A fat-reducing composition containing plant extract ingredients and preparation method thereof

By using fat-reducing compositions containing plant extract ingredients in fat-reducing products, and using the synergistic effects of a variety of plant extracts, the problem of temporary and unsafe effects of existing fat-reducing products is solved, and a safe and long-term fat-reducing effect is achieved.

CN119015387BActive Publication Date: 2025-03-21GUANGDONG SANHE BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202411142288.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-08-20
Publication Date
2025-03-21
Estimated Expiration
2044-08-20

AI Technical Summary

Technical Problem

Existing fat-reducing products use appetite suppression as the main method, which has temporary effects and may cause adverse reactions, lacking safety and long-term effects.

Method used

Using a fat-reducing composition containing plant extract ingredients, through the optimization of the preparation process, plant extracts such as okra extract, berberine extract, gambola extract, bitter gourd extract, gourd extract, licorice extract, ginger extract, green tea extract, cactus extract and other plant extracts are compounded with appropriate mass ratios to ensure the synergistic effect between the extracts and jointly promote human health.

Benefits of technology

Through the synergistic effect of plant extracts, the cholesterol and triglyceride levels in the blood are effectively reduced, the accumulation of body fat is reduced, the basal metabolic rate is improved, the oxidative decomposition of fat is promoted, the feeling of fullness is increased, the blood sugar level is regulated, and the intestinal flora balance is improved, thereby achieving a safe and long-term fat loss effect.

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Abstract

The invention discloses a fat-reducing composition containing plant extract ingredients and a preparation method thereof, and belongs to the technical field of fat-reducing compositions. The method comprises the following steps: mixing starch, disodium hydrogen phosphate, citric acid, and deionized water, adding α-amylase, adjusting pH, centrifuging, and treating the solid phase to obtain material A; mixing material A, sodium alginate, Dendrobium officinale extract, and deionized water to obtain material B; mixing pig liver powder, cuttlebone powder, gluconolactone, sucrose fatty acid ester, and deionized water, adding material B, heating to 85-95°C, adding plant extracts, homogenizing, and spray drying to obtain a fat-reducing composition containing plant extract ingredients with good lipid-lowering effect.
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Description

Technical Field

[0001] The invention belongs to the technical field of fat-reducing compositions, and in particular relates to a fat-reducing composition containing plant extract ingredients and a preparation method thereof. Background Art

[0002] With the progress of society and economic development, people's living standards have been significantly improved. At the same time, the pace of life has become faster and faster. In this context, people's daily diet has become more and more diverse and rich, and the intake of various high-fat, high-protein and other nutrients has also increased significantly. However, this excessive energy intake has become one of the main causes of overweight and obesity. The emergence of obesity has significantly increased the probability of health problems such as high blood pressure, high blood sugar, and high blood lipids.

[0003] Among the fat-reducing products currently on the market, most use appetite suppression as the main means. Although this method can effectively control weight in a short period of time, its effect is often only temporary. More seriously, long-term use of these products may cause a series of adverse reactions, such as acid reflux, arrhythmia, diarrhea, anxiety, insomnia and other symptoms. These side effects not only affect people's quality of life, but also make the safety and effectiveness of these fat-reducing products questionable. Therefore, finding a method that can effectively reduce fat while ensuring safety and long-term effects has become an urgent problem to be solved in the current health field. Summary of the invention

[0004] The object of the present invention is to provide a fat-reducing composition containing plant extract ingredients and a preparation method thereof, so as to provide a healthy fat-reducing composition and improve the fat-reducing effect.

[0005] The purpose of the present invention can be achieved by the following technical solutions:

[0006] A method for preparing a fat-reducing composition containing plant extract ingredients, comprising the following steps:

[0007] S1. Mix starch, disodium hydrogen phosphate, citric acid and deionized water, stir at 50°C for 10-20 min, add α-amylase, continue stirring for 30-40 min, adjust the pH to 6-7, centrifuge, dry the solid phase, grind, and sieve with an 80-100 mesh screen to obtain material A;

[0008] S2, mixing the material A, sodium alginate, Dendrobium officinale extract and deionized water, and stirring for 10-12 hours to obtain material B;

[0009] S3. Mix pork liver powder, cuttlebone powder, gluconolactone, sucrose fatty acid ester and deionized water, stir at 70° C. for 20-30 min, cool to 45-55° C., add material B, ultrasonically disperse for 2-3 min, heat to 85-95° C., stir for 1-2 min, add plant extract, homogenize, and spray dry to obtain the fat-reducing composition.

