Umbilical cord mesenchymal stem cell storage device

By designing an umbilical cord mesenchymal stem cell storage device that utilizes fans and airflow tubes, the problem of uneven refrigeration is solved and efficient refrigeration and storage of umbilical cord mesenchymal stem cells is achieved.

CN119325973AInactive Publication Date: 2025-01-21YUNNAN HEZE SOUTHWEST BIOLOGICAL SCI & TECH CO LTD
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Patent Information

Application Number
CN202411392966.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-10-08
Publication Date
2025-01-21
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

The existing umbilical cord mesenchymal stem cell storage device has the problem of uneven refrigeration, resulting in poor storage effect of overall umbilical cord mesenchymal stem cells.

Method used

An umbilical cord mesenchymal stem cell storage device is designed. The cold air generated by the cooling device is sucked through a fan, and the cold air is evenly transported to the storage bin through air flow tubes and zigzag tubes to ensure that the cold air is blown to the umbilical cord mesenchyme from different angles. On stem cells, improve the cold storage effect.

Benefits of technology

It achieves even distribution of cold air, improves the cold storage effect of umbilical cord mesenchymal stem cells, and ensures the storage quality and safety of the cells.

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Abstract

The invention discloses an umbilical cord mesenchymal stem cell storage device, and relates to the technical field of umbilical cord mesenchymal stem cell storage. The umbilical cord mesenchymal stem cell storage device comprises a storage bin, the inner wall of the storage bin is fixedly connected with a placement frame, the inner wall of the placement frame is slidably connected with a placement disc, the top of the storage bin is fixedly connected with a cooling device, and the outer wall of the storage bin is fixedly connected with a guide mechanism. According to the umbilical cord mesenchymal stem cell storage device, cold air generated by the cooling device is sucked through the draught fan and then conveyed into the storage bin through the airflow pipe, and the cold air generated by the cooling device is directly sucked and cannot be directly discharged by the cooling device, so that the position close to the cooling device is prevented from being supercooled, the temperature reduction imbalance is reduced, and the storage efficiency is improved. The gas entering the storage bin can enter the cooling device, the cold air in the cooling device is driven to flow through circular flow, and circular flow of the internal gas is ensured.
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Description

Technical Field

[0001] The present invention relates to the technical field of umbilical cord mesenchymal stem cell storage, in particular to an umbilical cord mesenchymal stem cell storage device. Background Art

[0002] Umbilical cord mesenchymal stem cell storage is an important way of health investment. The umbilical cord is usually regarded as medical waste after the baby is born, but the mesenchymal stem cells in it have great value. Storing these stem cells provides a potential resource for possible disease treatment in the future. Mesenchymal stem cells have multidirectional differentiation potential and can differentiate into multiple cell types. They show broad prospects in the treatment of nervous system diseases, cardiovascular diseases, immune system diseases, etc. The storage process is strictly regulated to ensure the activity and quality of the cells. The patent cited in China is CN113619914A, which discloses an umbilical cord mesenchymal stem cell storage device, belonging to the field of stem cell storage devices. An umbilical cord mesenchymal stem cell storage device includes: a box, a driving shaft, a rotating frame and a fixed column; the box is provided with a freezing chamber; the freezing chamber is rotatably connected to the driving shaft; the driving shaft is fixedly installed with the rotating frame; the fixed column is rotatably connected to the rotating frame; the fixed columns are evenly distributed around the circumference of the rotating frame; a fixed seat 1 is fixedly installed at one end of the rotating frame close to the fixed column; the fixed seat 1 is rotatably connected to a fixed shaft 1; the rotating frame is rotatably connected to a fixed shaft 2 at one end close to the fixed shaft 1; Umbilical cord mesenchymal stem cells need to be refrigerated at low temperatures. The position of the cooling device is fixed, so the cooling effect of the position close to the cooling device is higher than that of other positions, resulting in uneven overall refrigeration of umbilical cord mesenchymal stem cells, which in turn affects the overall storage of umbilical cord mesenchymal stem cells. Summary of the invention

[0003] In view of the deficiencies of the prior art, the present invention provides an umbilical cord mesenchymal stem cell storage device to solve the problems raised in the above background technology.

