Batch detection device for ELISA (enzyme-linked immuno sorbent assay) detection and use method of batch detection device
By designing an automated ELISA method detection device, including a two-way conveyor rack and pulse puncture device, the psychological burden of user's own puncture operation and medical waste disposal problems in the prior art is solved, and unified detection and result recognition of large-scale test strips are realized, improving the Test efficiency and safety.
Patent Information
- Application Number
- CN202310872044.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2023-07-17
- Publication Date
- 2025-01-17
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
The existing ELISA method detection method requires users to perform finger puncture operations on their own, resulting in a high psychological burden and it is difficult to centrally dispose of medical waste after testing at home.
A batch detection device for ELISA method is designed, including a two-way conveyor rack, pulse puncturer, pressure plate, annular pressure sensor and a code scanning camera. The unified detection and processing of the test strips is achieved through an automated two-way conveyor rack and pulse puncturer, and equipped with Disinfection components and batch identification devices, users can complete detection by scanning codes and automatically puncture.
The unified detection and processing of large batches of test strips has been realized, which has reduced the psychological burden on users. The problem of medical waste treatment is solved through automated processing and centralized identification devices, and the detection efficiency and safety are improved.
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Figure CN119322174A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of medical supplies, and in particular to a batch detection device for ELISA detection and a method for using the same. Background Art
[0002] Enzyme-linked immunosorbent assay, abbreviated as ELISA or ELASA, refers to a qualitative and quantitative detection method of immune response by binding soluble antigens or antibodies to solid phase carriers such as polystyrene and utilizing the specific binding of antigens and antibodies. Enzyme-linked immunosorbent assay is a classic experiment in immunology and most existing ELISAs require it.
[0003] Most of the existing detection methods are performed by oneself at home. During the self-operation process, the user is usually required to complete the puncture operation on the finger, which puts a heavy psychological burden on the user. At the same time, after the user performs the test at home, the medical waste generated is not easy to be centrally processed. Therefore, an ELISA batch detection device and a method of use thereof are proposed to solve the above-mentioned problems. Summary of the invention
[0004] 1. Technical issues to be resolved
[0005] In view of the shortcomings of the prior art, the present invention provides a batch detection device for ELISA detection and a method of using the same, which has the advantage of being able to conveniently perform unified detection and processing on large quantities of test strips, and solves the problem that most of the existing detection methods are performed by oneself at home. During the self-operation process, the user is usually required to complete the puncture operation on the finger, which puts a heavy psychological burden on the user. At the same time, after the user performs the test at home, the medical waste generated by the user is not easy to be centrally processed.
[0006] (II) Technical solution
[0007] The technical solution of the present invention for solving the above technical problems is as follows: A batch detection device for ELISA detection comprises a bidirectional conveying frame, a vertical conveying frame is fixedly installed on the top of the bidirectional conveying frame, a pulse puncturer is fixedly connected to the left side of the moving end of the vertical conveying frame, a pressure plate located below the pulse puncturer is fixedly connected to the left side of the moving end of the vertical conveying frame, an annular pressure sensor is fixedly installed on the bottom of the pressure plate, a puncture hole whose axis is in the same straight line as the axis of the annular pressure sensor is opened inside the pressure plate, an electric telescopic rod is fixedly installed on the bottom of the bidirectional conveying frame, a protective cover wrapped around the outside of the pressure plate is fixedly installed on the left side of the output end of the electric telescopic rod, and a code scanning camera is fixedly installed on the left side of the protective cover.
[0008] The beneficial effects of the present invention are:
[0009] The batch detection device for ELISA detection and the use method thereof have the advantage of being able to conveniently perform unified detection and processing on large quantities of test strips.
[0010] Based on the above technical solution, the present invention can also be improved as follows.
[0011] Furthermore, the bidirectional conveyor frame is composed of an L-shaped frame, a transverse conveyor belt and a longitudinal conveyor belt, and the transverse conveyor belt and the longitudinal conveyor belt are both arranged on the inner side of the L-shaped frame.