[0010] As a preferred technical solution of the present invention, in step S1, the mass ratio of starch, disodium hydrogen phosphate, citric acid, deionized water and α-amylase is 20-24: 0.56-0.58: 0.35-0.38: 60-80: 0.06-0.08.

[0011] As a preferred technical solution of the present invention, the various dendrobiums contained in the Dendrobium officinale extract lock the volatile substances in the plant extract through the л-л effect, thereby increasing the retention of nutrients in the plant extract. At the same time, the Dendrobium officinale extract regulates blood sugar and fat metabolism, lowers cholesterol and triglycerides in the blood, thereby helping to reduce the synthesis and accumulation of fat in the body.

[0012] As a preferred technical solution of the present invention, pig liver powder and cuttlebone powder provide trace metal elements, lock the volatile components in the plant extracts through chelation, and regulate the endocrine balance of people who want to lose weight.

[0013] As a preferred technical solution of the present invention, in step S2, the mass ratio of material A, sodium alginate, Dendrobium officinale extract and deionized water is 6-8:1-1.5:0.1-0.2:50.

[0014] As a preferred technical solution of the present invention, in step S3, the mass ratio of the pig liver powder, cuttlebone powder, gluconolactone, sucrose fatty acid ester, deionized water, material B, and plant extract is 1-2:1-2:0.05:0.05:200:10-12:30-40.

[0015] As a preferred technical solution of the present invention, the method for preparing the plant extract comprises the following steps:

[0016] A1. Wash fresh okra, put it into an extraction tank, add 10 times the amount of distilled water and boil for extraction three times, combine the extracts, concentrate and dry until the mass proportion of distilled water in the extract is less than 8%, spray dry, crush, and pass through a 100-mesh sieve to obtain an okra extract;

[0017] A2, washing fresh yam, peeling, pressing the pulp, filtering, and extracting the juice to obtain yam extract;

[0018] A3, washing fresh garcinia cambogia, peeling, pressing the pulp, filtering, and extracting the juice to obtain garcinia cambogia extract;

[0019] A4, washing and peeling fresh bitter melon, pressing the pulp, filtering, and extracting the juice to obtain bitter melon extract;

[0020] A5. Wash and slice fresh gourd, immerse in 5 times the amount of distilled water and heat to boiling, continue to cook for 80-100 min, filter, take the liquid phase, and obtain gourd extract;

[0021] A6. Take the okra extract, mountain mushroom extract, garcinia cambogia extract, bitter melon extract, gourd extract, licorice extract (purchased from Xinxiang Bokai Biotechnology Co., Ltd.), ginger extract (purchased from Shaanxi Xinyanghe Biotechnology Co., Ltd.), green tea extract (purchased from Nanjing Zhenweikang Biotechnology Co., Ltd.), cactus extract (purchased from Shaanxi Xinyanghe Biotechnology Co., Ltd.), deionized water, mix, and ultrasonically disperse for 20-30 minutes to obtain the plant extract.

[0022] As a preferred technical solution of the present invention, in step A6, the mass ratio of the okra extract, mountain mushroom extract, garcinia cambogia extract, bitter melon extract, gourd extract, licorice extract, ginger extract, green tea extract, cactus extract, and deionized water is 15-22:20-30:8-10:5-7:2-3:0.6-0.8:0.1-0.3:1-2:1-2:50.

[0023] As a preferred technical solution of the present invention, in step S3, the atomization pressure of the spray drying is 70-90 bar, and the temperature of the spray drying is 80-110°C.

[0024] As a preferred technical solution of the present invention, in step S3, the homogenizing refers to homogenizing at a speed of 3000-4000 r / min for 2-3 min.

[0025] As a preferred technical solution of the present invention, in step A1, the atomization pressure of the spray drying is 100 bar, and the temperature of the spray drying is 120-140°C.

[0026] As a preferred technical solution of the present invention, the phytochemicals contained in the okra extract, such as sticky polysaccharides, oligosaccharides and bioactive peptides, help to lower the cholesterol and triglyceride levels in the blood, thereby reducing the deposition of fat in the blood vessel walls, reducing the accumulation of fat in the body, increasing the body's basal metabolic rate, promoting the oxidative decomposition of fat, increasing satiety, regulating blood sugar levels, and improving the balance of intestinal flora, thereby playing a role in reducing fat;

[0027] The extract of the mountain mushroom contains a variety of organic acids, such as ursolic acid and oleanolic acid, which can promote the decomposition of fat by activating the lipolytic enzyme in fat cells, thereby reducing the accumulation of fat in the body;

[0028] The hydroxycitric acid contained in Garcinia Cambogia Extract can inhibit fat synthesis, promote gluconeogenesis, improve insulin sensitivity, lower blood cholesterol levels, help promote gastrointestinal motility, improve digestive function, promote defecation for people who want to lose weight, and form a good internal circulation;

