Equipment for building abdominal organ trauma model of small rodent

By designing equipment for trauma models of small rodent abdominal organs, including impact mechanisms and reinforcement mechanisms, the problem of unintuitiveness and difficulty in controlling the construction of experimental animal impact injury model equipment in the prior art is solved, and the experimental capability is achieved control and predictability of results.

CN119184899AActive Publication Date: 2024-12-27THE THIRD MEDICAL CENT OF THE CHINESE PEOPLES LIBERATION ARMY GENERAL HOSPITAL

Patent Information

Application Number
CN202411702189.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-26
Publication Date
2024-12-27
Estimated Expiration
2044-11-26

AI Technical Summary

Technical Problem

The construction of experimental animal impact injury models in the prior art lacks supporting equipment, resulting in unintuitive artificial fall-off methods, difficult to control their strength, and difficult to predict experimental results.

Method used

A device for the construction of trauma model of abdominal organs in small rodents is designed, including an impact mechanism and a reinforcement mechanism. The impact force is recorded and controlled through gears and scale marks of the impact mechanism. The reinforcement mechanism is fixed by elastic bands and Velcro hooks. animals, ensure the controllability and predictability of the experiment.

Benefits of technology

The controllability and data recording of animal impact experiments are achieved, which reduces the uncertainty of experimental results and improves the reliability and efficiency of experiments.

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Abstract

The invention provides equipment for building a small rodent abdominal organ trauma model, and belongs to the technical field of animal model building. Comprising a base table, an experiment table, two groups of vertical plates and transverse plates, an impact mechanism; the impact mechanism comprises a connecting rod which is movably arranged at the top of the transverse plate and extends to the bottom of the transverse plate, and scale marks are arranged on the surface of the connecting rod; the impact mechanism is arranged, before an experiment, a gear can be driven to be separated from a limiting clamping block but still engaged with clamping teeth by pulling a control rod, at the moment, a connecting rod can be driven to move downwards through the clamping teeth by rotating the gear, a bottom plate is driven to move downwards through movement of the connecting rod, and the compression force of a driving spring can be reduced; therefore, the impact force of the animal in the impact experiment is adjusted, the experimental data can be visually recorded by observing the scale marks, and the force applied by an operator in the impact experiment can be more effectively controlled through the cooperation of the parts.
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Description

Technical Field

[0001] The invention relates to the technical field of animal model construction, and more particularly to a device for constructing an abdominal organ trauma model of a small rodent. Background Art

[0002] Due to disasters, car accidents and other reasons, various types of impact injuries often occur frequently, such as liver impact injuries and craniocerebral impact injuries. In recent years, with the country's strong support for the construction of a comprehensive trauma emergency system, more and more medical experts have devoted themselves to the research of impact injuries. Rodents are the most diverse group of mammals, and this type of animal is often used as medical experimental animals.

[0003] At present, the construction of experimental animal impact injury models is mainly carried out by artificial beating due to the lack of supporting equipment. However, manual beating to produce impact injuries is relatively cruel, and the operation methods of different experimenters are different. The force applied by the operator during each impact experiment is also different, which makes the experimental results difficult to predict. In order to more intuitively record and more effectively control the force applied by the operator during the impact experiment to meet the needs of experimental research, we proposed a device for constructing abdominal organ trauma models of small rodents. Summary of the invention

[0004] In view of the problems in the prior art, the object of the present invention is to provide a device for constructing an abdominal organ trauma model of small rodents.

[0005] To solve the above problems, the present invention adopts the following technical solutions.

[0006] A device for constructing an abdominal organ trauma model of a small rodent, comprising a base and a laboratory table arranged on the top of the base, wherein vertical plates fixedly connected to the base are arranged on both sides of the laboratory table, and horizontal plates are fixedly connected to the tops of two groups of vertical plates; the device for constructing an abdominal organ trauma model of a small rodent also includes: an impact mechanism, which is used to perform impact experimental operations on animals and is connected to the horizontal plates; a reinforcement mechanism, which is used to reinforce the placement of animals and is connected to the laboratory table and the impact mechanism.

