Composition for treating xerophthalmia

Abstract

The invention provides a composition for treating xerophthalmia and a preparation method thereof, and relates to the field of traditional Chinese medicinal materials, the composition comprises the following raw materials by weight: 1-5 parts of alum, 5-10 parts of myrrh, 5-10 parts of frankincense, 20-50 parts of calamine, 1-5 parts of pearl, 1-5 parts of musk, 1-5 parts of borneol and 1-2 parts of vermilion. The preparation method comprises the following steps: crushing the alum, the myrrh, the frankincense, the pearl, the musk and the borneol flakes to obtain medicine powder; and S3, decocting honey until the honey juice is golden yellow to obtain honey juice, mixing the honey juice, the medicinal powder in the step S1 and calamine, uniformly stirring to prepare pills, and coating the surfaces of the pills with vermilion. All the raw materials are matched with one another, and xerophthalmia can be rapidly and effectively treated.

Description

Technical Field

[0001] The present invention relates to the field of Chinese medicinal materials, and in particular to a composition for treating dry eye and a preparation method thereof. Background Art

[0002] Dry eye is a common eye disease, which is mainly manifested by symptoms such as dry eyes, pain, itching, blurred vision, etc., which may be caused by a variety of factors. Dry eye can be divided into five categories according to the cause: water deficiency, lipid deficiency, abnormal tear dynamics, mucin deficiency and mixed dry eye. The severity of symptoms can be divided into mild, moderate and severe. The causes are diverse, including eye diseases, systemic diseases, environmental factors, etc. It is more common in the elderly population, and women, those who use electronic products for a long time, and those who use eye drops for a long time are more likely to get the disease.

[0003] There are various treatments for dry eyes, including medication, physical therapy, and surgical treatment. Medication can use sodium hyaluronate eye drops, artificial tears, vitamin A, bromhexine, and pilocarpine, neostigmine, and other drugs. Surgical treatment includes tarsal suture and punctum closure.

[0004] In the field of traditional Chinese medicine, there are also many prescriptions for treating dry eyes. For example, patent 202211458940.6 discloses a Chinese medicine for treating dry eyes, which includes 15-25g of Codonopsis pilosula, 3-9g of honey-fried ephedra floss, 6-12g of Cimicifuga heracleifolia, 3-6g of cinnamon twig, 12-18g of Bupleurum chinense, 12-18g of Radix Ophiopogonis and 3-9g of Licorice. The preparation method of this Chinese medicine is simple, the raw materials are abundant, it is easy to produce, the efficacy is stable and reliable, it is safe to take, the effect and patient compliance are very good, it can make the body fluid fully moisturize the eyes, it has a significant therapeutic effect on dry eyes, and it is an innovation in the treatment of dry eyes. The Chinese medicine is decocted and taken as a decoction to treat dry eyes. Patent 201610641355.8 discloses a formula for treating dry eyes, including 12 grams of Sophora japonica, 20 grams of Liuqu, 10 grams of Leiwan, 5 grams of Jinwen, 4 grams of Curculigo, 3 grams of honey, 6 grams of Pinellia, 6 grams of Lily, 10 grams of Rumex, and 15 grams of Sophora japonica. The formula for treating dry eyes of the present invention is suitable for patients with dry eyes caused by various conditions. This formula has the special curative effects of clearing away heat and detoxifying, reducing swelling and relieving pain, and is a good medicine for treating dry eyes. This prescription is also used to treat dry eyes by decocting and taking decoction.

[0005] There are various Chinese medicine prescriptions for treating dry eye in the prior art, but most of them require decocting Chinese medicine and taking decoctions orally, which is not convenient for taking medicine at any time and is inconvenient to use. Summary of the invention

[0006] The purpose of the present invention is to provide a composition for treating dry eye syndrome, which can be directly applied to the skin around the eyes to effectively treat and relieve dry eye syndrome.

[0007] Another object of the present invention is to provide a method for preparing a composition for treating dry eye, wherein each medicinal material is made into pills, and when in use, the pills are dissolved and applied around the eyes, which is convenient to use, and the drug can directly reach the lesion and take effect quickly.

[0008] The present invention solves the technical problem by adopting the following technical solutions.

[0009] On the one hand, an embodiment of the present invention provides a composition for treating dry eye, comprising the following raw materials, by weight: 1-5 parts of alum, 5-10 parts of myrrh, 5-10 parts of frankincense, 20-50 parts of calamine, 1-5 parts of pearl, 1-5 parts of musk, 1-5 parts of plum tablets, and 1-2 parts of vermilion.

