Hyperthermal perfusion catheter and hyperthermal perfusion system

Abstract

The invention provides a hyperthermic perfusion catheter which comprises a catheter body, the catheter body is provided with an injection end suitable for injecting liquid medicine and an output end suitable for guiding the medicine to an affected part, and a first channel is formed between the injection end and the output end; the heat insulation part is arranged outside the pipe body in a sleeving manner, covers at least one part of the axial direction of the pipe body, and has a first compressed state and a second expanded state; wherein the heat insulation part in the second state is suitable for isolating at least one part of heat of the medicine from being dissipated to the part outside the affected part. The invention further provides a hyperthermia perfusion system. The hyperthermia perfusion system comprises the hyperthermia perfusion catheter. The control device is in communication connection with the heating device and the temperature sensing device and is configured to adjust the heating temperature of the heating device according to the medicine temperature fed back by the temperature sensing device; and the drug delivery device is in communication connection with the control device and is suitable for injecting drugs into the hyperthermia perfusion catheter.

Description

Technical Field

[0001] The present disclosure relates to the technical field of perfusion catheters, and in particular to a thermal perfusion catheter and a thermal perfusion system. Background Art

[0002] In the field of tumor treatment, minimally invasive technology has made significant progress, among which catheter intervention technology is an important treatment method. By introducing a catheter into the patient's body, local chemotherapy drug perfusion to the tumor area or chemotherapy embolization of the blood vessels supplying the tumor can be achieved, thereby improving the efficacy of chemotherapy while greatly reducing the patient's discomfort and pain. In addition, given the high sensitivity of tumor cells to temperature changes, using thermal effects to destroy tumor cells has also become an effective treatment strategy.

[0003] However, the current perfusion catheter has certain limitations when implementing treatment. The catheter needs to go through a long path to reach the tumor site. During this process, when the heated chemotherapy drugs are transported to the tumor area through the catheter, their heat is easily dissipated to the surrounding tissues during the transmission process, causing the temperature of the drugs at the catheter outlet to be close to the normal body temperature of the human body, affecting the treatment effect; at the same time, if the drug temperature is too high, it may cause damage to the tissues around the catheter. The existence of these problems limits the effect of precision treatment of chemotherapy drugs and urgently needs optimization and innovation. Summary of the invention

[0004] In view of this, the present disclosure provides a thermal perfusion catheter, in which a heat insulating portion is arranged outside the tube body to prevent the heat from being dissipated or damaging surrounding tissues during the transmission process when the heated chemotherapy drugs are delivered to the tumor area through the catheter.

[0005] An embodiment of the present disclosure provides a thermal perfusion catheter, comprising a tube body, having an injection end suitable for injecting liquid drugs, and an output end suitable for guiding the above-mentioned drugs to an affected area, a first channel being formed between the above-mentioned injection end and the above-mentioned output end; and a heat-insulating portion, which is sleeved on the outside of the above-mentioned tube body and covers at least a part of the axial direction of the above-mentioned tube body, and has a first compressed state and a second expanded state; wherein the heat-insulating portion in the above-mentioned second state is suitable for isolating at least a part of the above-mentioned drugs from heat dissipation or damaging the part other than the above-mentioned affected area.

[0006] According to some embodiments of the present disclosure, the above-mentioned insulation part includes a first air injection port, which is suitable for inflating and deflating the above-mentioned insulation part to switch the above-mentioned insulation part between the first state and the second state.

[0007] According to some embodiments of the present disclosure, the thermal insulation portion is configured in a spiral shape, surrounding the outside of the tube body along an extension direction of the first channel.

[0008] According to some embodiments of the present disclosure, the above-mentioned hot perfusion catheter also includes a check portion, which is sleeved on the outside of the above-mentioned output end and has a compressed third state and an expanded fourth state; the above-mentioned check portion includes a second air injection port, which is suitable for inflating and deflating the above-mentioned check portion, so that the above-mentioned check portion can be switched between the third state and the fourth state; wherein the check portion in the above-mentioned fourth state is suitable for blocking the backflow of the above-mentioned drug in the above-mentioned affected area.

[0009] According to some embodiments of the present disclosure, the thermal perfusion catheter further includes a heating device installed on the tube body and adapted to heat the drug flowing through the first channel.

