Modular chemical synthesis experimental system

Abstract

The present invention provides a modular chemical synthesis experimental system, which relates to the field of chemical engineering technology. An electrical module is installed in an electrical chamber formed inside an integrated base, and the electrical module is detachably connected to the integrated base. The type of electrical module can be increased, decreased, or replaced according to experimental requirements. The experimental module is detachably installed on the integrated base. The type of experimental module can be increased, decreased, or replaced according to experimental requirements. The system is suitable for different chemical reactions and processes, and the system can be easily expanded to add more modules or work in parallel. System maintenance and troubleshooting are also simpler and faster, alleviating the technical problems in the prior art that the chemical synthesis system design and operation are relatively complex and difficult to adapt to special or unconventional chemical reactions and processes.

Description

Technical Field

[0001] The present invention relates to the technical field of chemical engineering, in particular to a modular chemical synthesis experimental system. Background Art

[0002] Chemical synthesis automation systems utilize automated control technologies and robotics to automate reaction processes, collect data, and analyze data during chemical synthesis experiments. These systems improve the efficiency, accuracy, and safety of chemical synthesis, revolutionizing fields such as chemical research and drug development.

[0003] Some of the shortcomings of the current chemical synthesis system mainly include:

[0004] (1) Complexity: The design and operation of chemical automated synthesis systems are often complex and require technical knowledge in interdisciplinary fields such as chemistry, chemical engineering, mechanics, fluids, electronics, and software.

[0005] (2) Flexibility limitations: Currently, most chemical synthesis experimental systems are customized. It is difficult to migrate and reconstruct them for synthetic experiments of new molecules, and it is difficult to adapt to special or unconventional chemical reactions and processes.

[0006] (3) Scale adaptability: Automated systems are often more suitable for large-scale production. For small-scale or laboratory-scale synthesis, these systems may not be as efficient as manual operations, and the systems may still be difficult to adapt to special or unconventional chemical reactions and processes. Summary of the Invention

[0007] The purpose of the present invention is to provide a modular chemical synthesis experimental system to alleviate the technical problems existing in the prior art that the design and operation of chemical synthesis systems are relatively complex and difficult to adapt to special or unconventional chemical reactions and processes.

[0008] The modular chemical synthesis experimental system provided by the present invention comprises: an integrated base, an electrical module, an experimental module and a mobile module;

[0009] An electrical chamber is formed inside the integrated base, the electrical module is disposed in the electrical chamber, and the electrical module is detachably connected to the inner wall of the integrated base;

[0010] The experimental module is arranged on the outer surface of the integrated base, and the experimental module is detachably connected to the integrated base;

[0011] The movable module is arranged above the experimental module, and is configured to be movable relative to the experimental module so that the experimental module can complete a sampling operation or a sample adding operation.

[0012] In an alternative embodiment,

[0013] The experimental module includes a reaction module;

[0014] The reaction module includes a reaction box and a reaction kettle;

[0015] The reaction box is detachably connected to the integrated base, and the reaction kettle is arranged on the reaction box. The reaction kettle is used to hold liquid samples and / or solid samples.

[0016] In an alternative embodiment,

[0017] The reaction module further includes a reaction stirring component and a reaction heating component;

[0018] The reaction stirring member is connected to the reaction box, and the stirring driving end of the reaction stirring member extends into the reactor;

[0019] The reaction heating component is disposed in the reaction box, and the reaction heating component is configured to heat the reactor.

[0020] In an alternative embodiment,

[0021] The experimental module also includes a solid sample addition module;

[0022] The solid sample loading module contains a solid sample, and the moving module is used to drive the solid sample in the solid sample loading module to move.

[0023] In an alternative embodiment,

[0024] The solid sample loading module includes a solid sample loading base, a sample loading rack, a powder sample loading head and a solid sample loading drive component;

[0025] The solid sample loading base is detachably connected to the integrated base, the sample loading rack is arranged on the solid sample loading base, and the solid sample loading drive component and the plurality of powder sample loading heads are placed on the sample loading rack;

[0026] The solid sample loading drive component is configured to be capable of being drivingly connected to the powder loading head so as to cause the powder in the powder loading head to fall;

[0027] The moving module is configured to drive the solid sample loading driving component to move, so that the solid sample loading driving component is connected to the powder sample loading head through transmission.

[0028] In an alternative embodiment,

[0029] The moving module is configured to drive the solid loading driving member and the powder loading head to move above the reactor, so that the powder in the powder loading head falls into the reactor to complete the powder loading operation.

