Sterile surgical membrane and preparation method thereof

Abstract

The invention relates to the technical field of medical care systems, and discloses a sterile operation membrane and a preparation method thereof.The sterile operation membrane comprises an A-type sterile operation membrane and a B-type sterile operation membrane, the A-type sterile operation membrane is divided into an A1-type sterile operation membrane and an A2-type sterile operation membrane, and the B-type sterile operation membrane is divided into a B1-type sterile operation membrane and a B2-type sterile operation membrane. A1-type, A2-type, B1-type and B2-type sterile surgical membranes are selected, in the production process of the sterile surgical membranes, a stabilizer is added to enable the structure of the sterile surgical membranes to be more stable, an antioxidant is added to prevent the sterile surgical membranes from reacting with oxygen in air, then titanium dioxide and zinc oxide are added, and in the mixing process, antibacterial functional groups are introduced into the material, so that the antibacterial surgical membranes are prepared. Meanwhile, non-woven fabrics are arranged on the surfaces of the B1 type sterile surgical membrane and the B2 type sterile surgical membrane, so that the sterile surgical membrane can protect external bacteria.

Description

Technical Field

[0001] The invention relates to the technical field of medical care systems, in particular to a sterile surgical membrane and a preparation method thereof. Background Art

[0002] Surgical membrane is a medical film used to cover the surgical site during surgery to prevent contamination and infection in the surgical area. Surgical membrane is usually made of materials such as polypropylene or polyethylene, and has the characteristics of waterproof, blood-proof and bacterial-proof.

[0003] Existing surgical membranes have high requirements for blood penetration resistance and antibacterial properties. Therefore, the present application proposes a surgical membrane with high antibacterial properties. Summary of the invention

[0004] In view of the deficiencies in the prior art, the present invention provides a sterile surgical membrane and a preparation method thereof, which solves the problems raised in the above-mentioned background technology.

[0005] To solve the above technical problems, according to one aspect of the present invention, more specifically, a real-time monitoring system for vital signs of anesthetized patients is provided, comprising type A and type B sterile surgical membranes, wherein the type A sterile surgical membrane is divided into type A1 sterile surgical membrane and type A2 sterile surgical membrane, and the type B sterile surgical membrane is divided into type B1 sterile surgical membrane and type B2 sterile surgical membrane;

[0006] The main components of A1 sterile surgical film are: polyurethane, plasticizer, stabilizer, antioxidant, titanium dioxide and release paper;

[0007] The main components of A2 sterile surgical film are: polyethylene, plasticizer, stabilizer, antioxidant, zinc oxide and release paper;

[0008] The main components of B1 type sterile surgical membrane are: polyurethane, oxygenator, stabilizer, antioxidant, titanium dioxide, release paper and non-woven fabric;

[0009] The main components of type B2 sterile surgical film are: polyethylene, plasticizer, stabilizer, antioxidant, zinc oxide, release paper and non-woven fabric.

[0010] Furthermore, the main components of the sterile surgical membrane type A and type B are divided into the following by mass percentage:

[0011] A1 type sterile surgical film: polyurethane: 70-80%, plasticizer: 15-20%, stabilizer: 1-2%, antioxidant: 4-8%, titanium dioxide: 3-5%;

[0012] A2 type sterile surgical film: polyethylene: 70-80%, plasticizer: 15-20%, stabilizer: 1-2%, antioxidant: 5-10%, zinc oxide: 4-6%;

[0013] Type B1 sterile surgical membrane: polyurethane: 70-80%, plasticizer: 15-20%, stabilizer: 1-2%, antioxidant: 4-8%, titanium dioxide: 3-5%;

[0014] Type B2 sterile surgical film: polyethylene: 70-80%, plasticizer: 15-20%, stabilizer: 1-2%, antioxidant: 5-10%, zinc oxide: 4-6%.

[0015] Furthermore, the preparation method of the A1 type sterile surgical membrane comprises the following steps:

[0016] S1. Place polyurethane, plasticizer, stabilizer and antioxidant into a mixing device and mix at high speed for 10 to 20 minutes;

[0017] S2, placing titanium dioxide into a mixing device, and introducing the antibacterial functional groups into the material through high-temperature stirring;

[0018] S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes;

[0019] S4. Take out the material and place it on the surface of the release paper.