[0004] To achieve the above objectives, the present invention is implemented through the following technical solutions: an umbilical cord mesenchymal stem cell storage device, comprising a storage bin, the inner wall of the storage bin is fixedly connected to a placement rack, the inner wall of the placement rack is slidably connected to a placement plate, the top of the storage bin is fixedly connected to a cooling device, and the outer wall of the storage bin is fixedly connected to a guide mechanism; The guiding mechanism comprises: A sealing block, wherein a hole is formed on the back of the storage bin, and the sealing block is fixedly connected in the hole of the storage bin; The fan, the outer wall of which is fixedly connected to the outer wall of the sealing block, sucks the cold air generated by the cooling device, and then transports it to the storage bin through the airflow pipe. The cold air generated by the cooling device is directly sucked, so it will not be directly discharged from the cooling device, avoiding overcooling near the cooling device, reducing uneven cooling, and the gas entering the storage bin will enter the cooling device. The circulating flow drives the cold air flow in the cooling device, ensuring the circulating flow of the internal gas, ensuring the sealing of the device, and avoiding the damage of the umbilical cord mesenchymal stem cells caused by the outside air. The airflow pipe is located at the position of multiple trays, so the sucked cold air is directly facing the umbilical cord mesenchymal stem cells, improving the position where the cold air is evenly facing the umbilical cord mesenchymal stem cells, and improving the refrigeration effect of the umbilical cord mesenchymal stem cells; A connecting pipe, both ends of which are fixedly connected between the fan and the cooling device.

[0005] Preferably, an airflow pipe is fixedly connected to the bottom of the fan, and the airflow pipe is inserted into the storage bin.

[0006] Preferably, a zigzag tube is fixedly connected to the outer wall of the airflow tube, and a spring is fixedly connected between the top of the zigzag tube and the bottom of the storage bin. The top of the zigzag tube is connected by the spring, so that the zigzag tube and the airflow tube can move within a limited range, utilizing the rotation of the fan blades inside the fan. When the elliptical block rotates to the horizontal direction, it will be squeezed onto the airflow tube, which will drive the airflow tube and the zigzag tube to shake. The direction of the airflow will change during the shaking of the airflow tube, and then it will blow onto the umbilical cord mesenchymal stem cells from different angles, changing the angle of the airflow, so that the cold air is guided to the umbilical cord mesenchymal stem cells from different angles, thereby improving the refrigeration effect of the umbilical cord mesenchymal stem cells, and the up and down movement of the horizontal plate will drive the cold air to mix evenly.

[0007] Preferably, the outer wall of the fan is rotatably connected to a first bearing at a position inside the storage bin, and the inner walls of the fan and the first bearing are rotatably connected to an elliptical block, and the elliptical block is in active contact with the airflow pipe.

[0008] Preferably, the outer wall of the storage bin is rotatably connected to a door panel, the inner wall of the door panel is fixedly connected to an auxiliary mechanism, the auxiliary mechanism comprises a slide rail, and the slide rail is fixedly connected to the inner wall of the door panel.

[0009] Preferably, an outer wall of the slide rail is slidably connected to an electric slider, and an outer wall of the electric slider is fixedly connected to a collar.

[0010] Preferably, the inner wall of the ring is clamped with a limiting ball, the outer wall of the limiting ball is fixedly connected to a second bearing, the outer wall of the second bearing is rotatably connected to a transverse plate, the inner wall of the door panel is fixedly connected to a protruding block, and the protruding block is in movably contact with the transverse plate.

[0011] Preferably, the outer wall of the horizontal plate is fixedly connected with an elastic wire, and when the horizontal plate is squeezed by the raised block, the horizontal plate will be tilted toward the placement plate. Then, after the elastic wire and the rubber ball on the horizontal plate hit the side of the placement plate, the horizontal plate will move toward the inner wall of the door panel, so it can continuously contact with the placement plate. The impact of the rubber ball on the placement plate will cause the placement plate to vibrate, thereby driving the umbilical cord mesenchymal stem cells and the liquid to mix, reducing the precipitation of the umbilical cord mesenchymal stem cells, ensuring the mixing of the liquid reagent and the umbilical cord mesenchymal stem cells, and improving the storage effect of the umbilical cord mesenchymal stem cells. When the vibration rod passes through the vibration block, the collision between the two will also cause the door panel to vibrate, and the vibration is transmitted to the placement plate, further mixing the umbilical cord mesenchymal stem cells and the liquid reagent. The outer wall of the elastic wire is fixedly connected with the rubber ball, the outer wall of the horizontal plate is fixedly connected with the vibration rod, and the inner wall of the door panel is fixedly connected with the vibration block, and the vibration rod is in active contact with the vibration block.

