A veterinary drug testing sample preparation device

Abstract

The present invention relates to the technical field of preparation devices, and discloses a veterinary drug test sample preparation device, including two support plates, two extrusion cylinders are rotatably installed between the two support plates, the circumferential outer surfaces of the two extrusion cylinders are against each other, and a shell is fixedly installed between the two support plates. The present invention uses two extrusion cylinders to extrude muscle tissue that falls on the surface thereof, so that the extruded muscle tissue enters the interior of the extrusion hole, and two stirring fans drive the spiral blades to move relative to the inner wall of the extrusion cylinder, so that the spiral blades shear the muscle tissue coming in from the interior of the extrusion hole, and the sheared muscle tissue is mixed in an acetonitrile extraction solvent. The device can quickly shear and break up the muscle tissue samples of the animal, so that it is fully mixed with the acetonitrile extraction solvent, ensuring that all the residues of the veterinary drug can enter the acetonitrile extraction solvent, and ensuring the accuracy of subsequent detection.

Description

Technical Field

[0001] The invention relates to the technical field of preparation devices, and in particular to a veterinary drug detection sample preparation device. Background Art

[0002] Veterinary drugs are substances used to prevent, treat, diagnose animal diseases or purposefully regulate animal physiological functions, mainly including serum products, vaccines, diagnostic products, microecological products, Chinese herbal medicines, chemicals, antibiotics, biochemical drugs, radioactive drugs, external pesticides, disinfectants, etc. As people's demand for animal-derived foods shifts from demand-oriented to quality-oriented, veterinary drug residues in animal-derived foods have gradually become a focus of worldwide attention. Veterinary drug residues refer to the prototype drug or its metabolites that accumulate or remain in the body of livestock and poultry or products after use, including impurity residues related to veterinary drugs.

[0003] When the existing veterinary drug detection sample preparation device is used, the muscle tissue of the animal is directly crushed by a crusher, and then mixed with an acetonitrile extraction solvent to dissolve the drug residue inside the muscle into the acetonitrile extraction solvent, and then the mixed extraction solvent is concentrated and extracted by an extraction device. Since the existing device does not fully crush the muscle tissue during crushing, some drugs remain inside the muscle tissue when the extraction solvent is subsequently extracted, affecting the accuracy of subsequent detection. Summary of the invention

[0004] The purpose of the present invention is to solve the shortcomings of the prior art and to propose a veterinary drug detection sample preparation device.

[0005] In order to achieve the above object, the present invention adopts the following technical solutions:

[0006] A veterinary drug detection sample preparation device comprises two support plates, two extrusion cylinders are rotatably mounted between the two support plates, the circumferential outer surfaces of the two extrusion cylinders are against each other, a shell is fixedly mounted between the two support plates, the two extrusion cylinders are arranged inside the shell, a feed hopper is fixedly mounted on the upper surface of the shell, the feed hopper is connected with the inside of the shell, a plurality of extrusion holes are penetrated through the circumferential outer surfaces of the two extrusion cylinders, the extrusion holes on the adjacent circumferential outer surfaces of the two extrusion cylinders are arranged alternately, the two ends of the two extrusion cylinders respectively penetrate the outer surfaces of the two support plates, a first sealing plate is fixedly mounted on the outer surface of one side of one of the support plates, the outer surface of the first sealing plate is fitted with the end surfaces of the two extrusion cylinders, two stirring fans are rotatably mounted on the outer surface of one side of the first sealing plate, the two stirring fans are respectively arranged inside the two extrusion cylinders, a plurality of spiral blades are equidistantly arranged on the circumferential outer surfaces of the stirring fans, the outer surfaces of the plurality of spiral blades are against the inner wall of the extrusion cylinder, and the outer surfaces of the spiral blades are against the inner wall of the extrusion cylinder, so that the two can shear muscle tissue when they move relative to each other.

[0007] As a further solution of the present invention, an annular gear is fixedly installed on the outer surface of the support plate at one end of the two extrusion cylinders close to the first sealing plate, and two gears are symmetrically installed on the outer surface of the support plate close to the annular gear for rotation. The two gears are meshed with each other, and the two gears are respectively meshed with adjacent annular gears.

