Bath oil lotion with soothing effect and preparation method thereof

Abstract

The invention belongs to the technical field of washing and protecting products, discloses a bath oil emulsion with soothing effect and a preparation method thereof, the bath oil emulsion with soothing effect, by weight percentage, includes 15-22% sodium tridecyl alcohol polyether sulfate solution, 5-10% sunflower seed oil, 0.8-1.5% glycerophosphorylcholine solution, 0.8-1.6% Kava pepper leaf / root / stem extract solution; the sodium tridecyl alcohol polyether sulfate solution contains 65wt% of sodium tridecyl alcohol polyether sulfate, and the rest are solvents; the glycerophosphorylcholine solution contains 4wt% of glycerophosphorylcholine, and the rest are solvents; the Kava pepper leaf / root / stem extract solution contains 1wt% of Kava pepper leaf / root / stem extract, and the rest are solvents. The present invention is compounded by sodium tridecyl alcohol polyether sulfate, sunflower seed oil, glycerophosphorylcholine, and Kava pepper leaf / root / stem extract, and can produce a significant synergistic effect of improving the soothing effect of the bath oil emulsion with soothing effect.

Description

Technical Field

[0001] The invention relates to the technical field of washing and care products, and in particular to a bath oil emulsion with a soothing effect and a preparation method thereof. Background Art

[0002] Shower gel is a cleaning product specially used for bathing. Compared with traditional soap, shower gel is softer and more stable. Shower gel can not only remove dirt on the body surface, but also make the skin smoother and more elastic. The following are the main functions of shower gel:

[0003] 1. Cleansing the skin: The surfactants contained in shower gel can effectively absorb oil and sweat stains and cleanse the skin. Compared with traditional soap, shower gel has low degreasing power, so it is gentler on the skin and will not cause the skin to lose moisture and oil.

[0004] 2. Soothe the skin: The oil and other nutrients contained in it can provide sufficient moisturizing and nutrition to the skin, relieve various problems such as dry skin, itching and sensitivity, and make the skin smoother and more elastic.

[0005] 3. Regulate skin pH: The emulsifier in the shower gel can neutralize the pH value on the skin surface, keeping the pH value of the skin in a healthy state, thereby reducing the chance of skin damage.

[0006] Therefore, shower gel has become the most popular cleaning product among consumers. Currently, the anionic surfactants used in most shower gels are mainly sodium laureth sulfate, sodium C14-16 olefin sulfonate, soap base, etc.

[0007] For example, prior art 1: Chinese patent application 201710310310.7 discloses a shower gel containing meteorite ingredients and a preparation method thereof, which is composed of the following components: water, disodium ethylenediaminetetraacetic acid (disodium EDTA), sodium laureth sulfate, ammonium lauryl sulfate, sodium lauroyl sarcosinate, cocamidopropyl betaine, coconut oil diethanolamide, meteorite powder, styrene / acrylic acid (ester) copolymer, coconut glucoside, citric acid, polyquaternium-39, fragrance, DMDM ​​hydantoin, and sodium chloride.

[0008] Also like prior art 2: Chinese patent application 201910425826.5 discloses a shower gel and a preparation method thereof, wherein the shower gel components include: 4-6% sodium cocoamphoacetate, 4-5% cocamidopropyl betaine, 8-10% sodium C14-16 olefin sulfonate, 2-5% glycerol, 2-4% cocoyl glucoside, 1-3% oleyl glyceride, 0.05-0.1% perfume / flavor, 0.03-0.2% hamamelis virginiana (witch hazel) extract, 5-7% lauryl lactate, 0.05-0.3% sodium benzoate, 0.08-0.3% panthenol, 0.3-0.5% marshmallow root extract, 0.5-0.8% calendula (marigold) flower extract, 0.9-1.2% activated carbon powder, and the balance is water.

[0009] Prior Art 1 and Prior Art 2 respectively use commonly used surfactants such as sodium lauryl polyether sulfate and sodium C14-16 olefin sulfonate as strong cleaning surfactants. Although such surfactants have strong cleaning power, they also bring the problem of strong degreasing power, resulting in dryness after washing, poor mildness, and a false slippery feeling after rinsing.