[0012] The present invention provides an umbilical cord mesenchymal stem cell storage device, which has the following beneficial effects: 1. The umbilical cord mesenchymal stem cell storage device sucks the cold air generated by the cooling device through a fan, and then transports it to the storage bin through an airflow pipe. The cold air generated by the cooling device is directly sucked, so it will not be directly discharged from the cooling device, avoiding overcooling near the cooling device and reducing uneven cooling. The gas entering the storage bin will enter the cooling device, and the circulating flow drives the cold air flow in the cooling device, ensuring the circulating flow of the internal gas, ensuring the sealing of the device, and avoiding damage to the umbilical cord mesenchymal stem cells caused by the outside air. The airflow pipe is located at the position of multiple trays, so the sucked cold air is directly facing the umbilical cord mesenchymal stem cells, which improves the position where the cold air is evenly facing the umbilical cord mesenchymal stem cells and improves the refrigeration effect of the umbilical cord mesenchymal stem cells.

[0013] 2. The umbilical cord mesenchymal stem cell storage device is connected by a spring at the top of the zigzag tube, so that the zigzag tube and the airflow tube can move within a limited range, and the rotation of the fan blades inside the fan is utilized. When the elliptical block rotates to the horizontal direction, it will be squeezed onto the airflow tube, which will drive the airflow tube and the zigzag tube to shake. The airflow tube will change the direction of the airflow during the shaking process, and then blow to the umbilical cord mesenchymal stem cells from different angles, changing the angle of the airflow, so that the cold air is guided to the umbilical cord mesenchymal stem cells from different angles, thereby improving the refrigeration effect of the umbilical cord mesenchymal stem cells, and the up and down movement of the horizontal plate will drive the cold air to be mixed evenly.

[0014] 3. The umbilical cord mesenchymal stem cell storage device tilts the horizontal plate toward the placement tray by being squeezed by the raised block on the horizontal plate. Then, after the elastic wire and rubber ball on the horizontal plate hit the side of the placement tray, the horizontal plate moves toward the inner wall of the door panel, so that it can continuously contact with the placement tray. The impact of the rubber ball on the placement tray will cause the placement tray to vibrate, thereby driving the umbilical cord mesenchymal stem cells and the liquid to mix, reducing the precipitation of the umbilical cord mesenchymal stem cells, ensuring the mixing of the liquid reagent and the umbilical cord mesenchymal stem cells, and improving the storage effect of the umbilical cord mesenchymal stem cells. When the vibration rod passes through the vibration block, the collision between the two will also cause the door panel to vibrate, and the vibration is transmitted to the placement tray, further mixing the umbilical cord mesenchymal stem cells and the liquid reagent. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic diagram of the axial side stereoscopic structure of the present invention; Figure 2 It is a bottom-up three-dimensional structural schematic diagram of the present invention; Figure 3 It is a schematic diagram of the back three-dimensional structure of the present invention; Figure 4 For the present invention Figure 3 Schematic diagram of the cross-section structure; Figure 5 For the present invention Figure 4 The enlarged structural diagram of the middle B part; Figure 6 It is a schematic diagram of the local structure of the spring of the present invention; Figure 7 It is a schematic diagram of the local structure of the elliptical plate of the present invention; Figure 8 For the present invention Figure 1 A schematic diagram of the enlarged structure of the middle part A; Fig. 9 It is a schematic diagram of the partial structure of the auxiliary mechanism of the present invention.

[0016] In the figure: 1. storage bin; 2. placement plate; 3. placement rack; 4. cooling device; 5. door panel; 6. guiding mechanism; 61. fan; 62. connecting pipe; 63. spring; 64. zigzag pipe; 65. air flow pipe; 66. elliptical block; 67. first bearing; 68. sealing block; 7. raised block; 8. auxiliary mechanism; 81. electric slider; 82. sleeve ring; 83. limiting ball; 84. second bearing; 85. cross plate; 86. elastic wire; 87. rubber ball; 88. vibration rod; 89. vibration block; 810. slide rail. DETAILED DESCRIPTION

[0017] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0018] Examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.

