Tumor electric field treatment system and temperature detection method, signal control method

Abstract

The application provides a tumor electric field treatment system and a temperature detection method and a signal control method. The tumor electric field treatment system comprises at least one pair of electrode sheets, an electric field generator and an adapter. The electrode sheet comprises a plurality of electrode units and a flexible circuit board. The flexible circuit board is embedded with a plurality of ground lines and a plurality of dual-purpose signal lines. Each ground line is connected to the electrode units in the same row. Each dual-purpose signal line is electrically connected to the electrode units in the same column and can transmit alternating current signals and temperature detection signals. The adapter comprises a plurality of groups of multi-circuit lines. At least part of the circuit lines in each group of multi-circuit lines are electrically connected to the corresponding ground lines and dual-purpose signal lines of the electrode sheet. At least one circuit line in each group of circuit lines is in an idle state and is not electrically connected to the dual-purpose signal line or the ground line of the corresponding electrode sheet. The adapter can be adapted to a plurality of electrode sheets with different numbers of ground lines and different numbers of dual-purpose signal lines.

Description

Technical Field

[0001] The present application relates to Tumor Treating Fields (TTF) technology, and in particular to a tumor treating field system, a temperature detection method, and a signal control method. Background Art

[0002] Tumor electric field therapy is a method of treating tumors by using low-intensity, medium- and high-frequency alternating electric fields to prevent the formation of spindle microtubules during mitosis in certain tumor cells, thereby inhibiting the separation of intracellular organelles during cell division and inducing cell apoptosis during mitosis.

[0003] Compared with traditional cancer treatments, TTF has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as geometric shape and high-frequency mitosis, make them susceptible to TTF. TTF disrupts the normal aggregation of tubulin by exerting directional forces on polar particles (such as macromolecules and organelles) in cells. These processes may lead to physical damage to the cell membrane and cell apoptosis. At the end of cell mitosis, the structural morphology of the cleavage furrow will lead to uneven distribution of the electric field around it. At the same time, under the influence of TTF, the electric field intensity at the cleavage furrow is significantly enhanced, and the charged substances in the cell move toward the cleavage furrow, which interferes with or even destroys the formation of the cell structure, and ultimately leads to cell division failure and apoptosis.

[0004] Existing tumor electric field therapy systems use an electric field generator to transmit the alternating current signal for tumor electric field therapy to the electrodes, which then apply an alternating electric field to the patient's tumor site for tumor electric field therapy. When the tumor therapy electric field is applied to the patient's body, heat accumulates at the electrode application site, and the temperature of the electrode application site also rises accordingly. Therefore, it is necessary to monitor the temperature of the electrode application site in real time. When the monitored temperature rises to a certain preset value, it is necessary to promptly adjust the electric field strength applied to the tumor site to avoid excessive temperature at the electrode application site, which may cause burns to the patient's skin.

[0005] A tumor electric field therapy system includes at least one pair of electrode sheets, each of which contains multiple electrode units. Even when the same alternating current signal is applied to each electrode unit, the heat generated by each electrode unit will vary depending on its location. This means that the temperature of each electrode unit across the entire electrode sheet will not be completely consistent. This can result in some electrode units exceeding a preset temperature while other electrode units remain within normal limits. To prevent excessively high patient surface temperatures during prolonged tumor electric field therapy and to ensure that an alternating electric field can be applied to the patient's tumor site for a long period of time, it is necessary to individually control overheated electrode units. However, with existing electrode sheets, individually controlling the electrode units requires providing a conductive trace for each electrode unit within the electrode sheet's substrate. This increases the number of conductive traces within the electrode sheet's substrate, making it difficult to bend the electrode sheet. Furthermore, the cables electrically connected to the electrode sheet will be thicker, increasing the overall weight of the electrode sheet and hindering its application.

[0006] Therefore, it is necessary to provide an electrode sheet, a tumor electric field therapy system, a temperature detection method, and a signal application method that use fewer conductive traces to perform partitioned control on multiple electrode units. Summary of the Invention

[0007] The first object of the present application is to provide a tumor electric field therapy system to solve or eliminate the problems in the related art.

[0008] The second object of the present application is to provide a method for detecting the temperature of an electrode.

[0009] The third object of the present application is to provide a signal control method for tumor electric field therapy.

[0010] To achieve the above-mentioned objectives, the present application provides the following technical solutions: a tumor electric field therapy system, comprising: at least one pair of electrode sheets, the electrode sheets comprising a plurality of electrode units and a flexible circuit board, the plurality of electrode units being divided into a plurality of row groups and a plurality of column groups on a circuit; the flexible circuit board being configured for the plurality of electrode units to be arranged thereon at intervals, the flexible circuit board having multiple conductive traces embedded therein, the multiple conductive traces comprising: multiple grounding lines and multiple dual-purpose signal lines, the multiple grounding lines being connected to the plurality of row groups in a one-to-one correspondence, each grounding line being configured to short-circuit each electrode unit in a corresponding row group to ground, the multiple dual-purpose signal lines being connected to the plurality of column groups in a one-to-one correspondence, each dual-purpose signal line being configured to transmit both an alternating current signal to each electrode unit in a corresponding column group and a direct current signal to each electrode unit in a corresponding column group, or to transmit a direct current signal to each electrode unit in a corresponding column group. an electric field generator configured to provide an alternating current signal to a plurality of electrode units of the electrode sheet via the dual-purpose signal line of the electrode sheet; and an adapter connected between the electrode sheet and the electric field generator, having a plurality of groups of multi-channel circuit lines and configured to transmit the alternating current signal generated by the electric field generator to the multi-channel dual-purpose signal line corresponding to the electrode sheet through the corresponding circuit lines in the corresponding groups of circuit lines, and further configured to receive the temperature detection signal output by the multi-channel dual-purpose signal line corresponding to the electrode sheet through the corresponding circuit lines in the corresponding groups of circuit lines, part of the circuit lines in each group of multi-channel circuit lines are electrically connected one-to-one with the multi-channel dual-purpose signal lines and the multi-channel ground lines corresponding to the electrode sheet, and at least one circuit line in each group of multi-channel circuit lines is in an idle state and is not electrically connected with the dual-purpose signal line corresponding to the electrode sheet or the ground line corresponding to the electrode sheet.

[0011] The tumor electric field therapy system of the present application features multiple dual-purpose signal lines on the flexible circuit board of the electrode sheet. Each dual-purpose signal line connects multiple electrode units in the same column of the circuit, transmitting both AC and DC signals to collect temperature detection signals from each electrode unit. This eliminates the need for separate conductive traces solely for AC signal transmission, reducing the number of wires required to electrically connect the electrode sheet to the adapter. Furthermore, the adapter includes idle circuit lines corresponding to the multiple circuit lines of the electrode sheet, allowing it to accommodate a variety of electrode sheets with varying numbers of ground lines and dual-purpose signal lines.

[0012] Furthermore, the adapter also includes multiple groups of bidirectional switching switches electrically connected one-to-one with multiple groups of circuit lines, each group of bidirectional switching switches is electrically connected one-to-one with the corresponding circuit lines in the corresponding group and includes multiple bidirectional switching switches, at least some of the multiple bidirectional switching switches in each group are electrically connected one-to-one with the multiple dual-purpose signal lines of the corresponding electrode pieces to control the multiple dual-purpose signal lines of the corresponding electrode pieces to transmit alternating current signals or temperature detection signals.

[0013] Furthermore, the adapter includes multiple groups of grounding switches electrically connected one-to-one with multiple groups of circuit lines, each group of grounding switches is electrically connected one-to-one with the corresponding circuit lines in the corresponding group and includes multiple grounding switches, at least some of the multiple grounding switches in each group are electrically connected one-to-one with the multiple grounding lines of the corresponding electrode sheets and control the conduction or disconnection of the multiple grounding lines of the electrode sheets electrically connected to them.

[0014] Furthermore, at least one bidirectional switch or at least one grounding switch in each group of bidirectional switches and each group of grounding switches of the adapter is in an idle state, and the bidirectional switch in the idle state is not electrically connected to the dual-purpose signal line corresponding to the electrode sheet, and the grounding switch in the idle state is not electrically connected to the grounding line corresponding to the electrode sheet.

[0015] Furthermore, each group of the multiple circuit lines of the adapter also includes: an AC signal line, which is configured to provide alternating current signals to each of the electrode units in the corresponding column group of the electrode sheet through the multiple dual-purpose signal lines of the corresponding electrode sheet.

[0016] Furthermore, the adapter also includes: multiple groups of analog-to-digital converters, each group of analog-to-digital converters is electrically connected to the corresponding electrode sheet's multiplexed signal line through the corresponding group's multiplexed circuit line, and is configured to receive the temperature detection signal transmitted by the corresponding electrode sheet's multiplexed signal line through the corresponding group's corresponding circuit line and convert the temperature detection signal from an analog signal to a digital signal, wherein each group of analog-to-digital converters includes multiple detection channels, and each of the bidirectional switches also has an acquisition end electrically connected to a corresponding detection channel in the corresponding analog-to-digital converter and an input end electrically connected to the AC signal line.

[0017] Furthermore, the number of the grounding switches in each group is 4, and / or the number of the bidirectional switches in each group is 5.

[0018] Furthermore, each of the electrode units includes a dielectric element for transmitting an AC signal and a temperature sensor having a signal end and a ground end. The temperature sensor is used to detect the temperature of the corresponding electrode unit. The dielectric element of each electrode unit is short-circuited with the signal end of the corresponding temperature sensor.

[0019] Furthermore, each of the electrode units further includes a diode connected in series with the temperature sensor, and the temperature sensor is grounded via the diode connected in series with the temperature sensor.

[0020] Furthermore, the plurality of electrode units are arranged into multiple rows and columns in a spatial structure, and the flexible circuit board is provided with a connection portion connecting two adjacent electrode units, wherein the electrode sheet is provided with a gap formed between two adjacent electrode units along the column direction and along the row direction.

[0021] Furthermore, when performing temperature detection on each electrode unit of the electrode sheet, the multiple bidirectional switches electrically connected to the electrode sheet are placed at their respective collection ends, and only one of the multiple grounding switches electrically connected to the electrode sheet is turned on at the same time, and the rest are disconnected.

[0022] Furthermore, when an alternating current signal is applied to each electrode unit of the electrode sheet, all or part of the multiple bidirectional switches electrically connected to the electrode sheet are placed at the input end, and all of the multiple grounding switches electrically connected to the electrode sheet are disconnected.

[0023] Furthermore, the adapter also includes: a first controller, which is respectively connected to the multiple groups of grounding switches and the multiple groups of bidirectional switching switches, and is configured to: control the opening and closing states of the multiple grounding switches in each group of grounding switches in sequence and cycle, and then sequentially and individually turn on each grounding line in the multiple grounding lines of the corresponding electrode sheet; and control the switching states of the multiple bidirectional switching switches in each group of bidirectional switching switches, so that each bidirectional switching switch is placed at the acquisition end to output a temperature detection signal or each bidirectional switching switch is placed at the input end to transmit an AC signal.

[0024] Furthermore, the adapter further includes: a first communication unit configured to obtain digital signals output by the multiple groups of analog-to-digital converters and send the digital signals to the electric field generator.

[0025] Furthermore, the electric field generator is further configured to control or adjust the alternating current signal provided to the corresponding electrode unit among the plurality of electrode units of the corresponding electrode sheet according to the received digital signal.

[0026] Furthermore, the first communication unit is controlled by the first controller and serially transmits the digital signal converted by the analog-to-digital converter.

[0027] To achieve the above-mentioned purpose, the present application also provides the following technical solution: a temperature detection method, applied to the aforementioned tumor electric field therapy system, the method comprising the following steps: turning on all the respective collection ends of the multiplexed signal lines corresponding one-to-one to the multiple column groups of the corresponding electrode sheet; and turning on each of the multiple grounding lines corresponding one-to-one to the multiple row groups of the electrode sheet in sequence and in a time-sharing manner to collect the temperature detection signals of each electrode unit in each row group of the electrode sheet by row through the multiplexed signal lines.

[0028] To achieve the above-mentioned purpose, the present application also provides the following technical solution: a method for detecting temperature anomaly, wherein the temperature anomaly is judged based on the temperature detection signal of each electrode unit of the electrode sheet obtained by the above-mentioned method.

[0029] Furthermore, the temperature abnormality judgment of the tumor electric field therapy system includes the following steps: comparing the obtained temperature of each electrode unit with a preset temperature threshold; and judging whether the temperature of the electrode sheet is abnormal based on the comparison result.

[0030] Furthermore, the comparison result includes not exceeding the preset temperature threshold and exceeding the preset temperature threshold. Whether the temperature of the electrode sheet is abnormal is judged as follows: when the temperature of one of the electrode units exceeds the preset temperature threshold, it is determined that the electrode sheet has a temperature abnormality; or when the temperatures of all electrode units do not exceed the preset temperature threshold, it is determined that the electrode sheet does not have a temperature abnormality.

[0031] Furthermore, the preset temperature threshold is 40.5°C-41.5°C.

[0032] Furthermore, the preset temperature threshold is 41°C-41.5°C.

[0033] Furthermore, the preset temperature threshold is 41°C.

[0034] To achieve the above objectives, the present application also provides the following technical solution: a method for controlling the application of alternating current signals for tumor electric field therapy, which is applied to the aforementioned tumor electric field therapy system.

[0035] Furthermore, the alternating current signal applied to each electrode unit of the electrode sheet is controlled or adjusted according to the temperature detection signal of each electrode unit of the electrode sheet obtained by the aforementioned method.

[0036] Furthermore, the controlling or adjusting the AC signal applied to each electrode unit of the electrode sheet includes: comparing the obtained temperature of each electrode unit with a preset temperature threshold; and controlling or adjusting the AC signal applied according to the comparison result.

[0037] Furthermore, the AC signal applied to each electrode unit of the electrode sheet is controlled or adjusted according to the comparison result in the following manner: when the temperature detection signals of each electrode unit of the electrode sheet obtained do not exceed the preset temperature threshold, the AC signal continues to be applied to each electrode unit of the electrode sheet; or when there is a temperature detection signal among the temperature detection signals of each electrode unit of the electrode sheet obtained that exceeds the preset temperature threshold, the application of the AC signal to the electrode unit of the electrode sheet is stopped.

[0038] Furthermore, stopping applying AC signals to the electrode units of the electrode sheet includes stopping applying AC signals to all electrode units of the electrode sheet, stopping applying AC signals to electrode units in the electrode sheet whose temperature detection signals exceed a preset temperature threshold, and stopping applying AC signals to all electrode units in the column where the electrode units in the electrode sheet whose temperature detection signals exceed a preset temperature threshold are located.

[0039] Furthermore, when the application of the AC signal to the electrode unit in the electrode sheet whose temperature detection signal exceeds the preset temperature threshold is stopped, the AC signal continues to be applied to the electrode unit in the electrode sheet whose temperature detection signal does not exceed the preset temperature threshold.

[0040] Furthermore, when the application of the alternating current signal to all electrode units in the column where the electrode unit whose temperature detection signal in the electrode sheet exceeds the preset temperature threshold is located is stopped, the alternating current signal continues to be applied to all electrode units in the electrode sheet where the temperature detection signal does not exceed the preset temperature threshold and is in a different column from the electrode unit whose temperature detection signal exceeds the preset temperature threshold.

[0041] Furthermore, the comparison result includes not exceeding a preset temperature threshold and exceeding a preset temperature threshold, and not exceeding a preset temperature threshold includes being far below a preset temperature threshold and being close to a preset temperature threshold.

[0042] Further, when the temperature detection signals of the electrode units of the electrode sheet do not exceed the preset temperature threshold, the AC signal is continuously applied to the electrode units of the electrode sheet in the following manner: when the temperature detection signal is far below the preset temperature threshold, the AC signal is continuously applied to the electrode units of the electrode sheet in a manner of increasing the voltage or current amplitude of the AC signal currently applied to the electrode units of the electrode sheet or in a manner of keeping the voltage or current amplitude of the AC signal currently applied to the electrode units of the electrode sheet unchanged; or when the temperature detection signal is close to the preset temperature threshold, the AC signal is continuously applied to the electrode units of the electrode sheet in a manner of keeping the voltage or current amplitude of the AC signal currently applied to the electrode units of the electrode sheet unchanged or in a manner of reducing the voltage or current amplitude of the AC signal currently applied to the electrode units of the electrode sheet.

[0043] Further, the preset temperature threshold is 40.5-41.5℃.

[0044] Further, the preset temperature threshold is 41-41.5℃.

[0045] Further, the preset temperature threshold is 41℃.

[0046] To achieve the above object, the present application further provides the following technical solution: a signal control method for tumor electric field therapy, applied to the tumor electric field therapy system.

[0047] Further, the tumor electric field therapy signal is obtained by combining the on and off of the multiple two-purpose signal lines respectively corresponding to each column group of the electrode sheet and electrically connected to the electrode units of each column group and the multiple ground lines respectively corresponding to each row group of the electrode sheet and electrically connected to the electrode units of each row group, and by the multiple two-purpose signal lines electrically connected to each electrode unit of the electrode sheet to realize the cyclic switching of each electrode unit of the electrode sheet between applying an AC signal and collecting or transmitting a temperature detection signal.

[0048] Further, the process of applying an AC signal to each electrode unit of the electrode sheet includes the following steps: disconnecting the multiple ground lines respectively corresponding to the electrode units of each row group of the electrode sheet, and simultaneously turning on the input ends of the multiple two-purpose signal lines respectively corresponding to the electrode units of each column group of the electrode sheet to make the multiple two-purpose signal lines electrically connected to the electrode sheet transmit an AC signal to each electrode unit.

[0049] Furthermore, the process of transmitting temperature detection signals to each electrode unit of the electrode sheet includes the following steps: turning on the respective acquisition ends of the multiple dual-purpose signal lines electrically connected one by one to the electrode units of each column group of the electrode sheet so that the multiple dual-purpose signal lines electrically connected to the electrode sheet transmit DC signals to each electrode unit; and sequentially turning on one ground line of the multiple ground lines electrically connected one by one to the electrode units of each row group of the electrode sheet so as to complete the transmission of the temperature detection signals of each electrode unit in each row group of the electrode sheet row by row through the multiple dual-purpose signal lines electrically connected to the electrode sheet.

[0050] Furthermore, the method also includes the steps of: determining a combined control method for turning on or off the multiple ground lines corresponding to each row group of the electrode sheet and the multiple dual-purpose signal lines corresponding to each column group of the electrode sheet based on the temperature detection signals obtained from each electrode unit; and controlling the working state of each electrode unit of the electrode sheet based on the determined combined control method for turning on or off the multiple ground lines and the multiple dual-purpose signal lines.

[0051] Furthermore, the working state of each electrode unit of the electrode sheet includes one of stopping applying the alternating current signal and continuing to collect the temperature detection signal and stopping collecting the temperature detection signal and continuing to apply the alternating current signal.

[0052] Furthermore, continuing to apply the AC signal includes continuing to apply the AC signal in a manner of increasing the voltage or current amplitude of the currently applied AC signal, continuing to apply the AC signal in a manner of maintaining the voltage or current amplitude of the currently applied AC signal unchanged, or continuing to apply the AC signal in a manner of reducing the voltage or current amplitude of the currently applied AC signal.

[0053] The above description is only an overview of the technical solution of the present application. In order to more clearly understand the technical means of the present application, it can be implemented in accordance with the contents of the specification. In order to make the above and other purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are listed below. BRIEF DESCRIPTION OF THE DRAWINGS

[0054] Figure 1 A schematic diagram of a framework of a tumor electric field treatment system according to an embodiment of the present application, showing a schematic diagram of the structure of the electrode sheet according to the first embodiment;

[0055] Figure 2 For use in this application Figure 1 A schematic structural diagram of an alternative embodiment of the electrode sheet of the first embodiment of the tumor electric field treating system is shown;

[0056] Figure 3For this application Figure 1 The circuit connection diagram of the tumor electric field system is shown in FIG. Figure 1 The electrode sheet of the first embodiment shown or Figure 2 The electrode sheet of the modified embodiment shown in FIG. Figure 1 A circuit connection diagram of the adapter of the first embodiment shown in FIG;

[0057] Figure 4 For this application Figure 3 A schematic block diagram of the internal structure of the adapter shown;

[0058] Figure 5 For this application Figure 1 A schematic block diagram of the internal structure of an electric field generator of a tumor treating field system is shown;

[0059] Figure 6 and Figure 3 Similarly, the circuit connection diagram of the tumor electric field treatment system of the second embodiment of the present application is shown, which shows the electrode sheet and the second embodiment of the tumor electric field treatment system of the present application. Figure 3 The circuit connection diagram of the adapter shown;

[0060] Figure 7 and Figure 3 Similarly, the circuit connection diagram of the tumor electric field treatment system of the third embodiment of the present application is shown, which shows the electrode sheet and the third embodiment of the tumor electric field treatment system of the present application. Figure 3 The circuit connection diagram of the adapter shown;

[0061] Figure 8 and Figure 3 Similarly, the circuit connection diagram of the tumor electric field treatment system of the fourth embodiment of the present application is shown, which shows the electrode sheet and the fourth embodiment of the tumor electric field treatment system of the present application. Figure 3 The circuit connection diagram of the adapter shown;

[0062] Figure 9 and Figure 1 Similarly, FIG. 5 is a schematic diagram of a framework of a tumor electric field treating system according to a fifth embodiment of the present application, which shows a schematic diagram of the structure of the electrode sheet according to the fifth embodiment;

[0063] Figure 10 and Figure 3 Similar to Figure 9 A circuit connection diagram of the tumor electric field treatment system is shown in FIG. Figure 9 The electrode sheet of the fifth embodiment shown is Figure 3 The circuit connection diagram of the adapter shown;

[0064] Figure 11 and Figure 10 Similarly, the circuit connection diagram of the tumor electric field treatment system of the sixth embodiment of the present application is shown.

[0065] Figure 9 The electrode sheet of the fifth embodiment shown is Figure 3 Another circuit connection diagram of the adapter shown;

[0066] Figure 12 and Figure 11 Similarly, the circuit connection diagram of the tumor electric field therapy system of the seventh embodiment of the present application is shown. Figure 9 The electrode sheet of the fifth embodiment shown is Figure 3 Another circuit connection diagram of the adapter shown;

[0067] Figure 13 and Figure 11 Similarly, the circuit connection diagram of the tumor electric field treatment system of the eighth embodiment of the present application is shown.

[0068] Figure 9 The electrode sheet of the fifth embodiment shown is Figure 3 Another circuit connection diagram of the adapter shown;

[0069] Figure 14 and Figure 1 Similarly, FIG. 1 is a schematic diagram of a framework of a tumor treating field system according to a ninth embodiment of the present application, which shows a schematic diagram of the structure of the electrode sheet according to the ninth embodiment;

[0070] Figure 15 for Figure 14 The circuit connection diagram of the tumor electric field treatment system is shown in FIG. Figure 14 The electrode sheet of the ninth embodiment shown is Figure 3 The circuit connection diagram of the adapter shown;

[0071] Figure 16 and Figure 15 Similarly, the circuit connection diagram of the tumor electric field treatment system of the tenth embodiment of the present application is shown.

