A cell separation and extraction device for leukemia testing

Abstract

The present invention relates to the technical field of cell separation and extraction, and proposes a cell separation and extraction device for leukemia testing, comprising a first connecting tube, a connecting component installed on the first connecting tube, a second connecting tube slidably installed in the connecting component, a connecting component installed on the side of the second connecting tube, a third connecting tube slidably installed above the second connecting tube, a lap rod installed on the third connecting tube, a first cross bar fixedly connected to the bottom of the lap rod, a second connecting block fixedly arranged in the middle of the first cross bar, and a first traction steel rope fixedly connected to the second connecting block. Through the above technical scheme, the problem that the existing cell separation and extraction device cannot automatically increase the aperture of the upper half of the sieve plate through hole in the tube body and automatically reduce the aperture of the lower half through the bending structure, and cannot perform extraction work from the tube body while maintaining closure is solved.

Description

Technical Field

[0001] The present invention relates to the technical field of cell separation and extraction, and in particular to a cell separation and extraction device for leukemia testing. Background Art

[0002] Leukemia is a malignant tumor originating from the hematopoietic system, which is mainly manifested by the proliferation of abnormal white blood cells, affecting the production of normal blood cells. Early diagnosis and accurate typing are crucial to the selection of treatment options and prognosis assessment for leukemia. In clinical practice, cell separation and extraction technology has become an important part of leukemia testing, and existing cell separation and extraction devices still have some shortcomings.

[0003] The invention patent with publication number CN105132278B discloses a cell separation tube with a sieve plate for separating and extracting PBMC, including a tube cover, a tube body, an isolation sieve plate and a separation liquid, wherein the tube cover is coaxially threaded and sealed on the top of the tube body, and the lower part of the tube body is coaxially sealed with the inner wall of the tube body to install the isolation sieve plate, and the isolation sieve plate is evenly spaced and provided with a number of sieve holes, and the bottom of the tube body below the isolation sieve plate is encapsulated with the cell separation liquid. The isolation sieve plate of the separation tube can quickly add the blood sample to the top of the isolation sieve plate, and can prevent the blood sample from mixing with the separation liquid below the sieve plate, and the isolation sieve plate also effectively prevents the separation liquid injected below the isolation sieve plate from "backflowing" to the top of the isolation sieve plate of the separation tube when the separation tube is inverted, transported, bumped, vibrated or collided, thereby ensuring that the cell separation liquid is always in the separation tube below the isolation sieve plate, thereby making the cell extraction operation more reliable and convenient. Although the above-mentioned device can realize the screening function, when in use, it is not possible to automatically increase the aperture of the upper half of the sieve plate through hole in the tube body and automatically reduce the aperture of the lower half through the bending structure, which is not conducive to subsequent cell extraction work, and the existing separation and extraction device cannot perform extraction work from the tube body while maintaining closure. Summary of the invention

[0004] The present invention provides a cell separation and extraction device for leukemia testing, which solves the problem that the existing cell separation and extraction device cannot automatically increase the aperture of the upper half of the sieve plate through hole in the tube body and automatically reduce the aperture of the lower half through the bending structure, and cannot perform extraction work from the tube body while maintaining closure.

[0005] The technical solution of the present invention is as follows:

[0006] A cell separation and extraction device for leukemia testing comprises a first connecting tube, a connecting assembly is installed on the first connecting tube, a second connecting tube is slidably installed in the connecting assembly, a connecting assembly is installed on the side of the second connecting tube, a third connecting tube is slidably installed above the second connecting tube, a lap rod is installed on the third connecting tube, a first cross bar is fixedly connected to the bottom of the lap rod, a second connecting block is fixedly arranged in the middle of the first cross bar, a first traction steel rope is fixedly connected to the second connecting block, a second connecting tube is fixedly connected to the second cross bar, and the second cross bar is fixedly connected to the second cross bar. A guide wheel is rotatably installed on the top, the first traction steel rope is connected to the separation component through the guidance of the guide wheel, the separation component is installed in the second connecting tube, a top cover is installed on the top of the third connecting tube, an adjustment plate is slidably installed in the top cover, an outer bushing is fixedly connected on the adjustment plate, a ball shaft is rotatably installed in the outer bushing and the adjustment plate, an extraction tube is arranged in the ball shaft, a second slide plate is arranged in the extraction tube, a second traction steel rope is fixedly connected to the second slide plate, a negative pressure assembly is arranged on the top of the second traction steel rope, and a window is installed on the second connecting tube.