[0007] Optionally, the impact mechanism includes a connecting rod movably arranged on the top of the cross plate and extending to the bottom of the cross plate, the surface of the connecting rod is provided with scale lines, the outer wall of the connecting rod is provided with multiple groups of latch teeth at equal distances, the interior of the cross plate is provided with a telescopic slide groove extending to the top of the cross plate, the interior of the telescopic slide groove is movably provided with an inner slider, the top two ends of the inner slider are fixedly connected with mounting plates, control rods are movably provided inside and outside the two groups of mounting plates, the outer wall of the control rod is fixedly connected with a gear located between the two groups of mounting plates, and the gear is meshed with the multiple groups of latch teeth.

[0008] Optionally, the impact mechanism also includes a pressure spring sleeved on the outer wall of the control rod, the pressure spring is located between a group of the mounting plates and the gear, the outer wall of the lower end of the connecting rod is fixedly connected to a bottom plate, the bottom of the connecting rod is provided with an impact block, the impact block is connected to the connecting rod through a thread, the top of the bottom plate is provided with a driving spring that abuts against the cross plate, the inside of the telescopic slide groove is provided with a telescopic spring, the two ends of the telescopic spring are respectively abutted against the inner sliding block and the inner wall of the telescopic slide groove, and a limit block fixedly connected to the mounting plate is provided at the bottom away from the gear, and the limit block is engaged with the gear.

[0009] Optionally, the reinforcement mechanism includes transmission rods symmetrically fixedly connected to both sides of the base plate, an elastic band is symmetrically fixedly connected to one end of the top of the laboratory bench, and the tops of two groups of the elastic bands are provided with Velcro hook surfaces away from the laboratory bench, and the other end of the top of the laboratory bench is also symmetrically fixedly connected to a fixed base, and the tops of the two groups of the fixed bases are fixedly connected to connecting blocks, and the connecting blocks are located on the fixed base close to one end of the elastic band, and vertical plates are also symmetrically arranged on the top of the fixed base, and an auxiliary rod is arranged between the two groups of the vertical plates, and both sides of the auxiliary rod are fixedly connected to a rotating shaft extending to the inside of the vertical plate, and the auxiliary rod is rotatably connected to the vertical plate via the rotating shaft, and a driving groove is provided in the interior of one group of the rotating shafts close to the transmission rods, and a torsion spring is sleeved on the outer wall of the other group of the rotating shafts.

[0010] Optionally, the reinforcement mechanism also includes an upper transmission block arranged below the transmission rod, the outer wall of the upper end of the upper transmission block is fixedly connected to an upper driving rod extending to the inside of the driving slide groove, the outer wall of the lower end of the upper transmission block is provided with a lower sliding rod passing through the vertical plate, the interior of the vertical plate is provided with a through hole matching the outer diameter of the lower sliding rod, a lower transmission block fixedly connected to the fixed base is provided below the upper transmission block, and a protrusion is fixedly connected to the top of the auxiliary rod.

[0011] Optionally, a first inclined surface structure is provided on the top of the upper transmission block, and a second inclined surface structure is provided on one end of the lower transmission block close to the elastic band.

[0012] Optionally, an annular bevel groove is provided on one side of the inner wall of the driving slide groove, and the annular bevel groove is a spiral structure.

[0013] Optionally, a group of the rotating shafts and a group of the outer walls of the vertical plates are fixedly connected with stoppers, and both ends of the torsion spring are respectively against the two groups of stoppers.

[0014] Optionally, a T-shaped slider is fixedly connected to the bottom of the fixed base, and a T-shaped slot extending to the top of the laboratory bench is provided inside the laboratory bench, the T-shaped slot matches the overall structure of the T-shaped slider, and the fixed base is only arranged on the top of the laboratory bench through the T-shaped slot.

[0015] Optionally, avoidance grooves matching the two groups of transmission rods are provided inside the base, and the avoidance grooves are located below the transmission rods.

[0016] Compared with the prior art, the technical solution provided by the present invention has at least the following beneficial effects:

[0017] In the above scheme, by setting up the impact mechanism, we can pull the control rod to drive the gear to separate from the limit block but still keep it engaged with the card teeth before the experiment. At this time, rotating the gear can drive the connecting rod to move downward through the card teeth, and the movement of the connecting rod drives the bottom plate to move downward, which can reduce the compression force of the driving spring, thereby adjusting the impact force during the impact experiment on the animal, and by observing the scale line, the experimental data can be recorded intuitively. Through the cooperation between the above parts, the force applied by the operator during the impact experiment can be more effectively controlled to meet the needs of experimental research.