[0010] According to some embodiments of the present disclosure, the thermal perfusion catheter further includes a temperature sensing device adapted to monitor the temperature of the heating device and / or the heated drug.

[0011] According to some embodiments of the present disclosure, the heating device and the temperature sensing device are installed on the tube body outside the heat insulation portion.

[0012] According to some embodiments of the present disclosure, the heating device and the temperature sensing device are installed between the heat insulation portion and the tube body.

[0013] According to some embodiments of the present disclosure, the temperature sensing device is constructed in a cylindrical shape and is sleeved on the circumference of the tube body; the heating device covers the outside of the temperature sensing device.

[0014] An embodiment of the present disclosure also provides a thermal perfusion system, comprising the above-mentioned thermal perfusion catheter; a control device, which is communicatively connected to the above-mentioned heating device and the above-mentioned temperature sensing device, and is configured to adjust the heating temperature of the above-mentioned heating device according to the drug temperature feedback from the above-mentioned temperature sensing device; and a drug delivery device, which is communicatively connected to the above-mentioned control device, and is suitable for perfusing the above-mentioned drug into the inside of the above-mentioned thermal perfusion catheter.

[0015] According to a thermal perfusion catheter provided by the present disclosure, a thermal insulation portion is arranged on the outside of a tube body suitable for injecting drugs, and the thermal insulation portion has a compressed first state and an expanded second state. The thermal insulation portion in the second state can effectively separate external tissues from the drugs inside the tube body, preventing the heated drugs from dissipating heat or damaging external tissues during transportation, thereby ensuring the temperature of the drugs when they reach the affected area. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] The above and other objects, features and advantages of the present disclosure will become more apparent through the following description of the embodiments of the present disclosure with reference to the accompanying drawings, in which:

[0017] Figure 1 Schematically shows a front view of a thermal perfusion catheter in a first state according to an embodiment of the present disclosure;

[0018] Figure 2 A schematic diagram shows a structural stereogram of a thermal perfusion catheter in a second state according to an embodiment of the present disclosure;

[0019] Figure 3 A schematic cross-sectional view of a thermal perfusion catheter in a first state according to an embodiment of the present disclosure is shown;

[0020] Figure 4 A schematic cross-sectional view of a thermal perfusion catheter in a second state according to an embodiment of the present disclosure is shown;

[0021] Figure 5 Schematically showing a front view of a thermal perfusion catheter in a second state according to another embodiment of the present disclosure;

[0022] Figure 6 Schematically showing a front view of a thermal perfusion catheter in a first state according to another embodiment of the present disclosure;

[0023] Figure 7 Schematically shows a cross-sectional schematic diagram of a thermal perfusion catheter in a first state according to another embodiment of the present disclosure;

[0024] Figure 8 Schematically showing a front view of a thermal perfusion catheter in a second state according to another embodiment of the present disclosure;

[0025] Fig. 9 Schematically shows a cross-sectional schematic diagram of a thermal perfusion catheter in a second state according to another embodiment of the present disclosure;

[0026] Fig.10 The structural diagram of a heating device according to an embodiment of the present disclosure is schematically shown;

[0027] Fig.11 A schematic structural diagram of a heating device according to another embodiment of the present disclosure is shown;

[0028] Fig.12 A schematic cross-sectional view of a heating device inside a thermal perfusion catheter according to another embodiment of the present disclosure is shown;

[0029] Fig.13 A front view schematically shows a heating device according to another embodiment of the present disclosure;

[0030] Fig.14 A front view schematically shows a heating device according to another embodiment of the present disclosure;

[0031] Fig.15 Schematically showing a front view of a thermal perfusion catheter in a first state according to yet another embodiment of the present disclosure;

[0032] Fig.16Schematically showing a front view of a thermal perfusion catheter in a second state according to yet another embodiment of the present disclosure;

[0033] Fig.17 A schematic diagram of a thermal perfusion system according to an embodiment of the present disclosure is schematically shown.