[0007] As a preferred solution of the present invention, the connecting component includes a first connecting tube fixedly connected to the first connecting tube, a first baffle fixedly connected to the first connecting tube, a second connecting tube rotatably mounted on the first connecting tube, and a second baffle fixedly connected to the second connecting tube.

[0008] As a preferred solution of the present invention, a protrusion is fixedly connected to the second connecting tube, and a sliding groove for the protrusion to move is provided in the first connecting tube.

[0009] As a preferred solution of the present invention, the connecting assembly includes a slider slidably mounted on the second connecting tube, the slider is fixedly connected to a first slider, the first slider is fixedly provided with a first connecting block, the first connecting block is fixedly provided with a connecting plate, the second connecting tube is fixedly provided with a rubber plate, and the first slider and the connecting plate are abutted against each other.

[0010] As a preferred solution of the present invention, a rubber pressure plate is fixedly connected to the third connecting tube, and the rubber pressure plate is symmetrically distributed on both sides of the second connecting tube and the third connecting tube. The third connecting tube, the lap rod and the first cross bar are fixedly connected to form an integral structure.

[0011] As a preferred solution of the present invention, the separation assembly includes a guide rod fixedly connected to the second connecting tube, an outer frame is slidably installed on the outer side of the guide rod, a sieve plate is fixedly arranged in the outer frame, sieve holes and slits are arranged on the sieve plate, a third connecting block is fixedly arranged in the middle of the sieve plate, and the third connecting block is connected to the bottom of the first traction steel rope.

[0012] As a preferred solution of the present invention, the outer frame and the sieve plate are both made of rubber material, the thickness of the outer frame and the sieve plate are the same, the depth of the slit is less than the thickness of the sieve plate, and the position of each row of sieve holes corresponds to the position of each slit.

[0013] As a preferred solution of the present invention, the outer wall of the adjustment plate and the inner wall of the top cover are in contact with each other, the extraction tube forms a rotating structure with the adjustment plate through the ball shaft, and the ball shaft forms a sliding structure with the adjustment plate and the top cover.

[0014] As a preferred solution of the present invention, the negative pressure assembly includes a sliding sleeve slidably installed on the outside of the extraction tube, the sliding sleeve is fixedly connected to a first connecting rod, the first connecting rod is fixedly connected to a connecting ring, the connecting ring is fixedly provided with an extension rod, the bottom of the extension rod is connected to the second traction steel rope, the extraction tube is fixedly provided with a third cross bar, the second traction steel rope is connected to the second slide plate through the guidance of the third cross bar, the bottom of the second slide plate is fixedly connected to an elastic rope, the bottom of the elastic rope is fixedly connected to a convex ring, and the convex ring and the extraction tube are fixedly connected.

[0015] As a preferred solution of the present invention, the elastic rope is evenly distributed along the circumference of the convex ring, the second slide plate and the extraction tube are slidably connected, and the second slide plate forms a lifting structure with the extraction tube through the second traction steel rope, extension rod and third cross bar.

[0016] The working principle and beneficial effects of the present invention are:

[0017] 1. The device is provided with a separation component, which can abut against the connection component during the upward movement, so that the sieve plate on the separation component is bent. During the bending of the sieve plate, the slit gap on the sieve plate is in a state of decreasing width from top to bottom, so that the sieve holes on the sieve plate also maintain a trend of decreasing diameter from top to bottom, so that the inner cells of the corresponding sieve holes can be extracted conveniently later, which solves the problem that the existing cell separation and extraction device cannot automatically increase the aperture of the upper half of the sieve plate through hole in the tube body and automatically reduce the aperture of the lower half through the bending structure. The device has the advantage of being more convenient to use.

[0018] 2. Through the second slide, the second traction steel rope and the negative pressure assembly on the device, the angle and position of the extraction tube are changed through the ball shaft and the adjustment plate, so as to accurately extract the blood sample in the corresponding sieve hole. After moving the bottom of the extraction tube to the sieve hole at the corresponding position, the sliding sleeve is driven to move downward by pressing the connecting ring. When the sliding sleeve moves downward, the second traction steel rope will be pulled by the extension rod, and the second traction steel rope will drive the second slide to move upward again. When the second slide moves upward, negative pressure will be generated in the lower half of the extraction tube, thereby adsorbing the liquid in the sieve hole to realize the cell extraction function. With the window, the device can realize the cell extraction function without opening the top cover, which solves the problem that the existing cell separation and extraction device cannot extract from the tube body while keeping it closed. The device has the advantage of being safer to use.