[0018] Through the reinforcement mechanism, during the impact experiment on the animal, the driving spring pushes the bottom plate to move downward. Before the impact block hits the animal, the bottom plate drives the two sets of transmission rods to move downward, so that the lower end of the transmission rod first contacts the upper transmission block and squeezes the first inclined surface structure, so that the upper transmission block drives the upper driving rod to insert into the inner wall of the driving slide groove and squeezes the annular inclined groove, so that the rotating shaft rotates, and the rotation of the rotating shaft drives the auxiliary rod to rotate. The rotation of the auxiliary rod drives the protrusion to rotate with the rotating shaft as the center of the circle, so that the protrusion is against the surface of the connection between the Velcro hook surface and the connecting block, thereby completing the connection reinforcement operation between the Velcro hook surface and the connecting block, which can prevent the animal from moving when hit, causing the Velcro hook surface and the connecting block to loosen, making the experiment unpredictable.

[0019] By setting a lower transmission block, as the transmission rod continues to move downward, the transmission rod squeezes the lower transmission block through the second inclined surface structure, causing the lower transmission block to move away from the elastic band, and driving the fixed base to move synchronously to stretch the elastic band, thereby tightening the elastic band to further fix the upper and lower limbs of the animal, thereby limiting the displacement of the animal during the impact process and affecting the experimental research data. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The accompanying drawings, which are incorporated herein and constitute a part of the specification, illustrate embodiments of the invention and, together with the description, further serve to explain the principles of the invention and to enable those skilled in the relevant art to make and use the invention.

[0021] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0022] Figure 2 It is a schematic diagram of the cross-section structure of the horizontal plate of the present invention;

[0023] Figure 3 It is a partial cross-sectional exploded view of the connecting rod and the bottom plate of the present invention;

[0024] Figure 4 It is an exploded view of the gear and the limit block of the present invention;

[0025] Figure 5 It is a structural schematic diagram of the reinforcement mechanism of the present invention;

[0026] Figure 6 For the present invention Figure 5 Enlarged view of point A in the middle;

[0027] Figure 7 It is a schematic diagram of the local structure of the reinforcement mechanism of the present invention;

[0028] Figure 8 It is a cross-sectional exploded view of the auxiliary rod of the present invention;

[0029] Fig. 9 It is a cross-sectional view of the rotating shaft of the present invention.

[0030] [Reference Signs]

[0031] 1. Base; 2. Vertical plate; 3. Horizontal plate; 4. Laboratory table; 5. Connecting rod; 6. Impact block; 7. Control rod; 8. Gear; 9. Clamping tooth; 10. Driving spring; 11. Bottom plate; 12. Transmission rod; 13. Slider; 14. Telescopic spring; 15. Telescopic slide; 16. Pressure spring; 17. Limiting block; 18. Elastic band; 19. Velcro hook; 20. Fixed base; 21. Auxiliary rod; 22. Bump; 23. Connecting block; 24. Torsion spring; 25. Vertical plate; 26. Upper transmission block; 27. Lower slide rod; 28. Upper driving rod; 29. ​​Rotating shaft; 30. Driving slide; 31. T-shaped slide; 32. Lower transmission block.

[0032] As shown in the figure, in order to clearly implement the structure of the embodiment of the present invention, specific structures and devices are marked in the figure, but this is only for illustrative purposes and is not intended to limit the present invention to the specific structure, device and environment. According to specific needs, ordinary technicians in this field can adjust or modify these devices and environments. DETAILED DESCRIPTION

[0033] The present invention is described in detail below in conjunction with the accompanying drawings and specific embodiments. At the same time, it is explained here that in order to make the embodiments more detailed, the following embodiments are the best and preferred embodiments, and those skilled in the art may also adopt other alternatives to implement some known technologies; and the accompanying drawings are only for more specific description of the embodiments, and are not intended to specifically limit the present invention.

[0034] It should be noted that the references to "one embodiment", "embodiment", "exemplary embodiments", "some embodiments" and the like in the specification indicate that the embodiments described may include specific features, structures or characteristics, but not every embodiment may include the specific features, structures or characteristics. In addition, when a specific feature, structure or characteristic is described in conjunction with an embodiment, it should be within the knowledge of a person skilled in the art to implement such feature, structure or characteristic in conjunction with other embodiments (whether or not explicitly described).

