stirring rods arranged on the outer wall of the rotating shaft rod, an inlet interface and an outlet interface arranged at the upper end of the liquid preparation tank, and further including a sampling unit arranged on the liquid preparation tank. The sampling unit includes a sampling component arranged on the side wall of the liquid preparation tank and a voltage transformation component arranged on the outer wall of the lower end of the liquid preparation tank;

[0007] The sampling component includes a sampling sleeve arranged on the outer side wall of the liquid preparation tank, an upper pipe arranged at the upper end of the sampling sleeve, a lower pipe arranged at the sampling sleeve, a return pipe arranged on the side wall of the upper pipe, a sampling pipe arranged on the side wall of the lower pipe, a connecting pipe arranged between the return pipe and the sampling pipe, slide rails arranged on both side walls of the sampling sleeve, a sample rack slidably arranged between the two slide rails, a plurality of mounting holes opened on the sample rack, sample tubes threadedly arranged on the plurality of mounting holes. One-way valves one with opposite flow directions are installed inside both the upper pipe and the lower pipe. One-way components are installed inside a plurality of the sample tubes. A plurality of cooperation components are installed on the lower wall of the sampling pipe and are matched with the one-way components. A closing component is installed between the sampling pipe and the sample rack. Limit components are installed inside both of the two slide rails;

[0008] The driving end of the driving motor is fixedly connected to the lower end of the rotating shaft rod. The upper end of the upper pipe is fixedly communicated with the upper inner end of the liquid preparation tank. The lower end of the lower pipe is fixedly communicated with the lower inner end of the liquid preparation tank. Both the return pipe and the sampling pipe are located inside the sampling sleeve.

[0009] Further, the one-way component includes a mounting ring one arranged at the upper end opening of the inner part of the sample tube, a middle rod arranged on the mounting ring one, a spring rod arranged on the middle rod, a conical sleeve arranged at the upper end of the mounting ring one, a baffle arranged at the upper end of the spring rod, a plurality of one-way valves two arranged on the baffle. The end face size of the baffle is equal to the end face size of the upper end of the conical sleeve. The baffle is located inside the upper end of the conical sleeve. A limit ring for limiting the upward direction of the baffle is fixedly installed at the upper end of the conical sleeve.

[0010] Further, the cooperation component includes a plurality of interface pipes arranged at the lower end of the sampling pipe, a mounting ring two arranged on the inner wall of the interface pipe, a telescopic spring arranged on the mounting ring two, an isolation plate arranged at the upper end of the telescopic spring, a support plate arranged on the inner wall of the interface pipe, a trigger rod hermetically and slidably penetrating through the support plate, a reset plate arranged on the trigger rod, and a reset spring arranged between the reset plate and the support plate.

[0011] Further, the limiting component includes mounting grooves formed in two slide rails, limiting springs respectively arranged on the inner walls of the two mounting grooves, and limiting blocks arranged at one ends of the limiting springs, and the limiting blocks slide in the mounting grooves.

[0012] Further, push rods are hermetically and slidably penetrated through the lower ends of multiple sample tubes, push plates are fixedly installed at the upper ends of each push rod, the end face shapes and sizes of each push plate are the same as those of the inner wall end faces of the sample tubes, and sealing rings are fixedly sleeved on the side walls of each push plate.

[0013] Further, the closing component includes a rotating rod rotatably installed on the sampling tube, an opening and closing plate arranged on the rotating rod, a square block arranged on the sample rack, a convex rod arranged on the square block, an opening and closing groove formed in the rotating rod, the opening and closing groove is composed of a vertical groove and a spiral groove, the lower end of the rotating rod slidably penetrates through the sample rack, one end of the convex rod is located inside the opening and closing groove, the opening and closing plate is located inside the sampling tube, and the end face size of the opening and closing plate is the same as that of the inner wall end face of the sampling tube.

[0014] Further, the voltage transformation component includes a driving gear arranged on the outer wall of the rotating shaft rod, a driven gear arranged at the lower end of the liquid dispensing tank, a turntable arranged at the lower end of the driven gear, a first shaft rod arranged on the turntable, a piston cylinder arranged at the lower end of the liquid dispensing tank, a piston plate hermetically and slidably arranged on the inner wall of the piston cylinder, a square groove formed in the piston plate, a second shaft rod arranged in the square groove, a pull rod rotatably arranged on the second shaft rod, one end of the pull rod far from the second shaft rod is rotatably connected with the first shaft rod, the end face shape and size of the piston plate are the same as those of the inner wall end face of the piston cylinder, and one end of the piston cylinder is fixedly communicated with the side wall of the lower tube through a short tube.