[0034] In the drawings, the meanings of the reference numerals are as follows:

[0035] 1. Pipe body;

[0036] 11. Output terminal;

[0037] 12. Injection end;

[0038] 13. First channel;

[0039] 2. Insulation part;

[0040] 21. First gas injection port;

[0041] 3. Backstop;

[0042] 31. Second gas injection port;

[0043] 4. Heating device;

[0044] 41. Heating coil;

[0045] 42. Heating coil lead;

[0046] 43. Metal conduits; and

[0047] 5. Temperature sensing device.

[0048] 6. Control device;

[0049] 61. Controller;

[0050] 62. Control screen;

[0051] 63. Quick adjustment knob;

[0052] 7. Drug delivery device;

[0053] 71. Executing motor; and

[0054] 72. Monitoring components. DETAILED DESCRIPTION

[0055] In order to make the objectives, technical solutions and advantages of the present disclosure more clearly understood, the present disclosure is further described in detail below in combination with specific embodiments and with reference to the accompanying drawings.

[0056] The terms used herein are only for describing specific embodiments and are not intended to limit the present disclosure. The terms "comprise", "include", etc. used herein indicate the existence of the features, steps, operations and / or components, but do not exclude the existence or addition of one or more other features, steps, operations or components.

[0057] All terms used herein, including technical and scientific terms, have the meanings commonly understood by those skilled in the art, unless otherwise defined. It should be noted that the terms used herein should be interpreted as having a meaning consistent with the context of this specification, and should not be interpreted in an idealized or overly rigid manner.

[0058] When using expressions such as "at least one of A, B, and C, etc.", it should generally be interpreted as the meaning of the expression generally understood by those skilled in the art. For example, "a system having at least one of A, B, and C" should include but not be limited to a system having A alone, B alone, C alone, A and B, A and C, B and C, and / or A, B, C, etc. When using expressions such as "at least one of A, B, or C, etc.", it should generally be interpreted as the meaning of the expression generally understood by those skilled in the art. For example, "a system having at least one of A, B, or C" should include but not be limited to a system having A alone, B alone, C alone, A and B, A and C, B and C, and / or A, B, C, etc.

[0059] Figure 1 Schematically shows a front view of a thermal perfusion catheter in a first state according to an embodiment of the present disclosure; Figure 2 A cross-sectional schematic diagram of a thermal perfusion catheter in a first state according to an embodiment of the present disclosure is schematically shown.

[0060] According to an embodiment of the present disclosure, a thermal perfusion catheter is provided, such as Figure 1 and Figure 2 As shown, it includes: a tube body 1, having an injection end 12 suitable for injecting liquid drugs, and an output end 11 suitable for guiding the drugs to the affected area, and a first channel 13 is formed between the injection end 12 and the output end 11; and a heat insulating portion 2, which is sleeved on the outside of the tube body 1 and covers at least a part of the axial direction of the tube body 1, and has a first compressed state and a second expanded state; wherein the heat insulating portion 2 in the second state is suitable for isolating at least a part of the drug from heat dissipation or damage to the part other than the affected area.

[0061] According to the above-mentioned setting method, by setting an insulating part 2 on the outside of the tube body 1 suitable for injecting drugs, the insulating part 2 has a compressed first state and an expanded second state. The insulating part 2 in the second state can effectively separate the external tissue and the drug inside the tube body 1, preventing the heated drug from dissipating heat or damaging external tissue during transportation, thereby ensuring the temperature of the drug when it reaches the affected area.

[0062] In an illustrative embodiment, the heat insulating portion 2 covers the portion of the tube body 1 where the axis of the tube body 1 contacts tissues other than the affected area.

[0063] According to the above-mentioned configuration, the heat insulating portion 2 can effectively prevent the medicine inside the tube body 1 from being thermally dissipated or damaging tissues other than the affected area before being infused into the affected area.

[0064] In an illustrative embodiment, the output end 11 is configured to be tapered along the extension direction of the tube body 1 .

[0065] According to the above-mentioned setting method, the tapered output end 11 is conducive to reducing the resistance of the surrounding tissue to the end of the tube body 1 when the output end 11 of the tube body 1 reaches the affected area, so that the tube body 1 can safely and quickly reach the affected area for hot perfusion treatment of chemotherapy drugs.

[0066] Figure 3 A schematic diagram shows a structural stereogram of a thermal perfusion catheter in a second state according to an embodiment of the present disclosure; Figure 4 A cross-sectional diagram of a thermal perfusion catheter in a second state according to an embodiment of the present disclosure is schematically shown.