[0029] Bitter melon extract reduces fat absorption through bitter melon and other fiber components, increases the viscosity of gastric contents and slows digestion to increase satiety, and improves metabolic rate and electrolyte balance through vitamin C and other minerals;

[0030] The vitamin C, carotene and B vitamins in gourd seed extract play an important role in the process of fat loss. Vitamin C is an essential component for the synthesis of carnitine. Carnitine can transfer fatty acids from the cytoplasm to the mitochondria for oxidation and combustion, which can reduce the production of free radicals and protect cells from oxidative stress. Maintaining a healthy immune system helps the body resist disease, thereby reducing the slowing of metabolism and weight gain caused by disease. Carotene can be converted into vitamin A in the body. Vitamins A and B participate in fat metabolism and hormone synthesis, which helps maintain the health of muscles and connective tissues and relieve the problems of loose and wrinkled skin caused by fat loss.

[0031] During the weight loss process, licorice extract is used to regulate blood sugar fluctuations caused by reduced nutrient intake, enhance immune function, regulate water balance in the body, and have anti-stress effects, helping the body cope with the stress and fatigue that may occur during the weight loss process.

[0032] Ginger extract is used to neutralize the side effects of gourd. Gingerol and shogaol in ginger extract have anti-inflammatory and antispasmodic effects, which can relieve gastrointestinal spasms and discomfort, reduce the symptoms of indigestion, and reduce the burden on the digestive system caused by the fiber components in gourd. The antioxidants and anti-inflammatory components in ginger extract can help neutralize the free radical damage caused by gourd intake, reduce inflammatory reactions, and inhibit the stimulation of gastric acid on the stomach wall.

[0033] Green tea extract is used to lower blood lipids, promote metabolism, remove excess oil, refresh the mind and fight fatigue;

[0034] Cactus extract is rich in vitamin C and antioxidants that protect the skin from free radical damage while promoting collagen synthesis, slowing down the skin aging process and keeping the skin firm and smooth.

[0035] The fat-reducing composition containing plant extract ingredients is prepared by the above-mentioned preparation method.

[0036] Beneficial effects of the present invention:

[0037] The present invention discloses a fat-reducing composition containing plant extract ingredients and a preparation method thereof. By optimizing the preparation process, a compound plant extract with fat-reducing effect is added, and okra extract, mountain mushroom extract, garcinia extract, bitter melon extract, gourd extract, licorice extract, ginger extract, green tea extract, and cactus extract are creatively compounded in an appropriate mass ratio to ensure that the various extracts can play a synergistic role and jointly promote human health. Through scientific proportioning, the effective ingredients in each extract can complement each other to achieve the best fat-reducing effect. By utilizing the synergistic effect between okra extract, mountain mushroom extract, garcinia extract and bitter melon extract, the cholesterol and triglyceride levels in the blood can be effectively reduced. These extracts work together to help reduce the accumulation of fat in the body, thereby increasing the body's basal metabolic rate. This increase in metabolic rate promotes the oxidative decomposition of fat, thereby increasing satiety and helping to regulate blood sugar levels. In addition, these extracts can also improve the balance of intestinal flora, thereby playing a fat-reducing role. The synergistic effect of gourd extract and cactus extract can maintain the healthy state of muscles and connective tissues, and effectively alleviate the problems of loose skin and wrinkles that may occur during fat loss. Licorice extract is specially added to regulate the side effects of okra extract, mountain mushroom extract, garcinia extract, bitter melon extract, etc. during weight loss. Licorice extract helps to reduce blood sugar fluctuations, enhance immune function, regulate water balance in the body, and has an anti-stress effect, thereby helping the body cope with stress and fatigue that may occur during weight loss. In order to neutralize the side effects of gourd, ginger extract is added. Finally, green tea extract is specially added to lower blood lipids, promote metabolism, remove excess oil, and have a refreshing and anti-fatigue effect. Through the combined effects of these natural extracts, the fat loss process can be more comprehensively supported while ensuring the health and balance of the body. DETAILED DESCRIPTION

[0038] In order to further illustrate the technical means and effects adopted by the present invention to achieve the predetermined invention purpose, the specific implementation methods, structures, features and effects of the present invention are described in detail below in combination with the embodiments.