[0015] Further, a communicating pipe is fixedly installed at the upper end of the liquid dispensing tank, an expansion ball is fixedly communicated with one end of the communicating pipe located inside the liquid dispensing tank, the expansion ball is located above the inside of the liquid dispensing tank, and the inside of the expansion ball is communicated with the outside air through the communicating pipe.

[0016] Further, the outer wall size of the interface pipe is equal to the inner wall size of the sample tube.

[0017] Advantages of the present invention:

[0018] 1. By arranging the voltage transformation component, during the process of the stirring rod in the liquid dispensing tank stirring the medicine, the medicine at the lower end of the liquid dispensing tank can be input above the liquid dispensing tank through the voltage transformation component, realizing the mixing of the medicine in the vertical direction, effectively improving the stirring quality and effect of the liquid dispensing tank on the medicine, and avoiding the problem that the horizontal stirring cannot be evenly stirred due to the stratification of the medicine.

[0019] 2. By setting up a sampling component and a closing component, when a sampler needs to take a sample, he / she only needs to push the sample rack equipped with a sample tube upward. After the interface tube is inserted into the sample tube, the sampling tube and the reflux tube are no longer connected, and the interface tube and the sample tube are automatically connected. At this time, under the action of the voltage-changing component, the uniformly mixed medicine is evenly pressed into multiple sample tubes to complete the sampling, and during the sampling process, the medicine in the liquid distribution tank will not come into contact with the outside world, thus preventing contamination.

[0020] 3. By setting up an expansion ball, when sampling the medicine inside the sealed liquid distribution tank, since the medicine inside the liquid distribution tank decreases during the sampling process and the liquid distribution tank is in a sealed state, the pressure inside the liquid distribution tank will become smaller when the medicine decreases. If the pressure inside the liquid distribution tank is not balanced, it may lead to the inability to take a sample. Therefore, the expansion ball can contract as the pressure decreases to balance the pressure inside the expansion ball, thereby ensuring that the pressure inside the liquid distribution tank is always normal and also ensuring the normal progress of sampling. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 is a first - perspective three - dimensional structure schematic diagram of the present invention;

[0022] Figure 2 is an internal planar structure schematic diagram of the present invention;

[0023] Figure 3 is a working process introduction diagram of the present invention;

[0024] Figure 4 is a sampling component structure schematic diagram of the present invention;

[0025] Figure 5 is of the present invention Figure 4 internal planar schematic diagram;

[0026] Figure 6 is a partial cross - sectional structure schematic diagram of the present invention;

[0027] Figure 7 is a sample tube internal structure schematic diagram of the present invention;

[0028] Figure 8 is a one - way component structure schematic diagram of the present invention;

[0029] Figure 9 is of the present invention Figure 8 structural decomposition schematic diagram;

[0030] Figure 10 is a mating component structure schematic diagram of the present invention;

[0031] Figure 11 is of the present invention Figure 10 enlarged structure schematic diagram at A in;

[0032] Figure 12 Schematic structural diagram of the limit component of the present invention;

[0033] Figure 13 Schematic structural diagram of the voltage conversion component of the present invention;

[0034] Figure 14 of the present invention Figure 13 Schematic plan view.

[0035] In the figure:

[0036] 1. Support rod; 2. Liquid distribution tank; 3. Rotating shaft rod; 4. Driving motor; 5. Stirring rod; 6. Inlet interface; 7. Outlet interface; 8. Sampling sleeve; 9. Upper pipe; 10. Lower pipe; 11. Return pipe; 12. Sampling pipe; 13. Connecting pipe; 14. Slide rail; 15. Sample rack; 16. Sample tube; 17. First mounting ring; 18. Middle rod; 19. Spring rod; 20. Conical sleeve; 21. Baffle; 22. Second check valve; 23. Limit ring; 24. Interface pipe; 25. Second mounting ring; 26. Telescopic spring; 27. Partition board; 28. Support plate; 29. Trigger rod; 30. Reset plate; 31. Reset spring; 32. Limit spring; 33. Limit block; 34. Push rod; 35. Push plate; 36. Rotating rod; 37. Opening and closing plate; 38. Square block; 39. Convex rod; 40. Opening and closing groove; 41. Driving gear; 42. Driven gear; 43. Turntable; 44. First shaft rod; 45. Piston cylinder; 46. Piston plate; 47. Second shaft rod; 48. Pull rod; 49. Connecting pipe; 50. Expansion ball. Specific embodiments

[0037] In order to make the above objects, features and advantages of the present invention more obvious and understandable, the following detailed description of the specific embodiments of the present invention will be given with reference to the accompanying drawings of the specification.