[0010] Based on this, prior art 3: Chinese patent 201610574089.1 discloses a foaming shower gel rich in vegetable oil and a preparation method thereof. The foaming shower gel rich in vegetable oil includes the following components in percentage by mass: 10-30% anionic surfactant; 1-15% vegetable oil; 1-20% amphoteric surfactant; 0.05-10% non-ionic surfactant; 0.05-5% thickener; 0.01-1% foam stabilizer; 0.05-1% cationic conditioner; 0.05-1% colorant; 0.05-1% pH adjuster; 0.05-2% antioxidant; an appropriate amount of preservative; and the balance of deionized water.

[0011] Existing technology 3 uses vegetable oil to reduce the degreasing force during the flushing process, which is a technical solution worthy of reference. Although it effectively solves the problem of excessive degreasing force, the formula is insufficient in soothing ingredients and the soothing effect is weak.

[0012] Therefore, the technical problem to be solved by the present invention is: how to further improve the soothing effect of the shower gel. Summary of the invention

[0013] One of the purposes of the present invention is to provide a bath milk with a soothing effect, which produces a synergistic effect of improving the soothing effect of the bath oil with a soothing effect by compounding sodium trideceth sulfate with sunflower seed oil, glycerophosphocholine, and kava leaf / root / stem extract.

[0014] Another object of the present invention is to provide a method for preparing a bath oil with a soothing effect, so as to prepare a bath oil with a soothing effect having excellent soothing effect and meet the skin care needs of consumers.

[0015] To achieve the above object, the present invention provides a bath oil with soothing effect, which comprises, by weight percentage, 15-22% sodium trideceth sulfate solution, 5-10% sunflower seed oil, 0.8-1.5% glycerophosphocholine solution, and 0.8-1.6% kava leaf / root / stem extract solution.

[0016] The sodium tridecyl alcohol polyether sulfate solution contains 65wt% of sodium tridecyl alcohol polyether sulfate, and the rest is solvent; the glycerophosphocholine solution contains 4wt% of glycerophosphocholine, and the rest is solvent; the Piper mesenteriae leaf / root / stem extract solution contains 1wt% of Piper mesenteriae leaf / root / stem extract, and the rest is solvent.

[0017] The technical scheme of the present invention is based on the composite synergy of four active ingredients: sodium tridecyl polyether sulfate, sunflower seed oil, glycerophosphocholine, and kava pepper leaf / root / stem extract. Therefore, the technical scheme that uses sodium tridecyl polyether sulfate solution, glycerophosphocholine solution, and kava pepper leaf / root / stem extract solution with different mass concentrations but different active ingredient contents to achieve the technical effect of the present invention should be included in the protection scope of the present invention.

[0018] Sunflower seed oil is a plant oil emollient that can reduce the degreasing power of the rinsing process. The oil contains unsaturated fatty acids and has a certain soothing and moisturizing effect when used on the skin.

[0019] Sodium trideceth sulfate can accommodate high levels of oil, has low irritation and rich foam. Its combination with sunflower seed oil can give full play to the degreasing effect of sunflower seed oil in reducing the rinsing process.

[0020] The structure of glycerophosphocholine is the same as the polar group of cell membrane phospholipids. It has the properties of moisturizing and rinsing resistance, improves the exfoliation of keratinocytes, and alleviates the erythema irritation caused by surfactants.

[0021] Kava leaf / root / stem extract, an ingredient that antagonizes TRP receptors and directly inhibits neuropeptides, can reduce nerve sensitivity, thereby alleviating neurogenic inflammation and achieving a soothing effect on the skin.

[0022] The present invention unexpectedly finds that when sodium trideceth sulfate, sunflower seed oil, glycerophosphocholine and kava leaf / root / stem extract are compounded, the four ingredients have a significant synergistic effect of improving the soothing effect of the bath oil with a soothing effect.

[0023] At the same time, the present invention finds that sodium trideceth sulfate, when compounded with glycerophosphocholine and kava leaf / root / stem extract on the basis of compounding with sunflower seed oil, can also form micelles that can stay on the skin surface. The micelles can take away dirt such as sebum and microbial bacteria. Moreover, because they stay on the skin surface for a long time, the active ingredients with soothing effects can fully stay and penetrate into the skin to achieve excellent soothing effects. That is to say, when sodium trideceth sulfate, sunflower seed oil, glycerophosphocholine and kava leaf / root / stem extract are compounded, the soothing effect of the bath oil with soothing effects is further improved.

[0024] Furthermore, in addition to the surfactant sodium trideceth sulfate, the bath oil with soothing effect of the present invention also includes 8-24% of other surfactants.