[0012] The beneficial effect of adopting the above further solution is that this arrangement facilitates the transportation of the test paper with a shell.
[0013] Furthermore, the pulse puncture device includes a cylinder fixed to the left side of the moving end of the vertical conveyor frame, the left side of the cylinder is connected to a solenoid valve, a buckle assembly is fixedly installed at the bottom of the output end of the cylinder, and a puncture needle is clamped on the inner side of the buckle assembly.
[0014] The beneficial effect of adopting the above further solution is that the pulse puncturer can perform a pulse action, which facilitates the puncture.
[0015] Furthermore, the buckle assembly includes a U-shaped block connected to the cylinder, and the inner opposite walls of the U-shaped block are fixedly installed with elastic springs, and the opposite sides of the two elastic springs are fixedly connected with extrusion sheets that are extruded by the puncture needle.
[0016] The beneficial effect of adopting the above further solution is that this arrangement can facilitate the installation and removal of the puncture needle.
[0017] Furthermore, triangular grooves are provided on opposite sides of the two extrusion sheets, and rubber pads are provided inside the triangular grooves and are in an extrusion state with the puncture needle.
[0018] The beneficial effect of adopting the above further solution is that this arrangement can prevent the puncture needle from sliding after the puncture is completed.
[0019] Furthermore, a batch identification device is fixedly installed on the top of the bidirectional conveying frame, and a disinfection component wrapped around the outside of the pulse puncture device is fixedly installed on the left side of the vertical conveying frame.
[0020] The beneficial effect of adopting the above further solution is that the provision of the disinfection component can prevent infection caused by repeated punctures.
[0021] A method for using a batch detection device for ELISA detection, comprising the following method:
[0022] Step 1: Set up a test paper with a shell and spray a QR code on its surface;
[0023] Step 2: The user points the QR code of the test paper with a shell toward the scanning camera for identification, and then places the test paper with a shell into the detection device;
[0024] Step 3: Place your finger facing upwards on the puncture site to complete the puncture;
[0025] Step 4: After the puncture is completed, the finger is pointed downward to drip blood onto the detection area of the shelled test paper to complete the test.
[0026] Furthermore, in addition to the above steps, the following steps should be added:
[0027] After waiting for the test strip to fully react, the batch recognition device will recognize the results and push the results to the user.
[0028] Furthermore, the method is implemented based on a programmable controller, and the programmable controller is connected to the cloud server via an RJ45 interface.
[0029] The beneficial effect of adopting the above further solution is that the cloud server can push the message of the detection result to the user's portable device. BRIEF DESCRIPTION OF THE DRAWINGS
[0030] Figure 1 It is a schematic diagram of the structure of the present invention;
[0031] Figure 2 This is a schematic diagram of the structure of the pulse puncture device of the present invention;
[0032] Figure 3 It is an enlarged view of point A in the figure of the present invention;
[0033] Figure 4 This is a diagram showing the connection between the buckle assembly and the puncture needle of the present invention;
[0034] Figure 5 This is a connection diagram between the protective cover and the barcode scanning camera of the present invention;
[0035] Figure 6 This is a connection diagram of the electric telescopic rod and the protective cover of the present invention;
[0036] Figure 7 This is a connection diagram between the annular pressure sensor and the pressure plate of the present invention.
[0037] In the figure: 1. Bidirectional conveyor frame; 2. Vertical conveyor frame; 3. Pulse puncture device; 31. Cylinder; 32. Solenoid valve; 33. Buckle assembly; 34. Puncture needle; 5. Press plate; 6. Annular pressure sensor; 7. Puncture hole; 8. Electric telescopic rod; 9. Protective cover; 10. Code scanning camera; 11. Batch recognition device. DETAILED DESCRIPTION
[0038] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0039] In the embodiment, Figure 1-7 A batch detection device for ELISA detection and a method for using the same are provided. The present invention comprises a bidirectional conveying frame 1, wherein a vertical conveying frame 2 is fixedly installed on the top of the bidirectional conveying frame 1, a pulse puncture device 3 is fixedly connected to the left side of the moving end of the vertical conveying frame 2, a pressing plate 5 located below the pulse puncture device 3 is fixedly connected to the left side of the moving end of the vertical conveying frame 2, an annular pressure sensor 6 is fixedly installed on the bottom of the pressing plate 5, a puncture hole 7 whose axis is in the same straight line as the axis of the annular pressure sensor 6 is opened inside the pressing plate 5, an electric telescopic rod 8 is fixedly installed on the bottom of the bidirectional conveying frame 1, a protective cover 9 wrapped around the outside of the pressing plate 5 is fixedly installed on the left side of the output end of the electric telescopic rod 8, and a code scanning camera 10 is fixedly installed on the left side of the protective cover 9.