[0030] In an alternative embodiment,

[0031] The powder loading head comprises a powder loading housing, an anti-blocking threaded rod, a transmission assembly and a conveying screw rod;

[0032] The powder loading shell is formed with a powder inner cavity for placing powder, and the powder loading shell is formed with a powder conveying cavity connected to the bottom of the powder inner cavity, and the powder loading shell is provided with a powder outlet, and the powder outlet is connected to the powder conveying cavity;

[0033] The anti-blocking threaded rod is disposed in the powder loading housing, one end of the anti-blocking threaded rod extends into the powder inner cavity, and the other end of the anti-blocking threaded rod is connected to the transmission assembly. The anti-blocking threaded rod is configured to rotate along its own axis to drive the powder in the powder inner cavity to fall into the powder conveying cavity;

[0034] One end of the conveying screw extends into the powder conveying chamber, and the other end of the conveying screw extends from the powder loading housing and is capable of being transmission-connected to the solid loading drive component. The conveying screw is connected to the transmission assembly, and the solid loading drive component is used to drive the conveying screw to rotate along its own axis to drive the powder in the powder conveying chamber to fall out of the powder outlet.

[0035] The transmission assembly is used to make the conveying screw rod and the anti-blocking threaded rod rotate synchronously.

[0036] In an alternative embodiment,

[0037] The solid sample loading module further includes a weighing platform;

[0038] The weighing platform is detachably connected to the integrated base, the top surface of the weighing platform is slidably connected to a movable plate, the movable plate is provided with a placement platform, the placement platform is provided with a drop opening, the powder outlet of the powder dosing head placed on the placement platform can be connected to the drop opening, so that the powder in the powder dosing head can fall into the balance container inside the weighing platform;

[0039] The moving module is configured to drive the solid sample loading driving component and the powder sample loading head to move to the placement table together, so that the powder outlet is communicated with the drop port.

[0040] In an alternative embodiment,

[0041] The experimental module also includes a liquid sampling module;

[0042] The liquid sample adding module contains the liquid sample, and the moving module is used to drive the liquid sample in the liquid sample adding module to move into the reaction kettle.

[0043] In an alternative embodiment,

[0044] The liquid sample adding module includes a liquid pump assembly;

[0045] The pump liquid assembly includes a liquid sample addition base, a plunger pump, a buffer bottle and a switching valve;

[0046] The liquid sample loading base comprises an upper support and a lower support connected to each other, the lower support is detachably connected to the integrated base, and a plurality of reagent bottles are placed on the lower support;

[0047] The plunger pump and the switching valve are both installed on the upper support;

[0048] The reaction kettle and the plurality of reagent bottles are arranged in parallel and are connected to the switching valve;

[0049] The plunger pump is connected to the switching valve pipeline, and the buffer bottle is arranged on the pipeline between the plunger pump and the switching valve. The switching valve is used to control the connection and disconnection between the reactor and the buffer bottle, and to control the connection and disconnection between the multiple reagent bottles and the buffer bottle;

[0050] The plunger pump is configured to be able to suck the liquids in the plurality of reagent bottles into the buffer bottle, and to be able to pump the liquids in the buffer bottle into the reactor.

[0051] In an alternative embodiment,

[0052] The liquid loading module further includes a pipetting component;

[0053] The pipetting assembly includes a pipetting base, a pipette recovery box, a pipette hanger and a pipette box;

[0054] The pipetting base is detachably connected to the integrated base, and the pipetting gun recovery box, the pipetting gun rack and the pipetting gun box are all arranged on the pipetting base;

[0055] The pipette gun box stores a pipette gun component, and the moving module is configured to grab the pipette gun component in the pipette gun box and drive the pipette gun component to move, so that the pipette gun component absorbs the liquid sample in the reagent bottle and drips it into the reactor;

[0056] The pipette gun rack is used to hang the pipette gun component;

[0057] The pipette recovery box is used to recover the pipette components after use.

[0058] In an alternative embodiment,

[0059] The electrical module includes at least one of a power module, a communication module, a vacuum module, a water separation module and a gas separation module.

[0060] The modular chemical synthesis experimental system provided by the present invention has an electrical module installed in an electrical chamber formed inside an integrated base, and the electrical module is detachably connected to the integrated base. The type of electrical module can be increased, decreased or replaced according to experimental requirements. The experimental module can be detachably installed on the integrated base. The type of experimental module can be increased, decreased or replaced according to experimental requirements. It is suitable for different chemical reactions and processes, and the system can be easily expanded to add more modules or work in parallel. The maintenance and troubleshooting of the system are also simpler and faster, alleviating the technical problems in the prior art that the design and operation of chemical synthesis systems are relatively complex and difficult to adapt to special or unconventional chemical reactions and processes. BRIEF DESCRIPTION OF THE DRAWINGS

[0061] In order to more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the specific embodiments or the description of the prior art. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0062] Figure 1 A schematic diagram of the overall structure of a modular chemical synthesis experimental system provided by an embodiment of the present invention;