[0035] In general, a term can be understood, at least in part, from its use in context. For example, depending, at least in part, on the context, the term "one or more" as used herein can be used to describe any feature, structure, or characteristic in the singular sense, or can be used to describe a combination of features, structures, or characteristics in the plural sense. Additionally, the term "based on" can be understood as not necessarily intended to convey an exclusive set of factors, but can instead, depending, at least in part, on the context, allow for the presence of other factors that are not necessarily explicitly described.

[0036] It will be understood that the meanings of “on,” “over,” and “above” in the present invention should be interpreted in the broadest manner, so that “on” not only means “directly on” something, but also includes the meaning of being “on” something with intervening features or layers therebetween, and “on” or “over” not only means “on” or “above” something, but also includes the meaning of being “on” or “above” something with no intervening features or layers therebetween.

[0037] Additionally, spatially relative terms such as "under," "beneath," "lower," "above," "upper," and the like may be used herein for descriptive convenience to describe the relationship of one element or feature to another element or features, as shown in the accompanying drawings. Spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the accompanying drawings. The device may be oriented in other ways, and the spatially relative descriptors used herein may be similarly interpreted accordingly.

[0038] like Figures 1 to 9 As shown, an embodiment of the present invention provides a device for constructing an abdominal organ trauma model of a small rodent, comprising a base 1 and a laboratory table 4 arranged on the top of the base 1, wherein vertical plates 2 fixedly connected to the base 1 are arranged on both sides of the laboratory table 4, and horizontal plates 3 are fixedly connected to the tops of two groups of vertical plates 2; the device for constructing an abdominal organ trauma model of a small rodent also includes: an impact mechanism, which is used to perform a controllable impact experiment operation on the animal, and the impact mechanism is connected to the horizontal plate 3; a reinforcement mechanism, which is used to perform a reinforcement operation on the placement of the animal, and the reinforcement mechanism is connected to the laboratory table 4 and the impact mechanism.

[0039] The impact mechanism includes a connecting rod 5 movably arranged on the top of the cross plate 3 and extending to the bottom of the cross plate 3, the surface of the connecting rod 5 is provided with scale lines, the outer wall of the connecting rod 5 is equidistantly provided with multiple groups of latch teeth 9, the interior of the cross plate 3 is provided with a telescopic slide 15 extending to the top of the cross plate 3, the interior of the telescopic slide 15 is movably provided with an inner slider 13, the top two ends of the inner slider 13 are fixedly connected with mounting plates, the interior and exterior of the two groups of the mounting plates are movably provided with a control rod 7, the outer wall of the control rod 7 is fixedly connected with a gear 8 located between the two groups of the mounting plates, the gear 8 is meshed with the multiple groups of the latch teeth 9, and the impact mechanism also includes a sleeve connected to the control rod 7. The pressure spring 16 on the outer wall of the control rod 7 is located between a group of the mounting plates and the gear 8. The outer wall of the lower end of the connecting rod 5 is fixedly connected with a bottom plate 11. The bottom of the connecting rod 5 is provided with a collision block 6, and the collision block 6 is connected to the connecting rod 5 through a thread. The top of the bottom plate 11 is provided with a driving spring 10 that abuts against the cross plate 3. The inside of the telescopic slide 15 is provided with a telescopic spring 14, and the two ends of the telescopic spring 14 abut against the inner slider 13 and the inner wall of the telescopic slide 15 respectively. A limit block 17 fixedly connected to the mounting plate is provided at the bottom away from the gear 8, and the limit block 17 is engaged with the gear 8. The gear 8 is in a staggered meshing state with the latch teeth 9 and the limit block 17.

[0040] Before conducting trauma experiments on animals, the animals are first anesthetized and placed on the top of the experimental table 4 for fixing, so that the abdomen of the animals is facing the impact block 6, and then the control rod 7 is pulled to drive the gear 8 to move inside and on the top of the cross plate 3 through the mounting plate and the inner slider 13, so that the gear 8 is separated from the multiple groups of the latch teeth 9 to release the movement limit of the connecting rod 5. At this time, the reset action of the driving spring 10 pushes the bottom plate 11 to move downward, and the movement of the bottom plate 11 drives the connecting rod 5 to move downward, and the downward movement of the connecting rod 5 drives the impact block 6 to move downward to impact the abdomen of the animal, completing the impact experiment operation on the animal. Before performing the impact operation, the compression amount of the driving spring 10 can be recorded by observing the scale line on the surface of the connecting rod 5. According to Hooke's law: F= kx, where F is the elastic force of the spring, k is the spring coefficient, and x is the compression or elongation of the spring. When the spring coefficient k is constant, the greater the compression amount x, the greater the reset force F generated by the spring. The larger the value, the smaller the compression amount x is, and vice versa. The smaller the compression amount x is, the smaller the reset force F is. Before the experiment, we can pull the control rod 7 to drive the gear 8 to separate from the limit block 17 while still keeping it in mesh with the latch tooth 9. At this time, rotating the gear 8 can drive the connecting rod 5 to move downward through the latch tooth 9, and the bottom plate 11 is driven downward by the movement of the connecting rod 5, so as to reduce the compression force of the driving spring 10, thereby adjusting the impact force during the impact experiment on the animal, and by observing the scale line, the experimental data can be intuitively recorded. Through the cooperation between the above parts, the force applied by the operator during the impact experiment can be more effectively controlled to meet the needs of experimental research.