[0072] Figure 14 The electrode sheet of the ninth embodiment shown is Figure 3 Another circuit connection diagram of the adapter shown;

[0073] Figure 17 This is a flow chart of a temperature detection method for a tumor electric field therapy system according to an embodiment of the present application;

[0074] Figure 18 This is a flow chart of a method for controlling application of an alternating current signal for tumor electric field therapy according to an embodiment of the present application;

[0075] Figure 19 Flowchart of a signal control method for tumor electric field therapy according to an embodiment of the present application;

[0076] Figure 20 Flowchart of an electrode sheet temperature detection method according to another embodiment of the present application;

[0077] Figure 21 Flowchart of an alternating current signal application method for tumor electric field therapy according to another embodiment of the present application;

[0078] Figure 22 Flowchart of an alternating current signal application method based on a temperature detection signal according to an embodiment of the present application;

[0079] Figure 23 Flowchart of an alternating current signal application method based on a temperature detection signal according to another embodiment of the present application.

[0080] BRIEF DESCRIPTION OF DRAWINGS

[0081] Tumor electric field therapy system 100, electrode sheet 10, 10A, 10B, 10C, 10D, 10E, 10F, 10G, 10H, 10J, flexible circuit board 11, 11A, 11B, 11C, 11D, 11E, 11F, 11G, 11H, 11J, connection portion 111, wiring portion 112, bridging portion 113, electrode unit 12, first cable 13, temperature sensor 14, ground terminal 14-1, signal terminal 14-2, dielectric element 15, diode 16, ground wire 18, first ground wire 18-1, second ground wire 18-2, third ground wire 18-3, fourth ground wire 18-4, dual-purpose signal wire 19, first dual-purpose signal wire 19-1, second dual-purpose signal wire 19-2, third dual-purpose signal wire 19-3, fourth dual-purpose signal wire 19-4, fifth dual-purpose signal wire 19-5, adapter 20, second cable 21, first controller 22, analog-to-digital converter 23, voltage dividing resistor 24, ground switch 25, first ground switch 25-1, second ground switch 25-2, third ground switch 25-3, fourth ground switch 25-4, bidirectional switch 26, first bidirectional switch 26-1, second bidirectional switch 26-2, third bidirectional switch 26-3, fourth bidirectional switch 26-4, fifth bidirectional switch 26-5, first communication unit 27, AC signal wire 28, first power supply module 29, electric field generator 30, second power supply module 31, second controller 32, second communication unit 33, AC signal generator 34, AC signal switch 35, first connector 40, first plug 41, first socket 42, second connector 50, second plug 51, second socket 52. DETAILED DESCRIPTION

[0082] The following embodiments of the technical solution of the present application will be described in detail with reference to the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present application and are therefore only examples and are not intended to limit the scope of protection of the present application.

[0083] Figure 1 FIG. 1 is a schematic diagram of a tumor electric field treatment system 100 according to an embodiment of the present application. Figure 1 As shown, the tumor electric field therapy system 100 includes: at least one pair of electrode sheets 10, an adapter 20 electrically connected to the electrode sheets 10, and an electric field generator 30 electrically connected to the adapter 20. The electric field generator 30 generates an alternating current signal for tumor treatment and applies the alternating current signal to the electrode sheets 10 through the adapter 20, so as to generate an alternating current signal in the paired electrode sheets 10. The adapter 20 is electrically connected between the electrode sheets 10 and the electric field generator 30, and is used to transmit the alternating current signal generated by the electric field generator 30 to the electrode sheets 10. In other words, the electric field generator 30 is capable of generating an alternating current signal, and the alternating current signal generated by the electric field generator 30 is transmitted to each electrode sheet 10 through the adapter 20, so that a therapeutic electric field for treating tumors is generated between the same pair of electrode sheets 10.

[0084] like Figure 1 As shown, in this embodiment, the number of electrode sheets 10 is 4. From the perspective of spatial structural arrangement, each electrode sheet 10 includes a plurality of electrode units 12 that are both axially symmetrically arranged and centrally symmetrically arranged and of the same number, a plurality of connecting portions 111 located between two adjacent electrode units 12, a bridging portion 113 erected between two adjacent connecting portions 111, a wiring portion 112 connected to the bridging portion 113, and a first cable 13 connected to the wiring portion 112. The bridging portion 113 and the wiring portion 112 are arranged vertically to form a "T" shape. The bridging portion 113 is erected between two adjacent connecting portions 111. Each electrode unit 12 of the electrode sheet 10 is electrically connected to the adapter 20 via the first cable 13.

[0085] Each electrode unit 12 has a temperature sensor 14 and a dielectric element 15. The temperature sensor 14 is used to detect the temperature of the part of the patient's body surface to which the electrode unit 12 is applied. It can be a thermistor element or a temperature sensor other than a thermistor, and can be set at any position on the electrode unit 12. The dielectric element 15 is used to apply an AC signal to the patient's tumor site. The dielectric element 15 can be a dielectric ceramic sheet or a polymer dielectric layer composed of a polymer material. In this embodiment, each dielectric element 15 has a through-hole (unnumbered) provided in the middle for accommodating a corresponding temperature sensor 14. Each electrode unit 12 can also include a diode 16 connected in series with the temperature sensor 14, which can prevent the reverse flow of current to prevent the detection signal from other electrode units 12 from affecting the temperature sensor 14. The ground terminal 14-1 of the temperature sensor 14 is connected in series with the anode of the diode 16 and is grounded through the cathode of the diode 16.

[0086] In a first mode, the electrode unit 12 applies an AC signal via the dielectric element 15. In a second mode, the temperature sensor 14 detects or collects the temperature of the patient's body surface to which the corresponding electrode unit 12 is applied. In a third mode, the application of the AC signal and temperature detection and collection cease. The first, second, and third modes do not overlap in time periods. That is, the time periods during which the dielectric element 15 of the electrode unit 12 applies the AC signal are staggered and do not overlap with the time periods during which the temperature sensor 14 detects temperature. The electrode unit 12 can cyclically switch between applying the AC signal via its dielectric element 15 and detecting temperature via its temperature sensor 14, that is, the electrode unit 12 can cyclically switch between the first and second modes. The electrode unit 12 can also cyclically switch between the first, second, and third modes, that is, the electrode unit 12 cyclically switches between applying the AC signal via the dielectric element 15, collecting or detecting temperature via the temperature sensor 14, and then cessation of applying the AC signal and collecting temperature.

[0087] Each electrode sheet 10 includes an electrode array (unnumbered) consisting of 20 electrode units 12. The electrode array (unnumbered) also has a flexible circuit board 11 including a connecting portion 111, a wiring portion 112, and a bridging portion 113. The 20 electrode units 12 are distributed in an electrode array (unnumbered) arranged in four rows and six columns. Specifically, the first and last rows each have four electrode units 12, and the middle two rows each have six electrode units 12. The four electrode units 12 in the first row are respectively located in each of the second to fifth columns, the six electrode units 12 in each of the middle two rows are respectively located in each of the first to sixth columns, and the four electrode units 12 in the last row are also respectively located in each of the second to fifth columns.

[0088] The connecting portion 111 is located only between two adjacent electrode units 12 arranged in the column direction in each of the third and fourth columns, and between two adjacent electrode units 12 in the row direction, excluding the two electrode units 12 in the third and fourth columns. That is, the two adjacent electrode units 12 in the third and fourth columns are connected only in the column direction via the connecting portion 111, and are disconnected in the row direction, not connected by the connecting portion 111. The electrode units 12 in each of the first, second, fifth, and sixth columns are connected only to the electrode units 12 adjacent in the row direction via the horizontally arranged connecting portion 111, and are disconnected in the column direction from the electrode units 12 adjacent to them. In other words, the two adjacent electrode units 12 in the first, second, fifth, and sixth columns are disconnected.

[0089] The electrode units 12 in the third column and the longitudinally disposed connecting portions 111 between the electrode units 12 in that column, as well as the electrode units 12 in the fourth column and the longitudinally disposed connecting portions 111 between the electrode units 12 in that column, constitute the backbone 114 of the electrode array (unnumbered). The connecting portions 111 located on opposite sides of the electrode units 12 in the third and fourth columns, connected to the electrode units 12 in the third and fourth columns via the transversely disposed connecting portions 111, and the electrode units 12 connected to the transversely disposed connecting portions 111, constitute the branches 115 of the electrode array (unnumbered). In other words, in this embodiment, the electrode array (unnumbered) includes two backbones 114 and a plurality of branches 115 extending laterally from the two backbones 114. Each branch 115 has a free end distal from the backbone 114. The free ends of adjacent branches 115 are disconnected, and the position and distance between adjacent branches 115 can be freely adjusted according to actual usage scenarios. Specifically, one trunk 114 is composed of the electrode units 12 in the third column and the longitudinally arranged connecting portions 111 between adjacent electrode units 12 in the column. Another trunk 114 is composed of the electrode units 12 in the fourth column and the longitudinally arranged connecting portions 111 between adjacent electrode units 12 in the column. The remaining electrode units 12 connected to the trunk 114 via the transversely arranged connecting portions 111 and the transversely arranged connecting portions 111 are all branches 115.

[0090] Specifically, the branches 115 are: a connecting portion 111 extending laterally to the left from the electrode unit 12 in the first row of the third column and located in the first row, and an electrode unit 12 connected to the connecting portion 111 and located in the second column of the first row; two connecting portions 111 extending laterally to the left from the electrode unit 12 in the second row of the third column and located in the second row, and two electrode units 12 located in the first column of the second row and the second column of the second row; two connecting portions 111 extending laterally to the left from the electrode unit 12 in the third row of the third column and located in the third row, and two electrode units 12 located in the first column of the third row and the second column of the third row; a connecting portion 111 extending laterally to the left from the electrode unit 12 in the fourth row and located in the fourth row, and The electrode unit 12 in the second column of the fourth row; a connecting portion 111 extending laterally to the right from the electrode unit 12 in the first row of the fourth column and located in the first row, and the electrode unit 12 located in the fifth column of the first row; two connecting portions 111 extending laterally to the right from the electrode unit 12 in the second row of the fourth column and located in the second row, and two electrode units 12 located in the fifth column of the second row and the sixth column of the second row; two connecting portions 111 extending laterally to the right from the electrode unit 12 in the third row of the fourth column and located in the third row, and two electrode units 12 located in the fifth column of the third row and the sixth column of the third row; a connecting portion 111 extending laterally to the right from the electrode unit 12 in the fourth row of the fourth column and located in the fourth row, and the electrode unit 12 located in the fifth column of the fourth row.

[0091] The electrode array (unnumbered) is divided into a symmetrical left portion comprising three columns on the left and a right portion comprising three columns on the right, and the left portion and the right portion are connected only by a bridge portion 113. The left portion is composed of a trunk 114 located in the third column and a plurality of branches 115 extending laterally to the left from the trunk 114, and the right portion is composed of a trunk 114 located in the fourth column and a plurality of branches 115 extending laterally to the right from the trunk 114. The two trunks 114 are connected by a bridge portion 113 provided therebetween. Specifically, the two trunks 114 are electrically connected by a bridge portion 113 provided between a connection portion 111 connecting the electrode unit 12 in the second row of the third column and the electrode unit 12 in the third row of the third column and a connection portion 111 connecting the electrode unit 12 in the second row of the fourth column and the electrode unit 12 in the third row of the fourth column. The connecting portion 111 connecting the electrode unit 12 in the second row of the third column with the electrode unit 12 in the third row of the third column, the connecting portion 111 connecting the electrode unit 12 in the second row of the fourth column with the electrode unit 12 in the third row of the fourth column, and the bridging portion 113 are generally arranged in an "H" shape. In other embodiments, the bridging portion 113 may also be provided between an electrode unit 12 in the third column and an electrode unit 12 in the fourth column. Alternatively, the bridging portion 113 may be provided between two electrode units 12 in the third and fourth columns that are adjacent in the row direction.

[0092] Each electrode unit 12 can be divided into an electrode unit 12 located at the periphery and an electrode unit 12 located at the center according to its position in the electrode array (unnumbered). The electrode units 12 located at the periphery include four electrode units 12 located in the first row, two electrode units 12 located at opposite ends of the second row, two electrode units 12 located at opposite ends of the third row, and four electrode units 12 located in the fourth row. The electrode units 12 located at the center include four electrode units 12 located in the middle of the second row and four electrode units 12 located in the middle of the third row. Some adjacent two electrode units 12 in the plurality of electrode units 12 located at the periphery are connected by a laterally arranged connecting portion 111, and some adjacent two electrode units 12 are arranged in a disconnected state. Among the plurality of electrode units 12 located at the periphery, the adjacent two electrode units 12 connected by the connecting portion 111 are two electrode units 12 that are adjacent in some rows. Specifically, among the plurality of electrode units 12 located at the periphery, two adjacent electrode units 12 in the column direction and two adjacent electrode units 12 in the diagonal direction are all disconnected; some adjacent electrode units 12 in the row direction are also disconnected; and only some adjacent electrode units 12 in the row direction are connected by a laterally extending connection portion 111. Among the plurality of electrode units 12 located at the center, only two adjacent electrode units 12 in the column direction on the trunk 114 are connected by a longitudinally arranged connection portion 111, and only two adjacent electrode units 12 in the row direction on the branches 115 are connected by a laterally arranged connection portion 111.

[0093] The electrode array (unnumbered) also includes spaces (unnumbered) formed between the spaced electrode units 12. These spaces allow moisture from the patient's body to escape, heat exchange between the patient's skin and the surrounding environment, and allow the patient's skin to breathe freely. They also allow for flexible adjustment of the position and spacing between the branches 115 and prevent wrinkles when the electrode sheet 10 is applied. The spaces (unnumbered) include a first space D1 between the two trunks 114 and a second space D2 between the branches 115. The first space D1 is located between the third and fourth columns of electrode units 12, while the second space D2 is located between adjacent rows of electrode units 12. That is, going up along the row, the electrode unit 12 located in the third column is disconnected from the adjacent electrode unit 12 located in the fourth column, and no connecting portion 111 is provided, but the aforementioned first interval D1 is formed; and going up along the column, only the two adjacent electrode units 12 in the third and fourth columns are connected by the connecting portion 111, and the two adjacent electrode units 12 in the column direction in each of the other four columns are not connected by the connecting portion 111 but form the aforementioned second interval D2. The setting of the first and second intervals D1 and D2 can also increase the degree of freedom of some electrode units 12, and can also avoid wrinkles when attaching the electrode sheet 10.

[0094] In some other embodiments, the tumor electric field therapy system 100 may also have more or fewer electrode sheets 10. In some other embodiments, each pair of electrode sheets 10 has the same number of electrode units 12, and different pairs of electrode sheets 10 may have different numbers of electrode units 12. In some other embodiments, the 20 electrode units 12 may also be arranged in other ways. Of course, in some other embodiments, the electrode sheet 10 may also have other numbers of electrode units 12. In short, the implementation of the present application is not limited by the number and arrangement of the electrode units 12 of the electrode sheet 10.

[0095] Figure 2 The electrode sheet 10' shown is Figure 1 A variation of the electrode sheet 10 shown in FIG. 1 is a variation of the electrode sheet 10, wherein the spatial structure of the electrode sheet 10 ′ is the same as that of the electrode sheet 10 and also includes a plurality of electrode units 12 ′ arranged at intervals, a plurality of connecting portions 111 ′ located between two adjacent electrode units 12 ′, a wiring portion 112 ′ connected to the bridging portion 113 ′, a first cable 13 ′ connected to the wiring portion 112 ′, a first interval D1 formed between the third column of electrode units 12 ′ and the fourth column of electrode units 12 ′, and a second interval D2 ′ formed between adjacent rows of electrode units 12 ′; The only difference is that: the two electrode units 12' located in the fourth column and adjacent to each other in the column direction are both disconnected and not connected by the longitudinally arranged connecting portion 111', but the two electrode units 12' located in the fifth column and adjacent to each other in the column direction are connected by the longitudinally arranged connecting portion 111', and each electrode unit 12' located in the fourth column is connected to the electrode unit 12' located in the fifth column and adjacent to each other in the row direction through the transversely arranged connecting portion 111'; and the bridging portion 113' is connected between the two electrode units 12' located in the third row and the third column and the electrode unit 12' located in the third row and the fourth column.

[0096] Figure 3 for Figure 1 The diagram shows a circuit connection diagram of the first embodiment of the electrode sheet 10 or its variant embodiment of the electrode sheet 10 and the adapter 20 for the tumor electric field treatment system 100. It is worth noting that: Figure 3 The arrangement of the electrode units 12 is shown to more clearly illustrate the electrical connection between an electrode sheet 10 and the adapter 20. Figure 3 The arrangement of the electrode units 12 shown does not represent the arrangement of the electrode units 12 in the spatial structure. The following describes the circuit connection by taking the electrode sheet 10 in the first embodiment as an example. Figure 1 as well as Figure 3The flexible circuit board 11 is embedded with multiple conductive traces, including multiple grounding traces 18 and multiple dual-purpose signal traces 19. The first cable 13 comprises multiple conductors (not shown) that are electrically connected to the multiple grounding traces 18 and multiple dual-purpose signal traces 19 on the flexible circuit board 11 in a one-to-one correspondence. The total number of grounding traces 18 and dual-purpose signal traces 19 embedded in the flexible circuit board 11 does not exceed 10. Therefore, the number of conductors in the first cable 13 does not exceed 10.

[0097] In this embodiment, each electrode sheet 10 is provided with 20 electrode units 12. The 20 electrode units 12 are arranged in the order of 1 to 20 for circuit connection, divided into four row groups and five column groups. That is, the 20 electrode units 12 are arranged in four rows and five columns for circuit connection. The temperature sensor 14 enclosed by each electrode unit 12 includes a ground terminal 14-1 and a signal terminal 14-2. The dielectric element 15 and temperature sensor 14 of each electrode unit 12 are soldered to the flexible circuit board 11, and each dielectric element 15 is short-circuited with the signal terminal 14-2 of the corresponding temperature sensor 14. Since the electrode units 12 are arranged in four rows and five columns for circuit connection, and each electrode unit includes a corresponding dielectric element 15 and a corresponding temperature sensor 14, the multiple temperature sensors 14 are also arranged in four rows and five columns for circuit connection, and the multiple dielectric elements 15 are also arranged in four rows and five columns for circuit connection. It should be noted that the arrangement here is to more clearly show the electrical connection between the electrode sheet 10 and the adapter 20, and does not represent the arrangement of the electrode unit 12 in the spatial structure. The spatial structure may be as follows: Figure 1 The structure shown is generally an array, but may also be other structures, such as petal-shaped or scattered, and may be regular or irregular. The dielectric element 15 is configured to apply an alternating current signal to the patient's tumor site. The temperature sensor 14 is configured to detect the temperature of the patient's body surface to which the electrode sheet 10 is applied and output the temperature detection signal to the adapter 20. In this embodiment, the multiplexed signal lines 19 of the flexible circuit board 11 are respectively provided in a one-to-one correspondence with the multiple column groups of the electrode units 12, and are configured to transmit the alternating current signal generated by the electric field generator 30 to the dielectric elements 15 in each electrode unit 12 in the corresponding column group. That is, the dielectric elements 15 in the same column group are short-circuited by the same dual-purpose signal line 19 of the flexible circuit board 11, and the dielectric elements 15 in different column groups are connected in parallel by different dual-purpose signal lines 19 of the flexible circuit board 11. The dual-purpose signal lines 19 of the flexible circuit board 11 are electrically connected to corresponding wires in the first cable 13, and then electrically connected to the electric field generator 30 via the adapter 20. In other words, the dual-purpose signal lines 19 of the flexible circuit board 11 receive the AC signal generated by the electric field generator 30 through the first cable 13 and the adapter 20.

[0098] Multiple grounding wires 18 are provided in a one-to-one correspondence with the multiple row groups of electrode units 12. These wires are used to sequentially short-circuit the temperature sensors 14 of each electrode unit 12 in each row group to ground. Specifically, the ground terminals 14-1 of the temperature sensors 14 in the same row group are all short-circuited via the same grounding wire 18 on the flexible circuit board 11. The ground terminals 14-1 of the temperature sensors 14 in different row groups are each connected to ground in parallel via different grounding wires 18 on the flexible circuit board 11. During the temperature detection period or in the second mode, only one of the multiple grounding wires 18 is connected at any one time; the remaining grounding wires are disconnected.

[0099] Each of the multiplexed dual-purpose signal lines 19 is further configured to transmit a DC signal to the temperature sensor 14 in each electrode unit 12 in the corresponding column group to collect and transmit the detected temperature signal. The signal terminals 14-2 of the temperature sensors 14 in different column groups are connected in parallel via different dual-purpose signal lines 19 on the flexible circuit board 11. The signal terminals 14-2 of the temperature sensors 14 in the same column group are all short-circuited to the same dual-purpose signal line 19 on the flexible circuit board 11. Specifically, each dual-purpose signal line 19 is configured to short-circuit the signal terminal 14-2 of the temperature sensor 14 in at most one electrode unit 12 in each row group to an external device for receiving detection signals. Each of the multiplexed dual-purpose signal lines 19 is connected to a different signal terminal 14-2 of each temperature sensor 14 to prevent duplicate signals from being subsequently output by the dual-purpose signal lines 19. That is, when the number of electrode units 12 in a row group is the same as the number of dual-purpose signal lines 19, each dual-purpose signal line 19 is electrically connected to the signal end 14-2 of the temperature sensor 14 of a different electrode unit 12 in the row group. When the number of electrode units 12 in a row group is less than the number of dual-purpose signal lines 19, at least one dual-purpose signal line 19 is not electrically connected to the signal end 14-2 of the temperature sensor 14 of an electrode unit 12, and each of the remaining dual-purpose signal lines 19 is electrically connected to the signal end 14-2 of the temperature sensor 14 of a different electrode unit 12 in the row group. In this embodiment, the external device for receiving the detection signal is an adapter 20. The dual-purpose signal lines 19 of the flexible circuit board 11 receive the DC signal from the adapter 20 or the electric field generator 30 via the first cable 13, and transmit the collected or detected temperature signal to the adapter 20, and then transmit it to the electric field generator 30 via the adapter 20.

[0100] In the embodiment, in the case that the temperature sensor 14 is arranged in each electrode unit 12 to detect the temperature, the number of conductive lines of the first cable 13 is reduced by the above-mentioned line design to avoid the increase of the thickness of the cable and the rigidity of the cable, and to avoid the increase of the number of conductive lines of the first cable 13 affecting the adhesion effect between the electrode sheet 10 and the corresponding body surface of the tumor site of the patient. The embedded ground lines 18 and the dual-purpose signal lines 19 in the flexible circuit board 11 are 9 lines in total. Specifically, in the embodiment, the embedded ground lines 18 in the flexible circuit board 11 are 4 lines, and the dual-purpose signal lines 19 are 5 lines.

[0101] In the tumor electric field treatment system 100, the number of conductive lines electrically connected with the ground lines 18 is related to the number of row groups M of the electrode units 12, which can be greater than or equal to the number of row groups of the electrode units 12, and M is a positive integer. In the tumor electric field treatment system 100, the number of conductive lines electrically connected with the dual-purpose signal lines 19 is related to the number of column groups N of the electrode units 12, which can be greater than or equal to the number of column groups of the electrode units 12, and N is a positive integer. The number of lines L embedded in the flexible circuit board 11 of the electrode sheet 10 is equal to the sum of the number of ground lines 18 and the number of dual-purpose signal lines 19. In the embodiment, the number of ground lines 18 is equal to the number of row groups M of the electrode units 12; the number of dual-purpose signal lines 19 is equal to the number of column groups N of the electrode units 12.