[0025] The surfactant is at least one of sodium cocoyl methyl taurate, sodium lauroamphoacetate, cocamidopropyl betaine, lauryl hydroxysulfobetaine, disodium cocoamphodiacetate, and coco glucoside.

[0026] It should be noted that the sodium trideceth sulfate of the present invention is also a kind of surfactant. However, since sodium trideceth sulfate has a synergistic effect with sunflower seed oil, glycerophosphocholine, and kava leaf / root / stem extract, the additional surfactants defined in the present invention exclude sodium trideceth sulfate. However, sodium trideceth sulfate also plays the role of a surfactant.

[0027] Preferably, the surfactant includes 3-6% sodium cocoyl methyl taurate, 5-10% sodium lauroamphoacetate, and 5-8% cocamidopropyl betaine.

[0028] Furthermore, the bath oil with soothing effect also includes 0.1-0.3% guar hydroxypropyltrimethylammonium chloride and 3-5% acrylic acid (ester) copolymer.

[0029] Furthermore, the bath oil with soothing effect also includes 2.5-5% of glyceryl oleate and / or glyceryl laurate, and the balance is water.

[0030] At the same time, the bath oil with soothing effect of the present invention can also be added with preservatives and other auxiliary agents commonly used in the art as needed.

[0031] Specifically, the bath oil with soothing effect provided by the present invention comprises, by weight percentage, 15-22% sodium tridecyl polyether sulfate, 2.5-5% glyceryl oleate and / or glyceryl laurate, 5-10% sunflower seed oil, 0.8-1.5% glycerophosphocholine, 0.8-1.6% kava leaf / root / stem extract, 3-6% sodium cocoyl methyl taurate taurate, 5-10% sodium lauroylamphoacetate, 5-8% cocamidopropyl betaine, 0.1-0.3% guar hydroxypropyltrimonium chloride, 3-5% acrylic acid (ester) copolymer, 0.5-1% preservative, and the balance is water.

[0032] The present invention also discloses a method for preparing a bath oil emulsion with a soothing effect, comprising the following steps:

[0033] Step 1: weigh and mix the components of the above-mentioned bath oil with soothing effect;

[0034] Step 2: Add water into a mixing pot, add guar hydroxypropyltrimonium chloride and stir evenly;

[0035] Step 3: Add sodium tridecyl alcohol polyether sulfate, sodium cocoyl methyl taurate taurate, sodium lauroyl amphoacetate, and cocamidopropyl betaine, raise the temperature to 75-85°C while stirring to dissolve and mix evenly, and keep warm for 10-20 minutes;

[0036] Step 4: Turn on the cooling water, stir and cool down to 45-50°C, add sunflower seed oil, glyceryl oleate and / or glyceryl laurate, stir evenly, and homogenize at a frequency of 35-50HZ for 5-8 minutes;

[0037] Step 5: Cool down to 40-45°C, add acrylic acid (ester) copolymer, glycerophosphorylcholine, kava leaf / root / stem extract and preservatives and mix well.

[0038] Beneficial Effects

[0039] Compared with the prior art, the present invention has at least the following advantages:

[0040] (1) The present invention discloses a bath gel with a soothing effect, which is compounded with sodium trideceth sulfate, sunflower seed oil, glycerophosphocholine, and kava leaf / root / stem extract to form micelles with high cleaning power that can stay on the surface of the skin and remove dirt such as sebum and microbial bacteria;

[0041] (2) The present invention can produce a significant synergistic effect of improving the soothing effect of the bath milk with soothing effect by compounding sodium trideceth sulfate, sunflower seed oil, glycerophosphocholine, and kava leaf / root / stem extract;

[0042] (3) The micelles formed by the specific amounts of sodium trideceth sulfate, sunflower seed oil, glycerophosphocholine, and kava leaf / root / stem extract of the present invention stay on the skin surface for a long time, so that the active ingredients with soothing effects can fully stay and penetrate into the skin to achieve excellent soothing effects, further improving the soothing effect of the shower gel with soothing effects. BRIEF DESCRIPTION OF THE DRAWINGS

[0043] The present invention is further described below in conjunction with the accompanying drawings and embodiments;

[0044] Figure 1 This is a chicken embryo test observation diagram of an application embodiment of the present invention. DETAILED DESCRIPTION

[0045] The present invention will be further described below in conjunction with the embodiments, but it does not constitute any limitation to the present invention. Any limited number of modifications made within the scope of the claims of the present invention are still within the scope of the claims of the present invention.

