A biochemical immunoassay device for reproductive medicine

Abstract

The present invention relates to a reproductive medicine biochemical immunoassay device applied to the field of reproductive medicine detection, comprising a detection cabin and a test tube rack detachably installed in the detection cabin, a detector is installed at the upper end of the detection cabin, the detector comprises a detection probe which can move up and down, a cleaning sleeve is fixed to the top wall in the detection cabin, a wiping cotton ring is fixed to the outer wall of the cleaning sleeve, and a liquid absorption layer is filled between a partition plate and a bottom wall of the cleaning sleeve. By adopting the above-mentioned cleaning sleeve, wiping cotton ring and liquid absorption layer and other structures, compared with the repeated positioning mobile cleaning method in the prior art, the reproductive medicine biochemical immunoassay device omits the action of changing the workstation while ensuring the cleaning effect, and the repeated detection speed is faster, which can speed up the detection efficiency, and also saves the repeated positioning action, avoids the deviation that may be caused in the repeated positioning process, improves the detection accuracy of the detection probe in the detection process, improves the detection effect, and has a better comprehensive use effect.

Description

Technical Field

[0001] The present invention relates to a biochemical immune detection device, in particular to a reproductive medicine biochemical immune detection device applied in the field of reproductive medicine detection. Background Art

[0002] Reproductive immunology is an emerging discipline that can examine recurrent miscarriage, especially miscarriage caused by autoimmune diseases. It can also examine the causes of repeated implantation failures of esophageal polycystic ovary syndrome and repeated biochemical pregnancies, and provide targeted treatment. Reproductive immunology is an interdisciplinary discipline that has developed on the basis of obstetrics and gynecology, reproductive medicine, and rheumatology and immunology. Immunoglobulin content, classification and counting of immune cells, phagocytic function of neutrophils, etc. are all common examination items in the reproductive immunology department.

[0003] However, the traditional reproductive medicine biochemical immunoassay equipment is not convenient for fixing the test tubes. After being placed in the test equipment, the test tubes are easily shaken and the test samples inside are easily leaked, which will cause the spread of germs and viruses and pollute the workplace. In addition, the test tube rack of the above solution is not convenient for better rotation, so it is not convenient to better compare and test multiple samples together.

[0004] To solve the above problems, the Chinese patent CN220105050U specification discloses a biochemical immunoassay device for reproductive medicine, including: a workbench; a cylinder, which is movably installed inside the workbench, and a gear 1 is fixedly installed on the outer surface of the cylinder; two test tube racks, which are fixedly installed inside the cylinder. The test tube is placed inside the test tube rack through the placement hole, and a rectangular plate is fixedly installed on the outer surface of one of the test tube racks, and a telescopic rod is fixedly installed on the opposite back of the rectangular plate. One end of each of the multiple telescopic rods is fixedly installed with an arc plate, and the two arc plates can better adjust the elastic force of the spring, and the arc plate can better clamp and fix the test tube to prevent the test tube from shaking and causing the internal sample to leak, thereby causing pollution to the workbench and the surrounding working environment. The outer surfaces of the two arc plates are fixedly installed with multiple rubber strips, which can increase the friction, better prevent the test tube from shaking, and can also protect the test tube.

[0005] Although the reproductive medicine biochemical immunoassay equipment in the prior art can meet the basic use requirements, in actual use, the detection probe on the detector (the detection component of the above document) needs to be cleaned during use, that is, after completing a sample test, the surface of the detection probe needs to be cleaned so that the probe surface remains clean and the accuracy of the test results is ensured;

[0006] However, in the prior art, the detection probe needs to be rotated to a cleaning station, cleaned with a cleaning piece, and then rotated to the detection station again for detection. This step not only increases the detection time interval between the two samples, but is also prone to position deviations during repeated positioning, affecting the detection accuracy and may also cause errors in the detection results. Summary of the invention

[0007] In view of the above-mentioned prior art, the technical problem to be solved by the present invention is how to provide a reproductive medicine biochemical immunoassay detection device that can provide better self-cleaning effect of the detection probe, reduce the detection interval of the detection probe, and avoid the positioning error caused by repeated positioning, which leads to a decrease in detection accuracy.

[0008] In order to solve the above problems, the present invention provides a biochemical immunoassay device for reproductive medicine, comprising a test chamber and a test tube rack detachably mounted in the test chamber, a detector is mounted on the upper end of the test chamber, the detector comprises a detection probe that is located in the test chamber and can move up and down, and a driving shaft that drives the test tube rack to rotate through a linkage is also mounted in the test chamber;

[0009] A cleaning sleeve is fixed to the top wall of the detection chamber, and a middle through hole is provided in the middle of the cleaning sleeve for the detection probe to penetrate. A mass chamber filled with cleaning liquid is formed between the inner and outer side walls of the upper end of the cleaning sleeve, and a wiping cotton ring is fixed to the outer wall of the cleaning sleeve. The wiping cotton ring is located below the mass chamber and is connected to the mass chamber through a liquid pressure plate in a closure manner. A partition plate is formed at the lower end of the wiping cotton ring, and the lower end of the partition plate is fixed to the outer wall of the cleaning sleeve.

