Soft fog inhalation device control method and device, soft fog inhalation device and storage medium

Abstract

The invention discloses a soft fog inhaler control method and device, a soft fog inhaling device and a storage medium, the method comprises the steps that physical parameters of the soft fog inhaling device are obtained, and the physical parameters comprise the maximum dosage of output single medicine and the maximum flow speed of the output medicine; the single-time medicament dosage of the user in the current period is obtained, and the single-time medicament dosage of the user is smaller than the maximum output single-time medicament dosage; and adjusting the dosage output by the soft fog inhalation device at this time to be equal to the single dosage according to the single dosage of the user. In addition, according to the soft fog inhaler, the ventilation area adjustment amount and the ventilation change threshold value can be compared according to the physical parameters of the soft fog inhaler, the next period is selected to be directly entered according to the size relation, or the ventilation opening area of the next period is adjusted according to the ventilation area adjustment amount, or the soft fog inhaler stops working and gives an alarm. The gas delivery amount of each period can be accurately controlled, and the treatment effect is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of soft mist inhalation devices, and in particular to a soft mist inhalation device control method, device, soft mist inhalation device and storage medium. Background Art

[0002] There are three main types of inhalation preparations available on the market: (1) Metered-dose inhalation aerosol (PMDI). The drug content of this type of aerosol is clear and marked with the drug dosage for each use of the metered-dose inhalation aerosol. Each use of the drug dosage is driven by a pump to deliver a fixed amount of drug. Metered-dose inhalation aerosols have their own advantages, which can ensure accurate drug dosage and are convenient for patients to use. (2) Dry powder inhaler (MDI). Dry powder inhalers help patients inhale drugs and achieve therapeutic effects by delivering drugs in the form of dry powder into the patient's respiratory tract. The main feature of dry powder inhalers is that the drugs are stored in the form of dry powder and do not require the use of liquid or gas drive devices. (3) Soft mist inhaler (SMI). Soft mist inhaler is a new type of inhalation preparation. On the one hand, it uses the mechanical energy generated by the compressed spring as a power source to provide energy for the drug to release aerosol. On the other hand, it uses the precise quantitative measurement of capillaries and the unique principle of two beams of drug liquid jets colliding at a specific angle to form a unique "soft mist".

[0003] Inhalation therapy is a process in which drugs are formed into aerosols through an inhalation device and inhaled into the airway by the patient to exert a therapeutic effect. Compared with oral and intravenous administration, it allows drugs to act directly on the respiratory mucosa and alveoli, and has the advantages of rapid onset, good efficacy, small dosage, good safety and ease of use. Therefore, inhaled drugs are the best choice for the treatment of chronic airway diseases. The correct use of the inhalation device is related to the efficacy and therapeutic effect of the drug, and is generally affected by the following factors: 1. Inspiratory flow rate: When using DPI, the inspiratory volume and inspiratory flow rate will affect the particle size and movement speed of the output drug, so you need to inhale quickly and forcefully. When the inspiratory flow rate is low, you should choose an active spray inhalation device, such as a soft mist inhaler. 2. Breathing pattern: The wrong breathing pattern will affect the deposition of aerosols in the lower respiratory tract. For example, some patients cannot fully exhale before inhaling the drug, which will affect the deposition of the drug. 3. Breath holding ability: Holding your breath after inhaling the drug is conducive to the deposition of the drug in the small airways. You need to hold your breath for 10 seconds after inhalation. 4. Limb and hand function: Patients must have good upper limb and hand functions and hand-mouth-eye coordination to complete multiple steps of inhalation therapy. The single dose and total dose of existing soft mist inhalers have been set, and users cannot adjust the dose by themselves, and cannot adjust the dose according to their own conditions. There is no monitoring device in the ventilation pipeline and flow channel of existing soft mist inhalers, and the flow change of the drug after soft atomization is more than ten times the gas flow. The respiratory flow generally depends on the patient's breathing habits. Too much flow will cause difficulty in inhalation and discomfort for the patient, and too little flow will affect the efficacy of the drug. Summary of the invention

[0004] The present invention provides a soft mist inhalation device control method, device, soft mist inhalation device and storage medium to solve the problem that the soft mist inhalation device cannot dynamically adjust the drug dosage according to the user's breathing habits.

[0005] In a first aspect, in order to solve the above technical problems, the present invention provides a method for controlling a soft mist inhalation device, comprising: Acquiring physical parameters of the soft mist inhalation device, wherein the physical parameters include a maximum single dose of medicament output and a maximum flow rate of the output medicament; Obtaining a single dose of medication of a user in a current cycle, wherein the single dose of medication of the user is less than a maximum single dose of medication output; and According to the single dose of medicine of the user, the dose of medicine outputted by the soft mist inhalation device this time is adjusted to be equal to the single dose of medicine.

[0006] In an optional embodiment, the soft mist inhalation device includes a medicine bottle, an energy storage module, a pipette, a flow control valve, a nozzle, a nozzle outlet, a nozzle, an air inlet and a delivery channel; The medicine bottle is installed inside the device; one end of the pipette is inserted into the medicine bottle, and the other end is used to connect with one end of the flow control valve, the other end of the flow control valve is connected to one end of the delivery channel, the other end of the delivery channel is connected to the inlet of the nozzle, the nozzle outlet is connected to the suction nozzle, and the suction nozzle is connected to the air inlet; The energy storage device is configured so that when a user operates the energy storage device, the medicine in the medicine bottle enters the pipette, which is a medicine loading state.

[0007] In an optional embodiment, the flow control valve includes a flow sensor; The step of adjusting the amount of medicine outputted by the soft mist inhalation device this time to be equal to the single amount of medicine comprises: Calculating a first time according to the single dose of medicine and the maximum flow rate of the output medicine; In the current cycle, the interval time between opening and closing of the flow control valve is controlled so that the interval time is equal to the first time.