[0008] As a further solution of the present invention, a rotating shaft is fixedly installed on the outer surfaces of the two gear rotation centers, the rotating shaft passes through the outer surface of the first sealing plate and is fixedly installed with a second synchronous pulley, the two stirring fans pass through the outer surface of the first sealing plate at one end close to the second synchronous pulley and are fixedly installed with the first synchronous pulley, and the outer surfaces of the first synchronous pulley and the second synchronous pulley are sleeved with synchronous belts.

[0009] As a further solution of the present invention, a second sealing plate is fixedly installed on the outer surface of one side of the other support plate, the second sealing plate is flush with the other end of the two extrusion cylinders, and a driving motor is fixedly installed on the outer surface of one side of the second sealing plate. The output end of the driving motor passes through the outer surface of the second sealing plate and is fixedly installed on the rotation center of one of the stirring fans.

[0010] As a further solution of the present invention, two blowing hoods are fixedly installed between the two support plates, and openings are provided at the bottom ends of the two blowing hoods. The bottom ends of the two blowing hoods are respectively flush with the circumferential outer surfaces of the two extrusion cylinders, and the air inlet ends of the two blowing hoods pass through the outer surface of the second sealing plate and are fixedly installed with an air pipe, and the two blowing hoods are connected through the air pipe, and a piston cylinder is fixedly installed on the outer surface of one side of the second sealing plate, and the air outlet end of the piston cylinder is connected to the air pipe through a hose.

[0011] As a further solution of the present invention, a piston plate is slidably installed on the inner wall of the piston cylinder, and a one-way air nozzle is fixedly installed on the outer surface of the piston plate, and the one-way air nozzle is connected to the interior of the piston cylinder; another end of the stirring fan close to the driving motor passes through the outer surface of the support plate and a turntable is fixedly installed; a driving column is fixedly installed on the outer surface of one side of the turntable, and the driving column is arranged at an eccentric position of the turntable; a connecting rod is rotatably installed on the outer surface of the driving column, and the other end of the connecting rod is rotatably installed on the outer surface of the center position of the piston plate.

[0012] As a further solution of the present invention, two eccentric shafts are symmetrically rotatably installed between the two support plates, and the outer surfaces of the two eccentric shafts are sleeved with moving plates. Two waist-shaped holes are symmetrically provided inside the moving plates, and the two eccentric shafts are respectively slidably installed on the inner walls of the two waist-shaped holes. Limiting blocks are fixedly installed on the outer surfaces of the opposite ends of the moving plates, and limiting grooves are provided on the outer surfaces of the support plates close to the limiting blocks. The limiting blocks are slidably installed on the inner walls of the limiting grooves. The moving plates are arranged above the two extrusion cylinders and a gap is provided between the moving plates and the two extrusion cylinders. The cross-section of the moving plates is rhombus-shaped, and the adjacent ends of the two eccentric shafts pass through the outer surfaces of the support plates and are respectively fixedly installed on the rotation centers of the two gears.

[0013] As a further scheme of the present invention, a through hole is provided on the lower surface of the shell, and the inner wall of the through hole is threadedly connected with a discharging cylinder, and the inner wall of the discharging cylinder near the bottom end is fixedly installed with a conical plate, and the outer surface of the middle position of the conical plate passes through a liquid outlet hole, and the top of the discharging cylinder is slidably inserted with a sliding column, and the top of the sliding column is fixedly installed with a floating plate, and the bottom end of the sliding column passes through the top wall of the discharging cylinder and is fixedly installed with a plug, the outer surface of the plug is against the inner wall of the liquid outlet hole, and the circumferential outer surface of the discharging cylinder passes through a plurality of liquid inlet holes, and the liquid inlet hole is arranged inside the shell, and a spring plunger is fixedly installed on the inner wall of the discharging cylinder, and a steel ball is slidably installed on the inner wall of the spring plunger near the top end, and the steel ball is against the outer surface of the sliding column, and a spring is arranged inside the spring plunger, and the spring is arranged between the steel ball and the spring plunger, and a groove is provided on the circumferential outer surface of the sliding column, and the steel ball is matched with the inner wall of the groove.