[0039] Example 1

[0040] A method for preparing a fat-reducing composition containing plant extract ingredients, comprising the following steps:

[0041] S1. Mix starch, disodium hydrogen phosphate, citric acid and deionized water, stir at 50°C for 10 min, add α-amylase, continue stirring for 30 min, adjust the pH to 6, centrifuge, dry the solid phase, grind, and sieve with an 80-mesh sieve to obtain material A; the mass ratio of starch, disodium hydrogen phosphate, citric acid, deionized water and α-amylase is 20:0.56:0.35:60:0.06;

[0042] The starch is obtained by processing commercially available early indica brown rice through conventional processes in the art;

[0043] S2, taking the material A, sodium alginate, Dendrobium officinale extract, and deionized water, mixing and stirring for 10 hours to obtain material B; the mass ratio of the material A, sodium alginate, Dendrobium officinale extract, and deionized water is 6:1:0.1:50;

[0044] S3, take pig liver powder, cuttlebone powder, gluconolactone, sucrose fatty acid ester, and deionized water, mix, stir at 70 ° C for 20 minutes, cool to 45 ° C, add the material B, ultrasonically disperse for 2 minutes, heat to 85 ° C, stir for 1 minute, add the plant extract, homogenize at a speed of 3000 r / min for 2 minutes, and spray dry to obtain the fat-reducing composition;

[0045] The mass ratio of the pig liver powder, the cuttlebone powder, the gluconolactone, the sucrose fatty acid ester, the deionized water, the material B, and the plant extract is 1:1:0.05:0.05:200:10:30;

[0046] The spray drying is a well-known process in powder manufacturing and can be accomplished in any manner known in the art. This can be done by spraying the liquid material onto the top of a spray dryer, preferably with a high pressure swirl nozzle. The atomization pressure is 70 bar, with the temperature of the introduced hot air being in the range of 80° C. Suitable spray dryers and spray drying conditions are well known to those skilled in the art;

[0047] The cuttlebone powder is obtained by washing, drying and grinding the cuttlebone of squid;

[0048] The preparation method of the plant extract comprises the following steps:

[0049] A1. Wash fresh okra, put it into an extraction tank, add 10 times the amount of distilled water and boil for extraction three times, combine the extracts, concentrate and dry until the mass proportion of distilled water in the extract is less than 8%, spray dry, crush, and pass through a 100-mesh sieve to obtain an okra extract; the atomization pressure of the spray drying is 100 bar, and the temperature of the spray drying is 120° C.;

[0050] A2, washing fresh yam, peeling, pressing the pulp, filtering, and extracting the juice to obtain yam extract;

[0051] A3, washing fresh garcinia cambogia, peeling, pressing the pulp, filtering, and extracting the juice to obtain garcinia cambogia extract;

[0052] A4, washing and peeling fresh bitter melon, pressing the pulp, filtering, and extracting the juice to obtain bitter melon extract;

[0053] A5. Wash and slice fresh gourd, immerse in 5 times the amount of distilled water and heat to boiling, continue to cook for 80 min, filter, take the liquid phase, and obtain gourd extract;

[0054] A6, taking the okra extract, the mountain mushroom extract, the garcinia cambogia extract, the bitter melon extract, the gourd extract, the licorice extract, the ginger extract, the green tea extract, the cactus extract, and deionized water, mixing them, and ultrasonically dispersing them for 20 minutes to obtain the plant extract;

[0055] The mass ratio of the okra extract, the mountain mushroom extract, the garcinia cambogia extract, the bitter melon extract, the gourd extract, the licorice extract, the ginger extract, the green tea extract, the cactus extract and the deionized water is 15:20:8:5:2:0.6:0.1:1:1:50.

[0056] Example 2

[0057] A method for preparing a fat-reducing composition containing plant extract ingredients, comprising the following steps:

[0058] S1. Mix starch, disodium hydrogen phosphate, citric acid and deionized water, stir at 50°C for 15 min, add α-amylase, continue stirring for 35 min, adjust the pH to 6.5, centrifuge, dry the solid phase, grind, and sieve with a 90-mesh sieve to obtain material A; the mass ratio of starch, disodium hydrogen phosphate, citric acid, deionized water and α-amylase is 22:0.57:0.37:70:0.07;

[0059] The starch is obtained by processing commercially available early indica brown rice through conventional processes in the art;

[0060] S2, taking the material A, sodium alginate, Dendrobium officinale extract, and deionized water, mixing and stirring for 11 hours to obtain material B; the mass ratio of the material A, sodium alginate, Dendrobium officinale extract, and deionized water is 7:1.2:0.15:50;

[0061] S3, take pig liver powder, cuttlebone powder, gluconolactone, sucrose fatty acid ester, deionized water, mix, stir at 70 ° C for 25 minutes, cool to 50 ° C, add the material B, ultrasonically disperse for 2.5 minutes, heat to 90 ° C, stir for 1.5 minutes, add the plant extract, homogenize at a speed of 3500 r / min for 2.5 minutes, spray dry, and obtain the fat-reducing composition;