[0008] In an optional embodiment, the physical parameter further includes an initial air inlet area of ​​the suction nozzle; The control method comprises: Obtaining an initial air inlet area of ​​the soft mist inhalation device, and setting a cycle time and a first ventilation change threshold and a second ventilation change threshold; wherein the first ventilation change threshold is less than the second ventilation change threshold; Acquire the user's respiratory airflow pressure in the current cycle, and calculate the average respiratory resistance according to the respiratory airflow pressure; Calculating a safe ventilation area of ​​the air inlet in the current cycle according to the average respiratory resistance; Calculating, according to the safety ventilation area, the ventilation area adjustment amount of the air inlet in the current cycle; Determine the relationship between the ventilation area adjustment amount and the first ventilation change threshold and the second ventilation change threshold; if the ventilation area adjustment amount is less than the first ventilation change threshold, directly enter the next cycle; if the ventilation area adjustment amount is greater than the first ventilation change threshold and less than the second ventilation change threshold, adjust the air inlet area of ​​the next cycle according to the ventilation area adjustment amount, and enter the next cycle; if the ventilation area adjustment amount is greater than the second ventilation change threshold, control the soft mist inhalation device to stop working and issue an alarm.

[0009] In an optional implementation, the acquiring of the user's respiratory airflow pressure in the current cycle and calculating the average respiratory resistance according to the respiratory airflow pressure includes: Acquire the breathing airflow pressure of the user; wherein the breathing airflow pressure includes the airflow pressure when the user inhales and the airflow pressure when the user exhales; Counting the number of breaths of the user in the said cycle; The average respiratory resistance is calculated according to the respiratory airflow pressure and the number of breaths.

[0010] In an optional implementation, calculating the safe ventilation area of ​​the air inlet in the current cycle according to the average respiratory resistance includes: The safe ventilation area is calculated according to the following formula: in, represents the safe ventilation area, represents the maximum flow rate of the output medicine, represents the initial air inlet area, represents the average respiratory resistance.

[0011] In an optional implementation manner, the calculating, according to the safety ventilation area, the ventilation area adjustment amount of the air inlet in the current cycle includes: The ventilation area adjustment amount is calculated according to the following formula: in, represents the ventilation area adjustment amount, represents the safe ventilation area, represents the maximum flow rate of the output medicine, represents the initial air inlet area.

[0012] In an optional embodiment, if the ventilation area adjustment amount is greater than the first ventilation change threshold but less than the second ventilation change threshold, adjusting the air inlet area of ​​the next cycle according to the ventilation area adjustment amount includes: Calculating the air inlet area of ​​the next cycle according to the ventilation area adjustment amount; Adjusting the air inlet so that the air inlet area of ​​the current cycle becomes the air inlet area of ​​the next cycle; The air inlet area of ​​the next cycle is calculated according to the following formula: in, represents the air inlet area of ​​the next cycle, represents the ventilation area adjustment amount, represents the initial air inlet area.

[0013] In an optional implementation, the calculating the average respiratory resistance according to the respiratory airflow pressure and the number of breaths includes: The average respiratory resistance is calculated according to the following formula, in, represents the average respiratory resistance, Indicates the time it takes for the user to take a breath. represents the cycle time, represents the number of breaths, represents the respiratory airflow pressure.

[0014] In a second aspect, the present invention provides a control device for a soft mist inhalation device, comprising: The first acquisition module is used to acquire physical parameters of the soft mist inhalation device, and the physical parameters include the maximum dose of a single dose of medicine output and the maximum flow rate of the output medicine; the second acquisition module is used to acquire the single dose of medicine of the user in the current cycle, and the single dose of medicine of the user is less than the maximum dose of a single dose of medicine output; and the adjustment module is used to adjust the dose of medicine output by the soft mist inhalation device this time to be equal to the single dose of medicine according to the single dose of medicine of the user.

[0015] In a third aspect, the present invention also provides a soft mist inhalation device, comprising a processor, a memory, and a computer program stored in the memory and configured to be executed by the processor, wherein when the processor executes the computer program, the soft mist inhalation device control method described in any one of the above is implemented.

[0016] In a fourth aspect, the present invention also provides a computer-readable storage medium, which includes a stored computer program, wherein when the computer program is running, the device where the computer-readable storage medium is located is controlled to execute any one of the soft mist inhalation device control methods described above.

[0017] Compared with the prior art, the present invention has the following beneficial effects: The present invention provides a control method for a soft mist inhalation device, comprising obtaining an initial air inlet area and a maximum flow rate of an output medicine of the soft mist inhalation device, and setting a cycle time and a first ventilation change threshold and a second ventilation change threshold; wherein the first ventilation change threshold is less than the second ventilation change threshold; obtaining a user's respiratory airflow pressure in a current cycle, and calculating an average respiratory resistance according to the respiratory airflow pressure; calculating a safe ventilation area of ​​the air inlet in the current cycle according to the average respiratory resistance; calculating a ventilation area adjustment amount of the air inlet in the current cycle according to the safe ventilation area; judging a size relationship between the ventilation area adjustment amount and the first ventilation change threshold and the second ventilation change threshold; if the ventilation area adjustment amount is less than the first ventilation change threshold, directly entering the next cycle; if the ventilation area adjustment amount is greater than the first ventilation change threshold and less than the second ventilation change threshold, adjusting the air inlet area of ​​the next cycle according to the ventilation area adjustment amount, and entering the next cycle; if the ventilation area adjustment amount is greater than the second ventilation change threshold, controlling the soft mist inhalation device to stop working and sounding an alarm.

[0018] The method obtains the patient's respiratory airflow pressure in the current cycle, calculates the required ventilation area adjustment amount, and determines whether to adjust the air inlet area of ​​the next cycle or issue an alarm based on the size relationship between the ventilation area adjustment amount and a preset threshold value, thereby controlling the drug dosage released by the soft mist inhalation device, thereby accurately controlling the gas delivery amount in each cycle and achieving the best treatment effect for the patient. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 is a flow chart of a method for controlling a soft mist inhalation device provided by an embodiment of the present invention; Figure 2 is a schematic structural diagram of a soft mist inhalation device provided by an embodiment of the present invention; Figure 3 It is a schematic flow chart of a control method of a soft mist inhalation device provided by a first embodiment of the present invention; Figure 4 is a schematic flow chart of another method for controlling a soft mist inhalation device provided by an embodiment of the present invention; Figure 5 It is a schematic flow chart of another method for controlling a soft mist inhalation device provided by an embodiment of the present invention; Figure 6 is a schematic structural diagram of a control device of a soft mist inhalation device provided in a second embodiment of the present invention; Figure 7 is a schematic structural diagram of a control device of another soft mist inhalation device provided by an embodiment of the present invention; Figure 8Detailed description of the invention Figure 2 is a schematic diagram of the structure of a control device of yet another soft mist inhalation device provided in an embodiment of the present invention. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0021] like Figure 1 As shown, the present application provides a method for controlling a soft mist inhalation device, and its workflow generally may include: Acquiring physical parameters of the soft mist inhalation device, wherein the physical parameters include a maximum single dose of medicament output and a maximum flow rate of the output medicament; Obtaining a single dose of medication of a user in a current cycle, wherein the single dose of medication of the user is less than a maximum single dose of medication output; and According to the single dose of medicine of the user, the dose of medicine outputted by the soft mist inhalation device this time is adjusted to be equal to the single dose of medicine.