[0067] In an illustrative embodiment, the thermal insulation portion 2 includes a first gas injection port 21, which is suitable for inflating and deflating gas into the thermal insulation portion 2, so that the thermal insulation portion 2 is switched between the first state and the second state.

[0068] According to the above-mentioned setting method, the first gas injection port 21 is provided in the insulation part 2, so that the insulation part 2 has a first unaerated state and a second inflated state. In the first state, there is no gas inside the insulation part 2, which is convenient for the movement of the output end 11 of the tube body 1 in the process of reaching the affected part. In the second state, the insulation part 2 forms a gas interlayer between the external tissue and the tube body, which can effectively prevent the medicine inside the tube body 1 from heat dissipation or damage to tissues other than the affected part before being injected into the affected part.

[0069] In an illustrative embodiment, Figure 1 As shown, a first accommodating groove for accommodating the heat insulating portion 2 is provided on the side surface of the tube body 1 , so that the diameter of the heat insulating portion 2 in the first state is less than or equal to the diameter of the tube body 1 .

[0070] According to the above-mentioned setting method, a first receiving groove is set on the tube body 1, so that the diameter of the insulation part 2 in the first state is less than or equal to the diameter of the tube body 1, which is conducive to the movement of the output end 11 of the tube body 1 in the surrounding tissue when reaching the affected area.

[0071] In an illustrative embodiment, Figure 3 As shown, the diameter of the heat insulating portion 2 in the second state is larger than the diameter of the tube body 1, so that the gas interlayer formed inside can effectively prevent the heat dissipation of the drug or damage to the surrounding tissues.

[0072] Figure 5 A front view of a thermal perfusion catheter in a second state according to another embodiment of the present disclosure is schematically shown.

[0073] In an illustrative embodiment, Figure 5 As shown, the heat insulating portion 2 is configured in a spiral shape and surrounds the outside of the tube body 1 along the extending direction of the first channel 13 .

[0074] According to the above-mentioned arrangement, during the perfusion process, if the tube body 1 is in a bent state, the heat insulating portion 2 is configured in a spiral shape, which is beneficial for the heat insulating portion 2 in the second state to maintain the internal gas interlayer, thereby avoiding the surface of the heat insulating portion 2 being restricted by tension and / or extrusion force due to the bending, causing part of the gas interlayer to disappear, resulting in heat dissipation of the drug or damage to surrounding tissues.

[0075] Figure 6 Schematically showing a front view of a thermal perfusion catheter in a first state according to another embodiment of the present disclosure; Figure 7 Schematically shows a cross-sectional schematic diagram of a thermal perfusion catheter in a first state according to another embodiment of the present disclosure; Figure 8 Schematically showing a front view of a thermal perfusion catheter in a second state according to another embodiment of the present disclosure; Fig. 9 A cross-sectional schematic diagram of a thermal perfusion catheter in a second state according to yet another embodiment of the present disclosure is schematically shown.

[0076] In an illustrative embodiment, Figures 6 to 9 As shown, it also includes a check portion 3, which is sleeved on the outside of the output end 11 and has a compressed third state and an expanded fourth state; the check portion 3 includes a second air injection port 31, which is suitable for inflating and deflating the check portion 3, so that the check portion 3 can switch between the third state and the fourth state; wherein, the check portion 3 in the fourth state is suitable for blocking the backflow of drugs from the affected area.

[0077] In detail, the check portion 3 in the second state abuts against the inner wall of the surrounding tissue.

[0078] According to the above-mentioned setting mode, the check portion 3 is provided at the output end 12 of the tube body 1, which can effectively prevent the drug from flowing back from the affected area in the second state, ensure the unidirectional flow of the drug during the drug perfusion process, and improve the reliability and safety of hot perfusion.

[0079] In an illustrative embodiment, Figure 8 and Fig. 9 As shown, when the heat insulating portion 2 and the check portion 3 are provided on the tube body 1 at the same time, the diameter of the check portion 3 in the second state is greater than the diameter of the heat insulating portion 2 in the second state.