[0019] 3. The device is provided with a connecting component, which can manually press the connecting plate on the connecting component so that the rubber plate maintains different degrees of pressure, thereby changing the expansion degree of the upper part of the sieve hole when the sieve plate moves upward, so as to adapt to different needs for cell extraction and enhance the scope of application of the device. When extracting cells, the device can change the position of the ball shaft through the adjustment plate and change the angle of the extraction tube through the ball shaft, thereby realizing the function of precise cell extraction.

[0020] 4. The device is provided with a first connecting tube and a second connecting tube. The initial position of the first connecting tube on the second connecting tube can be adjusted as needed, thereby changing the position of the connecting component when the device is in use. When the connecting component is located above the sieve plate, separation and extraction can be performed from bottom to top. When the connecting component is located below the sieve plate, separation and extraction can be performed from bottom to top. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0022] Figure 1 It is a schematic diagram of the overall structure of a cell separation and extraction device for leukemia testing of the present invention;

[0023] Figure 2 yes Figure 1 A magnified schematic diagram of the structure at center A;

[0024] Figure 3 It is a schematic diagram of the connection structure between the second connecting pipe and the first connecting pipe of the present invention;

[0025] Figure 4 This is a schematic diagram of the split structure of the first connecting pipe and the second connecting pipe of the present invention;

[0026] Figure 5 is a schematic diagram of the internal structure of the second connecting pipe of the present invention;

[0027] Figure 6yes Figure 5 A magnified schematic diagram of the structure at B in the middle;

[0028] Figure 7 yes Figure 5 A magnified schematic diagram of the structure at C in the middle;

[0029] Figure 8 yes Figure 5 A magnified schematic diagram of the structure at D in the middle;

[0030] Fig. 9 It is a schematic diagram of the connection structure between the outer frame and the guide rod of the present invention;

[0031] Fig.10 It is a schematic diagram of the connection structure between the top cover and the adjustment plate of the present invention;

[0032] Fig.11 yes Fig.10 A magnified schematic diagram of the structure at E in the middle;

[0033] Fig.12 yes Fig.10 A magnified schematic diagram of the structure at F in the middle.

[0034] Reference numerals: 1, first connecting pipe; 2, connecting assembly; 201, first connecting pipe; 202, first baffle; 203, second connecting pipe; 204, second baffle; 3, second connecting pipe; 4, protrusion; 5, slide groove; 6, connecting assembly; 601, slider; 602, first slide plate; 603, first connecting block; 604, connecting plate; 605, rubber plate; 7, third connecting pipe; 8, lap rod; 9, first cross bar; 10, second connecting block; 11, first traction steel rope; 12, second cross bar; 13, guide wheel; 14, separation assembly; 1401, outer frame; 1402, sieve plate; 1403, sieve hole; 1404, slit; 1405, third connecting block; 1406, guide rod; 15, top cover; 16, adjustment plate; 17, outer bushing; 18, ball shaft; 19, extraction tube; 20, second slide plate; 21, second traction steel rope; 22, negative pressure assembly; 2201, sliding sleeve; 2202, first connecting rod; 2203, connecting ring; 2204, extension rod; 2205, third cross bar; 2206, elastic rope; 2207, convex ring; 23, rubber pressure plate; 24, first magnetic block; 25, second magnetic block; 26, window. DETAILED DESCRIPTION