[0010] A liquid absorbing layer is filled between the partition plate and the bottom wall of the cleaning sleeve, and a limiting membrane for limiting the liquid absorbing layer is arranged between the partition plate and the bottom wall of the cleaning sleeve, and the limiting membrane has good water permeability;

[0011] The inner wall of the wiping cotton ring and the inner wall of the limiting membrane outside the liquid absorption layer have the same size and structure as the inner wall of the middle through hole.

[0012] In the above-mentioned reproductive medicine biochemical immunology detection equipment, when the detection probe rises, the detection probe enters the middle through hole in the cleaning sleeve from the lower end, and makes the lower end of the detection probe located inside or above the wiping cotton ring, so that the wiping cotton ring wipes the surface of the detection probe once, and then the detection probe descends, so that the wiping cotton ring wipes the surface of the detection probe a second time. As the detection probe descends, the waste liquid remaining on the surface of the detection probe after wiping and the waste liquid sliding down from the inner surface of the wiping cotton ring are absorbed by the liquid absorption layer, so that the detection probe leaving the cleaning sleeve is cleaned and the surface remains dry, thereby facilitating the cleaning of the detection probe, so that the detection probe is always kept clean, and the validity of the detection result is ensured;

[0013] Compared with the prior art which requires moving the detection probe into a cleaning station for cleaning and then moving it back to the detection station for testing, the reproductive medicine biochemical immunoassay detection equipment omits the action of changing stations while ensuring the cleaning effect. The repeated detection speed is faster, which can speed up the detection efficiency. At the same time, it also saves repeated positioning actions, avoids the deviation that may be caused by repeated positioning, improves the detection accuracy of the detection probe during the detection process, improves the detection effect, and has a better overall use effect.

[0014] As a further supplement to the present application, a waste liquid storage bin is fixed and connected to the lower end of the cleaning sleeve, and a pumping mechanism for extracting waste liquid from the waste liquid storage bin is installed on the outer side of the cleaning sleeve;

[0015] An adjustable linkage rod is installed at the upper end of the liquid pressure plate. The adjustable linkage rod is used to drive the liquid pressure plate to rise and fall and enable the liquid pressure plate to press the cleaning fluid in the volume cavity into the wiping cotton ring.

[0016] As a further supplement to the present application, the liquid pressure plate includes a fixed disk and a soft plug plate. The fixed disk is located at the upper end of the soft plug plate and is fixedly connected to the lower end of the adjustable linkage rod. The fixed disk is made of a hard material and has a plurality of evenly distributed disk holes. The soft plug plate is made of a flexible material, and the upper end of the inner circle of the soft plug plate is fixed to the lower end of the inner circle of the fixed disk, and the fixed disk is separated from the outer circle of the soft plug plate.

[0017] As a further supplement to the present application, the adjustable linkage rod includes:

[0018] Connecting sleeve 1, the lower end of the connecting sleeve is fixed to the upper end of the fixing plate;

[0019] A linkage rod, the linkage rod is slidably connected in the connecting sleeve 1, the upper end of the linkage rod is fixed to the upper end of the detection probe through a connecting piece and rises and falls synchronously with the detection probe;

[0020] The lower end of the linkage rod is provided with a limiting piece to prevent the linkage rod from being separated from the connecting sleeve.

[0021] As a further supplement to the present application, the limiting member includes a limiting collar, the upper end of which is fixed with a connecting sleeve 2 slidably sleeved on the linkage rod, and the upper end of the connecting sleeve 2 slides through the top of the connecting sleeve 1;

[0022] An adjusting ring is fixed at the upper end of the second connecting sleeve, a threaded portion is arranged in the middle of the linkage rod, and an internal thread matching the threaded portion is arranged in the adjusting ring;

[0023] The limiting collar is slidably sleeved on the linkage rod.

[0024] As a further supplement to the present application, a sewage outlet is provided at the lower end of the cleaning sleeve, a sewage inlet connected to the sewage outlet is provided at the upper end of the waste liquid holding chamber, and a first one-way structure is installed in the sewage outlet and the waste liquid holding chamber;

[0025] The first unidirectional structure includes a first fixed rod, a first spring and a first blocking piece. The first fixed rod is horizontally arranged and both ends are fixed to the two ends of the inner wall of the sewage outlet. The upper and lower ends of the first spring are respectively fixed to the first fixed rod and the lower end of the first spring passes through the sewage inlet and is located in the waste liquid holding chamber. The first blocking piece is located in the waste liquid holding chamber and has a diameter greater than the inner diameter of the sewage inlet.