[0080] In an illustrative embodiment, Figure 7 As shown, a second receiving groove for receiving the non-return portion 3 is provided on the side surface of the tube body 1 , so that the diameter of the non-return portion 3 in the first state is less than or equal to the diameter of the tube body 1 .

[0081] According to the above-mentioned setting method, a second receiving groove is set on the tube body 1, so that the diameter of the check portion 3 in the first state is less than or equal to the diameter of the tube body 1, which is beneficial to the movement of the output end 11 of the tube body 1 in the surrounding tissue when reaching the affected area.

[0082] In an illustrative embodiment, it further includes: a heating device 4 installed on the tube body 1 and suitable for heating the medicine flowing through the first channel 13 .

[0083] According to the above arrangement, the heating device 4 can heat the medicine flowing in the first channel 13, thereby maintaining the temperature of the medicine during the delivery process, ensuring that the medicine has a suitable hot perfusion temperature when it reaches the affected area.

[0084] Fig.10 The structural diagram of a heating device according to an embodiment of the present disclosure is schematically shown.

[0085] In an illustrative embodiment, Fig.10 As shown, at least the portion of the pipe body 1 on which the heating device 4 is mounted is configured to be coiled in a serpentine shape inside the heating device 4 .

[0086] According to the above-mentioned configuration, the serpentine-coiled portion of the tube body 1 effectively increases the heating area of ​​the portion of the tube body 1 , thereby improving the heating efficiency of the heating device 4 on the medicine inside the tube body 1 .

[0087] Fig.11 The structural diagram of a heating device according to another embodiment of the present disclosure is schematically shown.

[0088] In an illustrative embodiment, Fig.11 As shown, at least the portion of the pipe body 1 where the heating device 4 is installed is constructed in a spiral shape and is coiled around a metal guide tube 43 arranged inside the heating device 4 .

[0089] According to the above-mentioned configuration, the spiral-shaped portion of the tube body 1 effectively increases the heating area of ​​the portion of the tube body 1 , thereby improving the heating efficiency of the heating device 4 on the medicine inside the tube body 1 .

[0090] In an illustrative embodiment, it further comprises: a temperature sensing device 5 adapted to monitor the temperature of the heating device 4 and / or the heated medicine.

[0091] According to the above-mentioned setting, the temperature sensor device 5 is used to monitor the temperature of the heating device 4 and the temperature of the heated medicine in real time, ensuring that the temperature of the medicine remains within a predetermined temperature range during the entire thermal perfusion process, thereby improving the accuracy and safety of thermal perfusion.

[0092] In an illustrative embodiment, the heating device 4 and the temperature sensor 5 are installed on the pipe body 1 outside the heat insulation part 2 .

[0093] According to the above-mentioned configuration, such a layout can effectively heat and monitor the drug, while utilizing the heat-insulating portion to protect the drug from being affected by the external ambient temperature during the delivery process, thereby reducing the potential risk of thermal damage to surrounding tissues.

[0094] Fig.12 A cross-sectional schematic diagram of a thermal perfusion catheter internal heating device 4 according to yet another embodiment of the present disclosure is schematically shown.

[0095] In an illustrative embodiment, Fig.12 As shown, the heating device 4 and the temperature sensor 5 are installed between the heat insulation part 2 and the pipe body 1.

[0096] According to the above arrangement, this structural design shortens the delivery distance of the heated medicine, so that the medicine is heated in real time before reaching the affected area, the heat insulation part 2 can effectively reduce the conduction of heat to the surrounding environment, and the temperature sensor 5 can accurately monitor the temperature of the medicine. The accuracy and efficiency of the temperature of the medicine infused into the affected area are improved, while the risk of thermal damage to the tissue caused by improper temperature control is reduced.

[0097] In an illustrative embodiment, Fig.12 As shown, the temperature sensing device 5 is constructed in a cylindrical shape and is sleeved on the circumference of the pipe body 1 ; the heating device 4 covers the outside of the temperature sensing device 5 .

[0098] According to the above-mentioned setting method, the temperature sensing device 5 is designed to be cylindrical, surrounding and sleeved on the circumference of the tube body 1, and the heating device 4 covers the outside of the temperature sensing device 5, so that the temperature sensing device 5 can comprehensively monitor the temperature of the medicine flowing through the tube body 1, and the external heating device 4 can heat the flowing medicine evenly in the circumference, thereby improving the heating efficiency of the medicine and the accuracy of temperature control, and also enhancing the heat conduction and insulation effect through the cylindrical temperature sensing device 5.