[0038] Example 1, referring to Figures 1 - 3 , Figure 5 and Figures 13 - 14 , which is the first embodiment of the present invention, provides a sampling device for detecting the liquid medicine in the liquid distribution tank of a biological laboratory, including a plurality of support rods 1, a liquid distribution tank 2 fixedly installed between the support rods 1, a rotating shaft rod 3 sealed and rotatably installed through the bottom end of the liquid distribution tank 2, a driving motor 4 fixedly installed at the lower end of the rotating shaft rod 3, a plurality of stirring rods 5 fixedly installed on the outer wall of the rotating shaft rod 3, an inlet interface 6 and an outlet interface 7 fixedly and communicatively installed at the upper end of the liquid distribution tank 2, and further including a sampling unit installed on the liquid distribution tank 2. The sampling unit includes a sampling component installed on the side wall of the liquid distribution tank 2 and a voltage conversion component arranged on the outer wall of the lower end of the liquid distribution tank 2;

[0039] The sampling component includes a sampling sleeve 8 fixedly installed on the outer sidewall of the liquid dispensing tank 2, an upper pipe 9 fixedly installed at the upper end of the sampling sleeve 8, a lower pipe 10 fixedly installed at the lower end of the sampling sleeve 8, a return pipe 11 fixedly installed on the sidewall of the upper pipe 9, a sampling pipe 12 fixedly installed on the sidewall of the lower pipe 10, a connecting pipe 13 fixedly installed between the return pipe 11 and the sampling pipe 12, slide rails 14 fixedly installed on both sidewalls of the sampling sleeve 8, a sample rack 15 slidably installed between the two slide rails 14, a plurality of mounting holes opened on the sample rack 15, sample tubes 16 threadedly installed on the plurality of mounting holes, one-way valves one with opposite flow directions installed inside both the upper pipe 9 and the lower pipe 10, one-way components installed inside each of the plurality of sample tubes 16, a plurality of cooperating components installed on the lower wall of the sampling pipe 12 and cooperating with the one-way components, a closing component installed between the sampling pipe 12 and the sample rack 15, and limiting components installed inside both of the two slide rails 14;

[0040] The driving end of the driving motor 4 is fixedly connected to the lower end of the rotating shaft rod 3. The upper end of the upper pipe 9 is fixedly and communicatively connected to the upper inner end of the liquid dispensing tank 2. The lower end of the lower pipe 10 is fixedly and communicatively connected to the lower inner end of the liquid dispensing tank 2. Both the return pipe 11 and the sampling pipe 12 are located inside the sampling sleeve 8.

[0041] Refer to Figure 13 and Figure 14 , the voltage transformation component includes a driving gear 41 fixedly installed on the outer wall of the rotating shaft rod 3, a driven gear 42 rotatably installed at the lower end of the liquid dispensing tank 2, a turntable 43 fixedly installed at the lower end of the driven gear 42, a first shaft rod 44 fixedly installed on the turntable 43, a piston cylinder 45 fixedly installed at the lower end of the liquid dispensing tank 2, a piston plate 46 sealingly and slidably installed on the inner wall of the piston cylinder 45, a square groove opened on the piston plate 46, a second shaft rod 47 fixedly installed in the square groove, a pull rod 48 rotatably installed on the second shaft rod 47, one end of the pull rod 48 away from the second shaft rod 47 is rotatably connected to the first shaft rod 44. The end face shape and size of the piston plate 46 are the same as those of the inner wall end face of the piston cylinder 45. One end of the piston cylinder 45 is fixedly and communicatively connected to the sidewall of the lower pipe 10 through a short pipe.