[0022] like Figure 2 As shown, in order to solve the influencing factor 1 of inhalation therapy in the background technology, an embodiment of the present invention provides a soft mist inhalation device, which includes a medicine bottle 1, an energy storage module 2, a pipette 3, a flow control valve 4, a nozzle 8, a nozzle outlet 7, a nozzle 9, an air inlet (5, 6) and a delivery channel 10.

[0023] The medicine bottle 9 is installed inside the device. One end of the pipette 3 is inserted into the medicine bottle 9, and the other end is used to connect with one end of the flow control valve 3. The other end of the flow control valve 3 is connected to one end of the delivery channel 10. The other end of the delivery channel 10 is connected to the inlet of the nozzle 9. The outlet of the nozzle 9 is connected to the suction nozzle 8, and the suction nozzle 8 is connected to the air inlet (5, 6).

[0024] When the user operates the energy storage device 2 to allow the liquid in the medicine bottle 9 to enter the pipette 3, this is called the medicine loading state. The energy storage device 2 may be a spring structure, and the energy storage device 2 is configured to drive the pipette 3 to move toward the bottom of the medicine bottle 1 during the downward pressure and contraction process. Since the medicine bottle 9 and the pipette 3 are vacuum-connected, a negative pressure state is formed, and then the liquid medicine in the medicine bottle 9 enters the pipette 3.

[0025] When the user triggers the spraying state, the device controls the opening and closing time of the flow control valve 4, thereby controlling the inhaled amount of the drug sprayed by the device and the maximum flow rate of the output drug, and finally the drug is sprayed from the nozzle outlet 7 of the nozzle 9. In this way, the amount and flow rate of the drug sprayed by the soft mist inhalation device can be flexibly controlled, and different users and patients can adjust according to their own conditions.

[0026] By controlling the air flow rate of the air inlet (5, 6), the breathing pattern of the user patient (influencing factor 2) is adjusted; in this embodiment, an air inlet valve is provided at the air inlet (5, 6) to control the ventilation area of ​​the air inlet (5, 6), so that the user patient can adjust the air flow rate of the air inlet valve according to his or her own physical condition, that is, select different breathing patterns, and finally achieve effective breathing deposition efficiency.

[0027] In this embodiment, the air inlet (5, 6) can also be adjusted to a closed state after the user patient inhales the medicine, that is, the breath holding ability of the influencing factor 3 can be achieved. In this embodiment, the user can also connect the mouthpiece 8 through a breathing mask, which has a relatively small impact on the user patient's limb ability and hand function; for users with poor limb ability and hand function, the user can connect the mouthpiece 8 through a mask, pre-set the opening and closing time of the flow control valve 4, and adjust the air flow rate of the air inlet (5, 6) to achieve the optimal breathing mode. In this embodiment, during the user's breathing process, the device adjusts the ventilation area of ​​the air inlet (5, 6) in real time according to the user's breathing airflow pressure to achieve the optimal breathing mode.

[0028] The flow control valve includes a flow sensor; the step of adjusting the amount of medicine output by the soft mist inhalation device to be equal to the single amount of medicine includes: Calculating a first time according to the single dose of medicine and the maximum flow rate of the output medicine; In the current cycle, the interval time between opening and closing of the flow control valve is controlled so that the interval time is equal to the first time.

[0029] Reference Figure 3 The first embodiment of the present invention provides a control method for a soft mist inhalation device, which is used to implement the soft mist inhalation device provided by the present invention. The physical parameters include not only the maximum dosage of a single medicament output and the maximum flow rate of the output medicament, but also the initial air inlet area of ​​the nozzle. The control method includes the following steps: S1, obtaining the initial air inlet area of ​​the soft mist inhalation device, and setting a cycle time and a first ventilation change threshold and a second ventilation change threshold; wherein the first ventilation change threshold is less than the second ventilation change threshold; S2, obtaining the user's respiratory airflow pressure in the current cycle, and calculating the average respiratory resistance according to the respiratory airflow pressure; S3, calculating the safe ventilation area of ​​the air inlet in the current cycle according to the average respiratory resistance; S4, calculating the ventilation area adjustment amount of the air inlet in the current cycle according to the safety ventilation area; S5, determine the relationship between the ventilation area adjustment amount and the first ventilation change threshold and the second ventilation change threshold; if the ventilation area adjustment amount is less than the first ventilation change threshold, directly enter the next cycle; if the ventilation area adjustment amount is greater than the first ventilation change threshold and less than the second ventilation change threshold, adjust the air inlet area of ​​the next cycle according to the ventilation area adjustment amount, and enter the next cycle; if the ventilation area adjustment amount is greater than the second ventilation change threshold, control the soft mist inhalation device to stop working and issue an alarm.

[0030] It should be noted that the existing soft mist inhalation device is generally driven by a pump to administer drugs, so the overall dose of the drug released each time is quantitative. Among them, soft mist refers to aerosol preparations such as ultrasonic mist and pressure mist. This kind of soft mist inhalation device for quantitative administration does not require too much operation, and the patient can easily grasp the dosage of each medication, which is more convenient for the patient. However, the disadvantages of this quantitative soft mist inhalation device are also obvious, that is, the dosage cannot be changed dynamically and cannot be adjusted according to the actual situation of the patient. Especially for some older or younger patients, the dosage of each administration of the quantitative soft mist inhalation device may be large, and it is difficult to accurately match the treatment needs, which is not conducive to the patient's treatment effect.