[0102] In Figure 3 In the embodiment, specifically, the electrode sheet 10 of the embodiment includes 4 ground lines 18, each of which is used to ground the ground terminals 14-1 of the temperature sensors 14 in the same row group. The 4 ground lines 18 of the electrode sheet 10 are respectively a first ground line 18-1, a second ground line 18-2, a third ground line 18-3, and a fourth ground line 18-4. In the 4 row groups of the electrode sheet 10, the first row group includes the electrode units 12-1 to 12-5, the second row group includes the electrode units 12-6 to 12-10, the third row group includes the electrode units 12-11 to 12-15, and the fourth row group includes the electrode units 12-16 to 12-20. Specifically, the first ground line 18-1 is used to ground the electrode units 12-1 to 12-5 in the first row group; the second ground line 18-2 is used to ground the electrode units 12

[0103] 6 to electrode unit 12-10 is grounded; the third grounding wire 18-3 is used to ground electrode unit 12-11 to electrode unit 12-15 in the third row group; the fourth grounding wire 18-4 is used to ground electrode unit 12-16 to electrode unit 12-20 in the fourth row group. It should be noted that these grounding wires 18 can be selectively closed or disconnected, which can be achieved by connecting each grounding wire 18 in series with a switch, which will be described in detail below. The above-mentioned "grounding the electrode unit 12" can refer to grounding the ground terminal 14-1 of the temperature sensor 14 in the electrode unit 12, or it can refer to connecting the diode 16 in series with the temperature sensor 14 of the same electrode unit 12 and grounding them together. In short, each grounding wire 18 short-circuits the ground terminal 14-1 of the temperature sensor 14 of all electrode units 12 in each row group and grounds them.

[0104] Continue to refer Figure 3 As shown, the electrode sheet 10 of this embodiment also includes five dual-purpose signal lines 19. One end of each dual-purpose signal line 19 is connected to all electrode units 12 in each column group, and the other end is connected to an adapter 20 for receiving temperature detection signals and transmitting AC signals. In other words, for each row group, each dual-purpose signal line 19 can choose to connect to one of the electrode units 12 or not connect to any electrode unit 12 in the row group to avoid the dual-purpose signal line 19 subsequently outputting duplicate signals. Specifically, the five dual-purpose signal lines 19 of the electrode sheet 10 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the four electrode units 12, the electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-11, and the electrode unit 12-16, and the signal end 14-2 of the temperature sensor 14; one end of the second dual-purpose signal line 19-2 is connected to the electrode unit 12-2, the electrode unit 12-11, and the electrode unit 12-16.

[0105] 7. The dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-12 and electrode unit 12-17, and the signal terminals 14-2 of the temperature sensors 14; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-3, electrode unit 12-8, electrode unit 12-13, and electrode unit 12-18, and the signal terminals 14-2 of the temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-4, electrode unit 12-9, electrode unit 12-14, and electrode unit 12-19, and the signal terminals 14-2 of the temperature sensors 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-5, electrode unit 12-10, electrode unit 12-15, and electrode unit 12-20, and the signal terminals 14-2 of the temperature sensors 14. In short, each dual-purpose signal line 19 parallel-circuits the dielectric elements 15 and signal terminals 14-2 of the temperature sensors 14 within the same column group, allowing connection to an external device. It should be noted that these dual-purpose signal lines 19 can selectively transmit AC signals or receive temperature detection signals. This is achieved by connecting each dual-purpose signal line 19 in series with a bidirectional switch 26 and coordinating the opening and closing of the ground line 18. This will be described in detail below.

[0106] Multiple ground lines 18 and multiplexed signal lines 19 are conductive traces embedded within the flexible printed circuit board 11. The flexible printed circuit board 11 is electrically connected to the first cable 13. The multiple ground lines 18 and multiplexed signal lines 19 embedded within the flexible printed circuit board 11 are electrically connected to corresponding wires (not shown) within the first cable 13.

[0107] The tumor electric field therapy system 100 of this embodiment includes at least one pair of the above-mentioned electrode sheets 10, an adapter 20 electrically connected to the electrode sheets 10, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode sheets 10 and the electric field generator 30. The electric field generator 30 provides an AC signal or a DC signal to the dielectric elements 15 in the multiple electrode units 12 of the electrode sheet 10 via the adapter 20 and the dual-purpose signal line 19 of the electrode sheet 10, and is used to receive temperature detection signals output by the temperature sensors 14 in the multiple electrode units 12. The adapter 20 is configured to transmit the AC signal generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode sheet 10, and is also configured to transmit a DC signal to the dual-purpose signal line 19 of the electrode sheet and receive the temperature detection signal output by the multiple dual-purpose signal line 19 of the electrode sheet 10.

[0108] refer to Figure 3 and Figure 4 As shown, the adapter 20 includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of voltage transformers 24 corresponding to the multiple groups of analog-to-digital converters 23, multiple groups of grounding switches 25 and multiple groups of bidirectional switching switches 26, a first communication unit 27, multiple AC signal lines 28 connected to the multiple groups of bidirectional switching switches 26 in a one-to-one manner, and a first power supply module 29 connected to the first communication unit 27, the first controller 22 and the multiple groups of analog-to-digital converters 23. The first power supply module 29 provides a DC power supply VCC for each electronic component of the adapter 20. The adapter 20 also includes multiple circuit lines (unnumbered). Taking the electrical connection between a single electrode sheet 10 and the adapter 20 as an example, the multiple circuit lines (unnumbered) are electrically connected to the multiple grounding lines 18 and the multiple dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode sheet 10 through the first cable 13 of the corresponding electrode sheet 10. The multiple circuit lines (unnumbered) include multiple AC signal lines 28 that transmit alternating current signals to corresponding electrode sheets 10 and are electrically connected to the multiplexed signal lines 19 within the flexible circuit boards 11 of the corresponding electrode sheets 10, multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiplexed signal lines 19 within the flexible circuit boards 11 of the corresponding electrode sheets 10 and are used to power the temperature sensors 14 of the electrode sheets 10 or transmit temperature detection signals for the electrode sheets 10, and multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiple ground lines 18 within the flexible circuit boards 11 of the corresponding electrode sheets 10. The number P of circuit lines electrically connected by the adapter 20 to one electrode sheet 10 is equal to the sum of the number of rows M and the number of columns N of the electrode units 12 of the electrode sheet 10 plus 1; the number H of circuit lines electrically connected by the adapter 20 to X electrode sheets 10 is equal to X times the number of circuit lines electrically connected to a single electrode sheet 10, that is, H = XP = X*(M+N+1). The number of grounding switches 25 and the number of bidirectional switches 26 are both related to the number of electrode sheets 10. The number of grounding switches 25 and the number of bidirectional switches 26 are the same and no less than the number of electrode sheets 10. Preferably, the number of grounding switches 25 and the number of bidirectional switches 26 are both the same as the number of electrode sheets 10. The following detailed description will only use the example of an electrode sheet 10 having 20 electrode units 12 and the adapter 20 for electrical connection.

[0109] Each group of grounding switches 25 is provided with a plurality of grounding switches 25, and the plurality of grounding switches 25 are respectively connected to the adapter 20 and are respectively electrically connected to the circuit lines (not numbered) corresponding to the multi-way grounding lines 18 of the corresponding electrode sheet 10, and are configured to control the conduction or disconnection of the multi-way grounding lines 18. The circuit lines (not numbered) that are electrically connected to the multi-way grounding lines 18 of the electrode sheet 10 are grounded at one end close to the grounding switch 25. The number of grounding switches 25 in each group of grounding switches 25 is related to the number of grounding lines 18 of the flexible circuit board 11 of the corresponding electrode sheet 10, and the two are equal in this embodiment. Figure 3 As shown, in this embodiment, each group of grounding switches 25 is provided with a plurality of grounding switches 25, which are four in this embodiment, namely the first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3 and the fourth grounding switch 25-4. The plurality of grounding switches 25 in each group respectively control the closing or disconnection of the corresponding grounding line 18 of the corresponding electrode sheet 10. Specifically, the first grounding switch 25-1 is used to control the closing or disconnection of the first grounding line 18-1 of the corresponding electrode sheet 10, and then cooperates with the corresponding group of two-way switching switches 26 to control the power on and off of each temperature sensor 14 of the five electrode units 12 from electrode unit 12-1 to electrode unit 12-5 in the first row group of the electrode sheet 10; the second grounding switch 25-2 is used to control the closing or disconnection of the second grounding line 18-2 of the electrode sheet 10, and then cooperates with the corresponding group of two-way switching switches 26 to control the power on and off of each temperature sensor 14 of the five electrode units 12 from electrode unit 12-6 to electrode unit 12-10 in the second row group of the electrode sheet 10. The third grounding switch 25-3 is used to control the closing or disconnection of the third grounding line 18-3 of the electrode sheet 10, and can then cooperate with the corresponding group of two-way switching switches 26 to control the power on and off of each temperature sensor 14 of the five electrode units 12 in the third row group of the electrode sheet 10, from electrode unit 12-11 to electrode unit 12-15; the fourth grounding switch 25-4 is used to control the closing or disconnection of the fourth grounding line 18-4 of the electrode sheet 10, and can then cooperate with the corresponding group of two-way switching switches 26 to control the power on and off of each temperature sensor 14 of the five electrode units 12 in the fourth row group of the electrode sheet 10, from electrode unit 12-16 to electrode unit 12-20. The above-mentioned grounding switch 25 can be a mechanical switch, such as a relay. The grounding switch 25 can also be an electronic switch, and each grounding switch 25 can be opened and closed by the first controller 22 of the adapter 20.

[0110] In this embodiment, the multiple groups of grounding switches 25 are all electronic switches. The first controller 22 is in communication with the multiple groups of grounding switches 25 and is configured to sequentially and cyclically control the opening and closing states of the multiple grounding switches 25 in each group of grounding switches 25. This in turn sequentially connects each of the multiple grounding wires 18 of the corresponding electrode sheet 10 and coordinates the switching of the corresponding bidirectional switch 26 to sequentially and time-share the patient's body surface temperature detected by all temperature sensors 14 on the electrode sheet 10. The number of grounding switches 25 in each group is greater than or equal to the number of grounding wires 18 on the flexible circuit board 11 of the corresponding electrode sheet 10. In this embodiment, the number of grounding switches 25 in each group is the same as the number of grounding wires 18 of the corresponding electrode sheet 10.

[0111] Each set of two-way switches 26 is provided with a plurality of two-way switches 26. The plurality of two-way switches 26 in each set are respectively connected to the adapter 20 and are respectively electrically connected to the circuit lines (not numbered) corresponding to the multiplexed dual-purpose signal lines 19 of the corresponding electrode sheet 10. The number of two-way switches 26 in each set of two-way switches 26 is related to the number of dual-purpose signal lines 19 of the flexible circuit board 11 of the corresponding electrode sheet 10, and is greater than or equal to the number of dual-purpose signal lines 19 of the flexible circuit board 11 of the corresponding electrode sheet 10. Figure 3 In the illustrated embodiment, the two are equal. Each bidirectional switch 26 has two terminals labeled 1 and 2. The acquisition terminals 1 of the multiple bidirectional switches 26 in the same group are electrically connected to corresponding detection channels of the multiple detection channels of the corresponding group of analog-to-digital converters 23. The input terminals 2 of each bidirectional switch 26 in the same group are electrically connected to the same corresponding AC signal line 28. Each bidirectional switch 26 is configured to control whether the multiplexed signal line 19 is connected to the corresponding AC signal line 28 to transmit an alternating current signal, or to the corresponding detection channel of the corresponding group of analog-to-digital converters 23 to receive the temperature detection signal output by the temperature sensor 14.

[0112] like Figure 3As shown, taking the example of the electrical connection of one electrode sheet 10 with the adapter 20, in the present embodiment with 20 electrode units 12, the multiple bidirectional switches 26 are respectively a first bidirectional switch 26-1, a second bidirectional switch 26-2, a third bidirectional switch 26-3, a fourth bidirectional switch 26-4, and a fifth bidirectional switch 26-5. The multiple bidirectional switches 26 in the same group respectively control the switching of a corresponding one of the multiple two-purpose signal lines 19 of the same electrode sheet 10 between the transmission of the alternating current signal and the transmission of the temperature detection signal. Specifically, the first bidirectional switch 26-1 is used to control the switching of the first two-purpose signal line 19-1 of the corresponding electrode sheet 10 between the transmission of the alternating current signal and the transmission of the temperature detection signal, thereby controlling the switching between the conduction of the dielectric element 15 of the electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-11, the electrode unit 12-16 in the first column group of the electrode sheet 10 and the conduction of the signal end 14-2 of the temperature sensor 14 of the electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-11, the electrode unit 12-16 in the first column group, and cooperating with the corresponding first ground switch 25-1, the second ground switch 25-2, the third ground switch 25-3, the fourth ground switch 25-4, so that the first column of electrode units 12-1, 12-6, 12-11, 12-16 transmits the alternating current signal to the patient or outputs the temperature detection signal collected by the temperature sensor 14 of the electrode units 12 to the corresponding analog-to-digital converter 23; the second bidirectional switch 26-2 is used to control the switching of the second two-purpose signal line 19-2 of the corresponding electrode sheet 10 between the transmission of the alternating current signal and the transmission of the temperature detection signal, thereby controlling the switching between the conduction of the dielectric element 15 of the electrode unit 12-2, the electrode unit 12-7, the electrode unit 12-12, the electrode unit 12-17 in the second column group of the electrode sheet 10 and the conduction of the signal end 14-2 of the temperature sensor 14 of the electrode unit 12-2, the electrode unit 12-7, the electrode unit 12-12, the electrode unit 12-17 in the second column group, and cooperating with the corresponding first ground switch 25-1, the second ground switch 25-2, the third ground switch 25-3, the fourth ground switch 25-4, so that the second column of electrode units 12-2, 12-7, 12-12, 12-17 transmits the alternating current signal to the patient or outputs the temperature detection signal collected by the temperature sensor 14 of the electrode units 12 to the corresponding analog-to-digital converter 23;The third bidirectional switch 26-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode sheet 10 between transmitting an AC signal and transmitting a temperature detection signal, thereby controlling the switching between the conduction of the dielectric elements 15 of the electrode units 12-3, 12-8, 12-13, and 12-18 in the third column group of the electrode sheet 10 and the conduction of the signal terminals 14-2 of the temperature sensors 14 of the electrode units 12-3, 12-8, 12-13, and 12-18 in the third column group, and cooperating with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, so that the third column of electrode units 12-3, 12-8, 12-13, and 12-18 transmits an AC signal to the patient or outputs the temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23. The fourth bidirectional switch 26-4 is used to control the switching between the transmission of the AC signal and the transmission of the temperature detection signal by the fourth dual-purpose signal line 19-4 of the corresponding electrode sheet 10, thereby controlling the conduction of the dielectric elements 15 of the electrode units 12-4, 12-9, 12-14, and 12-19 in the fourth column group of the electrode sheet 10 and the conduction of the signal terminals 14-2 of the temperature sensors 14 of the electrode units 12-4, 12-9, 12-14, and 12-19 in the fourth column group, and cooperating with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, so that the fourth column of electrode units 12-4, 12-9, 12-14, and 12-19 transmits the AC signal to the patient or outputs the temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the analog-to-digital converter 23;The fifth bidirectional switch 26-5 is used to control the switching of the fifth dual-purpose signal line 19-5 of the corresponding electrode sheet 10 between transmitting alternating current signals and transmitting temperature detection signals, thereby controlling the conduction of the dielectric elements 15 of the electrode units 12-5, 12-10, 12-15, and 12-20 in the fifth column group of the electrode sheet 10 and the conduction of the signal ends 14-2 of the temperature sensors 14 of the electrode units 12-5, 12-10, 12-15, and 12-20 in the fifth column group, and cooperating with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, so that the fifth column of electrode units 12-5, 12-10, 12-15, and 12-20 transmit alternating current signals to the patient or output the temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23. When the input terminal 2 of each set of bidirectional switches 26 is on and the acquisition terminal 1 is off, an AC signal can be transmitted to the dielectric element 15 of each electrode unit 12 of the corresponding electrode sheet 10. When the acquisition terminal 1 of each set of bidirectional switches 26 is on and the input terminal 2 is off, the switches 26 can cooperate with each of the corresponding set of grounding switches 25 to time-share the temperature detection signals collected by the temperature sensors 14 of each electrode unit 12 on the electrode sheet 10. The bidirectional switches 26 can be mechanical switches, such as relays. Alternatively, they can be electronic switches. The switching between the acquisition terminal 1 and the input terminal 2 of each bidirectional switch 26 can be controlled by the first controller 22 of the adapter 20.

[0113] In this embodiment, the plurality of sets of bidirectional switches 26 are all electronic switches. The first controller 22 is in communication with the plurality of sets of bidirectional switches 26 and is configured to control the plurality of bidirectional switches 26 in each set of bidirectional switches 26 to switch between their respective acquisition terminals 1 and input terminals 2, and to coordinate with the closing or opening of the corresponding grounding switches 25 to continuously monitor the patient's body surface temperature detected by all temperature sensors 14 on the electrode sheet 10 or to transmit an AC signal to the patient.

[0114] In this embodiment, each group of analog-to-digital converters 23 is electrically connected to the collection terminals 1 of the multiple bidirectional switching switches 26 in the corresponding group of bidirectional switching switches 26 through the multi-channel circuit lines (unnumbered) in the adapter 20, and is configured to receive the temperature detection signal transmitted by the multiplexed signal line 19 of the corresponding electrode sheet 10, and convert the temperature detection signal from an analog signal to a digital signal. Each group of analog-to-digital converters 23 includes multiple detection channels A, B, C, D, and E, and each detection channel A, B, C, D, and E is used to connect to a corresponding one-way dual-purpose signal line 19 in the multiplexed signal line 19 through the corresponding bidirectional switching switch 26. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of bidirectional switching switches 26 in the corresponding group. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of column groups of electrode units 12 of the corresponding electrode sheet 10. Specifically, the number of detection channels in each group of analog-to-digital converters 23 is equal to the number of bidirectional switches 26 in the corresponding group of bidirectional switches 26, which is not less than the number of columns of electrode units 12 of the corresponding electrode sheet 10. Figure 3 As shown, each set of analog-to-digital converters 23 includes a total of five detection channels A, B, C, D, and E, namely the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1 via the acquisition terminal 1 of the first bidirectional switch 26-1, the second detection channel B is connected to the second dual-purpose signal line 19-2 via the acquisition terminal 1 of the second bidirectional switch 26-2, the third detection channel C is connected to the third dual-purpose signal line 19-3 via the acquisition terminal 1 of the third bidirectional switch 26-3, the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 via the acquisition terminal 1 of the fourth bidirectional switch 26-4, and the fifth detection channel E is connected to the fifth dual-purpose signal line 19-5 via the acquisition terminal 1 of the fifth bidirectional switch 26-5. Each detection channel A, B, C, D, and E is used to receive the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 connected to the corresponding dual-purpose signal line 19. In addition, each detection channel A, B, C, D, E is connected to a first power module 29 for providing a detection voltage to the detection channel A, B, C, D, E via a corresponding voltage divider resistor 24 in the adapter 20. The first power module 29 provides a DC signal.

[0115] In this embodiment, the first communication unit 27 is configured to obtain the digital signals output by the multiple analog-to-digital converters 23 and send the digital signals to the electric field generator 30. The electric field generator 30 is also configured to control and adjust the voltage, current, or power of the AC signal provided to the multiple electrode units 12 of the electrode sheet 10 based on the received digital signals. For example, when any of the multiple digital signals received exceeds a preset threshold, it indicates that the temperature of the human body surface to which the corresponding dielectric element 15 is applied, detected by at least one temperature sensor 14 in the electrode sheet 10, exceeds a preset threshold temperature (e.g., 41°C, 42°C, etc.). At this time, the voltage, current, or power of the AC signal output by the electric field generator 30 can be appropriately reduced to prevent the electrode units 12 of the electrode sheet 10 from becoming too hot when the AC signal is applied, thereby causing low-temperature burns to the patient's skin. The above-mentioned preset threshold temperature and preset threshold value can be determined based on the human body safety threshold. The first communication unit 27 is controlled by the first controller 22 and serially transmits the digital signals converted by the multiple analog-to-digital converters 23. In this embodiment, the preset temperature threshold may be a value within the range of 36°C-45°C.

[0116] refer to Figure 4 as well as Figure 5 In this embodiment, the first power supply module 29 is electrically connected to the second power supply module 31 of the electric field generator 30 and is configured to supply power to the first controller 22, the multiple analog-to-digital converters 23, and the first communication unit 27 of the adapter 20. A first connector 40 is provided between each electrode sheet 10 and the adapter 20. The first connector 40 is suitable for connecting the corresponding electrode sheet 10 to the adapter 20. Figure 1 As shown, the first connector 40 includes a first plug 41 located at the end of the first cable 13 away from the electrode sheet 10, and a first socket 42 located on the adapter 20. The first plug 41 and the first socket 42 are spring-loaded connectors, meaning that the first connector 40 connects the adapter 20 to the electrode sheet 10 using a connector. Each first cable 13 has five wires electrically connected to the bidirectional switches 26 in a corresponding group of bidirectional switches 26, and four wires electrically connected to the grounding switches 25 in a corresponding group of grounding switches 25. In other words, each first connector 40 is electrically connected to a corresponding group of bidirectional switches 26-1, 26-2, 26-3, 26-4, and 26-5 and a corresponding group of grounding switches 25-1, 25-2, 25-3, and 25-4 of the adapter 20 via nine wires, and is connected to the electric field generator 30 via a corresponding AC signal line 28 of the adapter 20.

[0117] A second connector 50 is provided between the adapter 20 and the electric field generator 30. The second connector 50 is adapted to connect the electric field generator 30 to the adapter 20. The adapter 20 also includes a second cable 21 connected to the second connector 50. The second connector 50 includes a second plug 51 located at the end of the second cable 21 away from the first controller 22 and a second socket 52 located on the electric field generator 30. The second plug 51 and the second socket 52 are spring-loaded connectors, meaning that the second connector 50 connects the adapter 20 to the electric field generator 30 using a connector-type design. Each first connector 40, such as X1, Y1, X2, and Y2, is connected to the second connector 50 via a corresponding AC signal line 28. Each first connector 40, such as X1, Y1, X2, and Y2, connects a corresponding set of grounding switches 25 to a corresponding set of analog-to-digital converters 23. Specifically, each first connector 40 is simultaneously connected to the second connector 50 and a corresponding set of analog-to-digital converters 23 via a corresponding set of bidirectional switches 26. Taking four electrode sheets 10 as an example, the second cable 21 has eight conductors: four conductors 1 to 4 electrically connected to corresponding AC signal lines 28 for transmitting AC signals; one conductor 5 electrically connected to the data receiving line RX of the first communication unit 27; one conductor 6 electrically connected to the data transmitting line TX of the first communication unit 27; one conductor 7 electrically connected to the VCC power line of the first power module 29; and one conductor 8 electrically connected to the GND line of the first power module 29. A second connector 50 is connected to the first communication unit 27 via the data receiving line RX and the data transmitting line TX. The VCC pin of the second connector 50 is connected to the VVC power line of the first power module 29, and the GND pin of the second connector 50 is connected to the GND line of the first power module 29 and is grounded. The VCC pin of the second connector 50 is also connected to the corresponding set of voltage dividers 24 and the corresponding set of analog-to-digital converters 23 via the VCC power line of the first power module 29.