[0062] The mass ratio of the pig liver powder, the cuttlebone powder, the gluconolactone, the sucrose fatty acid ester, the deionized water, the material B, and the plant extract is 1.5:1.5:0.05:0.05:200:11:35;

[0063] The spray drying is a well-known process in powder manufacturing and it can be accomplished in any manner known in the art. This can be done by spraying the liquid material onto the top of a spray dryer, preferably with a high pressure swirl nozzle. The atomization pressure is 80 bar, with the temperature of the introduced hot air being in the range of 95°C. Suitable spray dryers and spray drying conditions are well known to those skilled in the art;

[0064] The cuttlebone powder is obtained by washing, drying and grinding the cuttlebone of squid;

[0065] The preparation method of the plant extract comprises the following steps:

[0066] A1. Wash fresh okra, put it into an extraction tank, add 10 times the amount of distilled water and boil for extraction three times, combine the extracts, concentrate and dry until the mass proportion of distilled water in the extract is less than 8%, spray dry, crush, and pass through a 100-mesh sieve to obtain an okra extract; the atomization pressure of the spray drying is 100 bar, and the temperature of the spray drying is 130° C.;

[0067] A2, washing fresh yam, peeling, pressing the pulp, filtering, and extracting the juice to obtain yam extract;

[0068] A3, washing fresh garcinia cambogia, peeling, pressing the pulp, filtering, and extracting the juice to obtain garcinia cambogia extract;

[0069] A4, washing and peeling fresh bitter melon, pressing the pulp, filtering, and extracting the juice to obtain bitter melon extract;

[0070] A5. Wash and slice fresh gourd seeds, immerse in 5 times the amount of distilled water and heat to boiling, continue to cook for 90 min, filter, and take the liquid phase to obtain gourd seed extract;

[0071] A6, taking the okra extract, the mountain mushroom extract, the garcinia cambogia extract, the bitter melon extract, the gourd extract, the licorice extract, the ginger extract, the green tea extract, the cactus extract, and deionized water, mixing them, and ultrasonically dispersing them for 25 minutes to obtain the plant extract;

[0072] The mass ratio of the okra extract, the mountain mushroom extract, the garcinia cambogia extract, the bitter melon extract, the gourd extract, the licorice extract, the ginger extract, the green tea extract, the cactus extract and the deionized water is 19:25:9:6:2.5:0.7:0.2:1.5:1.5:50.

[0073] Example 3

[0074] A method for preparing a fat-reducing composition containing plant extract ingredients, comprising the following steps:

[0075] S1. Mix starch, disodium hydrogen phosphate, citric acid and deionized water, stir at 50°C for 20 min, add α-amylase, continue stirring for 40 min, adjust the pH to 7, centrifuge, dry the solid phase, grind, and sieve with a 100-mesh sieve to obtain material A; the mass ratio of starch, disodium hydrogen phosphate, citric acid, deionized water and α-amylase is 24:0.58:0.38:80:0.08;

[0076] The starch is obtained by processing commercially available early indica brown rice through conventional processes in the art;

[0077] S2, taking the material A, sodium alginate, Dendrobium officinale extract, and deionized water, mixing and stirring for 12 hours to obtain material B; the mass ratio of the material A, sodium alginate, Dendrobium officinale extract, and deionized water is 8:1.5:0.2:50;

[0078] S3, take pig liver powder, cuttlebone powder, gluconolactone, sucrose fatty acid ester, deionized water, mix, stir at 70 ° C for 30 minutes, cool to 55 ° C, add the material B, ultrasonically disperse for 3 minutes, heat to 95 ° C, stir for 2 minutes, add the plant extract, homogenize at a speed of 4000 r / min for 3 minutes, spray dry, and obtain the fat-reducing composition;

[0079] The mass ratio of the pig liver powder, the cuttlebone powder, the gluconolactone, the sucrose fatty acid ester, the deionized water, the material B, and the plant extract is 2:2:0.05:0.05:200:12:40;

[0080] The spray drying is a well-known process in powder manufacturing and can be accomplished in any manner known in the art. This can be done by spraying the liquid material onto the top of a spray dryer, preferably with a high pressure swirl nozzle. The atomization pressure is 90 bar, with the temperature of the introduced hot air being in the range of 110° C. Suitable spray dryers and spray drying conditions are well known to those skilled in the art;

[0081] The cuttlebone powder is obtained by washing, drying and grinding the cuttlebone of squid;

[0082] The preparation method of the plant extract comprises the following steps:

[0083] A1. Wash fresh okra, put it into an extraction tank, add 10 times the amount of distilled water and boil for extraction three times, combine the extracts, concentrate and dry until the mass proportion of distilled water in the extract is less than 8%, spray dry, crush, and pass through a 100-mesh sieve to obtain an okra extract; the atomization pressure of the spray drying is 100 bar, and the temperature of the spray drying is 140° C.;

[0084] A2, washing fresh yam, peeling, pressing the pulp, filtering, and extracting the juice to obtain yam extract;

[0085] A3, washing fresh garcinia cambogia, peeling, pressing the pulp, filtering, and extracting the juice to obtain garcinia cambogia extract;

[0086] A4, washing and peeling fresh bitter melon, pressing the pulp, filtering, and extracting the juice to obtain bitter melon extract;

[0087] A5. Wash and slice fresh gourd, immerse in 5 times the amount of distilled water and heat to boiling, continue to cook for 100 min, filter, take the liquid phase, and obtain gourd extract;

[0088] A6, taking the okra extract, the mountain mushroom extract, the garcinia cambogia extract, the bitter melon extract, the gourd extract, the licorice extract, the ginger extract, the green tea extract, the cactus extract, and deionized water, mixing them, and ultrasonically dispersing them for 30 minutes to obtain the plant extract;

[0089] The mass ratio of the okra extract, the mountain mushroom extract, the garcinia cambogia extract, the bitter melon extract, the gourd extract, the licorice extract, the ginger extract, the green tea extract, the cactus extract and the deionized water is 22:30:10:7:3:0.8:0.3:2:2:50.

[0090] Comparative Example 1

[0091] The difference from Example 2 is that the method for preparing the fat-reducing composition containing plant extract ingredients comprises the following steps:

[0092] S1. Mix starch, sodium alginate, Dendrobium officinale extract and deionized water, and stir for 11 hours to obtain material B; the mass ratio of starch, sodium alginate, Dendrobium officinale extract and deionized water is 7:1.2:0.15:50; the starch is commercially available early indica brown rice processed by conventional processes in the art;

[0093] S2, take pig liver powder, sea cucumber powder, gluconolactone, sucrose fatty acid ester, deionized water, mix, stir at 70 ℃ for 25min, cool to 50 ℃, add material B, ultrasonically disperse for 2.5min, heat to 90 ℃, stir for 1.5min, add plant extract, homogenize at a speed of 3500r / min for 2.5min, spray dry, and obtain the fat-reducing composition; the mass ratio of the pig liver powder, sea cucumber powder, gluconolactone, sucrose fatty acid ester, deionized water, material B, and plant extract is 1.5:1.5:0.05:0.05:200:11:35; the spray drying is a well-known process in powder manufacturing, and it can be done in any way known in the art. This can be done by spraying the liquid material onto the top of the spray dryer, preferably with a high-pressure swirl nozzle. The atomization pressure is 80bar, and the temperature of the introduced hot air is in the range of 95℃. Suitable spray dryers and spray drying conditions are well known to those skilled in the art; the cuttlebone powder is obtained by washing, drying and grinding cuttlebone of squid.

[0094] Comparative Example 2

[0095] The difference from Example 2 is that the method for preparing the fat-reducing composition containing plant extract ingredients comprises the following steps:

[0096] S1. Mix starch, disodium hydrogen phosphate, citric acid and deionized water, stir at 50°C for 15 min, add α-amylase, continue stirring for 35 min, adjust the pH to 6.5, centrifuge, dry the solid phase, grind, and sieve with a 90-mesh sieve to obtain material A; the mass ratio of starch, disodium hydrogen phosphate, citric acid, deionized water and α-amylase is 22:0.57:0.37:70:0.07;

[0097] The starch is obtained by processing commercially available early indica brown rice through conventional processes in the art;

[0098] S2, taking the material A, sodium alginate, Dendrobium officinale extract, and deionized water, mixing and stirring for 11 hours to obtain material B; the mass ratio of the material A, sodium alginate, Dendrobium officinale extract, and deionized water is 7:1.2:0.15:50;

[0099] S3, taking the material B, heating it to 90°C, stirring for 1.5min, adding the plant extract, homogenizing at a speed of 3500r / min for 2.5min, and spray drying to obtain the fat-reducing composition;

[0100] The mass ratio of material B to plant extract is 11:35;

[0101] The spray drying is a well-known process in powder manufacturing and can be accomplished in any manner known in the art. This can be done by spraying the liquid material onto the top of a spray dryer, preferably with a high pressure swirl nozzle. The atomization pressure is 80 bar, with the temperature of the introduced hot air being in the range of 95°C. Suitable spray dryers and spray drying conditions are well known to those skilled in the art; the cuttlebone powder is obtained by washing, drying and grinding the cuttlebone of a squid.