[0010] In some embodiments of the present invention, the following raw materials are included by weight: 2 parts of alum, 6 parts of myrrh, 8 parts of frankincense, 30 parts of calamine, 3 parts of pearls, 2 parts of musk, 1 part of plum tablets, and 1.5 parts of vermilion.

[0011] In some embodiments of the present invention, the following raw materials are included by weight: 5 parts of alum, 10 parts of myrrh, 10 parts of frankincense, 30 parts of calamine, 5 parts of pearls, 5 parts of musk, 5 parts of plum tablets, and 2 parts of vermilion.

[0012] In some embodiments of the present invention, the calamine is prepared by the following method: crushing block calamine, putting it into a container, adding water, grinding it into a paste; adding water and stirring it, standing to separate, pouring out the upper suspension; grinding the coarse particles in the lower layer again, repeating the operation, combining the suspension, standing, removing the upper clear liquid, drying, and grinding it into powder to obtain calamine. The particle size of calamine is 120-150 mesh.

[0013] On the other hand, an embodiment of the present invention provides a method for preparing a composition for treating dry eye, comprising: S1, crushing alum, myrrh, frankincense, pearl, musk, and plum tablets to obtain a medicine powder;

[0014] S2, boiling honey until it turns golden yellow to obtain honey juice, mixing the honey juice, the medicinal powder in step S1 and calamine, stirring evenly to make pills, and then coating the surface of the pills with vermilion.

[0015] In some embodiments of the present invention, in step S1, the particle size of the powder is 120-150 mesh.

[0016] In some embodiments of the present invention, in step S2, the mass ratio of the honey juice to the medicinal powder is 1:1.

[0017] Compared with the prior art, the embodiments of the present invention have at least the following advantages or beneficial effects:

[0018] The composition provided by the present invention comprises 1-5 parts of alum, 5-10 parts of myrrh, 5-10 parts of frankincense, 20-50 parts of calamine, 1-5 parts of pearl, 1-5 parts of musk, 1-5 parts of plum slices, and 1-2 parts of silver vermilion, wherein alum is cold in nature, has the effects of clearing away heat and detoxicating, astringing and stopping sweating, is a monarch drug, and dominates the overall situation. Myrrh can promote blood circulation and remove blood stasis, and frankincense can promote qi circulation and relieve pain. The two complement each other, and jointly assist the monarch drug to alleviate the symptoms of dry eyes. Calamine clears heat and improves eyesight, pearl moisturizes and nourishes, musk promotes blood circulation and clears the orifices, and plum slices clear heat and detoxicate. All the medicines are combined, which can not only restrict the coldness of the monarch drug, but also enhance the therapeutic effect and make the drug power more balanced. The above-mentioned raw materials cooperate with each other, and can quickly and effectively treat dry eyes.

[0019] The preparation method provided by the present invention comprises the following steps: most of the raw materials are crushed into powder, mixed with honey to make pills, and silver vermilion is coated on the surface. The preparation method is simple and efficient, and the prepared pills are convenient to carry and use at any time. Secondly, the present invention prepares the raw materials into pills, dissolves the pills when in use, and applies them around the eyes. The use is convenient, and the medicine can directly reach the lesion and take effect quickly. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for use in the embodiments are briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without creative work.

[0021] Figure 1 A physical picture of a composition provided by an embodiment of the present invention; DETAILED DESCRIPTION

[0022] In order to make the purpose, technical scheme and advantages of the embodiments of the present invention clearer, the technical scheme in the embodiments of the present invention will be described clearly and completely below. If the specific conditions are not specified in the embodiments, they are carried out according to conventional conditions or conditions recommended by the manufacturer. If the manufacturer of the reagents or instruments used is not specified, they are all conventional products that can be purchased commercially.

[0023] It should be noted that, in the absence of conflict, the embodiments of the present invention and the features in the embodiments can be combined with each other. The present invention will be described in detail below with reference to specific embodiments.

[0024] On the one hand, an embodiment of the present invention provides a composition for treating dry eye, comprising the following raw materials, by weight: 1-5 parts of alum, 5-10 parts of myrrh, 5-10 parts of frankincense, 20-50 parts of calamine, 1-5 parts of pearl, 1-5 parts of musk, 1-5 parts of plum tablets, and 1-2 parts of vermilion.