[0035] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0036] Example 1: Figure 1-Figure 12 As shown, this embodiment proposes a cell separation and extraction device for leukemia testing, comprising a first connecting tube 1, on which a connecting component 2 is installed, the connecting component 2 is used to inject a sample into the interior of the device, a second connecting tube 3 is slidably installed in the connecting component 2, a connecting component 6 is installed on the side of the second connecting tube 3, the connecting component 6 can adjust its own squeezing degree so as to subsequently adjust the size of the cell extraction space, a third connecting tube 7 is slidably installed above the second connecting tube 3, a lap rod 8 is installed on the third connecting tube 7, a first cross bar 9 is fixedly connected to the bottom of the lap rod 8, a second connecting block 10 is fixedly arranged in the middle of the first cross bar 9, a first traction steel rope 11 is fixedly connected to the second connecting block 10, a second cross bar 12 is fixedly connected to the second connecting tube 3, a guide wheel 13 is rotatably installed on the second cross bar 12, the first traction steel rope 11 is guided by the guide wheel 13 and connected to the separation component 14, the device can press down the third connecting tube 7, thereby increasing the pressure in the device, so that the leukemia test sample can be passed through the separation component 14 The separation component 14 is installed in the second connecting pipe 3. By adjusting the position of the first connecting pipe 1 on the second connecting pipe 3, the position of the connecting component 2 is changed. When the connecting component 2 is located above the separating component 14, the separation and extraction can be performed from top to bottom. When the connecting component 2 is located below the separating component 14, the separation and extraction can be performed from bottom to top. A top cover 15 is installed on the top of the third connecting pipe 7. When the third connecting pipe 7 moves downward, it will be pulled. An adjusting plate 16 is slidably installed in the top cover 15. The adjusting plate 16 is fixed An outer bushing 17 is connected, and a ball shaft 18 is rotatably installed in the outer bushing 17 and the adjustment plate 16. An extraction tube 19 is arranged in the ball shaft 18, and a second slide plate 20 is arranged in the extraction tube 19. A second traction steel rope 21 is fixedly connected to the second slide plate 20, and a negative pressure component 22 is arranged on the top of the second traction steel rope 21. A window 26 is installed on the second connecting tube 3. The negative pressure component 22 can move the second slide plate 20 in the extraction tube 19 upward after the extraction tube 19 moves to the extraction position, thereby generating negative pressure to realize the extraction function.

[0037] Example 2: Figure 1-Figure 12 As shown, based on the same concept as the above-mentioned embodiment 1, this embodiment also proposes a cell separation and extraction device for leukemia testing.

[0038] In this embodiment, the connecting component 2 includes a first connecting tube 201 fixedly connected to the first connecting tube 1, a first baffle 202 fixedly connected to the first connecting tube 201, a second connecting tube 203 rotatably mounted on the first connecting tube 1, a second baffle 204 fixedly connected to the second connecting tube 203, the second connecting tube 203 can rotate on the first connecting tube 201, when the second baffle 204 overlaps with the first baffle 202, the blood sample can be injected into the device, and when the first baffle 202 and the second baffle 204 are intertwined with each other, the device can remain closed.

[0039] In this embodiment, a protrusion 4 is fixedly connected to the second connecting tube 3, and a slide groove 5 for the protrusion 4 to move is provided in the first connecting tube 1. The protrusion 4 and the slide groove 5 allow the first connecting tube 1 to slide stably on the second connecting tube 3 to subsequently change the injection position of the blood sample.

[0040] In this embodiment, the connecting component 6 includes a slider 601 slidably mounted on the second connecting tube 3, a first slider 602 is fixedly connected to the slider 601, a first connecting block 603 is fixedly arranged on the first slider 602, a connecting plate 604 is fixedly arranged on the first connecting block 603, a rubber plate 605 is fixedly arranged on the second connecting tube 3, the first slider 602 and the connecting plate 604 are abutted against each other, the first slider 602 can slide on the second connecting tube 3 through the slider 601, and the extrusion state of the rubber plate 605 can be changed by pressing the connecting plate 604 on the first connecting block 603, so as to facilitate the subsequent adjustment of the separation size when separating cells.

[0041] In this embodiment, a rubber pressure plate 23 is fixedly connected to the third connecting tube 7, and the rubber pressure plate 23 is symmetrically distributed on the left and right sides of the second connecting tube 3 and the third connecting tube 7. The third connecting tube 7, the lap rod 8 and the first cross bar 9 are fixedly connected as an integral structure to ensure the overall stability of the device. The rubber pressure plate 23 can make the third connecting tube 7 slide when not pressed. After pressing the rubber pressure plate 23, the rubber pressure plate 23 can drive the second connecting tube 3 to move downward synchronously. A first magnetic block 24 is fixedly connected to the top cover 15, and a second magnetic block 25 is adsorbed under the first magnetic block 24. The third connecting tube 7 and the second magnetic block 25 are fixedly connected, and the first magnetic block 24 and the second magnetic block 25 keep the top cover 15 closed.