[0063] Figure 2 A schematic diagram of the structure of a modular chemical synthesis experimental system from a top-down perspective provided by an embodiment of the present invention;

[0064] Figure 3 A schematic diagram of the area division of a modular chemical synthesis experimental system provided by an embodiment of the present invention;

[0065] Figure 4 A schematic diagram of the layout of a modular chemical synthesis experimental system provided in an embodiment of the present invention;

[0066] Figure 5 A schematic diagram of the structure of a reaction module in a modular chemical synthesis experimental system provided by an embodiment of the present invention;

[0067] Figure 6 A schematic structural diagram of a solid sample loading module in a modular chemical synthesis experimental system provided by an embodiment of the present invention;

[0068] Figure 7 A schematic structural diagram of a powder loading head in a modular chemical synthesis experimental system provided by an embodiment of the present invention;

[0069] Figure 8 A schematic structural diagram of a pump assembly in a modular chemical synthesis experimental system provided by an embodiment of the present invention;

[0070] Figure 9 A schematic diagram of the structure of a pipetting component in a modular chemical synthesis experimental system provided by an embodiment of the present invention;

[0071] Figure 10 A schematic structural diagram of an electrical module and an integrated base in a modular chemical synthesis experimental system provided by an embodiment of the present invention.

[0072] Icons: 100-integrated base; 200-electrical module; 210-power module; 220-communication module; 230-water distribution module; 240-gas distribution module; 300-experimental module; 310-reaction module; 311-reaction box; 312-reactor; 313-reaction stirring component; 314-reaction heating component; 320-solid loading module; 321-solid loading base; 322-loading rack; 323-powder loading head; 3231-powder loading housing; 3232-anti-blocking threaded rod; 3233-transmission assembly; 3234 - conveying screw rod; 324 - solid sample loading drive component; 325 - weighing platform; 326 - moving plate; 327 - placing platform; 328 - dropping port; 330 - liquid sample loading module; 331 - liquid sample loading base; 332 - plunger pump; 333 - switching valve; 334 - pipetting base; 335 - pipette recovery box; 336 - pipette hanger; 337 - pipette box; 338 - buffer bottle holder; 339 - reagent bottle; 400 - moving module; 410 - X-axis slide rail; 420 - Y-axis slide rail; 430 - Z-axis slide rail; 440 - gripper component. DETAILED DESCRIPTION

[0073] The technical solution of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the embodiments described are only some embodiments of the present invention, not all embodiments. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts shall fall within the scope of protection of the present invention.

[0074] In the description of the present invention, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings and are intended solely to facilitate and simplify the description of the present invention. They are not intended to indicate or imply that the devices or components referred to must have, be constructed, or operate in a specific orientation, and therefore should not be construed as limitations on the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0075] In the description of the present invention, it should be noted that, unless otherwise expressly specified or limited, the terms "mounted," "connected," and "connected" should be understood in a broad sense. For example, they may refer to fixed, detachable, or integral connections; mechanical or electrical connections; direct or indirect connections through an intermediate medium; and internal communication between two components. Those skilled in the art will understand the specific meanings of the above terms in the present invention based on specific circumstances.

[0076] The following describes the specific embodiments of the present invention in detail with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are only used to illustrate and explain the present invention and are not intended to limit the present invention.

[0077] like Figure 1 、 Figure 2 As shown, the modular chemical synthesis experimental system provided in this embodiment includes: an integrated base 100, an electrical module 200, an experimental module 300 and a mobile module 400; Figure 3 As shown, the whole experimental system is divided into three areas: upper, middle and lower. The bottom part is the integrated base 100 area. The integrated base 100 is a box-type structure. The interior of the integrated base 100 forms an electrical chamber, as shown in FIG. Figure 10As shown, the electrical module 200 is disposed in the electrical chamber. The sidewalls of the integrated base 100 have openings that serve as interfaces for gas, communication, and circuitry. The electrical module 200 specifically includes at least one of a water distribution module 230, a gas distribution module 240, a vacuum module, a communication module 220, and a power supply module 210, providing the experimental modules 300 on the integrated base 100 with the corresponding water, gas, electricity, and communication infrastructure. The specific type of electrical module 200 is selected based on experimental needs. Since the electrical module is detachably connected to the inner wall of the integrated base 100, the specific type of electrical module 200 can be freely replaced, facilitating subsequent maintenance of the electrical module 200. The middle portion is the synthetic experiment area, where the solid sample loading module 320, the liquid sample loading module 330, and the reaction module 310 can be placed. The top portion is the mobile area for the robotic module, which can be used for robotic arm motion or multi-axis module motion. Of particular note, interference between the robotic module and the synthetic experiment area should be carefully considered during module assembly.

