A bionic polyetheretherketone dental implant material and its preparation method

Abstract

The present invention relates to the technical field of biomedical materials, and particularly relates to a biomimetic polyetheretherketone dental implant material and a preparation method thereof. The preparation method of the biomimetic polyetheretherketone dental implant comprises the following steps: mixing polyetheretherketone with a modified material and glass fiber in ethanol, and drying to obtain composite powders with gradient changes in the modified material and glass fiber respectively; pressing composite powders containing different contents of glass fiber / modified material / polyetheretherketone into composite powder disks respectively, and then stacking them layer by layer in the order of decreasing glass fiber material content and increasing modified material content. After molding, a composite material green body is obtained; the composite material green body is cut using CAD / CAM according to the designed implant model to obtain the biomimetic polyetheretherketone dental implant. The present invention provides a precise biomimetic polyetheretherketone dental implant material with mechanical and aesthetic gradual changes from the neck to the root and having osteogenic and antibacterial properties.

Description

Technical Field

[0001] The present invention relates to the technical field of biomedical materials, and particularly to a bionic polyetheretherketone dental implant material and a preparation method thereof. Background Art

[0002] At present, pure titanium and titanium alloys are the most commonly used implant materials. Their advantages are good wear resistance, corrosion resistance, cell and tissue compatibility. Besides the implant field, they are also widely used in orthopedic implants and other aspects. However, the elastic modulus of titanium and titanium alloys (110 GPa) is significantly higher than that of human bone (0.02 - 20 GPa), which is not matched with the elastic modulus of natural alveolar bone, resulting in stress shielding, and easily leading to mechanical complications such as occlusal stress concentration in local areas, rapid absorption of the surrounding jawbone or fracture of the implant, resulting in implant failure.

[0003] Polyetheretherketone (PEEK) is a high-performance engineering plastic. Due to its excellent mechanical properties, heat resistance and biocompatibility, it is widely used in the medical field, especially in orthopedic and dental implants. PEEK has a similar elastic modulus to human bone, with good mechanical properties, wear resistance and biocompatibility. It is a biocompatible implant material certified by the FDA and is an ideal bone substitute. However, PEEK is a hydrophobic material with biological and chemical inertness, which has disadvantages in bone bonding, restricting its further application. Although the elastic modulus of PEEK implant materials is similar to that of human bone, there are deficiencies in mechanical strength, biocompatibility and antibacterial properties, and it is difficult to meet the various requirements in the complex oral environment at the same time. In addition, the natural alveolar bone gradually transitions from cortical bone to cancellous bone from the crown to the root, and the elastic modulus gradually decreases. The functions of the implant in the vertical direction are different. The neck is the main part that bears the force, and it is necessary to match the elastic modulus with the surrounding alveolar bone to prevent stress shielding; the bottom needs to form good bone bonding with the surrounding alveolar bone to stabilize the implant. The current dental implant is a uniform modulus implant, which fails to accurately bionically simulate the structural, functional and aesthetic gradients from the neck to the root.

[0004] Therefore, providing a bionic dental implant with antibacterial properties, mechanical (elastic modulus) and aesthetic gradients from the neck to the root, and having osteogenic and antibacterial properties is an urgent problem to be solved at present. Summary of the Invention

[0005] The purpose of the present invention is to provide a bionic polyetheretherketone dental implant material and a preparation method thereof to solve the problem that the existing dental implants fail to accurately bionically simulate the structural, functional and aesthetic gradients from the neck to the root.

[0006] To achieve the above invention purpose, the present invention provides the following technical solutions:

[0007] The present invention provides a method for preparing a bionic polyetheretherketone dental implant material, comprising the following steps:

[0008] Mix the first polyetheretherketone and the first glass fiber in the first ethanol for the first mixing. After the first mixing is completed, perform the first drying to obtain the first composite powder; the content of the first glass fiber in the first composite powder is 15 wt%.