[0019] For example, see Figure 1-7 The present invention provides a technical solution: an umbilical cord mesenchymal stem cell storage device, comprising a storage bin 1, a placement rack 3 is fixedly connected to the inner wall of the storage bin 1, a placement plate 2 is slidably connected to the inner wall of the placement rack 3, a cooling device 4 is fixedly connected to the top of the storage bin 1, and a guide mechanism 6 is fixedly connected to the outer wall of the storage bin 1; The guiding mechanism 6 comprises: A sealing block 68 is provided on the back of the storage bin 1 with a hole, and the sealing block 68 is fixedly connected in the hole of the storage bin 1; The fan 61, the outer wall of the fan 61 is fixedly connected to the outer wall of the sealing block 68; The connecting pipe 62 has two ends fixedly connected between the fan 61 and the cooling device 4 .

[0020] An airflow pipe 65 is fixedly connected to the bottom of the fan 61 , and the airflow pipe 65 is inserted into the storage bin 1 .

[0021] The outer wall of the airflow pipe 65 is fixedly connected with a zigzag pipe 64 , and a spring 63 is fixedly connected between the top of the zigzag pipe 64 and the bottom of the storage bin 1 .

[0022] The outer wall of the fan 61 is rotatably connected to a first bearing 67 located inside the storage bin 1 , and the inner walls of the fan 61 and the first bearing 67 are rotatably connected to an elliptical block 66 , which is in active contact with the airflow tube 65 .

[0023] The outer wall of the storage bin 1 is rotatably connected to a door panel 5 , and the inner wall of the door panel 5 is fixedly connected to an auxiliary mechanism 8 . The auxiliary mechanism 8 includes a slide rail 810 , and the slide rail 810 is fixedly connected to the inner wall of the door panel 5 .

[0024] When in use, the umbilical cord mesenchymal stem cells to be stored are placed on the placement tray 2, and then the placement tray 2 is pushed into the placement rack 3. The door panel 5 can be closed on the storage bin 1 to keep the storage bin 1 sealed, and the cooling device 4 can cool down the storage bin 1. Combined with Figure 3 and attached Figure 5As shown, the fan 61 is connected to the cooling device 4 through the connecting pipe 62, and can suck the cold air generated by the cooling device 4, and then transport it to the storage bin 1 through the airflow pipe 65. The cold air generated by the cooling device 4 is directly sucked, so it will not be directly discharged from the cooling device 4, and then the gas entering the storage bin 1 will enter the cooling device 4, and the circulating flow drives the cold air in the cooling device 4 to flow. The airflow pipe 65 is located at the position of multiple trays 2, so the sucked cold air is directly facing the umbilical cord mesenchymal stem cells; Combined with Figure 6 and attached Figure 7 As shown, the top of the zigzag tube 64 is connected by a spring 63. The spring 63 itself is elastic, so the zigzag tube 64 and the airflow tube 65 can move within a limited range. The fan 61 has rotating blades to guide the airflow. The rotation of the blades drives the rotation of the elliptical block 66. When the elliptical block 66 rotates to the horizontal direction, it will squeeze the airflow tube 65, and then drive the airflow tube 65 and the zigzag tube 64 to shake. The airflow tube 65 will change the direction of the airflow during the shaking process, and then blow it onto the umbilical cord mesenchymal stem cells from different angles.

[0025] For example 2, please refer to Figure 1-9 Based on the first embodiment, the present invention provides a technical solution: The outer wall of the slide rail 810 is slidably connected to an electric slider 81 , and the outer wall of the electric slider 81 is fixedly connected to a collar 82 .

[0026] The inner wall of the ring 82 is clamped with a limiting ball 83, the outer wall of the limiting ball 83 is fixedly connected to a second bearing 84, the outer wall of the second bearing 84 is rotatably connected to a transverse plate 85, and the inner wall of the door panel 5 is fixedly connected to a protruding block 7, which is in active contact with the transverse plate 85.

[0027] The outer wall of the horizontal plate 85 is fixedly connected with an elastic wire 86, the outer wall of the elastic wire 86 is fixedly connected with a rubber ball 87, the outer wall of the horizontal plate 85 is fixedly connected with a vibration rod 88, the inner wall of the door panel 5 is fixedly connected with a vibration block 89, and the vibration rod 88 is in active contact with the vibration block 89.