[0020] Furthermore, the preparation method of the A2 type sterile surgical membrane comprises the following steps:

[0021] S1. Place polyethylene, plasticizer, stabilizer and antioxidant into a mixing device and mix at high speed for 10 to 20 minutes;

[0022] S2, placing zinc oxide into a mixing device, and introducing the antibacterial functional groups into the material through high-temperature stirring;

[0023] S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes;

[0024] S4. Take out the material and place it on the surface of the release paper.

[0025] Furthermore, the preparation method of the B1 type sterile surgical membrane comprises the following steps:

[0026] S1. Place polyurethane, plasticizer, stabilizer and antioxidant into a mixing device and mix at high speed for 10 to 20 minutes;

[0027] S2, placing titanium dioxide into a mixing device, and introducing the antibacterial functional groups into the material through high-temperature stirring;

[0028] S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes;

[0029] S4, taking out the material and placing it on the surface of the release paper, and then covering the surface of the release paper with the non-woven fabric.

[0030] Furthermore, the preparation method of the B1 type sterile surgical membrane comprises the following steps:

[0031] S1. Place polyethylene, plasticizer, stabilizer and antioxidant into a mixing device and mix at high speed for 10 to 20 minutes;

[0032] S2, placing zinc oxide into a mixing device, and introducing the antibacterial functional groups into the material through high-temperature stirring;

[0033] S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes;

[0034] S4, taking out the material and placing it on the surface of the release paper, and then covering the surface of the release paper with the non-woven fabric.

[0035] Furthermore, after the sterile surgical membrane is produced, an antibacterial test is performed on it, and the calculation formula for the antibacterial rate of the sterile surgical membrane is:

[0036]

[0037] Where, θ is the antibacterial rate of the sterile surgical membrane; C is the concentration of live bacteria; B P is the average value of the number of colonies on the plate. At a certain dilution, the sample is evenly spread on the sterile culture medium plate. After a certain period of incubation, the average value of the number of colonies is obtained by counting; S is the dilution factor, which refers to the factor by which the sample is diluted with sterile water or other diluents before inoculation; V is the inoculation volume, which refers to the volume of the sample inoculated on the sterile culture medium plate, usually a fixed value; C1 is the average value of the live bacteria concentration in the control group, which refers to the average value of the number of live bacteria in the sample without the addition of sterile surgical film under certain conditions; C0 is the average value of the live bacteria concentration in the treatment group, which refers to the average value of the number of live bacteria in the sample with the addition of sterile surgical film under the same conditions; S1 is the number of live bacteria in the control group; S0 is the number of live bacteria in the treatment group.

[0038] Furthermore, the sterile surgical membrane is provided with support strips, a fluid collection bag and a PE backing according to clinical usage.

[0039] The beneficial effects of the sterile surgical membrane and the preparation method thereof of the present invention are:

[0040] The present invention selects A1 type, A2 type, B1 type and B2 type sterile surgical membranes according to clinical use conditions, and in the production process of the sterile surgical membranes, adds a stabilizer to make the structure of the sterile surgical membrane more stable, then adds an antioxidant to prevent the sterile surgical membrane from reacting with oxygen in the air, then adds titanium dioxide and zinc oxide, and in the mixing process, introduces antibacterial functional groups into the material to increase the antibacterial performance of the sterile surgical membrane, and at the same time, non-woven fabrics are arranged on the surfaces of the B1 type and B2 type sterile surgical membranes to increase the protection of the sterile surgical membranes against external bacteria. BRIEF DESCRIPTION OF THE DRAWINGS

[0041] The present invention is further described in detail below with reference to the accompanying drawings and specific implementation methods.

[0042] Figure 1 It is a schematic structural diagram of the A1 type sterile surgical membrane of the present invention.

[0043] Figure 2 It is a schematic structural diagram of the A2 type sterile surgical membrane of the present invention.

[0044] Figure 3 It is a schematic structural diagram of the B1 type sterile surgical membrane of the present invention.

[0045] Figure 4 It is a schematic structural diagram of the B2 type sterile surgical membrane of the present invention. DETAILED DESCRIPTION

[0046] The present invention will be described in detail below with reference to the accompanying drawings and in combination with embodiments. It should be noted that the embodiments and features in the embodiments of the present application can be combined with each other without conflict.