[0040] The bidirectional conveyor frame 1 is composed of an L-shaped frame, a transverse conveyor belt and a longitudinal conveyor belt, and the transverse conveyor belt and the longitudinal conveyor belt are both arranged on the inner side of the L-shaped frame.
[0041] The longitudinal conveyor belt can transport the shelled test strips to the appropriate location to prevent them from being unable to be transported.
[0042] Among them, the pulse puncture device 3 includes a cylinder 31 fixed to the left side of the moving end of the vertical conveying frame 2, the left side of the cylinder 31 is connected to the electromagnetic valve 32, and a snap assembly 33 is fixedly installed at the bottom of the output end of the cylinder 31, and a puncture needle 34 is snapped on the inner side of the snap assembly 33.
[0043] When the pulse puncture device 3 is working, the electromagnetic valve 32 and the cylinder 31 are ventilated, and are set to quickly switch to the retracted state after being pushed out, so as to push out the puncture needle 34 and then retract it to complete the puncture operation.
[0044] The buckle assembly 33 includes a U-shaped block connected to the cylinder 31, and elastic springs are fixedly installed on the inner opposite walls of the U-shaped block, and the opposite sides of the two elastic springs are fixedly connected with extrusion sheets that are extruded by the puncture needle.
[0045] The two extrusion sheets have triangular grooves on opposite sides thereof, and rubber pads are arranged inside the triangular grooves and are in an extrusion state with the puncture needle 34 .
[0046] The puncture needle 34 should be in two sections, the diameter of the upper end is smaller than the diameter of the lower end, and the step is in contact with the extrusion sheet.
[0047] A batch identification device 11 is fixedly installed on the top of the bidirectional conveying frame 1 , and a disinfection component wrapped around the outside of the pulse puncture device 3 is fixedly installed on the left side of the vertical conveying frame 2 .
[0048] The batch identification device 11 performs corresponding timing after identifying the shelled test paper, and identifies the detection situation after the timing is completed.
[0049] The following usage methods are included:
[0050] Step 1: Set up a test paper with a shell and spray a QR code on its surface;
[0051] Step 2: The user points the QR code of the test paper with a shell toward the scanning camera 10 for identification, and then places the test paper with a shell into the detection device;
[0052] Step 3: Place your finger facing upwards on the puncture site to complete the puncture;
[0053] Step 4: After the puncture is completed, the finger is pointed downward to drip blood onto the detection area of the shelled test paper to complete the test.
[0054] In addition to the above steps, the following steps should be added:
[0055] After the test strips have fully reacted, the batch recognition device 11 recognizes the results and pushes the results to the user.
[0056] Among them, the method is implemented based on a programmable controller, and the programmable controller is connected to the cloud server through an RJ45 interface.
[0057] The beneficial effect of adopting the above further solution is that the cloud server can push the message of the detection result to the user's portable device.
[0058] Working principle:
[0059] Step 1: Scan the QR code on the shelled test paper with the scanning camera 10 to complete the registration. After the scanning is completed, the electric telescopic rod 8 controls the protective cover 9 to start to descend and expose the two-way conveying frame 1. The user can now place the shelled test paper on the two-way conveying frame 1, and the two-way conveying frame 1 adjusts the shelled test paper;
[0060] Step 2: Place the finger under the pressing plate 5, and the vertical conveying frame 2 starts to drive the left component to move. When the annular pressure sensor 6 contacts the user's finger, the vertical conveying frame 2 stops moving. At this time, the pulse puncture device 3 generates pulse puncture and controls the vertical conveying frame 2 to reset, which is convenient for the user to drip blood;
[0061] Step 3: After the blood collection is completed, the two-way conveyor rack 1 can transport the shelled test paper to the batch identification device 11 for processing. After the batch identification device 11 completes the processing, the discarded test paper used for detection can be processed uniformly.