[0042] Specifically, when the rotating shaft rod 3 inside the liquid preparation tank 2 rotates to stir the liquid medicine inside, the mixed liquid medicine often undergoes different degrees of stratification due to different densities and masses. When the existing stirring rod 5 stirs the mixed liquid medicine, it can only stir the liquid medicine at the same height in the horizontal direction, but cannot stir the liquid medicine at different heights in the vertical direction. Therefore, an upper pipe 9, a lower pipe 10, a reflux pipe 11, and a sampling pipe 12 are provided on the outer wall of the liquid preparation tank 2. When the rotating shaft rod 3 stirs the mixed liquid medicine, the liquid medicine in the lower area enters the lower pipe 10 under the action of pressure, flows into the sampling pipe 12 through the lower pipe 10, flows into the reflux pipe 11 from the sampling pipe 12 through the connecting pipe 13, and finally flows into the upper area of the liquid preparation tank 2 through the upper pipe 9, so that the lower liquid medicine is continuously mixed with the upper liquid medicine, avoiding the occurrence of insufficient mixing caused by stratification during the stirring process. At the same time, adopting this design can help with subsequent sampling, and can complete the sampling of the internal liquid medicine while preventing the liquid medicine inside the liquid preparation tank 2 from contacting the outside air, greatly improving the production quality and the convenience of sampling.

[0043] The inlet interface 6 and the outlet interface 7 are used for feeding and discharging. There are covers (not shown in the figure) on the inlet interface 6 and the outlet interface 7. The covers are used to ensure that the inlet interface 6 and the outlet interface 7 are in a closed state, so as to ensure that the inside of the liquid preparation tank 2 is always in a closed state when preparing the liquid medicine, and prevent the internal medicine from contacting the outside oxygen and causing deterioration and pollution when preparing some oxidation-sensitive drugs in the liquid preparation tank 2.

[0044] During use, the staff inputs the liquid medicine raw materials to be configured into the liquid preparation tank 2 through the inlet interface 6, closes the cover, turns on the drive motor 4. The drive motor 4 drives the rotating shaft rod 3 to rotate through the drive end. The rotating shaft rod 3 rotates to drive the stirring rod 5 to rotate and stir the liquid medicine inside. While the rotating shaft rod 3 rotates, it drives the driven gear 42 to rotate through the drive gear 41. The driven gear 42 rotates to continuously pull the pull rod 48 to move through the shaft rod one 44 on the turntable 43. The pull rod 48 drives the piston plate 46 to slide reciprocally on the inner wall of the piston cylinder 45 through the shaft rod two 47. As the piston plate 46 slides reciprocally, the pressure inside the piston cylinder 45 changes continuously. When the pressure inside the piston cylinder 45 becomes smaller, the liquid medicine in the lower area of the liquid preparation tank 2 enters the lower pipe 10 through the one-way valve one under the action of pressure. When the pressure inside the piston cylinder 45 becomes larger, the liquid medicine inside the lower pipe 10 enters the upper part of the liquid preparation tank 2 through the upper pipe 9. At this time, the phenomenon of liquid medicine stratification can be prevented, and at the same time, the stirring rod 5 can stir the liquid medicine better when rotating.

[0045] Example 2, refer to Figures 4 - 12, which is the second embodiment of the present invention. The difference between this embodiment and the first embodiment is that the one-way component includes a mounting ring 17 fixedly installed at the upper end of the inner tube mouth of the sample tube 16, a middle rod 18 fixedly installed on the mounting ring 17, a spring rod 19 fixedly installed on the middle rod 18, a tapered sleeve 20 fixedly installed at the upper end of the mounting ring 17, a baffle 21 fixedly installed at the upper end of the spring rod 19, a plurality of check valves 22 fixedly installed on the baffle 21. The end face size of the baffle 21 is equal to the end face size of the upper end of the tapered sleeve 20. The baffle 21 is located inside the upper end of the tapered sleeve 20. A limit ring 23 for limiting the upward direction of the baffle 21 is fixedly installed at the upper end of the tapered sleeve 20.

[0046] The matching component includes a plurality of interface pipes 24 fixedly installed at the lower end of the sampling pipe 12, a mounting ring 25 fixedly installed on the inner wall of the interface pipe 24, a telescopic spring 26 fixedly installed on the mounting ring 25, a partition plate 27 fixedly installed at the upper end of the telescopic spring 26, a support plate 28 fixedly installed on the inner wall of the interface pipe 24, a trigger rod 29 sealingly and slidably penetrating through the support plate 28, a reset plate 30 fixedly installed on the trigger rod 29, and a reset spring 31 fixedly installed between the reset plate 30 and the support plate 28.