[0026] As a further supplement to this application, the extraction mechanism includes:

[0027] A delivery pipe, the lower end of which is fixed and connected to the waste liquid storage bin through a connecting elbow, and a transfer hole connected to an external sewage pipe is provided on one side of the upper end of the delivery pipe;

[0028] A piston rod, the piston rod is slidably connected in the delivery tube and the upper end of the piston rod slides through the upper end of the delivery tube, a seal is formed between the upper end of the piston rod and the upper end of the delivery tube, and the upper end of the piston rod is also fixed to the upper end of the detection probe through a connecting piece and rises and falls synchronously with the detection probe;

[0029] The piston is fixed at the lower end of the piston rod, the circumference of the piston is interference fit with the inner wall of the delivery pipe, and a plurality of evenly distributed through holes are opened on the piston;

[0030] A second one-way structure for preventing sewage from flowing back is installed in each of the plurality of through holes.

[0031] As a further supplement to the present application, the second unidirectional structure includes a second fixed rod, a second spring and a second blocking piece. The second fixed rod is horizontally arranged and both ends are fixed to the inner wall of the through hole. The lower end of the second spring is fixed to the upper end of the second fixed rod. The upper end of the second spring passes through the through hole and is fixed to the lower end of the second blocking piece. The diameter of the second blocking piece is larger than the inner diameter of the through hole.

[0032] As a further supplement to the present application, a probe seat is fixed to the upper end of the detection probe, and the connecting part includes a mounting rod, one end of the mounting rod is fixed to one side of the probe seat, and the lower end of the mounting rod is respectively fixed to the upper end of the linkage rod and the upper end of the piston rod.

[0033] To summarize, when the detection probe rises, the detection probe enters the middle through hole in the cleaning sleeve from the lower end, and the lower end of the detection probe is located inside or above the wiping cotton ring, so that the wiping cotton ring wipes the surface of the detection probe once, and then the detection probe descends, so that the wiping cotton ring wipes the surface of the detection probe twice. As the detection probe descends, the waste liquid remaining on the surface of the detection probe after wiping and the waste liquid sliding down from the inner surface of the wiping cotton ring are absorbed by the liquid absorption layer, so that the detection probe leaving the cleaning sleeve is cleaned and the surface remains dry, so as to facilitate the cleaning of the detection probe, so that the detection probe is always kept clean, and the validity of the detection result is guaranteed;

[0034] Compared with the prior art which requires moving the detection probe into a cleaning station for cleaning and then moving it back to the detection station for testing, the reproductive medicine biochemical immunoassay detection equipment omits the action of changing stations while ensuring the cleaning effect. The repeated detection speed is faster, which can speed up the detection efficiency. At the same time, it also saves repeated positioning actions, avoids the deviation that may be caused by repeated positioning, improves the detection accuracy of the detection probe during the detection process, improves the detection effect, and has a better overall use effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] Figure 1 This is a schematic diagram of the three-dimensional structure of the first embodiment of the present application;

[0036] Figure 2 This is a schematic diagram of the three-dimensional structure after the cleaning sleeve is hidden in the first embodiment of the present application;

[0037] Figure 3 This is an enlarged view of the cleaning sleeve part of the first embodiment of the present application;

[0038] Figure 4 This is a cross-sectional view of the cleaning sleeve of the first embodiment of the present application;

[0039] Figure 5 for Figure 4 A magnified view of the structure at center;

[0040] Figure 6 A partial cross-sectional view of the pumping mechanism and the second one-way structure of the first embodiment of the present application;

[0041] Figure 7 This is a partial cross-sectional view of the adjustable linkage rod according to the first embodiment of the present application;

[0042] Figure 8 This is a separation diagram of the pressure plate of the first embodiment of the present application.

[0043] Description of the numbers in the figure:

[0044] 1. Detection chamber; 2. Test tube rack; 3. Detector; 301. Detection probe; 302. Probe seat; 303. Mounting rod; 4. Drive shaft; 5. Cleaning sleeve; 501. Middle through hole; 502. Mass chamber; 503. Separator; 504. Drain port; 6. Wiping cotton ring; 7. Liquid absorption layer; 8. Liquid pressure plate; 801. Fixed plate; 802. Plate hole; 803. Soft plug; 9. Adjustable linkage rod; 901. Connecting sleeve 1; 902. Linkage rod; 903. Threaded part; 904. Limiting collar; 90 5. Connecting sleeve 2; 906. Adjusting ring; 10. Pumping mechanism; 1001. Delivery pipe; 1002. Piston rod; 1003. Piston; 1004. Through hole; 1005. Adapter hole; 11. Waste liquid storage bin; 1101. Sewage inlet; 12. First one-way structure; 1201. First fixing rod; 1202. First spring; 1203. First blocking piece; 13. Second one-way structure; 1301. Second fixing rod; 1302. Second spring; 1303. Second blocking piece; 14. Connecting elbow. DETAILED DESCRIPTION

[0045] An implementation method of the present application is described in detail below with reference to the accompanying drawings.