[0046] In order to explain the technical content of the present invention in detail, further description is given below in conjunction with the implementation modes.

[0047] In the following examples and comparative examples, the sunflower seed oil was purchased from Nanhai Oil Industry (Chiwan) Co., Ltd. (content 100wt%); the glycerophosphocholine solution was purchased from Guangzhou Jihui Biotechnology Co., Ltd., model PMB aqueous solution (composition of water 66wt%, butanediol 30wt%, glycerophosphocholine 4wt%); Kava pepper leaf / root / stem extract was purchased from AXIAFLUID KAVA EXTRACT UP produced by Guangzhou Zhongbo New Materials Co., Ltd. (its composition is water 54.45wt%, butanediol 44.55wt%, Kava pepper leaf / root / stem extract 1wt%); sodium tridecyl polyether sulfate was purchased from Sasol (China) Chemical Co., Ltd., model MARLINAT 337N (its ingredients are 65wt% sodium tridecyl polyether sulfate and 35wt% water); sodium cocoyl methyl taurate taurate was purchased from Zhangjiagang Great Chemical Co., Ltd.; sodium lauroyl amphoacetate was purchased from Foshan Hede New Materials Co., Ltd.; cocamidopropyl betaine was purchased from Guangzhou Xingye Technology Co., Ltd.; guar hydroxypropyltrimonium chloride was purchased from Guangzhou Hemiao Biotechnology Co., Ltd.; acrylic acid (ester) copolymer was purchased from Carbopol® Aqua SF-1 produced by Lubrizol Advanced Materials, Inc. Polymer; Glyceryl oleate was purchased from Guangzhou Hemiao Biotechnology Co., Ltd.; Glyceryl laurate was purchased from Guangzhou Hemiao Biotechnology Co., Ltd.; water-soluble 4-tert-butyl cyclohexanol was purchased from Guangzhou Junlang Biotechnology Co., Ltd. (its ingredients are 90wt% water and 10wt% 4-tert-butyl cyclohexanol); sodium lauryl polyether sulfate was purchased from Hunan Lichen Aowei Industrial Co., Ltd. (its ingredients are 70wt% sodium lauryl polyether sulfate and 30wt% water); olive oil was purchased from Guangzhou Ningyida Chemical Co., Ltd. (the content is 100wt%); lecithin was purchased from Guangzhou Rongdao Chemical Co., Ltd. (the content is 100wt%).

[0048] It should be noted that the technical solution protected by the present invention is not limited to the raw materials of the above-mentioned suppliers, and the technical solution of the present invention can be implemented by other commercially available raw materials.

[0049] In the following examples and comparative examples, unless otherwise specified, the parts and % refer to parts by weight and weight percentage, respectively; meanwhile, water is present as a solvent in the examples and comparative examples of the present invention.

[0050] In the following examples and comparative examples, the preparation method of the test bath oil emulsion is as follows:

[0051] Step 1: Weigh and mix according to the formula in Table 1;

[0052] Step 2: Add water to a stirring pot, add sodium tridecyl alcohol polyether sulfate or sodium laureth sulfate, stir while heating to 82±3℃ to dissolve and mix evenly, and keep warm for 15 minutes;

[0053] Step 3: Turn on the cooling water, stir and cool down to 48±2℃, add glyceryl oleate, sunflower seed oil or olive oil, stir evenly, and homogenize at a frequency of 45±5HZ for 8 minutes;

[0054] Step 4: Cool down to 42±2°C, add glycerophosphocholine or lecithin, Kava pepper leaf / root / stem extract or water-soluble 4-tert-butyl cyclohexanol and stir evenly.

[0055] It should be noted that, in the test bath oil, glyceryl oleate and water exist as an emulsifier and a solvent, respectively, and are not the soothing effect ingredients of the test bath oil.