[0047] like Figure 1 As shown, according to one aspect of the present invention, a real-time monitoring system for vital signs of anesthetized patients is provided, comprising type A and type B sterile surgical membranes, wherein the type A sterile surgical membrane is divided into type A1 sterile surgical membrane and type A2 sterile surgical membrane, and the type B sterile surgical membrane is divided into type B1 sterile surgical membrane and type B2 sterile surgical membrane;

[0048] The main components of A1 sterile surgical film are: polyurethane, plasticizer, stabilizer, antioxidant, titanium dioxide and release paper;

[0049] The main components of A2 sterile surgical film are: polyethylene, plasticizer, stabilizer, antioxidant, zinc oxide and release paper;

[0050] The main components of B1 type sterile surgical membrane are: polyurethane, oxygenator, stabilizer, antioxidant, titanium dioxide, release paper and non-woven fabric;

[0051] The main components of type B2 sterile surgical film are: polyethylene, plasticizer, stabilizer, antioxidant, zinc oxide, release paper and non-woven fabric.

[0052] In this embodiment, the main components of the sterile surgical membrane type A and type B are divided into the following types by weight percentage:

[0053] A1 type sterile surgical film: polyurethane: 70-80%, plasticizer: 15-20%, stabilizer: 1-2%, antioxidant: 4-8%, titanium dioxide: 3-5%;

[0054] A2 type sterile surgical film: polyethylene: 70-80%, plasticizer: 15-20%, stabilizer: 1-2%, antioxidant: 5-10%, zinc oxide: 4-6%;

[0055] Type B1 sterile surgical membrane: polyurethane: 70-80%, plasticizer: 15-20%, stabilizer: 1-2%, antioxidant: 4-8%, titanium dioxide: 3-5%;

[0056] Type B2 sterile surgical film: polyethylene: 70-80%, plasticizer: 15-20%, stabilizer: 1-2%, antioxidant: 5-10%, zinc oxide: 4-6%.

[0057] In this embodiment, the preparation method of the A1 type sterile surgical membrane comprises the following steps:

[0058] S1. Place polyurethane, plasticizer, stabilizer and antioxidant into a mixing device and mix at high speed for 10 to 20 minutes;

[0059] S2, placing titanium dioxide into a mixing device, and introducing the antibacterial functional groups into the material through high-temperature stirring;

[0060] S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes;

[0061] S4. Take out the material and place it on the surface of the release paper.

[0062] In this embodiment, the preparation method of the A2 type sterile surgical membrane comprises the following steps:

[0063] S1. Place polyethylene, plasticizer, stabilizer and antioxidant into a mixing device and mix at high speed for 10 to 20 minutes;

[0064] S2, placing zinc oxide into a mixing device, and introducing the antibacterial functional groups into the material through high-temperature stirring;

[0065] S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes;

[0066] S4. Take out the material and place it on the surface of the release paper.

[0067] In this embodiment, the method for preparing the B1 type sterile surgical membrane comprises the following steps:

[0068] S1. Place polyurethane, plasticizer, stabilizer and antioxidant into a mixing device and mix at high speed for 10 to 20 minutes;

[0069] S2, placing titanium dioxide into a mixing device, and introducing the antibacterial functional groups into the material through high-temperature stirring;

[0070] S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes;

[0071] S4, taking out the material and placing it on the surface of the release paper, and then covering the surface of the release paper with the non-woven fabric.

[0072] In this embodiment, the method for preparing the B1 type sterile surgical membrane comprises the following steps:

[0073] S1. Place polyethylene, plasticizer, stabilizer and antioxidant into a mixing device and mix at high speed for 10 to 20 minutes;

[0074] S2, placing zinc oxide into a mixing device, and introducing the antibacterial functional groups into the material through high-temperature stirring;

[0075] S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes;

[0076] S4, taking out the material and placing it on the surface of the release paper, and then covering the surface of the release paper with the non-woven fabric.