[0078] The middle area of ​​the overall experimental system is the synthetic experimental area, and the experimental module 300 is located in the synthetic experimental area. The experimental module 300 is arranged on the outer surface of the integrated base 100, and the experimental module 300 is detachably connected to the integrated base 100, which facilitates the disassembly and assembly of the experimental module 300. The specific type of the experimental module 300 is selected according to the experimental needs.

[0079] It should be noted that the electrical module 200 in the integrated base 100 and the experimental module 300 on the integrated base 100 need to be arranged in a plane plan, for example Figure 4 As shown, each module in the experimental module 300 has three sizes. Module size type 1 is a square with a side length of 200 mm, module size type 2 is a rectangle with a length of 400 mm and a width of 200 mm, and module size 3 is a positive direction with a side length of 400 mm. The three sizes are combined and pieced together into a rectangle according to the number of uses, making the overall system more compact.

[0080] The upper area of ​​the overall experimental system is the mobile area, and the mobile module 400 is located in the mobile area. The mobile module 400 is set above the experimental module 300. The mobile module 400 is configured to be able to move relative to the experimental module 300 so that the experimental module 300 can complete the sampling operation or the sample addition operation.

[0081] Specifically, the mobile module 400 can be set as a robot or a three-axis gripper assembly. Preferably, the mobile module 400 is set as a three-axis gripper assembly, which includes an X-axis slide rail 410, a Y-axis slide rail 420, a Z-axis slide rail 430 and a gripper member 440. The X-axis slide rail 410 is arranged along a first direction, the Y-axis slide rail 420 is arranged along a second direction, and the Z-axis slide rail 430 is arranged along a third direction. The first direction, the second direction and the third direction are arranged perpendicular to each other to form a three-axis movement. The X-axis slide rail 410 is supported by a support frame. Supported above the experimental module 300, the Y-axis slide rail 420 is slidably connected to the X-axis slide rail 410 so that the Y-axis slide rail 420 can move along the X-axis slide rail 410, the Z-axis slide rail 430 is slidably connected to the Y-axis slide rail 420 so that the Z-axis slide rail 430 can move along the Y-axis slide rail 420, and the gripping member 440 is slidably connected to the Z-axis slide rail 430 so that the gripping member 440 can move along the Z-axis slide rail 430, thereby realizing three-axis movement of the gripping member 440 and realizing automated sampling or adding operations.

[0082] In an optional embodiment, if Figure 5 As shown, the experimental module 300 includes a reaction module 310; the reaction module 310 includes a reaction box 311 and a reactor 312. The reaction box 311 is specifically a box-type structure. The bottom wall of the reaction box 311 is detachably connected to the integrated base 100. Specifically, the detachable connection between the reaction box 311 and the integrated base 100 can be achieved by bolts. The reaction base is provided with a placement groove, the notch of the placement groove faces upward, the reactor 312 is placed in the placement groove, and the top opening of the reactor 312 protrudes from the top of the reaction base. The reactor 312 is used to hold liquid samples and / or solid samples to achieve chemical reactions in the reactor 312.

[0083] In an optional embodiment, the reaction module 310 also includes a reaction stirring component 313 and a reaction heating component 314; the reaction stirring component 313 is connected to the reaction box body 311. Specifically, a support column is provided on the top surface of the reaction box body 311, and a support plate is fixed on the support column. The reaction stirring component 313 includes a driving motor and a stirring member. The driving motor is installed on the support plate, and the driving shaft of the driving motor is connected to the stirring member. The stirring member extends into the reactor 312. The driving force generated by the driving motor drives the stirring member to rotate, so that the stirring member stirs the liquid in the reactor 312.

[0084] Optionally, the reaction module 310 is further provided with a reaction heating component 314, which is arranged in the reaction box 311. The reaction heating component 314 is configured to heat the reactor 312. The reaction heating component 314 is an existing product, and the specific type and structure of the reaction heating component 314 are selected according to actual conditions.

[0085] In addition, the reaction module 310 may also be provided with a reaction cooling component, which is provided in the reaction box 311 and is used to cool the reactor 312. The reaction cooling component is an existing product, and the specific type and structure of the reaction cooling component are selected according to actual conditions.

[0086] In an optional embodiment, if Figure 6 As shown, the experimental module 300 further includes a solid sample loading module 320 ; the solid sample loading module 320 contains solid samples, and the moving module 400 is used to drive the solid sample in the solid sample loading module 320 to move, thereby completing the solid sample loading operation.

[0087] Regarding the structure and shape of the solid sample loading module 320, specifically:

[0088] The solid loading module 320 includes a solid loading base 321 , a loading rack 322 , a powder loading head 323 and a solid loading driving member 324 .