[0009] Mix the second polyetheretherketone, the second glass fiber and the second modification material in the second ethanol for the second mixing. After the second mixing is completed, perform the second drying to obtain the second composite powder; the content of the second glass fiber in the second composite powder is 12 wt%; the content of the second modification material in the second composite powder is 0.4 wt%.

[0010] Mix the third polyetheretherketone, the third glass fiber and the third modification material in the third ethanol for the third mixing. After the third mixing is completed, perform the third drying to obtain the third composite powder; the content of the third glass fiber in the third composite powder is 9 wt%; the content of the third modification material in the third composite powder is 0.8 wt%.

[0011] Mix the fourth polyetheretherketone, the fourth glass fiber and the fourth modification material in the fourth ethanol for the fourth mixing. After the fourth mixing is completed, perform the fourth drying to obtain the fourth composite powder; the content of the fourth glass fiber in the fourth composite powder is 6 wt%; the content of the fourth modification material in the fourth composite powder is 1.2 wt%.

[0012] Mix the fifth polyetheretherketone, the fifth glass fiber and the fifth modification material in the fifth ethanol for the fifth mixing. After the fifth mixing is completed, perform the fifth drying to obtain the fifth composite powder; the content of the fifth glass fiber in the fifth composite powder is 3 wt%; the content of the fifth modification material in the fifth composite powder is 1.6 wt%.

[0013] Mix the sixth polyetheretherketone and the sixth modification material in the sixth ethanol for the sixth mixing. After the sixth mixing is completed, perform the sixth drying to obtain the sixth composite powder; the content of the sixth modification material in the sixth composite powder is 2 wt%.

[0014] Press the first composite powder, the second composite powder, the third composite powder, the fourth composite powder, the fifth composite powder, and the sixth composite powder respectively to obtain the first composite powder disk, the second composite powder disk, the third composite powder disk, the fourth composite powder disk, the fifth composite powder disk, and the sixth composite powder disk;

[0015] Stack the first composite powder disk, the second composite powder disk, the third composite powder disk, the fourth composite powder disk, the fifth composite powder disk, and the sixth composite powder disk layer by layer from top to bottom, and perform vacuum hot pressing to obtain a polyetheretherketone composite green body;

[0016] Design a digital model of a dental implant, then perform functional modeling to obtain an implant model. According to the designed implant model, use CAD / CAM to cut the green body of the polyetheretherketone composite material to obtain a bionic polyetheretherketone dental implant material;

[0017] The second modifier, the third modifier, the fourth modifier, the fifth modifier, and the sixth modifier are independently maxene, silicene, two-dimensional MOF, black phosphorus, metal oxide, or transition metal sulfide.

[0018] Preferably, in the above method for preparing a bionic polyetheretherketone dental implant material, the D of the first polyetheretherketone, the second polyetheretherketone, the third polyetheretherketone, the fourth polyetheretherketone, the fifth polyetheretherketone, and the sixth polyetheretherketone 50 is independently 30 - 80 μm.

[0019] Preferably, in the above method for preparing a bionic polyetheretherketone dental implant material, the diameters of the first glass fiber, the second glass fiber, the third glass fiber, the fourth glass fiber, and the fifth glass fiber are independently 5 - 20 μm; the lengths of the first glass fiber, the second glass fiber, the third glass fiber, the fourth glass fiber, and the fifth glass fiber are independently 50 - 200 μm.

[0020] Preferably, in the above method for preparing a bionic polyetheretherketone dental implant material, the temperatures of the first mixing, the second mixing, the third mixing, the fourth mixing, the fifth mixing, and the sixth mixing are independently 20 - 30 °C, and the times of the first mixing, the second mixing, the third mixing, the fourth mixing, the fifth mixing, and the sixth mixing are independently 1 - 3 h.