[0046] The first implementation method:

[0047] The present invention provides a reproductive medicine biochemical immunoassay device, please refer to Figure 1-Figure 4 , comprising a detection chamber 1 and a test tube rack 2 detachably mounted in the detection chamber 1, a detector 3 is mounted on the upper end of the detection chamber 1, the detector 3 comprises a detection probe 301 located in the detection chamber 1 and movable up and down, and a driving shaft 4 is also mounted in the detection chamber 1 for driving the test tube rack 2 to rotate through a linkage;

[0048] A cleaning sleeve 5 is fixed to the top wall of the detection chamber 1, and a middle through hole 501 is provided in the middle of the cleaning sleeve 5 for the detection probe 301 to pass through. A mass chamber 502 filled with cleaning liquid is formed between the inner and outer side walls of the upper end of the cleaning sleeve 5, and an openable closed mouth is formed at the upper end of the mass chamber 502, so as to facilitate the addition of cleaning liquid into the mass chamber 502 and to seal the mass chamber 502. A wiping cotton ring 6 is fixed to the outer wall of the cleaning sleeve 5, and the wiping cotton ring 6 is located below the mass chamber 502 and is closably connected to the mass chamber 502 through the liquid pressure plate 8. A partition plate 503 is formed at the lower end of the wiping cotton ring 6 and is arranged obliquely and fixed to the outer wall of the cleaning sleeve 5 at the lower end;

[0049] A liquid absorbing layer 7 is filled between the partition plate 503 and the bottom wall of the cleaning sleeve 5. A limiting membrane is provided between the partition plate 503 and the bottom wall of the cleaning sleeve 5 to limit the liquid absorbing layer 7. The limiting membrane has good water permeability.

[0050] The inner wall of the wiping cotton ring 6 and the inner wall of the limiting membrane outside the liquid-absorbing layer 7 have the same size and structure as the inner wall of the middle through hole 501 .

[0051] Based on the above structure, when the detection probe 301 rises, the detection probe 301 enters the middle through hole 501 in the cleaning sleeve 5 from the lower end, and the lower end of the detection probe 301 is located inside or above the wiping cotton ring 6, so that the wiping cotton ring 6 wipes the surface of the detection probe 301 once, and then the detection probe 301 descends, so that the wiping cotton ring 6 wipes the surface of the detection probe 301 twice. As the detection probe 301 descends, the waste liquid remaining on the surface of the detection probe 301 after wiping and the waste liquid sliding down from the inner surface of the wiping cotton ring 6 are absorbed by the liquid absorption layer 7, so that the detection probe 301 leaving the cleaning sleeve 5 is cleaned and the surface remains dry, so as to facilitate the cleaning of the detection probe 301, so that the detection probe 301 is always kept clean, and the validity of the detection result is guaranteed;

[0052] Compared with the prior art which requires moving the detection probe 301 into a cleaning station for cleaning and then moving it back to the detection station for testing, the reproductive medicine biochemical immunoassay detection equipment omits the action of changing stations while ensuring the cleaning effect, and has a faster repeated detection speed, which can speed up the detection efficiency. It also saves repeated positioning actions, avoids the deviations that may be caused by repeated positioning, improves the detection accuracy (positioning accuracy) of the detection probe 301 during the detection process, improves the detection effect, and has a better overall use effect.

[0053] Figure 4 It is shown that a waste liquid storage chamber 11 is fixed and connected to the lower end of the cleaning sleeve 5, and a pumping mechanism 10 for pumping out waste liquid in the waste liquid storage chamber 11 is installed on the outer side of the cleaning sleeve 5;

[0054] An adjustable linkage rod 9 is installed at the upper end of the liquid pressing plate 8 , and the adjustable linkage rod 9 is used to drive the liquid pressing plate 8 to rise and fall and enable the liquid pressing plate 8 to press the cleaning fluid in the volume chamber 502 into the wiping cotton ring 6 .