[0041] After completing the experimental operation, the control rod 7 is rotated in the reverse direction to drive the impact block 6 to move upward for reset, and then the gear 8 is pushed to re-engage with the limit block 17, and the reset force of the telescopic spring 14 is cooperated to push the inner slider 13 and the gear 8 arranged above the inner slider 13 to engage with the latch tooth 9. The stability of the misaligned meshing state between the gear 8, the latch tooth 9 and the limit block 17 can be maintained by the setting of the pressure spring 16, thereby preventing the gear 8 from rotating under the reset force of the transmission rod 12.

[0042] By setting a threaded connection between the impact block 6 and the connecting rod 5, the impact block 6 can be easily replaced. It should be noted that the specific shape of the lower end of the impact block 6 includes but is not limited to a circular structure. Impact blocks 6 of different shapes can be replaced according to research needs to complete the impact experiment.

[0043] like Figures 1 to 9As shown, the reinforcement mechanism includes a transmission rod 12 symmetrically fixedly connected to both sides of the bottom plate 11, an elastic band 18 is symmetrically fixedly connected to one end of the top of the experimental table 4, and the tops of the two groups of the elastic bands 18 are both provided with Velcro hook surfaces 19 away from the experimental table 4, and the other end of the top of the experimental table 4 is also symmetrically fixedly connected to a fixed base 20, and the tops of the two groups of the fixed bases 20 are both fixedly connected with connecting blocks 23, and the connecting blocks 23 are located at the fixed base 20 near one end of the elastic band 18, and the top of the fixed base 20 is also symmetrically provided with vertical plates 25, and an auxiliary rod 21 is provided between the two groups of the vertical plates 25, and both sides of the auxiliary rod 21 are fixedly connected with a rotating shaft 29 extending to the inside of the vertical plate 25, and the auxiliary rod 21 is rotatably connected to the vertical plate 25 through the rotating shaft 29, and a driving slide groove 30 is opened in the interior of one group of the rotating shafts 29 close to the transmission rod 12, and a torsion spring 24 is sleeved on the outer wall of the other group of the rotating shafts 29.

[0044] The reinforcement mechanism also includes an upper transmission block 26 arranged below the transmission rod 12, the outer wall of the upper end of the upper transmission block 26 is fixedly connected to an upper driving rod 28 extending into the driving slide groove 30, the outer wall of the lower end of the upper transmission block 26 is provided with a lower slide rod 27 penetrating the vertical plate 25, the interior of the vertical plate 25 is provided with a through hole matching the outer diameter of the lower slide rod 27, a lower transmission block 32 fixedly connected to the fixed base 20 is provided below the upper transmission block 26, the top of the auxiliary rod 21 is fixedly connected to the protrusion 22, the top of the upper transmission block 26 is provided with a first inclined surface structure, and the lower transmission block 32 A second inclined surface structure is provided near one end of the elastic band 18, an annular inclined groove is provided on one side of the inner wall of the driving slide 30, and the annular inclined groove is in a spiral structure. A set of the rotating shafts 29 and a set of the outer walls of the vertical plates 25 are fixedly connected with blocks, and the two ends of the torsion spring 24 are respectively against the two sets of the blocks. A T-shaped slider 31 is fixedly connected to the bottom of the fixed base 20, and a T-shaped slide extending to the top of the experimental table 4 is provided inside the experimental table 4. The T-shaped slide matches the overall structure of the T-shaped slider 31, and the fixed base 20 is only provided on the top of the experimental table 4 through the T-shaped slide. The top of the connecting block 23 is provided with a Velcro surface.