[0021] Preferably, in the above method for preparing a bionic polyetheretherketone dental implant material, the thicknesses of the first composite powder disk, the second composite powder disk, the third composite powder disk, the fourth composite powder disk, the fifth composite powder disk, and the sixth composite powder disk are independently 2 - 4 mm.

[0022] Preferably, in the above method for preparing a bionic polyetheretherketone dental implant material, the temperature of the vacuum hot pressing is 350 - 380 °C, and the time of the vacuum hot pressing is 0.5 - 1 h.

[0023] The present invention also provides a bionic polyetheretherketone dental implant material prepared by the method for preparing a bionic polyetheretherketone dental implant material.

[0024] Through the above technical solutions, compared with the prior art, the present invention has the following beneficial effects:

[0025] (1) Establish a mechanically bionic polyetheretherketone dental implant with a gradient change in elastic modulus from high to low from the neck to the root. Use glass fiber for mechanical reinforcement and a modified material for biological modification, following the order of gradually decreasing mechanics and gradually increasing bioactivity from the neck to the root.

[0026] (2) Establish an aesthetically bionic polyetheretherketone dental implant with a gradient change in color from light to dark from the neck to the root.

[0027] (3) Polyetheretherketone is a hydrophobic material, and the added modified material is a hydrophilic material. Therefore, the hydrophilicity of the modified polyetheretherketone composite material is enhanced, and the hydrophilicity gradually increases with the increase in content. Theoretically, the enhanced hydrophilicity promotes an increase in the osteogenic effect, and then establish a functionally bionic polyetheretherketone dental implant with gradually increasing hydrophilicity and osteogenesis promotion from the neck to the root.

[0028] (4) Establish an antibacterial polyetheretherketone dental implant with photothermal sterilization performance. The added biological modified material has strong absorption of near-infrared light and can convert light energy into heat energy. Irradiate the implant with 808 nm near-infrared laser for 5 minutes, and the antibacterial effect on Escherichia coli and Staphylococcus aureus increases with the increase in the content of the biological additive.

[0029] (5) The modified material added in the present invention will gradually degrade over time after the implant is implanted, forming porous polyetheretherketone, which is beneficial for the further growth of cells and improves the bone-bonding efficiency. Description of the Drawings

[0030] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for the description of the embodiments or the prior art.

[0031] Figure 1 Schematic diagram of the bionic polyetheretherketone dental implant material prepared in Example 1;

[0032] Figure 2 Hydrophilic properties of the first composite powder disk, the second composite powder disk, the third composite powder disk, the fourth composite powder disk, the fifth composite powder disk, and the sixth composite powder disk in Example 1;

[0033] Figure 3 Antibacterial properties of the first composite powder disk, the second composite powder disk, the third composite powder disk, the fourth composite powder disk, the fifth composite powder disk, and the sixth composite powder disk in Example 1. Detailed Embodiments

[0034] The present invention provides a preparation method for a bionic polyetheretherketone dental implant material, including the following steps:

[0035] Mix the first polyether ether ketone and the first glass fiber in the first ethanol, and perform the first drying after the first mixing is completed to obtain the first composite powder; the content of the first glass fiber in the first composite powder is 15 wt%;

[0036] Mix the second polyether ether ketone, the second glass fiber and the second modifying material in the second ethanol, and perform the second drying after the second mixing is completed to obtain the second composite powder; the content of the second glass fiber in the second composite powder is 12 wt%; the content of the second modifying material in the second composite powder is 0.4 wt%;

[0037] Mix the third polyether ether ketone, the third glass fiber and the third modifying material in the third ethanol, and perform the third drying after the third mixing is completed to obtain the third composite powder; the content of the third glass fiber in the third composite powder is 9 wt%; the content of the third modifying material in the third composite powder is 0.8 wt%;

[0038] Mix the fourth polyether ether ketone, the fourth glass fiber and the fourth modifying material in the fourth ethanol, and perform the fourth drying after the fourth mixing is completed to obtain the fourth composite powder; the content of the fourth glass fiber in the fourth composite powder is 6 wt%; the content of the fourth modifying material in the fourth composite powder is 1.2 wt%;