[0014] Compared with the prior art, the present invention has the following beneficial effects:

[0015] 1. The muscle tissue falling on the surface is squeezed by two squeezing cylinders, so that the squeezed muscle tissue will enter the inside of the squeezing hole. The two stirring fans drive the spiral blades and the inner wall of the squeezing cylinder to move relative to each other, so that the spiral blades shear the muscle tissue coming in from the squeezing hole. The sheared muscle tissue is mixed in the acetonitrile extraction solvent. The muscle tissue samples of animals can be quickly sheared and broken by this device, so that they are fully mixed with the acetonitrile extraction solvent, ensuring that the residues of veterinary drugs can all enter the acetonitrile extraction solvent, and ensuring the accuracy of subsequent detection;

[0016] 2. The driving column drives the piston plate to reciprocate through the connecting rod, so that the piston plate compresses the piston cylinder. During compression, the air inside the piston cylinder enters the inside of the two blowing hoods through the hose and the air pipe, and the gas is blown out from the extrusion holes of the extrusion cylinder through the blowing hood. The movement frequency of the piston plate is relatively fast, ensuring that all the extrusion holes can be blown. Through this device, the muscle tissue inside the extrusion holes can be blown out to avoid the blockage of the extrusion holes affecting the subsequent shearing and crushing of the muscle tissue;

[0017] 3. The slide column is driven upward by the floating plate, and the steel ball is inserted into the inside of the groove through the spring. At this time, the position of the slide column is fixed, and the plug is driven away from the liquid outlet by the floating plate, and the liquid outlet is opened. At this time, the mixed acetonitrile extraction solvent liquid in the shell flows into the collection box below through the liquid inlet and outlet holes. This device ensures that the acetonitrile extraction solvent and muscle tissue fragments are fully mixed before collecting the mixed solution, ensuring that the substances inside the muscle tissue are fully mixed in the acetonitrile extraction solvent liquid, and further ensuring that the veterinary drug residues can be completely dissolved in the acetonitrile extraction solvent, making the subsequent detection data more accurate. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic diagram of the overall structure of a veterinary drug detection sample preparation device proposed by the present invention;

[0019] Figure 2 This is a front structural schematic diagram of a veterinary drug detection sample preparation device proposed by the present invention;

[0020] Figure 3 This is a schematic diagram of the structure of a veterinary drug detection sample preparation device proposed by the present invention from a bottom-up perspective;

[0021] Figure 4 This is a schematic diagram of the internal structure of a veterinary drug detection sample preparation device proposed by the present invention;

[0022] Figure 5 A schematic diagram of a stirring fan of a veterinary drug test sample preparation device proposed by the present invention;

[0023] Figure 6 A schematic diagram of an extrusion cylinder of a veterinary drug test sample preparation device proposed by the present invention;

[0024] Figure 7 A schematic diagram of a blowing hood of a veterinary drug test sample preparation device proposed by the present invention;

[0025] Figure 8 A schematic diagram of a floating plate of a veterinary drug test sample preparation device proposed by the present invention;

[0026] Fig. 9 A schematic diagram of a motion plate of a veterinary drug testing sample preparation device proposed by the present invention;

[0027] Fig.10 A schematic diagram of an eccentric shaft of a veterinary drug test sample preparation device proposed by the present invention;

[0028] Fig.11 This is a schematic diagram of a spring plunger in a veterinary drug testing sample preparation device proposed by the present invention.

[0029] In the figure: 1. support plate; 2. shell; 3. feed hopper; 4. drive motor; 5. first sealing plate; 6. second sealing plate; 7. piston cylinder; 8. turntable; 9. connecting rod; 10. drive column; 11. air pipe; 12. one-way air nozzle; 13. first synchronous pulley; 14. synchronous belt; 15. second synchronous pulley; 16. ring gear; 17. gear; 18. discharge barrel; 19. liquid inlet hole; 20. liquid outlet hole; 21. floating plate; 22. plug; 23. groove; 24. spring plunger; 25. stirring fan; 26. extrusion barrel; 27. blowing hood; 28. eccentric shaft; 29. ​​moving plate; 30. piston plate; 31. steel ball; 32. spring; 33. waist-shaped hole; 34. limit block. DETAILED DESCRIPTION

[0030] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further explained below in conjunction with specific implementation methods.

