Blood sample status assessment method and system
By using spectral analysis technology in the blood sample status assessment, the problem of inaccurate samples evaluation and status judgment in existing technologies have been solved, and more efficient and accurate blood sample status assessment has been achieved.
Patent Information
- Application Number
- CN202411537735.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-31
- Publication Date
- 2025-01-28
- Estimated Expiration
- 2044-10-31
AI Technical Summary
The prior art has problems of inaccuracy and inefficiency in blood sample size evaluation and status judgment, which affects the accuracy and reliability of the test results.
The blood sample state assessment method is adopted to transmit a specific spectrum through the wavelength transmitter to the blood sample to obtain the absorbance data, and the state evaluation is performed according to the preset absorbance threshold interval to reduce human error and improve the detection efficiency.
Through spectral analysis, accurately assess the state of blood samples, reduce interference of subjective judgment, improve detection efficiency and accuracy, timely discover abnormal samples, and support subsequent treatment.
Smart Images

Figure CN119044097B_ABST
Abstract
Description
Technical Field
[0001] The embodiments of the present application relate to the field of medical detection technology, and in particular, to a method and system for evaluating the status of a blood sample. Background Art
[0002] In the current third-party medical testing field, in order to ensure the accuracy and reliability of the test results, the demand for samples submitted for testing is usually large, and there are strict requirements on the quality and status of the samples. Specifically: experiments usually require sufficient sample volume to ensure the repeatability and accuracy of the test results. If the sample volume submitted for testing is insufficient, the laboratory may not be able to complete the test, resulting in the need to return the order, which not only wastes valuable testing resources, but may also delay the patient's diagnosis and treatment; the state of the sample is crucial to the test results. For example, if the sample is hemolyzed (red blood cells rupture and hemoglobin is released into the plasma) or jaundice (increased bilirubin levels in the blood), these abnormal conditions may affect the accuracy of the test results. Therefore, when the sample has these conditions, technicians are required to take out these samples separately to further determine the degree to which they do not meet the standards.
[0003] Currently, many laboratories still rely on technicians to evaluate the effective sample volume and sample status through visual observation. This method is not only inefficient and prone to errors due to subjective judgment, but also significantly increases the time required for testing when processing a large number of samples, thus affecting the overall testing process and efficiency. Summary of the invention
[0004] One purpose of the embodiments of the present application is to provide a blood sample status assessment method and system to solve the technical problems of inaccuracy and low efficiency in sample quantity assessment and sample status judgment in existing detection methods.
[0005] In a first aspect, a blood sample state assessment method is provided, which is applied to a blood sample state assessment system, and the method comprises:
[0006] Obtaining a pre-treated blood sample to be tested;
[0007] Controlling the wavelength transmitter in the blood sample state evaluation system to transmit a first type of spectrum and a second type of spectrum to the blood sample to be detected, and obtaining a first target absorbance region, a second target absorbance region and a third target absorbance region of the blood sample to be detected under the first type of spectrum;
[0008] According to the first target absorbance region, the second target absorbance region and the third target absorbance region, a first target absorbance mean corresponding to the first target absorbance region, a second target absorbance mean corresponding to the second target absorbance region and a third target absorbance mean corresponding to the third target absorbance region are obtained;
[0009] Determining the blood sample to be tested as a target test blood sample according to the first target absorbance mean value and / or the third target absorbance mean value;
[0010] The state of the target detection blood sample is evaluated according to the preset absorbance threshold interval, the second target absorbance mean value and the third target absorbance mean value to obtain an evaluation result of the target detection blood sample.
[0011] In a second aspect, a blood sample status assessment system is provided, the system comprising:
[0012] An acquisition unit, used for acquiring a pre-treated blood sample to be tested;
[0013] a determination unit, configured to control the wavelength transmitter in the blood sample state evaluation system to transmit a first type of spectrum and a second type of spectrum to the blood sample to be detected, so as to obtain a first target absorbance region, a second target absorbance region and a third target absorbance region of the blood sample to be detected under the first type of spectrum;
[0014] The determining unit is further configured to obtain, according to the first target absorbance region, the second target absorbance region and the third target absorbance region, a first target absorbance mean corresponding to the first target absorbance region, a second target absorbance mean corresponding to the second target absorbance region and a third target absorbance mean corresponding to the third target absorbance region;
[0015] The determining unit is further used to determine that the blood sample to be tested is a target test blood sample according to the first target absorbance mean value and / or the third target absorbance mean value;
[0016] An evaluation unit is used to perform a status evaluation on the target detection blood sample according to a preset absorbance threshold interval, the second target absorbance mean value and the third target absorbance mean value to obtain an evaluation result of the target detection blood sample.
[0017] In a third aspect, an embodiment of the present invention provides a computer device, including:
[0018] at least one processor; and,
[0019] a memory communicatively connected to the at least one processor; wherein,
[0020] The memory stores instructions that can be executed by the at least one processor, and the instructions are executed by the at least one processor to enable the at least one processor to perform the method according to the first aspect.
[0021] In a fourth aspect, a computer-readable storage medium is provided, wherein the computer-readable storage medium stores a computer program, wherein the computer program includes program instructions, and when the program instructions are executed by a processor, the processor executes the method as described in the first aspect.
[0022] In the scheme implemented by the above-mentioned blood sample state evaluation method and system, first, a pre-processed blood sample to be detected is obtained. Secondly, a wavelength transmitter in the blood sample state evaluation system is controlled to emit a first type of spectrum and a second type of spectrum to the blood sample to be detected, so as to obtain a first target absorbance region, a second target absorbance region and a third target absorbance region of the blood sample to be detected under the first type of spectrum. Then, according to the first target absorbance region, the second target absorbance region and the third target absorbance region, a first target absorbance mean corresponding to the first target absorbance region, a second target absorbance mean corresponding to the second target absorbance region and a third target absorbance mean corresponding to the third target absorbance region are obtained. Finally, according to the first target absorbance mean and / or the third target absorbance mean, it is determined that the blood sample to be detected is a target detection blood sample. The state of the target detection blood sample is evaluated according to a preset absorbance threshold interval, the second target absorbance mean and the third target absorbance mean, so as to obtain an evaluation result of the target detection blood sample. By using specific spectral analysis, the method can more accurately evaluate the state of the blood sample. Compared with the traditional subjective observation method, spectral analysis reduces human errors and can provide more objective and accurate data; further calculation of the first target absorbance mean, the second target absorbance mean and the third target absorbance mean makes the sample state evaluation more quantitative and reduces the interference of subjective judgment; further by determining the target detection blood sample, it is possible to quickly screen out samples that meet the requirements, improve detection efficiency, and reduce unnecessary tests; and in combination with the preset absorbance threshold range, the sample state is evaluated, sample abnormalities can be discovered in time, and a basis for subsequent processing can be provided. Therefore, the method reduces the time and errors of manual operation through automated spectral detection and analysis, and significantly improves efficiency and accuracy. BRIEF DESCRIPTION OF THE DRAWINGS
[0023] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the description of the embodiments of the present application will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative labor.
[0024] Figure 1 is a schematic diagram of a scenario of a method for evaluating a blood sample state in one embodiment of the present invention;
[0025] Figure 2 is a flow chart of a method for evaluating a blood sample state in one embodiment of the present invention;
[0026] Figure 3 is a schematic diagram of the structure of a blood sample status evaluation system in one embodiment of the present invention;
[0027] Figure 4 It is a schematic diagram of the structure of a computer device in one embodiment of the present invention. DETAILED DESCRIPTION
[0028] In order to make the purpose, technical solutions and advantages of the present application more clearly understood, the present application is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not intended to limit the present application. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in the field without making creative work are within the scope of protection of the present application.