[0025] In some embodiments of the present invention, the following raw materials are included by weight: 2 parts of alum, 6 parts of myrrh, 8 parts of frankincense, 30 parts of calamine, 3 parts of pearls, 2 parts of musk, 1 part of plum tablets, and 1.5 parts of vermilion.

[0026] In some embodiments of the present invention, the following raw materials are included by weight: 5 parts of alum, 10 parts of myrrh, 10 parts of frankincense, 30 parts of calamine, 5 parts of pearls, 5 parts of musk, 5 parts of plum tablets, and 2 parts of vermilion.

[0027] Alum: It has the effects of antibacterial and anti-inflammatory, controlling sweat secretion, drying dampness and relieving itching. It can also be used to treat diseases such as epilepsy and hepatitis, and can be used to relieve symptoms such as mouth sores and burns.

[0028] Myrrh: pungent, bitter, and flat in nature. It enters the heart, liver, and spleen meridians. It is pungent, dispersing, bitter, and fragrant, and has a flat nature. It enters the heart, liver, and spleen meridians. It is good at promoting blood circulation. When blood is active, pain is relieved, swelling is reduced, and muscles are regenerated, so it has the functions of relieving pain, reducing swelling, and promoting muscle growth. It is an important medicine in traumatology, and is commonly used to treat various pains caused by internal and external blood stasis and swelling and pain caused by carbuncle. Oral administration is easy to damage the vital energy due to dispersing, and external application is not conducive to pus discharge due to promoting muscle growth. Therefore, when treating sores and swellings: it can be taken before ulceration, but not after ulceration; it can be applied without pus, but not when there is a lot of pus. It contains volatile oils, resin components, furan sesquiterpenoid compounds, etc. It has the effects of dispersing blood stasis, relieving pain, reducing swelling, and promoting muscle growth. It is used for chest pain, epigastric pain, dysmenorrhea, amenorrhea, postpartum blood stasis, abdominal pain caused by lumps, rheumatic pain, traumatic injuries, and carbuncles and sores.

[0029] Frankincense: pungent, bitter, warm. It enters the heart, liver, and spleen meridians. It is pungent and fragrant, dispersing, bitter, warming, and enters the heart, liver, and spleen meridians. It is good at promoting blood circulation. When blood is active, pain is relieved, tendons are stretched, swelling is reduced, and muscles are regenerated. Therefore, it can promote blood circulation and stop pain, reduce swelling, promote muscle growth, and stretch tendons. It is an important medicine for traumatology, suitable for both blood stasis and sores. Oral administration is easy to damage the vital energy due to dispersing, and external application is not conducive to pus discharge due to muscle growth. Therefore, when treating sores and swellings: it can be taken before ulceration, but not after ulceration; it can be applied if there is no pus, but not if there is a lot of pus. It contains volatile oils, resin ingredients, etc. It has the effects of promoting blood circulation, relieving pain, reducing swelling and promoting muscle growth. It is used for chest pain, epigastric pain, dysmenorrhea, amenorrhea, postpartum blood stasis, abdominal pain due to stagnation, rheumatic arthralgia, tendon and vein spasm, traumatic injury, carbuncle, sore.

[0030] Calamine: detoxifies, improves eyesight, removes cataracts, absorbs moisture, relieves itching and heals ulcers. It is mainly used to treat eye diseases and skin itching.

[0031] Pearl: It has the effects of calming the nerves, improving eyesight, removing cataracts, detoxifying and promoting tissue regeneration. It is often used to treat symptoms such as palpitations, insomnia, convulsions and epilepsy.

[0032] Musk: It can reduce swelling and relieve pain. It is often used to treat various pains and inflammations. Musk is pungent and warm in nature. It enters the heart and spleen meridians. Musk is pungent, dispersing, warming and unblocking. Its fragrance is moving. It enters the heart and spleen meridians and is good at opening the orifices and blocking them. It is a good medicine for opening the orifices and refreshing the mind. It is suitable for treating closed syndrome and coma, whether it is cold or hot. It is also a good product for promoting blood circulation, unblocking menstruation and relieving pain. It can treat various blood stasis syndromes, whether they are new or long-standing. In addition, it is often used for sores, dead fetuses and retained placenta, etc. It contains musk macrocyclic components, steroid components, proteins, polypeptides, amino acids and other components. It has the functions of opening the orifices and refreshing the mind, promoting blood circulation and unblocking menstruation, reducing swelling and relieving pain.