[0056] Table 1 Test body wash formula

[0057] Sodium tridecyl alcohol polyether sulfate solution / % Sunflower seed oil / % Glycerophosphocholine solution / % Kava leaf / root / stem extract solution / % Sodium Laureth Sulfate / % olive oil / % Lecithin / % Water-soluble 4-tert-butyl cyclohexanol / % Glyceryl oleate / % water / % Example 1 22 8 1 0.8 0 0 0 0 2.5 Up to 100 Example 2 15 5 1.5 1 0 0 0 0 2.5 Up to 100 Example 3 20 10 0.8 1.6 0 0 0 0 2.5 Up to 100 Example 4 19 6 1.2 1.2 0 0 0 0 2.5 Up to 100 Comparative Example 1 0 6 1.2 1.2 0 0 0 0 2.5 Up to 100 Comparative Example 2 19 0 1.2 1.2 0 0 0 0 2.5 Up to 100 Comparative Example 3 19 6 0 2.4 0 0 0 0 2.5 Up to 100 Comparative Example 4 19 6 2.4 0 0 0 0 0 2.5 Up to 100 Comparative Example 5 19 0 0 0 0 0 0 0 2.5 Up to 100 Comparative Example 6 0 6 0 0 0 0 0 0 2.5 Up to 100 Comparative Example 7 0 6 1.2 1.2 19 0 0 0 2.5 Up to 100 Comparative Example 8 19 0 1.2 1.2 0 6 0 0 2.5 Up to 100 Comparative Example 9 19 6 0 1.2 0 0 0.048 0 2.5 Up to 100 Comparative Example 10 19 6 1.2 0 0 0 0 0.12 2.5 Up to 100

[0058] Efficacy Test

[0059] Soothing effect test

[0060] 1. Purpose and principle of relief test

[0061] According to the literature, hyaluronidase is a specific cleavage enzyme of hyaluronic acid, a participant in allergic reactions, and has a strong correlation with the release of histamine by mast cells. Whether the test sample has a soothing effect can be judged by the hyaluronidase inhibition rate. The higher the hyaluronidase inhibition rate, the stronger the soothing effect of the substance, and vice versa.

[0062] 2. Relevance of test methods

[0063] In this test, the hyaluronidase inhibition rate test results of the sample were compared with those of the negative control. If the inhibition rate of the test sample was higher than that of the negative control and there was a significant difference (P<0.05), it can be considered that the test sample has a certain soothing effect.

[0064] This test method is an in vitro method suitable for evaluating cosmetic products that claim to achieve soothing effects by inhibiting hyaluronidase.

[0065] 3. Test methods

[0066] Sample: Dilute the samples of Example and Comparative Example with pure water to a sample concentration of 2%;

[0067] Positive control (dipotassium glycyrrhizinate, purity>98%): diluted with water to a positive control concentration of 3%;

[0068] Negative control: pure water.

[0069] Set up a sample group, a sample background group, a solvent group and a solvent background group. Each group needs to have 3 parallels, and add different reagent solutions to each of the four groups.

[0070] Shake well, leave at room temperature for 30 min to develop color, and measure the absorbance at a wavelength of 528 nm using a UV spectrophotometer.

[0071] Calculation formula:

[0072] ;

[0073] Where: A is the absorbance of the reaction solution without sample; B is the absorbance of the reaction solution without sample and enzyme;

[0074] C is the absorbance of the reaction solution containing the sample and the enzyme; D is the absorbance of the reaction solution containing the sample but not the enzyme.

[0075] The statistical analysis software was SPSS, and the comparison of hyaluronidase inhibition rates between the test samples, positive controls, and negative controls was performed using an independent sample t-test. The above statistical analyses were all two-tailed tests, with a significance level of a = 0.05. P>0.05 indicated that there was no significant difference between the two groups; P<0.05 indicated that there was a significant difference between the two groups.

[0076] The shower gels of Examples 1-4 and Comparative Examples 1-10 were tested according to the above test method, and the results are shown in Table 2:

[0077] Table 2 Soothing efficacy results of the shower gels of Examples 1-4 and Comparative Examples 1-10

[0078] Hyaluronidase inhibition rate% P-value Example 1 23.035 ＜0.05 Example 2 24.201 ＜0.05 Example 3 27.626 ＜0.05 Example 4 25.051 ＜0.05 Comparative Example 1 16.781 ＜0.05 Comparative Example 2 7.237 ＜0.05 Comparative Example 3 5.556 ＜0.05 Comparative Example 4 7.331 ＜0.05 Comparative Example 5 -10.189 ＜0.05 Comparative Example 6 6.921 ＜0.05 Comparative Example 7 7.887 ＜0.05 Comparative Example 8 11.582 ＜0.05 Comparative Example 9 10.018 ＜0.05 Comparative Example 10 10.791 ＜0.05 Negative control -1.512 / Positive Control 59.070 ＜0.05

[0079] According to the results in Table 2, we can see that:

[0080] According to the data of Examples 1-4, the technical solution of the present invention has a higher hyaluronidase inhibition rate by compounding sodium trideceth sulfate, sunflower seed oil, glycerophosphocholine, and kava leaf / root / stem extract, which proves that the bath oil of the present invention has a significant soothing effect.