[0039] Mix the fifth polyether ether ketone, the fifth glass fiber and the fifth modifying material in the fifth ethanol, and perform the fifth drying after the fifth mixing is completed to obtain the fifth composite powder; the content of the fifth glass fiber in the fifth composite powder is 3 wt%; the content of the fifth modifying material in the fifth composite powder is 1.6 wt%;

[0040] Mix the sixth polyether ether ketone and the sixth modifying material in the sixth ethanol, and perform the sixth drying after the sixth mixing is completed to obtain the sixth composite powder; the content of the sixth modifying material in the sixth composite powder is 2 wt%;

[0041] Press the first composite powder, the second composite powder, the third composite powder, the fourth composite powder, the fifth composite powder, and the sixth composite powder respectively to obtain the first composite powder disk, the second composite powder disk, the third composite powder disk, the fourth composite powder disk, the fifth composite powder disk, and the sixth composite powder disk;

[0042] Stack the first composite powder disk, the second composite powder disk, the third composite powder disk, the fourth composite powder disk, the fifth composite powder disk, and the sixth composite powder disk layer by layer from top to bottom, and perform vacuum hot pressing to obtain a polyether ether ketone composite green body;

[0043] Design a digital model of a dental implant, then perform functional modeling to obtain an implant model. According to the designed implant model, use CAD / CAM to cut the polyetheretherketone composite green body to obtain a biomimetic polyetheretherketone dental implant material.

[0044] In the present invention, the second modification material, the third modification material, the fourth modification material, the fifth modification material, and the sixth modification material are independently preferably selected from mxene, silicene, two-dimensional MOF, black phosphorus, metal oxides, or transition metal sulfides, more preferably mxene, silicene, two-dimensional MOF, or black phosphorus, and even more preferably mxene or black phosphorus; the modification materials have antibacterial and osteogenic properties.

[0045] In the present invention, the D of the first polyetheretherketone, the second polyetheretherketone, the third polyetheretherketone, the fourth polyetheretherketone, the fifth polyetheretherketone, and the sixth polyetheretherketone 50 is independently preferably 30 - 80 μm, more preferably 40 - 60 μm, and even more preferably 50 - 55 μm.

[0046] In the present invention, the diameters of the first glass fiber, the second glass fiber, the third glass fiber, the fourth glass fiber, and the fifth glass fiber are independently preferably 5 - 20 μm, more preferably 8 - 15 μm, and even more preferably 12 - 13 μm; the lengths of the first glass fiber, the second glass fiber, the third glass fiber, the fourth glass fiber, and the fifth glass fiber are independently preferably 50 - 200 μm, more preferably 80 - 160 μm, and even more preferably 100 - 150 μm.

[0047] In the present invention, the dosage ratio of the first ethanol to the first polyetheretherketone is preferably 2 - 4 mL:1 g, more preferably 2.5 - 3.5 mL:1 g, and even more preferably 2.8 - 3 mL:1 g.

[0048] In the present invention, the dosage ratio of the second ethanol to the second polyetheretherketone is preferably 2 - 4 mL:1 g, more preferably 2.5 - 3.5 mL:1 g, and even more preferably 2.8 - 3 mL:1 g.

[0049] In the present invention, the dosage ratio of the third ethanol to the third polyetheretherketone is preferably 2 - 4 mL:1 g, more preferably 2.5 - 3.5 mL:1 g, and even more preferably 2.8 - 3 mL:1 g.

[0050] In the present invention, the dosage ratio of the fourth ethanol to the fourth polyetheretherketone is preferably 2 - 4 mL:1 g, more preferably 2.5 - 3.5 mL:1 g, and even more preferably 2.8 - 3 mL:1 g.