[0028] When in use, during the storage process, the electric slider 81 is powered on and starts to move on the slide rail 810. During the movement, the electric slider 81 drives the horizontal plate 85 to move through the connection between the ring 82 and the limit ball 83. When the horizontal plate 85 moves to the position of the protruding block 7, the horizontal plate 85 is squeezed by the protruding block 7, which will cause the horizontal plate 85 to tilt toward the placement tray 2. Then, after the elastic wire 86 and the rubber ball 87 on the horizontal plate 85 hit the side of the placement tray 2, the horizontal plate 85 will move toward the inner wall of the door panel 5. During the storage process, the umbilical cord mesenchymal stem cells inside the placement tray 2 are cultured in a mixed manner using nutrient solution and other liquids. Under precipitation, the liquid will be stratified with the umbilical cord mesenchymal stem cells, so the impact of the rubber ball 87 on the placement tray 2 will cause the placement tray 2 to vibrate, thereby driving the umbilical cord mesenchymal stem cells and the liquid to mix. Then, when the vibration rod 88 passes the vibration block 89, the collision of the two will also cause the door panel 5 to vibrate, and the vibration is transmitted to the placement tray 2. When necessary, the door panel 5 can be opened to take out the stored umbilical cord mesenchymal stem cells.

[0029] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. An umbilical cord mesenchymal stem cell storage device, comprising a storage bin (1), characterized in that: The inner wall of the storage bin (1) is fixedly connected to a placement rack (3), the inner wall of the placement rack (3) is slidably connected to a placement plate (2), the top of the storage bin (1) is fixedly connected to a cooling device (4), and the outer wall of the storage bin (1) is fixedly connected to a guide mechanism (6); The guiding mechanism (6) comprises: A sealing block (68), wherein a hole is formed on the back of the storage bin (1), and the sealing block (68) is fixedly connected to the hole of the storage bin (1); A fan (61), wherein an outer wall of the fan (61) is fixedly connected to an outer wall of a sealing block (68); A connecting pipe (62), wherein both ends of the connecting pipe (62) are respectively fixedly connected between the fan (61) and the cooling device (4).

2. The umbilical cord mesenchymal stem cell storage device according to claim 1, characterized in that: The bottom of the fan (61) is fixedly connected to an airflow pipe (65), and the airflow pipe (65) is inserted into the storage bin (1).

3. The umbilical cord mesenchymal stem cell storage device according to claim 2, characterized in that: The outer wall of the airflow pipe (65) is fixedly connected to a zigzag pipe (64), and a spring (63) is fixedly connected between the top of the zigzag pipe (64) and the bottom of the storage bin (1).

4. The umbilical cord mesenchymal stem cell storage device according to claim 3, characterized in that: The outer wall of the fan (61) is rotatably connected to a first bearing (67) at a position located inside the storage bin (1), and the inner walls of the fan (61) and the first bearing (67) are rotatably connected to an elliptical block (66), and the elliptical block (66) is in active contact with the airflow pipe (65).

5. The umbilical cord mesenchymal stem cell storage device according to claim 1, characterized in that: The outer wall of the storage bin (1) is rotatably connected to a door panel (5), the inner wall of the door panel (5) is fixedly connected to an auxiliary mechanism (8), the auxiliary mechanism (8) comprising a slide rail (810), and the slide rail (810) is fixedly connected to the inner wall of the door panel (5).

6. The umbilical cord mesenchymal stem cell storage device according to claim 5, characterized in that: The outer wall of the slide rail (810) is slidably connected to an electric slider (81), and the outer wall of the electric slider (81) is fixedly connected to a collar (82).

7. The umbilical cord mesenchymal stem cell storage device according to claim 6, characterized in that: The inner wall of the sleeve ring (82) is clamped with a limiting ball (83), the outer wall of the limiting ball (83) is fixedly connected to a second bearing (84), the outer wall of the second bearing (84) is rotatably connected to a transverse plate (85), and the inner wall of the door panel (5) is fixedly connected to a protruding block (7), the protruding block (7) being in movably contact with the transverse plate (85).

8. The umbilical cord mesenchymal stem cell storage device according to claim 7, characterized in that: An elastic wire (86) is fixedly connected to the outer wall of the transverse plate (85), a rubber ball (87) is fixedly connected to the outer wall of the elastic wire (86), a vibration rod (88) is fixedly connected to the outer wall of the transverse plate (85), a vibration block (89) is fixedly connected to the inner wall of the door panel (5), and the vibration rod (88) is in active contact with the vibration block (89).

Citation Information

Patent Citations

  • Umbilical cord mesenchymal stem cell storage device

    CN113619914A