[0081] According to the data comparison of Example 4, Comparative Example 1 and Comparative Example 5, when Comparative Example 5 uses sodium tridecyl alcohol polyether sulfate alone, it has a certain skin irritation effect. Although Comparative Example 1 uses sunflower seed oil, glycerophosphocholine, and kava pepper leaf / root / stem extract to compound, although there is a certain hyaluronidase inhibition rate, according to the performance of Comparative Example 5, theoretically, when compounded with sodium tridecyl alcohol polyether sulfate, the hyaluronidase inhibition rate should be reduced; However, the present invention finds that the hyaluronidase inhibition rate is greatly improved by compounding sodium tridecyl alcohol polyether sulfate, sunflower seed oil, glycerophosphocholine, and kava pepper leaf / root / stem extract, indicating that the compounding of sodium tridecyl alcohol polyether sulfate, sunflower seed oil, glycerophosphocholine, and kava pepper leaf / root / stem extract produces a synergistic effect of enhancing the soothing effect; and since Comparative Example 1 lacks sodium tridecyl alcohol polyether sulfate, the formula viscosity is too low, and high-temperature stratification and demulsification occur, the stability of the actual product is very low, and it is difficult to industrialize.

[0082] Similarly, according to the data of Example 4 and Comparative Examples 2 and 6, theoretically, when sodium tridecyl sulfate, sunflower seed oil, glycerophosphocholine, and kava leaf / root / stem extract are compounded, the hyaluronidase inhibition rate that can be achieved should be the superposition of the effects of Comparative Examples 2 and 6, but compared with the superposition of the effects of Comparative Examples 2 and 6, the hyaluronidase inhibition rate of Example 4 is significantly improved, further verifying that the compounding of sodium tridecyl sulfate, sunflower seed oil, glycerophosphocholine, and kava leaf / root / stem extract produces a synergistic effect of enhancing the soothing effect.

[0083] According to the data comparison between Example 4 and Comparative Example 3 and Comparative Example 4, it can be seen that the synergistic effect of the present invention is based on the combination of sodium tridecyl polyether sulfate, sunflower seed oil, glycerophosphocholine, and Piper methysticum leaf / root / stem extract. In the absence of glycerophosphocholine and Piper methysticum leaf / root / stem extract, Comparative Example 3 and Comparative Example 4, even if the dosage is increased to other components, the hyaluronidase inhibition rate will be greatly reduced; it should be noted that the amount of glycerophosphocholine is added to the Piper methysticum leaf / root / stem extract in Comparative Example 3, and the amount of Piper methysticum leaf / root / stem extract is added to glycerophosphocholine in Comparative Example 4 because both are water-soluble substances, while sunflower seed oil is an oil-soluble substance, and sodium tridecyl polyether sulfate is a surfactant.

[0084] According to the data comparison of Example 4 and Comparative Example 7, combined with the data of Comparative Examples 2 and 6, it can be seen that normally, on the basis of the compounding of the soothing components of sunflower seed oil, glycerophosphocholine and Piper methysticum leaf / root / stem extract, the addition of a surfactant will lead to a decrease in the soothing effect and a decrease in the hyaluronidase inhibition rate. However, the technical solution of the present invention has instead shown a significant increase, indicating that the compounding of sodium tridecyl polyether sulfate with sunflower seed oil, glycerophosphocholine and Piper methysticum leaf / root / stem extract produces a synergistic effect. It is speculated that the possible reason is that sodium tridecyl polyether sulfate, as the main surfactant, improves the properties of the micelle through emulsification with sunflower seed oil, so that the glycerophosphocholine and Piper methysticum leaf / root / stem extract components therein can be better attached to the micelle, thereby making the soothing active ingredients more prominent.

[0085] In addition, the micelles formed by the technical solution of the present invention have a relatively large diameter and a surface charge closer to neutrality, which improves the penetration kinetics of the micelles through the stratum corneum and the ocular mucosa. Therefore, in actual skin care applications, the irritation is lower and the soothing effect is better.