[0055] The waste liquid absorbed by the liquid absorbing layer 7 is collected by the waste liquid containing chamber 11, and then the waste liquid in the waste liquid containing chamber 11 is extracted by the pumping mechanism 10, so as to achieve the purpose of cleaning the waste liquid in real time, and ensure that the liquid absorbing layer 7 can absorb the waste liquid for a long time during use, thereby ensuring the effectiveness of cleaning;

[0056] The adjustable linkage rod 9 is used to drive the liquid pressure plate 8 to rise and fall, and the liquid pressure plate 8 forces the cleaning liquid in the mass chamber 502 into the wiping cotton ring 6. During use, the cleaning liquid can be injected into the wiping cotton ring 6, so that the used cleaning liquid can also flow down from the inner side of the wiping cotton ring 6 into the liquid absorption layer 7 and be absorbed, thereby ensuring that there is always clean and uncontaminated cleaning liquid in the wiping cotton ring 6, and the effectiveness of cleaning can also be ensured.

[0057] In this way, while ensuring the cleaning effect of the detection probe 301, the waste liquid after cleaning is automatically discharged, achieving effective and continuous cleaning, and improving the practicality of the reproductive medicine biochemical immunoassay detection equipment.

[0058] Figure 4 and Figure 8 The liquid pressure plate 8 is shown to include a fixed disk 801 and a soft plug sheet 803. The fixed disk 801 is located at the upper end of the soft plug sheet 803 and is fixedly connected to the lower end of the adjustable linkage rod 9. The fixed disk 801 is made of hard material and has a plurality of evenly distributed disk holes 802. The soft plug sheet 803 is made of flexible material, and the upper end of the inner circle of the soft plug sheet 803 is fixed to the lower end of the inner circle of the fixed disk 801, and the fixed disk 801 is separated from the outer circle of the soft plug sheet 803.

[0059] When the liquid pressing plate 8 rises with the adjustable linkage rod 9, the cleaning liquid in the mass chamber 502 is squeezed by the fixed disk 801 and moves from the upper end of the fixed disk 801 to the lower end of the fixed disk 801 through the disk hole 802. At this time, the soft plug sheet 803 is affected by the pressure of the cleaning liquid moving downward and bends downward to form an open gap, so that the cleaning liquid can move to the bottom of the soft plug sheet 803. Then, the liquid pressing plate 8 falls with the adjustable linkage rod 9. At this time, the soft plug sheet 803 is affected by the pressure of the cleaning liquid below and bends upward and The fixed disk 801 is attached and fixed so that the disk hole 802 is closed, and then the fixed disk 801 cooperates with the soft plug sheet 803 to force the cleaning liquid below the soft plug sheet 803 into the wiping cotton ring 6, and the excess cleaning liquid in the wiping cotton ring 6 will be pressed to flow out along the lower inner side of the wiping cotton ring 6 and downward into the liquid absorption layer 7, thereby achieving the purpose of adding new cleaning liquid to the wiping cotton ring 6, ensuring that the cleaning liquid of the wiping cotton ring 6 can be continuously replaced during multiple uses to keep the cleaning effect consistent.

[0060] Figure 7-Figure 8 The adjustable linkage rod 9 is shown to include:

[0061] Connecting sleeve 901, the lower end of the connecting sleeve 901 is fixed to the upper end of the fixing plate 801;

[0062] A linkage rod 902, the linkage rod 902 is slidably connected in the connecting sleeve 901, the upper end of the linkage rod 902 is fixed to the upper end of the detection probe 301 through a connecting piece and rises and falls synchronously with the detection probe 301;

[0063] A stopper is provided at the lower end of the linkage rod 902 to prevent the linkage rod 902 from being separated from the connecting sleeve 1 901;

[0064] The limiting member includes a limiting collar 904, the upper end of which is fixed with a second connecting sleeve 905 slidably sleeved on the linkage rod 902, and the upper end of the second connecting sleeve 905 slides through the top of the first connecting sleeve 901;

[0065] An adjusting ring 906 is fixed to the upper end of the second connecting sleeve 905, a threaded portion 903 is provided in the middle of the linkage rod 902, and an internal thread matching the threaded portion 903 is provided in the adjusting ring 906;

[0066] The limiting ring 904 is slidably mounted on the linkage rod 902 .

[0067] By setting the adjustable linkage rod 9, when the detection probe 301 rises, the linkage rod 902 is driven to rise accordingly through the connecting piece. After the linkage rod 902 rises to a certain distance, the limiting collar 904 abuts against the inner top wall of the connecting sleeve 1 901, and drives the connecting sleeve 1 901 to rise accordingly, so that the connecting sleeve 1 901 can drive the fixed plate 801 to rise. When the detection probe 301 descends, the detection probe 301 first drives the linkage rod 902 to descend. When the limiting collar 904 at the lower end of the linkage rod 902 descends to the lower end of the connecting sleeve 1 901, the fixed plate 801 and the connecting sleeve 1 901 are pushed to descend synchronously, thereby realizing the effect of using the detection probe 301 itself to drive the fixed plate 801 (i.e., the liquid pressure plate 8) to rise and fall, and realizing the purpose of pressing the cleaning liquid in the mass chamber 502 into the wiping cotton ring 6.