[0045] Before conducting an impact test on an animal, the anesthetized animal is first placed on the top of the experimental table 4, and the animal's body position is adjusted so that the animal's abdomen corresponds to the impact block 6, and then the two groups of the elastic bands 18 are pulled respectively to make the two groups of Velcro hook surfaces 19 fit with the Velcro fur surfaces on the surfaces of the two groups of the connecting blocks 23 respectively to press the upper and lower limbs of the animal, complete the pre-fixation of the animal's body position, and then conduct an impact test on the animal. In this process, the driving spring 10 pushes the bottom plate 11 to move downward. Before the impact block 6 hits the animal, the bottom plate 11 drives the two groups of the transmission rods 12 to move downward, so that the lower ends of the transmission rods 12 first contact the upper transmission block 26, and The first inclined surface structure is squeezed so that the upper transmission block 26 drives the upper drive rod 28 to insert into the inner wall of the drive slide groove 30, and squeezes the annular inclined groove, so that the rotating shaft 29 rotates. The rotation of the rotating shaft 29 drives the auxiliary rod 21 to rotate. The rotation of the auxiliary rod 21 drives the protrusion 22 to rotate with the rotating shaft 29 as the center, so that the protrusion 22 is against the surface of the connection between the Velcro hook surface 19 and the connecting block 23, thereby completing the connection reinforcement operation between the Velcro hook surface 19 and the connecting block 23, which can prevent the animal from moving when hit, causing the Velcro hook surface 19 and the connecting block 23 to loosen, making the experiment unpredictable.

[0046] As the transmission rod 12 continues to move downward, the transmission rod 12 squeezes the lower transmission block 32 through the second inclined structure, causing the lower transmission block 32 to move away from the elastic band 18, and drives the fixed base 20 to move synchronously to stretch the elastic band 18, thereby tightening the elastic band 18 to further fix the upper and lower limbs of the animal, thereby limiting the displacement of the animal during the impact and affecting the experimental research data.

[0047] After completing the impact operation on the animal and resetting the impact block 6, the resetting force of the torsion spring 24 can drive the auxiliary rod 21 to rotate in the opposite direction through the baffle to drive the protrusion 22 to separate from the elastic band 18, thereby releasing the reinforcement operation between the elastic band 18 and the connecting block 23, thereby facilitating the operator to clean the surface of the experimental table 4.

[0048] like Figure 1 As shown, the interior of the base 1 is provided with avoidance grooves matching the two groups of the transmission rods 12, and the avoidance grooves are located below the transmission rods 12; this structural arrangement allows the transmission rods 12 to move.

[0049] The working process of the technical solution provided by the present invention is as follows:

[0050] First, before conducting an impact experiment on an animal, place the anesthetized animal on the top of the experimental table 4, and adjust the animal's body position so that the animal's abdomen corresponds to the impact block 6, then pull the two sets of elastic bands 18 respectively, so that the two sets of Velcro hook surfaces 19 are respectively fitted with the Velcro fur surfaces on the surfaces of the two sets of connecting blocks 23, to press the upper and lower limbs of the animal, complete the pre-fixation of the animal's body position, and then conduct an impact experiment on the animal, by pulling the control rod 7, the control rod 7 drives the gear 8 to move inside and on the top of the cross plate 3 through the mounting plate and the inner slider 13, so that the gear 8 is separated from the multiple sets of latch teeth 9, to release the movement limit of the connecting rod 5, at this time, the reset effect of the driving spring 10 pushes the bottom plate 11 to move downward, the movement of the bottom plate 11 drives the connecting rod 5 to move downward, and the connecting rod 5 moves downward Drive the impact block 6 to move downward to impact the animal's abdomen to complete the impact experiment operation on the animal. Before performing the impact operation, the compression amount of the driving spring 10 can be recorded by observing the scale lines on the surface of the connecting rod 5. Before the experiment, we can pull the control rod 7 to drive the gear 8 to separate from the limit block 17 while still keeping it engaged with the latch tooth 9. At this time, rotating the gear 8 can drive the connecting rod 5 to move downward through the latch tooth 9, and the bottom plate 11 is driven downward by the movement of the connecting rod 5, which can reduce the compression force of the driving spring 10, thereby adjusting the impact force during the impact experiment on the animal. In conjunction with observing the scale lines, the experimental data can be intuitively recorded. Through the cooperation between the above parts, the force applied by the operator during the impact experiment can be more effectively controlled to meet the needs of experimental research.