[0102] Comparative Example 3

[0103] The difference from Example 2 is that the Dendrobium officinale extract is not added in step S2.

[0104] Comparative Example 4

[0105] The difference from Example 2 is that the mass ratio of the okra extract, mountain mushroom extract, garcinia cambogia extract, bitter melon extract, gourd extract, licorice extract, ginger extract, green tea extract, cactus extract and deionized water in the plant extract is 0:25:28:6:2.5:0.7:0.2:1.5:1.5:50.

[0106] Comparative Example 5

[0107] The difference from Example 2 is that the mass ratio of the okra extract, mountain mushroom extract, garcinia cambogia extract, bitter melon extract, gourd extract, licorice extract, ginger extract, green tea extract, cactus extract and deionized water in the plant extract is 44:0:9:6:2.5:0.7:0.2:1.5:1.5:50.

[0108] Comparative Example 6

[0109] The difference from Example 2 is that the mass ratio of the okra extract, mountain mushroom extract, garcinia cambogia extract, bitter melon extract, gourd extract, licorice extract, ginger extract, green tea extract, cactus extract and deionized water in the plant extract is 19:25:0:15:2.5:0.7:0.2:1.5:1.5:50.

[0110] Comparative Example 7

[0111] The difference from Example 2 is that the mass ratio of the okra extract, mountain mushroom extract, garcinia cambogia extract, bitter melon extract, gourd extract, licorice extract, ginger extract, green tea extract, cactus extract and deionized water in the plant extract is 19:25:15:0:2.5:0.7:0.2:1.5:1.5:50.

[0112] Comparative Example 8

[0113] The difference from Example 2 is that the mass ratio of the okra extract, mountain mushroom extract, garcinia cambogia extract, bitter melon extract, gourd extract, licorice extract, ginger extract, green tea extract, cactus extract and deionized water in the plant extract is 19:25:9:8.5:0:0.7:0.2:1.5:1.5:50.

[0114] Comparative Example 9

[0115] The difference from Example 2 is that the mass ratio of the okra extract, mountain mushroom extract, garcinia cambogia extract, bitter melon extract, gourd extract, licorice extract, ginger extract, green tea extract, cactus extract and deionized water in the plant extract is 19:25:9:6.7:2.5:0:0.2:1.5:1.5:50.

[0116] Comparative Example 10

[0117] The difference from Example 2 is that the mass ratio of the okra extract, mountain mushroom extract, garcinia cambogia extract, bitter melon extract, gourd extract, licorice extract, ginger extract, green tea extract, cactus extract and deionized water in the plant extract is 19:25:9:6:2.5:0.9:0:1.5:1.5:50.

[0118] Comparative Example 11

[0119] The difference from Example 2 is that the mass ratio of the okra extract, mountain mushroom extract, garcinia cambogia extract, bitter melon extract, gourd extract, licorice extract, ginger extract, green tea extract, cactus extract and deionized water in the plant extract is 19:25:9:6:2.5:0.7:0.2:0:3:50.

[0120] Comparative Example 12

[0121] The difference from Example 2 is that the mass ratio of the okra extract, mountain mushroom extract, garcinia cambogia extract, bitter melon extract, gourd extract, licorice extract, ginger extract, green tea extract, cactus extract and deionized water in the plant extract is 19:25:9:6:2.5:0.7:0.2:3:0:50.

[0122] Performance Testing

[0123] Healthy C57BL / 6J mice aged 4 weeks (average weight 15-16g) were purchased, and after one week of adaptive feeding, they were fed with a high-fat diet for 6 weeks to obtain obese model mice, which were randomly divided into a control group and an experimental group (including Example Groups 1-3 and Comparative Example Groups 1-12), with 10 mice in each group. The control group continued to be fed with a high-fat diet, the experimental group was fed with an equal amount of high-fat diet and fed with the fat-reducing composition prepared in Example 1-3 and Comparative Example 1-12 (10g / kg·d) every day, and the control group was gavaged with the same amount of normal saline. After 5 consecutive weeks, blood was collected from the carotid artery and the heart, and the carotid blood was tested for superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activity (using the SODWST-1 method kit and the GSH-Px activity assay kit purchased from Nanjing Jiancheng Bioengineering Institute, and tested according to the kit requirements), and the blood at the heart was tested for TG, TC, HDL-C and LDL-C levels in mouse serum using a fully automatic biochemical analyzer. The weight changes of mice before and after the experiment (measured as the average weight of each group) and the abdominal skin conditions of mice were recorded. There was no statistical difference in the values ​​(P < 0.05), so the average values ​​were taken. See Tables 1-3 for details.