[0029] It should be noted that, if there is no conflict, the various features in the embodiments of the present application can be combined with each other, all within the scope of protection of the present application. In addition, although the functional module division is performed in the device schematic diagram and the logical order is shown in the flow chart, in some cases, the steps shown or described can be performed in a sequence different from the module division in the device or the flow chart. Furthermore, the words "first", "second", "third", etc. used in this application do not limit the data and execution order, but only distinguish the same items or similar items with basically the same functions and effects.
[0030] The present invention is described in detail below through specific embodiments.
[0031] The technical solution of the present application can be applied to a variety of medical detection scenarios.
[0032] In the blood sample status assessment method, applied to the blood sample status assessment system, see Figure 1 , Figure 1 A schematic diagram of a liquid sample state evaluation method provided in an embodiment of the present application, in Figure 1The whole process of the method for evaluating the status of a blood sample is described in which the centrifuged sample is placed in a sample rack and the wavelength emitter is controlled to emit a spectrum to the sample from top to bottom. Note that the centrifuged sample is plasma, white blood cells, platelets, and red blood cells from top to bottom. The sample here is only an example and is not the only representation.
[0033] The blood sample status evaluation system 10 includes a wavelength transmitter 20, a sample rack 30, and a data processing module. The blood sample status evaluation system 10 is an integrated detection platform designed to quickly and accurately evaluate the status of blood samples. The system realizes automated detection and analysis of blood samples by combining hardware and software.
[0034] The sample rack 30 is used to place and fix the blood sample to be tested. The sample rack 30 is usually designed to accommodate multiple sample tubes or microplates to ensure that the sample remains stable during the test and avoids tilting or movement, thereby ensuring the accuracy of the test results. During the test, the sample rack 30 can be automatically or manually loaded and unloaded by the system to achieve high-throughput processing of samples.
[0035] The wavelength emitter 20 is composed of two wavelength emitters, which can emit excitation light of 278nm and 415nm wavelengths respectively. These two wavelengths are selected to detect the absorbance of different components in the blood sample, which can provide rich spectral information for easy analysis. The wavelength emitter 20 is designed to run from top to bottom along a preset track, and the emitter operates at different positions above the sample rack 30, so that multiple samples or different parts of the same sample can be detected continuously or in parallel.
[0036] The data processing module is used to receive the spectral data collected by the wavelength transmitter 20, and process and analyze it. The module can perform a variety of data processing tasks, including but not limited to the calculation of absorbance, determination of absorbance mean, evaluation of sample status, and output of results. The data processing module usually contains a dedicated software algorithm that can interpret the data according to preset standards and parameters to automatically determine the status of the sample (such as whether it is hemolyzed, whether it is icteric, etc.). The data processing module may also provide a user interface that allows the operator to monitor the detection process, view the results, and generate reports.
[0037] Therefore, the blood sample status assessment system can provide efficient, accurate and reliable blood sample testing services, and is suitable for clinical laboratories, research institutions and other occasions where blood testing is required.
[0038] In view of this, the present application proposes a blood sample status assessment method to solve the above problems, which is described in detail below.
[0039] See also Figure 2, Figure 2 A flow chart of a method for evaluating the state of a blood sample provided by an embodiment of the present invention, the method comprising the following steps:
[0040] S10, obtaining a pre-treated blood sample to be tested.
[0041] The above-mentioned pretreatment is to separate the required components from the original blood sample to be tested so as to carry out subsequent specific tests. The pretreatment can remove unnecessary components, reduce interference, and improve the accuracy and repeatability of the test.
[0042] Optionally, the pretreatment may be a centrifugal treatment, which relies on the centrifugal force generated by high-speed rotation to separate blood components of different densities into layers according to gravity, thereby quickly and effectively separating blood cells and plasma or serum, making it easier to detect and analyze specific components.
[0043] For example, the blood sample to be tested is placed in a blood collection tube containing an anticoagulant and is fully centrifuged by a centrifuge. After centrifugation, the blood sample to be tested will be divided into three layers: from top to bottom, the plasma layer, the white blood cell and platelet layer, and the red blood cell layer.
[0044] For example, the blood sample to be tested is placed in a blood collection tube containing separation gel and coagulant, and is fully centrifuged in a centrifuge. After centrifugation, the blood sample to be tested will be divided into three layers: serum, separation gel, and blood cells from top to bottom.
[0045] The choice of centrifugation method depends on the subsequent testing requirements. If the test target is a specific component in the serum, use a tube with a coagulant and a separation gel for centrifugation. If the target is plasma or blood cells, use a blood collection tube containing an anticoagulant.
[0046] Among them, the centrifugation speed, time and materials used (such as the type of blood collection tube) need to be selected and adjusted according to the specific experimental requirements and standard operating procedures to ensure that the samples can be processed correctly.
[0047] It can be seen that the centrifugal pretreatment of the blood sample to be tested in this embodiment can obtain blood components suitable for spectral analysis or other biochemical tests, laying a foundation for accurately evaluating the status of the blood sample.
[0048] S20, controlling the wavelength transmitter in the blood sample status evaluation system to transmit a first type of spectrum and a second type of spectrum to the blood sample to be detected, to obtain a first target absorbance region, a second target absorbance region and a third target absorbance region of the blood sample to be detected under the first type of spectrum.
[0049] Among them, by emitting spectra of specific wavelengths, the absorbance of blood samples at different wavelengths can be measured to evaluate the state of the blood samples. The absorbance can reflect the concentration and properties of different components in the sample.
[0050] The first type of spectrum may have a wavelength of 415 nm, and the second type of spectrum may have a wavelength of 278 nm.
[0051] Among them, in the first type of spectrum at a wavelength of 415nm, three absorbance regions, absorbance 1, absorbance 2, and absorbance 3, can be obtained. When the absorbance point position calculates the intercept k>0 for n consecutive times, it is regarded as the beginning of absorbance region 1, and the scanning interval is recorded as Z1. When the absorbance point position calculates the intercept k<0 for n consecutive times, it is regarded as the end of absorbance region 1, and the scanning interval is recorded as Z2. The absorbance 1 region is the serum or plasma region; continue scanning, and when the absorbance point position calculates the intercept k>0 for n consecutive times, it is regarded as the beginning of absorbance region 2. The scanning interval is recorded as Z3. When the absorbance point calculates the intercept k<0 for n consecutive times, it is regarded as the end of absorbance area 2. At this time, the scanning interval is recorded as Z4, and the absorbance 2 area is the white blood cell and platelet area; continue scanning, when the absorbance point calculates the intercept k>0 for n consecutive times, it is regarded as the beginning of absorbance area 3, and the scanning interval is recorded as Z5. When the absorbance point calculates the intercept k<0 for n consecutive times, it is regarded as the end of absorbance area 3. At this time, the scanning interval is recorded as Z6, and the absorbance 3 area is the red blood cell or blood cell area.
[0052] Similarly, in the second type of spectrum at a wavelength of 278nm, three absorbance regions, absorbance 4, absorbance 5, and absorbance 6, can be obtained. When the absorbance point position calculates the intercept k>0 for n consecutive times, it is regarded as the beginning of absorbance region 4, and the scanning interval is recorded as Z7. When the absorbance point position calculates the intercept k<0 for n consecutive times, it is regarded as the end of absorbance region 4, and the scanning interval is recorded as Z8. The absorbance region 4 is the serum or plasma region. Continue scanning. When the absorbance point position calculates the intercept k>0 for n consecutive times, it is regarded as the beginning of absorbance region 5, and the scanning interval is recorded as Z9. When the absorbance point position calculates the intercept k<0 for n consecutive times, it is regarded as the end of absorbance region 5, and the scanning interval is recorded as Z 10 , the absorbance 5 area is the white blood cell and platelet area; continue scanning, when the absorbance point position calculates the intercept k>0 for n consecutive times, it is regarded as the beginning of absorbance area 6, and the scanning interval is recorded as Z at this time 11 When the absorbance point is calculated for n consecutive times and the intercept k < 0, it is regarded as the end of absorbance region 6, and the scanning interval is recorded as Z. 12 , the absorbance 6 area is the red blood cell or blood cell area.