[0099] In an illustrative embodiment, the temperature sensing device 5 includes a thermistor.

[0100] Fig.13 A front view of a heating device 4 according to an embodiment of the present disclosure is schematically shown; Fig.14 A front view of a heating device 4 according to yet another embodiment of the present disclosure is schematically shown.

[0101] In an illustrative embodiment, Fig.13 and Fig.14 As shown, the heating device 4 and the temperature sensor 5 are arranged in the circumference of the output end 11 of the pipe body 1 .

[0102] According to the above-mentioned setting mode, the heating and temperature monitoring directly act on the medicine that is about to leave the tube body 1 and enter the affected part, so that the temperature of the medicine can be more accurately controlled to ensure that the medicine has the best temperature when it reaches the affected part. In addition, the heating device 4 and the temperature sensing device 5 located at the output end 11 can adjust and monitor the temperature of the medicine in real time, avoiding the temperature change of the medicine during the delivery process.

[0103] In an illustrative embodiment, Fig.13 and Fig.14 As shown, the heating device 4 includes a heating coil 41 and a heating coil lead 42. The heating coil 41 is installed outside the temperature sensor device 5, and the heating coil lead 42 is suitable for connecting to an external power source.

[0104] According to the above arrangement, the heating device 4 can directly heat the medicine monitored by the temperature sensor 5, and the temperature of the medicine during the delivery process is ensured to be maintained within an ideal range through the evenly distributed heat of the heating coil 41. At the same time, the heating power and temperature can be conveniently controlled by connecting the heating coil lead 42 to an external power source, thereby improving the flexibility and safety of the use of the hot perfusion catheter.

[0105] In an illustrative embodiment, Fig.13 As shown, the heating coil 41 is configured to be spirally wound around the outside of the annular temperature sensing device 5 along the extending direction of the pipe body 1 .

[0106] In an illustrative embodiment, Fig.14 As shown, the heating coil 41 is configured to be wound in a meander shape around the circumference of the annular temperature sensor device 5 .

[0107] Fig.15 Schematically showing a front view of a thermal perfusion catheter in a first state according to yet another embodiment of the present disclosure; Fig.16 A front view of a thermal perfusion catheter in a second state according to yet another embodiment of the present disclosure is schematically shown.

[0108] In an illustrative embodiment, Fig.15 and Fig.16 As shown, the heat insulating portion 2 is configured to cover the outside of the tube body 1 within the heating range of the heating coil 41, and is suitable for isolating the heat of the heating coil 41 from being transferred to the surrounding tissues.

[0109] According to the above-mentioned configuration, the heat insulating part 2 can effectively prevent the heat generated by the heating coil 41 from being transferred to the surrounding tissues, while also preventing the heat dissipation of the drug or damage to the surrounding tissues.

[0110] In an illustrative embodiment, when the non-return portion 3 is not provided on the tube body 1, the portion of the isolating portion located at the output end is configured to abut against surrounding tissues in the second state, thereby preventing the backflow of the drug.

[0111] Fig.17 A schematic diagram of a thermal perfusion system according to an embodiment of the present disclosure is schematically shown.

[0112] According to an embodiment of the present disclosure, a thermal perfusion system is also provided, such as Fig.17 As shown, it includes the above-mentioned hot perfusion catheter; a control device 6, which is communicated with the heating device 4 and the temperature sensing device 5, and is configured to adjust the heating temperature of the heating device 4 according to the drug temperature feedback from the temperature sensing device 5; and a drug delivery device 7, which is communicated with the control device 6 and is suitable for perfusing drugs into the hot perfusion catheter.

[0113] In an illustrative embodiment, Fig.17 As shown, the control device also includes: a controller 61, a control screen 62 and a quick adjustment knob 63.

[0114] In detail, the control screen 62 is suitable for displaying and operating the controller 62 to adjust the temperature of the medicine in the hot perfusion catheter, and the quick adjustment knob 63 is suitable for the user to timely operate the controller 61 according to the temperature change to adjust the heating temperature of the medicine.

