Cosmetic composition containing hydroxylated tyrosol and method for its preparation and use

Abstract

The present application relates to a kind of hydroxyl tyrosol-containing cosmetic compositions and its preparation method and application, the cosmetic composition includes continuous phase oil phase and dispersed phase alcohol phase dispersed in oil phase;The component of the oil phase includes ester oil and lecithin;The component of the alcohol phase includes dipropylene glycol, antioxidant and hydroxyl tyrosol;The antioxidant includes ascorbic acid.The present application is creatively dissolved with dipropylene glycol to ascorbic acid and hydroxyl tyrosol simultaneously to form alcohol phase;Ester oil is selected to be dissolved to lecithin to form oil phase, and alcohol phase is dispersed in oil phase.The system can make that hydroxyl tyrosol is not easily oxidized and deteriorated and discolored, has higher protection to the antioxidant activity of hydroxyl tyrosol, even when high temperature and light can maintain color stability and efficacy stability, the cosmetic composition can be used as cosmetic raw material and added to other systems, can also be used as oil product directly.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of cosmetics, and relates to a cosmetic composition containing hydroxytyrosol and a preparation method and application thereof. BACKGROUND

[0002] Hydroxytyrosol is a natural polyphenol compound mainly in the form of esters in the fruits and branches of olives, and can be derived from olive oil and wastewater generated in the processing of olive oil. At present, some are also biosynthesized by genetic engineering, and its chemical name is dihydroxyphenethyl alcohol.

[0003] Hydroxytyrosol has various biological and pharmacological activities, such as beneficial effects on bone growth and function, helps the human body to absorb minerals, does not need to supplement calcium, naturally absorbs, maintains bone density, reduces bone osteoporosis, at the same time improves the function of the endocrine system, promotes metabolism, promotes wound healing, eliminates free radicals in the body, restores the health status of human visceral organs, prevents brain decay, delays aging, and maintains youth vitality; can also intervene in lung cancer, breast cancer, uterine cancer, prostate cancer, etc., promote recovery and improve the effect of chemotherapy in the later stage of cancer; prevent and treat various diseases caused by smoking; and has preventive and therapeutic effects on arteriosclerosis, hypertension, heart disease, cerebral hemorrhage, etc. Hydroxytyrosol applied to cosmetics can effectively enhance skin elasticity and moisturizing, and has the effects of antioxidant and anti-wrinkle anti-aging.

[0004] However, due to the structural characteristics of phenolic hydroxyl and alcoholic hydroxyl of hydroxytyrosol itself, it is extremely easy to be oxidized and discolored. It is also unstable at room temperature, which limits its application. The existing technology also lacks effective solutions to the above problems, for example, the traditional oil-in-water or water-in-oil emulsion cannot maintain the stability of hydroxytyrosol for a long time, especially at high temperature. SUMMARY

[0005] In view of the deficiencies of the prior art, the purpose of the present application is to provide a cosmetic composition containing hydroxytyrosol and a preparation method and application thereof in cosmetics.

[0006] To achieve the purpose of the present application, the following technical solutions are adopted:

[0007] In a first aspect, the present application provides a cosmetic composition containing hydroxytyrosol, which comprises a continuous phase oil phase and a dispersed phase alcohol phase dispersed in the oil phase; the components of the oil phase include ester oil and lecithin; the components of the alcohol phase include dipropylene glycol, an antioxidant and hydroxytyrosol; the antioxidant includes ascorbic acid.

[0008] The application creatively uses dipropylene glycol to dissolve ascorbic acid and hydroxytyrosol simultaneously to form an alcohol phase; selects lecithin to dissolve ester oil to form an oil phase, and the alcohol phase is dispersed in the oil phase. The system can prevent hydroxytyrosol from being oxidized, discolored and deteriorated, has a high protective effect on the antioxidant activity of hydroxytyrosol, can maintain color stability and efficacy stability even under high temperature and light, has a slow-release effect on hydroxytyrosol, and can be used as a cosmetic raw material added to other systems or directly used as an oil product. The cosmetic composition widens the application scenarios of hydroxytyrosol.