[0031] In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "two ends", "one end", "the other end" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0032] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "provided with", "connected", etc. should be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0033] Reference Figure 1-Figure 11 A veterinary drug test sample preparation device comprises two support plates 1, two extrusion cylinders 26 are rotatably installed between the two support plates 1, the circumferential outer surfaces of the two extrusion cylinders 26 are against each other, a shell 2 is fixedly installed between the two support plates 1, the two extrusion cylinders 26 are arranged inside the shell 2, a feed hopper 3 is fixedly installed on the upper surface of the shell 2, the feed hopper 3 is connected with the inside of the shell 2, a plurality of extrusion holes are penetrated through the circumferential outer surfaces of the two extrusion cylinders 26, the extrusion holes on the adjacent circumferential outer surfaces of the two extrusion cylinders 26 are staggered, the two ends of the two extrusion cylinders 26 respectively penetrate the outer surfaces of the two support plates 1, and a first sealing plate 5 is fixedly installed on the outer surface of one side of one of the support plates 1 The outer surface of the first sealing plate 5 fits with the end surfaces of the two extrusion cylinders 26. Two stirring fans 25 are rotatably installed on the outer surface of one side of the first sealing plate 5. The two stirring fans 25 are respectively arranged inside the two extrusion cylinders 26. A plurality of spiral blades are equidistantly arranged on the circumferential outer surface of the stirring fan 25. The outer surfaces of the plurality of spiral blades abut against the inner walls of the extrusion cylinders 26. The outer surfaces of the spiral blades abut against the inner walls of the extrusion cylinders 26, so that the muscle tissue can be sheared when the two move relative to each other. The surface of the extrusion cylinder 26 is relatively rough, ensuring that the muscle tissue of the animal will not slip on the upper surface. The extrusion holes are staggered to ensure that all the muscle tissue of the animal can be squeezed.

[0034] The muscle tissue falling on the surface is squeezed by two squeezing cylinders 26, so that the squeezed muscle tissue enters the inside of the squeezing hole, and the two stirring fans 25 drive the spiral blades and the inner wall of the squeezing cylinder 26 to move relative to each other, so that the spiral blades shear the muscle tissue coming in from the inside of the squeezing hole, and the sheared muscle tissue is mixed in the acetonitrile extraction solvent. The device can quickly shear and break up the muscle tissue samples of the animal so that they are fully mixed with the acetonitrile extraction solvent, ensuring that the residues of the veterinary drugs can all enter the acetonitrile extraction solvent, thereby ensuring the accuracy of subsequent detection.

[0035] In this embodiment, one end of the two extrusion cylinders 26 close to the first sealing plate 5 passes through the outer surface of the support plate 1 and is fixedly installed with an annular gear 16. Two gears 17 are symmetrically installed on the outer surface of the support plate 1 close to the annular gear 16. The two gears 17 are meshed with each other, and the two gears 17 are respectively meshed with adjacent annular gears 16. The outer surfaces of the rotation centers of the two gears 17 are fixedly installed with a rotating shaft, and the rotating shaft passes through the outer surface of the first sealing plate 5 and is fixedly installed with a second synchronous pulley 15. One end of the two stirring fans 25 close to the second synchronous pulley 15 passes through the outer surface of the first sealing plate 5 and is fixedly installed with a first synchronous pulley 13. The outer surfaces of the first synchronous pulley 13 and the second synchronous pulley 15 are sleeved with a synchronous belt 14. The outer surface of one side of the other support plate 1 is fixedly installed with a second sealing plate 6. The second sealing plate 6 is flush with the other ends of the two extrusion cylinders 26. The outer surface of one side of the second sealing plate 6 is fixedly installed with a driving motor 4. The output end of the driving motor 4 passes through the outer surface of the second sealing plate 6 and is fixedly installed with the rotation center of one of the stirring fans 25.

[0036] The driving motor 4 drives one of the stirring fans 25 to rotate, so that the stirring fan 25 drives the first synchronous pulley 13 to rotate, the first synchronous pulley 13 drives the second synchronous pulley 15 to rotate through the synchronous belt 14, and the second synchronous pulley 15 drives the gear 17 to rotate, so that the gear 17 drives another gear 17 to rotate in the opposite direction, and the two gears 17 drive the two extrusion cylinders 26 to rotate in the opposite direction through the two annular gears 16, so that the two extrusion cylinders 26 squeeze the muscle tissue falling on the surface thereof, and the muscle tissue will enter the inside of the extrusion hole through the squeezing, and the second synchronous pulley 1 is driven by another gear 17. 5 rotates, the second synchronous pulley 15 drives another first synchronous pulley 13 to rotate through the synchronous belt 14, and the other first synchronous pulley 13 drives another stirring fan 25 to rotate. The two stirring fans 25 drive the spiral blades and the inner wall of the extrusion cylinder 26 to move relative to each other, so that the spiral blades shear the muscle tissue coming from the inside of the extrusion hole, and the sheared muscle tissue is mixed in the acetonitrile extraction solvent. With the rotation of the extrusion cylinder 26 and the stirring fan 25, the mixture is continuously sheared and crushed. Through this device, the muscle tissue sample of the animal can be quickly sheared and crushed, so that it can be fully mixed with the acetonitrile extraction solvent.