[0051] Then in this process, the driving spring 10 pushes the bottom plate 11 to move downward. Before the impact block 6 hits the animal, the bottom plate 11 drives the two sets of transmission rods 12 to move downward, so that the lower end of the transmission rod 12 first contacts the upper transmission block 26 and squeezes the first inclined surface structure, so that the upper transmission block 26 drives the upper driving rod 28 to insert into the inner wall of the driving slide groove 30, and squeezes the annular inclined groove, so that the rotating shaft 29 rotates, and the rotation of the rotating shaft 29 drives the auxiliary rod 21 to rotate. The rotation of the auxiliary rod 21 drives the protrusion 22 to rotate with the rotating shaft 29 as the center, so that the protrusion 22 is against the surface of the connection between the Velcro hook surface 19 and the connecting block 23, thereby completing the connection reinforcement operation between the Velcro hook surface 19 and the connecting block 23, which can prevent the animal from moving when hit, causing the Velcro hook surface 19 and the connecting block 23 to loosen, making the experiment unpredictable.

[0052] Then, as the transmission rod 12 continues to move downward, the transmission rod 12 squeezes the lower transmission block 32 through the second inclined structure, causing the lower transmission block 32 to move away from the elastic band 18, and drives the fixed base 20 to move synchronously to stretch the elastic band 18, thereby tightening the elastic band 18 to further fix the upper and lower limbs of the animal, thereby limiting the displacement of the animal during the impact and affecting the experimental research data.

[0053] By pulling the control rod 7, the control rod 7 drives the gear 8 to move inside and on the top of the cross plate 3 through the mounting plate and the inner slider 13, so that the gear 8 is separated from the multiple groups of latch teeth 9 to release the movement limit of the connecting rod 5. At this time, the restoring effect of the driving spring 10 pushes the bottom plate 11 to move downward, and the movement of the bottom plate 11 drives the connecting rod 5 to move downward. The downward movement of the connecting rod 5 drives the impact block 6 to move downward to impact the abdomen of the animal, completing the impact experiment operation on the animal. Before performing the impact operation, the compression amount of the driving spring 10 can be recorded by observing the scale line on the surface of the connecting rod 5. According to Hooke's law: F = kx, where F is the elastic force of the spring, k is the spring coefficient, and x is the compression or elongation of the spring. When the spring coefficient k is constant, the greater the compression amount x, the greater the reset force F generated by the spring. Conversely, the smaller the compression amount x, the greater the reset force F The smaller it is, before the experiment, we can pull the control rod 7 to drive the gear 8 to separate from the limit block 17 but still keep it in mesh with the latch tooth 9. At this time, rotating the gear 8 can drive the connecting rod 5 to move downward through the latch tooth 9, and the movement of the connecting rod 5 drives the bottom plate 11 to move downward, which can reduce the compression force of the driving spring 10, thereby adjusting the impact force during the impact experiment on the animal, and observing the scale line to intuitively record the experimental data. Through the cooperation between the above parts, the force applied by the operator during the impact experiment can be more effectively controlled to meet the needs of experimental research.

[0054] The present invention covers any substitution, modification, equivalent method and scheme made on the essence and scope of the present invention. In order to make the public have a thorough understanding of the present invention, specific details are described in detail in the preferred embodiments of the present invention, but those skilled in the art can fully understand the present invention without the description of these details. In addition, in order to avoid unnecessary confusion about the essence of the present invention, well-known methods, processes, procedures, components and circuits are not described in detail.

[0055] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A device for constructing a small rodent abdominal organ trauma model, comprising a base and a laboratory table arranged on the top of the base, vertical plates fixedly connected to the base are arranged on both sides of the laboratory table, and horizontal plates are fixedly connected to the tops of two groups of vertical plates, characterized in that: The device for constructing a small rodent abdominal organ trauma model also includes: An impact mechanism, which is used to perform an impact experiment on an animal and is connected to the horizontal plate; A reinforcement mechanism is used to reinforce the placement of the animal, and the reinforcement mechanism is connected to the experimental table and the impact mechanism.