[0053] Among them, the first target absorbance region can be the absorbance 3 region under the first type of spectrum (415nm wavelength), that is, the red blood cell or blood cell region; the second target absorbance region can be the absorbance 1 region under the first type of spectrum, that is, the serum or plasma region.
[0054] The third target absorbance region is absorbance region 4 under the second type of spectrum (278 nm wavelength), that is, the serum or plasma region.
[0055] It can be seen that in this embodiment, by effectively controlling the emission spectrum of the wavelength emitter and analyzing the status of different components in the blood sample through the change of absorbance, not only the analysis ability of the blood sample is improved, but also the foundation is laid for subsequent data processing and evaluation, ensuring the scientificity and accuracy of the experiment.
[0056] In a possible example, the controlling of the wavelength transmitter in the blood sample state evaluation system to transmit the first type of spectrum and the second type of spectrum to the blood sample to be detected, and obtaining the first target absorbance region, the second target absorbance region, and the third target absorbance region of the blood sample to be detected under the first type of spectrum, includes: controlling the wavelength transmitter in the blood sample state evaluation system to transmit the first type of spectrum and the second type of spectrum to the blood sample to be detected at a preset absorbance point position frequency, and obtaining a first absorbance point position sequence corresponding to the first type of spectrum. a second absorbance point sequence corresponding to a first type of spectrum and a second absorbance point sequence corresponding to the second type of spectrum; in the first absorbance point sequence, absorbance region judgment is performed from top to bottom to obtain a first absorbance region, a second absorbance region and a third absorbance region; the third absorbance region is determined to be a first target absorbance region and the first absorbance region is determined to be a second target absorbance region; in the second absorbance point sequence, the absorbance region judgment is performed from top to bottom to obtain a fourth absorbance region, a fifth absorbance region and a sixth absorbance region; the fourth absorbance region is determined to be a third target absorbance region.
[0057] The preset absorbance point frequency means that when the spectrum is emitted, the wavelength transmitter scans the blood sample at a preset frequency. The preset absorbance point frequency determines the resolution of the scan, that is, the absorbance value is recorded every certain distance. The preset absorbance point frequency can be 1mm / time. Specifically, each measured light beam will advance 1mm along the sample, thereby continuously collecting absorbance data.
[0058] Among them, the first absorbance point sequence is that after emitting the first type of spectrum, the system records the data of each absorbance point to form a sequence; the first absorbance point sequence records the absorbance value of the blood sample to be tested at a wavelength of 415nm in order from top to bottom.
[0059] Among them, the second absorbance point sequence is that after emitting the second type of spectrum, the system records the data of each absorbance point to form a sequence; the second absorbance point sequence records the absorbance value of the blood sample to be tested at a wavelength of 278nm in order from top to bottom.
[0060] The division of absorbance regions is based on the change in absorbance of the blood sample to be tested at a specific wavelength. By judging the change in the intercept between two adjacent absorbance points, the absorption characteristics of different components in the sample can be effectively identified.
[0061] Specifically, the absorbance region is determined as a target absorbance region in which the intercept of two adjacent absorbance points in the first absorbance point sequence or the second absorbance point sequence is greater than 0 and is detected in continuous scanning until the intercept of two adjacent absorbance points is less than 0.
[0062] The intercept refers to the value of the intersection of the straight line formed by two adjacent absorbance points and the absorbance axis. The intercept reflects the trend of absorbance change from one point to the next.
[0063] Specifically, when the intercepts of two adjacent points are continuously greater than 0, it means that the light is absorbed by the sample and an absorbance area begins to form. At this time, the system records the starting point of the area; when the continuously appearing intercepts change from greater than 0 to less than 0, it indicates that the absorption of light ends, the end of the current absorbance area is determined, and the system records the end point of the area.
[0064] For example, the specific case is consistent with the process described in S20: at a wavelength of 415nm in the first spectrum, three absorbance regions, absorbance 1, absorbance 2, and absorbance 3, can be obtained by moving forward 1mm along the sample; at a wavelength of 278nm in the second spectrum, three absorbance regions, absorbance 4, absorbance 5, and absorbance 6 can be obtained by moving forward 1mm along the sample. The overall division of regional absorbance regions is consistent with the process described in S20.
[0065] Among them, the first absorbance area is such as the absorbance 1 area mentioned in S20, that is, the serum or plasma area; the second absorbance area is such as the absorbance 2 area mentioned in S20, that is, the white blood cell and platelet area; the third absorbance area is such as the absorbance 3 area mentioned in S20, that is, the red blood cell or blood cell area.
[0066] Further, in determining the third absorbance region as the first target absorbance region and determining the first absorbance region as the second target absorbance region, the specific description is the same as that described in S20.
[0067] Among them, the fourth absorbance region is such as the absorbance 4 region mentioned in S20, that is, the serum or plasma region; the fifth absorbance region is such as the absorbance 5 region mentioned in S20, that is, the white blood cell and platelet region; the sixth absorbance region is such as the absorbance 6 region mentioned in S20, that is, the red blood cell or blood cell region.
[0068] Further, in determining the fourth absorbance region as the third target absorbance region, the specific description is consistent with that described in S20.
[0069] It can be seen that the method of determining the division of absorbance regions by the change in the intercepts of adjacent absorbance points in this embodiment not only improves the accuracy of region determination, but also provides reliable data support for the subsequent analysis of blood sample components.
[0070] S30. According to the first target absorbance region, the second target absorbance region and the third target absorbance region, a first target absorbance mean corresponding to the first target absorbance region, a second target absorbance mean corresponding to the second target absorbance region and a third target absorbance mean corresponding to the third target absorbance region are obtained.
[0071] The absorbance mean refers to the average absorbance value calculated in the corresponding absorbance region, which can reflect the concentration or quantity of blood components in the region.
[0072] Among them, the first target absorbance mean can be obtained by averaging all absorbance values in the first target absorbance area, collecting all absorbance values in the first target absorbance area, adding these values, and then dividing them by the total number of values to obtain the mean; averaging all absorbance values in the second target absorbance area, the steps are the same as the first target absorbance mean; averaging all absorbance values in the third target absorbance area, the steps are the same as above.
[0073] In one possible example, according to the first target absorbance area, the second target absorbance area and the third target absorbance area, the first target absorbance mean corresponding to the first target absorbance area, the second target absorbance mean corresponding to the second target absorbance area and the third target absorbance mean corresponding to the third target absorbance area are obtained, including: obtaining a first time period corresponding to the first target absorbance area, a second time period corresponding to the second target absorbance area and a third time period corresponding to the third target absorbance area; according to the numerical value of each absorbance in the first target absorbance area and the first time period, obtaining the first target absorbance mean; according to the numerical value of each absorbance in the second target absorbance area and the second time period, obtaining the second target absorbance mean; according to the numerical value of each absorbance in the third target absorbance area and the third time period, obtaining the third target absorbance mean.
[0074] The first time period is the time period covered by the first target absorbance region; the second time period is the time period covered by the second target absorbance region; and the third time period is the time period covered by the third target absorbance region. The above time periods can be actual time or relative positions or steps in the scanning process.