[0037] In this embodiment, two blowing hoods 27 are fixedly installed between the two support plates 1, and the bottom ends of the two blowing hoods 27 are provided with openings. The bottom ends of the two blowing hoods 27 are respectively flush with the circumferential outer surfaces of the two extrusion cylinders 26, and the air inlet ends of the two blowing hoods 27 penetrate the outer surface of the second sealing plate 6 and are fixedly installed with an air pipe 11. The two blowing hoods 27 are connected through the air pipe 11. The outer surface of one side of the second sealing plate 6 is fixedly installed with a piston cylinder 7. The air outlet end of the piston cylinder 7 is connected to the air pipe 11 through a hose. A piston plate 30 is slidably installed on the inner wall, and a one-way air nozzle 12 is fixedly installed on the outer surface of the piston plate 30, and the one-way air nozzle 12 is connected to the interior of the piston cylinder 7. Another stirring fan 25, one end close to the driving motor 4, passes through the outer surface of the support plate 1 and is fixedly installed with a turntable 8. A driving column 10 is fixedly installed on the outer surface of one side of the turntable 8, and the driving column 10 is arranged at an eccentric position of the turntable 8. A connecting rod 9 is rotatably installed on the outer surface of the driving column 10, and the other end of the connecting rod 9 is rotatably installed on the outer surface of the center position of the piston plate 30.

[0038] Another stirring fan 25 drives the turntable 8 to rotate, so that the turntable 8 drives the driving column 10 to move eccentrically. The driving column 10 drives the piston plate 30 to reciprocate through the connecting rod 9, so that the piston plate 30 compresses the piston cylinder 7. Through the one-way air nozzle 12, air enters the interior of the piston cylinder 7 when the piston plate 30 returns. During compression, the air inside the piston cylinder 7 enters the interior of the two blowing hoods 27 through the hose and the air pipe 11, and the gas is blown out from the extrusion holes of the extrusion cylinder 26 through the blowing hood 27. The movement frequency of the piston plate 30 is relatively fast, ensuring that all extrusion holes can be blown. Through this device, the muscle tissue inside the extrusion hole can be blown out to avoid clogging of the extrusion hole affecting the subsequent shearing and crushing of the muscle tissue.

[0039] In this embodiment, two eccentric shafts 28 are symmetrically rotatably installed between the two support plates 1, and a moving plate 29 is sleeved on the outer surfaces of the two eccentric shafts 28. Two waist-shaped holes 33 are symmetrically provided inside the moving plate 29. The two eccentric shafts 28 are respectively slidably installed with the inner walls of the two waist-shaped holes 33. Limiting blocks 34 are fixedly installed on the outer surfaces of the opposite ends of the moving plate 29. A limiting groove is provided on the outer surface of the support plate 1 close to the limiting block 34. The limiting block 34 is slidably installed with the inner wall of the limiting groove. The moving plate 29 is arranged above the two extrusion cylinders 26 and a gap is provided between the two extrusion cylinders 26. The cross-section of the moving plate 29 is a diamond-shaped arrangement. The adjacent ends of the two eccentric shafts 28 penetrate the outer surface of the support plate 1 and are respectively fixedly installed with the rotation center of the two gears 17. The two eccentric shafts 28 are driven to move eccentrically through the two gears 17. The eccentric shaft 28 drives the moving plate 29 to move up and down along the limiting groove through the waist-shaped hole 33, so that the moving plate 29 presses the muscle tissue downward through the outer shape, so that the muscle tissue is conveniently squeezed by the extrusion cylinder 26.