2. The device for constructing an abdominal organ trauma model of a small rodent according to claim 1, characterized in that: The impact mechanism includes a connecting rod movably arranged on the top of the cross plate and extending to the bottom of the cross plate, the surface of the connecting rod is provided with scale lines, the outer wall of the connecting rod is provided with multiple groups of latch teeth at equal distances, the interior of the cross plate is provided with a telescopic slide groove extending to the top of the cross plate, the interior of the telescopic slide groove is movably provided with an inner slider, the top two ends of the inner slider are fixedly connected with mounting plates, control rods are movably provided inside and outside the two groups of mounting plates, the outer wall of the control rod is fixedly connected with a gear located between the two groups of mounting plates, and the gear is meshed with the multiple groups of latch teeth.

3. The device for constructing an abdominal organ trauma model of a small rodent according to claim 2, characterized in that: The impact mechanism also includes a pressure spring sleeved on the outer wall of the control rod, the pressure spring is located between a group of the mounting plates and the gear, the outer wall of the lower end of the connecting rod is fixedly connected to a bottom plate, the bottom of the connecting rod is provided with an impact block, the impact block is connected to the connecting rod through a thread, the top of the bottom plate is provided with a driving spring that abuts against the cross plate, the inside of the telescopic slide groove is provided with a telescopic spring, the two ends of the telescopic spring are respectively abutted against the inner sliding block and the inner wall of the telescopic slide groove, and a limit block fixedly connected to the mounting plate is provided at the bottom away from the gear, and the limit block and the gear are engaged with each other.

4. The device for constructing an abdominal organ trauma model of a small rodent according to claim 3, characterized in that: The reinforcement mechanism includes transmission rods symmetrically fixedly connected to both sides of the bottom plate, an elastic band is symmetrically fixedly connected to one end of the top of the laboratory bench, and the tops of two groups of the elastic bands are provided with Velcro hook surfaces away from the laboratory bench, and the other end of the top of the laboratory bench is also symmetrically fixedly connected to a fixed base, and the tops of the two groups of the fixed bases are fixedly connected to connecting blocks, and the connecting blocks are located on the fixed base near one end of the elastic band, and vertical plates are symmetrically arranged on the top of the fixed base, and an auxiliary rod is arranged between the two groups of the vertical plates, and both sides of the auxiliary rod are fixedly connected to a rotating shaft extending to the inside of the vertical plate, and the auxiliary rod is rotatably connected to the vertical plate through the rotating shaft, and a driving groove is opened in the interior of the rotating shaft of one group close to the transmission rod, and a torsion spring is sleeved on the outer wall of the other group of the rotating shafts.

5. The device for constructing an abdominal organ trauma model of a small rodent according to claim 4, characterized in that: The reinforcement mechanism also includes an upper transmission block arranged below the transmission rod, the outer wall of the upper end of the upper transmission block is fixedly connected to the upper driving rod extending to the inside of the driving slide groove, the outer wall of the lower end of the upper transmission block is provided with a lower sliding rod passing through the vertical plate, the interior of the vertical plate is provided with a through hole matching the outer diameter of the lower sliding rod, a lower transmission block fixedly connected to the fixed base is provided below the upper transmission block, and a protrusion is fixedly connected to the top of the auxiliary rod.

6. The device for constructing an abdominal organ trauma model of a small rodent according to claim 5, characterized in that: A first inclined surface structure is arranged on the top of the upper transmission block, and a second inclined surface structure is arranged on one end of the lower transmission block close to the elastic band.

7. The device for constructing an abdominal organ trauma model of a small rodent according to claim 4, characterized in that: An annular bevel groove is arranged on one side of the inner wall of the driving slide groove, and the annular bevel groove is in a spiral structure.

8. The device for constructing an abdominal organ trauma model of a small rodent according to claim 4, characterized in that: The outer walls of one group of the rotating shafts and one group of the vertical plates are fixedly connected with stoppers, and the two ends of the torsion spring are respectively against the two groups of stoppers.

9. The device for constructing an abdominal organ trauma model of a small rodent according to claim 5, characterized in that: A T-shaped slider is fixedly connected to the bottom of the fixed base, and a T-shaped slot extending to the top of the laboratory bench is arranged inside the laboratory bench. The T-shaped slot matches the overall structure of the T-shaped slider, and the fixed base is movably arranged on the top of the laboratory bench through the T-shaped slot.

10. The device for constructing an abdominal organ trauma model of a small rodent according to claim 4, characterized in that: The interior of the base is provided with avoidance grooves matching the two groups of transmission rods, and the avoidance grooves are located below the transmission rods.

Citation Information

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