[0075] Among them, as mentioned in S20, the first time period is Z5-Z6; the second time period is Z1-Z2; and the third time period is Z7-Z8.
[0076] For example, the first target absorbance region: from position 5mm to 10mm; the second target absorbance region: from position 15mm to 20mm; the third target absorbance region: from position 25mm to 30mm. The first target absorbance region: [0.5, 0.6, 0.55, 0.58, 0.53]; the second target absorbance region: [0.3, 0.32, 0.29, 0.31]; the third target absorbance region: [0.25, 0.26, 0.24, 0.27]. The mean absorbance of the first target = (0.5 + 0.6 + 0.55 + 0.58 +0.53) / 5 = 0.556; the mean absorbance of the second target = (0.3 + 0.32 + 0.29 + 0.31) / 4 = 0.305; the mean absorbance of the third target = (0.25 + 0.26 + 0.24 + 0.27) / 4 = 0.255.
[0077] It can be seen that in this embodiment, by calculating the mean absorbance, the average absorbance values of the blood sample in different areas can be provided, and these values can be further used to analyze the composition and state of the sample. For example, by comparing the mean absorbance values of different samples or the same sample under different conditions, the disease state can be diagnosed or monitored.
[0078] S40: Determine, according to the first target absorbance mean value and / or the third target absorbance mean value, that the blood sample to be tested is a target test blood sample.
[0079] Among them, the first target absorbance area can be the absorbance 3 area under the first type of spectrum (415nm wavelength), that is, the red blood cell or blood cell area, so the sample amount corresponding to the red blood cell or blood cell area determines whether the blood sample to be tested is the target test blood sample.
[0080] Among them, target detection blood samples refer to blood samples that meet specific conditions or standards, usually those containing sufficient amounts of red blood cells or blood cells.
[0081] In a possible example, determining that the blood sample to be tested is a target detection blood sample based on the first target absorbance mean and / or the third target absorbance mean includes: obtaining a detection item corresponding to the blood sample to be tested; selecting the first target absorbance mean and / or the third target absorbance mean as a target detection value based on the detection item; calculating the time period corresponding to the target detection value according to a third preset formula to obtain a first sample capacity corresponding to the target detection value; judging whether the first sample capacity is greater than a preset sample capacity; and determining that the blood sample to be tested is a target detection blood sample when the first sample capacity is greater than the preset sample capacity.
[0082] Among them, in the process of determining that the blood sample to be tested is the target detection blood sample according to the first target absorbance mean and / or the third target absorbance mean, it is necessary to first obtain the detection item corresponding to the blood sample to be tested, and the detection item can be set manually or determined according to the blood characteristics of the blood sample to be tested, and there is no sole restriction here; then, according to different detection items, it is determined whether to select the first target absorbance mean as the target detection value, or the third target absorbance mean as the target detection value; or both the first target absorbance mean and the third target absorbance mean are selected as target detection values.
[0083] Specifically, when the first target absorbance mean is selected as the target detection value, the time period corresponding to the first target absorbance mean is calculated according to the third preset formula to obtain the first sample capacity corresponding to the first target absorbance mean; it is determined whether the first sample capacity is greater than the preset sample capacity; when the first sample capacity is greater than the preset sample capacity, it is determined that the blood sample to be tested is the target detection blood sample.
[0084] Specifically, when the third target absorbance mean is selected as the target detection value, the time period corresponding to the third target absorbance mean is calculated according to the third preset formula to obtain the first sample capacity corresponding to the third target absorbance mean; it is determined whether the first sample capacity is greater than the preset sample capacity; when the first sample capacity is greater than the preset sample capacity, it is determined that the blood sample to be tested is the target detection blood sample.
[0085] Specifically, when the first target absorbance mean and the third target absorbance mean are selected as target detection values, the time period corresponding to the first target absorbance mean and the time period corresponding to the third target absorbance mean are calculated respectively according to the third preset formula to obtain the sample capacity corresponding to the first target absorbance mean and the sample capacity corresponding to the third target absorbance mean (note that the sample capacity corresponding to the first target absorbance mean and the sample capacity corresponding to the third target absorbance mean are both referred to as the first sample capacity); determine whether the sample capacity corresponding to the first target absorbance mean and the sample capacity corresponding to the third target absorbance mean are both greater than the preset sample capacity; when the sample capacity corresponding to the first target absorbance mean and the sample capacity corresponding to the third target absorbance mean are both greater than the preset sample capacity, determine that the blood sample to be tested is the target detection blood sample.
[0086] The third preset formula may be: ;
[0087] Where V is the sample volume (ml), Z is the scanning interval, r is the radius of the blood collection tube (cm, mm), π is pi (approximately 3.14159).
[0088] Specifically, the total volume of the sample is calculated by the cross-sectional area of the blood collection tube and the scanning height.
[0089] Among them, the preset sample capacity is the minimum value set based on experimental design or clinical requirements, usually to ensure the accuracy and reliability of experimental results.
[0090] Among them, if the first sample capacity is greater than the preset sample capacity, it can be confirmed that the blood sample to be tested meets the detection requirements, that is, it is the target detection blood sample; if the first sample capacity is less than or equal to the preset sample capacity, the sample may be insufficient and cannot be effectively tested.
[0091] It can be seen that in this embodiment, by analyzing the first target absorbance mean and / or the third target absorbance and calculating the sample capacity, it is possible to effectively determine whether the blood sample to be tested meets the test requirements, which not only optimizes the utilization efficiency of blood samples, but also provides reliable data support for clinical diagnosis.
[0092] S50. Performing a status evaluation on the target detection blood sample according to a preset absorbance threshold interval, the second target absorbance mean value, and the third target absorbance mean value to obtain an evaluation result of the target detection blood sample.
[0093] The above-mentioned preset absorbance threshold interval is a set of absorbance value ranges pre-set in the blood sample status evaluation system, which is used to determine whether the concentration of a specific component in the blood sample is within the normal range. The preset absorbance threshold interval can set different thresholds for different detection purposes.
[0094] Optionally, the above-mentioned preset absorbance threshold interval may include a first preset absorbance threshold interval and a second preset absorbance threshold interval. The first preset absorbance threshold interval may be an interval for hemoglobin Hb (g / L) concentration; the second preset absorbance threshold interval may be an interval for bilirubin TBiL (umol / L) concentration.
[0095] Among them, hemoglobin is the protein in red blood cells responsible for transporting oxygen. Its concentration can reflect the oxygenation capacity of the blood and the anemia condition; bilirubin is an indicator of liver function and the decomposition rate of red blood cells.
[0096] Among them, the status assessment can be to evaluate the status of the blood sample by comparing whether the second and third target absorbance means fall within the corresponding preset absorbance threshold range. If the mean falls within the preset range, it can be judged as normal; if it exceeds the preset range, it may indicate a potential health problem. And if both means are within the corresponding threshold range, the sample status is considered qualified; if any mean is not within the threshold range, the sample status will be evaluated as unqualified and may require further testing or clinical intervention.
[0097] It can be seen that in this embodiment, by combining the preset absorbance threshold interval and the target absorbance mean value, the state of the blood sample can be effectively evaluated.
[0098] By using specific spectral analysis, the method can more accurately evaluate the state of the blood sample. Compared with the traditional subjective observation method, spectral analysis reduces human errors and can provide more objective and accurate data; further calculation of the first target absorbance mean, the second target absorbance mean and the third target absorbance mean makes the sample state evaluation more quantitative and reduces the interference of subjective judgment; further by determining the target detection blood sample, it is possible to quickly screen out samples that meet the requirements, improve detection efficiency, and reduce unnecessary tests; and in combination with the preset absorbance threshold range, the sample state is evaluated, sample abnormalities can be discovered in time, and a basis for subsequent processing can be provided. Therefore, the method reduces the time and errors of manual operation through automated spectral detection and analysis, and significantly improves efficiency and accuracy.