[0040] In this embodiment, a through hole is provided on the lower surface of the shell 2, and a discharge barrel 18 is threadedly connected to the inner wall of the through hole. A conical plate is fixedly installed on the inner wall of the discharge barrel 18 near the bottom end, and a liquid outlet hole 20 is penetrated through the outer surface of the middle position of the conical plate. A sliding column is slidably inserted at the top of the discharge barrel 18, and a floating plate 21 is fixedly installed on the top of the sliding column. A plug 22 is fixedly installed on the top wall of the discharge barrel 18 at the bottom end of the sliding column, and the outer surface of the plug 22 is against the inner wall of the liquid outlet hole 20. The circular surface of the discharge barrel 18 A plurality of liquid inlet holes 19 are formed through the outer surface of the circumference, and the liquid inlet holes 19 are arranged inside the shell 2. A spring plunger 24 is fixedly installed on the inner wall of the discharge barrel 18, and a steel ball 31 is slidably installed on the inner wall of the spring plunger 24 near the top, and the steel ball 31 is abutted against the outer surface of the sliding column. A spring 32 is arranged inside the spring plunger 24, and the spring 32 is arranged between the steel ball 31 and the spring plunger 24. A groove 23 is formed on the outer surface of the circumference of the sliding column, and the steel ball 31 is matched with the inner wall of the groove 23.

[0041] The slide column is driven upward by the float plate 21, and the steel ball 31 is inserted into the inside of the groove 23 by the spring 32. At this time, the position of the slide column is fixed, and the plug 22 is driven to leave the liquid outlet 20 by the floating of the float plate 21, and the liquid outlet 20 is opened. At this time, the mixed acetonitrile extraction solvent liquid in the shell 2 flows into the collection box below through the liquid inlet hole 19 and the liquid outlet hole 20. After all the liquid is collected, it is transferred to the next extraction process. The device ensures that the acetonitrile extraction solvent and the muscle tissue fragments are fully mixed before collecting the mixed solution, which ensures that the substances inside the muscle tissue are fully mixed in the acetonitrile extraction solvent liquid, further ensuring that the veterinary drug residues can be completely dissolved in the acetonitrile extraction solvent, so that the subsequent detection data is more accurate.

[0042] In this embodiment, the upward and downward movement of the moving plate 29 is limited by the limiting block 34 and the limiting groove.

[0043] It should be noted that when the present invention is used, the user adds a certain amount of animal muscle tissue into the interior of the housing 2 through the feed hopper 3, and then injects a certain amount of acetonitrile extraction solvent into the interior of the housing 2, and drives one of the stirring fans 25 to rotate through the driving motor 4, so that the stirring fan 25 drives the first synchronous pulley 13 to rotate, and the first synchronous pulley 13 drives the second synchronous pulley 15 to rotate through the synchronous belt 14, and the second synchronous pulley 15 drives the gear 17 to rotate, so that the gear 17 drives another gear 17 to rotate in the opposite direction, and the two gears 17 drive the two extrusion cylinders 26 to rotate in the opposite direction through the two annular gears 16, so that the two extrusion cylinders 26 are opposite to each other. The muscle tissue falling on the surface is squeezed, and the muscle tissue enters the inside of the extrusion hole through squeezing, and the second synchronous pulley 15 is driven to rotate by another gear 17, and the second synchronous pulley 15 drives another first synchronous pulley 13 to rotate through the synchronous belt 14, and another first synchronous pulley 13 drives another stirring fan 25 to rotate, and the two stirring fans 25 drive the spiral blades and the inner wall of the extrusion cylinder 26 to move relative to each other, so that the spiral blades shear the muscle tissue coming in from the extrusion hole, and the sheared muscle tissue is mixed in the acetonitrile extraction solvent. With the rotation of the extrusion cylinder 26 and the stirring fan 25, the mixture is continuously sheared and crushed. The device can quickly shear and shred the muscle tissue samples of animals, so that they are fully mixed with the acetonitrile extraction solvent, ensuring that the residues of veterinary drugs can all enter the acetonitrile extraction solvent, ensuring the accuracy of subsequent detection; at the same time, the two eccentric shafts 28 are driven to move eccentrically through the two gears 17, and the eccentric shafts 28 drive the moving plate 29 to move up and down along the limit groove through the waist-shaped hole 33, so that the moving plate 29 presses the muscle tissue downward through the shape, so that the muscle tissue is convenient for being squeezed by the extrusion cylinder 26; another stirring fan 25 drives the turntable 8 to rotate, so that the turntable 8 drives the driving column 10 to move eccentrically, and the driving column 10 drives the piston plate 30 to reciprocate through the connecting rod 9, so that The piston plate 30 compresses the piston cylinder 7, and air enters the interior of the piston cylinder 7 through the one-way air nozzle 12 during the return stroke of the piston plate 30. During compression, the air inside the piston cylinder 7 enters the interior of the two blowing hoods 27 through the hose and the air pipe 11, and the gas is blown out from the extrusion holes of the extrusion cylinder 26 through the blowing hood 27. The movement frequency of the piston plate 30 is relatively fast, ensuring that all extrusion holes can be blown. Through this device, the muscle tissue inside the extrusion hole can be blown out to avoid the blockage of the extrusion hole affecting the subsequent shearing and crushing of the muscle tissue; when the substance inside the muscle tissue is fully mixed with the acetonitrile extraction solvent, since the density of the acetonitrile extraction solvent is about 0.79g / cm 3 , while the density of muscle tissue is about 1.06g / cm 3 When the two are fully mixed, the density of the mixed liquid will be greater than 0.79g / cm 3, so that the float plate 21 floats up, and the slide column is driven to move upward by the float plate 21, and the steel ball 31 is inserted into the inside of the groove 23 by the spring 32. At this time, the position of the slide column is fixed, and the plug 22 is driven to leave the liquid outlet 20 by the floating of the float plate 21, and the liquid outlet 20 is opened. At this time, the mixed acetonitrile extraction solvent liquid in the shell 2 flows into the collection box below through the liquid inlet hole 19 and the liquid outlet hole 20. After all the liquids are collected, it is transferred to the next extraction process. The device ensures that the acetonitrile extraction solvent and the muscle tissue fragments are fully mixed before collecting the mixed solution, which ensures that the substances inside the muscle tissue are fully mixed in the acetonitrile extraction solvent liquid, further ensuring that the veterinary drug residues can be completely dissolved in the acetonitrile extraction solvent, so that the subsequent detection data is more accurate.