[0009] Preferably, the cosmetic composition comprises a continuous phase oil phase 95-99.5% and a dispersed phase alcohol phase 0.5-5% dispersed in the oil phase by mass percentage.

[0010] The oil phase and the alcohol phase are mixed in a specific ratio, and the system prepared thereby is an alcohol-in-oil reverse micelle system, and the reverse micelle system is different from the traditional reverse micelle system, the inner phase of the traditional reverse micelle system is a water phase, and the inner phase of the reverse micelle system of the application is an alcohol phase. The system has low viscosity, transparency, kinetic stability, small particle size of alcohol droplets dispersed in the oil phase, and higher skin permeability.

[0011] The mass percentage of the oil phase can be selected from 95%, 95.5%, 96%, 96.5%, 97%, 97.5%, 98%, 98.5%, 99%, 99.5%, etc.

[0012] The mass percentage of the alcohol phase can be selected from 0.5%, 1%, 1.5%, 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, 5%, etc.

[0013] Other specific point values within the above numerical ranges can be selected, which will not be described here.

[0014] Preferably, the mass percentages of the dipropylene glycol, hydroxytyrosol and antioxidant in the cosmetic composition are 0.5-4%, 0.001-3% and 0.0001-0.5%, respectively.

[0015] When the dipropylene glycol, hydroxytyrosol and antioxidant satisfy the above specific mass ratio relationship, the system of the cosmetic composition is more stable, and the efficacy of hydroxytyrosol can be better exerted.

[0016] The mass percentage of the dipropylene glycol in the cosmetic composition can be selected as 0.5%, 1%, 1.5%, 2%, 2.5%, 3%, 3.5%, 4%, etc.; the mass percentage of the hydroxytyrosol in the cosmetic composition can be selected as 0.001%, 0.01%, 0.05%, 0.1%, 0.5%, 1%, 1.5%, 2%, 2.5%, 3%, etc.; and the mass percentage of the antioxidant in the cosmetic composition can be selected as 0.001%, 0.01%, 0.05%, 0.1%, 0.2%, 0.3%, 0.4%, 0.5%, etc.

[0017] Other specific point values within the above-mentioned numerical ranges can be selected, which will not be repeated here.

[0018] Preferably, the mass percentage of the ester oil and lecithin in the cosmetic composition is 70-99% and 0.1-5%, respectively.

[0019] When the ester oil and lecithin satisfy the above-mentioned specific mass ratio relationship, the system of the cosmetic composition is more stable, and the efficacy of hydroxytyrosol can be better exerted.

[0020] The mass percentage of the ester oil in the cosmetic composition can be selected as 70%, 75%, 78%, 80%, 82%, 85%, 90%, 99%, etc.

[0021] The mass percentage of the lecithin in the cosmetic composition can be selected as 0.1%, 0.5%, 1%, 1.5%, 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, 5%, etc.

[0022] Other specific point values within the above-mentioned numerical ranges can be selected, which will not be repeated here.

[0023] Preferably, the ester oil includes any one or a combination of at least two of caprylic / capric triglyceride, glyceryl tri(ethylhexanoate), or isononyl isononanoate.

[0024] Preferably, the combination of the oil phase further includes tocopheryl acetate.

[0025] The further addition of the oil-soluble oxidant tocopheryl acetate in the oil phase can improve the stability of hydroxytyrosol in the system, and the hydroxytyrosol is less likely to deteriorate and discolor, further improving the stability of efficacy.

[0026] Preferably, the mass percentage of the tocopheryl acetate in the cosmetic composition is 0.01-0.5%, for example 0.01%, 0.05%, 0.1%, 0.15%, 0.2%, 0.25%, 0.3%, 0.35%, 0.45%, 0.5%, and other specific point values within the numerical range can be selected, which will not be repeated here.

[0027] Preferably, the antioxidant of the alcohol phase component further comprises hydroxymethoxyphenyl decyl ketone.

[0028] Further adding the antioxidant hydroxymethoxyphenyl decyl ketone and ascorbic acid in the alcohol phase can further improve the stability of hydroxytyrosol in the system, making it more difficult to deteriorate and discolor, and further improving the stability of the efficacy.