[0099] In a possible example, the preset absorbance threshold interval includes a first preset absorbance threshold interval and a second preset absorbance threshold interval, and the state evaluation of the target detection blood sample is performed according to the preset absorbance threshold interval, the second target absorbance mean value and the third target absorbance mean value to obtain the evaluation result of the target detection blood sample, including: obtaining a first curve corresponding to a preset first detection item and a second curve corresponding to a preset second detection item; substituting the second target absorbance mean value into the first curve to obtain a first detection value under the first curve; substituting the third target absorbance mean value into the second curve to obtain a second detection value under the second curve; judging whether the first detection value is within the first preset absorbance threshold interval and whether the second detection value is within the second preset absorbance threshold interval; if the first detection value is within the first preset absorbance threshold interval and the second detection value is within the second preset absorbance threshold interval, determining that the evaluation result of the target detection blood sample is qualified.
[0100] The first curve and the second curve are calibration curves, which convert the absorbance mean into the actual detection value (such as the concentration of hemoglobin or bilirubin). These curves are obtained through pre-performed experiments and data fitting.
[0101] The first curve is related to the hemoglobin concentration, and is usually a curve of the relationship between hemoglobin and absorbance; the second curve is related to the bilirubin concentration, and is usually a curve of the relationship between bilirubin and absorbance.
[0102] The second target absorbance mean is substituted into the first curve to obtain a first detection value, which represents the hemoglobin concentration calculated based on the absorbance data; the third target absorbance mean is substituted into the second curve to obtain a second detection value, which represents the bilirubin concentration calculated based on the absorbance data.
[0103] Among them, checking whether the first detection value is within the first preset absorbance threshold interval, that is, judging whether the hemoglobin concentration is normal; checking whether the second detection value is within the second preset absorbance threshold interval, that is, judging whether the bilirubin concentration is normal.
[0104] Specifically, if the first detection value and the second detection value are both within their respective preset absorbance threshold intervals, then it can be determined that the evaluation result of the target test blood sample is "qualified", which means that the hemoglobin and bilirubin concentrations in the sample are within the normal range.
[0105] It can be seen that in this embodiment, by substituting the target absorbance mean into the preset curve and comparing it with the threshold, the health status of the blood sample can be effectively evaluated. This process not only optimizes the clinical testing process, but also provides a solid basis for disease prevention and treatment.
[0106] In one possible example, the method for determining whether the first detection value is within the first preset absorbance threshold interval and whether the second detection value is within the second preset absorbance threshold interval also includes: if the first detection value is within the first preset absorbance threshold interval and the second detection value is not within the second preset absorbance threshold interval, determining that the evaluation result of the target detection blood sample is unqualified; or, if the first detection value is not within the first preset absorbance threshold interval and the second detection value is not within the second preset absorbance threshold interval, determining that the evaluation result of the target detection blood sample is unqualified; or, if the first detection value is not within the first preset absorbance threshold interval and the second detection value is within the second preset absorbance threshold interval, determining that the evaluation result of the target detection blood sample is unqualified.
[0107] The above embodiment describes that as long as any test value is not within its preset absorbance threshold range, the evaluation result of the blood sample to be tested will be judged as "unqualified" or "abnormal". This indicates that the concentration of at least one key component in the sample exceeds the normal range, which may indicate a health problem and require further medical examination or intervention.
[0108] Specifically, the first test value is normal, the second test value is abnormal (normal hemoglobin, abnormal bilirubin), the evaluation result: unqualified; the first test value is abnormal, the second test value is normal (abnormal hemoglobin, normal bilirubin), the evaluation result: unqualified; the first test value is abnormal, the second test value is abnormal (abnormal hemoglobin, abnormal bilirubin), the evaluation result: unqualified.
[0109] It can be seen that in this way, in this embodiment, the blood sample status assessment system can help medical professionals quickly identify samples that may pose health risks and take appropriate measures.
[0110] In a possible example, before obtaining the first curve corresponding to the preset first detection item and the second curve corresponding to the preset second detection item, the method further includes: obtaining a preprocessed control blood sample set; controlling the wavelength transmitter to transmit the first type of spectrum and the second type of spectrum to the control blood sample set to obtain a fourth target absorbance region, a fifth target absorbance region, and a sixth target absorbance region of the control blood sample under the first type of spectrum; and obtaining a fourth target absorbance region corresponding to each control blood sample in the fourth target absorbance region according to the fourth target absorbance region, the fifth target absorbance region, and the sixth target absorbance region. The method comprises the steps of: determining the fourth target absorbance mean value and / or the sixth target absorbance mean value of each control blood sample, determining the control blood samples that meet the preset requirements in the control blood sample set as target control blood samples, and obtaining multiple target control blood samples; and calculating according to the fifth target absorbance mean value corresponding to each target control blood sample in the multiple target control blood samples and the sixth target absorbance mean value corresponding to each target control blood sample, to obtain a first curve corresponding to the preset first detection item and a second curve corresponding to the preset second detection item.
[0111] The process of determining the absorbance region in this embodiment is consistent with the description in S20 and will not be repeated here.
[0112] Among them, the fourth target absorbance area may correspond to the absorbance of red blood cells under the first type of spectrum; the fifth target absorbance area may correspond to the absorbance of serum or plasma under the first type of spectrum; and the sixth target absorbance area may correspond to the absorbance of serum or plasma under the second type of spectrum.
[0113] Among them, the fourth target absorbance mean can be obtained by averaging all absorbance values within the fourth target absorbance area, collecting all absorbance values within the fourth target absorbance area, adding these values, and then dividing them by the total number of values to obtain the mean; all absorbance values within the fifth target absorbance area are averaged, and the steps are the same as the fourth target absorbance mean; all absorbance values within the sixth target absorbance area are averaged, and the steps are the same as above.
[0114] Among them, the above preset requirements may be set based on clinical reference values, laboratory standards or historical data, and are not the only limitation here.
[0115] It can be seen that the accuracy and reliability of the calibration curves are ensured in this embodiment. After the calibration curves are established, the absorbance mean values of the blood samples to be tested can be substituted into these curves to predict the concentrations of their components, thereby performing status assessment.
[0116] In a possible example, the step of calculating according to the fifth target absorbance mean corresponding to each target control blood sample in the multiple target control blood samples and the sixth target absorbance mean corresponding to each target control blood sample to obtain a first curve corresponding to the preset first detection item and a second curve corresponding to the preset second detection item includes: obtaining a first target detection value corresponding to each target control blood sample in the multiple target control blood samples, the first target detection value being the detection value corresponding to the preset first detection item; obtaining a second target detection value corresponding to each target control blood sample in the multiple target control blood samples, the second target detection value being the detection value corresponding to the preset second detection item; calculating the first target detection value corresponding to each target control blood sample and the fifth target absorbance mean corresponding to each control blood sample according to a first preset formula to obtain a first curve corresponding to the preset first detection item; and calculating the second target detection value corresponding to each target control blood sample and the sixth target absorbance mean corresponding to each control blood sample according to a second preset formula to obtain a second curve corresponding to the preset second detection item.
[0117] For each target control blood sample, the corresponding first target detection value (hemoglobin concentration) and second target detection value (bilirubin concentration) are obtained. The value does not need to be calculated, and the specific value can be directly obtained.
[0118] The first preset formula is as follows: Hb = 0.0045C Hb ^2 + 0.0012C Hb;
[0119] Among them, C Hb is the fifth target absorbance mean, A Hb is the first curve. This formula indicates that the relationship between the hemoglobin concentration and the absorbance mean is a quadratic function, and thus the hemoglobin concentration range in the blood sample can be determined.