[0051] In the present invention, the dosage ratio of the fifth ethanol to the fifth polyether ether ketone is preferably 2 - 4 mL:1 g, more preferably 2.5 - 3.5 mL:1 g, and even more preferably 2.8 - 3 mL:1 g.

[0052] In the present invention, the dosage ratio of the sixth ethanol to the sixth polyether ether ketone is preferably 2 - 4 mL:1 g, more preferably 2.5 - 3.5 mL:1 g, and even more preferably 2.8 - 3 mL:1 g.

[0053] In the present invention, the temperature of the first mixing, second mixing, third mixing, fourth mixing, fifth mixing, and sixth mixing is preferably 20 - 30 °C, more preferably 22 - 28 °C, and even more preferably 24 - 25 °C; the mixing time is preferably 1 - 3 h, more preferably 1.5 - 2.5 h, and even more preferably 2 h.

[0054] In the present invention, after the first mixing, second mixing, third mixing, fourth mixing, fifth mixing, and sixth mixing, it independently further includes: filtration.

[0055] In the present invention, the temperature of the first drying, second drying, third drying, fourth drying, fifth drying, and sixth drying is independently preferably 60 - 80 °C, more preferably 65 - 75 °C, and even more preferably 68 - 70 °C; the time of the first drying, second drying, third drying, fourth drying, fifth drying, and sixth drying is independently preferably 3 - 5 h, more preferably 3.5 - 4.5 h, and even more preferably 4 h.

[0056] In the present invention, the thickness of the first composite powder disk, second composite powder disk, third composite powder disk, fourth composite powder disk, fifth composite powder disk, and sixth composite powder disk is independently preferably 2 - 4 mm, more preferably 2.5 - 3.5 mm, and even more preferably 3 mm.

[0057] In the present invention, the temperature of the vacuum hot pressing is preferably 350 - 380 °C, more preferably 360 - 370 °C, and even more preferably 350 °C; the time of the vacuum hot pressing is preferably 0.5 - 1 h, more preferably 0.5 - 0.75 h, and even more preferably 0.5 h.

[0058] The present invention also provides a bionic polyether ether ketone dental implant prepared by the preparation method of the bionic polyether ether ketone dental implant.

[0059] Next, the technical solutions in the embodiments of the present invention will be described clearly and completely. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without making creative efforts belong to the scope of protection of the present invention.

[0060] In Example 1 below, the D of the polyetheretherketone powder 50 is 50 μm; the diameter of the glass fiber is 5 μm, and the length of the glass fiber is 80 μm; the MXene (Ti3C2T X ) flakes are purchased from Xianfeng Nano, CAS: 12363-89-2.

[0061] In Example 2 below, the D of the polyetheretherketone powder 50 is 60 μm; the diameter of the glass fiber is 12 μm, and the length of the glass fiber is 120 μm; the black phosphorus flakes are purchased from Xianfeng Nano, CAS: 7723-14-0.

[0062] Example 1

[0063] 100 g of polyetheretherketone powder and glass fibers are mixed in 200 mL of ethanol, magnetically stirred at 25 °C for 2 h, then filtered and dried at 70 °C for 4 h to obtain the first composite powder; the content of glass fibers in the first composite powder is 15 wt%;

[0064] 100 g of polyetheretherketone powder, glass fibers, and MXene (Ti3C2T X ) flakes are mixed in 200 mL of ethanol, magnetically stirred at 25 °C for 2 h, then filtered and dried at 70 °C for 4 h to obtain the second composite powder; the content of glass fibers in the second composite powder is 12 wt%; the content of MXene (Ti3C2T X ) flakes in the second composite powder is 0.4 wt%;

[0065] 100 g of polyetheretherketone powder, glass fibers, and MXene (Ti3C2T X ) flakes are mixed in 200 mL of ethanol, magnetically stirred at 25 °C for 2 h, then filtered and dried at 70 °C for 4 h to obtain the third composite powder; the content of glass fibers in the third composite powder is 9 wt%; the content of MXene (Ti3C2T X ) flakes in the third composite powder is 0.8 wt%;