[0089] The solid loading base 321 is detachably connected to the integrated base 100. The solid loading base 321 is a plate-like structure. The solid loading base 321 can be detachably connected to the integrated base 100 by bolts. The loading rack 322 is arranged on the solid loading base 321. The solid loading drive component 324 and multiple powder loading heads 323 are all placed on the loading rack 322.

[0090] The solid loading drive component 324 is configured to be able to be transmission-connected with the powder loading head 323 so that the powder in the powder loading head 323 falls. It should be noted that there can be only one solid loading drive component 324, while the powder loading head 323 can be provided with multiple. The solid loading drive component 324 is driven to move by the moving module 400, so that the solid loading drive component 324 can be selectively transmission-connected with the powder loading head 323.

[0091] Regarding the structure and shape of the powder adding head 323, specifically:

[0092] like Figure 7 As shown, the powder loading head 323 includes a powder loading housing 3231 , an anti-blocking threaded rod 3232 , a transmission assembly 3233 and a conveying screw rod 3234 ;

[0093] The powder loading shell 3231 is a box-type structure, and a powder cavity for placing powder is formed in the powder loading shell 3231. The powder cavity is a funnel-shaped structure, and the opening size at the top of the powder cavity is larger than the opening size at the bottom of the powder cavity. A powder conveying cavity connected to the bottom of the powder cavity is formed in the powder loading shell 3231. The powder loading shell 3231 is provided with a powder outlet, and the powder outlet is connected to the powder conveying cavity. The powder sample in the powder cavity falls freely into the powder conveying cavity, and the powder sample in the powder conveying cavity is discharged through the powder outlet.

[0094] In order to prevent the powder sample in the powder cavity from being blocked, an anti-blocking threaded rod 3232 is provided. The anti-blocking threaded rod 3232 is arranged in the powder loading shell 3231. One end of the anti-blocking threaded rod 3232 extends into the powder cavity, and the other end of the anti-blocking threaded rod 3232 is connected to the transmission assembly 3233. The anti-blocking threaded rod 3232 is configured to be able to rotate along its own axis, so that the threaded ribs on the surface of the anti-blocking threaded rod 3232 rotate, driving the powder in the powder cavity to fall into the powder conveying cavity, ensuring that the powder sample in the powder cavity can smoothly enter the powder conveying cavity.

[0095] One end of the conveying screw rod 3234 extends into the powder conveying chamber, and the other end of the conveying screw rod 3234 extends from the powder loading housing 3231 and can be connected to the solid loading drive component 324 for transmission, and the conveying screw rod 3234 is connected to the transmission assembly 3233. The solid loading drive component 324 is used to drive the conveying screw rod 3234 to rotate along its own axis to drive the powder in the powder conveying chamber to fall out from the powder outlet.

[0096] Specifically, a spline is provided at one end of the conveying screw rod 3234 extending out of the powder loading housing 3231, and a spline groove is provided on the driving shaft of the solid loading drive component 324. The torque and torque are transmitted through the cooperation of the spline and the spline groove, thereby realizing the transmission connection between the conveying screw rod 3234 and the solid loading drive component 324.

[0097] The transmission assembly 3233 is used to make the conveying screw rod 3234 and the anti-blocking threaded rod 3232 rotate synchronously. Specifically, the transmission assembly 3233 includes a first transmission gear and a second transmission gear. The first transmission gear is sleeved on the anti-blocking threaded rod 3232, and the first transmission gear is fixedly connected to the anti-blocking threaded rod 3232. The second transmission gear is sleeved on the conveying screw rod 3234, and the second transmission gear is fixedly connected to the conveying screw rod 3234. The first transmission gear and the second transmission gear are meshed and connected, so that when the conveying screw rod 3234 is driven to rotate by the solid sample loading drive component 324, the anti-blocking threaded rod 3232 is driven to rotate synchronously by the first transmission gear and the second transmission gear, so that only one driving component is used to simultaneously drive the anti-blocking threaded rod 3232 and the conveying screw rod 3234 to rotate together.

[0098] In an optional embodiment, the solid loading module 320 also includes a weighing platform 325; the weighing platform 325 is a box-type structure, the bottom of the weighing platform 325 is detachably connected to the integrated base 100, and the top surface of the weighing platform 325 is slidably connected to a movable plate 326, and the movable plate 326 can slide relative to the weighing platform 325, and a placement platform 327 is provided on the movable plate 326, and the placement platform 327 is provided with a drop port 328. The movable module 400 can drive the solid loading drive component 324 and the powder loading head 323 to move together to the placement platform 327, so that the powder outlet is connected to the drop port 328, so that the powder in the powder loading head 323 can fall into the balance container inside the weighing platform 325. When it is necessary to take out the powder sample on the balance container, the movable plate 326 is driven to move so that the top of the weighing platform 325 has an opening, so that the pipette gun component can be extended into the weighing platform 325 to take out the powder sample on the balance container.