[0047] The limit component includes mounting grooves opened on the two slide rails 14, limit springs 32 respectively fixedly installed on the inner walls of the two mounting grooves, and limit blocks 33 fixedly installed at one ends of the limit springs 32. The limit blocks 33 slide in the mounting grooves.

[0048] The lower ends of a plurality of sample tubes 16 are all sealingly and slidably penetrated and installed with push rods 34. A push plate 35 is fixedly installed at the upper end of each push rod 34. The end face shape and size of each push plate 35 are the same as the end face shape and size of the inner wall of the sample tube 16. A sealing ring is fixedly sleeved on the side wall of each push plate 35.

[0049] The closing component includes a rotating rod 36 rotatably installed on the sampling pipe 12, an opening and closing plate 37 fixedly installed on the rotating rod 36, a square block 38 fixedly installed on the sample rack 15, a convex rod 39 fixedly installed on the square block 38, an opening and closing groove 40 opened on the rotating rod 36. The opening and closing groove 40 is composed of a vertical groove and a spiral groove. The lower end of the rotating rod 36 slidably penetrates through the sample rack 15. One end of the convex rod 39 is located inside the opening and closing groove 40. The opening and closing plate 37 is located inside the sampling pipe 12, and the end face size of the opening and closing plate 37 is the same as the end face size of the inner wall of the sampling pipe 12. The outer wall size of the interface pipe 24 is equal to the inner wall size of the sample tube 16.

[0050] Specifically, the one-way component, the mating component, and the closing component are used to sample the liquid medicine inside the liquid dispensing tank 2. The working process is as follows: The staff pushes the sample rack 15 upward, so that the interface pipe 24 is inserted into the sample pipe 16. At this time, the one-way component and the mating component cooperate with each other, so that the sampling pipe 12 is connected to the sample pipe 16 through the interface pipe 24. During the upward movement of the sample rack 15, one end of the sampling pipe 12 is closed by the closing component, so that the sampling pipe 12 is only connected to the sample pipe 16. At this time, under the action of the voltage-changing component, the liquid medicine enters the sample pipe 16 to complete the sampling.

[0051] When the liquid medicine inside the liquid preparation tank 2 is fully and evenly mixed, the staff needs to take samples of the liquid medicine inside it to detect the component content and physical properties of the medicine. Under normal conditions, the interface pipe 24 on the sampling pipe 12 is in a sealed state under the action of the matching component, and multiple sample pipes 16 are also in a sealed state under the action of the one-way component. At this time, during the mixing and stirring process, the liquid medicine in the liquid preparation tank 2 flows into the sampling pipe 12 and then flows into the return pipe 11 under the action of pressure and reflows back into the liquid preparation tank 2. Threaded structures that match each other are provided on the mounting holes on the sample rack 15 and the outer wall of the sample pipe 16, and the two are connected to each other through the threaded structure. When sampling is required, the staff threadedly installs the sample pipe 16 on the sample rack 15 and pushes the sample rack 15 upward. At this time, the interface pipe 24 is inserted into the inner wall of the sample pipe 16, and at the same time, the trigger rod 29 in the interface pipe 24 moves toward the sampling pipe 12 under the thrust of the baffle 21 in the sample pipe 16. At this time, one end of the trigger rod 29 contacts the isolation plate 27 and generates a thrust. The isolation plate 27 moves into the sampling pipe 12 under the action of the thrust. At this time, a gap is generated between the isolation plate 27 and the interface pipe 24. At the same time, when the reset plate 30 moves to fit with the support plate 28, the trigger rod 29 will no longer displace. At this time, the trigger rod 29 generates a reaction force on the baffle 21. At this time, the baffle 21 slides toward the bottom end of the sample pipe 16, and a gap is generated between the baffle 21 and the tapered sleeve 20. At this time, the sample pipe 16 is in communication with the sampling pipe 12. When the sample rack 15 is pushed upward, the closing component is used to close one end of the sampling pipe 12. That is, when the sample rack 15 moves upward, the convex rod 39 at its upper end cooperates with the opening and closing groove 40. When the convex rod 39 moves to the threaded groove area of the opening and closing groove 40, at this time, the convex rod 39 exerts a force on the rotating rod 36, and the rotating rod 36 deflects 90° under the action of the force. The rotating rod 36 drives the opening and closing plate 37 to deflect 90° synchronously, so that the opening and closing plate 37 closes one end of the sampling pipe 12. At this time, under the action of the voltage-changing component, the liquid medicine in the lower pipe 10 is evenly pressed into multiple sample pipes 16 for sampling under the action of pressure. When the sampling is completed, the staff pulls the sample rack 15 downward. The force received by the sample rack 15 is greater than the force of the limit block 33 on it. At this time, the sample rack 15 moves downward, and the sample pipe 16 is separated from the interface pipe 24. After the two are separated, they are both in a sealed state, so that the purpose of sampling is completed on the premise that the medicine does not contact the outside air.