[0031] In the present invention, by designing a soft mist inhalation device with an intelligent control system, the drug delivery amount of each cycle is accurately controlled, thereby solving the problem that the quantitative soft mist inhalation device is not conducive to the treatment effect of the patient. The soft mist inhalation device is equipped with a central processing unit as the core, and also includes high-precision flow sensors, large-capacity memory and flexible regulating valves and other components, which together construct an intelligent system that can monitor, analyze and respond to the patient's breathing state in real time. The intelligent system can capture each breathing action of the patient, and calculate the air inlet adjustment amount based on the average breathing resistance, so as to judge the operations required in the current cycle: maintain the current mode, calculate the appropriate air inlet area and adjust the regulating valve, and stop working and issue an alarm. At the same time, the user's breathing airflow resistance and the breathing resistance of different users are different. Therefore, in order to avoid the large noise and vibration caused by the opening of the regulating valve, and the waste of extra energy generated by the vibration, the method can eliminate the problem caused by fogging when wearing a breathing mask by setting a cycle of control, and it is also convenient for patients to control the safety of their own use, so that the drug supply and dosage can be more accurately controlled to achieve better treatment effects. The soft mist inhalation device will periodically repeat the above-mentioned control operation to ensure the purpose of real-time and intelligent control. This instant and intelligent feedback adjustment mechanism not only greatly improves the accuracy and effectiveness of drug treatment and helps patients achieve the best treatment effect, but also significantly improves the patient's use experience and reduces the discomfort and risks that may be caused by improper dosage.

[0032] In step S1, it is necessary to obtain the initial air inlet area and the maximum flow rate of the output medicine of the soft mist inhalation device, and set a cycle time and a first ventilation change threshold and a second ventilation change threshold. The above data needs to be stored in the soft mist inhalation device for subsequent calculation.

[0033] Specifically, it is first necessary to deeply analyze and comprehensively consider the physiological data and respiratory characteristics of a large number of patients, so as to design a suitable initial air inlet area and the maximum flow rate of the output medicine, and set a cycle time and a first ventilation change threshold and a second ventilation change threshold. Then, the above parameter data is stored in the memory of the soft mist inhalation device. Among them, the one cycle time represents a period of time (for example, 12 minutes) when the patient uses the soft mist inhalation device. The first ventilation change threshold represents the maximum change value of the airflow pressure generated by the patient's normal breathing in the current cycle, indicating that if the patient's average respiratory resistance is within the first ventilation change threshold, the soft mist inhalation device does not need to adjust the air inlet area. The second ventilation change threshold represents the maximum change value of the airflow pressure generated by the patient's abnormal breathing in the current cycle, indicating that if the patient's average respiratory resistance exceeds the second ventilation change threshold, the soft mist inhalation device needs to stop adjusting the air inlet and issue an abnormal alarm to notify relevant personnel to handle it.

[0034] It should be noted that the soft mist inhalation device includes a host, a breathing mask connected to the host through a connecting tube, a flow sensor and a memory arranged in the host, a central processing unit electrically connected to the flow sensor, a regulating valve connected to the central processing unit, and a stepper motor connected to the regulating valve, and an air inlet is arranged at the intersection of the connecting tube and the flow sensor. When designing and manufacturing the soft mist inhalation device, the designer needs to consider whether the above components conform to the principles of ergonomics, whether the materials used are strong and durable, whether the structure is easy to replace and maintain, and set appropriate redundancy. For example, when designing the air inlet, the diameter of the air inlet should be greater than 3 mm to ensure that the flow sensor can work normally. At the same time, given that different users may have different respiratory ventilation changes due to factors such as age, gender, disease severity, and physiological state, when setting the first ventilation change threshold and the second ventilation change threshold, it is necessary to repeatedly consider the above factors, or provide user customization options, so as to more flexibly adapt to the unique breathing pattern of each patient and achieve a more accurate and safe treatment experience.

[0035] In step S2, the soft mist inhalation device first uses the flow sensor to obtain the user's breathing airflow pressure in the current cycle, and records the number of breaths taken by the user in the current cycle. Then, the central processor is used to calculate the average breathing resistance according to the breathing airflow pressure and the number of breaths taken.

[0036] Reference Figure 4 In one embodiment, the step of obtaining the user's respiratory airflow pressure in the current cycle and calculating the average respiratory resistance according to the respiratory airflow pressure comprises the following steps: S21, the soft mist inhalation device obtains the breathing airflow pressure of the user in the current cycle.

[0037] Specifically, the soft mist inhalation device first uses a built-in flow sensor to capture and measure the user's breathing airflow pressure. The breathing airflow pressure includes the airflow pressure when the user inhales and the airflow pressure when the user exhales. Then the measured breathing airflow pressure is recorded in the memory to form a continuous and traceable record of the user's breathing state.

[0038] It should be noted that the breathing fluctuations of some users are small, and the flow sensor may not be able to accurately capture it, resulting in misjudgment. Therefore, in the process of designing the soft mist inhalation device, it is necessary to use a more accurate flow sensor or adopt a structural design that is more conducive to capturing breathing movements.

[0039] Furthermore, in order to fully reflect the user's breathing condition and potential change trends, the soft mist inhalation device needs to record the respiratory airflow pressure data within multiple continuous use cycles in the memory, so that the doctor can make more accurate and appropriate medical suggestions based on the changes in the respiratory airflow pressure data, or can promptly search the records to find out the cause after an unexpected situation occurs.

[0040] S22, the soft mist inhalation device counts the number of breaths of the user in the one cycle.

[0041] Specifically, the soft mist inhalation device analyzes the data obtained by measuring the respiratory airflow pressure, and obtains the number of breaths of the user in the cycle. The measured data is a periodic function similar to a sine function, and each cycle more accurately reflects the complete breathing process of the user from the beginning of inhalation to the end of exhalation. The soft mist inhalation device can determine a complete breathing action by obtaining the peaks (indicating the inhalation action) and troughs (indicating the exhalation action) that appear in the periodic function, thereby counting the number of breaths in a cycle and recording it in a memory.