[0086] According to the data comparison of Example 4 and Comparative Examples 8-10, it can be seen that the synergistic effect of the combination of sodium tridecyl polyether sulfate and sunflower seed oil, glycerophosphocholine, and kava pepper leaf / root / stem extract is indispensable. The technical solution of using olive oil instead of sunflower seed oil, lecithin instead of glycerophosphocholine, and water-soluble 4-tert-butyl cyclohexanol instead of kava pepper leaf / root / stem extract cannot produce a synergistic effect, but only exerts the soothing effect it should have.

[0087] Application Examples

[0088] The bath oil emulsion was prepared according to the formula in Table 3. The preparation method is as follows:

[0089] Step 1: weigh and proportion the components in the bath oil in Table 3;

[0090] Step 2: Add water into a mixing pot, add guar hydroxypropyltrimonium chloride and stir evenly;

[0091] Step 3: Add sodium tridecyl alcohol polyether sulfate, sodium cocoyl methyl taurate taurate, sodium lauroyl amphoacetate, and cocamidopropyl betaine, raise the temperature to 82±3℃ while stirring to dissolve and mix evenly, and keep warm for 20 minutes;

[0092] Step 4: Turn on the cooling water, stir and cool down to 48±2℃, add glyceryl oleate, glyceryl laurate, and sunflower seed oil, stir evenly, and homogenize at a frequency of 45±5HZ for 8 minutes;

[0093] Step 5: Cool down to 42±2℃, add acrylic acid (ester) copolymer, glycerophosphorylcholine, kava leaf / root / stem extract, phenoxyethanol, and sodium benzoate and mix well.

[0094] Table 3 Application of bath oil formula

[0095] Usage% water Up to 100 Sodium Trideceth Sulfate 20 Sunflower Seed Oil 10 Glycerophosphocholine 0.8 Kava Leaf / Root / Stem Extract 0.8 Sodium Cocoyl Methyl Taurate 3 Sodium lauroamphoacetate 8 Cocamidopropyl Betaine 5 Guar Hydroxypropyltrimonium Chloride 0.2 Glyceryl Oleate 2.5 Glyceryl Laurate 2 Phenoxyethanol 0.5 Sodium Benzoate 0.3 Acrylic acid (ester) copolymer 4

[0096] Effect test

[0097] 1. Soothing effect test

[0098] The application example was tested according to the above-mentioned soothing efficacy test, and the hyaluronidase inhibition rate obtained by the test was 25.626%.

[0099] 2. Irritation test

[0100] 1. Purpose and principle of irritation test

[0101] Refer to "SN / T 2329-2009 Chicken chorioallantoic membrane test for eye irritation and corrosion of cosmetics";

[0102] The chorioallantoic membrane (CAM) is a respiratory membrane that surrounds the chicken embryo. The chicken embryo chorioallantoic membrane test utilizes the characteristics of the intact, clear and transparent vascular system of the chorioallantoic membrane of the mid-stage incubated chicken embryo. A certain amount of the test substance is directly exposed to the chicken embryo chorioallantoic membrane. After a period of action, the toxic effect indicators of the chorioallantoic membrane (such as changes in bleeding, coagulation and vascular lysis) are observed. These indicators reflect the changes in the morphological structure, color and permeability of the blood vessels and vascular networks, as well as the phenomena such as the denaturation of the chorioallantoic membrane protein and its degree of damage. Then a score is obtained by combining them to evaluate the eye irritation of the test substance. The purpose of this experiment is to test the ability of the test substance to cause toxic changes in the chicken embryo chorioallantoic membrane. The standard describes the elements and processes for evaluating the potential irritation of the substance being evaluated.

[0103] 2. Relevance of test methods

[0104] The ability of the test substance to cause toxic changes in the chicken embryo chorioallantoic membrane was tested to evaluate the potential irritation of the test substance.

[0105] 3. Test methods

[0106] (1) Place the eggs in an incubator and incubate for 9 days at a temperature of 37.5°C + 0.5°C and a relative humidity of 55% to 70%;

[0107] (2) Use a pencil to draw the position of the egg air chamber, and at the same time observe whether the chicken embryo is well developed and whether the blood vessels grow normally, determine the number of eggs that can be used for testing, and allocate the eggs required for the sample to be tested;

[0108] (3) During the test, the eggshell part marked along the drawn air chamber mark was removed with a tool, physiological saline was added with a pipette to moisten the egg membrane, the sodium chloride solution was poured out, and the inner membrane was carefully removed with forceps to ensure that the blood vessels were not damaged. The chicken embryo was observed to have no obvious bleeding or turbidity, which was then judged to be suitable for the test;

[0109] (4) Experiment using the reaction time method. Use a pipette to draw 300uL of sample and add it to the CAM membrane. Start timing and take a photo to record the state just after the sample is added. Observe the changes in the blood vessels in the circle. When bleeding, vascular lysis, coagulation and other state changes occur, record the time and take a photo to record the state of the chicken embryo. 5 minutes after adding the sample, take a photo to record the state of the chicken embryo and end the observation.