[0052] The function of the limit component is as follows: to limit and fix the sample rack 15, so that when the sample rack 15 moves upward under the thrust of the staff to a certain height (that is, when the interface tube 24 is completely inserted into the sample tube 16), the limit block 33 limits the sample rack 15 to prevent the sample rack 15 from sliding downward under the action of gravity, which affects normal sampling. At the same time, when the sampling is completed, the staff pushes the sample rack 15 downward, so that the thrust is greater than the limiting force of the limit block 33. At this time, the sample rack 15 moves downward to reset, and the staff takes out the sample tube 16 to complete the sampling (the limit component is not an essential technical feature. When sampling, when the staff pushes the sample rack 15 upward to the maximum distance and then samples, the staff can always hold the sample rack 15 by hand, and when the sampling is completed, slide the sample rack 15 downward, and the sampling operation can also be completed).

[0053] The purpose of setting the push plate 35 inside the sample tube 16 is as follows: when the sample tube 16 is filled with liquid, as the liquid continuously enters, the push plate 35 slides downward under the action of hydraulic pressure to discharge the air inside the sample tube 16, ensuring that only the liquid medicine exists inside the sample tube 16 and there will be no excessive air, which affects the liquid medicine after sampling. At the same time, the push rod 34 is set, so that when the staff needs to detect the sample, the liquid medicine needs to be taken out. At this time, the push rod 34 is pressed to pressurize the inside, so that the liquid medicine inside is discharged outward from the check valve II 22 under the action of pressure, and the liquid medicine after sampling is discharged into the detection equipment for subsequent detection is completed.

[0054] The rest of the structure is the same as that of Embodiment 1.

[0055] Embodiment 3, referring to Figures 1 - 2 , which is the third embodiment of the present invention. The difference between this embodiment and the second embodiment is that: a communication pipe 49 is fixedly installed at the upper end of the liquid preparation tank 2, and one end of the communication pipe 49 located inside the liquid preparation tank 2 is fixedly communicated with an expansion ball 50. The expansion ball 50 is located above the inside of the liquid preparation tank 2, and the inside of the expansion ball 50 is communicated with the outside air through the communication pipe 49.

[0056] Specifically, because the inside of the liquid preparation tank 2 is in a sealed state, when the staff takes a sample from its inside, the liquid medicine inside will decrease, and the pressure inside the liquid preparation tank 2 will decrease due to the decrease of the liquid medicine. In order to ensure that the pressure inside the liquid preparation tank 2 is always at a normal pressure and for normal sampling, the volume change of the expansion ball 50 communicated with the outside is used to adjust the pressure inside the liquid preparation tank 2 to ensure that the pressure inside the liquid preparation tank 2 is always in a normal state.

[0057] The rest of the structure is the same as that of Embodiment 2.

[0058] Combining Embodiments 1 - 3, the working principle of the present invention is as follows: The staff inputs the liquid medicine raw materials to be configured into the interior of the liquid preparation tank 2 through the inlet interface 6, closes the cover plate, and turns on the driving motor 4. The driving motor 4 drives the rotating shaft rod 3 to rotate through the driving end. The rotation of the rotating shaft rod 3 drives the stirring rod 5 to rotate to stir and mix the liquid medicine inside. While the rotating shaft rod 3 rotates, it drives the driven gear 42 to rotate through the driving gear 41. The rotation of the driven gear 42 continuously pulls the pull rod 48 to move through the first shaft rod 44 on the turntable 43. The pull rod 48 drives the piston plate 46 to reciprocally slide on the inner wall of the piston cylinder 45 through the second shaft rod 47. As the piston plate 46 reciprocally slides, the pressure inside the piston cylinder 45 continuously changes. When the pressure inside the piston cylinder 45 becomes smaller, the liquid medicine in the area below the liquid preparation tank 2 flows into the lower pipe 10 through the one - way pipe one under the action of pressure. When the pressure inside the piston cylinder 45 becomes larger, the liquid medicine inside the lower pipe 10 enters the upper part of the liquid preparation tank 2 through the upper pipe 9. At this time, the phenomenon of liquid medicine stratification can be prevented, and at the same time, the stirring rod 5 can better stir the liquid medicine during rotation.