[0042] S23, the soft mist inhalation device calculates the average respiratory resistance according to the respiratory airflow pressure and the number of breaths.

[0043] In one embodiment, the calculating the average respiratory resistance according to the respiratory airflow pressure and the number of breaths includes: The average respiratory resistance is calculated according to the following formula, in, represents the average respiratory resistance, Indicates the time it takes for the user to take a breath. represents the cycle time, represents the number of breaths, represents the respiratory airflow pressure.

[0044] Specifically, the central processor of the soft mist inhalation device first reads the preset cycle time and the number of breaths from the memory, and calculates the time for the user to take a breath. Subsequently, the central processor reads the breathing airflow pressure and the time for taking a breath, and calculates the average breathing resistance according to a preset formula. Finally, the calculated result is stored in the memory.

[0045] Furthermore, considering the possible data analysis needs in the future, if the memory of the soft mist inhalation device has sufficient capacity, the time of each breathing of the user can also be stored in the memory. The time of each breathing can help doctors make more detailed judgments and measures.

[0046] In another embodiment, the soft mist inhalation device uses a current sensor to replace the original flow sensor. The current sensor can record the current value generated by the inflow and outflow of gas during breathing, and calculate the real-time flow data of the gas based on the current value, so as to accurately judge the breathing action. The current sensor can also record very accurately when the breathing fluctuation is small.

[0047] In step S3, the safe ventilation area of ​​the air inlet in the current cycle is calculated according to the average respiratory resistance, including calculating the safe ventilation area according to the following formula: in, represents the safe ventilation area, represents the maximum flow rate of the output medicine, represents the initial air inlet area, represents the average respiratory resistance.

[0048] Specifically, the central processor first reads the average respiratory resistance, the initial air inlet area, the average respiratory resistance and the maximum flow rate of the output medicine from the memory, and then calculates the safe ventilation area using a preset formula and stores the calculated result in the memory.

[0049] In another embodiment, the soft mist inhalation device can also determine whether to maintain the safe ventilation area by the following method: an air pressure sensor capable of obtaining the internal gas pressure of the breathing mask is installed in the soft mist inhalation device; the air pressure sensor obtains the respiratory air pressure and transmits it to the central processing unit; the central processing unit converts the continuously received respiratory air pressure into a differential form according to time, and calculates the pressure difference change of the respiratory air pressure, as well as the standard value and maximum value of the pressure difference change; the central processing unit determines the size relationship between the standard value and the maximum value; when the standard value is greater than the maximum value, the current safe ventilation area can be maintained, and the current cycle is waited for to end and enter the next cycle; wherein the standard value is calculated according to the following formula, in, Indicates the standard value, Indicates the pressure inside the breathing mask at the end of inspiration. represents the constant minimum pressure difference of the respiratory airflow, Indicates the maximum absolute value of negative pressure during inhalation. Indicates the total breathing process time of the current time period. Indicates the time of a single inhalation or exhalation process.

[0050] In step S4, the ventilation area adjustment amount of the air inlet is calculated in the current cycle according to the safety ventilation area, including calculating the ventilation area adjustment amount according to the following formula: in, represents the ventilation area adjustment amount, represents the safe ventilation area, represents the maximum flow rate of the output medicine, represents the initial air inlet area.

[0051] Specifically, the central processor first reads the safety ventilation area, the maximum flow rate of the output medicine, and the initial air inlet area from the memory. Then, the central processor calculates the safety ventilation area according to the above-read data using a preset formula, and stores the calculated result in the memory.

[0052] In another embodiment, in order to realize the combination of the control of the inhalation resistance and the air inlet, the calculation method of the ventilation area adjustment amount can be replaced by the following calculation method: in, represents the ventilation area adjustment amount, represents the safe ventilation area, represents the maximum flow rate of the output medicine, represents the initial air inlet area, Represents the average breathing resistance. The algorithm optimizes the calculation method of the ventilation area adjustment amount. By introducing a more sophisticated adjustment mechanism and a more efficient calculation method, the algorithm can achieve more accurate and subtle control of the air inlet area. The algorithm not only helps to improve the user's breathing experience, but also effectively prevents potential risks caused by improper ventilation area at critical moments.

[0053] In step S5, the central processor of the soft mist inhalation device determines the magnitude relationship between the ventilation area adjustment amount and the first ventilation change threshold and the second ventilation change threshold, and performs different operations according to the determination result: In a first embodiment, if the ventilation area adjustment amount is less than the first ventilation change threshold, the soft mist inhalation device does not need to adjust the air inlet area, and only needs to wait for the timing to end and enter the next cycle.

[0054] In a second embodiment, if the ventilation area adjustment amount is greater than the first ventilation change threshold value but less than the second ventilation change threshold value, the air inlet area of ​​the next cycle is adjusted according to the ventilation area adjustment amount, such as Figure 5 As shown, it includes: calculating the air inlet area of ​​the next cycle according to the ventilation area adjustment amount; adjusting the air inlet so that the air inlet area of ​​the current cycle becomes the air inlet area of ​​the next cycle; wherein the air inlet area of ​​the next cycle is calculated according to the following formula, in, represents the air inlet area of ​​the next cycle, represents the ventilation area adjustment amount, represents the initial air inlet area.

[0055] Specifically, the central processing unit first needs to read the ventilation area adjustment amount and the current area of ​​the air inlet from the memory. Then, the central processing unit calculates the area of ​​the air inlet of the next cycle according to the ventilation area adjustment amount using a preset formula, and sends an adjustment instruction to the regulating valve. Finally, the regulating valve adjusts the area of ​​the air inlet to the area of ​​the air inlet of the next cycle. After the adjustment is completed, the timing is waited for to end and enter the next cycle.

[0056] It should be noted that the area of ​​the air inlet is adjusted by opening or closing the regulating valve. The switching state of the regulating valve has a certain position range to ensure that the air inlet can be adjusted within a safe range. Furthermore, the regulating valve is driven by a stepper motor and may produce a certain degree of vibration. Therefore, the regulating valve can be replaced by an electronic regulating valve, which can make real-time or near real-time flow area adjustments by responding to the input electrical signal of the central controller, and no vibration or very little vibration is generated during the flow area adjustment process, so that users have a better experience.