[0066] 100 g of polyetheretherketone powder, glass fibers, and MXene (Ti3C2T X ) flakes are mixed in 200 mL of ethanol, magnetically stirred at 25 °C for 2 h, then filtered and dried at 70 °C for 4 h to obtain the fourth composite powder; the content of glass fibers in the fourth composite powder is 6 wt%; the content of MXene (Ti3C2T X ) flakes in the fourth composite powder is 1.2 wt%;

[0067] 100 g of polyetheretherketone powder, glass fibers, and MXene (Ti3C2T X) The flakes were mixed in 200 mL of ethanol, magnetically stirred at 25 °C for 2 h, filtered, and dried at 70 °C for 4 h to obtain the fifth composite powder; the content of glass fiber in the fifth composite powder was 3 wt%; the content of MXene (Ti3C2T X ) flakes in the fifth composite powder was 1.6 wt%;

[0068] 100 g of polyetheretherketone powder and MXene (Ti3C2T X ) flakes were mixed in 200 mL of ethanol, magnetically stirred at 25 °C for 2 h, filtered, and dried at 70 °C for 4 h to obtain the sixth composite powder; the content of MXene (Ti3C2T X ) flakes in the sixth composite powder was 2 wt%;

[0069] The first composite powder disk, the second composite powder disk, the third composite powder disk, the fourth composite powder disk, the fifth composite powder disk, and the sixth composite powder disk with a thickness of 3 mm were obtained by pressing the first composite powder, the second composite powder, the third composite powder, the fourth composite powder, the fifth composite powder, and the sixth composite powder respectively;

[0070] The first composite powder disk, the second composite powder disk, the third composite powder disk, the fourth composite powder disk, the fifth composite powder disk, and the sixth composite powder disk were stacked layer by layer in sequence, with the sixth composite powder disk at the bottom layer and the first composite powder disk at the top layer, and then vacuum hot-pressed at 350 °C for 30 min to obtain a polyetheretherketone composite green body;

[0071] A digital model of a dental implant was designed, and then a function model was established to obtain an implant model. The polyetheretherketone composite green body was machined using CAD / CAM according to the designed implant model to obtain a biomimetic polyetheretherketone dental implant material.

[0072] The schematic diagram of the biomimetic polyetheretherketone dental implant material prepared in Example 1 is as shown in Figure 1 . As can be seen from 1, it is a biomimetic polyetheretherketone dental implant material with a gradient change in color from light to deep from the neck to the root.

[0073] The hydrophilic properties of the first composite powder disk, the second composite powder disk, the third composite powder disk, the fourth composite powder disk, the fifth composite powder disk, and the sixth composite powder disk in Example 1 are as shown in Figure 2 . As can be seen from Figure 2 , polyetheretherketone is a hydrophobic material, MXene is a hydrophilic material, and the hydrophilicity of the modified polyetheretherketone composite is enhanced, and the hydrophilicity gradually increases with the increase of the MXene content. Theoretically, the enhanced hydrophilicity will also increase the osteogenic effect.

[0074] In Example 1, the antibacterial properties of the first composite powder disk, the second composite powder disk, the third composite powder disk, the fourth composite powder disk, the fifth composite powder disk, and the sixth composite powder disk are as follows Figure 3 as shown. From Figure 3 it can be seen that when the implant material is irradiated with 808 nm near-infrared laser for 5 min, the antibacterial effects on Escherichia coli and Staphylococcus aureus increase with the increase in the content of the biological additive.

[0075] Example 2

[0076] 100 g of polyetheretherketone powder and glass fiber are mixed in 250 mL of ethanol, magnetically stirred at 25 °C for 2 h, then filtered and dried at 70 °C for 4 h to obtain the first composite powder; the content of glass fiber in the first composite powder is 15 wt%.