[0118] refer to Figure 5The electric field generator 30 includes a second power module 31, a second controller 32, an AC signal generator 34, a second communication unit 33, and a set of AC signal switches 35. The VCC pin of the second connector 50 is also electrically connected to the VCC power line of the second power module 31, and the GND pin of the second connector 50 is grounded through the GND line of the second power module 31. The second power module 31 is also connected to the second controller 32 and the AC signal generator 34 and supplies power to them. The second communication unit 33 is electrically connected to the wire 5 of the second connector 50 via its data receiving line RX and to the wire 6 of the second connector 50 via its data transmitting line TX, thereby enabling information exchange between the electric field generator 30 and the adapter 20. The second controller 32 is also electrically connected to the second communication unit 33, the AC signal generator 34, and the set of AC signal switches 35. The second controller 32 is configured to control the opening and closing of each AC signal switch 35 in a group of AC signal switches 35 and adjust the relevant parameters of the AC signal applied by the AC signal generator 34 according to the relevant digital signal received from the adapter 20 by the second communication unit 33. The AC signal generator 34 is electrically connected to the wires 1 to 4 of the second connector 50 that transmit the AC signal through the group of AC signal switches 35. A group of AC signal switches 35 includes a plurality of AC signal switches 35, and the plurality of AC signal switches 35 are arranged in a one-to-one correspondence with the plurality of electrode sheets 10. Each AC signal switch 35 is electrically connected to a corresponding wire 1, 2, 3, 4 that transmits the AC signal in the second connector 50 through an AC signal connection 36 and is electrically connected to the corresponding electrode sheet 10 through the corresponding wire 1, 2, 3, 4 of the second connector 50, so as to transmit the AC signal to each electrode sheet 10. The AC signal generator 34 is electrically connected to the group of AC signal switches 35 through a group of AC signal connections 36.

[0119] Specifically, the number of AC signal switches 35 of the electric field generator 30 is related to the number of electrode sheets 10. In this embodiment, the number of AC signal switches 35 is equal to the number of electrode sheets 10, and both are four. The AC signal switches 35 include a first AC signal switch 35-1, a second AC signal switch 35-2, a third AC signal switch 35-3, and a fourth AC signal switch 35-4, which are electrically connected to the wires 1 to 4 of the second connector 50 through corresponding AC signal wiring 36, respectively.One end of the first AC signal switch 35-1 is electrically connected to the AC signal generator 34 through the first AC signal connection 36-1 of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 1 for transmitting AC signals in the second connector 50 through the first AC signal connection 36-1 and electrically connected to the AC signal line 28 at the port X1 of the adapter 20 through the conductor 1 of the second connector 50, the AC signal line 28 at the port X1 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port X1 of the adapter 20 is electrically connected to the corresponding electrode sheet 10, so as to control whether the AC signal generator 34 transmits an AC signal to the electrode sheet 10 electrically connected to the port X1 of the adapter 20; One end of the second AC signal switch 35-2 is electrically connected to the AC signal generator 34 through the second AC signal connection 36-2 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 2 for transmitting AC signals in the second connector 50 through the second AC signal connection 36-2 and electrically connected to the AC signal line 28 at the port Y1 of the adapter 20 through the wire 2 of the second connector 50, the AC signal line 28 at the port Y1 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port Y1 of the adapter 20 is electrically connected to the corresponding electrode sheet 10, so as to control whether the AC signal generator 34 transmits AC signals to the electrode sheet 10 electrically connected to the port Y1 of the adapter 20; One end of the third AC signal switch 35-3 is electrically connected to the AC signal generator 34 through the third AC signal connection 36-3 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 3 for transmitting AC signals in the second connector 50 through the third AC signal connection 36-3 and electrically connected to the AC signal line 28 at the port X2 of the adapter 20 through the wire 3 of the second connector 50, the AC signal line 28 at the port X2 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port X2 of the adapter 20 is electrically connected to the corresponding electrode sheet 10, so as to control whether the AC signal generator 34 transmits the AC signal to the electrode sheet 10 electrically connected to the port X2 of the adapter 20; One end of the fourth AC signal switch 35-4 is electrically connected to the AC signal generator 34 through the fourth AC signal connection 36-4 of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 4 for transmitting AC signals in the second connector 50 through the fourth AC signal connection 36-4 and electrically connected to the AC signal line 28 at the port Y2 of the adapter 20 through the conductor 4 of the second connector 50, the AC signal line 28 at the port Y2 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port Y2 of the adapter 20 is electrically connected to the corresponding electrode sheet 10, so as to control whether the AC signal generator 34 transmits AC signals to the electrode sheet 10 electrically connected to the port Y1 of the adapter 20.

[0120] The following will refer to Figures 3 to 5 The working principle of the tumor electric field treatment system 100 of this embodiment is described in detail.

[0121] Specifically, when it is necessary to detect the temperature of each electrode unit 12 of a certain electrode sheet 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls the collection end 1 of each of the multiple bidirectional switching switches 26 of a group of bidirectional switching switches 26 electrically connected to the electrode sheet 10 to be turned on and the input end 2 to be disconnected, so as to disconnect the AC signal applied to the electrode sheet 10; at the same time, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls each of the grounding switches 25 in a group of grounding switches 25 electrically connected to the electrode sheet 10 to be turned on in sequence. At this time, the temperature detection signals collected by each temperature sensor 14 of each electrode unit 12 of each row group of the electrode sheet 10 can be collected in sequence through multiple detection channels A, B, C, D, and E of a group of analog-to-digital converters 23 corresponding to the electrode sheet 10. Each detection channel A, B, C, D, and E of each group of analog-to-digital converters 23 simultaneously collects only the temperature detection signals of the temperature sensors 14 corresponding to the electrode units 12 of the electrode sheet 10 in the same row group. The temperature detection signals can be represented by voltage values, indicating that only one of the four grounding switches 25 in the group of grounding switches 25 corresponding to the electrode sheet 10 is turned on at the same time, while the other three are turned off. All five bidirectional switches 26 in the group of bidirectional switches 26 corresponding to the group of analog-to-digital converters 23 are switched to their respective collection terminals 1 so that the dual-purpose signal lines 19 of the electrode sheet 10 are electrically connected to the corresponding detection channels A, B, C, D, and E of the corresponding group of analog-to-digital converters 23 in a one-to-one correspondence and are turned on. With this arrangement, the group of analog-to-digital converters 23 can collect the voltage values ​​of the temperature sensors 14 of the electrode units 12 in the same row group that are short-circuited with the grounding line 18 corresponding to the turned-on grounding switch 25.

[0122] Specifically, when the first grounding switch 25-1 is closed, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 are all opened, and the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5 are all switched to their respective acquisition terminals 1, the temperature sensors 14 of the electrode units 12-1 to 12-5 of the first row group are powered on, and the temperature sensors 14 of the electrode units 12-6 to 12-20 of the remaining row groups are powered off, and the first detection channel A in the analog-to-digital converter 23 of the group short-circuits the electrode units 12-1, 12-6, 12-11, and 12-16, respectively. Regarding the signal terminal 14-2 of the temperature sensor 14 of electrode unit 12-1, only the ground terminal 14-1 of the temperature sensor 14 of electrode unit 12-1 is connected to ground, while the ground terminals 14-1 of the temperature sensors 14 of electrode units 12-6, 12-11, and 12-16 are all disconnected. Furthermore, each electrode unit 12 is provided with a diode 16 connected in series with the temperature sensor 14. The remaining temperature sensors 14 in the first row do not affect the resistance of the temperature sensor 14 of electrode unit 12-1. Therefore, only the temperature sensor 14 of electrode unit 12-1 is effectively operating on the first detection channel A of the group of analog-to-digital converters 23. The temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of electrode unit 12-1. Similarly, the voltage value collected by the second detection channel B of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-2. The voltage value collected by the third detection channel C of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-3. The voltage value collected on the fourth detection channel D of the ADC 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-4. The voltage value collected on the fifth detection channel E of the ADC 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-5.

[0123] When the second grounding switch 25-2 is closed, the first grounding switch 25-1, the third grounding switch 25-3 and the fourth grounding switch 25-4 are all opened, and the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 are all switched to their respective acquisition terminals 1, the temperature sensors 14 of the electrode units 12-6 to 12-10 of the second row group are powered on, and the temperature sensors 14 of the electrode units 12-1 to 12-5 and the electrode units 12-11 to 12-20 of the remaining row groups are powered off, and the first detection channel A in the analog-to-digital converter 23 of the group short-circuits the electrode units 12-1, 12-6 and 12-20.

[0124] 11. The signal end 14-2 of the temperature sensor 14 of each of the electrode units 12-16 is connected to the ground because only the ground end 14-1 of the temperature sensor 14 of the electrode unit 12-6 is connected to the ground, and the ground ends 14-1 of the temperature sensors 14 of the electrode units 12-1, 12-11 and 12-16 are disconnected, and each electrode unit 12 is provided with a diode 16 connected in series with the temperature sensor 14. The remaining temperature sensors 14 in the second row will not affect the resistance value of the temperature sensor 14 of the electrode unit 12-6. Therefore, only the temperature sensor 14 of the electrode unit 12-6 is effectively operating on the first detection channel A of the analog-to-digital converter 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the temperature detection signal of the electrode unit 12-1.

[0125] 6. Similarly, the voltage value collected on the second detection channel B in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-7. The voltage value collected on the third detection channel C in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-8. The voltage value collected on the fourth detection channel D in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-9. The voltage value collected on the fifth detection channel E in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-10.

[0126] When the third grounding switch 25-3 is closed, the first grounding switch 25-1, the second grounding switch 25-2 and the fourth grounding switch 25-4 are all opened, and the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 are all switched to their respective acquisition terminals 1, the temperature sensors 14 of the electrode units 12-11 to 12-15 of the third row group are powered on, and the temperature sensors 14 of the electrode units 12-1 to 12-10 and the electrode units 12-16 to 12-20 of the remaining row groups are powered off, and the first detection channel A in the analog-to-digital converter 23 of the group short-circuits the electrode units 12-1, 12-6 and 12-20.

[0127] 11. The signal end 14-2 of the temperature sensor 14 of each of the electrode units 12-16 is connected to the ground because only the ground end 14-1 of the temperature sensor 14 of the electrode unit 12-11 is connected to the ground, and the ground ends 14-1 of the temperature sensors 14 of the electrode units 12-1, 12-6 and 12-16 are disconnected, and each electrode unit 12 is provided with a diode 16 connected in series with the temperature sensor 14. The remaining temperature sensors 14 located in the third row will not affect the resistance value of the temperature sensor 14 of the electrode unit 12-11. Therefore, only the temperature sensor 14 of the electrode unit 12-11 is effectively operating on the first detection channel A of the analog-to-digital converter 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the temperature detection signal of the electrode unit 12-12.

[0128] 11. Similarly, the voltage value collected on the second detection channel B in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-12. The voltage value collected on the third detection channel C in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-13. The voltage value collected on the fourth detection channel D in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-14. The voltage value collected on the fifth detection channel E in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-15.

[0129] When the fourth grounding switch 25-4 is closed, the first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 are all opened, and the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 are all switched to their respective acquisition terminals 1, the temperature sensors 14 of the electrode units 12-16 to 12-20 of the fourth row group are powered on, and the temperature sensors 14 of the electrode units 12-1 to 12-15 of the remaining row groups are powered off, and the first detection channel A in the analog-to-digital converter 23 of the group short-circuits the temperature sensors of the electrode units 12-1, 12-6, 12-11 and 12-16. Since only the ground terminal 14-1 of the temperature sensor 14 of electrode unit 12-16 is connected to the ground, and the ground terminals 14-1 of the temperature sensors 14 of electrode unit 12-1, electrode unit 12-6, and electrode unit 12-11 are all disconnected, and each electrode unit 12 is provided with a diode 16 connected in series with the temperature sensor 14, the remaining temperature sensors 14 in the fourth row will not affect the resistance value of the temperature sensor 14 of electrode unit 12-16. Therefore, only the temperature sensor 14 of electrode unit 12-16 is effectively operating on the first detection channel A of the group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of electrode unit 12-16. Similarly, the voltage value collected by the second detection channel B in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-17. The voltage value collected on the third detection channel C in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-18. The voltage value collected on the fourth detection channel D in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-19. The voltage value collected on the fifth detection channel E in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-20. Thus, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 can realize the collection of temperature detection signals of the temperature sensors 14 of all electrode units 12 of a certain electrode sheet 10 by controlling a group of bidirectional switching switches 26 and a group of grounding switches 25 that are electrically connected to the electrode sheet 10. Similarly, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of other electrode sheets 10 can be obtained.

[0130] The first controller 22, the plurality of analog-to-digital converters 23, and the plurality of bidirectional switches 26 can automatically perform operations according to pre-programmed program codes. For example, the first controller 22 first controls all the bidirectional switches 26 in the corresponding group of bidirectional switches 26 to switch to the acquisition terminal 1, so that the acquisition terminals 1 of the bidirectional switches 26 are all turned on and the input terminals 2 are all turned off, so that the dual-purpose signal lines 19 of the corresponding electrode sheets 10 are electrically connected to the corresponding group of analog-to-digital converters 23. Then, the first grounding switch 25-1 in the corresponding group of grounding switches 25 is closed, and the remaining second grounding switches 25-2, third grounding switches 25-3 to fourth grounding switches 25-4 in the group of grounding switches 25 are turned off. During this period, the group Each detection channel A, B, C, D, and E of the analog-to-digital converter 23 acquires the temperature detection signals of each temperature sensor 14 of each electrode unit 12 located in the first row group of the corresponding electrode sheet 10, converts them into digital signals, and stores them in a separately provided memory. Then, after a preset interval, the first controller 22 closes the second grounding switch 25-2 in the group of grounding switches 25 and opens the first grounding switch 25-1, the third grounding switch 25-3, and the fourth grounding switch 25-4 in the group of grounding switches 25. During this period, each detection channel A, B, C, D, and E of the analog-to-digital converter 23 acquires the temperature detection signals of each temperature sensor 14 of each electrode unit 12 located in the second row group. By sequentially opening each grounding switch 25 in the group of grounding switches 25, the temperature detection signals of all temperature sensors 14 located in each row group of the electrode sheet 10 can be obtained. Similarly, through this operation, the temperature detection signals of all temperature sensors 14 on at least one pair of electrode sheets 10 are obtained.

[0131] The tumor electric field therapy system 100 of the present application can realize real-time and comprehensive monitoring of the temperature of all electrode units 12 on the electrode sheet 10 without increasing the weight of the electrode sheet 10 or adding the core of the first cable 13 electrically connected to the electrode sheet 10, and then determine whether the electrode sheet 10 is qualified based on the obtained temperature detection signal; or determine whether the temperature sensor 14 of the electrode sheet 10 is faulty or abnormal based on the obtained temperature detection signal, and determine whether the electrode sheet 10 needs to be replaced based on the number of faulty or abnormal temperature sensors 14 obtained; or if the electrode sheet is qualified, identify the type of electrode sheet based on the obtained temperature detection signal; or if the electrode sheet is qualified, determine whether the electrode unit 12 of the electrode sheet 10 is overheated based on the obtained temperature detection signal, and then control the alternating electric signal applied to the electrode sheet 10 or the electrode unit 12 of the corresponding column of the electrode sheet 10, so as to avoid low-temperature burns on the patient's body surface when tumor treatment is performed through the electrode sheet 10. In addition, the flexible circuit board 11 of the electrode sheet 10 of the present application is electrically connected to the dielectric element 15 of the same electrode unit 12 and the signal terminal 14-2 of the temperature sensor 14 through the same dual-purpose signal line 19. While it can transmit both an AC signal and a DC signal for temperature signal acquisition and the collected temperature detection signal through the dual-purpose signal line 19, it also greatly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) arranged thereon, thereby reducing the wiring difficulty of the flexible circuit board 11, simplifying the manufacturing process, reducing the weight of the flexible circuit board 11, and reducing manufacturing costs. The electrode sheet 10 of the present application can also switch between applying an AC signal for tumor treatment and transmitting a DC signal for temperature acquisition and the collected temperature detection signal through the combined control of a grounding switch 25 electrically connected to the grounding line 18 arranged thereon and a bidirectional switching switch 26 electrically connected to the dual-purpose signal line 19.

[0132] When it is necessary to apply an alternating current signal to the patient through the electrode units 12 of a certain electrode sheet 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls all the grounding switches 25 in a group of grounding switches 25 corresponding to the electrode sheet 10 to be disconnected, and at the same time controls all the bidirectional switching switches 26 in a group of bidirectional switching switches 26 corresponding to the electrode sheet 10 to be switched to their respective input ends 2, so that the collection ends 1 of the bidirectional switching switches 26 are all disconnected and the input ends 2 are all turned on, so that the dual-purpose signal lines 19 of the electrode sheet 10 are electrically connected to the adapter 20 and an AC signal line 28 corresponding to the electrode sheet 10, thereby transmitting the alternating current signal to the electrode units 12 of the electrode sheet 10.When the temperature detection signals of the temperature sensors 14 of all the electrode units 12 of the electrode sheet 10 are much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 34 through its second controller 32 to continue to generate an AC signal with an increased voltage or current amplitude or a constant voltage or current amplitude, and then transmits it to the corresponding pair of electrode sheets 10 through a corresponding AC signal line 28 of the adapter 20, so that the pair of electrode sheets 10 continue to apply the AC signal; when the temperature detection signals of the temperature sensors 14 of all the electrode units 12 of the electrode sheet 10 are lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20, The electric field generator 30 can reduce the voltage or current of the alternating current signal generated by the AC signal generator 34 through the second controller 32, thereby reducing the voltage or current of the alternating current signal applied to the pair of electrode sheets 10; when it is detected that the temperature detection signal of the temperature sensor 14 of an electrode unit 12 in a certain electrode sheet 10 is greater than a preset temperature threshold, the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode sheet 10 to be disconnected through the second controller 32 to stop applying the alternating current signal to the electrode sheet 10; or the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls all the bidirectional switches in a group of bidirectional switches 26 electrically connected to the electrode sheet 10 The switches 26 are all switched from their input terminals 2 to the collection terminals 1, that is, all the collection terminals 1 of the two-way switching switches 26 electrically connected to the electrode sheet 10 are turned on and all the input terminals 2 are turned off, thereby stopping the application of the alternating electric signal to the electrode sheet 10; or, when it is detected that the temperature detection signal of the temperature sensor 14 of an electrode unit 12 of a certain electrode sheet 10 is greater than the preset temperature threshold, the second controller 32 of the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode sheet 10 to continue to be turned on, and the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls a two-way switch electrically connected to the electrode unit 12 of the electrode sheet 10 to be turned on. Switch 26 switches from its input terminal 2 to its acquisition terminal 1, and the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 simultaneously controls the input terminals 2 of the remaining bidirectional switches 26 electrically connected to the electrode units 12 of the electrode sheet 10 whose temperature detection signals do not exceed the preset temperature threshold and are in different columns from the electrode units 12 whose temperature detection signals exceed the preset temperature threshold to remain electrically connected. This stops applying the AC signal to all electrode units 12 in the column of the electrode unit 12 of the electrode sheet 10 whose temperature detection signals exceed the preset temperature threshold, and continues applying the AC signal to the electrode units 12 in the remaining columns of the electrode sheet 10 whose temperature detection signals do not exceed the preset temperature threshold. This implements the control method of the tumor electric field therapy system 100 for regional application of the AC signal based on the temperature detection signal.When an AC signal is applied, all grounding switches 25 are opened.

[0133] In the embodiment of the present application, the grounding switch 25 electrically connected to each of the multiple grounding lines 18 of the electrode sheet 10 and the bidirectional switch 26 electrically connected to each of the multiple dual-purpose signal lines 19 of the electrode sheet 10 are both provided in the adapter 20. However, in other embodiments, the grounding switch 25 electrically connected to the grounding line 18 and the bidirectional switch 26 electrically connected to the dual-purpose signal line 19 can also be provided on the electrode sheet 10 or provided in the electric field generator 30, which will not be described in detail here. In addition, the analog-to-digital converter 23 provided in the adapter 20 can also be provided in the electric field generator 30 and directly controlled by the second controller 32.

[0134] The present application also provides other embodiments of the electrode sheet 10 , and the differences among the multiple embodiments mainly lie in the different numbers of electrode units 12 and / or the different electrical connection arrangements of the electrode units 12 , which will be described below.

[0135] refer to Figure 6As shown, the electrode sheet 10A of the second embodiment is provided with 19 electrode units 12. A flexible printed circuit board 11A electrically arranges these 19 electrode units 12 into four rows and five columns. Three rows each have five electrode units 12, and the remaining row has four electrode units 12. The electrode sheet 10A includes four grounding wires 18 and five dual-purpose signal wires 19. Each grounding wire 18 is used to ground the ground terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 and the signal terminal 14-2 of each temperature sensor 14 in each column group, respectively, for receiving temperature detection signals or transmitting AC signals. The four grounding lines 18 of the electrode sheet 10A include a first grounding line 18-1, a second grounding line 18-2, a third grounding line 18-3 and a fourth grounding line 18-4. The first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-10, the third row group includes electrode units 12-11 to 12-15, and the fourth row group includes electrode units 12-16 to 12-19. Specifically, first grounding line 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the five electrode units 12 in the first row group, namely, electrode units 12-1 to 12-5. Second grounding line 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the five electrode units 12 in the second row group, namely, electrode units 12-6 to 12-10. Third grounding line 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the five electrode units 12 in the third row group, namely, electrode units 12-11 to 12-15. Fourth grounding line 18-4 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the four electrode units 12 in the fourth row group, namely, electrode units 12-16 to 12-19. In short, each grounding line 18 short-circuits the ground terminals 14-1 of the temperature sensors 14 of all electrode units 12 in each row group and grounds them.

[0136] The five dual-purpose signal lines 19 of the electrode sheet 10A include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-1, electrode unit 12-6, electrode unit 12-11, and electrode unit 12-16, and the signal end 14-2 of the temperature sensor 14 of each; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-2, electrode unit 12-7, electrode unit 12-12, and electrode unit 12-17, and the signal end 14-2 of the temperature sensor 14 of each; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-1, electrode unit 12-6, electrode unit 12-11, and electrode unit 12-16, and the signal end 14-2 of the temperature sensor 14 of each; The fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the four electrode units 12, namely, the electrode unit 12-3, the electrode unit 12-8, the electrode unit 12-13, and the electrode unit 12-18, and the signal end 14-2 of the temperature sensor 14; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the four electrode units 12, namely, the electrode unit 12-4, the electrode unit 12-9, the electrode unit 12-14, and the electrode unit 12-19, and the signal end 14-2 of the temperature sensor 14; one end of the fifth dual-purpose signal line 19-5 is connected to the electrode unit 12-5, the electrode unit 12

[0137] 10. Electrode Units 12-15: The dielectric elements 15 of the three electrode units 12 and the signal terminals 14-2 of the temperature sensors 14. In short, each dual-purpose signal line 19 parallel-circuits the dielectric elements 15 and the signal terminals 14-2 of the temperature sensors 14 of the electrode units 12 in the same column group and connects to the adapter 20.

[0138] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 of the adapter 20 are electrically connected to the first grounding line 18-1, the second grounding line 18-2, the third grounding line 18-3, and the fourth grounding line 18-4 of the electrode sheet 10A, respectively, via the first connector 40A. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5 of the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode sheet 10A, respectively, via the first connector 40A. The tumor electric field therapy system formed by the electrode sheet 10A, the adapter 20, and the electric field generator 30 operates in the same manner as the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are disconnected and the input terminals 2 of all bidirectional switches 26 are connected and the acquisition terminals 1 are disconnected, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 are connected to the AC signal. When the acquisition terminals 1 of all bidirectional switches 26 are connected and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group are sequentially obtained by sequentially turning on each grounding switch 25.