[0057] In a third embodiment, if the ventilation area adjustment amount is greater than the second ventilation change threshold, the soft mist inhalation device immediately takes emergency response measures, including stopping the adjustment of the regulating valve and recording the ventilation change amount, and issuing an alarm to notify the relevant personnel to handle it, so as to ensure the safety of the user and the stable operation of the soft mist inhalation device. Furthermore, the alarm issued by the soft mist inhalation device can be a high-brightness light, a high-decibel sound, or it can be connected to the Internet and bound to the software on the mobile phone or computer to facilitate the relevant personnel to pay attention in time.

[0058] It should be noted that when the soft mist inhalation device enters the next cycle normally, the central processor will perform self-inspection and zeroing on the air inlet and the regulating valve, and monitor the flow changes of the host in real time, so as to achieve flow control.

[0059] To facilitate understanding of the present invention, the working process of the present invention is described below using a common scenario as an example: In this embodiment, it is planned to produce a set of soft mist inhalation devices, and add an intelligent control system to the series of soft mist inhalation devices. The system is designed to intelligently control the dosage of the drug released by the soft mist inhalation device in each cycle according to the patient's breathing conditions, so as to achieve better treatment effects.

[0060] The general working process is as follows: Step 1: Obtain relevant information about the patient, design an ergonomic soft mist inhalation device, and add the required preset parameters to the soft mist inhalation device according to the situation, including the initial air inlet area, the maximum flow rate of the output medicine, a cycle time, the first ventilation change threshold, and the second ventilation change threshold.

[0061] Step 2: The patient wears the soft mist inhalation device and adjusts necessary preset parameters according to his or her own situation.

[0062] Step 3: The soft mist inhalation device obtains the patient's respiratory airflow pressure in each cycle, and calculates the average respiratory resistance according to the respiratory airflow pressure and stores it in a memory.

[0063] Step 4: The central processor of the soft mist inhalation device calculates the safe ventilation area of ​​the air inlet in each cycle according to the average respiratory resistance.

[0064] Step 5: The central processor of the soft mist inhalation device calculates the ventilation area adjustment amount of the air inlet in each cycle according to the safe ventilation area.

[0065] Step 6: The soft mist inhalation device determines the relationship between the ventilation area adjustment amount and the first ventilation change threshold and the second ventilation change threshold. If the ventilation area adjustment amount is less than the first ventilation change threshold, the next cycle is directly entered; if the ventilation area adjustment amount is greater than the first ventilation change threshold and less than the second ventilation change threshold, the air inlet area of ​​the next cycle is adjusted according to the ventilation area adjustment amount, and the next cycle is entered; if the ventilation area adjustment amount is greater than the second ventilation change threshold, the soft mist inhalation device stops working and issues an alarm.

[0066] Step 7: If the soft mist inhalation device enters the next cycle normally, steps 3 to 6 are repeated until the patient stops using the device or the soft mist inhalation device sounds an alarm.

[0067] Through the above steps, the soft mist inhalation device can timely and intelligently adjust the dosage of the released medicine according to the patient's current breathing condition, thereby improving the treatment effect.

[0068] In summary, the present invention provides a control method for a soft mist inhalation device, including obtaining an initial air inlet area and a maximum flow rate of an output agent of the soft mist inhalation device, and setting a cycle time and a first ventilation change threshold and a second ventilation change threshold; wherein the first ventilation change threshold is less than the second ventilation change threshold; obtaining the user's respiratory airflow pressure in the current cycle, and calculating the average respiratory resistance according to the respiratory airflow pressure; calculating the safe ventilation area of ​​the air inlet in the current cycle according to the average respiratory resistance; calculating the ventilation area adjustment amount of the air inlet in the current cycle according to the safe ventilation area; judging the size relationship between the ventilation area adjustment amount and the first ventilation change threshold and the second ventilation change threshold; if the ventilation area adjustment amount is less than the first ventilation change threshold, directly entering the next cycle; if the ventilation area adjustment amount is greater than the first ventilation change threshold and less than the second ventilation change threshold, adjusting the air inlet area of ​​the next cycle according to the ventilation area adjustment amount, and entering the next cycle; if the ventilation area adjustment amount is greater than the second ventilation change threshold, controlling the soft mist inhalation device to stop working and sounding an alarm. The method obtains the patient's respiratory airflow pressure in the current cycle, calculates the required ventilation area adjustment amount, and determines whether to adjust the air inlet area of ​​the next cycle or issue an alarm based on the size relationship between the ventilation area adjustment amount and a preset threshold value, thereby controlling the drug dosage released by the soft mist inhalation device, thereby accurately controlling the gas delivery volume of each cycle, so that the patient can achieve the best treatment effect and avoid harm.

[0069] Reference Figure 6 The second embodiment of the present invention provides a control device for a soft mist inhalation device, comprising: A data initialization module, used to obtain the initial air inlet area of ​​the soft mist inhalation device and the maximum flow rate of the output medicine, and set a cycle time and a first ventilation change threshold and a second ventilation change threshold; wherein the first ventilation change threshold is less than the second ventilation change threshold; Among them, the data initialization module includes a hardware data initialization module, which is used to obtain the initial air inlet area of ​​the soft mist inhalation device and the maximum flow rate of the output medicine; and a software data initialization module, which is used to obtain a preset cycle time and a first ventilation change threshold and a second ventilation change threshold.

[0070] A breathing resistance calculation module, used to obtain the user's breathing airflow pressure in the current cycle, and calculate the average breathing resistance according to the breathing airflow pressure; Among them, Figure 7As shown, the respiratory resistance calculation module includes an airflow pressure detection module, which is used to detect the change of airflow pressure during the user's breathing process; a breathing frequency statistics module, which is used to count the number of breaths of the user in the current cycle; and a resistance calculation module, which is used to calculate the average respiratory resistance based on the respiratory airflow pressure and the breathing frequency.

[0071] A safe ventilation area calculation module, used to calculate the safe ventilation area of ​​the air inlet in the current cycle according to the average respiratory resistance; Among them, the safe ventilation area calculation module includes a respiratory resistance acquisition module, which is used to obtain the average respiratory resistance and the cycle time stored in the memory; and an area calculation module, which is used to calculate the safe ventilation area of ​​the air inlet in the current cycle according to the acquired parameters.