[0120] The second preset formula is as follows: _TBiL = 0.0003C TBiL ^2 + 0.0028C TBiL- 0.0032;
[0121] Among them, C TBiL is the sixth target absorbance mean, A _TBiL The second curve is shown in Figure 2. The formula indicates that the relationship between bilirubin concentration and mean absorbance is a quadratic function, which can be used to evaluate and compare the total bilirubin level in blood samples.
[0122] Among them, the coefficients in the formula (such as 0.0045, 0.0012, 0.0003, 0.0028, etc.) are obtained by fitting experimental data, and they are specific to the instruments, reagents and detection methods used.
[0123] It can be seen that in this embodiment, the calibration curve is ensured to accurately reflect the relationship between the absorbance and the actual detection value, so that in the subsequent blood sample detection, the concentrations of hemoglobin and bilirubin can be accurately predicted by measuring the absorbance.
[0124] It should be noted that, in each of the above-mentioned embodiments, there is not necessarily a certain order between the above-mentioned steps. A person skilled in the art can understand, based on the description of the embodiments of the present application, that in different embodiments, the above-mentioned steps may have different execution orders, that is, they may be executed in parallel, may be executed interchangeably, and so on.
[0125] As another aspect of the embodiment of the present application, the embodiment of the present application provides a blood sample state evaluation system. The blood sample state evaluation system can be a software module, and the software module includes a number of instructions stored in a memory, and the processor can access the memory and call the instructions for execution to complete the blood sample state evaluation method described in each of the above embodiments.
[0126] See also Figure 3 , Figure 3 Schematic diagram of a blood sample status evaluation system provided in an embodiment of the present application. Figure 3 As shown, the blood sample status assessment system includes:
[0127] An acquisition unit 301 is used to acquire a pre-processed blood sample to be tested;
[0128] The determining unit 302 is used to control the wavelength transmitter in the blood sample state evaluation system to transmit the first type of spectrum and the second type of spectrum to the blood sample to be detected, so as to obtain a first target absorbance region, a second target absorbance region and a third target absorbance region of the blood sample to be detected under the first type of spectrum;
[0129] The determining unit 302 is further configured to obtain, according to the first target absorbance region, the second target absorbance region and the third target absorbance region, a first target absorbance mean corresponding to the first target absorbance region, a second target absorbance mean corresponding to the second target absorbance region and a third target absorbance mean corresponding to the third target absorbance region;
[0130] The determining unit 302 is further configured to determine that the blood sample to be tested is a target test blood sample according to the first target absorbance mean value and / or the third target absorbance mean value;
[0131] The evaluation unit 303 is used to perform a state evaluation on the target detection blood sample according to a preset absorbance threshold interval, the second target absorbance mean value and the third target absorbance mean value to obtain an evaluation result of the target detection blood sample.
[0132] By using specific spectral analysis, the method can more accurately evaluate the state of the blood sample. Compared with the traditional subjective observation method, spectral analysis reduces human errors and can provide more objective and accurate data; further calculation of the first target absorbance mean, the second target absorbance mean and the third target absorbance mean makes the sample state evaluation more quantitative and reduces the interference of subjective judgment; further by determining the target detection blood sample, it is possible to quickly screen out samples that meet the requirements, improve detection efficiency, and reduce unnecessary tests; and in combination with the preset absorbance threshold range, the sample state is evaluated, sample abnormalities can be discovered in time, and a basis for subsequent processing can be provided. Therefore, the method reduces the time and errors of manual operation through automated spectral detection and analysis, and significantly improves efficiency and accuracy.
[0133] In one embodiment, the preset absorbance threshold interval includes a first preset absorbance threshold interval and a second preset absorbance threshold interval, and in the state evaluation of the target detection blood sample according to the preset absorbance threshold interval, the second target absorbance mean value and the third target absorbance mean value to obtain the evaluation result of the target detection blood sample, the evaluation unit 303 is further used to: obtain a first curve corresponding to a preset first detection item and a second curve corresponding to a preset second detection item; substitute the second target absorbance mean value into the first curve to obtain a first detection value under the first curve; substitute the third target absorbance mean value into the second curve to obtain a second detection value under the second curve; determine whether the first detection value is within the first preset absorbance threshold interval and whether the second detection value is within the second preset absorbance threshold interval; if the first detection value is within the first preset absorbance threshold interval and the second detection value is within the second preset absorbance threshold interval, determine that the evaluation result of the target detection blood sample is qualified.
[0134] In one embodiment, in the determination of whether the first detection value is within the first preset absorbance threshold interval and whether the second detection value is within the second preset absorbance threshold interval, the evaluation unit 303 is further used to: if the first detection value is within the first preset absorbance threshold interval and the second detection value is not within the second preset absorbance threshold interval, determine that the evaluation result of the target detection blood sample is unqualified; or, if the first detection value is not within the first preset absorbance threshold interval and the second detection value is not within the second preset absorbance threshold interval, determine that the evaluation result of the target detection blood sample is unqualified; or, if the first detection value is not within the first preset absorbance threshold interval and the second detection value is within the second preset absorbance threshold interval, determine that the evaluation result of the target detection blood sample is unqualified.
[0135] In one embodiment, before obtaining the first curve corresponding to the preset first detection item and the second curve corresponding to the preset second detection item, the evaluation unit 303 is further used to: obtain a pre-processed control blood sample set; control the wavelength transmitter to transmit the first type of spectrum and the second type of spectrum to the control blood sample set to obtain a fourth target absorbance region, a fifth target absorbance region and a sixth target absorbance region of the control blood sample under the first type of spectrum and under the second type of spectrum; obtain the fourth target absorbance region corresponding to each control blood sample according to the fourth target absorbance region, the fifth target absorbance region and the sixth target absorbance region; target absorbance mean, the fifth target absorbance mean corresponding to the fifth target absorbance area, and the sixth target absorbance mean corresponding to the sixth target absorbance mean in the sixth target absorbance area; according to the fourth target absorbance mean and / or the sixth target absorbance mean of each control blood sample, determine the control blood samples that meet the preset requirements in the control blood sample set as target control blood samples, and obtain multiple target control blood samples; calculate according to the fifth target absorbance mean corresponding to each target control blood sample in the multiple target control blood samples and the sixth target absorbance mean corresponding to each target control blood sample, to obtain a first curve corresponding to the preset first detection item and a second curve corresponding to the preset second detection item.
[0136] In one embodiment, in the step of calculating the fifth target absorbance mean corresponding to each target control blood sample in the multiple target control blood samples and the sixth target absorbance mean corresponding to each target control blood sample to obtain the first curve corresponding to the preset first detection item and the second curve corresponding to the preset second detection item, the evaluation unit 303 is further used to: obtain a first target detection value corresponding to each target control blood sample in the multiple target control blood samples, the first target detection value being the detection value corresponding to the preset first detection item; obtain a second target detection value corresponding to each target control blood sample in the multiple target control blood samples, the second target detection value being the detection value corresponding to the preset second detection item; calculate the first target detection value corresponding to each target control blood sample and the fifth target absorbance mean corresponding to each control blood sample according to a first preset formula to obtain the first curve corresponding to the preset first detection item; calculate the second target detection value corresponding to each target control blood sample and the sixth target absorbance mean corresponding to each control blood sample according to a second preset formula to obtain the second curve corresponding to the preset second detection item.