[0033] Vermillion: It can attack toxins, kill insects, dry up dampness and eliminate phlegm. It is often used to treat carbuncle, swelling, ulcer and other symptoms.

[0034] Mei tablets are natural dextrorotatory borneol.

[0035] The composition provided by the present invention, when used, the musk in the composition has a strong wandering property, which may cause uterine contraction and increase the risk of miscarriage. Drugs for promoting blood circulation and removing blood stasis such as frankincense and myrrh may also have an adverse effect on the stability of the fetus when used during pregnancy, and are prohibited for pregnant women. People with allergic constitutions should use it with caution, as the various drug components in the composition may become allergens and trigger allergic reactions. In particular, patients who are allergic to components such as pearls and musk may experience severe allergic symptoms such as skin itching, redness, and dyspnea. Patients with hemorrhagic diseases should avoid using it. Drugs such as frankincense and myrrh in the prescription have a certain blood circulation effect, which may aggravate bleeding tendency and cause worsening of the condition. People with liver and kidney dysfunction should be cautious.

[0036] In some embodiments of the present invention, the calamine is prepared by the following method: crushing block calamine, putting it into a container, adding water, grinding it into a paste; adding water and stirring it, standing to separate, pouring out the upper suspension; grinding the coarse particles in the lower layer again, repeating the operation, combining the suspension, standing, removing the upper clear liquid, drying, and grinding it into powder to obtain calamine. The particle size of calamine is 120-150 mesh.

[0037] When preparing calamine powder, measures should be taken to prevent the drug powder from flying and polluting the environment. After standing, floating objects on the water surface should be removed to avoid impurity contamination.

[0038] On the other hand, an embodiment of the present invention provides a method for preparing a composition for treating dry eye, comprising: S1, crushing alum, myrrh, frankincense, pearl, musk, and plum tablets to obtain a medicine powder;

[0039] S2, boiling honey until it turns golden yellow to obtain honey juice, mixing the honey juice, the medicinal powder in step S1 and calamine, stirring evenly to make pills, and then coating the surface of the pills with vermilion.

[0040] In some embodiments of the present invention, in step S1, the particle size of the powder is 120-150 mesh.

[0041] In some embodiments of the present invention, in step S2, the mass ratio of the honey juice to the medicinal powder is 1:1.

[0042] The features and performance of the present invention are further described in detail below in conjunction with the embodiments.

[0043] Example 1

[0044] Prepare the raw materials according to the following ratio:

[0045] 2 parts of alum, 6 parts of myrrh, 8 parts of frankincense, 30 parts of calamine, 3 parts of pearls, 2 parts of musk, 1 part of plum tablets, and 1.5 parts of vermilion.

[0046] The composition of this embodiment was prepared as follows:

[0047] The alum, myrrh, frankincense, pearl, musk, and plum tablets are crushed, passed through a 150-mesh sieve, and the sieve portion is taken to obtain a medicinal powder;

[0048] S2, boiling honey until the honey juice is golden yellow to obtain honey juice, mixing the honey juice, the medicinal powder of step S1 and calamine, stirring evenly, making pills, and then coating the surface of the pills with silver vermilion. The mass ratio of the honey juice to the medicinal powder is 1:1.

[0049] In the present embodiment, the calamine used is prepared by the following method: crushing the block calamine, putting it into a container, adding water, grinding it into a paste; adding water and stirring it, standing it for stratification, and pouring out the upper suspension; grinding the coarse particles in the lower layer again, repeating the operation, combining the suspension, standing it, removing the upper clear liquid, drying it, grinding it into powder, passing it through a 150-mesh sieve, and taking the part under the sieve to obtain calamine.

[0050] Example 2

[0051] Prepare the raw materials according to the following ratio:

[0052] 5 parts of alum, 10 parts of myrrh, 10 parts of frankincense, 30 parts of calamine, 5 parts of pearls, 5 parts of musk, 5 parts of plum tablets, and 2 parts of vermilion.

[0053] The composition of this embodiment was prepared as follows:

[0054] The alum, myrrh, frankincense, pearl, musk, and plum tablets are crushed, passed through a 150-mesh sieve, and the sieve portion is taken to obtain a medicinal powder;

[0055] S2, boiling honey until the honey juice is golden yellow to obtain honey juice, mixing the honey juice, the medicinal powder of step S1 and calamine, stirring evenly, making pills, and then coating the surface of the pills with silver vermilion. The mass ratio of the honey juice to the medicinal powder is 1:1.

[0056] Calamine in the present embodiment is obtained by the method for Example 1.