[0072] A ventilation area adjustment amount calculation module, used to calculate the ventilation area adjustment amount of the air inlet in the current cycle according to the safety ventilation area; Among them, the ventilation area adjustment amount calculation module includes a ventilation area acquisition module, which is used to obtain the safe ventilation area and the maximum flow rate of the output agent stored in the memory; an adjustment amount calculation module, which is used to calculate the ventilation area adjustment amount of the air inlet in the current cycle according to the acquired parameters.

[0073] The ventilation area adjustment module is used to determine the size relationship between the ventilation area adjustment amount and the first ventilation change threshold and the second ventilation change threshold; if the ventilation area adjustment amount is less than the first ventilation change threshold, directly enter the next cycle; if the ventilation area adjustment amount is greater than the first ventilation change threshold and less than the second ventilation change threshold, adjust the air inlet area of ​​the next cycle according to the ventilation area adjustment amount, and enter the next cycle; if the ventilation area adjustment amount is greater than the second ventilation change threshold, control the soft mist inhalation device to stop working and issue an alarm.

[0074] Among them, Figure 8 As shown, the ventilation area adjustment module includes a threshold judgment module, which is used to judge the size relationship between the ventilation area adjustment amount and the first ventilation change threshold and the second ventilation change threshold, and take corresponding actions according to the judgment result; an area calculation module, which is used to calculate the air inlet area of ​​the next cycle according to the ventilation area adjustment amount; and an area adjustment module, which is used to control the regulating valve to make corresponding adjustments to the area of ​​the air inlet.

[0075] It should be noted that the control device of a soft mist inhalation device provided in an embodiment of the present invention is used to execute all the process steps of a soft mist inhalation device control method of the above embodiment, and the working principles and beneficial effects of the two correspond one to one, so they will not be repeated.

[0076] The embodiment of the present invention further provides a soft mist inhalation device, in which an electronic device is provided. The electronic device includes: a processor, a memory, and a computer program stored in the memory and executable on the processor, such as a control program for the soft mist inhalation device. When the processor executes the computer program, the steps in the above-mentioned soft mist inhalation device control method embodiments are implemented, such as Figure 2 Alternatively, when the processor executes the computer program, the functions of each module / unit in the above-mentioned device embodiments are realized, such as the ventilation area adjustment amount calculation module.

[0077] Exemplarily, the computer program may be divided into one or more modules / units, which are stored in the memory and executed by the processor to implement the present invention. The one or more modules / units may be a series of computer program instruction segments capable of implementing specific functions, which are used to describe the execution process of the computer program in the electronic device.

[0078] The electronic device may be a computing device such as a desktop computer, a notebook, a PDA, and a smart tablet. The electronic device may include, but is not limited to, a processor and a memory. Those skilled in the art will appreciate that the above components are merely examples of electronic devices and do not constitute a limitation on the electronic device. The electronic device may include more or fewer components than the above components, or may combine certain components, or different components. For example, the electronic device may also include input and output devices, network access devices, buses, etc.

[0079] The processor may be a central processing unit (CPU), other general-purpose processors, digital signal processors (DSP), application-specific integrated circuits (ASIC), field-programmable gate arrays (FPGA) or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components, etc. A general-purpose processor may be a microprocessor or any conventional processor, etc. The processor is the control center of the electronic device, and uses various interfaces and lines to connect various parts of the entire electronic device.

[0080] The memory can be used to store the computer program and / or module, and the processor realizes various functions of the electronic device by running or executing the computer program and / or module stored in the memory, and calling the data stored in the memory. The memory can mainly include a program storage area and a data storage area, wherein the program storage area can store an operating system, an application required for at least one function (such as a sound playback function, an image playback function, etc.), etc.; the data storage area can store data created according to the use of the mobile phone (such as audio data, a phone book, etc.), etc. In addition, the memory can include a high-speed random access memory, and can also include a non-volatile memory, such as a hard disk, a memory, a plug-in hard disk, a smart memory card (Smart Media Card, SMC), a secure digital (Secure Digital, SD) card, a flash card (Flash Card), at least one disk storage device, a flash memory device, or other volatile solid-state storage devices.

[0081] Wherein, if the module / unit integrated in the electronic device is implemented in the form of a software functional unit and sold or used as an independent product, it can be stored in a computer-readable storage medium. Based on such an understanding, the present invention implements all or part of the processes in the above-mentioned embodiment method, and can also be completed by instructing the relevant hardware through a computer program. The computer program can be stored in a computer-readable storage medium, and the computer program can implement the steps of the above-mentioned various method embodiments when executed by the processor. Wherein, the computer program includes computer program code, and the computer program code can be in source code form, object code form, executable file or some intermediate form. The computer-readable medium may include: any entity or device capable of carrying the computer program code, recording medium, U disk, mobile hard disk, disk, optical disk, computer memory, read-only memory (ROM, Read-Only Memory), random access memory (RAM, Random Access Memory), electric carrier signal, telecommunication signal and software distribution medium. It should be noted that the content contained in the computer-readable medium can be appropriately increased or decreased according to the requirements of legislation and patent practice in the jurisdiction. For example, in some jurisdictions, according to legislation and patent practice, computer-readable media do not include electric carrier signals and telecommunication signals.

[0082] It should be noted that the device embodiments described above are merely schematic, wherein the units described as separate components may or may not be physically separated, and the components displayed as units may or may not be physical units, that is, they may be located in one place, or they may be distributed on multiple network units. Some or all of the modules may be selected according to actual needs to achieve the purpose of the scheme of this embodiment. In addition, in the accompanying drawings of the device embodiments provided by the present invention, the connection relationship between the modules indicates that there is a communication connection between them, which may be specifically implemented as one or more communication buses or signal lines. A person of ordinary skill in the art may understand and implement it without paying any creative effort.

[0083] The specific embodiments described above further describe the purpose, technical solutions and beneficial effects of the present invention in detail. It should be understood that the above description is only a specific embodiment of the present invention and is not intended to limit the scope of protection of the present invention. It is particularly pointed out that for those skilled in the art, any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the scope of protection of the present invention.