[0068] In addition, by rotating the adjustment ring 906, the position of the adjustment ring 906 on the linkage rod 902 can be adjusted, so that the adjustment ring 906 drives the limiting ring 904 to slide up and down on the linkage rod 902 through the connecting sleeve 2 905, thereby changing the height of the limiting ring 904, thereby changing the linkage rod 902 to rise and drive the connecting sleeve 1 901 to rise synchronously. The required stroke, thereby adjusting the rising height of the fixed plate 801, thereby changing the distance between the lower end of the soft plug 803 and the upper end of the wiping cotton ring 6 after the pressure plate 8 rises, that is, the capacity space for accommodating the cleaning liquid, thereby changing the total amount of cleaning liquid pressed into the wiping cotton ring 6 each time, so that the replacement amount of the cleaning liquid can be adjusted according to actual use needs to meet a variety of different cleaning needs, and the actual use effect is better.

[0069] It should be noted that the lower end of the inner wall of the mass chamber 502 is directly fixed to the inner side of the upper end of the wiping cotton ring 6, and the fixed plate 801 and the soft plug 803 are annular and are both arranged between the inner and outer walls of the mass chamber 502 (not shown in the figure, refer to Figure 4 and Figure 8 ) while forming a seal.

[0070] Figure 5 It is shown that a sewage outlet 504 is provided at the lower end of the cleaning sleeve 5, a sewage inlet 1101 connected to the sewage outlet 504 is provided at the upper end of the waste liquid storage chamber 11, and a first one-way structure 12 is installed in the sewage outlet 504 and the waste liquid storage chamber 11;

[0071] The first one-way structure 12 includes a first fixed rod 1201, a first spring 1202 and a first blocking piece 1203. The first fixed rod 1201 is horizontally arranged and its two ends are fixed to the two ends of the inner wall of the sewage outlet 504. The upper and lower ends of the first spring 1202 are fixed to the first fixed rod 1201 and 1023 respectively. The lower end of the first spring 1202 passes through the sewage inlet 1101 and is located in the waste liquid holding chamber 11. The first blocking piece 1203 is located in the waste liquid holding chamber 11 and its diameter is greater than the inner diameter of the sewage inlet 1101.

[0072] Under normal conditions, the first sealing piece 1203 is separated from the top wall of the waste liquid holding chamber 11 under the action of gravity of the waste water gathered at the lower end of the cleaning sleeve 5, so that the waste water can flow out from the sewage outlet 504 and enter the waste liquid holding chamber 11 through the sewage inlet 1101. After the sewage flows out, the first sealing piece 1203 rises under the elastic force of the first spring 1202 and fits on the top wall of the waste liquid holding chamber 11 to form a seal, so that the waste water entering the waste liquid holding chamber 11 will not flow back, thereby achieving the effect of collecting waste water and avoiding secondary pollution.

[0073] It should be further explained that an inclined surface inclined inwardly and outwardly is formed between the inner bottom wall of the lower end of the cleaning sleeve 5 and the sewage outlet 504 , so as to guide the waste water absorbed by the liquid absorption layer 7 into the sewage outlet 504 .

[0074] Figure 4 and Figure 6 The extraction mechanism 10 is shown to include:

[0075] A delivery pipe 1001, the lower end of which is fixed and connected to the waste liquid storage bin 11 through a connecting elbow 14, and a transfer hole 1005 connected to an external sewage pipe is provided on one side of the upper end of the delivery pipe 1001;

[0076] The piston rod 1002 is slidably connected to the delivery tube 1001 and the upper end of the piston rod 1002 slides through the upper end of the delivery tube 1001, and a seal is formed between the upper end of the piston rod 1002 and the upper end of the delivery tube 1001. The upper end of the piston rod 1002 is also fixed to the upper end of the detection probe 301 through a connector and rises and falls synchronously with the detection probe 301;

[0077] The piston 1003 is fixed to the lower end of the piston rod 1002. The circumference of the piston 1003 is interference fit with the inner wall of the delivery tube 1001. The piston 1003 is provided with a plurality of evenly distributed through holes 1004.

[0078] A second one-way structure 13 for preventing sewage backflow is installed in each of the plurality of through holes 1004;

[0079] The second unidirectional structure 13 includes a second fixed rod 1301, a second spring 1302 and a second blocking piece 1303. The second fixed rod 1301 is horizontally arranged and both ends are fixed to the inner wall of the through hole 1004. The lower end of the second spring 1302 is fixed to the upper end of the second fixed rod 1301. The upper end of the second spring 1302 passes through the through hole 1004 and is fixed to the lower end of the second blocking piece 1303. The diameter of the second blocking piece 1303 is larger than the inner diameter of the through hole 1004.