[0042] In this embodiment, the separation component 14 includes a guide rod 1406 fixedly connected to the second connecting tube 3, an outer frame 1401 is slidably installed on the outer side of the guide rod 1406, a sieve plate 1402 is fixedly arranged in the outer frame 1401, sieve holes 1403 and slits 1404 are arranged on the sieve plate 1402, a third connecting block 1405 is fixedly arranged in the middle of the sieve plate 1402, the third connecting block 1405 is connected to the bottom of the first traction steel rope 11, the outer frame 1401 is moved up and down by the guide rod 1406 on the device, and the third connecting block 1405 enables the sieve plate 1402 to be stably pulled upward.

[0043] In this embodiment, the outer frame 1401 and the sieve plate 1402 are both made of rubber material, the thickness of the outer frame 1401 and the sieve plate 1402 is the same, the depth of the slit 1404 is less than the thickness of the sieve plate 1402, and the position of each row of sieve holes 1403 corresponds to the position of each slit 1404. When the outer frame 1401 and the sieve plate 1402 are pulled upward, the two sides of the outer frame 1401 will be supported, so that the middle of the sieve plate 1402 is lifted up. At this time, the sieve holes 1403 tend to be larger at the top and smaller at the bottom, which is convenient for subsequent cell extraction.

[0044] In this embodiment, the outer wall of the adjustment plate 16 and the inner wall of the top cover 15 are in contact with each other, the extraction tube 19 forms a rotating structure with the adjustment plate 16 through the ball shaft 18, and the ball shaft 18 forms a sliding structure with the adjustment plate 16 and the top cover 15. The ball shaft 18 can slide on the top cover 15 along with the adjustment plate 16, thereby changing the extraction position, and the ball shaft 18 can rotate in the adjustment plate 16 to subsequently adjust the extraction angle.

[0045] In this embodiment, the negative pressure assembly 22 includes a sliding sleeve 2201 slidably mounted on the outside of the extraction tube 19, the sliding sleeve 2201 is fixedly connected to a first connecting rod 2202, the first connecting rod 2202 is fixedly connected to a connecting ring 2203, the connecting ring 2203 is fixedly provided with an extension rod 2204, the bottom of the extension rod 2204 is connected to the second traction steel rope 21, the extraction tube 19 is fixedly provided with a third cross bar 2205, the second traction steel rope 21 is connected to the second slide plate 20 through the third cross bar 2205, the bottom of the second slide plate 20 is fixedly connected to an elastic rope 2206, the bottom of the elastic rope 2206 is fixedly connected to a convex ring 2207, the convex ring 2207 and the extraction tube 19 are fixedly connected, as shown in FIG. Figure 10-12As shown, when the connecting ring 2203 is pressed downward, the second traction steel rope 21 will be pulled through the extension rod 2204 first, and the second traction steel rope 21 will pull the second slide plate 20 to move upward, and the elastic rope 2206 will be stretched. After the elastic rope 2206 is stretched to a certain extent, the second slide plate 20 will no longer move upward, and the downward pressure of the third cross bar 2205 by the second traction steel rope 21 will cause the extraction tube 19 to move downward. When the bottom of the extraction tube 19 moves to the extraction area, the resistance to further downward movement of the extraction tube 19 increases. At this time, the elastic rope 2206 is stretched again, so that the connecting ring 2203 moves downward again, and the sliding sleeve 2201 slides to the bottom of the extraction tube 19. The second traction steel rope 21 pulls the second slide plate 20 to move upward, so that negative pressure is generated in the extraction tube 19 located below the second slide plate 20, thereby realizing the extraction function.

[0046] In this embodiment, the elastic rope 2206 is evenly distributed along the circumference of the convex ring 2207, and the second slide 20 and the extraction tube 19 are slidably connected to ensure that the tension on the second slide 20 is uniform when the device is in use. The second slide 20 forms a lifting structure with the extraction tube 19 through the second traction steel rope 21, the extension rod 2204 and the third cross bar 2205. The lifting structure on the device enables the extraction tube 19 to use negative pressure to extract cells after moving to a suitable area.