[0139] refer to Figure 7As shown, the electrode sheet 10B of the third embodiment is provided with 17 electrode units 12, and the flexible circuit board 11B electrically connects the 17 electrode units 12 in four rows and five columns, in which three rows each have five electrode units 12, and the remaining one row has two electrode units 12. The electrode sheet 10B includes four ground lines 18 and five dual-purpose signal lines 19. Each ground line 18 is used to ground the ground ends 14-1 of the temperature sensors 14 of the electrode units 12 in the same row group. Each dual-purpose signal line 19 is used to short the dielectric elements 15 and the signal ends 14-2 of the temperature sensors 14 of the electrode units 12 in each column group, for receiving temperature detection signals or transmitting alternating current signals. The four ground lines 18 of the electrode sheet 10B include a first ground line 18-1, a second ground line 18-2, a third ground line 18-3, and a fourth ground line 18-4. The first row group includes the electrode units 12-1 to 12-5, the second row group includes the electrode units 12-6 to 12-10, the third row group includes the electrode units 12-11 to 12-15, and the fourth row group includes the electrode units 12-16 and 12-17. Specifically, the first ground line 18-1 is used to ground the ground ends 14-1 of the temperature sensors 14 of the five electrode units 12-1 to 12-5 in the first row group. The second ground line 18-2 is used to ground the ground ends 14-1 of the temperature sensors 14 of the five electrode units 12-6 to 12-10 in the second row group. The third ground line 18-3 is used to ground the ground ends 14-1 of the temperature sensors 14 of the five electrode units 12-11 to 12-15 in the third row group. The fourth ground line 18-4 is used to ground the ground ends 14-1 of the temperature sensors 14 of the two electrode units 12-16 and 12-17 in the fourth row group. In short, each ground line 18 shorts and grounds the ground ends 14-1 of the temperature sensors 14 of all the electrode units 12 in the corresponding row group.

[0140] The five dual-purpose signal lines 19 of the electrode sheet 10B include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-1, electrode unit 12-6, electrode unit 12-11, and electrode unit 12-16, and the signal end 14-2 of the temperature sensor 14 of each; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-2, electrode unit 12-7, electrode unit 12-12, and electrode unit 12-17, and the signal end 14-2 of the temperature sensor 14 of each; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-3, electrode unit 12-6, electrode unit 12-11, and electrode unit 12-16, and the signal end 14-2 of the temperature sensor 14 of each The fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the three electrode units 12 (electrode unit 12-8 and electrode unit 12-13) and the signal terminals 14-2 of the temperature sensors 14. One end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the three electrode units 12 (electrode unit 12-4, electrode unit 12-9, and electrode unit 12-14) and the signal terminals 14-2 of the temperature sensors 14. One end of the fifth dual-purpose signal line 19-5 is connected to the dielectric elements 15 of the three electrode units 12 (electrode unit 12-5, electrode unit 12-10, and electrode unit 12-15) and the signal terminals 14-2 of the temperature sensors 14. In short, each dual-purpose signal line 19 parallel-circuits the dielectric elements 15 and the signal terminals 14-2 of the temperature sensors 14 of the electrode units 12 in the same column group and connects them to the adapter 20.

[0141] The first ground switch 25-1, the second ground switch 25-2, the third ground switch 25-3 and the fourth ground switch 25-4 of the adapter 20 are respectively electrically connected with the first ground line 18-1, the second ground line 18-2, the third ground line 18-3 and the fourth ground line 18-4 of the electrode sheet 10B through the first connector 40B. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 of the adapter 20 are respectively electrically connected with the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4 and the fifth dual-purpose signal line 19-5 of the electrode sheet 10B through the first connector 40B. The working mode of the tumor electric field treatment system formed by the electrode sheet 10B, the adapter 20 and the electric field generator 30 is the same as that of the tumor electric field treatment system 100. When all the ground switches 25 are turned off and the input end 2 of all the bidirectional switches 26 is turned on and the collection end 1 is turned off, all the dual-purpose signal lines 19 are turned on with the AC signal line 28, and all the electrode units 12 are connected with the AC signal. When the collection end 1 of all the bidirectional switches 26 is turned on and the input end 2 is turned off, the temperature detection signal of the temperature sensor 14 of each electrode unit 12 of each row group can be obtained in turn by turning on each ground switch 25 in turn.

[0142] Reference Figure 8As shown, the electrode sheet 10C of the fourth embodiment is provided with 17 electrode units 12, similar to the electrode sheet 10B of the third embodiment. However, the specific circuit connection arrangement of each electrode unit 12 is different. The flexible circuit board 11C of the electrode sheet 10C also electrically arranges these 17 electrode units 12 into four rows and five columns, except that one row has five electrode units 12, and the remaining three rows each have four electrode units 12. The electrode sheet 10C includes four grounding wires 18 and five dual-purpose signal wires 19. Each grounding wire 18 is used to ground the ground terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 and the signal terminal 14-2 of each temperature sensor 14 in each column group, respectively, for receiving temperature detection signals or transmitting AC signals. The four ground lines 18 of the electrode sheet 10C include a first ground line 18-1, a second ground line 18-2, a third ground line 18-3, and a fourth ground line 18-4. The first row group includes electrode units 12-1 through 12-5, the second row group includes electrode units 12-6 through 12-9, the third row group includes electrode units 12-10 through 12-13, and the fourth row group includes electrode units 12-14 through 12-17. Specifically, first grounding line 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the five electrode units 12 in the first row group, namely electrode units 12-1 to 12-5. Second grounding line 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the four electrode units 12 in the second row group, namely electrode units 12-6 to 12-9. Third grounding line 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the four electrode units 12 in the third row group, namely electrode units 12-10 to 12-13. Fourth grounding line 18-4 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the four electrode units 12 in the fourth row group, namely electrode units 12-14 to 12-17. In short, each grounding line 18 short-circuits the ground terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group and grounds them.

[0143] The five dual-purpose signal lines 19 of the electrode sheet 10C include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-1, electrode unit 12-6, electrode unit 12-10, and electrode unit 12-14, and the signal end 14-2 of the temperature sensor 14 of each; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-2, electrode unit 12-7, electrode unit 12-11, and electrode unit 12-15, and the signal end 14-2 of the temperature sensor 14 of each; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-3, electrode unit 12-6, electrode unit 12-10, and electrode unit 12-14, and the signal end 14-2 of the temperature sensor 14 of each The dielectric elements 15 of the four electrode units 12 (electrode unit 12-8, electrode unit 12-12, and electrode unit 12-16) and the signal terminals 14-2 of their respective temperature sensors 14 are connected. One end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric elements 15 of the four electrode units 12 (electrode unit 12-4, electrode unit 12-9, electrode unit 12-13, and electrode unit 12-17) and the signal terminals 14-2 of their respective temperature sensors 14. One end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of one electrode unit 12 (electrode unit 12-5) and the signal terminal 14-2 of its temperature sensor 14. In short, each dual-purpose signal line 19 parallel-circuits the dielectric elements 15 and the signal terminals 14-2 of their respective temperature sensors 14 of each electrode unit 12 in the same column group and is used to connect to the adapter 20.

[0144] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 of the adapter 20 are electrically connected to the first grounding line 18-1, the second grounding line 18-2, the third grounding line 18-3, and the fourth grounding line 18-4 of the electrode sheet 10C, respectively, via the first connector 40C. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5 of the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode sheet 10C, respectively, via the first connector 40C. The tumor electric field therapy system formed by the electrode sheet 10C, the adapter 20, and the electric field generator 30 operates in the same manner as the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are disconnected and the input terminals 2 of all bidirectional switches 26 are connected and the acquisition terminals 1 are disconnected, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 are connected to the AC signal. When the acquisition terminals 1 of all bidirectional switches 26 are connected and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group are sequentially obtained by sequentially turning on each grounding switch 25.

[0145] refer to Figure 9 The fifth embodiment of the present application is a tumor electric field treatment system 100D, which is Figure 1 The difference between the tumor electric field treatment system 100 described in the embodiment is that this embodiment uses the electrode sheet 10D of the fifth embodiment and Figure 1 The adapter 20 shown in the figure is electrically connected to the electric field generator 30. There are also four electrode sheets 10D in this embodiment, which are respectively connected to the first socket 42 of the adapter 20 through the first plug 41D provided at the end of each first cable 13D. Each electrode sheet 10D also includes a plurality of electrode units 12D that are both axially symmetrically arranged and centrally arranged, a plurality of connecting portions 111D located between adjacent electrode units 12, and a wiring portion 112D electrically connected to the first cable 13D; however, the wiring portion 112D is extended from an electrode unit 12 toward the outside of the electrode array (unnumbered) and is arranged perpendicular to a connecting portion 111D. The first cable 13D has 8 core conductors.

[0146] The electrode units 12D of the electrode sheet 10D have the same structure as the electrode units 12 in the aforementioned embodiment, the only difference being that the number of electrode units 12 in this embodiment is 13, and they are spatially arranged in five rows and five columns. Specifically, the first and last rows each have two electrode units 12, located in the second and fourth columns, respectively; each of the three middle rows has three electrode units 12, and the three electrode units 12 in each row are located in the first, third, and fifth columns, respectively. There are three electrode units 12 located in the center of the electrode array (unnumbered), namely, the three electrode units 12 located in the second row and third column, the third row and third column, and the third row and third column. The rest are electrode units 12 located on the periphery of the electrode array (unnumbered). Adjacent electrode units 12 in the periphery are connected by connecting portions 111D. The electrode units 12 in the second row and third column are connected to the electrode units 12 in the first and second rows and adjacent thereto via connecting portions 111D. The electrode units 12 in the fourth row and third column are connected to the electrode units 12 in the fourth and fifth rows and adjacent thereto via connecting portions 111D. The electrode units 12 in the third row and third column are also connected to the electrode units 12 adjacent thereto in the row and column directions via connecting portions 111D. The electrode units 12 in the periphery are connected in pairs via connecting portions 111D to form an octagonal ring structure.

[0147] Figure 10 For use Figure 9 The electrode sheet 10D of the fifth embodiment of the tumor electric field treatment system 100D is shown as follows: Figure 1 , which is a schematic diagram of the circuit connection of the adapter 20 of the first embodiment. The following describes the circuit by taking the electrode sheet 10D in the fifth embodiment as an example. In terms of electrical connection, the flexible circuit board 11D of the electrode sheet 10D arranges the 13 electrode units 12 into three rows and three columns, wherein two rows each have five electrode units 12, and the remaining row has three electrode units 12. The electrode sheet 10D includes three grounding wires 18 and five dual-purpose signal wires 19, each of which is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group, and each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, respectively, for receiving temperature detection signals or transmitting AC signals.

[0148] The three grounding wires 18 of the electrode sheet 10D are respectively a first grounding wire 18-1, a second grounding wire 18-2, and a third grounding wire 18-3. Of the three row groups of the electrode sheet 10D, the first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-10, and the third row group includes electrode units 12-11 to 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-5 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of the electrode units 12-6 to 12-10 in the second row group; and the third grounding wire 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of the electrode units 12-11 to 12-13 in the third row group. In short, each ground line 18 short-circuits the ground terminals 14 - 1 of the temperature sensors 14 of all the electrode units 12 in the corresponding row group and connects them to ground.

[0149] The five dual-purpose signal lines 19 of the electrode sheet 10D include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric elements 15 of the three electrode units 12, namely, the electrode unit 12-1, the electrode unit 12-6, and the electrode unit 12-11, and the signal end 14-2 of the temperature sensor 14 of each; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric elements 15 of the three electrode units 12, namely, the electrode unit 12-2, the electrode unit 12-7, and the electrode unit 12-12, and the signal end 14-2 of the temperature sensor 14 of each; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the electrode unit 12-3, the electrode unit 12-6, and the electrode unit 12-11, and the signal end 14-2 of the temperature sensor 14 of each The fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the three electrode units 12 (electrode units 12-8 and 12-13) and the signal terminals 14-2 of their respective temperature sensors 14. One end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the two electrode units 12 (electrode units 12-4 and 12-9) and the signal terminals 14-2 of their respective temperature sensors 14. One end of the fifth dual-purpose signal line 19-5 is connected to the dielectric elements 15 of the two electrode units 12 (electrode units 12-5 and 12-10) and the signal terminals 14-2 of their respective temperature sensors 14. In short, each dual-purpose signal line 19 parallel-circuits the dielectric elements 15 and the signal terminals 14-2 of their respective temperature sensors 14 of the electrode units 12 in the same column group and is used to connect to the adapter 20.

[0150] The first ground switch 25-1, the second ground switch 25-2 and the third ground switch 25-3 of the adapter 20 are respectively electrically connected with the first ground line 18-1, the second ground line 18-2 and the third ground line 18-3 of the electrode sheet 10D through the first connector 40D, and the fourth ground switch 25-4 is in the idle open state. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 of the adapter 20 are respectively electrically connected with the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4 and the fifth dual-purpose signal line 19-5 of the electrode sheet 10D through the first connector 40D.

[0151] The working mode of the tumor electric field treatment system formed by the electrode sheet 10D, the adapter 20 and the electric field generator 30 is the same as that of the tumor electric field treatment system 100. When all the ground switches 25 are open and the input end 2 of all the bidirectional switches 26 is on and the collection end 1 is open, all the dual-purpose signal lines 19 are connected with the AC signal line 28, and all the electrode units 12 are connected with the AC signal. When the collection end 1 of all the bidirectional switches 26 is on and the input end 2 is open, the temperature detection signal of the temperature sensor 14 of each electrode unit 12 of each row group can be obtained by sequentially turning on each ground switch 25. The ground switch 25-4 in the idle open state does not need to be operated.

[0152] Figure 11 The electrode sheet 10D of the fifth embodiment shown in FIG. 5 is the same as the electrode sheet 10 shown in FIG. 1. Figure 9 The electrode sheet 10D of the fifth embodiment shown in FIG. 5 is the same as the electrode sheet 10 shown in FIG. 1. Figure 1, another circuit connection diagram of the adapter 20 of the first embodiment is shown in FIG. The flexible circuit board 11E of the electrode sheet 10E in this embodiment also electrically arranges the 13 electrode units 12 into three rows and five columns, except that two rows each have four electrode units 12, and the remaining row has five electrode units 12. The electrode sheet 10E also includes three grounding wires 18 and five dual-purpose signal wires 19. Each grounding wire 18 is used to ground the ground terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 and the signal terminal 14-2 of each temperature sensor 14 in the same column group, respectively, for receiving temperature detection signals or transmitting AC signals. The three grounding wires 18 of the electrode sheet 10E include a first grounding wire 18-1, a second grounding wire 18-2, and a third grounding wire 18-3. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, and the third row group includes electrode units 12-9 to 12-13. Specifically, first grounding line 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of electrode units 12-1 to 12-4 in the first row group; second grounding line 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of electrode units 12-5 to 12-8 in the second row group; and third grounding line 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of electrode units 12-9 to 12-13 in the third row group. In short, each grounding line 18 short-circuits the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group and grounds them.

[0153] The 5-way dual-purpose signal lines 19 of the electrode sheet 10E include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-1, 12-5, and 12-9, respectively and simultaneously. One end of the second dual-purpose signal line 19-2 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-2, 12-6, and 12-10, respectively and simultaneously. One end of the third dual-purpose signal line 19-3 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-3, 12-7, and 12-11, respectively and simultaneously. One end of the fourth dual-purpose signal line 19-4 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-4, 12-8, and 12-12, respectively and simultaneously. One end of the fifth dual-purpose signal line 19-5 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of the electrode unit 12-13. In short, each of the dual-purpose signal lines 19 connects the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the electrode units 12 in the same column group in parallel and is used to connect to the adapter 20.

[0154] The first ground switch 25-1, the second ground switch 25-2, and the third ground switch 25-3 of the adapter 20 are respectively and correspondingly connected to the first ground line 18-1, the second ground line 18-2, and the third ground line 18-3 of the electrode sheet 10E through the first connector 40E, and the fourth ground switch 25-4 is in an idle and disconnected state. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5 of the adapter 20 are respectively and correspondingly connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode sheet 10E through the first connector 40E.

[0155] The tumor therapy field system formed by the electrode sheet 10E, adapter 20, and electric field generator 30 operates in the same manner as the aforementioned tumor therapy field system 100. When all grounding switches 25 are disconnected and the input terminals 2 of all bidirectional switches 26 are connected and the acquisition terminal 1 is disconnected, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 receive AC signals. When the acquisition terminals 1 of all bidirectional switches 26 are connected and the input terminals 2 are disconnected, the temperature detection signals from the temperature sensors 14 of each electrode unit 12 in each row group are sequentially connected by turning on each grounding switch 25. No operation is required for grounding switches 25 that are in an idle and disconnected state.

[0156] Figure 12 and Figure 11 Similarly, it is also used for Figure 9 The electrode sheet 10D shown in FIG. Figure 1 Another circuit connection diagram of the adapter 20 shown in FIG. Figure 12As shown, an electrode sheet 10F of the tumor therapy field system of the seventh embodiment has 13 electrode units 12, similar to the electrode sheet 10D of the tumor therapy field system of the fifth embodiment. However, the specific circuit layout differs. The flexible circuit board 11F of the electrode sheet 10F electrically arranges these 13 electrode units 12 into four rows and four columns, with three rows each having four electrode units 12, and the remaining row having one electrode unit 12. The electrode sheet 10F includes four grounding wires 18 and four dual-purpose signal wires 19. Each grounding wire 18 is used to ground the ground terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 in a corresponding column group and the signal terminal 14-2 of each temperature sensor 14, respectively, for receiving temperature detection signals or transmitting AC signals. The four grounding lines 18 of the electrode sheet 10F include a first grounding line 18-1, a second grounding line 18-2, a third grounding line 18-3 and a fourth grounding line 18-4. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, the third row group includes electrode units 12-9 to 12-12, and the fourth row group includes electrode unit 12-13. Specifically, first grounding line 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of electrode units 12-1 through 12-4 in the first row group; second grounding line 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of electrode units 12-5 through 12-8 in the second row group; third grounding line 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of electrode units 12-9 through 12-12 in the third row group; and fourth grounding line 18-4 is used to ground the ground terminal 14-1 of the temperature sensor 14 of electrode unit 12-13 in the fourth row group. In short, each grounding line 18 short-circuits the ground terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group and grounds them.

[0157] The four dual-purpose signal lines 19 of the electrode sheet 10F include a first dual-purpose signal line 19 - 1 , a second dual-purpose signal line 19 - 2 , a third dual-purpose signal line 19 - 3 , and a fourth dual-purpose signal line 19 - 4 . One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the four electrode units 12, namely, electrode unit 12-1, electrode unit 12-5, electrode unit 12-9, and electrode unit 12-13, and the signal end 14-2 of the temperature sensor 14 of each; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the three electrode units 12, namely, electrode unit 12-2, electrode unit 12-6, and electrode unit 12-10, and the signal end 14-2 of the temperature sensor 14 of each; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the three electrode units 12, namely, electrode unit 12-3, electrode unit 12-7, and electrode unit 12-11, and the signal end 14-2 of the temperature sensor 14 of each; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the three electrode units 12, namely, electrode unit 12-4, electrode unit 12-8, and electrode unit 12-12, and the signal end 14-2 of the temperature sensor 14 of each. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 and the signal terminals 14 - 2 of the temperature sensors 14 of the electrode units 12 in the same column group in parallel and is used to connect to the adapter 20 .

[0158] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 of the adapter 20 are electrically connected to the first grounding line 18-1, the second grounding line 18-2, the third grounding line 18-3, and the fourth grounding line 18-4 of the electrode sheet 10F, respectively, via the first connector 40F. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, and the fourth bidirectional switch 26-4 of the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, and the fourth dual-purpose signal line 19-4, respectively, via the first connector 40F. The fifth bidirectional switch 26-5 is in an idle and disconnected state.

[0159] The tumor therapy field system formed by the electrode sheet 10F, adapter 20, and electric field generator 30 operates in the same manner as the aforementioned tumor therapy field system 100. When all grounding switches 25 are disconnected and the input terminals 2 of all bidirectional switches 26 are connected and the acquisition terminals 1 are disconnected, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 receive AC signals. When the acquisition terminals 1 of all bidirectional switches 26 are connected and the input terminals 2 are disconnected, the temperature detection signals from the temperature sensors 14 of each electrode unit 12 in each row group are sequentially connected by sequentially turning on each grounding switch 25. No operation is required for bidirectional switches 26 that are in an idle and disconnected state.

[0160] Figure 13 and Figure 12 Similarly, it is also used for Figure 9 The electrode sheet 10D shown in FIG. Figure 1 Another circuit connection diagram of the adapter 20 shown in FIG. Figure 13As shown, the electrode sheet 10G of the tumor electric field therapy system of the eighth embodiment also has 13 electrode units 12, but the specific circuit layout is different. The flexible circuit board 11G of the electrode sheet 10G electrically arranges these 13 electrode units 12 into four rows and four columns. Three rows each have three electrode units 12, and the remaining row has four electrode units 12. The electrode sheet 10G includes four grounding wires 18 and four dual-purpose signal wires 19. Each grounding wire 18 is used to ground the ground terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 in a corresponding column group and the signal terminal 14-2 of each temperature sensor 14, respectively, for receiving temperature detection signals or transmitting AC signals. The four grounding lines 18 of the electrode sheet 10G include a first grounding line 18-1, a second grounding line 18-2, a third grounding line 18-3 and a fourth grounding line 18-4. The first row group includes electrode units 12-1 to 12-3, the second row group includes electrode units 12-4 to 12-6, the third row group includes electrode units 12-7 to 12-9, and the fourth row group includes electrode units 12-10 to 12-13. Specifically, first grounding line 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of electrode units 12-1 through 12-3 in the first row group; second grounding line 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of electrode units 12-4 through 12-6 in the second row group; third grounding line 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of electrode units 12-7 through 12-9 in the third row group; and fourth grounding line 18-4 is used to ground the ground terminals 14-1 of the temperature sensors 14 of electrode units 12-10 through 12-13 in the fourth row group. In short, each grounding line 18 short-circuits the ground terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group and grounds them.

[0161] The 4-way dual-purpose signal lines 19 of the electrode sheet 10G include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of each of the four electrode units 12-1, 12-4, 12-7, and 12-10; one end of the second dual-purpose signal line 19-2 is connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of each of the four electrode units 12-2, 12-5, 12-8, and 12-11; one end of the third dual-purpose signal line 19-3 is connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of each of the four electrode units 12-3, 12-6, 12-9, and 12-12; and one end of the fourth dual-purpose signal line 19-4 is connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of the electrode unit 12-13. In short, each of the dual-purpose signal lines 19 connects the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of each of the electrode units 12 in the same column group in parallel and is used to connect to the adapter 20.

[0162] The first ground switch 25-1, the second ground switch 25-2, the third ground switch 25-3, and the fourth ground switch 25-4 of the adapter 20 are respectively and correspondingly connected to the first ground line 18-1, the second ground line 18-2, the third ground line 18-3, and the fourth ground line 18-4 of the electrode sheet 10G through the first connector 40G. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, and the fourth bidirectional switch 26-4 of the adapter 20 are respectively and correspondingly connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, and the fourth dual-purpose signal line 19-4 through the first connector 40G, and the fifth bidirectional switch 26-5 is in an idle and disconnected state.

[0163] The tumor therapy field system formed by the electrode sheet 10G, adapter 20, and electric field generator 30 operates in the same manner as the aforementioned tumor therapy field system 100. When all grounding switches 25 are disconnected and the input terminals 2 of all bidirectional switches 26 are connected and the acquisition terminals 1 are disconnected, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 receive AC signals. When the acquisition terminals 1 of all bidirectional switches 26 are connected and the input terminals 2 are disconnected, the temperature detection signals from the temperature sensors 14 of each electrode unit 12 in each row group are sequentially connected by turning on each grounding switch 25. No operation is performed on bidirectional switches 26 that are in an idle and disconnected state.