[0110] (5) Observation of results

[0111] Bleeding: refers to the outflow of blood from the blood vessels or capillaries of the CAM.

[0112] Coagulation: refers to the denaturation of proteins inside and outside blood vessels, usually seen as enlarged blood vessels, excluding capillaries. Thrombosis: refers to intravascular coagulation, interruption of blood flow in blood vessels caused by different reasons, changes in blood flow, and the appearance of dark coagulation spots inside the blood vessels. Extravascular coagulation: manifested as dark coagulation spots outside blood vessels, and can also be manifested as turbidity, the appearance of all or part of the membrane, similar to milky white gauze.

[0113] Vascular lysis: refers to the disappearance of blood vessels on the CAM membrane.

[0114] (6) Calculation of irritation score

[0115] For tests conducted using the reaction time method, the irritation score (IS) was calculated according to the following formula, with the result rounded to two decimal places;

[0116] ;

[0117] Where:

[0118] The average time to the onset of bleeding observed on the H-CAM membrane, in seconds (s);

[0119] The average time to the onset of vascular melting observed on the L-CAM membrane, in seconds (s);

[0120] The average time for the onset of coagulation to be observed on the C-CAM membrane, in seconds (s);

[0121] Note: If H, L, or C has the corresponding phenomenon, fill in the number of seconds when it occurs. If it does not occur, fill in 301.

[0122] The shower gel used in the application example was tested according to the above test method, and the irritation score was 2.41. Figure 1It is a test observation diagram of the application embodiment.

[0123] The embodiments presented herein are only embodiments selected according to the combination of all possible embodiments. The appended claims should not be limited by the embodiments describing the present invention. Some numerical ranges used in the claims include sub-ranges therein, and the changes in these ranges should also be covered by the appended claims.

Claims

1. A bath oil with soothing effect, characterized in that: The invention is composed of the following components by weight percentage: 15-22% sodium tridecyl alcohol polyether sulfate solution, 5-10% sunflower seed oil, 0.8-1.5% glycerophosphocholine solution, 0.8-1.6% kava pepper leaf / root / stem extract solution, 3-6% sodium cocoyl methyl taurate taurate, 5-10% sodium lauroyl amphoacetate, 5-8% cocamidopropyl betaine, 0.1-0.3% guar hydroxypropyltrimonium chloride, 3-5% acrylic acid (ester) copolymer, 2.5-5% glyceryl oleate and / or glyceryl laurate, and the balance is water; The sodium tridecyl alcohol polyether sulfate solution contains 65wt% of sodium tridecyl alcohol polyether sulfate, and the rest is solvent; the glycerophosphocholine solution contains 4wt% of glycerophosphocholine, and the rest is solvent; the Piper mesenteriae leaf / root / stem extract solution contains 1wt% of Piper mesenteriae leaf / root / stem extract, and the rest is solvent.

2. A method for preparing a bath oil having a soothing effect, characterized in that: The steps include: Step 1: weigh and proportion the components in the bath oil with soothing effect as claimed in claim 1; Step 2: Add water into a mixing pot, add guar hydroxypropyltrimonium chloride and stir evenly; Step 3: Add sodium tridecyl alcohol polyether sulfate solution, sodium cocoyl methyl taurate taurate, sodium lauroyl amphoacetate, and cocamidopropyl betaine, heat to 75-85°C while stirring to dissolve and mix evenly, and keep warm for 10-20 minutes; Step 4: Turn on the cooling water, stir and cool down to 45-50°C, add sunflower seed oil, glyceryl oleate and / or glyceryl laurate, stir evenly, and homogenize at a frequency of 35-50HZ for 5-8 minutes; Step 5: Cool down to 40-45°C, add acrylic acid (ester) copolymer, glycerophosphorylcholine solution, and kava leaf / root / stem extract solution and stir evenly.

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