[0029] Preferably, the mass ratio of the hydroxymethoxyphenyl decyl ketone to ascorbic acid is 1:(1-20), for example 1:1, 1:2, 1:3, 1:4, 1:5, 1:7, 1:10, 1:12, 1:14, 1:16, 1:18, 1:20, and other specific point values within the numerical range can be selected, which will not be repeated here.

[0030] In a second aspect, the present application provides a preparation method of the hydroxytyrosol-containing cosmetic composition according to the first aspect, the preparation method comprising:

[0031] Mixing and dissolving the dipropylene glycol, the antioxidant, and the hydroxytyrosol to prepare an alcohol phase solution;

[0032] Mixing and dissolving the ester oil and lecithin to prepare an oil phase solution;

[0033] Slowly adding the alcohol phase solution to the oil phase solution under stirring, and continuing to stir to obtain the hydroxytyrosol-containing cosmetic composition.

[0034] Preferably, the tocopheryl acetate is further mixed and dissolved when preparing the oil phase solution.

[0035] Preferably, the mixing and dissolving for preparing the oil phase solution is carried out at 80-90°C (for example 80°C, 82°C, 84°C, 86°C, 87°C, 88°C, 90°C, etc.) for 30-60 min (for example 30 min, 35 min, 40 min, 45 min, 50 min, 55 min, 60 min, etc.).

[0036] Preferably, the mixing and dissolving for preparing the alcohol phase solution is carried out at 35-45°C (for example 35°C, 36°C, 37°C, 38°C, 40°C, 42°C, 45°C, etc.) for 30-60 min (for example 30 min, 35 min, 40 min, 45 min, 50 min, 55 min, 60 min, etc.).

[0037] Preferably, the stirring is continued at 35-45℃ (e.g. 35℃, 36℃, 37℃, 38℃, 40℃, 42℃, 45℃, etc.) for 30-60min (e.g. 30min, 35min, 40min, 45min, 50min, 55min, 60min, etc.).

[0038] Other specific point values within the above-mentioned numerical ranges can also be selected, which will not be repeated here.

[0039] In a third aspect, the present application provides use of the hydroxylated troxerutin cosmetic composition according to the first aspect in the preparation of a cosmetic.

[0040] Compared with the prior art, the present application has the following beneficial effects:

[0041] The present application creatively uses dipropylene glycol to simultaneously dissolve ascorbic acid and hydroxylated troxerutin to form an alcohol phase; an ester oil is selected to dissolve lecithin to form an oil phase, and the alcohol phase is dispersed in the oil phase. The system can prevent the hydroxylated troxerutin from being oxidized, discolored and deteriorated, has a high protective effect on the antioxidant activity of the hydroxylated troxerutin, can maintain color stability and efficacy stability even under high temperature and light, has a slow-release effect on the hydroxylated troxerutin, and can be used as a cosmetic raw material added to other systems or directly used as an oil product. The cosmetic composition widens the application scenarios of the hydroxylated troxerutin.

[0042] The oil phase and the alcohol phase are mixed in a specific ratio in the present application, and the prepared system is an alcohol-in-oil reverse micelle system. The reverse micelle system is different from the traditional reverse micelle system, in which the internal phase is a water phase, while the internal phase of the reverse micelle system of the present application is an alcohol phase. The system has low viscosity, transparency, kinetic stability, small particle size of alcohol droplets dispersed in the oil phase, and higher skin permeability. DETAILED DESCRIPTION

[0043] In order to further illustrate the technical means adopted by the present application and its effects, the technical solutions of the present application will be further described below in combination with preferred embodiments of the present application, but the present application is not limited in the scope of the embodiments.

[0044] The mass percentage contents of the lecithin, tocopheryl acetate, caprylic / capric triglyceride, glyceryl tri(ethylhexanoate), isononyl isononanoate, dipropylene glycol, ascorbic acid, hydroxymethoxyphenyl decyl ketone and hydroxylated troxerutin described below are calculated based on the actual active ingredient content contained in the commercially available raw materials. The commercially available raw materials also selectively contain any one or a combination of at least two of solvents, fillers, diluents, stabilizers, pH regulators, antibacterial agents, antioxidants or impurities within the permissible range.