[0059] When the staff needs to take a sample of the liquid medicine inside the liquid preparation tank 2, the sample tube 16 is threadedly installed on the sample rack 15, and the sample rack 15 is pushed upward. During the upward movement of the sample rack 15, the sample tube 16 moves synchronously. When the interface tube 24 is inserted into the sample tube 16, the sample tube 16 continues to move upward. At this time, the baffle 21 inside the sample tube 16 contacts the trigger rod 29 in the interface tube 24 and generates a thrust. After the trigger rod 29 receives the thrust, it slides upward. While sliding, one end of it drives the isolation plate 27 to move upward, so that a gap is generated between the isolation plate 27 and the interface tube 24. When the trigger rod 29 rises to a certain height (i.e., after the reset plate 30 is in close contact with the support plate 28), the trigger rod 29 will not continue to slide upward. At this time, during the continuous upward movement of the sample tube 16, the baffle 21 receives the reverse thrust of the trigger rod 29. At this time, the baffle 21 moves downward inside the conical sleeve 20, and a gap is generated between the baffle 21 and the conical sleeve 20. At this time, the sampling tube 12 is communicated with the sample tube 16. While the sample rack 15 is pushed upward, the convex rod 39 at its upper end slides in the opening - closing groove 40. When it slides to the threaded groove area, the convex rod 39 drives the rotating rod 36 to rotate 90°. At this time, the opening - closing plate 37 at the upper end of the rotating rod 36 rotates 90° synchronously, so that the opening - closing plate 37 closes one end of the sampling tube 12, making the sampling tube 12 only communicate with the sample tube 16 at this time. At the same time, the sample rack 15 just moves above the limit block 33. At this time, the limit block 33 limits the sample rack 15 to prevent it from sliding downward. When the sampling is completed, the staff presses the sample rack 15 downward, so that the sample tube 16 on the sample rack 15 slides downward synchronously and disengages from the interface tube 24. At this time, both the sample tube 16 and the interface tube 24 are in a closed state.

[0060] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than to limit them. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be modified or equivalently replaced without departing from the spirit and scope of the technical solutions of the present invention, and they should all be covered within the scope of the claims of the present invention.

Claims

1. A sampling device for detecting liquid medicine in a liquid preparation tank in a biological laboratory, comprising a plurality of support rods, a liquid preparation tank disposed between the plurality of support rods, a rotating shaft rod that is sealed and rotated and penetrates the bottom end of the liquid preparation tank, a driving motor disposed at the lower end of the rotating shaft rod, a plurality of stirring rods disposed on the outer wall of the rotating shaft rod, an inlet interface and an outlet interface disposed at the upper end of the liquid preparation tank, characterized in that: It also includes a sampling unit arranged on the liquid preparation tank, the sampling unit includes a sampling component arranged on the side wall of the liquid preparation tank and a pressure changing component arranged on the outer wall of the lower end of the liquid preparation tank; The sampling component includes a sampling sleeve arranged on the outer wall of the liquid dispensing tank, an upper tube arranged on the upper end of the sampling sleeve, a lower tube arranged on the sampling sleeve, a return pipe arranged on the side wall of the upper tube, a sampling tube arranged on the side wall of the lower tube, a connecting pipe arranged between the return pipe and the sampling tube, a slide rail arranged on the two side walls of the sampling sleeve, a sample rack slidably arranged between the two slide rails, a plurality of mounting holes provided on the sample rack, and sample tubes threadedly arranged on the plurality of mounting holes, a one-way valve with opposite flow directions is installed inside the upper tube and the lower tube, a one-way component is installed inside the plurality of sample tubes, and a plurality of matching components matching with the one-way components are installed on the lower wall of the sampling tube; The one-way component includes a mounting ring 1 arranged at the tube mouth at the upper end inside the sample tube, a middle rod arranged on the mounting ring 1, a spring rod arranged on the middle rod, a conical sleeve arranged at the upper end of the mounting ring 1, a baffle arranged at the upper end of the spring rod, and a plurality of one-way valves 2 arranged on the baffle, the end face size of the baffle is equal to the end face size of the upper end of the conical sleeve, the baffle is located inside the upper end of the conical sleeve, and a limit ring for limiting the baffle in the upward direction is fixedly installed on the upper end of the conical sleeve.