[0099] After the solid sample loading drive component 324 is connected to the powder loading head 323 by transmission, powder loading can be achieved in two ways. Method 1: The mobile module 400 drives the solid sample loading drive component 324 and the powder loading head 323 to move together above the reactor 312, and the solid sample loading drive component 324 is started to make the powder in the powder loading head 323 fall into the reactor 312 to complete the powder loading operation. After the loading is completed, the mobile module 400 puts the powder loading head 323 and the solid sample loading drive component 324 back to their original positions; Method 2: The mobile module 400 drives the solid sample loading drive component 324 and the powder loading head 323 moves together to the weighing platform 325, and the solid sampling drive component 324 is started to allow the powder in the powder sampling head 323 to fall into the balance container inside the weighing platform 325. After moving, the mobile module 400 grabs the pipette gun component, allowing the pipette gun component to absorb the liquid, and then add it to the balance container to prepare the suspension. The mobile module 400 drives the pipette gun component with the suspension to move above the reactor 312 for sampling. After the sampling is completed, the mobile module 400 puts the powder sampling head 323 and the solid sampling drive component 324 back to their original positions, and places the pipette gun component in the pipette gun recovery box 335.

[0100] In an optional embodiment, the experimental module 300 further includes a liquid loading module 330 ; the liquid loading module 330 contains a liquid sample, and the moving module 400 is used to move the liquid sample in the liquid loading module 330 into the reaction vessel 312 .

[0101] Regarding the structure and shape of the liquid sample adding module 330, specifically:

[0102] like Figure 8As shown, the liquid loading module 330 includes a pump liquid assembly; the pump liquid assembly includes a liquid loading base 331, a plunger pump 332, a buffer bottle and a switching valve 333; the liquid loading base 331 includes an upper support and a lower support that are connected to each other, the lower support is detachably connected to the integrated base 100, a plurality of reagent bottles 339 are placed on the lower support, the upper support is provided with a buffer bottle bracket 338, and the buffer bottle is supported by the buffer flat bracket, the plunger pump 332 and the switching valve 333 are both installed on the upper support, and through the setting of the upper bracket and the lower bracket, an upper and lower double-layer structure is formed, the structure is more compact, and the plane space is saved.

[0103] The reactor 312 and multiple reagent bottles 339 are arranged in parallel and are all connected to the switching valve 333. The plunger pump 332 is connected to the switching valve 333 pipeline. The buffer bottle is arranged on the pipeline between the plunger pump 332 and the switching valve 333. The switching valve 333 is used to control the connection and disconnection between the reactor 312 and the buffer bottle, and to control the connection and disconnection between the multiple reagent bottles 339 and the buffer bottle. The plunger pump 332 is configured to be able to suck the liquid in the multiple reagent bottles 339 into the buffer bottle, and to be able to pump the liquid in the buffer bottle into the reactor 312.

[0104] For example, when it is necessary to pump the liquid in the first reagent bottle 339 into the reactor 312, the switching valve 333 is switched to a state in which the first reagent bottle 339 is connected to the cache bottle, and the plunger pump 332 is started to suck the liquid sample in the first reagent bottle 339 into the cache bottle. After the suction is completed, the switching valve 333 is switched to a state in which the cache bottle is connected to the reactor 312, and the plunger pump 332 is started to pump the liquid sample in the cache bottle into the reactor 312 to complete the liquid sampling.

[0105] Due to the setting of the buffer bottle and the switching valve 333, the liquids in different reagent bottles 339 can be mixed in the buffer bottle, and the mixed liquid is then pumped into the reactor 312. Moreover, during the process of pumping liquid, the plunger pump 332 pumps the liquid from the reagent bottle 339 into the buffer bottle instead of into the plunger pump 332, thereby effectively preventing the plunger pump 332 from being corroded by the liquid. Therefore, the buffer bottle not only plays the role of liquid mixing, but also effectively prevents the plunger pump 332 from being corroded.

[0106] In addition, it should be noted that, optionally, the reagent bottle 339 is sealed. Since the reagent bottle 339 is sealed, when the plunger pump 332 sucks the liquid in the reagent bottle 339, the gas in the reagent bottle 339 gradually decreases, resulting in the liquid in the reagent bottle 339 being unable to be sucked. Therefore, a ventilation line can be inserted into the reagent bottle 339 to introduce protective gas into the reagent bottle 339, and a solenoid valve can be set on the ventilation line to control the on and off of the ventilation line.

[0107] In an optional embodiment, if Figure 9As shown, the liquid loading module 330 also includes a pipetting assembly; the pipetting assembly includes a pipetting base 334, a pipette gun recovery box 335, a pipette gun hanger 336 and a pipette gun box 337; the pipette base 334 is a plate-like structure, and the pipette base 334 can be detachably connected to the integrated base 100 by bolts, and the pipette gun recovery box 335, the pipette gun hanger 336 and the pipette gun box 337 are all arranged on the pipetting base 334.