[0077] In this embodiment, after the sterile surgical membrane is produced, an antibacterial test is performed on it. The calculation formula for the antibacterial rate of the sterile surgical membrane is:

[0078]

[0079] Where, θ is the antibacterial rate of the sterile surgical membrane; C is the concentration of live bacteria; B Pis the average value of the number of colonies on the plate. At a certain dilution, the sample is evenly spread on the sterile culture medium plate. After a certain period of incubation, the average value of the number of colonies is obtained by counting; S is the dilution factor, which refers to the factor by which the sample is diluted with sterile water or other diluents before inoculation; V is the inoculation volume, which refers to the volume of the sample inoculated on the sterile culture medium plate, usually a fixed value; C1 is the average value of the live bacteria concentration in the control group, which refers to the average value of the number of live bacteria in the sample without the addition of sterile surgical film under certain conditions; C0 is the average value of the live bacteria concentration in the treatment group, which refers to the average value of the number of live bacteria in the sample with the addition of sterile surgical film under the same conditions; S1 is the number of live bacteria in the control group; S0 is the number of live bacteria in the treatment group.

[0080] In this embodiment, the sterile surgical membrane is provided with support strips, a fluid collection bag and a PE backing according to clinical usage.

[0081] Example 1

[0082] S1. Place 70-80% polyurethane, 15-20% plasticizer, 1-2% stabilizer and 4-8% antioxidant into a mixing device and mix at high speed for 10-20 minutes;

[0083] S2, placing 3-5% titanium dioxide into a mixing device, and introducing the antibacterial functional groups into the material through high-temperature stirring;

[0084] S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes;

[0085] S4. Take out the material and place it on the surface of the release paper.

[0086] Example 2

[0087] S1. Place 70-80% polyethylene, 15-20% plasticizer, 1-2% stabilizer and 5-10% antioxidant into a mixing device and mix at high speed for 10-20 minutes;

[0088] S2. Place 4-6% zinc oxide into a mixing device and introduce the antibacterial functional groups into the material through high-temperature stirring;

[0089] S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes;

[0090] S4. Take out the material and place it on the surface of the release paper.

[0091] Example 3

[0092] S1. Place 70-80% polyurethane, 15-20% plasticizer, 1-2% stabilizer and 4-8% antioxidant into a mixing device and mix at high speed for 10-20 minutes;

[0093] S2, placing 3-5% titanium dioxide into a mixing device, and introducing the antibacterial functional groups into the material through high-temperature stirring;

[0094] S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes;

[0095] S4, taking out the material and placing it on the surface of the release paper, and then covering the surface of the release paper with the non-woven fabric.

[0096] Example 4

[0097] S1. Place 70-80% polyethylene, 15-20% plasticizer, 1-2% stabilizer and 5-10% antioxidant into a mixing device and mix at high speed for 10-20 minutes;

[0098] S2. Place 4-6% zinc oxide into a mixing device and introduce the antibacterial functional groups into the material through high-temperature stirring;

[0099] S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes;

[0100] S4, taking out the material and placing it on the surface of the release paper, and then covering the surface of the release paper with the non-woven fabric.

[0101] The data of the viscosity, tensile strength, water vapor transmission rate, peel strength and antibacterial rate of the sterile surgical membrane obtained according to Examples 1, 2, 3 and 4 are as follows

[0102]

[0103]

[0104] Of course, the above description is not a limitation of the present invention, and the present invention is not limited to the above examples. Changes, modifications, additions or substitutions made by ordinary technicians in this technical field within the essential scope of the present invention also fall within the protection scope of the present invention.

Claims

1. A sterile surgical membrane, comprising type A and type B sterile surgical membranes, wherein the type A sterile surgical membrane is divided into type A1 sterile surgical membrane and type A2 sterile surgical membrane, and the type B sterile surgical membrane is divided into type B1 sterile surgical membrane and type B2 sterile surgical membrane; The main components of A1 sterile surgical film are: polyurethane, plasticizer, stabilizer, antioxidant, titanium dioxide and release paper; The main components of A2 sterile surgical film are: polyethylene, plasticizer, stabilizer, antioxidant, zinc oxide and release paper; The main components of B1 type sterile surgical membrane are: polyurethane, oxygenator, stabilizer, antioxidant, titanium dioxide, release paper and non-woven fabric; The main components of type B2 sterile surgical film are: polyethylene, plasticizer, stabilizer, antioxidant, zinc oxide, release paper and non-woven fabric.