[0164] refer to Figure 14 and Figure 15 As shown, the primary difference between the tumor therapy field system 100H of this embodiment and the tumor therapy field system 100 is that the electrode sheet 10H of the ninth embodiment is equipped with nine electrode units 12. Spatially, these nine electrode units 12 are arranged in an array of three rows and three columns. Electrically, the flexible printed circuit board 11H of the electrode sheet 10H arranges these nine electrode units 12 into two rows and five columns, with one row having five electrode units 12 and the other row having four electrode units 12. The electrode sheet 10H includes two grounding wires 18 and five dual-purpose signal wires 19. Each grounding wire 18 connects the ground terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group to ground. Each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 and the signal terminal 14-2 of each temperature sensor 14 in each column group, respectively, for receiving temperature detection signals or transmitting AC signals. The two grounding wires 18 of the electrode sheet 10H are respectively a first grounding wire 18-1 and a second grounding wire 18-2. In the two row groups of the electrode sheet 10H, the first row group includes electrode units 12-1 to 12-5, and the second row group includes electrode units 12-6 to 12-9. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-5 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of the electrode units 12-6 to 12-9 in the second row group. In short, each grounding wire 18 short-circuits the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group and grounds them.

[0165] The five dual-purpose signal lines 19 of the electrode sheet 10H include a first dual-purpose signal line 19 - 1 , a second dual-purpose signal line 19 - 2 , a third dual-purpose signal line 19 - 3 , a fourth dual-purpose signal line 19 - 4 , and a fifth dual-purpose signal line 19 - 5 . One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 of the two electrode units 12, electrode unit 12-1 and electrode unit 12-6, and the signal end 14-2 of the temperature sensor 14 of each; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 of the two electrode units 12, electrode unit 12-2 and electrode unit 12-7, and the signal end 14-2 of the temperature sensor 14 of each; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 of the two electrode units 12, electrode unit 12-3 and electrode unit 12-8, and the signal end 14-2 of the temperature sensor 14 of each; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of the two electrode units 12, electrode unit 12-4 and electrode unit 12-9, and the signal end 14-2 of the temperature sensor 14 of each; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of electrode unit 12-5 and the signal end 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 and the signal terminals 14 - 2 of the temperature sensors 14 of the electrode units 12 in the same column group in parallel and is used to connect to the adapter 20 .

[0166] The first grounding switch 25-1 and the second grounding switch 25-2 on the adapter 20 are electrically connected to the first grounding line 18-1 and the second grounding line 18-2 of the electrode sheet 10H, respectively, via the first connector 40. The third grounding switch 25-3 and the fourth grounding switch 25-4 are in an idle and disconnected state. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5 on the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5, respectively, via the first connector 40.

[0167] The tumor therapy field system formed by the electrode sheet 10H, adapter 20, and electric field generator 30 operates in the same manner as the aforementioned tumor therapy field system 100. When all grounding switches 25 are disconnected and the input terminals 2 of all bidirectional switches 26 are connected and the acquisition terminal 1 is disconnected, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 receive AC signals. When the acquisition terminals 1 of all bidirectional switches 26 are connected and the input terminals 2 are disconnected, the temperature detection signals from the temperature sensors 14 of each electrode unit 12 in each row group are sequentially connected by turning on each grounding switch 25. No operation is required for grounding switches 25 that are in an idle and disconnected state.

[0168] refer to Figure 16 As shown, the electrode sheet 10J of the tenth embodiment is provided with nine electrode units 12. Electrically, the flexible circuit board 11J of the electrode sheet 10J arranges these nine electrode units 12 into three rows and three columns, with each row having three electrode units 12. The electrode sheet 10J includes three grounding wires 18 and three dual-purpose signal wires 19. Each grounding wire 18 is used to ground the ground terminal 14-1 of each temperature sensor 14 in a corresponding row group of electrode units 12. Each dual-purpose signal wire 19 short-circuits the dielectric element 15 of each electrode unit 12 and the signal terminal 14-2 of each temperature sensor 14 in a corresponding column group, thereby receiving temperature detection signals or transmitting AC signals. The three grounding wires 18 of the electrode sheet 10J are a first grounding wire 18-1, a second grounding wire 18-2, and a third grounding wire 18-3. Of the three row groups of electrode sheet 10J, the first row group includes electrode units 12-1 through 12-3, the second row group includes electrode units 12-4 through 12-6, and the third row group includes electrode units 12-7 through 12-9. Specifically, first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of electrode units 12-1 through 12-3 in the first row group; second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of electrode units 12-4 through 12-6 in the second row group; and third grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of electrode units 12-7 through 12-9 in the third row group. In short, each grounding wire 18 short-circuits the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group and grounds them.

[0169] The three dual-purpose signal lines 19 of the electrode sheet 10J include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, and a third dual-purpose signal line 19-3. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric elements 15 of the three electrode units 12 (electrode unit 12-1, electrode unit 12-4, and electrode unit 12-7) and the signal end 14-2 of the temperature sensor 14 of each of the three electrode units 12. One end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric elements 15 of the three electrode units 12 (electrode unit 12-2, electrode unit 12-5, and electrode unit 12-8) and the signal end 14-2 of the temperature sensor 14 of each of the three electrode units 12. One end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric elements 15 of the three electrode units 12 (electrode unit 12-3, electrode unit 12-6, and electrode unit 12-9) and the signal end 14-2 of the temperature sensor 14 of each of the three electrode units 12. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 and the signal terminals 14 - 2 of the temperature sensors 14 of the electrode units 12 in the same column group in parallel and is used to connect to the adapter 20 .

[0170] The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 of the adapter 20 are electrically connected to the first ground line 18-1, the second ground line 18-2, and the third ground line 18-3, respectively, via the first connector 40J. The fourth grounding switch 25-4 is in an idle and disconnected state. The first bidirectional switch 26-1, the second bidirectional switch 26-2, and the third bidirectional switch 26-3 of the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, and the third dual-purpose signal line 19-3, respectively, via the first connector 40J. The fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 are both in an idle and disconnected state.

[0171] The tumor therapy field system formed by the electrode sheet 10J, adapter 20, and electric field generator 30 operates in the same manner as the aforementioned tumor therapy field system 100. When all grounding switches 25 are disconnected and the input terminals 2 of all bidirectional switches 26 are connected and the acquisition terminals 1 are disconnected, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 receive AC signals. When the acquisition terminals 1 of all bidirectional switches 26 are connected and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group are sequentially connected by turning on each grounding switch 25. No operation is required for grounding switches 25 and bidirectional switches 26 that are in an idle and disconnected state.

[0172] In the tumor electric field therapy system of the present application, the flexible circuit boards (11, 11A, 11B, 11C, 11D, 11E, 11F, 11G, 11H, 11J) of the electrode sheets (10, 10A, 10B, 10C, 10D, 10E, 10F, 10G, 10H, 10J) are electrically connected to divide the electrode units 12 into multiple rows and columns, and the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12 in the same row are electrically connected to the same ground wire 18, and the electrode units in the same column are electrically connected to the same ground wire 18. The dielectric elements 15 of each element 12 and the signal terminals 14-2 of each temperature sensor 14 are short-circuited and electrically connected to the same dual-purpose signal line 19; the adapter 20 is provided with a plurality of grounding switches 25 and a plurality of bidirectional switching switches 26; the grounding lines 18 of each electrode sheet (10, 10A, 10B, 10C, 10D, 10E, 10F, 10G, 10H, 10J) are electrically connected one by one to the corresponding grounding switches 25, and the dual-purpose signal lines 19 are electrically connected one by one to the corresponding bidirectional switching switches 26. Among them, the number of grounding switches 25 is greater than or equal to the number of grounding wires 18, and the number of bidirectional switching switches 26 is greater than or equal to the number of dual-purpose signal lines 19. Therefore, the adapter 20 can adapt to a variety of electrode sheets (10, 10A, 10B, 10C, 10D, 10E, 10F, 10G, 10H, 10J), which has a grounding switch 25 in an idle disconnected state and / or a bidirectional switching switch 26 in an idle disconnected state.

[0173] The present application also provides some temperature detection methods and AC signal application control methods, which are described below using the electrode sheet 10 as an example.

[0174] The present application embodiment provides an electrode sheet temperature detection method, which is applied to the above-mentioned electrode sheet 10 or tumor electric field treatment system 100. Figure 17 As shown, it includes the following steps:

[0175] Step 210: Control each bidirectional switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to disconnect the AC signal applied to the dielectric element 15 of each electrode unit 12 of the electrode sheet 10 and simultaneously connect the DC signal applied to the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10;

[0176] Step 220 : Turn on the grounding switches 25 electrically connected to the grounding terminals 14 - 1 of the temperature sensors 14 of the electrode units 12 of the electrode sheet 10 in sequence to obtain temperature detection signals from the temperature sensors 14 of the electrode units 12 of the electrode sheet 10 .

[0177] Step 210 is specifically as follows: controlling the bidirectional switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to switch from the end electrically connected to the AC signal to the end electrically connected to the DC signal, that is, controlling the bidirectional switch 26 electrically connected to the electrode sheet 10 to switch from its input end 2 to its collection end 1; or

[0178] The bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 is controlled to switch the dielectric element 15 of each electrode unit 12 of the electrode sheet 10 from the on state to the off state, and at the same time, the signal end 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10 is switched from the off state to the on state.

[0179] The electrode sheet temperature detection method of the present application can quickly and accurately obtain the temperature of all electrode units of the electrode sheet; and based on the obtained temperature detection signals of all temperature sensors of the electrode sheet, it can be judged whether the temperature sensors of the electrode sheet are faulty, whether there is an abnormality, whether the electrode sheet is qualified, and whether it needs to be replaced; it can also be judged whether each electrode unit of the electrode sheet is overheated based on the obtained temperature detection signals of all temperature sensors of the electrode sheet when each temperature sensor of the electrode sheet is normal, and then control the AC signal applied to the electrode sheet or applied to each electrode unit of the electrode sheet; it can also be used to identify the type of electrode sheet when there is no abnormality in the temperature detection signals of each temperature sensor of the electrode sheet.

[0180] Ginseng Figure 18 As shown, the embodiment of the present application further provides a method for controlling application of an AC signal for tumor electric field therapy, which includes the above steps 210 and 220, and after step 220, further includes:

[0181] Step 260 : When it is determined that the electrode sheet 10 does not need to be replaced, the AC signal applied to each electrode unit 12 of the electrode sheet 10 is controlled or adjusted according to the temperature detection signal of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10 .

[0182] Controlling or adjusting the AC signal applied to each electrode unit 12 of the electrode sheet 10 in step 260 also includes:

[0183] Step 261: When the temperature detection signals of the electrode units 12 of the electrode sheet 10 obtained do not exceed the preset temperature threshold, continue to apply the AC signal to the electrode units 12 of the electrode sheet 10; or

[0184] Step 262 : When a temperature detection signal among the acquired temperature detection signals of all the electrode units 12 of the electrode sheet 10 exceeds a preset temperature threshold, stop applying the AC signal to the electrode units 12 of the electrode sheet 10 .

[0185] The stopping of applying the AC signal to the electrode unit 12 of the electrode sheet 10 described in step 262 includes stopping applying the AC signal to all electrode units 12 of the electrode sheet 10, stopping applying the AC signal to the electrode unit 12 in the electrode sheet 10 whose temperature detection signal exceeds the preset temperature threshold, and stopping applying the AC signal to all electrode units 12 in the column where the electrode unit 12 in the electrode sheet 10 whose temperature detection signal exceeds the preset temperature threshold is located.

[0186] When the application of the AC signal to the electrode unit 12 in the electrode sheet 10 whose temperature detection signal exceeds the preset temperature threshold is stopped, the AC signal continues to be applied to the electrode unit 12 in the electrode sheet 10 whose temperature detection signal does not exceed the preset temperature threshold.

[0187] When the application of the AC signal to all electrode units 12 in the column where the electrode unit 12 whose temperature detection signal exceeds the preset temperature threshold in the electrode sheet 10 is located is stopped, the AC signal continues to be applied to all electrode units 12 in the electrode sheet 10 where the temperature detection signal does not exceed the preset temperature threshold and is in a different column from the electrode unit 12 whose temperature detection signal exceeds the preset temperature threshold.

[0188] The process of continuing to apply the AC signal to the electrode sheet 10 in step 261 is specifically as follows:

[0189] Step 263: When the temperature detection signal is much lower than the preset temperature threshold, continue to apply the AC signal to each electrode unit 12 of the electrode sheet 10 in a manner of increasing the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10 or continue to apply the AC signal to each electrode unit 12 of the electrode sheet 10 in a manner of keeping the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10 unchanged; or

[0190] Step 264: When the temperature detection signal approaches a preset temperature threshold, continue to apply the AC signal to each electrode unit 12 of the electrode sheet 10 in a manner that keeps the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10 unchanged, or continue to apply the AC signal to each electrode unit 12 of the electrode sheet 10 in a manner that reduces the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10.

[0191] Ginseng Figure 19 As shown, the present application also provides a signal control method for tumor electric field therapy, which is used for the above-mentioned electrode sheet 10, and the method includes:

[0192] Step 310: Combine and control the grounding switch 25 and the bidirectional switch 26 electrically connected to the corresponding electrode sheet 10 to apply an AC signal to each electrode unit 12 of the electrode sheet 10 and execute step 320;

[0193] Step 320: Combine and control the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to collect temperature detection signals of each electrode unit of the electrode sheet 10 in a row and execute step 330;

[0194] Step 330: Determine the combined control mode of the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 according to the collected temperature detection signal and execute step 340;

[0195] Step 340 : Control the working state of each electrode unit 12 of the electrode sheet 10 according to the determined combined control mode of the grounding switch 25 and the bidirectional switch 26 .

[0196] The operating states of the electrode units 12 of the electrode sheet 10 described in step 340 include: stopping applying the AC signal and continuing to collect the temperature detection signal, and stopping collecting the temperature detection signal and continuing to apply the AC signal. Continuing to apply the AC signal includes continuing to apply the AC signal in a manner of increasing the voltage or current amplitude of the currently applied AC signal, continuing to apply the AC signal in a manner of maintaining the voltage or current amplitude of the currently applied AC signal, and continuing to apply the AC signal in a manner of decreasing the voltage or current amplitude of the currently applied AC signal.

[0197] The operating state of each electrode unit 12 of the electrode sheet 10 is determined by the temperature detection signal collected by the electrode unit 12. The electrode units 12 of the electrode sheet 10 are divided into different areas. The combination of the grounding switch 25 and the bidirectional switch 26 controls each electrode unit 12 in each area to cyclically switch between applying an AC signal and collecting a temperature detection signal.

[0198] This embodiment of the present application provides another electrode temperature detection method for the tumor electric field therapy system 100, please refer to Figure 20 As shown, the temperature detection method includes:

[0199] Step 510: disconnect the AC signal input to the electrode sheet 10, perform combination control on the multiple grounding switches 25 and the multiple bidirectional switches 26, and obtain the temperature detection signal of the temperature sensor 14 of the electrode sheet 10 corresponding to each combination in all combinations;

[0200] Step 520: sampling and converting the temperature detection signal detected by each temperature sensor 14 in the electrode sheet 10 to obtain a digital temperature signal;

[0201] Step 530: Transmit the digital temperature signal to the electric field generator 30 of the tumor electric field therapy system 100, so that the electric field generator 30 determines the temperature at the corresponding electrode unit 12 according to the digital temperature signal.

[0202] In step 510, the "combined control of the plurality of grounding switches 25 and the plurality of bidirectional switching switches 26" specifically includes:

[0203] Step 511: All bidirectional switching switches 26 are placed in the collection end 1 to turn on the electrical connection between the signal end 14-2 of each temperature sensor 14 of all electrode units 12 and the corresponding analog-to-digital converter 23.

[0204] Step 512: One of the plurality of grounding switches 25 is closed in turn and separately in time to collect the temperature detection signals detected by the temperature sensors 14 of each electrode unit 12 in the corresponding row group in turn.

[0205] The step 512 of closing one of the plurality of grounding switches 25 in turn and separately in time can make the detection channel of the analog-to-digital converter 23 and each temperature sensor 14 in the corresponding row group of the closed grounding switch 25 electrically connected.

[0206] Thus, the temperature detection signals of each temperature sensor 14 in each row group can be obtained in turn, and the corresponding temperature of all electrode units 12 on the electrode sheet 10 can be obtained after processing by the adapter 20 or the electric field generator 30; thereby making the temperature detection of the patient's body surface more comprehensive and accurate.

[0207] The tumor electric field treatment system 100 according to the embodiment of the present application can also detect the temperature of a single electrode unit 12 as needed. The specific process of detecting the temperature of a certain electrode unit 12 of the electrode sheet 10 is as follows: disconnect the input of the alternating current signal, place the bidirectional switching switch 26 corresponding to the column group in which the electrode unit 12 to be individually temperature detected in the collection end 1, place the remaining bidirectional switching switches 26 in the input end 2; at the same time, turn on and ground the grounding switch 25 corresponding to the row group in which the electrode unit 12 to be individually temperature detected, and disconnect all the remaining grounding switches 25. Thus, the temperature detection signal of the temperature sensor 14 in the electrode unit 12 to be individually temperature detected can be sampled to obtain the temperature of the electrode unit 12. For example, the electrode unit 12 to be individually temperature detected is the electrode unit 12-1, at this time, the corresponding AC signal switch 35 of the electric field generator 30 is disconnected, the first bidirectional switching switch 26-1 corresponding to the electrode unit 12-1 is placed in the collection end 1, and the remaining bidirectional switching switches (the second bidirectional switching switch 26-2, the second bidirectional switching switch 26-3, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4) are all placed in the input end 2; at the same time, the first grounding switch 25-1 corresponding to the electrode unit 12-1 is closed and grounded, and the remaining grounding switches (the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4) are all disconnected. Thus, the temperature of the electrode unit 12-1 can be detected.

[0208] The present application also provides another method for applying an AC signal for tumor electric field therapy, which is applied to the above-mentioned tumor electric field therapy system 100. Figure 21 As shown, the AC signal applying method includes:

[0209] Step 610: Determine the area of ​​the electrode unit 12 in the electrode sheet 10 where the alternating current signal needs to be applied;

[0210] Step 611: Combining and controlling the plurality of grounding switches 25 and the plurality of bidirectional switches 26 electrically connected to the electrode sheet 10 to apply an alternating current signal.

[0211] In step 611, “combining and controlling the plurality of grounding switches 25 and the plurality of bidirectional switches 26 electrically connected to the electrode sheet 10” is specifically as follows:

[0212] Step 612: Disconnect all grounding switches 25 electrically connected to the electrode sheet 10;

[0213] Step 613: determining the column group where the electrode units 12 to which the AC signal needs to be applied are located according to the area where the electrode units 12 to which the AC signal needs to be applied are located;

[0214] Step 614: Determine the bidirectional switches 26 electrically connected to the electrode units 12 in the column groups according to the column groups where the electrode units 12 to which the AC signals need to be applied are located;

[0215] In step 610 , every four adjacent electrode units 12 in the electrode sheet 10 are divided into a region. The four electrode units 12 in each region correspond to a column group and are connected to a dual-purpose signal line 19 corresponding to the same bidirectional switch 26 .

[0216] Step 615: Control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which an AC signal needs to be applied so that the electrode unit 12 to which an AC signal needs to be applied is electrically connected to the AC signal line 28 to apply the AC signal; at the same time, control the remaining bidirectional switching switches 26 so that the electrical connection between each electrode unit 12 in the area where no AC signal needs to be applied and the AC signal line 28 is disconnected to stop applying the AC signal.

[0217] In step 615, "electrically connecting the electrode units to which an AC signal needs to be applied to the AC signal line 28 to apply the AC signal and disconnecting the electrical connection between the electrode units 12 in the area where the AC signal does not need to be applied and the AC signal line 28 to stop applying the AC signal" is achieved by placing the bidirectional switching switch 26 electrically connected to the electrode units 12 in the column group corresponding to the area to which the AC signal is to be applied in the electrode sheet 10 at its input end 2, and placing all the bidirectional switching switches 26 electrically connected to the electrode units 12 in the remaining column groups at the collection end 1.

[0218] The first controller 22 in the adapter 20 or the electric field generator 30 of the tumor electric field treatment system 100 in the embodiments of the present application is provided with a preset number threshold, a first preset temperature t1, a second preset temperature t2, and a preset temperature threshold t0, wherein the first preset temperature t1 is lower than the second preset temperature t2, and the second preset temperature t2 is lower than the preset temperature threshold t0.

[0219] The embodiments of the present application also provide an alternating current signal application method based on a temperature detection signal, which is used for the tumor electric field treatment system 100. Figure 22 As shown in the figure, the application method comprises the following steps:

[0220] Step 710: starting the tumor electric field treatment system 100;

[0221] Step 711: combining control of the grounding switch 25 and the bidirectional switch 26 electrically connected with the electrode sheet 10 to apply an alternating current signal to each electrode unit 12 of the electrode sheet 10;

[0222] Step 712: combining control of the grounding switch 25 and the bidirectional switch 26 electrically connected with the electrode sheet 10 to obtain the temperature of each electrode unit 12 of the electrode sheet 10;

[0223] Step 713: judging whether there is an electrode unit 12 with a temperature exceeding the first preset temperature t1, and when there is no electrode unit 12 with a temperature exceeding the first preset temperature t1, executing step 714, and when there is an electrode unit 12 with a temperature exceeding the first preset temperature t1, executing step 715;

[0224] Step 714: continuing to apply the alternating current signal to each electrode unit 12 of the electrode sheet 10 in a manner of increasing the voltage or current amplitude of the currently applied alternating current signal and returning to step 712;

[0225] Step 715: judging whether there is an electrode unit 12 with a temperature exceeding the second preset temperature t2, and when there is no electrode unit 12 with a temperature exceeding the second preset temperature t2, executing step 716, and when there is an electrode unit 12 with a temperature exceeding the second preset temperature t2, executing step 717;

[0226] Step 716: continuing to apply the alternating current signal to each electrode unit 12 of the electrode sheet 10 in a manner of keeping the voltage or current amplitude of the currently applied alternating current signal unchanged and returning to step 712;

[0227] Step 717: judging whether there is an electrode unit 12 with a temperature exceeding the preset temperature threshold t0, and when there is no electrode unit 12 with a temperature exceeding the preset temperature threshold t0, executing step 718, and when there is an electrode unit with a temperature exceeding the preset temperature threshold t0, executing step 719;

[0228] Step 718: Continue applying the AC signal to all electrode units 12 of the electrode sheet 10 in a manner of reducing the voltage or current amplitude of the currently applied AC signal and return to step 712;

[0229] Step 719: Determine the number of over-temperature regions and execute step 720, wherein the over-temperature region is a region containing electrode units whose temperatures exceed the preset temperature threshold t0, and the non-over-temperature region is a region in which the temperatures of all electrode units do not exceed the preset temperature threshold t0;

[0230] Step 720: Determine whether the number of over-temperature areas exceeds a preset number threshold. If the number of over-temperature areas exceeds the preset number threshold, execute step 721. If the number of over-temperature areas does not exceed the preset number threshold, execute step 724.

[0231] Step 721: Stop applying the AC signal to each electrode unit 12 of the electrode sheet 10 and execute step 722;

[0232] Step 722: Combine and control the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to obtain the temperature of each electrode unit 12 of the electrode sheet 10 and execute step 723;

[0233] Step 723: Determine whether there is an electrode unit 12 with a temperature exceeding the first preset temperature t1. If no electrode unit 12 with a temperature exceeding the first preset temperature t1 exists in the electrode sheet 10, the process returns to step 711. If no electrode unit 12 with a temperature exceeding the first preset temperature t1 exists in the electrode sheet 10, the process returns to step 722.