[0115] In an illustrative embodiment, Fig.17As shown, the drug delivery device 7 includes: an actuator motor 71, which is suitable for injecting drugs into the tube body 1 of the thermal perfusion catheter; and a monitoring component 72, which is suitable for monitoring the volume and / or quality of the drugs injected into the tube body 1 by the actuator motor 71.

[0116] In an illustrative embodiment, Fig.17 As shown, the monitoring component 72 is in communication connection with the controller 61 , and is adapted to provide feedback to the control device 6 on the situation of injecting the drug into the tube body 1 .

[0117] It will be appreciated by those skilled in the art that the features described in the various embodiments and / or claims of the present disclosure may be combined and / or combined in a variety of ways, even if such combinations and / or combinations are not explicitly described in the present disclosure. In particular, the features described in the various embodiments and / or claims of the present disclosure may be combined and / or combined in a variety of ways without departing from the spirit and teachings of the present disclosure. All of these combinations and / or combinations fall within the scope of the present disclosure.

[0118] The embodiments of the present disclosure are described above. However, these embodiments are only for illustrative purposes and are not intended to limit the scope of the present disclosure. Although the embodiments are described above separately, this does not mean that the measures in the various embodiments cannot be used in combination to advantage. The scope of the present disclosure is defined by the attached claims and their equivalents. Without departing from the scope of the present disclosure, those skilled in the art may make a variety of substitutions and modifications, which should all fall within the scope of the present disclosure.

Claims

1. A thermal perfusion catheter, comprising: A tube body (1) having an injection end (12) suitable for injecting a liquid drug, and an output end (11) suitable for guiding the drug to an affected area, wherein a first channel (13) is formed between the injection end (12) and the output end (11); and The heat insulating portion (2) is sleeved on the outside of the tube body (1), covers at least a portion of the tube body (1) in the axial direction, and has a first compressed state and a second expanded state; The heat insulating portion (2) in the second state is suitable for isolating at least a portion of the heat of the medicine from being dissipated to a portion other than the affected area.

2. The thermal perfusion catheter according to claim 1, wherein: The heat insulating portion (2) comprises a first air injection port (21) suitable for inflating and deflating air into the heat insulating portion (2), so that the heat insulating portion (2) switches between the first state and the second state.

3. The thermal perfusion catheter according to claim 2, wherein: The heat insulating portion (2) is configured in a spiral shape and surrounds the outside of the tube body (1) along the extension direction of the first channel (13).

4. The thermal perfusion catheter according to claim 1, further comprising a check portion (3), which is sleeved on the outside of the output end (11) and has a third state of compression and a fourth state of expansion; The check portion (3) comprises a second air injection port (31) suitable for inflating and deflating the check portion (3) so that the check portion (3) switches between the third state and the fourth state; in, The non-return portion (3) in the fourth state is suitable for preventing the backflow of the medicine from the affected area.

5. The thermal perfusion catheter according to any one of claims 1 to 4, further comprising: A heating device (4) is mounted on the tube body (1) and is suitable for heating the medicine flowing through the first channel (13).

6. The thermal perfusion catheter according to claim 5, further comprising: The temperature sensing device (5) is adapted to monitor the temperature of the heating device (4) and / or the heated medicine.

7. The thermal perfusion catheter according to claim 6, wherein: The heating device (4) and the temperature sensing device (5) are installed on the tube body (1) outside the heat insulation part (2).

8. The thermal perfusion catheter according to claim 6, wherein: The heating device (4) and the temperature sensing device (5) are installed between the heat insulating portion (2) and the pipe body (1).

9. The thermal perfusion catheter according to claim 8, wherein: The temperature sensing device (5) is constructed in a cylindrical shape and is sleeved on the circumference of the tube body (1); The heating device (4) covers the outside of the temperature sensing device (5).

10. A thermal perfusion system comprising: The thermal perfusion catheter according to any one of claims 5 to 9; a control device (6) which is in communication with the heating device (4) and the temperature sensing device (5), and is configured to adjust the heating temperature of the heating device (4) according to the temperature of the medicine fed back by the temperature sensing device (5); and The drug delivery device (7) is connected to the control device (6) in communication, and is suitable for perfusing the drug into the interior of the thermal perfusion catheter.

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