[0057] Example 3

[0058] Prepare the raw materials according to the following ratio:

[0059] 2 parts of alum, 6 parts of myrrh, 8 parts of frankincense, 30 parts of calamine, 3 parts of pearls, 2 parts of musk, 1 part of plum tablets, and 1.5 parts of vermilion.

[0060] The composition of this embodiment was prepared as follows:

[0061] The alum, myrrh, frankincense, pearl, musk, and plum tablets are crushed, passed through a 150-mesh sieve, and the sieve portion is taken to obtain a medicinal powder;

[0062] S2, boiling honey until the honey juice is golden yellow to obtain honey juice, mixing the honey juice, the medicinal powder of step S1 and calamine, stirring evenly, making pills, and then coating the surface of the pills with silver vermilion. The mass ratio of the honey juice to the medicinal powder is 1:1.

[0063] Calamine in the present embodiment is obtained by the method for Example 1.

[0064] Example 4

[0065] Prepare the raw materials according to the following ratio:

[0066] 1 part of alum, 10 parts of myrrh, 5 parts of frankincense, 20 parts of calamine, 1 part of pearl, 1 part of musk, 5 parts of plum tablets, and 1 part of vermilion.

[0067] The composition of this embodiment was prepared as follows:

[0068] The alum, myrrh, frankincense, pearl, musk, and plum tablets are crushed, passed through a 120-mesh sieve, and the sieve portion is taken to obtain a medicinal powder;

[0069] S2, boiling honey until the honey juice is golden yellow to obtain honey juice, mixing the honey juice, the medicinal powder of step S1 and calamine, stirring evenly, making pills, and then coating the surface of the pills with silver vermilion. The mass ratio of the honey juice to the medicinal powder is 1:1.

[0070] In this embodiment, the calamine used is prepared by the following method: crushing the block calamine, putting it into a container, adding water, and grinding it into a paste; adding water and stirring, standing for stratification, and pouring out the upper suspension; grinding the coarse particles in the lower layer again, repeating the operation, combining the suspension, standing, removing the upper clear liquid, drying, grinding into powder, passing through a 120-mesh sieve, and taking the undersize portion to obtain calamine.

[0071] Example 5

[0072] Prepare the raw materials according to the following ratio:

[0073] 5 parts of alum, 5 parts of myrrh, 8 parts of frankincense, 50 parts of calamine, 5 parts of pearls, 5 parts of musk, 5 parts of plum tablets, and 5 parts of vermilion.

[0074] The composition of this embodiment was prepared as follows:

[0075] The alum, myrrh, frankincense, pearl, musk, and plum tablets are crushed, passed through a 120-mesh sieve, and the sieve portion is taken to obtain a medicinal powder;

[0076] S2, boiling honey until the honey juice is golden yellow to obtain honey juice, mixing the honey juice, the medicinal powder of step S1 and calamine, stirring evenly, making pills, and then coating the surface of the pills with silver vermilion. The mass ratio of the honey juice to the medicinal powder is 1:1.

[0077] Calamine in the present embodiment is obtained by the method for Example 4.

[0078] Experimental example

[0079] 1. Clinical trials

[0080] 100 patients with dry eye were randomly selected and randomly divided into 2 groups. The experimental group used the composition of Example 1, an appropriate amount of cold boiled water-ground pills, applied to the eyelids, once in the morning and evening, and 15 days as a course of treatment. The control group was treated with sodium hyaluronate eye drops, 1 drop each time, 3 times a day. After 15 days of treatment, the number of cured, effective and ineffective patients in the experimental group and the control group was counted. The results are shown in Table 1.

[0081] It should be noted that the randomly selected patients were clinically diagnosed with dry eye and had no other diseases. The patients were aged 20-40 years old, excluding pregnant women.

[0082] The criteria for cure, effectiveness and ineffectiveness are

[0083] Cure: Eye symptoms disappear, tear secretion volume>10mm / 5min;

[0084] Effective: Eye symptoms are alleviated and relieved, tear secretion increases compared to before treatment, but still <10mm / 5min;

[0085] Ineffective: Eye symptoms did not improve or worsen, and tear secretion did not increase.

[0086] Table 1 Treatment effect

[0087] Heal (people) Effective (person) Invalid (person) Total effective rate (%) Experimental Group 41 7 2 96％ Control group 5 30 15 70％

[0088] It can be concluded from Table 1 that the total effective rate of the composition for treating dry eye provided in Example 1 can reach more than 90%, while the total effective rate of the control group is 70%, indicating that the composition provided by the present invention has an excellent therapeutic effect in treating dry eye.