Claims

1. A method for controlling a soft mist inhalation device, characterized in that: include: Acquiring physical parameters of the soft mist inhalation device, wherein the physical parameters include a maximum single dose of medicament output and a maximum flow rate of the output medicament; Obtaining a single dose of medicine of a user in a current cycle, wherein the single dose of medicine of the user is less than a maximum single dose of medicine output; as well as According to the single dose of medicine of the user, the dose of medicine outputted by the soft mist inhalation device this time is adjusted to be equal to the single dose of medicine.

2. The control method of the soft mist inhalation device according to claim 1, characterized in that: The soft mist inhalation device comprises a medicine bottle, an energy storage module, a liquid pipette, a flow control valve, a suction nozzle, a nozzle outlet, a nozzle, an air inlet and a delivery channel; The medicine bottle is installed inside the device; one end of the pipette is inserted into the medicine bottle, and the other end is used to connect with one end of the flow control valve, the other end of the flow control valve is connected to one end of the delivery channel, the other end of the delivery channel is connected to the inlet of the nozzle, the nozzle outlet is connected to the suction nozzle, and the suction nozzle is connected to the air inlet; The energy storage device is configured so that when a user operates the energy storage device, the medicine in the medicine bottle enters the pipette, which is a medicine loading state.

3. The control method of the soft mist inhalation device according to claim 2, characterized in that: The flow control valve includes a flow sensor; The step of adjusting the amount of medicine outputted by the soft mist inhalation device this time to be equal to the single amount of medicine comprises: Calculating a first time according to the single dose of medicine and the maximum flow rate of the output medicine; In the current cycle, the interval time between opening and closing of the flow control valve is controlled so that the interval time is equal to the first time.

4. The control method of the soft mist inhalation device according to claim 1, characterized in that: The physical parameters also include the initial air inlet area of ​​the nozzle; The control method comprises: Obtaining an initial air inlet area of ​​the soft mist inhalation device, and setting a cycle time and a first ventilation change threshold and a second ventilation change threshold; wherein the first ventilation change threshold is less than the second ventilation change threshold; Acquire the user's respiratory airflow pressure in the current cycle, and calculate the average respiratory resistance according to the respiratory airflow pressure; Calculating a safe ventilation area of ​​the air inlet in the current cycle according to the average respiratory resistance; Calculating, according to the safety ventilation area, the ventilation area adjustment amount of the air inlet in the current cycle; Determine the relationship between the ventilation area adjustment amount and the first ventilation change threshold and the second ventilation change threshold; if the ventilation area adjustment amount is less than the first ventilation change threshold, directly enter the next cycle; if the ventilation area adjustment amount is greater than the first ventilation change threshold and less than the second ventilation change threshold, adjust the air inlet area of ​​the next cycle according to the ventilation area adjustment amount, and enter the next cycle; if the ventilation area adjustment amount is greater than the second ventilation change threshold, control the soft mist inhalation device to stop working and issue an alarm.

5. The control method of the soft mist inhalation device according to claim 4, characterized in that: The obtaining of the user's respiratory airflow pressure in the current cycle and calculating the average respiratory resistance according to the respiratory airflow pressure includes: Acquire the breathing airflow pressure of the user; wherein the breathing airflow pressure includes the airflow pressure when the user inhales and the airflow pressure when the user exhales; Counting the number of breaths of the user in the said cycle; The average respiratory resistance is calculated according to the respiratory airflow pressure and the number of breaths.

6. The control method of the soft mist inhalation device according to claim 5, characterized in that: The step of calculating the safe ventilation area of ​​the air inlet in the current cycle according to the average respiratory resistance includes: The safe ventilation area is calculated according to the following formula: in, represents the safe ventilation area, represents the maximum flow rate of the output medicine, represents the initial air inlet area, represents the average respiratory resistance.

7. The control method of the soft mist inhalation device according to claim 4, characterized in that: The step of calculating the ventilation area adjustment amount of the air inlet in the current cycle according to the safety ventilation area includes: The ventilation area adjustment amount is calculated according to the following formula: in, represents the ventilation area adjustment amount, represents the safe ventilation area, represents the maximum flow rate of the output medicine, represents the initial air inlet area.

8. The control method of the soft mist inhalation device according to claim 4, characterized in that: If the ventilation area adjustment amount is greater than the first ventilation change threshold value but less than the second ventilation change threshold value, adjusting the air inlet area of ​​the next cycle according to the ventilation area adjustment amount, comprising: Calculating the air inlet area of ​​the next cycle according to the ventilation area adjustment amount; Adjusting the air inlet so that the air inlet area of ​​the current cycle becomes the air inlet area of ​​the next cycle; The air inlet area of ​​the next cycle is calculated according to the following formula: in, represents the air inlet area of ​​the next cycle, represents the ventilation area adjustment amount, represents the initial air inlet area.

9. The control method of the soft mist inhalation device according to claim 5, characterized in that: The calculating the average respiratory resistance according to the respiratory airflow pressure and the number of breaths comprises: The average respiratory resistance is calculated according to the following formula, in, represents the average respiratory resistance, Indicates the time it takes for the user to take a breath. represents the cycle time, represents the number of breaths, represents the respiratory airflow pressure.

10. A soft mist inhalation device control device, characterized in that: include: A first acquisition module is used to acquire physical parameters of the soft mist inhalation device, wherein the physical parameters include a maximum dosage of a single dose of medicament output and a maximum flow rate of the output medicament; A second acquisition module is used to acquire a single dose of medicine of a user in a current cycle, wherein the single dose of medicine of the user is less than the output maximum single dose of medicine; as well as The adjustment module is used to adjust the drug dosage output by the soft mist inhalation device this time to be equal to the single drug dosage according to the single drug dosage of the user.

11. A soft mist inhalation device, characterized in that: The invention comprises a processor, a memory, and a computer program stored in the memory and configured to be executed by the processor, wherein when the processor executes the computer program, the control method of the soft mist inhalation device according to any one of claims 1 to 9 is implemented.

12. A computer-readable storage medium, characterized in that: The computer-readable storage medium includes a stored computer program, wherein when the computer program is executed, the device where the computer-readable storage medium is located is controlled to execute the soft mist inhalation device control method according to any one of claims 1 to 9.

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