[0080] When the detection probe 301 is raised or lowered, the piston rod 1002 is driven to rise or fall synchronously. When the piston rod 1002 is lowered, the piston 1003 is driven to fall synchronously. When the piston 1003 is lowered, the waste liquid (or air, if there is no waste liquid in the delivery pipe 1001, then work is done on the air in the delivery pipe 1001) in the delivery pipe 1001 below the piston 1003 is squeezed. At this time, since the waste liquid storage chamber 11 is sealed under the action of the first blocking piece 1203, the water flow is transferred to the upper part of the piston 1003 through the through hole 1004 when it is pressurized, that is, the water flow squeezes the waste liquid in the delivery pipe 1001. The second sealing piece 1303 is pressed so that the second sealing piece 1303 is separated from the upper end of the through hole 1004 to form a channel. After that, the piston rod 1002 drives the piston 1003 to rise. At this time, the second sealing piece 1303 descends under the action of the water pressure and the elastic force of the second spring 1302 and fits with the upper end surface of the piston 1003 at the through hole 1004, closing the through hole 1004, causing the water flow at the upper end of the piston 1003 to rise, and finally be discharged to the external sewage pipe through the adapter hole 1005, completing the discharge of the waste liquid after cleaning, achieving the effect of automatically discharging the waste liquid, and being more convenient to use.

[0081] It should be further explained that there is a certain linkage (synchronous motion relationship) between the first unidirectional structure 12 and the second unidirectional structure 13. For example, when the piston 1003 descends to squeeze the waste liquid below, the waste liquid in the waste liquid holding chamber 11 is also squeezed, thereby squeezing the first blocking piece 1203, so that the first blocking piece 1203 is tightly attached to the top wall of the waste liquid holding chamber 11 to form a seal. At this time, the second blocking piece 1303 is separated from the upper end of the through hole 1004 to form a channel; and when the piston 1003 rises, the second blocking piece 1303 is The sealing piece 1303 seals the through hole 1004 so that the through hole 1004 is closed. At this time, negative pressure is formed at the lower end of the piston 1003, and the negative pressure area extends into the waste liquid holding chamber 11, so that the first sealing piece 1203 is also affected by the negative pressure and separated from the top wall of the waste liquid holding chamber 11, opening the channel formed by the sewage outlet 504 and the sewage inlet 1101, and further collecting and sucking the waste liquid adsorbed in the liquid absorption layer 7 into the waste liquid holding chamber 11, which has a complementary linkage effect and enhances the effect of the liquid absorption layer 7 in adsorbing waste liquid.

[0082] Figure 3 , Figure 4 , Figure 6 as well as Figure 7 It is shown that a probe seat 302 is fixed to the upper end of the detection probe 301, and the connecting part includes a mounting rod 303, one end of the mounting rod 303 is fixed to one side of the probe seat 302, and the lower end of the mounting rod 303 is respectively fixed to the upper end of the linkage rod 902 and the upper end of the piston rod 1002. Through the use of the probe seat 302 and the mounting rod 303, the detection probe 301 can drive the linkage rod 902 and the piston rod 1002 to move synchronously when moving, thereby achieving corresponding effects, such as pressing new cleaning liquid into the wiping cotton ring 6 or discharging the waste liquid accumulated in the waste liquid holding chamber 11.

[0083] In view of current practical needs, the above-mentioned implementation mode adopted in this application is not limited to the scope of protection. Various changes made within the knowledge scope of technical personnel in this field without departing from the concept of this application still fall within the scope of protection of the present invention.

Claims

1. A biochemical immunoassay device for reproductive medicine, comprising a test chamber and a test tube rack detachably mounted in the test chamber, a detector mounted on the upper end of the test chamber, the detector comprising a detection probe that can move up and down in the test chamber, and a drive shaft that drives the test tube rack to rotate through a linkage member is also mounted in the test chamber, characterized in that: A cleaning sleeve is fixed to the top wall of the detection chamber, a middle through hole is provided in the middle of the cleaning sleeve for the detection probe to pass through, a mass chamber filled with cleaning liquid is formed between the inner and outer side walls of the upper end of the cleaning sleeve, a wiping cotton ring is fixed to the outer wall of the cleaning sleeve, the wiping cotton ring is located below the mass chamber and is closably connected to the mass chamber through a liquid pressure plate, and a partition plate is formed at the lower end of the wiping cotton ring, and the lower end of the partition plate is fixed to the outer wall of the cleaning sleeve; A liquid absorbing layer is filled between the partition plate and the bottom wall of the cleaning sleeve, and a limiting membrane for limiting the liquid absorbing layer is arranged between the partition plate and the bottom wall of the cleaning sleeve, and the limiting membrane has good water permeability; The inner wall of the wiping cotton ring and the inner wall of the limiting membrane outside the liquid absorption layer have the same size and structure as the inner wall of the middle through hole; An adjustable linkage rod is installed at the upper end of the liquid pressure plate, and the adjustable linkage rod is used to drive the liquid pressure plate to rise and fall and enable the liquid pressure plate to press the cleaning fluid in the volume chamber into the wiping cotton ring.