[0137] In one embodiment, in controlling the wavelength transmitter in the blood sample state evaluation system to transmit the first type of spectrum and the second type of spectrum to the blood sample to be detected, and obtaining the first target absorbance region, the second target absorbance region and the third target absorbance region of the blood sample to be detected under the first type of spectrum, the determining unit 302 is further used to: control the wavelength transmitter in the blood sample state evaluation system to transmit the first type of spectrum and the second type of spectrum to the blood sample to be detected at a preset absorbance point frequency, and obtain the first absorbance region corresponding to the first type of spectrum. A photometric point sequence and a second absorbance point sequence corresponding to the second type of spectrum; in the first absorbance point sequence, absorbance region judgment is performed from top to bottom in turn to obtain a first absorbance region, a second absorbance region and a third absorbance region; the third absorbance region is determined to be a first target absorbance region and the first absorbance region is determined to be a second target absorbance region; in the second absorbance point sequence, the absorbance region judgment is performed from top to bottom in turn to obtain a fourth absorbance region, a fifth absorbance region and a sixth absorbance region; the fourth absorbance region is determined to be a third target absorbance region.
[0138] In one embodiment, the absorbance region is determined as a target absorbance region in which the intercept of two adjacent absorbance points in the first absorbance point sequence or the second absorbance point sequence is greater than 0 and is detected in continuous scanning until the intercept of two adjacent absorbance points is less than 0.
[0139] In one embodiment, in the process of obtaining the first target absorbance mean corresponding to the first target absorbance area, the second target absorbance mean corresponding to the second target absorbance area, and the third target absorbance mean corresponding to the third target absorbance area according to the first target absorbance area, the second target absorbance mean corresponding to the second target absorbance area, and the third target absorbance mean corresponding to the third target absorbance area, the determining unit 302 is further used to: obtain a first time period corresponding to the first target absorbance area, a second time period corresponding to the second target absorbance area, and a third time period corresponding to the third target absorbance area; obtain the first target absorbance mean according to the value of each absorbance in the first target absorbance area and the first time period; obtain the second target absorbance mean according to the value of each absorbance in the second target absorbance area and the second time period; obtain the third target absorbance mean according to the value of each absorbance in the third target absorbance area and the third time period.
[0140] In one embodiment, in determining that the blood sample to be tested is a target detection blood sample based on the first target absorbance mean value and / or the third target absorbance mean value, the determination unit 302 is further used to: obtain a detection item corresponding to the blood sample to be tested; select the first target absorbance mean value and / or the third target absorbance mean value as a target detection value based on the detection item; calculate the time period corresponding to the target detection value according to a third preset formula to obtain a first sample capacity corresponding to the target detection value; determine whether the first sample capacity is greater than a preset sample capacity; when the first sample capacity is greater than the preset sample capacity, determine that the blood sample to be tested is a target detection blood sample.
[0141] The blood sample status evaluation system can also be constructed by hardware devices. For example, the blood sample status evaluation system can be constructed by one or more chips, and each chip can work in coordination with each other to complete the blood sample status evaluation method described in each of the above embodiments. For another example, the blood sample status evaluation system can also be constructed by various logic devices, such as a general-purpose processor, a digital signal processor (DSP), an application-specific integrated circuit (ASIC), a field programmable gate array (FPGA), a single-chip microcomputer, an ARM (Acorn RISC Machine) or other programmable logic devices, discrete gate or transistor logic, discrete hardware components, or any combination of these components.
[0142] It should be noted that the above-mentioned blood sample status evaluation system can execute the blood sample status evaluation method provided in the embodiment of the present application, and has the corresponding functional modules and beneficial effects of the execution method. For technical details not fully described in the embodiment of the blood sample status evaluation system, please refer to the blood sample status evaluation method provided in the embodiment of the present application.
[0143] See also Figure 4 , Figure 4 4 is a schematic diagram of a computer device provided in an embodiment of the present application. The computer device includes one or more processors 41 and a memory 42. The memory 42 is connected to the one or more processors 41, for example, connected to the processor 41 via a bus.
[0144] The processor 41 is configured to support the computer device to perform the corresponding functions in the method in the above method embodiment. The processor 41 can be a central processing unit (CPU), a network processor (NP), a hardware chip or any combination thereof. The above hardware chip can be an application specific integrated circuit (ASIC), a programmable logic device (PLD) or a combination thereof. The above PLD can be a complex programmable logic device (CPLD), a field-programmable gate array (FPGA), a generic array logic (GAL) or any combination thereof.
[0145] The memory 42 is used to store program codes, etc. The memory 42 may include a volatile memory (VM), such as a random access memory (RAM); the memory 42 may also include a non-volatile memory (NVM), such as a read-only memory (ROM), a flash memory, a hard disk drive (HDD) or a solid-state drive (SSD); the memory 42 may also include a combination of the above-mentioned types of memories.
[0146] The memory 42 can be used to store non-volatile software programs, non-volatile computer executable programs and modules, such as program instructions / modules corresponding to the vehicle diagnostic method in the embodiment of the present application. The processor 41 executes the various functional applications and data processing of the vehicle diagnostic method and computer equipment by running the non-volatile software programs, instructions and modules stored in the memory, that is, realizes the functions of the vehicle diagnostic method and various modules or units of the computer equipment provided in the above method embodiment.
[0147] The memory 42 may include a program storage area and a data storage area, wherein the program storage area may store an operating system and an application required for at least one function. The data storage area may store data created according to the use of the vehicle diagnostic device, etc. In some embodiments, the memory 42 may optionally include a memory remotely arranged relative to the processor, and these remote memories may be connected to the vehicle diagnostic device via a network. Examples of the above-mentioned network include, but are not limited to, the Internet, an intranet, a local area network, a mobile communication network, and combinations thereof.
[0148] The one or more modules are stored in the memory, and when executed by the one or more processors, the blood sample status assessment method in any of the above method embodiments is executed, for example, the method steps described in the above method embodiments are executed to realize the functions of the modules described in the above device embodiments.
[0149] An embodiment of the present application further provides a computer-readable storage medium, wherein the computer-readable storage medium stores a computer program, wherein the computer program includes program instructions, and when the program instructions are executed by a computer, the computer executes the method described in the above embodiment.
[0150] A person skilled in the art can understand that all or part of the processes in the above-mentioned embodiments can be implemented by instructing the relevant hardware through a computer program, and the program can be stored in a computer-readable storage medium, and when the program is executed, it can include the processes of the embodiments of the above-mentioned methods. The storage medium can be a disk, an optical disk, a read-only memory (ROM) or a random access memory (RAM), etc.
[0151] The above disclosure is only the preferred embodiment of the present application, which certainly cannot be used to limit the scope of rights of the present application. Therefore, equivalent changes made according to the claims of the present application are still within the scope covered by the present application.