[0045] Example 1

[0046] This example provides a cosmetic composition comprising the following components, based on a total amount of 100%: (alcohol phase) dipropylene glycol 0.8%, ascorbic acid 0.008%, hydroxytyrosol 0.5%; (oil phase): lecithin 2%, glyceryl tri(ethylhexanoate) 20%, isononyl isononanoate 6%, caprylic / capric triglyceride remainder;

[0047] The preparation method is as follows:

[0048] (1) At 40°C, add ascorbic acid to dipropylene glycol, mix for 30 min until completely dissolved, in a transparent state; then add hydroxytyrosol, mix for 20 min until completely dissolved, to prepare an alcohol phase solution;

[0049] (2) Mix glyceryl tri(ethylhexanoate), isononyl isononanoate, caprylic / capric triglyceride, and lecithin at 85°C for 40 min, cool to 40°C, to prepare an oil phase solution;

[0050] (3) Slowly add the alcohol phase solution to the oil phase solution under stirring, continue stirring for 40 min, to obtain a hydroxytyrosol-containing cosmetic composition in a transparent state.

[0051] Example 2

[0052] This example provides a cosmetic composition comprising the following components, based on a total amount of 100%: (alcohol phase) dipropylene glycol 2%, ascorbic acid 0.02%, hydroxytyrosol 1%; (oil phase): lecithin 3%, glyceryl tri(ethylhexanoate) 15%, isononyl isononanoate 10%, caprylic / capric triglyceride remainder;

[0053] The preparation method is as follows:

[0054] (1) At 35°C, add ascorbic acid to dipropylene glycol, mix for 40 min until completely dissolved, in a transparent state; then add hydroxytyrosol, mix for 20 min until completely dissolved, to prepare an alcohol phase solution;

[0055] (2) Mix glyceryl tri(ethylhexanoate), caprylic / capric triglyceride, and lecithin at 80°C for 60 min, cool to 35°C, to prepare an oil phase solution;

[0056] (3) Slowly add the alcohol phase solution to the oil phase solution under stirring, continue stirring for 60 min, to obtain a hydroxytyrosol-containing cosmetic composition in a transparent state.

[0057] Example 3

[0058] The present example provides a cosmetic composition comprising the following components: (alcohol phase) dipropylene glycol 2.5%, ascorbic acid 0.02%, hydroxytyrosol 2%; (oil phase): glyceryl tri(ethylhexanoate) 30%, isononyl isononanoate 15%, caprylic / capric triglyceride remainder;

[0059] The preparation method is as follows:

[0060] (1) At 45°C, add ascorbic acid into dipropylene glycol, mix for 30 min until completely dissolved, in a transparent state; then add hydroxytyrosol, mix for 20 min until completely dissolved, to prepare alcohol phase solution;

[0061] (2) Mix isononyl isononanoate, caprylic / capric triglyceride and lecithin at 90°C for 30 min, cool to 45°C, to prepare oil phase solution;

[0062] (3) Slowly add alcohol phase solution into oil phase solution under stirring, continue stirring for 30 min, to obtain hydroxytyrosol-containing cosmetic composition in a transparent state.

[0063] Example 4

[0064] The present example provides a cosmetic composition, the components of which differ from those of Example 1 only in that the oil phase further contains tocopheryl acetate.

[0065] The present example provides a cosmetic composition comprising the following components: (alcohol phase) dipropylene glycol 0.8%, ascorbic acid 0.01%, hydroxytyrosol 0.5%; (oil phase): lecithin 2%, tocopheryl acetate 0.4%, glyceryl tri(ethylhexanoate) 20%, isononyl isononanoate 6%, caprylic / capric triglyceride remainder;

[0066] The preparation method is as follows:

[0067] (1) At 40°C, add ascorbic acid into dipropylene glycol, mix for 30 min until completely dissolved, in a transparent state; then add hydroxytyrosol, mix for 20 min until completely dissolved, to prepare alcohol phase solution;

[0068] (2) Mix glyceryl tri(ethylhexanoate), isononyl isononanoate, caprylic / capric triglyceride and lecithin at 85°C for 40 min, cool to 40°C, then add tocopheryl acetate to dissolve, to prepare oil phase solution;

[0069] (3) Slowly add alcohol phase solution into oil phase solution under stirring, continue stirring for 40 min, to obtain hydroxytyrosol-containing cosmetic composition in a transparent state.

