A method and kit for cleaning the surface of ex vivo tissue after magnetic resonance imaging.

By using a combination of hexane, pentane, alcohols, and phosphate buffer, the problem of incomplete cleaning of fluorinated oil on the surface of ex vivo biological tissues after magnetic resonance imaging was solved, achieving rapid and thorough cleaning, simplifying the process, and ensuring the integrity of the biological tissues.

CN119216282BActive Publication Date: 2026-05-26HAINAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HAINAN UNIV
Filing Date
2024-09-29
Publication Date
2026-05-26

AI Technical Summary

Technical Problem

In existing technologies, the cleaning of fluorinated oil on the surface of ex vivo biological tissues after magnetic resonance imaging is incomplete, slow, and complex, affecting subsequent research and processing.

Method used

Fluorinated oil was gradually removed by rinsing with a constant-temperature shaker using a combination of hexane, pentane, alcohol, and phosphate buffer from the kit.

Benefits of technology

It enables rapid and thorough removal of fluorinated oil, simplifies the process, ensures the integrity of biological tissues, and is suitable for different types of biological tissues.

✦ Generated by Eureka AI based on patent content.

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Abstract

This invention discloses a kit for cleaning the surface of ex vivo tissue after magnetic resonance imaging (MRI), comprising reagent A, reagent B, reagent C, and reagent D, wherein: reagent A is a mixture of n-hexane and n-pentane; reagent B is a mixture of n-hexane, n-pentane, and an alcohol; reagent C is an alcohol; and reagent D is a mixture of an alcohol and phosphate buffer. This invention also discloses a method for cleaning the surface of ex vivo tissue after MRI, comprising the step of sequentially rinsing the ex vivo biological tissue sample after MRI using reagents A, B, C, and D from the kit of this invention. This invention introduces n-hexane into the kit to remove perfluoropolyether from the tissue surface, simultaneously solving the technical problems of incomplete cleaning of fluorinated oil from tissue surfaces and slow, complex cleaning processes in existing technologies.
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