[0234] Step 724: Distinguish between an over-temperature area and a non-over-temperature area based on whether the area contains an electrode unit 12 whose temperature exceeds the preset temperature threshold t0. If the area is an over-temperature area, execute step 725; if the area is a non-over-temperature area, execute step 726.

[0235] Step 725: Stop applying the AC signal to each electrode unit 12 in the over-temperature area and execute step 731;

[0236] Step 726: Determine whether the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the first preset temperature t1, execute step 727. If the temperature of each electrode unit 12 in the non-overtemperature area exceeds the first preset temperature t1, execute step 728.

[0237] Step 727: Continue applying the AC signal to each electrode unit 12 in the non-overtemperature area of ​​the electrode sheet 10 by increasing the voltage or current amplitude of the currently applied AC signal and execute step 731;

[0238] Step 728: Determine whether the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the second preset temperature t2. If the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the second preset temperature t2, execute step 729. If the temperature of each electrode unit 12 in the non-overtemperature area exceeds the second preset temperature t2, execute step 730.

[0239] Step 729: Continue applying the AC signal to each electrode unit 12 in the non-overtemperature region of the electrode sheet 10 in a manner that maintains the voltage or current amplitude of the currently applied AC signal unchanged and execute step 731;

[0240] Step 730: Continue applying the AC signal to each electrode unit 12 in the non-overtemperature area of ​​the electrode sheet 10 by reducing the voltage or current amplitude of the currently applied AC signal and execute step 731;

[0241] Step 731: Combining and controlling the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to re-acquire the temperature of each electrode unit 12 of the electrode sheet 10 and selecting to execute step 732 or step 734. The temperature of each electrode unit 12 of the electrode sheet 10 includes the temperature of each electrode unit 12 in the over-temperature area and the temperature of each electrode unit 12 in the non-over-temperature area.

[0242] Step 732: Determine whether the temperature of each electrode unit 12 in the over-temperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the over-temperature area does not exceed the first preset temperature t1, execute step 733. If the temperature of each electrode unit 12 in the over-temperature area exceeds the first preset temperature t1, return to step 731.

[0243] Step 733: re-determine the area as a non-overtemperature area and execute step 734;

[0244] Step 734: Determine whether the temperatures of the electrode units 12 in the non-overtemperature area do not exceed the first preset temperature t1. If the temperatures of the electrode units 12 in the non-overtemperature area do not exceed the first preset temperature t1, execute step 735. If any of the temperatures of the electrode units 12 in the non-overtemperature area exceeds the first preset temperature t1, execute step 736.

[0245] Step 735: Continue applying the AC signal to each electrode unit 12 in the non-overtemperature area by increasing the voltage or current amplitude of the currently applied AC signal and return to step 712;

[0246] Step 736: Determine whether the temperatures of the electrode units 12 in the non-overtemperature region do not exceed the second preset temperature t2. If the temperatures of the electrode units 12 in the non-overtemperature region do not exceed the second preset temperature t2, execute step 737. If any of the temperatures of the electrode units 12 in the non-overtemperature region exceeds the second preset temperature t2, execute step 738.

[0247] Step 737: Continue applying the AC signal to each electrode unit 12 in the non-overtemperature area in a manner that maintains the voltage or current amplitude of the currently applied AC signal unchanged and return to step 712;

[0248] Step 738: Determine whether the temperatures of the electrode units 12 in the non-overtemperature area do not exceed the preset temperature threshold t0. If the temperatures of the electrode units 12 in the non-overtemperature area do not exceed the preset temperature threshold t0, execute step 739. If any of the temperatures of the electrode units 12 in the non-overtemperature area exceeds the preset temperature threshold t0, return to step 719.

[0249] Step 739 : Continue applying the AC signal to each electrode unit 12 in the non-overtemperature area by reducing the voltage or current amplitude of the currently applied AC signal and return to step 712 .

[0250] Among them, Figure 22 As shown, the process of combining and controlling the grounding switch 25 and the bidirectional switch 26 electrically connected to the corresponding electrode sheet 10 in step 711 to apply an AC signal to each electrode unit 12 of the electrode sheet is specifically as follows:

[0251] Disconnect all grounding switches 25 electrically connected to the corresponding electrode sheet 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode sheet 10 to one end that applies an AC signal to each electrode unit 12; or disconnect all grounding switches 25 electrically connected to the corresponding electrode sheet 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode sheet 10 to one end that electrically connects each electrode unit 12 to the AC signal line 28; or disconnect all grounding switches 25 electrically connected to the corresponding electrode sheet 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode sheet 10 to their respective input ends 2.

[0252] The process of obtaining the temperature of each electrode unit 12 of the electrode sheet 10 in steps 712, 722, and 731 is specifically as follows:

[0253] Control the bidirectional switch 26 electrically connected to the electrode sheet 10 to switch from one end thereof for applying an AC signal to each electrode unit 12 to one end thereof for collecting temperature of each electrode unit 12, and sequentially close the grounding switch 25 electrically connected to the electrode unit 12 of the electrode sheet 10 in time division to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or control the bidirectional switch 26 electrically connected to the electrode sheet 10 to switch from the input end 2 thereof for applying an AC signal to each electrode unit 12 to the collecting end 1 thereof, and sequentially close the grounding switch 25 electrically connected to the electrode unit 12 of the electrode sheet 10 in time division to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or control the bidirectional switch 26 electrically connected to the electrode sheet 10 to switch from the input end 2 thereof for applying an AC signal to each electrode unit 12 to the collecting end 1 thereof, and sequentially close the grounding switch 25 electrically connected to the electrode unit 12 of the electrode sheet 10 in time division to obtain the temperature of each electrode unit 12 of the electrode sheet 10; 0, so that each electrode unit 12 of the electrode sheet 10 is electrically connected to the AC signal line 28 to switch to each electrode unit 12 being electrically connected to the corresponding analog-to-digital converter 23, and the grounding switch 25 electrically connected to each electrode unit 12 of the electrode sheet 10 is closed in time and sequence to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or the bidirectional switching switch 26 electrically connected to the electrode sheet 10 is controlled so that each electrode unit 12 of the electrode sheet 10 is switched from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal, and the grounding switch 25 electrically connected to each electrode unit 12 of the electrode sheet 10 is closed in time and sequence to obtain the temperature of each electrode unit 12 of the electrode sheet 10.

[0254] The first preset temperature in steps 713, 723, 726, 732, and 734 is 40°C to 40.3°C, preferably 40.2°C. The second preset temperature in steps 715, 728, and 736 is 40.4°C to 40.6°C, preferably 40.5°C. The preset temperature threshold in steps 717 and 738 is 41°C to 41.5°C, preferably 41°C. The preset quantity threshold in step 720 is preferably 2.

[0255] The process of continuing to apply the AC signal in steps 714, 716, 718, 727, 729, 730, 735, 737, and 739 is specifically as follows:

[0256] The ground switch 25 connected to the electrode unit 12 to which the AC signal is to be continuously applied is opened, and at the same time, the bidirectional switch 26 connected to the electrode unit 12 to which the AC signal is to be continuously applied is controlled to connect the AC signal transmission path connected to the electrode unit 12 to which the AC signal is to be continuously applied, so as to continuously apply the AC signal to the electrode unit 12 to which the AC signal is to be continuously applied; or the ground switch 25 connected to the electrode unit 12 to which the AC signal is to be continuously applied is opened, and at the same time, the bidirectional switch 26 connected to the electrode unit 12 to which the AC signal is to be continuously applied is controlled to switch from the collection end 1 to the input end 2, so as to continuously apply the AC signal to the electrode unit 12 to which the AC signal is to be continuously applied; or the ground switch 25 connected to the electrode unit 12 to which the AC signal is to be continuously applied is opened, and at the same time, the bidirectional switch 26 connected to the electrode unit 12 to which the AC signal is to be continuously applied is controlled to electrically connect the input end 2 to the AC signal line 28, so as to continuously apply the AC signal to the electrode unit 12 to which the AC signal is to be continuously applied; or the ground switch 25 connected to the electrode unit 12 to which the AC signal is to be continuously applied is opened, and at the same time, the bidirectional switch 26 connected to the electrode unit 12 to which the AC signal is to be continuously applied is controlled to close the input end 2 and open the collection end 1, so as to continuously apply the AC signal to the electrode unit 12 to which the AC signal is to be continuously applied; or the ground switch 25 connected to the electrode unit 12 to which the AC signal is to be continuously applied is opened, and at the same time, the bidirectional switch 26 connected to the electrode unit 12 to which the AC signal is to be continuously applied is controlled to switch from the transmission temperature detection signal to the AC signal application.

[0257] The increasing the voltage or current amplitude of the currently applied AC signal in steps 714, 727, and 735 is specifically increasing the voltage of the currently applied AC signal by a DC voltage amplitude increment of 0.03 V per second.

[0258] The continuously applying the AC signal in a manner of reducing the voltage or current amplitude of the currently applied AC signal in steps 718, 730, and 739 is specifically continuously applying the AC signal in a manner of 5 V less than the voltage amplitude of the currently applied AC signal and lasting for 3 minutes.

[0259] The process of stopping applying the AC signal to each electrode unit 12 of the electrode sheet 10 described in step 721 is specifically as follows: controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to disconnect the electrical connection between each electrode unit 12 of the electrode sheet 10 and the AC signal line 28; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from the end at which the AC signal is applied to each electrode unit 12 to the end at which the temperature is collected by each electrode unit 12; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from the input end 2 at which the AC signal is applied to each electrode unit 12 to the collection end 1; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch the electrode sheet 10 from the electrical connection between each electrode unit 12 and the AC signal line 28 to the electrical connection between each electrode unit 12 and the corresponding analog-to-digital converter 23; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch each electrode unit 12 of the electrode sheet 10 from transmitting the AC signal to transmitting the DC signal or the temperature detection signal.

[0260] The process of stopping applying the AC signal to each electrode unit 12 in the over-temperature area described in step 725 is specifically as follows: controlling the bidirectional switch 26 electrically connected to each electrode unit 12 in the over-temperature area to disconnect the electrical connection between each electrode unit 12 in the over-temperature area and the AC signal line 28; or controlling the bidirectional switch 26 electrically connected to each electrode unit 12 in the over-temperature area to switch all ends from the end where the AC signal is applied to each electrode unit 12 in the over-temperature area to the end where the temperature of each electrode unit 12 in the over-temperature area is collected; or

[0261] Control the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area so that the input end 2 for applying the AC signal to each electrode unit 12 in the over-temperature area is switched to its collection end 1; or control the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area so that each electrode unit 12 in the over-temperature area is switched from being electrically connected to the AC signal line 28 to being electrically connected to the corresponding analog-to-digital converter 23; or control the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area so that each electrode unit 12 in the over-temperature area is switched from transmitting AC signals to transmitting DC signals or temperature detection signals.

[0262] In the aforementioned application method, the tumor therapy field system 100 includes at least two pairs of electrode sheets 10, which alternately apply alternating electric fields in different directions. Each electrode sheet 10 can alternate between applying an AC signal and transmitting a temperature detection signal. The electrode units 12 of the same electrode sheet 10 apply AC signals and DC signals for temperature measurement at different, non-overlapping time periods.

[0263] The first controller 22 in the adapter 20 of the tumor electric field therapy system 100 or the electric field generator 30 further has a third preset temperature t3, which is higher than the second preset temperature t2 but still lower than the preset temperature threshold t0. The third preset temperature t3 is closer to the preset temperature threshold t0 than the second preset temperature t2. The application further provides an alternating current signal control method based on a temperature detection signal, which is used for the tumor electric field therapy system. Figure 23 As shown in the figure, the alternating current signal control method comprises:

[0264] Step 810: starting the tumor electric field therapy system 100;

[0265] Step 811: combining the control of the ground switch 25 and the bidirectional switch 26 connected to the electrode sheet 10 to apply an alternating current signal to each electrode unit 12 of the electrode sheet 10;

[0266] Step 812: combining the control of the ground switch 25 and the bidirectional switch 26 connected to the electrode sheet 10 to obtain the temperature of each electrode unit 12 of the electrode sheet 10;

[0267] Step 813: determining whether there is an electrode unit 12 with a temperature exceeding the first preset temperature t1, and when there is no electrode unit 12 with a temperature exceeding the first preset temperature t1, executing step 814, and when there is an electrode unit 12 with a temperature exceeding the first preset temperature t1, executing step 815;

[0268] Step 814: continuing to apply the alternating current signal to each electrode unit 12 of the electrode sheet 10 in a manner of increasing the voltage or current amplitude of the currently applied alternating current signal and returning to step 812;

[0269] Step 815: determining whether there is an electrode unit 12 with a temperature exceeding the second preset temperature t2, and when there is no electrode unit 12 with a temperature exceeding the second preset temperature t2, executing step 816, and when there is an electrode unit 12 with a temperature exceeding the second preset temperature t2, executing step 817;

[0270] Step 816: continuing to apply the alternating current signal to each electrode unit 12 of the electrode sheet 10 in a manner of keeping the voltage or current amplitude of the currently applied alternating current signal unchanged and returning to step 812;

[0271] Step 817: determining whether there is an electrode unit 12 with a temperature exceeding the third preset temperature t3, and when there is no electrode unit 12 with a temperature exceeding the third preset temperature t3, executing step 818, and when there is an electrode unit with a temperature exceeding the third preset temperature t3, executing step 819;

[0272] Step 818: Continue applying the AC signal to all electrode units 12 of the electrode sheet 10 in a manner of reducing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0273] Step 819: Determine whether there is an electrode unit 12 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 12 whose temperature exceeds the preset temperature threshold t0, execute step 820; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute step 821.

[0274] Step 820: Continue applying the AC signal to all electrode units 12 of the electrode sheet 10 in a manner of reducing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0275] Step 821: Determine the number of over-temperature regions and execute step 822, wherein the over-temperature region is a region containing electrode units whose temperatures exceed a preset temperature threshold t0, and the non-over-temperature region is a region in which the temperatures of all electrode units do not exceed the preset temperature threshold t0;

[0276] Step 822: Determine whether the number of over-temperature areas exceeds a preset number threshold. If the number of over-temperature areas exceeds the preset number threshold, execute step 823. If the number of over-temperature areas does not exceed the preset number threshold, execute step 826.

[0277] Step 823: Stop applying the AC signal to each electrode unit 12 of the electrode sheet 10 and execute step 824;

[0278] Step 824: Combine and control the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to obtain the temperature of each electrode unit 12 of the electrode sheet 10 and execute step 825;

[0279] Step 825: Determine whether there is an electrode unit 12 with a temperature exceeding the first preset temperature t1. If no electrode unit 12 with a temperature exceeding the first preset temperature t1 exists in the electrode sheet 10, the process returns to step 811. If no electrode unit 12 with a temperature exceeding the first preset temperature t1 exists in the electrode sheet 10, the process returns to step 824.

[0280] Step 826: Distinguish between an over-temperature area and a non-over-temperature area based on whether the area contains an electrode unit 12 whose temperature exceeds the preset temperature threshold t0. If the area is an over-temperature area, execute step 827; if the area is a non-over-temperature area, execute step 828.

[0281] Step 827: Stop applying the AC signal to each electrode unit 12 in the over-temperature area and execute step 835;

[0282] Step 828: Determine whether the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the first preset temperature t1, execute step 829. If the temperature of each electrode unit 12 in the non-overtemperature area exceeds the first preset temperature t1, execute step 830.

[0283] Step 829: Continue applying the AC signal to each electrode unit 12 in the non-overtemperature region of the electrode sheet 10 by increasing the voltage or current amplitude of the currently applied AC signal and execute step 835;

[0284] Step 830: Determine whether the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the second preset temperature t2. If the temperature of each electrode unit 12 in the non-overtemperature area does not exceed the second preset temperature t2, execute step 831. If the temperature of each electrode unit 12 in the non-overtemperature area exceeds the second preset temperature t2, execute step 832.

[0285] Step 831: Continue applying the AC signal to each electrode unit 12 in the non-overtemperature area of ​​the electrode sheet 10 in a manner that maintains the voltage or current amplitude of the currently applied AC signal unchanged and execute step 835;

[0286] Step 832: Determine whether any of the electrode units 12 in the non-overtemperature region has a temperature exceeding the third preset temperature t3. If none of the electrode units 12 in the non-overtemperature region has a temperature exceeding the third preset temperature t3, execute step 833. If any of the electrode units 12 in the non-overtemperature region has a temperature exceeding the third preset temperature t3, execute step 834.

[0287] Step 833: Continue applying the AC signal to each electrode unit 12 in the non-overtemperature area of ​​the electrode sheet 10 by reducing the voltage or current amplitude of the currently applied AC signal and execute step 835;

[0288] Step 834: Continue applying the AC signal to each electrode unit 12 in the non-overtemperature area of ​​the electrode sheet 10 in a manner that further reduces the voltage or current amplitude of the currently applied AC signal and execute step 835;

[0289] Step 835: Combining and controlling the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to re-acquire the temperature of each electrode unit 12 of the electrode sheet 10 and selecting to execute step 836 or step 838. The temperature of each electrode unit 12 of the electrode sheet 10 includes the temperature of each electrode unit 12 in the over-temperature area and the temperature of each electrode unit 12 in the non-over-temperature area.

[0290] Step 836: Determine whether the temperature of each electrode unit 12 in the over-temperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the over-temperature area does not exceed the first preset temperature t1, execute step 837. If the temperature of each electrode unit 12 in the over-temperature area exceeds the first preset temperature t1, return to step 835.

[0291] Step 837: re-determine the area as a non-overtemperature area and execute step 838;

[0292] Step 838: Determine whether the temperatures of the electrode units 12 in the non-overtemperature area do not exceed the first preset temperature t1. If the temperatures of the electrode units 12 in the non-overtemperature area do not exceed the first preset temperature t1, execute step 839. If any of the temperatures of the electrode units 12 in the non-overtemperature area exceeds the first preset temperature t1, execute step 840.

[0293] Step 839: Continue applying the AC signal to each electrode unit 12 in the non-overtemperature area by increasing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0294] Step 840: Determine whether the temperatures of the electrode units 12 in the non-overtemperature region do not exceed the second preset temperature t2. If the temperatures of the electrode units 12 in the non-overtemperature region do not exceed the second preset temperature t2, execute step 841. If any of the temperatures of the electrode units 12 in the non-overtemperature region exceeds the second preset temperature t2, execute step 842.

[0295] Step 841: Continue applying the AC signal to each electrode unit 12 in the non-overtemperature area in a manner that maintains the voltage or current amplitude of the currently applied AC signal unchanged and return to step 812;

[0296] Step 842: Determine whether the temperatures of the electrode units 12 in the non-overtemperature region do not exceed the third preset temperature t3. If the temperatures of the electrode units 12 in the non-overtemperature region do not exceed the third preset temperature t3, execute step 843. If any of the temperatures of the electrode units 12 in the non-overtemperature region exceeds the third preset temperature t3, execute step 844.

[0297] Step 843: Continue applying the AC signal to each electrode unit 12 in the non-overtemperature area by reducing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0298] Step 844: Determine whether the temperatures of the electrode units 12 in the non-overtemperature region do not exceed the preset temperature threshold t0. If the temperatures of the electrode units 12 in the non-overtemperature region do not exceed the preset temperature threshold t0, execute step 845. If any of the temperatures of the electrode units 12 in the non-overtemperature region exceeds the preset temperature threshold t0, return to step 821.

[0299] Step 845 : Continue applying the AC signal to each electrode unit 12 in the non-overtemperature area in a manner of further reducing the voltage or current amplitude of the currently applied AC signal and return to step 812 .

[0300] The process of combining and controlling the grounding switch 25 and the bidirectional switch 26 electrically connected to the corresponding electrode sheet 10 in step 811 to apply an AC signal to each electrode unit 12 of the electrode sheet is as follows:

[0301] Disconnect all grounding switches 25 electrically connected to the corresponding electrode sheet 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode sheet 10 to one end that applies an AC signal to each electrode unit 12; or disconnect all grounding switches 25 electrically connected to the corresponding electrode sheet 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode sheet 10 to one end that electrically connects each electrode unit 12 to the AC signal line 28; or disconnect all grounding switches 25 electrically connected to the corresponding electrode sheet 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode sheet 10 to their respective input ends 2.

[0302] The process of obtaining the temperature of each electrode unit 12 of the electrode sheet 10 in steps 812, 824, and 835 is specifically as follows:

[0303] Control the bidirectional switch 26 electrically connected to the electrode sheet 10 to switch from one end thereof for applying an AC signal to each electrode unit 12 to one end thereof for collecting temperature of each electrode unit 12, and sequentially close the grounding switch 25 electrically connected to the electrode unit 12 of the electrode sheet 10 in time division to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or control the bidirectional switch 26 electrically connected to the electrode sheet 10 to switch from the input end 2 thereof for applying an AC signal to each electrode unit 12 to the collecting end 1 thereof, and sequentially close the grounding switch 25 electrically connected to the electrode unit 12 of the electrode sheet 10 in time division to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or control the bidirectional switch 26 electrically connected to the electrode sheet 10 to switch from the input end 2 thereof for applying an AC signal to each electrode unit 12 to the collecting end 1 thereof, and sequentially close the grounding switch 25 electrically connected to the electrode unit 12 of the electrode sheet 10 in time division to obtain the temperature of each electrode unit 12 of the electrode sheet 10; 0, so that each electrode unit 12 of the electrode sheet 10 is electrically connected to the AC signal line 28 to switch to each electrode unit 12 being electrically connected to the corresponding analog-to-digital converter 23, and the grounding switch 25 electrically connected to each electrode unit 12 of the electrode sheet 10 is closed in time and sequence to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or the bidirectional switching switch 26 electrically connected to the electrode sheet 10 is controlled so that each electrode unit 12 of the electrode sheet 10 is switched from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal, and the grounding switch 25 electrically connected to each electrode unit 12 of the electrode sheet 10 is closed in time and sequence to obtain the temperature of each electrode unit 12 of the electrode sheet 10.

[0304] The first preset temperature in steps 813, 825, 828, 836, and 838 is 40°C to 40.3°C, preferably 40.2°C. The second preset temperature in steps 815, 830, and 840 is 40.4°C to 40.6°C, preferably 40.5°C. The third preset temperature in steps 817, 832, and 842 is 40.7°C to 40.9°C, preferably 40.8°C. The preset temperature threshold in steps 819 and 844 is 41°C to 41.5°C, preferably 41°C. The preset quantity threshold in step 822 is preferably 2.

[0305] The process of continuing to apply the AC signal described in steps 814, 816, 818, 820, 829, 831, 833, 834, 839, 841, 843, and 845 is specifically as follows: disconnecting the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied, and simultaneously controlling the bidirectional switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied to conduct the AC signal transmission path electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied, thereby continuing to apply the AC signal to the electrode unit 12 to which the AC signal needs to be continuously applied; or disconnecting the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied, and simultaneously controlling the bidirectional switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied to switch from its respective collection end 1 to its respective input end 2, thereby continuing to apply the AC signal to the electrode unit 12 to which the AC signal needs to be continuously applied; Or disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to continue to be applied, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to continue to be applied so that their respective input ends 2 are electrically connected to the AC signal line 28 so as to continue to apply the AC signal to the electrode unit 12 to which the AC signal needs to continue to be applied; or disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to continue to be applied, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to continue to be applied so that their respective input ends 2 are closed and the collection end 1 is disconnected so as to continue to apply the AC signal to the electrode unit 12 to which the AC signal needs to continue to be applied; or disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to continue to be applied, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to continue to be applied so that the electrode unit 12 to which the AC signal needs to continue to be applied switches from transmitting the temperature detection signal to applying the AC signal.