[0077] 100 g of polyetheretherketone powder, glass fiber, and black phosphorus are mixed in 250 mL of ethanol, magnetically stirred at 25 °C for 2 h, then filtered and dried at 70 °C for 4 h to obtain the second composite powder; the content of glass fiber in the second composite powder is 12 wt%; the content of black phosphorus in the second composite powder is 0.4 wt%.

[0078] 100 g of polyetheretherketone powder, glass fiber, and black phosphorus are mixed in 250 mL of ethanol, magnetically stirred at 25 °C for 2 h, then filtered and dried at 70 °C for 4 h to obtain the third composite powder; the content of glass fiber in the third composite powder is 9 wt%; the content of black phosphorus in the third composite powder is 0.8 wt%.

[0079] 100 g of polyetheretherketone powder, glass fiber, and black phosphorus are mixed in 250 mL of ethanol, magnetically stirred at 25 °C for 2 h, then filtered and dried at 70 °C for 4 h to obtain the fourth composite powder; the content of glass fiber in the fourth composite powder is 6 wt%; the content of black phosphorus in the fourth composite powder is 1.2 wt%.

[0080] 100 g of polyetheretherketone powder, glass fiber, and black phosphorus are mixed in 250 mL of ethanol, magnetically stirred at 25 °C for 2 h, then filtered and dried at 70 °C for 4 h to obtain the fifth composite powder; the content of glass fiber in the fifth composite powder is 3 wt%; the content of black phosphorus in the fifth composite powder is 1.6 wt%.

[0081] 100 g of polyetheretherketone powder and black phosphorus are mixed in 250 mL of ethanol, magnetically stirred at 25 °C for 2 h, then filtered and dried at 70 °C for 4 h to obtain the sixth composite powder; the content of black phosphorus in the sixth composite powder is 2 wt%.

[0082] The first composite powder, the second composite powder, the third composite powder, the fourth composite powder, the fifth composite powder, and the sixth composite powder are respectively pressed to obtain a first composite powder disk with a thickness of 3 mm, a second composite powder disk with a thickness of 3 mm, a third composite powder disk with a thickness of 3 mm, a fourth composite powder disk with a thickness of 3 mm, a fifth composite powder disk with a thickness of 3 mm, and a sixth composite powder disk with a thickness of 3 mm;

[0083] The first composite powder disk, the second composite powder disk, the third composite powder disk, the fourth composite powder disk, the fifth composite powder disk, and the sixth composite powder disk are stacked layer by layer in sequence, with the sixth composite powder disk at the bottom layer and the first composite powder disk at the top layer, and then vacuum hot pressing is carried out at 360 °C for 40 min to obtain a polyetheretherketone composite green body;

[0084] A digital model of a dental implant is designed, and then a function model is established to obtain an implant model. The polyetheretherketone composite green body is cut using CAD / CAM according to the designed implant model to obtain a bionic polyetheretherketone dental implant material.

[0085] The above is only the preferred embodiment of the present invention. It should be pointed out that for those of ordinary skill in the art, without departing from the principle of the present invention, several improvements and modifications can be made, and these improvements and modifications should also be regarded as the protection scope of the present invention.