[0089] 2. Typical Cases

[0090] (1) Li, 33 years old, often felt dry eyes, foreign body sensation, and burning sensation, which lasted for more than half a year. He relieved the symptoms by dropping artificial tears daily, and was clinically diagnosed with dry eyes. The drug provided in Example 1 was applied to the upper eyelid once a day in the morning and evening. After 15 days of continuous treatment, the foreign body sensation and burning sensation in the eyes disappeared, and the occasional dry eyes disappeared. After continuing to use the drug for 15 days, the dry eyes symptoms disappeared. There was no recurrence within half a year of follow-up.

[0091] (2) Jiang Moumou, 48 years old, often felt tired, sore, red and photophobia in the eyes for more than 1 year. He used artificial tears and sodium hyaluronate eye drops to relieve the symptoms. He was clinically diagnosed with dry eye. The drug provided in Example 1 was applied to the upper eyelid once a day in the morning and evening. After 20 days of continuous treatment, the symptoms of eye soreness and redness disappeared. After 15 days of continued medication, the eye symptoms disappeared. No recurrence was found during the follow-up of half a year.

[0092] In summary, the composition of the embodiment of the present invention, wherein alum is cold in nature, has the effects of clearing away heat and detoxicating, astringing and antiperspiring, and is the main medicine, which dominates the overall situation. Myrrh can promote blood circulation and remove blood stasis, while frankincense can promote qi and relieve pain. The two complement each other and assist the main medicine together to relieve the symptoms of dry eyes. Lu Ganshi clears heat and improves eyesight, pearl moisturizes and nourishes, musk promotes blood circulation and clears the orifices, and plum slices clear heat and detoxicate. The combination of all the medicines can not only restrict the coldness of the main medicine, but also enhance the efficacy and make the drug power more balanced. The above-mentioned raw materials cooperate with each other to treat dry eyes quickly and effectively.

[0093] The embodiments described above are part of the embodiments of the present invention, rather than all of the embodiments. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention claimed for protection, but merely represents selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

Claims

1. A composition for treating dry eye, characterized in that: The following raw materials are included by weight: 1-5 parts of alum, 5-10 parts of myrrh, 5-10 parts of frankincense, 20-50 parts of calamine, 1-5 parts of pearls, 1-5 parts of musk, 1-5 parts of plum tablets, and 1-2 parts of vermilion.

2. The composition for treating dry eye according to claim 1, characterized in that: The following raw materials are included by weight: 2 parts of alum, 6 parts of myrrh, 8 parts of frankincense, 30 parts of calamine, 3 parts of pearls, 2 parts of musk, 1 part of plum tablets, and 1.5 parts of vermilion.

3. The composition for treating dry eye according to claim 1, characterized in that: The following raw materials are included by weight: 5 parts of alum, 10 parts of myrrh, 10 parts of frankincense, 30 parts of calamine, 5 parts of pearls, 5 parts of musk, 5 parts of plum tablets, and 2 parts of vermilion.

4. The composition for treating dry eye according to claim 1, characterized in that: Described calamine is prepared by the following method: The calamine block is crushed, put into a container, and water is added, and the mixture is ground into a paste; water is then added and stirred, and the mixture is allowed to stand for stratification, and the upper suspension is poured out; the coarse particles in the lower layer are ground again, and the operation is repeated, and the suspension is combined, allowed to stand, the upper clear liquid is removed, and the mixture is dried and ground into powder to obtain the calamine.

5. The composition for treating dry eye according to claim 1, characterized in that: The particle size of the calamine is 120-150 meshes.

6. A method for preparing a composition for treating dry eye according to any one of claims 1 to 5, characterized in that: The following steps are involved: S1, crushing the alum, myrrh, frankincense, pearl, musk, and plum tablets to obtain medicinal powder; S2, boiling honey until it turns golden yellow to obtain honey juice, mixing the honey juice, the medicinal powder in step S1 and calamine, stirring evenly to make pills, and then coating the surface of the pills with vermilion.

7. The method for preparing the composition for treating dry eye according to claim 6, characterized in that: In the step S1, the particle size of the powder is 120-150 mesh.

8. The method for preparing the composition for treating dry eye according to claim 6, characterized in that: In the step S2, the mass ratio of the honey juice to the medicinal powder is 1:1.

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