[0044] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A veterinary drug test sample preparation device, comprising two support plates (1), characterized in that: Two extrusion cylinders (26) are rotatably mounted between the two support plates (1), the circumferential outer surfaces of the two extrusion cylinders (26) are against each other, a shell (2) is fixedly mounted between the two support plates (1), the two extrusion cylinders (26) are arranged inside the shell (2), a feed hopper (3) is fixedly mounted on the upper surface of the shell (2), the feed hopper (3) is connected to the inside of the shell (2), a plurality of extrusion holes are penetrated through the circumferential outer surfaces of the two extrusion cylinders (26), the extrusion holes on the adjacent circumferential outer surfaces of the two extrusion cylinders (26) are arranged in an interlaced manner, and both ends of the two extrusion cylinders (26) are provided with a plurality of extrusion holes. The first sealing plate (5) is fixedly mounted on the outer surface of one side of the support plates (1), and the outer surface of the first sealing plate (5) is in contact with the end surfaces of the two extrusion cylinders (26). Two stirring fans (25) are rotatably mounted on the outer surface of one side of the first sealing plate (5). The two stirring fans (25) are respectively arranged inside the two extrusion cylinders (26). A plurality of spiral blades are equidistantly arranged on the circumferential outer surface of the stirring fan (25). The outer surfaces of the plurality of spiral blades are in contact with the inner wall of the extrusion cylinder (26). The two extrusion cylinders (26) are close to the first sealing plate. One end of the sealing plate (5) passes through the outer surface of the support plate (1) and is fixedly mounted with a circular gear (16); two gears (17) are symmetrically mounted on the outer surface of the support plate (1) near the circular gear (16); the two gears (17) are meshed with each other; the two gears (17) are respectively meshed with adjacent circular gears (16); two eccentric shafts (28) are symmetrically mounted between the two support plates (1); a moving plate (29) is sleeved on the outer surface of the two eccentric shafts (28); two waist-shaped holes (33) are symmetrically provided inside the moving plate (29); the two eccentric shafts (28) are The movable plate (29) is slidably mounted on the inner walls of the two waist-shaped holes (33) respectively. The outer surfaces of the two opposite ends of the movable plate (29) are fixedly mounted with limit blocks (34). The outer surface of the support plate (1) close to the limit blocks (34) is provided with limit grooves. The limit blocks (34) are slidably mounted on the inner walls of the limit grooves. The movable plate (29) is arranged above the two extrusion cylinders (26) and a gap is provided between the movable plate (29) and the two extrusion cylinders (26). The cross section of the movable plate (29) is rhombus-shaped. The adjacent ends of the two eccentric shafts (28) penetrate the outer surface of the support plate (1) and are fixedly mounted on the rotation centers of the two gears (17) respectively.