Claims

1. A preparation method of a bionic polyetheretherketone dental implant material, characterized in that, It includes the following steps: Mix the first polyether ether ketone and the first glass fiber in the first ethanol for the first mixing. After the first mixing is completed, perform the first drying to obtain the first composite powder. The content of the first glass fiber in the first composite powder is 15 wt%; Mix the second polyether ether ketone, the second glass fiber and the second modification material in the second ethanol for the second mixing. After the second mixing is completed, perform the second drying to obtain the second composite powder. The content of the second glass fiber in the second composite powder is 12 wt%; the content of the second modification material in the second composite powder is 0.4 wt%; Mix the third polyether ether ketone, the third glass fiber and the third modification material in the third ethanol for the third mixing. After the third mixing is completed, perform the third drying to obtain the third composite powder. The content of the third glass fiber in the third composite powder is 9 wt%; the content of the third modification material in the third composite powder is 0.8 wt%; Mix the fourth polyether ether ketone, the fourth glass fiber and the fourth modification material in the fourth ethanol for the fourth mixing. After the fourth mixing is completed, perform the fourth drying to obtain the fourth composite powder. The content of the fourth glass fiber in the fourth composite powder is 6 wt%; the content of the fourth modification material in the fourth composite powder is 1.2 wt%; Mix the fifth polyether ether ketone, the fifth glass fiber and the fifth modification material in the fifth ethanol for the fifth mixing. After the fifth mixing is completed, perform the fifth drying to obtain the fifth composite powder. The content of the fifth glass fiber in the fifth composite powder is 3 wt%; the content of the fifth modification material in the fifth composite powder is 1.6 wt%; Mix the sixth polyether ether ketone and the sixth modification material in the sixth ethanol for the sixth mixing. After the sixth mixing is completed, perform the sixth drying to obtain the sixth composite powder. The content of the sixth modification material in the sixth composite powder is 2 wt%; Press the first composite powder, the second composite powder, the third composite powder, the fourth composite powder, the fifth composite powder, and the sixth composite powder respectively to obtain the first composite powder disk, the second composite powder disk, the third composite powder disk, the fourth composite powder disk, the fifth composite powder disk, and the sixth composite powder disk; Stack the first composite powder disk, the second composite powder disk, the third composite powder disk, the fourth composite powder disk, the fifth composite powder disk, and the sixth composite powder disk layer by layer from top to bottom and perform vacuum hot pressing to obtain a polyether ether ketone composite green body; Design a digital model of a dental implant, then perform function modeling to obtain an implant model, and machine the polyether ether ketone composite green body according to the designed implant model using CAD / CAM to obtain a biomimetic polyether ether ketone dental implant material; The second modification material, the third modification material, the fourth modification material, the fifth modification material, and the sixth modification material are independently maxene, silicene, two-dimensional MOF, black phosphorus, metal oxide or transition metal sulfide.

2. The preparation method of the bionic polyetheretherketone dental implant material according to claim 1, characterized in that, The D of the first polyetheretherketone, the second polyetheretherketone, the third polyetheretherketone, the fourth polyetheretherketone, the fifth polyetheretherketone, and the sixth polyetheretherketone 50 independently is 30 to 80 μm.

3. The preparation method of the bionic polyetheretherketone dental implant material according to claim 2, characterized in that, The diameters of the first glass fiber, the second glass fiber, the third glass fiber, the fourth glass fiber, and the fifth glass fiber are independently 5 - 20 μm; the lengths of the first glass fiber, the second glass fiber, the third glass fiber, the fourth glass fiber, and the fifth glass fiber are independently 50 - 200 μm.

4. The preparation method of the bionic polyetheretherketone dental implant material according to claim 3, wherein, The temperatures of the first mixing, second mixing, third mixing, fourth mixing, fifth mixing, and sixth mixing are independently 20 to 30 °C, and the times of the first mixing, second mixing, third mixing, fourth mixing, fifth mixing, and sixth mixing are independently 1 to 3 h.

5. The preparation method of the bionic polyetheretherketone dental implant material according to claim 3 or 4, characterized in that, The thicknesses of the first composite powder disk, second composite powder disk, third composite powder disk, fourth composite powder disk, fifth composite powder disk, and sixth composite powder disk are independently 2 to 4 mm.

6. The preparation method of the bionic polyetheretherketone dental implant material according to claim 5, characterized in that, The temperature of the vacuum hot pressing is 350 to 380 °C, and the time of the vacuum hot pressing is 0.5 to 1 h.

7. The bionic polyetheretherketone dental implant material prepared by the preparation method of the bionic polyetheretherketone dental implant material according to any one of claims 1 to 6.

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