[0108] The pipette box 337 stores multiple pipette components. The mobile module 400 can grab the pipette components in the pipette box 337 and drive the pipette components to move, so that the pipette components absorb the liquid sample in the reagent bottle 339 and drip it into the reactor 312. The pipette hanger 336 can hang the pipette components to facilitate the use of the pipette components. After use, the pipette components are moved to the pipette recovery box 335 by the mobile module 400 to recycle the used pipette components.

[0109] When using the modular chemical synthesis experimental system provided in this embodiment, one or two modules can be used separately in the above manner, or all modules can be used. When all modules are used, solid sampling can adopt the above-mentioned powder sampling method 1 and directly add the sample to the reactor 312, or adopt the above-mentioned powder sampling method 2, after weighing, prepare a suspension on the weighing table 325, and then use the pipette component to add the suspension to the reactor 312; liquid sampling can adopt the plunger pump 332 to pump the liquid sample into the reactor 312, or use the pipette component to suck the liquid sample in the reagent bottle 339 and drop it into the reactor 312; the liquid and solid in the reactor 312 are mixed and reacted, and heating, cooling or stirring can be performed during the reaction process. It should be noted that mixing, heating, cooling or stirring can be selected according to the experimental situation; after the reaction is completed, the liquid in the reactor 312 is transferred by the plunger pump 332, or the pipette component can be used to transfer the liquid.

[0110] The modular chemical synthesis experimental system provided in this embodiment has the following advantages:

[0111] (1) From the functional realization level, it can cover solid sampling, liquid sampling, reaction heating, temperature control, stirring, atmosphere protection, etc.;

[0112] (2) In terms of flexibility, modules can be added, removed, or replaced according to experimental requirements to adapt to different chemical reactions and processes;

[0113] (3) Scalability: As research needs grow, the system can be easily expanded to add more modules or parallel workstations;

[0114] (4) Easy maintenance: Due to the modular design, system maintenance and troubleshooting are usually simpler and faster.

[0115] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the above embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A modular chemical synthesis experimental system, characterized in that: include: An integrated base (100), an electrical module (200), an experimental module (300) and a mobile module (400); An electrical chamber is formed inside the integrated base (100), the electrical module (200) is arranged in the electrical chamber, and the electrical module (200) is detachably connected to the inner wall of the integrated base (100); The experimental module (300) is arranged on the outer surface of the integrated base (100), and the experimental module (300) and the integrated base (100) are detachably connected; The mobile module (400) is arranged above the experimental module (300), and the mobile module (400) is configured to be movable relative to the experimental module (300) so as to enable the experimental module (300) to complete a sampling operation or a sample addition operation; The experimental module (300) includes a reaction module (310); The reaction module (310) includes a reaction box (311) and a reaction kettle (312); The reaction box (311) is detachably connected to the integrated base (100), and the reaction kettle (312) is arranged on the reaction box (311), and the reaction kettle (312) is used to hold liquid samples and / or solid samples; The experimental module (300) further includes a solid sample addition module (320); The solid sample loading module (320) contains a solid sample, and the moving module (400) is used to drive the solid sample in the solid sample loading module (320) to move; The solid loading module (320) comprises a solid loading base (321), a loading rack (322), a powder loading head (323), and a solid loading drive component (324); The solid sample loading base (321) is detachably connected to the integrated base (100), the sample loading rack (322) is arranged on the solid sample loading base (321), and the solid sample loading drive component (324) and the plurality of powder sample loading heads (323) are placed on the sample loading rack (322); The solid loading drive component (324) is configured to be capable of being drivingly connected to the powder loading head (323) so as to cause the powder in the powder loading head (323) to fall; The moving module (400) is configured to be able to drive the solid sample loading drive component (324) to move, so that the solid sample loading drive component (324) is connected to the powder loading head (323) in a transmission manner.

2. The modular chemical synthesis experimental system according to claim 1, characterized in that: The reaction module (310) further includes a reaction stirring component (313) and a reaction heating component (314); The reaction stirring member (313) is connected to the reaction box (311), and the stirring drive end of the reaction stirring member (313) extends into the reaction kettle (312); The reaction heating component (314) is disposed in the reaction box (311), and the reaction heating component (314) is configured to heat the reaction kettle (312).

3. The modular chemical synthesis experimental system according to claim 2, characterized in that: The moving module (400) is configured to drive the solid loading drive component (324) and the powder loading head (323) to move together to above the reactor (312), so that the powder in the powder loading head (323) falls into the reactor (312), thereby completing the powder loading operation.