2. A veterinary drug detection sample preparation device according to claim 1, characterized in that: The outer surfaces of the rotation centers of the two gears (17) are fixedly mounted with a rotating shaft, the rotating shaft passes through the outer surface of the first sealing plate (5) and is fixedly mounted with a second synchronous pulley (15), one end of the two stirring fans (25) close to the second synchronous pulley (15) passes through the outer surface of the first sealing plate (5) and is fixedly mounted with a first synchronous pulley (13), and the outer surfaces of the first synchronous pulley (13) and the second synchronous pulley (15) are sleeved with a synchronous belt (14).

3. A veterinary drug detection sample preparation device according to claim 2, characterized in that: A second sealing plate (6) is fixedly mounted on the outer surface of one side of the other support plate (1), the second sealing plate (6) is flush with the other ends of the two extrusion cylinders (26), a driving motor (4) is fixedly mounted on the outer surface of one side of the second sealing plate (6), and the output end of the driving motor (4) passes through the outer surface of the second sealing plate (6) and is fixedly mounted at the rotation center of one of the stirring fans (25).

4. A veterinary drug detection sample preparation device according to claim 3, characterized in that: Two blowing hoods (27) are fixedly installed between the two support plates (1), the bottom ends of the two blowing hoods (27) are provided with openings, the bottom ends of the two blowing hoods (27) are respectively flush with the circumferential outer surfaces of the two extrusion cylinders (26), the air inlet ends of the two blowing hoods (27) penetrate the outer surface of the second sealing plate (6) and are fixedly installed with an air pipe (11), the two blowing hoods (27) are connected through the air pipe (11), the outer surface of one side of the second sealing plate (6) is fixedly installed with a piston cylinder (7), and the air outlet end of the piston cylinder (7) is connected with the air pipe (11) through a hose.

5. A veterinary drug detection sample preparation device according to claim 4, characterized in that: A piston plate (30) is slidably mounted on the inner wall of the piston cylinder (7), and a one-way air nozzle (12) is fixedly mounted on the outer surface of the piston plate (30). The one-way air nozzle (12) is connected to the interior of the piston cylinder (7). One end of the other stirring fan (25) close to the driving motor (4) passes through the outer surface of the support plate (1) and is fixedly mounted with a turntable (8). A driving column (10) is fixedly mounted on the outer surface of one side of the turntable (8). The driving column (10) is arranged at an eccentric position of the turntable (8). A connecting rod (9) is rotatably mounted on the outer surface of the driving column (10), and the other end of the connecting rod (9) is rotatably mounted to the outer surface of the center position of the piston plate (30).

6. The veterinary drug detection sample preparation device according to claim 1, characterized in that: The lower surface of the shell (2) is provided with a through hole, the inner wall of the through hole is threadedly connected to a discharge barrel (18), a conical plate is fixedly installed on the inner wall of the discharge barrel (18) near the bottom end, and a liquid outlet hole (20) is penetrated through the outer surface of the middle position of the conical plate, a sliding column is slidably inserted at the top end of the discharge barrel (18), a floating plate (21) is fixedly installed at the top end of the sliding column, and a plug (22) is fixedly installed through the top wall of the discharge barrel (18) at the bottom end of the sliding column, the outer surface of the plug (22) is against the inner wall of the liquid outlet hole (20), and the circumferential outer surface of the discharge barrel (18) is penetrated A plurality of liquid inlet holes (19) are provided, wherein the liquid inlet holes (19) are arranged inside the shell (2); a spring plunger (24) is fixedly mounted on the inner wall of the discharge barrel (18); a steel ball (31) is slidably mounted on the inner wall of the spring plunger (24) near the top end; the steel ball (31) abuts against the outer surface of the sliding column; a spring (32) is arranged inside the spring plunger (24); the spring (32) is arranged between the steel ball (31) and the spring plunger (24); a groove (23) is provided on the circumferential outer surface of the sliding column; the steel ball (31) is arranged to match the inner wall of the groove (23).

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