Claims
1. A method for evaluating the status of a blood sample, characterized in that: Applied to a blood sample status assessment system, the method comprises: Obtaining a pre-treated blood sample to be tested; Controlling the wavelength transmitter in the blood sample state evaluation system to transmit a first type of spectrum and a second type of spectrum to the blood sample to be detected, and obtaining a first target absorbance region, a second target absorbance region and a third target absorbance region of the blood sample to be detected under the first type of spectrum; According to the first target absorbance region, the second target absorbance region and the third target absorbance region, a first target absorbance mean corresponding to the first target absorbance region, a second target absorbance mean corresponding to the second target absorbance region and a third target absorbance mean corresponding to the third target absorbance region are obtained; Determining the blood sample to be tested as a target test blood sample according to the first target absorbance mean value and / or the third target absorbance mean value; Performing a state evaluation on the target detection blood sample according to a preset absorbance threshold interval, the second target absorbance mean value, and the third target absorbance mean value to obtain an evaluation result of the target detection blood sample; The preset absorbance threshold interval includes a first preset absorbance threshold interval and a second preset absorbance threshold interval, and the state evaluation of the target detection blood sample is performed according to the preset absorbance threshold interval, the second target absorbance mean value, and the third target absorbance mean value to obtain the evaluation result of the target detection blood sample, including: Obtaining a first curve corresponding to a preset first detection item and a second curve corresponding to a preset second detection item; Substituting the second target absorbance mean into the first curve to obtain a first detection value under the first curve; Substituting the third target absorbance mean into the second curve to obtain a second detection value under the second curve; Determining whether the first detection value is within the first preset absorbance threshold interval and whether the second detection value is within the second preset absorbance threshold interval; If the first detection value is within the first preset absorbance threshold interval, and the second detection value is within the second preset absorbance threshold interval, determining that the evaluation result of the target test blood sample is qualified; The step of controlling the wavelength transmitter in the blood sample state evaluation system to transmit the first type of spectrum and the second type of spectrum to the blood sample to be detected, and obtaining the first target absorbance region, the second target absorbance region and the third target absorbance region of the blood sample to be detected under the first type of spectrum, comprises: Controlling the wavelength transmitter in the blood sample status evaluation system to transmit the first type of spectrum and the second type of spectrum to the blood sample to be detected at a preset absorbance point frequency, and obtaining a first absorbance point sequence corresponding to the first type of spectrum and a second absorbance point sequence corresponding to the second type of spectrum; In the first absorbance point sequence, absorbance region judgment is performed from top to bottom to obtain a first absorbance region, a second absorbance region and a third absorbance region; Determining the third absorbance region as a first target absorbance region and determining the first absorbance region as a second target absorbance region; In the second absorbance point sequence, the absorbance region judgment is performed from top to bottom to obtain a fourth absorbance region, a fifth absorbance region and a sixth absorbance region; Determining the fourth absorbance region as a third target absorbance region; Wherein, determining the blood sample to be tested as a target test blood sample according to the first target absorbance mean value and / or the third target absorbance mean value includes: Obtaining the test items corresponding to the blood sample to be tested; According to the detection item, selecting the first target absorbance mean value and / or the third target absorbance mean value as the target detection value; Calculating the time period corresponding to the target detection value according to a third preset formula to obtain a first sample size corresponding to the target detection value; Determining whether the first sample size is greater than a preset sample size; When the first sample capacity is greater than the preset sample capacity, the to-be-detected blood sample is determined to be a target detection blood sample.
2. The blood sample status evaluation method according to claim 1, characterized in that: The method of determining whether the first detection value is within the first preset absorbance threshold interval and whether the second detection value is within the second preset absorbance threshold interval further includes: If the first detection value is within the first preset absorbance threshold interval, and the second detection value is not within the second preset absorbance threshold interval, then the evaluation result of the target test blood sample is determined to be unqualified; or, If the first detection value is not within the first preset absorbance threshold interval, and the second detection value is not within the second preset absorbance threshold interval, then the evaluation result of the target test blood sample is determined to be unqualified; or, If the first detection value is not within the first preset absorbance threshold interval, and the second detection value is within the second preset absorbance threshold interval, it is determined that the evaluation result of the target detection blood sample is unqualified.
3. The blood sample status evaluation method according to claim 1, characterized in that: Before obtaining the first curve corresponding to the preset first detection item and the second curve corresponding to the preset second detection item, the method further includes: obtaining a set of pre-treated control blood samples; Controlling the wavelength transmitter to transmit the first type of spectrum and the second type of spectrum to the control blood sample set, to obtain a fourth target absorbance region and a fifth target absorbance region of the control blood sample under the first type of spectrum and a sixth target absorbance region under the second type of spectrum; According to the fourth target absorbance region, the fifth target absorbance region and the sixth target absorbance region corresponding to each control blood sample, a fourth target absorbance mean corresponding to the fourth target absorbance region, a fifth target absorbance mean corresponding to the fifth target absorbance region and a sixth target absorbance mean corresponding to the sixth target absorbance region of each control blood sample are obtained; According to the fourth target absorbance mean value and / or the sixth target absorbance mean value of each control blood sample, determining a control blood sample in the control blood sample set that meets preset requirements as a target control blood sample, to obtain a plurality of target control blood samples; Calculation is performed based on the fifth target absorbance mean corresponding to each target control blood sample in the multiple target control blood samples and the sixth target absorbance mean corresponding to each target control blood sample to obtain a first curve corresponding to the preset first detection item and a second curve corresponding to the preset second detection item.
4. The blood sample status evaluation method according to claim 3, characterized in that: The step of calculating according to the fifth target absorbance mean corresponding to each target control blood sample in the multiple target control blood samples and the sixth target absorbance mean corresponding to each target control blood sample to obtain a first curve corresponding to the preset first detection item and a second curve corresponding to the preset second detection item includes: Acquire a first target detection value corresponding to each target control blood sample in the multiple target control blood samples, where the first target detection value is a detection value corresponding to the preset first detection item; Acquire a second target detection value corresponding to each target control blood sample in the multiple target control blood samples, where the second target detection value is a detection value corresponding to the preset second detection item; According to a first preset formula, the first target detection value corresponding to each target control blood sample and the fifth target absorbance mean corresponding to each control blood sample are calculated to obtain a first curve corresponding to the preset first detection item; According to the second preset formula, the second target detection value corresponding to each target control blood sample and the sixth target absorbance mean corresponding to each control blood sample are calculated to obtain a second curve corresponding to the preset second detection item.
5. The blood sample status evaluation method according to claim 1, characterized in that: The absorbance region is determined as a target absorbance region in which the intercept of two adjacent absorbance points in the first absorbance point sequence or the second absorbance point sequence is greater than 0 and is detected in continuous scanning until the intercept of two adjacent absorbance points is less than 0.
6. The blood sample status evaluation method according to claim 1, characterized in that: Therefore, according to the first target absorbance region, the second target absorbance region and the third target absorbance region, the first target absorbance mean corresponding to the first target absorbance region, the second target absorbance mean corresponding to the second target absorbance region and the third target absorbance mean corresponding to the third target absorbance region are obtained, including: Acquire a first time period corresponding to the first target absorbance region, a second time period corresponding to the second target absorbance region, and a third time period corresponding to the third target absorbance region; Obtaining the first target absorbance mean value according to the value of each absorbance in the first target absorbance region and the first time period; Obtaining the second target absorbance mean value according to the value of each absorbance in the second target absorbance region and the second time period; The third target absorbance mean value is obtained according to the value of each absorbance in the third target absorbance region and the third time period.
7. A blood sample status assessment system, characterized in that: The method for evaluating the state of a blood sample according to any one of claims 1 to 6 is used, wherein the blood sample state evaluation system comprises: An acquisition unit, used for acquiring a pre-treated blood sample to be tested; a determination unit, configured to control the wavelength transmitter in the blood sample state evaluation system to transmit a first type of spectrum and a second type of spectrum to the blood sample to be detected, so as to obtain a first target absorbance region, a second target absorbance region and a third target absorbance region of the blood sample to be detected under the first type of spectrum; The determining unit is further configured to obtain, according to the first target absorbance region, the second target absorbance region and the third target absorbance region, a first target absorbance mean corresponding to the first target absorbance region, a second target absorbance mean corresponding to the second target absorbance region and a third target absorbance mean corresponding to the third target absorbance region; The determining unit is further used to determine that the blood sample to be tested is a target test blood sample according to the first target absorbance mean value and / or the third target absorbance mean value; An evaluation unit is used to perform a status evaluation on the target detection blood sample according to a preset absorbance threshold interval, the second target absorbance mean value and the third target absorbance mean value to obtain an evaluation result of the target detection blood sample.
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