[0047] Specifically, the present invention is a cell separation and extraction device for leukemia testing, first, as Figure 1-Figure 9As shown, when in use, the position of the first connecting tube 1 on the second connecting tube 3 is adjusted by the protrusion 4 and the slide groove 5. When the connecting component 2 is located above the sieve plate 1402 in the second connecting tube 3, separation and extraction can be performed from top to bottom. When the connecting component 2 is located below the sieve plate 1402 in the second connecting tube 3, separation and extraction can be performed from bottom to top. When in use, by rotating the second connecting tube 203, when the second baffle 204 overlaps with the first baffle 202, the opening on the first connecting tube 1 is opened, and a blood sample can be injected into the device. When separating, by sliding the first connecting tube 1 upward or moving the third connecting tube 7 downward, when it is necessary to slide the first connecting tube 1 upward, the rubber pressing plate 23 can be pressed and the first connecting tube 1 can be moved upward, so that the rubber pressing plate 23 can press the second connecting tube 3, so that the second connecting tube 3 and the third connecting tube 7 will not slip. After the air pressure in the device increases, the blood sample can be separated through the sieve plate 1402 on the separation component 14. When extracting after separation, the third connecting tube 7 can be moved downward. As the third connecting tube 7 moves downward, the first cross bar 9 under the lap rod 8 can pull the first traction steel rope 11 on the guide wheel 13 through the second connecting block 10. The first traction steel rope 11 will pull the third connecting block 1405 to move upward. When the third connecting block 1405 moves upward, it will drive the outer frame 1401 and the sieve plate 1402 on the separation component 14 to rise. After the sieve plate 1402 moves up to a certain position, the outer frame 1401 will abut the protruding rubber plate 605, and the middle of the sieve plate 1402 will be convex, so that the width of the slit 1404 is larger at the top and smaller at the bottom, and the diameter of the sieve hole 1403 is larger at the top and smaller at the bottom. At this time, the extraction work after separation can be carried out. When in use, the connecting plate 604 on the first connecting block 603 can be pressed to allow the first slide plate 602 to slide on the second connecting tube 3 through the slider 601, and the rubber plate 605 can be squeezed by the first slide plate 602 to change the distance between the rubber plates 605 on both sides of the device, so that when the sieve plate 1402 moves up to a certain position, the opening size of the slit 1404 on the sieve plate 1402 changes, thereby adjusting the separation size when separating cells.

[0048] like Figure 1-Figure 3 and Figure 5-Figure 12As shown, during extraction, the positions of the outer sleeve 17 and the ball shaft 18 on the top cover 15 can be changed by adjusting the plate 16, and then the extraction tube 19 can be changed in angle by the ball shaft 18, and the bottom of the extraction tube 19 can be accurately moved to the sieve hole 1403 at the corresponding position in cooperation with the viewing window 26. Press down the connecting ring 2203, the connecting ring 2203 will pull the second traction steel rope 21 through the extension rod 2204, the second traction steel rope 21 will pull the second slide plate 20 to move upward, and the elastic rope 2206 will be stretched. After the elastic rope 2206 is stretched to a certain extent, the second slide plate 20 will no longer move upward, and the downward pressure of the third cross bar 2205 by the second traction steel rope 21 will cause the extraction tube 19 to move downward. When the bottom of the extraction tube 19 moves to the extraction area, the resistance to further downward movement of the extraction tube 19 increases. At this time, the elastic rope 2206 will be stretched again, causing the connecting ring 2203 to move downward again, and the sliding sleeve 2201 slides to the bottom of the extraction tube 19. The second traction steel rope 21 pulls the second slide plate 20 to move upward, so that negative pressure is generated in the extraction tube 19 located below the second slide plate 20, so that the device can realize the function of moving the extraction tube 19 to the extraction position and then using negative pressure for extraction in sequence only by pressing down the connecting ring 2203.