[0306] The method of increasing the voltage or current amplitude of the currently applied AC signal in step 814, step 829, and step 839 is to continue applying the AC signal by boosting the currently applied AC signal with a DC voltage amplitude increment of 0.03V per second and then continuing to apply the AC signal.

[0307] Continuing to apply the AC signal in a manner of reducing the voltage or current amplitude of the currently applied AC signal as described in step 818, step 820, step 833, step 834, step 843 and step 845 is specifically continuing to apply the AC signal in a manner of 5V less than the voltage amplitude of the currently applied AC signal and for 3 minutes.

[0308] The process of stopping applying the AC signal to each electrode unit 12 of the electrode sheet 10 described in step 823 is specifically as follows: controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to disconnect the electrical connection between each electrode unit 12 of the electrode sheet 10 and the AC signal line 28; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from one end at which each electrode unit 12 applies the AC signal to one end at which each electrode unit 12 performs temperature acquisition; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from the input end 2 at which each electrode unit 12 applies the AC signal to its acquisition end 1; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch the electrode sheet 10 from the electrical connection between each electrode unit 12 and the AC signal line 28 to the electrical connection between each electrode unit 12 and the corresponding analog-to-digital converter 23; or controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch each electrode unit 12 of the electrode sheet 10 from transmitting the AC signal to transmitting the DC signal or the temperature detection signal.

[0309] The process of stopping applying the AC signal to each electrode unit 12 in the over-temperature area described in step 827 is specifically as follows: controlling the bidirectional switch 26 electrically connected to each electrode unit 12 in the over-temperature area to disconnect the electrical connection between each electrode unit 12 in the over-temperature area and the AC signal line 28; or controlling the bidirectional switch 26 electrically connected to each electrode unit 12 in the over-temperature area to switch all ends from the end where the AC signal is applied to each electrode unit 12 in the over-temperature area to the end where the temperature of each electrode unit 12 in the over-temperature area is collected; or

[0310] Control the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area so that the input end 2 for applying the AC signal to each electrode unit 12 in the over-temperature area is switched to its collection end 1; or control the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area so that each electrode unit 12 in the over-temperature area is switched from being electrically connected to the AC signal line 28 to being electrically connected to the corresponding analog-to-digital converter 23; or control the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature area so that each electrode unit 12 in the over-temperature area is switched from transmitting AC signals to transmitting DC signals or temperature detection signals.

[0311] When the tumor electric field therapy system 100 is in a standby state before starting operation, no AC signal is applied to the electrode unit 12. The first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls the bidirectional switch 26 to switch to the acquisition end 1, the grounding switches 25 are turned on in sequence, and the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to each row of electrode units 12 in sequence.

[0312] When the first ground switch 25-1 is turned on, the other ground switches 25 are all turned off, and the bidirectional switch 26 is set to the collection end 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12;

[0313] When the second ground switch 25-2 is turned on, the other ground switches 25 are all turned off, and the bidirectional switch 26 is set to the collection end 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12;

[0314] When the third ground switch 25-3 is turned on, the other ground switches 25 are all turned off, and the bidirectional switch 26 is set to the collection end 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12;

[0315] When the fourth ground switch 25-4 is turned on, the other ground switches 25 are all turned off, and the bidirectional switch 26 is set to the collection end 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12.

[0316] The first controller 22 receives the temperature detection signal of the temperature sensor 14 corresponding to each electrode unit 12 through the analog-to-digital converter 23, and transmits the signal to the AC signal generator 34 of the electric field generator 30 through the first communication unit 27 and the second communication unit 33, so as to control or adjust the alternating current signal applied to each electrode unit 12 through the second controller 32.

[0317] When the above methods are applied to the electrode sheets (10D, 10E, 10F, 10G, and 10J) of other embodiments, the ground switches 25 in the idle-off state and / or the bidirectional switches 26 in the idle-off state that are not electrically connected to the corresponding electrode sheets (10D, 10E, 10F, 10G, and 10J) exist on the adapter 20, and the corresponding ground switches 25 in the idle-off state and / or the bidirectional switches 26 in the idle-off state do not need to be controlled.

[0318] Although various operations are depicted in the drawings in a particular order, this should not be understood as requiring that such operations be performed in the particular order shown or in sequential order, or that all illustrated operations be performed, to achieve desirable results.

[0319] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit them. Although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some or all of the technical features therein. These modifications or replacements do not deviate the essence of the corresponding technical solutions from the scope of the technical solutions of the embodiments of the present application, and they should all be included in the scope of the claims and specification of the present application. In particular, as long as there is no structural conflict, the various technical features mentioned in the various embodiments can be combined in any way. The present application is not limited to the specific embodiments disclosed herein, but includes all technical solutions that fall within the scope of the claims.

Claims

1. A tumor electric field treatment system, characterized in that: include: At least one pair of electrode sheets, the electrode sheet includes a plurality of electrode units and a flexible circuit board, the plurality of electrode units are divided into a plurality of row groups and a plurality of column groups on the circuit, each of the electrode units includes a temperature sensor having a signal terminal and a ground terminal; the flexible circuit board is configured for the plurality of electrode units to be arranged thereon at intervals, and a plurality of conductive traces are embedded in the flexible circuit board, the plurality of conductive traces include: a plurality of grounding lines and a plurality of dual-purpose signal lines, the plurality of grounding lines are connected to the plurality of row groups in a one-to-one correspondence, each of the grounding lines is configured to short-circuit the ground terminals of the temperature sensors of the electrode units in the corresponding row group to ground, and the ground terminals of the temperature sensors in the same row group are short-circuited through the same grounding line, The ground terminals of the temperature sensors in different row groups are connected in parallel via different ground lines, and the multiple ground lines are grounded in sequence when performing temperature detection. The multiple dual-purpose signal lines are connected to the multiple column groups in a one-to-one correspondence, the signal terminals of the temperature sensors in the same column group are short-circuited via the same dual-purpose signal line, and the signal terminals of the temperature sensors in different column groups are connected in parallel via different dual-purpose signal lines. Each dual-purpose signal line is configured to transmit both an alternating current signal and a direct current signal to each electrode unit in the corresponding column group, or to transmit a temperature detection signal detected by each electrode unit in the corresponding column group. an electric field generator configured to provide an alternating current signal to a plurality of electrode units of the electrode sheet via a dual-purpose signal line of the electrode sheet; and An adapter is connected between the electrode sheet and the electric field generator, has multiple groups of multi-channel circuit lines and is configured to transmit the alternating current signal generated by the electric field generator to the dual-purpose signal line corresponding to the electrode sheet through the corresponding circuit lines in the corresponding group of circuit lines, and is also configured to receive the temperature detection signal output by the dual-purpose signal line corresponding to the electrode sheet through the corresponding circuit lines in the corresponding group of circuit lines. Some of the circuit lines in each group of multi-channel circuit lines are electrically connected one-to-one with the dual-purpose signal lines and the ground lines corresponding to the electrode sheet, and at least one circuit line in each group of multi-channel circuit lines is in an idle state and is not electrically connected to the dual-purpose signal line corresponding to the electrode sheet or the ground line corresponding to the electrode sheet.

2. The tumor electric field treatment system according to claim 1, characterized in that: The adapter also includes multiple groups of bidirectional switching switches electrically connected one-to-one with multiple groups of circuit lines, each group of bidirectional switching switches is electrically connected one-to-one with the corresponding circuit lines in the corresponding group and includes multiple bidirectional switching switches, at least some of the multiple bidirectional switching switches in each group are electrically connected one-to-one with the multiple dual-purpose signal lines of the corresponding electrode sheet to control the multiple dual-purpose signal lines of the corresponding electrode sheet to transmit alternating current signals or temperature detection signals.

3. The tumor electric field treatment system according to claim 2, characterized in that: The adapter includes multiple groups of grounding switches electrically connected one-to-one with multiple groups of circuit lines. Each group of grounding switches is electrically connected one-to-one with the corresponding circuit lines in the corresponding group and includes multiple grounding switches. At least some of the multiple grounding switches in each group are electrically connected one-to-one with the multiple grounding lines of the corresponding electrode sheets and control the conduction or disconnection of the multiple grounding lines of the electrode sheets electrically connected to them.

4. The tumor electric field treatment system according to claim 3, characterized in that: At least one bidirectional switch or at least one grounding switch in each group of bidirectional switches and each group of grounding switches of the adapter is in an idle state. The bidirectional switch in the idle state is not electrically connected to the dual-purpose signal line corresponding to the electrode sheet, and the grounding switch in the idle state is not electrically connected to the grounding line corresponding to the electrode sheet.

5. The tumor electric field treatment system according to claim 3 or 4, characterized in that: Each group of multiple circuit lines of the adapter further includes: An AC signal line is configured to provide an alternating current signal to each of the electrode units in the corresponding column group of the electrode sheet through the multiple dual-purpose signal lines of the corresponding electrode sheet.

6. The tumor electric field treatment system according to claim 5, characterized in that: The adapter also includes: a plurality of groups of analog-to-digital converters, each group of analog-to-digital converters being electrically connected to the multiplexed signal line of the corresponding electrode sheet through a corresponding group of multiplexed circuit lines and being configured to receive the temperature detection signal transmitted by the multiplexed signal line of the corresponding electrode sheet through the corresponding group of circuit lines and convert the temperature detection signal from an analog signal to a digital signal; Each group of the analog-to-digital converters includes multiple detection channels, and each of the bidirectional switches also has an acquisition end electrically connected to a corresponding detection channel in the corresponding analog-to-digital converter and an input end electrically connected to the AC signal line.

7. The tumor electric field treatment system according to claim 3 or 4, characterized in that: The number of the grounding switches in each group is 4, and / or the number of the bidirectional switches in each group is 5.

8. The tumor electric field treatment system according to claim 1, characterized in that: Each of the electrode units includes a dielectric element for transmitting an alternating current signal, and the dielectric element of each of the electrode units is short-circuited with a signal terminal of a corresponding temperature sensor.

9. The tumor electric field treatment system according to claim 8, characterized in that: Each of the electrode units further includes a diode connected in series with a temperature sensor, and the temperature sensor is grounded via the diode connected in series with the temperature sensor.

10. The tumor electric field treatment system according to claim 1, characterized in that: The plurality of electrode units are arranged in a plurality of rows and columns in a spatial structure, and the flexible circuit board is provided with a connection portion connecting two adjacent electrode units, wherein the electrode sheet is provided with a gap formed between two adjacent electrode units along the column direction and along the row direction.

11. The tumor electric field treatment system according to claim 3 or 4, characterized in that: When performing temperature detection on each electrode unit of the electrode sheet, the multiple bidirectional switches electrically connected to the electrode sheet are placed at their respective collection ends, and only one of the multiple grounding switches electrically connected to the electrode sheet is turned on at the same time, and the others are turned off.

12. The tumor electric field treatment system according to claim 3 or 4, characterized in that: When an alternating current signal is applied to each electrode unit of the electrode sheet, all or part of the multiple bidirectional switches electrically connected to the electrode sheet are placed at the input end, and all of the multiple grounding switches electrically connected to the electrode sheet are disconnected.

13. The tumor electric field treatment system according to claim 6, characterized in that: The adapter also includes: The first controller is connected to the multiple groups of grounding switches and the multiple groups of bidirectional switches respectively, and is configured to: for sequentially and cyclically controlling the on / off states of a plurality of the grounding switches in each group of grounding switches, thereby sequentially and individually conducting each grounding line in the plurality of grounding lines of the corresponding electrode sheet; and It is used to control the switching states of multiple bidirectional switches in each group of bidirectional switches, so that each bidirectional switch is placed at the collection end to output a temperature detection signal or each bidirectional switch is placed at the input end to transmit an AC signal.

14. The tumor electric field treatment system according to claim 13, characterized in that: The adapter also includes: The first communication unit is configured to obtain the digital signals output by the multiple groups of analog-to-digital converters and send the digital signals to the electric field generator.

15. The tumor electric field treatment system according to claim 14, characterized in that: The electric field generator is further configured to control or adjust an alternating current signal provided to a corresponding electrode unit among the plurality of electrode units of the corresponding electrode sheet according to the received digital signal.

16. The tumor electric field treatment system according to claim 14, wherein: The first communication unit is controlled by the first controller and serially transmits the digital signal converted by the analog-to-digital converter.

17. A temperature detection method, characterized in that: Applied to the tumor electric field treatment system according to any one of claims 1 to 16, the method comprises the following steps: Turning on all the collecting ends of the multiplexed signal lines corresponding to the plurality of column groups of the corresponding electrode sheets; and Each of the multiple grounding lines corresponding to the plurality of row groups of the electrode sheet is sequentially and time-dividedly turned on to collect the temperature detection signal of each electrode unit in each row group of the electrode sheet by row through the multiplexed signal line.

18. A method for detecting temperature anomaly, characterized in that: The temperature anomaly is determined by using the temperature detection signal of each electrode unit of the electrode sheet obtained according to the method of claim 17 .

19. The method according to claim 18, characterized in that The temperature abnormality determination of the tumor electric field treatment system includes the following steps: comparing the obtained temperature of each of the electrode units with a preset temperature threshold; and It is determined whether the temperature of the electrode sheet is abnormal according to the comparison result.

20. The method according to claim 19, characterized in that The comparison result includes whether the temperature does not exceed the preset temperature threshold or exceeds the preset temperature threshold. Whether the temperature of the electrode sheet is abnormal is determined by the following method: When the temperature of one of the electrode units exceeds a preset temperature threshold, it is determined that the electrode sheet has a temperature abnormality; or When the temperatures of all electrode units do not exceed a preset temperature threshold, it is determined that the electrode sheet has no temperature abnormality.

21. The method according to claim 19 or 20, characterized in that The preset temperature threshold is 40.5°C-41.5°C.

22. The method according to claim 21, characterized in that The preset temperature threshold is 41°C-41.5°C.

23. The method according to claim 22, characterized in that The preset temperature threshold is 41°C.

24. A tumor electric field treatment system, characterized in that: include: At least one pair of electrode sheets, the electrode sheet includes a plurality of electrode units and a flexible circuit board, the plurality of electrode units are divided into a plurality of row groups and a plurality of column groups on the circuit, each of the electrode units includes a temperature sensor having a signal terminal and a ground terminal; the flexible circuit board is configured for the plurality of electrode units to be arranged thereon at intervals, and a plurality of conductive traces are embedded in the flexible circuit board, the plurality of conductive traces including: a plurality of grounding lines and a plurality of dual-purpose signal lines, the plurality of grounding lines are connected to the plurality of row groups in a one-to-one correspondence, the ground terminals of the temperature sensors in the same row group are short-circuited by the same grounding line, and the ground terminals of the temperature sensors in different row groups are respectively connected by different grounding lines. The grounding lines are connected in parallel, and the grounding lines are grounded separately in sequence when performing temperature detection; the dual-purpose signal lines are connected to the column groups in a one-to-one correspondence, the signal ends of the temperature sensors in the same column group are short-circuited by the same dual-purpose signal line, and the signal ends of the temperature sensors in different column groups are connected in parallel by different dual-purpose signal lines, each of the dual-purpose signal lines is configured to transmit an AC signal to each electrode unit in the corresponding column group, and also to transmit a DC signal to the temperature sensor of each electrode unit in the column group, or to transmit a temperature detection signal detected by the temperature sensor of each electrode unit in the column group; and An adapter or an electric field generator electrically connected to the electrode sheet, wherein the adapter or the electric field generator is configured to provide an AC signal to each electrode unit of the electrode sheet or a DC signal to the temperature sensor of each electrode unit of the electrode sheet via the dual-purpose signal line of the electrode sheet.

25. The tumor electric field treatment system according to claim 24, wherein: The electric field generator is configured to control or adjust an alternating current signal applied to each electrode unit of the electrode sheet according to a temperature detection signal of each electrode unit of the electrode sheet.

26. The tumor electric field treatment system according to claim 25, characterized in that The electric field generator has a preset temperature threshold and is configured to: comparing the obtained temperature of each of the electrode units with a preset temperature threshold; and The applied AC signal is controlled or adjusted based on the comparison result.

27. The tumor electric field treatment system according to claim 26, wherein: The electric field generator is configured to: When the temperature detection signals of the electrode units of the electrode sheet obtained do not exceed the preset temperature threshold, continue to apply the alternating current signal to the electrode units of the electrode sheet; or When one of the acquired temperature detection signals of the electrode units of the electrode sheet exceeds a preset temperature threshold, application of the alternating current signal to the electrode units of the electrode sheet is stopped.

28. The tumor electric field treatment system according to claim 27, wherein: Stopping applying AC signals to the electrode units of the electrode sheet includes stopping applying AC signals to all electrode units of the electrode sheet, stopping applying AC signals to electrode units in the electrode sheet whose temperature detection signals exceed a preset temperature threshold, and stopping applying AC signals to all electrode units in the column where the electrode units in the electrode sheet whose temperature detection signals exceed a preset temperature threshold are located.

29. The tumor electric field treatment system according to claim 28, wherein: The electric field generator is further configured to: when stopping applying the AC signal to the electrode unit in the electrode sheet whose temperature detection signal exceeds the preset temperature threshold, continue applying the AC signal to the electrode unit in the electrode sheet whose temperature detection signal does not exceed the preset temperature threshold.

30. The tumor electric field treatment system according to claim 28, wherein: The electric field generator is further configured to: when stopping applying the alternating current signal to all electrode units in the column where the electrode unit whose temperature detection signal exceeds the preset temperature threshold in the electrode sheet is located, continue applying the alternating current signal to all electrode units in the electrode sheet whose temperature detection signal does not exceed the preset temperature threshold and are in a different column from the electrode unit whose temperature detection signal exceeds the preset temperature threshold.

31. The tumor treatment field system according to claim 27, wherein: The comparison result includes not exceeding a preset temperature threshold and exceeding a preset temperature threshold, and not exceeding the preset temperature threshold includes being far below the preset temperature threshold and being close to the preset temperature threshold.

32. The tumor electric field treatment system according to claim 31, wherein: The electric field generator is configured to continue applying an alternating current signal to each electrode unit of the electrode sheet in the following manner when each temperature detection signal of the electrode sheet does not exceed a preset temperature threshold: When the temperature detection signal is much lower than the preset temperature threshold, the AC signal is continued to be applied to each electrode unit of the electrode sheet in a manner of increasing the voltage or current amplitude of the AC signal currently applied to each electrode unit of the electrode sheet or in a manner of keeping the voltage or current amplitude of the AC signal currently applied to each electrode unit of the electrode sheet unchanged; or When the temperature detection signal approaches a preset temperature threshold, the AC signal continues to be applied to each electrode unit of the electrode sheet in a manner that keeps the voltage or current amplitude of the AC signal currently applied to each electrode unit of the electrode sheet unchanged, or continues to apply the AC signal to each electrode unit of the electrode sheet in a manner that reduces the voltage or current amplitude of the AC signal currently applied to each electrode unit of the electrode sheet.

33. The tumor treatment field system according to any one of claims 27 to 32, wherein: The preset temperature threshold is 40.5°C-41.5°C.

34. The tumor electric field treatment system according to claim 33, wherein: The preset temperature threshold is 41°C-41.5°C.

35. The tumor electric field treatment system according to claim 33, wherein: The preset temperature threshold is 41°C.

36. A tumor electric field treatment system, characterized in that: include: At least one pair of electrode sheets, the electrode sheet includes a plurality of electrode units and a flexible circuit board, the plurality of electrode units are divided into a plurality of row groups and a plurality of column groups on the circuit, each of the electrode units includes a temperature sensor having a signal terminal and a ground terminal; the flexible circuit board is configured for the plurality of electrode units to be arranged thereon at intervals, and a plurality of conductive traces are embedded in the flexible circuit board, the plurality of conductive traces including: a plurality of grounding lines and a plurality of dual-purpose signal lines, the plurality of grounding lines are connected to the plurality of row groups in a one-to-one correspondence, the ground terminals of the temperature sensors in the same row group are short-circuited by the same grounding line, and the ground terminals of the temperature sensors in different row groups are respectively connected by different grounding lines. The grounding lines are connected in parallel, and the grounding lines are grounded separately in sequence when performing temperature detection; the dual-purpose signal lines are connected to the column groups in a one-to-one correspondence, the signal ends of the temperature sensors in the same column group are short-circuited by the same dual-purpose signal line, and the signal ends of the temperature sensors in different column groups are connected in parallel by different dual-purpose signal lines; each of the dual-purpose signal lines is configured to transmit an AC signal to each of the electrode units in the corresponding column group, and also to transmit a DC signal to the temperature sensor of each of the electrode units in the column group, or to transmit a temperature detection signal detected by the temperature sensor of each of the electrode units in the column group; and An electric field generator electrically connected to the electrode sheet is configured to control the conduction and disconnection of the ground line and the dual-purpose signal line of the electrode sheet in combination so that the dual-purpose signal line of the electrode sheet cyclically switches between transmitting an AC signal and transmitting a temperature detection signal.

37. The tumor electric field treatment system according to claim 36, wherein: The electric field generator is configured to: disconnect the multiple grounding lines that are electrically connected one-to-one to the grounding ends of the temperature sensors of the electrode units in each row group of the electrode sheet, and at the same time connect the input ends of the multiple dual-purpose signal lines that are electrically connected one-to-one to the electrode units in each column group of the electrode sheet so that the multiple dual-purpose signal lines electrically connected to the electrode sheet transmit alternating current signals to each electrode unit.

38. The tumor electric field treatment system according to claim 37, wherein: The electric field generator is further configured to: connecting the collecting ends of the plurality of dual-purpose signal lines electrically connected to the electrode units of each column group of the electrode sheet to enable the plurality of dual-purpose signal lines electrically connected to the electrode sheet to transmit a DC signal to each electrode unit; and One of the multiple grounding lines electrically connected to the ground ends of the temperature sensors of the electrode units in each row group of the electrode sheet is turned on in sequence and in a time-sharing manner to complete the transmission of the temperature detection signals of each electrode unit in each row group of the electrode sheet in a time-sharing manner and row by row through the multiple dual-purpose signal lines electrically connected to the electrode sheet.

39. The tumor electric field treatment system according to claim 38, wherein: The electric field generator is further configured to: Determining, based on the acquired temperature detection signals of the electrode units, a combined control method for turning on or off the multiple ground lines corresponding to the row groups of the electrode sheet and the multiple dual-purpose signal lines corresponding to the column groups of the electrode sheet; as well as The working state of each electrode unit of the electrode sheet is controlled according to the determined combined control mode of conducting or disconnecting the multiple grounding lines and the multiple dual-purpose signal lines.

40. The tumor electric field treatment system according to claim 39, wherein: The working state of each electrode unit of the electrode sheet includes one of stopping applying the alternating current signal and continuing to collect the temperature detection signal and stopping collecting the temperature detection signal and continuing to apply the alternating current signal.

41. The tumor electric field treatment system according to claim 40, wherein: Continuing to apply the AC signal includes continuing to apply the AC signal in a manner that increases the voltage or current amplitude of the currently applied AC signal, continuing to apply the AC signal in a manner that maintains the voltage or current amplitude of the currently applied AC signal unchanged, and continuing to apply the AC signal in a manner that reduces the voltage or current amplitude of the currently applied AC signal.

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