[0124] Table 1 Detection values ​​of blood lipid levels in mice

[0125]

[0126]

[0127] Table 2 SOD and GSH-Px activity test results

[0128]

[0129]

[0130] Table 3 Average weight of mice

[0131]

[0132]

[0133] It can be seen from Tables 1-3 that the fat-reducing compositions prepared in Examples 1-3 of the present application have good fat-reducing effects; the present application reduces the loss of plant extracts during the spray drying process by preparing modified starch and combining it with Dendrobium officinale extract, pig liver powder, and cuttlebone powder; and achieves a good fat-reducing effect through the synergistic effect between okra extract, mountain mushroom extract, garcinia fruit extract, bitter melon extract, gourd extract, licorice extract, ginger extract, green tea extract, and cactus extract.

[0134] The above description is only a preferred embodiment of the present invention and does not limit the present invention in any form. Although the present invention has been disclosed as a preferred embodiment as above, it is not used to limit the present invention. Any technical personnel in this field can make some changes or modify the technical contents disclosed above into equivalent embodiments without departing from the scope of the technical solution of the present invention. However, any brief modifications, equivalent changes and modifications made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention are still within the scope of the technical solution of the present invention.

Claims

1. A method for preparing a fat-reducing composition containing plant extract ingredients, characterized in that: The following steps are involved: S1. Mix starch, disodium hydrogen phosphate, citric acid and deionized water, heat and stir, add α-amylase, continue stirring, adjust the pH to 6-7, centrifuge, dry the solid phase, grind and sieve to obtain material A; S2, mixing the material A, sodium alginate, Dendrobium officinale extract and deionized water, stirring to obtain material B; S3, take pig liver powder, cuttlebone powder, gluconolactone, sucrose fatty acid ester, and deionized water, mix, heat and stir, cool to 45-55° C., add the material B, ultrasonically disperse, heat to 85-95° C., stir for 1-2 min, add the plant extract, homogenize, and spray dry to obtain the fat-reducing composition; In step S1, the mass ratio of starch, disodium hydrogen phosphate, citric acid, deionized water, and α-amylase is 20-24: 0.56-0.58: 0.35-0.38: 60-80: 0.06-0.08; In step S2, the mass ratio of material A, sodium alginate, Dendrobium officinale extract, and deionized water is 6-8:1-1.5:0.1-0.2:50; In step S3, the mass ratio of the pig liver powder, the cuttlebone powder, the gluconolactone, the sucrose fatty acid ester, the deionized water, the material B, and the plant extract is 1-2: 1-2: 0.05: 0.05: 200: 10-12: 30-40; The preparation method of the plant extract comprises the following steps: A1. Wash fresh okra, put it into an extraction tank, add 10 times the amount of distilled water and boil for extraction three times, combine the extracts, concentrate and dry until the mass proportion of distilled water in the extract is less than 8%, spray dry, crush, and sieve to obtain okra extract; A2, washing fresh yam, peeling, pressing the pulp, filtering, and extracting the juice to obtain yam extract; A3, washing fresh garcinia cambogia, peeling, pressing the pulp, filtering, and obtaining the juice to obtain garcinia cambogia extract; A4, washing and peeling fresh bitter melon, pressing the pulp, filtering, and extracting the juice to obtain bitter melon extract; A5. Wash and slice fresh gourd, immerse in 5 times the amount of distilled water and heat to boiling, continue to cook, filter, take the liquid phase, and obtain gourd extract; A6, taking the okra extract, the mountain mushroom extract, the garcinia cambogia extract, the bitter melon extract, the gourd extract, the licorice extract, the ginger extract, the green tea extract, the cactus extract, and deionized water, mixing them, and ultrasonically dispersing them to obtain the plant extract; In step A6, the mass ratio of okra extract, mountain mushroom extract, garcinia cambogia extract, bitter melon extract, gourd extract, licorice extract, ginger extract, green tea extract, cactus extract, and deionized water is 15-22:20-30:8-10:5-7:2-3:0.6-0.8:0.1-0.3:1-2:1-2:50; In step S3, the atomization pressure of the spray drying is 70-90 bar, and the temperature of the spray drying is 80-110° C.; In step S3, the homogenization refers to homogenization at a speed of 3000-4000 r / min for 2-3 min; In step A1, the atomization pressure of the spray drying is 100 bar, and the temperature of the spray drying is 120-140°C.

2. A fat-reducing composition containing plant extract ingredients obtained by the preparation method as claimed in claim 1.

Citation Information

Patent Citations

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