[0049] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A cell separation and extraction device for leukemia testing, comprising a first connecting tube (1), characterized in that: The first connecting tube (1) is provided with a connecting assembly (2), a second connecting tube (3) is slidably installed in the connecting assembly (2), a connecting assembly (6) is installed on the side of the second connecting tube (3), a third connecting tube (7) is slidably installed above the second connecting tube (3), a lap rod (8) is installed on the third connecting tube (7), a first cross bar (9) is fixedly connected to the bottom of the lap rod (8), a second connecting block (10) is fixedly arranged in the middle of the first cross bar (9), a first traction steel rope (11) is fixedly connected to the second connecting block (10), a second cross bar (12) is fixedly connected to the second connecting tube (3), a guide wheel (13) is rotatably installed on the second cross bar (12), and the first traction steel rope (11) is rotatably connected to the guide wheel (13), and the first traction steel rope (11) is rotatably connected to the guide wheel (13) through the guide wheel (13). The guide wheel (13) is connected to the separation component (14), the separation component (14) is installed in the second connecting pipe (3), the top of the third connecting pipe (7) is installed with a top cover (15), an adjustment plate (16) is slidably installed in the top cover (15), an outer bushing (17) is fixedly connected to the adjustment plate (16), a ball shaft (18) is rotatably installed in the outer bushing (17) and the adjustment plate (16), an extraction pipe (19) is arranged in the ball shaft (18), a second slide plate (20) is arranged in the extraction pipe (19), a second traction steel rope (21) is fixedly connected to the second slide plate (20), a negative pressure component (22) is arranged on the top of the second traction steel rope (21), and a window (26) is installed on the second connecting pipe (3); The connecting assembly (2) comprises a first connecting pipe (201) fixedly connected to the first connecting pipe (1), a first baffle (202) fixedly connected to the first connecting pipe (201), a second connecting pipe (203) rotatably mounted on the first connecting pipe (1), and a second baffle (204) fixedly connected to the second connecting pipe (203); The connecting assembly (6) comprises a slider (601) slidably mounted on the second connecting tube (3); the slider (601) is fixedly connected to a first slider (602); the first slider (602) is fixedly provided with a first connecting block (603); the first connecting block (603) is fixedly provided with a connecting plate (604); the second connecting tube (3) is fixedly provided with a rubber plate (605); the first slider (602) and the connecting plate (604) are in contact with each other; The negative pressure assembly (22) comprises a sliding sleeve (2201) slidably mounted on the outer side of the extraction tube (19); a first connecting rod (2202) is fixedly connected to the sliding sleeve (2201); a connecting ring (2203) is fixedly connected to the first connecting rod (2202); an extension rod (2204) is fixedly arranged on the connecting ring (2203); the bottom of the extension rod (2204) is connected to the second traction steel rope (21); a third cross bar (2205) is fixedly arranged on the extraction tube (19); the second traction steel rope (21) is connected to the second slide plate (20) through the guidance of the third cross bar (2205); an elastic rope (2206) is fixedly connected to the bottom of the second slide plate (20); a convex ring (2207) is fixedly connected to the bottom of the elastic rope (2206); the convex ring (2207) and the extraction tube (19) are fixedly connected.

2. A cell separation and extraction device for leukemia testing according to claim 1, characterized in that: A convex block (4) is fixedly connected to the second connecting tube (3), and a sliding groove (5) for the convex block (4) to move is provided in the first connecting tube (1).

3. The cell separation and extraction device for leukemia testing according to claim 1, characterized in that: A rubber pressure plate (23) is fixedly connected to the third connecting tube (7), and the rubber pressure plate (23) is symmetrically distributed on both sides of the second connecting tube (3) and the third connecting tube (7). The third connecting tube (7), the lap rod (8) and the first cross rod (9) are fixedly connected to form an integral structure.

4. The cell separation and extraction device for leukemia testing according to claim 1, characterized in that: The separation assembly (14) includes a guide rod (1406) fixedly connected to the second connecting tube (3), an outer frame (1401) is slidably mounted on the outer side of the guide rod (1406), a sieve plate (1402) is fixedly arranged in the outer frame (1401), sieve holes (1403) and slits (1404) are arranged on the sieve plate (1402), a third connecting block (1405) is fixedly arranged in the middle of the sieve plate (1402), and the third connecting block (1405) is connected to the bottom of the first traction steel rope (11).

5. The cell separation and extraction device for leukemia testing according to claim 4, characterized in that: The outer frame (1401) and the sieve plate (1402) are both made of rubber material, the outer frame (1401) and the sieve plate (1402) have the same thickness, the depth of the slit (1404) is less than the thickness of the sieve plate (1402), and the position of each row of the sieve holes (1403) corresponds to the position of each slit (1404).

6. The cell separation and extraction device for leukemia testing according to claim 1, characterized in that: The outer wall of the adjustment plate (16) and the inner wall of the top cover (15) are in contact with each other, the extraction tube (19) forms a rotating structure with the adjustment plate (16) through the ball shaft (18), and the ball shaft (18) forms a sliding structure with the adjustment plate (16) and the top cover (15).

7. The cell separation and extraction device for leukemia testing according to claim 1, characterized in that: The elastic rope (2206) is evenly distributed along the circumference of the convex ring (2207), and the second slide plate (20) and the extraction tube (19) are slidably connected. The second slide plate (20) forms a lifting structure with the extraction tube (19) through the second traction steel rope (21), the extension rod (2204) and the third cross bar (2205).

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