[0070] Example 5

[0071] The present example provides a cosmetic composition, the components of which differ from those of Example 1 only in that the alcohol phase also contains hydroxymethoxyphenyl decyl ketone.

[0072] It comprises the following components (in 100% total): (alcohol phase) dipropylene glycol 0.8%, ascorbic acid 0.006%, hydroxymethoxyphenyl silicone 0.002%, hydroxytyrosol 0.5%; (oil phase): lecithin 2%, glyceryl tri(ethylhexanoate) 20%, isononyl isononanoate 6%, caprylic / capric acid triglyceride remainder;

[0073] The preparation method is as follows:

[0074] (1) At 40°C, the ascorbic acid and hydroxymethoxyphenyl decyl ketone are added to the dipropylene glycol, mixed for 30 min until completely dissolved, in a transparent state; then the hydroxytyrosol is added, mixed for 20 min until completely dissolved, to obtain an alcohol phase solution;

[0075] (2) The glyceryl tri(ethylhexanoate), isononyl isononanoate, caprylic / capric acid triglyceride and lecithin are mixed at 85°C for 40 min, cooled to 40°C, to obtain an oil phase solution;

[0076] (3) The alcohol phase solution is slowly added to the oil phase solution under stirring, continue to stir for 40 min, to obtain a hydroxytyrosol-containing cosmetic composition in a transparent state.

[0077] Example 6

[0078] The present example provides a cosmetic composition, the components of which differ from those of Example 1 only in that the glyceryl tri(ethylhexanoate) is not contained, and its mass is distributed to the mass of isononyl isononanoate. The others remain unchanged.

[0079] The preparation method is referred to Example 1.

[0080] Example 7

[0081] The present example provides a cosmetic composition, the components of which differ from those of Example 1 only in that the isononyl isononanoate is not contained, and its mass is distributed to the mass of glyceryl tri(ethylhexanoate). The others remain unchanged.

[0082] The preparation method is referred to Example 1.

[0083] Comparative Example 1

[0084] The present comparative example provides a cosmetic composition, the components of which differ from those of Example 1 only in that the ascorbic acid is replaced by hydroxymethoxyphenyl decyl ketone in equal mass, and the others remain unchanged.

[0085] The preparation method is referred to Example 1.

[0086] Comparative Example 2

[0087] This comparative example provides a cosmetic composition whose components differ from those of Example 1 only in that the dipropylene glycol is replaced by 1,3-butanediol in equal mass, with the other components remaining unchanged.

[0088] Comparative Example 3

[0089] This comparative example provides a cosmetic composition whose components differ from those of Example 1 only in that the dipropylene glycol is replaced by 1,3-propanediol in equal mass, with the other components remaining unchanged.

[0090] Comparative Example 4

[0091] This example provides a cosmetic composition whose components differ from those of Example 1 only in that ascorbic acid is absent, with the reduced mass being made up by caprylic / capric triglyceride, with the other components remaining unchanged.

[0092] Comparative Example 5

[0093] This example provides a cosmetic composition which is an emulsion system rather than a reverse micelle system, which differs from Example 1.

[0094] Its components include the following, based on a total of 100%: (alcohol phase) dipropylene glycol 10%, ascorbic acid 0.01%, hydroxytyrosol 0.5%; (oil phase): lecithin 3%, glyceryl tri(ethylhexanoate) 20%, isononyl isononanoate 6%, caprylic / capric triglyceride to make up the balance;

[0095] Its preparation method is as follows:

[0096] (1) At 40°C, add ascorbic acid to dipropylene glycol, mix for 30 min until completely dissolved, and present in a transparent state; then add hydroxytyrosol, mix for 20 min until completely dissolved, to produce an alcohol phase solution;

[0097] (2) Mix glyceryl tri(ethylhexanoate), isononyl isononanoate, caprylic / capric triglyceride and lecithin at 85°C for 40 min, cool to 40°C, to produce an oil phase solution;

[0098] (3) Slowly add the alcohol phase solution to the oil phase solution under stirring, continue stirring for 40 min, and it is obtained.