2. A sampling device for detecting liquid medicine in a liquid preparation tank in a biological laboratory according to claim 1, characterized in that: The driving end of the driving motor is fixedly connected to the lower end of the rotating shaft rod, the upper end of the upper tube is fixedly connected to the internal upper end of the liquid dispensing tank, the lower end of the lower tube is fixedly connected to the internal lower end of the liquid dispensing tank, the reflux pipe and the sampling tube are both located inside the sampling sleeve, a closing component is installed between the sampling tube and the sample rack, and limiting components are installed inside the two slide rails.

3. A sampling device for detecting liquid medicine in a liquid preparation tank in a biological laboratory according to claim 2, characterized in that: The matching assembly includes a plurality of interface tubes arranged at the lower end of the sampling tube, a mounting ring 2 arranged on the inner wall of the interface tube, a telescopic spring arranged on the mounting ring 2, an isolation plate arranged on the upper end of the telescopic spring, a support plate arranged on the inner wall of the interface tube, a trigger rod arranged on the support plate that is sealed and slidable through, a reset plate arranged on the trigger rod, and a reset spring arranged between the reset plate and the support plate.

4. A sampling device for detecting liquid medicine in a liquid preparation tank in a biological laboratory according to claim 2, characterized in that: The limiting assembly comprises mounting grooves provided on two slide rails, limiting springs respectively arranged on the inner walls of the two mounting grooves, and a limiting block arranged at one end of the limiting spring, wherein the limiting block slides in the mounting grooves.

5. A sampling device for detecting liquid medicine in a liquid preparation tank in a biological laboratory according to claim 3, characterized in that: The lower ends of the plurality of sample tubes are all sealed and slidably provided with push rods, the upper end of each push rod is fixedly provided with a push plate, the shape and size of the end face of each push plate are the same as the shape and size of the end face of the inner wall of the sample tube, and a sealing ring is fixedly sleeved on the side wall of each push plate.

6. A sampling device for detecting liquid medicine in a liquid preparation tank in a biological laboratory according to claim 2, characterized in that: The closing component includes a rotating rod rotatably mounted on the sampling tube, an opening and closing plate arranged on the rotating rod, a block arranged on the sample rack, a convex rod arranged on the block, and an opening and closing groove formed on the rotating rod, wherein the opening and closing groove consists of a vertical groove and a spiral groove, the lower end of the rotating rod slides through the sample rack, one end of the convex rod is located inside the opening and closing groove, the opening and closing plate is located inside the sampling tube, and the end face size of the opening and closing plate is the same as the end face size of the inner wall of the sampling tube.

7. A sampling device for detecting liquid medicine in a liquid preparation tank in a biological laboratory according to claim 1, characterized in that: The voltage-changing component comprises a driving gear arranged on the outer wall of the rotating shaft rod, a driven gear arranged on the lower end of the liquid dispensing tank, a turntable arranged on the lower end of the driven gear, a shaft rod 1 arranged on the turntable, a piston cylinder arranged on the lower end of the liquid dispensing tank, a piston plate sealingly and slidably arranged on the inner wall of the piston cylinder, a square groove provided on the piston plate, a shaft rod 2 arranged in the square groove, a pull rod rotatably arranged on the shaft rod 2, one end of the pull rod away from the shaft rod 2 is rotatably connected to the shaft rod 1, the end face shape and size of the piston plate are the same as the end face shape and size of the inner wall of the piston cylinder, and one end of the piston cylinder (45) is fixedly connected to the side wall of the lower tube (10) through a short tube.

8. A sampling device for detecting liquid medicine in a liquid preparation tank in a biological laboratory according to claim 7, characterized in that: A connecting pipe is fixedly installed on the upper end of the liquid dispensing tank, and an expansion ball is fixedly connected to one end of the connecting pipe located inside the liquid dispensing tank. The expansion ball is located above the inside of the liquid dispensing tank, and the inside of the expansion ball is connected to the outside air through the connecting pipe.

9. A sampling device for detecting liquid medicine in a liquid preparation tank in a biological laboratory according to claim 5, characterized in that: The size of the outer wall of the interface tube is equal to the size of the inner wall of the sample tube.

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