[0062] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "comprise a ..." do not exclude the existence of other identical elements in the process, method, article or device including the elements.
[0063] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A batch detection device for ELISA detection, comprising a bidirectional conveyor frame (1), characterized in that: A vertical conveying frame (2) is fixedly installed on the top of the bidirectional conveying frame (1), a pulse puncture device (3) is fixedly connected to the left side of the movable end of the vertical conveying frame (2), a pressing plate (5) located below the pulse puncture device (3) is fixedly connected to the left side of the movable end of the vertical conveying frame (2), an annular pressure sensor (6) is fixedly installed on the bottom of the pressing plate (5), a puncture hole (7) whose axis is located on the same straight line as the axis of the annular pressure sensor (6) is opened inside the pressing plate (5), an electric telescopic rod (8) is fixedly installed on the bottom of the bidirectional conveying frame (1), a protective cover (9) wrapped around the outside of the pressing plate (5) is fixedly installed on the left side of the output end of the electric telescopic rod (8), and a code scanning camera (10) is fixedly installed on the left side of the protective cover (9).
2. The ELISA batch detection device according to claim 1, characterized in that: The bidirectional conveying frame (1) is composed of an L-shaped frame, a transverse conveying belt and a longitudinal conveying belt, and the transverse conveying belt and the longitudinal conveying belt are both arranged on the inner side of the L-shaped frame.
3. The batch detection device for ELISA detection according to claim 1, characterized in that: The pulse puncture device (3) comprises a cylinder (31) fixed to the left side of the moving end of the vertical conveying frame (2), the left side of the cylinder (31) is connected to a solenoid valve (32), a buckle assembly (33) is fixedly installed at the bottom of the output end of the cylinder (31), and a puncture needle (34) is clamped on the inner side of the buckle assembly (33).
4. The batch detection device for ELISA detection according to claim 3, characterized in that: The buckle assembly (33) comprises a U-shaped block connected to the cylinder (31), and the inner opposite walls of the U-shaped block are fixedly mounted with elastic springs, and the opposite sides of the two elastic springs are fixedly connected with extrusion sheets that are extruded by the puncture needle (34).
5. The batch detection device for ELISA detection according to claim 4, characterized in that: The opposite sides of the two extrusion sheets are provided with triangular grooves, and rubber pads are arranged inside the triangular grooves and are in an extrusion state with the puncture needle (34).
6. The batch detection device for ELISA detection according to claim 1, characterized in that: A batch identification device (11) is fixedly installed on the top of the bidirectional conveying frame (1), and a disinfection component wrapped around the outside of the pulse puncture device (3) is fixedly installed on the left side of the vertical conveying frame (2).
7. A method for using a batch detection device for ELISA detection according to any one of claims 1 to 6, characterized in that: Including the following usage: Step 1: Set up a test paper with a shell and spray a QR code on its surface; Step 2: The user points the QR code of the test paper with a shell toward the scanning camera (10) for identification, and then places the test paper with a shell into the detection device; Step 3: Place your finger facing upwards on the puncture site to complete the puncture; Step 4: After the puncture is completed, the finger is pointed downward to drop blood onto the detection area of the shelled test paper to complete the test.
8. The method for using the batch detection device for ELISA detection according to claim 7, characterized in that: In addition to the above steps, the following steps should be added: After the test paper has fully reacted, the batch recognition device (11) recognizes the result and pushes the result to the user.
9. The method for using the batch detection device for ELISA detection according to claim 8, characterized in that: The method is implemented based on a programmable controller, and the programmable controller is connected to a cloud server via an RJ45 interface.