[0099] Test Example 1

[0100] Hydroxytyrosol stability:

[0101] The retention rate and discoloration of hydroxytyrosol in the cosmetic compositions produced in Examples 1-7 and Comparative Examples 1-5 were evaluated for changes over time after storage for 90 days at 25°C, 45°C, and under light (daylight) conditions.

[0102] The method for detecting the retention rate of hydroxytyrosol is as follows:

[0103] (1) Prepare 0.2, 0.5, 1.0, 1.3, 1.5 mg / mL hydroxytyrosol methanol solutions respectively, and determine the absorbance values by using a UV spectrophotometer to obtain a hydroxytyrosol standard curve;

[0104] (2) Store the cosmetic compositions prepared in Examples 1-7 and Comparative Examples 1-5 under different conditions, and take a small amount of sample at regular time intervals, dilute with methanol to make the absorbance fall within the range of 0.2-0.6, and determine the absorbance values by using a UV spectrophotometer, and then compare with the hydroxytyrosol standard curve and multiply by the dilution factor to obtain the hydroxytyrosol content in the cosmetic composition;

[0105] (3) Calculate the retention rate of hydroxytyrosol: the retention rate of hydroxytyrosol (%) = the hydroxytyrosol content on the 90th day / the hydroxytyrosol content on the 0th day x 100%.

[0106] The results are shown in Table 1:

[0107] Table 1

[0108]

[0109] The discoloration of the samples in each group after being stored at 25℃, 45℃ and under light for 90 days is shown in Table 2:

[0110] Table 2

[0111]

[0112]

[0113] Note: The discoloration from light to heavy is as follows: no discoloration-mild discoloration-general discoloration-moderate discoloration-severe discoloration;

[0114] From the results in Table 1 and Table 2, it can be seen that, compared with the emulsion system of Comparative Example 5, the cosmetic composition involved in the present application has significantly excellent color stability and component stability, and the retention rate of hydroxytyrosol therein can still be maintained at a high level after being stored for 90 days under normal temperature, high temperature or light conditions, and the addition of ascorbic acid in the alcohol phase plays an important role in the stability of hydroxytyrosol, and the selection of the polyhydric alcohol dipropylene glycol also has an important positive effect on the stability of hydroxytyrosol.

[0115] Test Example 2

[0116] Antioxidant activity stability:

[0117] The DPPH scavenging test was carried out on the cosmetic compositions prepared in Examples 1-7 and Comparative Examples 1-5 under accelerated conditions (45℃) to characterize the antioxidant activity stability of each sample.

[0118] (1) Prepare 0.3 mM DPPH solution in methanol; dissolve each group of samples in methanol to prepare sample solutions with a concentration of 20%;

[0119] (2) Set up sample group, control group and blank group; wherein the sample group: take 100 μL sample solution to a 96-well plate, and add 100 μL DPPH solution, react for 30 min, and detect absorbance As at 517 nm by UV-visible spectrophotometer; wherein the control group: take 100 μL methanol to a 96-well plate, and add 100 μL DPPH solution, react for 30 min, and detect absorbance Ac at 517 nm; wherein the blank group: take 100 μL sample solution to a 96-well plate, and add 100 μL methanol solution, react for 30 min, and detect absorbance Asb at 517 nm;

[0120] DPPH free radical scavenging rate (%) = [1-(As-Asb) / Ac] x 100%;

[0121] DPPH free radical scavenging rate retention rate (%) = D n / D0, D n and D0 are the DPPH free radical scavenging rate of the sample on the n th day at 45℃ and the DPPH free radical scavenging rate of the sample on the 0 th day, respectively.