2. A reproductive medicine biochemical immunoassay device according to claim 1, characterized in that: A waste liquid storage bin is fixed and connected to the lower end of the cleaning sleeve, and a pumping mechanism for pumping out waste liquid in the waste liquid storage bin is installed on the outer side of the cleaning sleeve.

3. A reproductive medicine biochemical immunoassay device according to claim 2, characterized in that: The liquid pressure plate includes a fixed disk and a soft plug sheet, wherein the fixed disk is located at the upper end of the soft plug sheet and is fixedly connected to the lower end of the adjustable linkage rod, the fixed disk is made of a hard material and is provided with a plurality of evenly distributed disk holes, the soft plug sheet is made of a flexible material, and the upper end of the inner circle of the soft plug sheet is fixed to the lower end of the inner circle of the fixed disk, and the fixed disk is separated from the outer circle of the soft plug sheet.

4. A reproductive medicine biochemical immunoassay device according to claim 3, characterized in that: The adjustable linkage rod comprises: A connecting sleeve 1, wherein a lower end of the connecting sleeve is fixed to an upper end of a fixing plate; A linkage rod, wherein the linkage rod is slidably connected in the connecting sleeve 1, and the upper end of the linkage rod is fixed to the upper end of the detection probe through a connecting piece and rises and falls synchronously with the detection probe; The lower end of the linkage rod is provided with a limiting piece to prevent the linkage rod from being separated from the connecting sleeve.

5. A reproductive medicine biochemical immunoassay device according to claim 4, characterized in that: The limiting member comprises a limiting collar, the upper end of which is fixed with a second connecting sleeve slidably sleeved on the linkage rod, and the upper end of the second connecting sleeve slidably penetrates the top of the first connecting sleeve; An adjusting ring is fixed at the upper end of the second connecting sleeve, a threaded portion is provided in the middle of the linkage rod, and an internal thread matching the threaded portion is provided in the adjusting ring; The limiting collar is slidably sleeved on the linkage rod.

6. A reproductive medicine biochemical immunoassay device according to claim 2, characterized in that: The cleaning sleeve has a drain port at the lower end, the waste liquid storage tank has a drain port at the upper end, and the drain port and the waste liquid storage tank are both provided with a first one-way structure. The first one-way structure includes a first fixed rod, a first spring and a first blocking piece. The first fixed rod is horizontally arranged and its two ends are fixed to the two ends of the inner wall of the sewage outlet. The upper and lower ends of the first spring are respectively fixed to the first fixed rod and the first spring. The lower end of the first spring passes through the sewage inlet and is located in the waste liquid holding bin. The first blocking piece is located in the waste liquid holding bin and its diameter is larger than the inner diameter of the sewage inlet.

7. A reproductive medicine biochemical immunoassay device according to claim 4, characterized in that: The extraction mechanism comprises: A delivery pipe, the lower end of which is fixed and connected to the waste liquid storage bin via a connecting elbow, and one side of the upper end of the delivery pipe is provided with a transfer hole connected to an external sewage pipe; A piston rod, wherein the piston rod is slidably connected to the inside of the delivery tube and the upper end of the piston rod slides through the upper end of the delivery tube, a seal is formed between the upper end of the piston rod and the upper end of the delivery tube, and the upper end of the piston rod is also fixed to the upper end of the detection probe through a connecting piece and rises and falls synchronously with the detection probe; A piston, wherein the piston is fixed to the lower end of the piston rod, the circumference of the piston is interference fit with the inner wall of the delivery pipe, and the piston is provided with a plurality of evenly distributed through holes; A second one-way structure for preventing sewage from flowing back is installed in each of the plurality of through holes.

8. A reproductive medicine biochemical immunoassay device according to claim 7, characterized in that: The second unidirectional structure includes a second fixing rod, a second spring and a second blocking piece. The second fixing rod is horizontally arranged and both ends are fixed to the inner wall of the through hole. The lower end of the second spring is fixed to the upper end of the second fixing rod. The upper end of the second spring passes through the through hole and is fixed to the lower end of the second blocking piece. The diameter of the second blocking piece is larger than the inner diameter of the through hole.

9. A reproductive medicine biochemical immunoassay device according to claim 7, characterized in that: A probe seat is fixed to the upper end of the detection probe, and the connecting piece includes a mounting rod, one end of which is fixed to one side of the probe seat, and the lower end of the mounting rod is respectively fixed to the upper end of the linkage rod and the upper end of the piston rod.

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