4. The modular chemical synthesis experimental system according to claim 2, characterized in that: The powder loading head (323) comprises a powder loading housing (3231), an anti-blocking threaded rod (3232), a transmission assembly (3233) and a conveying screw rod (3234); A powder inner cavity for placing powder is formed in the powder loading housing (3231), and a powder conveying cavity communicating with the bottom of the powder inner cavity is formed in the powder loading housing (3231). The powder loading housing (3231) is provided with a powder outlet, and the powder outlet is communicated with the powder conveying cavity; The anti-blocking threaded rod (3232) is arranged in the powder loading housing (3231), one end of the anti-blocking threaded rod (3232) extends into the powder inner cavity, and the other end of the anti-blocking threaded rod (3232) is connected to the transmission assembly (3233), and the anti-blocking threaded rod (3232) is configured to be able to rotate along its own axis to drive the powder in the powder inner cavity to fall into the powder conveying cavity; One end of the conveying screw rod (3234) extends into the powder conveying chamber, and the other end of the conveying screw rod (3234) extends from the powder loading housing (3231) and is capable of being transmission-connected to the solid loading drive component (324), and the conveying screw rod (3234) is connected to the transmission assembly (3233). The solid loading drive component (324) is used to drive the conveying screw rod (3234) to rotate along its own axis, so as to drive the powder in the powder conveying chamber to fall out from the powder outlet; The transmission assembly (3233) is used to enable the conveying screw rod (3234) and the anti-blocking threaded rod (3232) to rotate synchronously.

5. The modular chemical synthesis experimental system according to claim 4, characterized in that: The solid sample loading module (320) further includes a weighing platform (325); The weighing platform (325) is detachably connected to the integrated base (100); the top surface of the weighing platform (325) is slidably connected to a movable plate (326); a placement platform (327) is provided on the movable plate (326); the placement platform (327) is provided with a drop opening (328); the powder outlet of the powder loading head (323) placed on the placement platform (327) can be connected to the drop opening (328), so that the powder in the powder loading head (323) can fall into the balance container inside the weighing platform (325); The moving module (400) is configured to drive the solid loading drive component (324) and the powder loading head (323) to move onto the placement table (327) so that the powder outlet is connected to the drop port (328).

6. The modular chemical synthesis experimental system according to claim 1, characterized in that: The experimental module (300) further includes a liquid sample addition module (330); The liquid sample adding module (330) contains a liquid sample, and the moving module (400) is used to drive the liquid sample in the liquid sample adding module (330) to move into the reaction kettle (312).

7. The modular chemical synthesis experimental system according to claim 6, characterized in that: The liquid sample adding module (330) includes a liquid pump assembly; The pump liquid assembly includes a liquid sample addition base (331), a plunger pump (332), a buffer bottle and a switching valve (333); The liquid sample loading base (331) comprises an upper support and a lower support connected to each other, the lower support being detachably connected to the integrated base (100), and a plurality of reagent bottles (339) being placed on the lower support; The plunger pump (332) and the switching valve (333) are both installed on the upper support; The reaction kettle (312) and the plurality of reagent bottles (339) are arranged in parallel and are all connected to the switching valve (333); The plunger pump (332) is connected to the switching valve (333) pipeline, and the buffer bottle is arranged on the pipeline between the plunger pump (332) and the switching valve (333). The switching valve (333) is used to control the connection and disconnection between the reactor (312) and the buffer bottle, and to control the connection and disconnection between the plurality of reagent bottles (339) and the buffer bottle; The plunger pump (332) is configured to be able to suck the liquid in the plurality of reagent bottles (339) into the buffer bottle, and to be able to pump the liquid in the buffer bottle into the reaction kettle (312).

8. The modular chemical synthesis experimental system according to claim 7, characterized in that: The liquid sample addition module (330) further includes a pipetting component; The pipetting assembly includes a pipetting base (334), a pipetting gun recovery box (335), a pipetting gun rack (336) and a pipetting gun box (337); The pipetting base (334) is detachably connected to the integrated base (100), and the pipetting gun recovery box (335), the pipetting gun hanger (336) and the pipetting gun box (337) are all arranged on the pipetting base (334); The pipette gun box (337) stores a pipette gun component, and the moving module (400) is configured to be able to grab the pipette gun component in the pipette gun box (337) and drive the pipette gun component to move, so that the pipette gun component absorbs the liquid sample in the reagent bottle (339) and drips it into the reaction kettle (312); The pipette hanger (336) is used to hang the pipette component; The pipette recovery box (335) is used to recover the pipette components after use.

9. The modular chemical synthesis experimental system according to claim 1, characterized in that: The electrical module (200) comprises at least one of a power module (210), a communication module (220), a vacuum module, a water separation module (230), and a gas separation module (240).

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