[0122] The results are shown in Table 3:

[0123] Table 3

[0124] Group 30-day clearance retention rate (%) 60-day clearance retention rate (%) Example 1 88.3 84.5 Example 2 87.2 84.3 Example 3 89.3 85.2 Example 4 90.5 87.3 Example 5 92.5 88.9 Example 6 86.3 83.2 Example 7 85.6 83.9 Comparative Example 1 77.3 65.3 Comparative Example 2 83.5 79.2 Comparative Example 3 82.6 78.4 Comparative Example 4 68.6 48.3 Comparative Example 5 51.0 32.5

[0125] From the data in Table 3, it can be seen that the cosmetic composition involved in the present application has significantly excellent efficacy stability compared with the emulsion system of Comparative Example 5, wherein the antioxidant activity of hydroxytyrosol therein can still be maintained at a high level after being stored at high temperature for 60 days, and the addition of ascorbic acid in the alcohol phase plays an important role in the stability of hydroxytyrosol, and the selection of the polyhydric alcohol dipropylene glycol also has an important positive effect on the stability of hydroxytyrosol.

[0126] The applicant declares that the technical solutions of the present application are illustrated by the above examples, but the present application is not limited to the above examples, i.e. it does not mean that the present application must rely on the above examples to be implemented. It should be understood by those skilled in the art that any improvement of the present application, equivalent replacement of each raw material of the product of the present application, addition of auxiliary ingredients, selection of specific modes, etc. fall within the protection scope and disclosure scope of the present application.

[0127] The preferred embodiments of the present application are described in detail above, but the present application is not limited to the specific details of the above-described embodiments, and various simple modifications can be made to the technical solutions of the present application within the technical concept of the present application, and these simple modifications all belong to the protection scope of the present application.

[0128] In addition, it should be noted that each specific technical feature described in the above specific embodiments can be combined in any appropriate manner without contradiction, and in order to avoid unnecessary repetition, various possible combinations are not described again by the present application.

Claims

1. A cosmetic composition containing hydroxytyrosol, characterized in that, The cosmetic composition comprises, in mass percentage, a continuous phase oil phase 95-99.5% and a dispersed phase alcohol phase 0.5-5% dispersed in the oil phase; The components of the oil phase include ester oil, lecithin and tocopheryl acetate; the mass percentage of the ester oil and lecithin in the cosmetic composition is 90.0-99.0% and 0.5-5% respectively; The ester oil is caprylic / capric triglyceride and glyceryl tri(ethylhexanoate), caprylic / capric triglyceride and isononyl isononanoate, or a combination of caprylic / capric triglyceride, glyceryl tri(ethylhexanoate) and isononyl isononanoate; The components of the alcohol phase include dipropylene glycol, an antioxidant and hydroxytyrosol; the mass percentage of the dipropylene glycol, hydroxytyrosol and antioxidant in the cosmetic composition is 0.5-4%, 0.1-3% and 0.008-0.2% respectively; The antioxidant consists of ascorbic acid and hydroxymethoxyphenyl decyl ketone; the mass ratio of hydroxymethoxyphenyl decyl ketone to ascorbic acid is 1:3; the composition is an alcohol-in-oil reverse micelle system.

2. The hydroxyl-containing tyrosol cosmetic composition according to claim 1, characterized in that, The mass percentage of the tocopheryl acetate in the cosmetic composition is 0.01-0.5%.

3. The method for producing a hydroxytyrosol-containing cosmetic composition according to any one of claims 1-2, characterized by, The preparation method comprises: Mixing and dissolving dipropylene glycol, an antioxidant and hydroxytyrosol to prepare an alcohol phase solution; Mixing and dissolving ester oil, lecithin and tocopheryl acetate to prepare an oil phase solution; Adding the alcohol phase solution to the oil phase solution under stirring, and continuing to stir to obtain the hydroxytyrosol-containing cosmetic composition.

4. The method for producing a hydroxytyrosol-containing cosmetic composition according to claim 3, characterized by, The mixing and dissolving in the preparation of the oil phase solution is performed at 80-90°C for 30-60 min.

5. The method for preparing a hydroxytyrosol-containing cosmetic composition according to claim 3, characterized by, The mixing and dissolving in the preparation of the alcohol phase solution is performed at 35-45°C for 30-60 min.

6. The method for preparing a hydroxytyrosol-containing cosmetic composition according to claim 3, characterized by, The continuing stirring is performed at 35-45°C for 30-60 min.

7. Use of the hydroxytyrosol-containing cosmetic composition according to any one of claims 1-2 in the preparation of a cosmetic.

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