2. A sterile surgical membrane according to claim 1, characterized in that: The main components of the sterile surgical membrane type A and type B are divided into the following by mass percentage: A1 type sterile surgical film: polyurethane: 70-80%, plasticizer: 15-20%, stabilizer: 1-2%, antioxidant: 4-8%, titanium dioxide: 3-5%; A2 type sterile surgical film: polyethylene: 70-80%, plasticizer: 15-20%, stabilizer: 1-2%, antioxidant: 5-10%, zinc oxide: 4-6%; Type B1 sterile surgical membrane: polyurethane: 70-80%, plasticizer: 15-20%, stabilizer: 1-2%, antioxidant: 4-8%, titanium dioxide: 3-5%; Type B2 sterile surgical film: polyethylene: 70-80%, plasticizer: 15-20%, stabilizer: 1-2%, antioxidant: 5-10%, zinc oxide: 4-6%.

3. The method for preparing a sterile surgical membrane according to claim 1, characterized in that: The preparation method of the A1 type sterile surgical membrane comprises the following steps: S1. Place polyurethane, plasticizer, stabilizer and antioxidant into a mixing device and mix at high speed for 10 to 20 minutes; S2, placing titanium dioxide into a mixing device, and introducing the antibacterial functional groups into the material through high-temperature stirring; S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes; S4. Take out the material and place it on the surface of the release paper.

4. A sterile surgical membrane and a method for preparing the same according to claim 1, characterized in that: The preparation method of the A2 type sterile surgical membrane comprises the following steps: S1. Place polyethylene, plasticizer, stabilizer and antioxidant into a mixing device and mix at high speed for 10 to 20 minutes; S2, placing zinc oxide into a mixing device, and introducing the antibacterial functional groups into the material through high-temperature stirring; S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes; S4. Take out the material and place it on the surface of the release paper.

5. A sterile surgical membrane and a method for preparing the same according to claim 1, characterized in that: The preparation method of the B1 type sterile surgical membrane comprises the following steps: S1. Place polyurethane, plasticizer, stabilizer and antioxidant into a mixing device and mix at high speed for 10 to 20 minutes; S2, placing titanium dioxide into a mixing device, and introducing the antibacterial functional groups into the material through high-temperature stirring; S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes; S4, taking out the material and placing it on the surface of the release paper, and then covering the surface of the release paper with the non-woven fabric.

6. A sterile surgical membrane and a method for preparing the same according to claim 1, characterized in that: The preparation method of the B1 type sterile surgical membrane comprises the following steps: S1. Place polyethylene, plasticizer, stabilizer and antioxidant into a mixing device and mix at high speed for 10 to 20 minutes; S2, placing zinc oxide into a mixing device, and introducing the antibacterial functional groups into the material through high-temperature stirring; S3, pouring the mixed solution into an injection molding machine, applying the solution to the surface of the hypoallergenic pressure-sensitive adhesive through the injection molding machine, and placing it in a sterile processing device for 30 minutes; S4, taking out the material and placing it on the surface of the release paper, and then covering the surface of the release paper with the non-woven fabric.

7. The method for preparing a sterile surgical membrane according to claim 1, characterized in that: After the sterile surgical membrane is produced, it is subjected to antibacterial testing. The calculation formula for the antibacterial rate of the sterile surgical membrane is: Where, θ is the antibacterial rate of the sterile surgical membrane; C is the concentration of live bacteria; B P is the average value of the number of colonies on the plate. At a certain dilution, the sample is evenly spread on the sterile culture medium plate. After a certain period of incubation, the average value of the number of colonies is obtained by counting; S is the dilution factor, which refers to the factor by which the sample is diluted with sterile water or other diluents before inoculation; V is the inoculation volume, which refers to the volume of the sample inoculated on the sterile culture medium plate, usually a fixed value; C1 is the average value of the live bacteria concentration in the control group, which refers to the average value of the number of live bacteria in the sample without the addition of sterile surgical film under certain conditions; C0 is the average value of the live bacteria concentration in the treatment group, which refers to the average value of the number of live bacteria in the sample with the addition of sterile surgical film under the same conditions; S1 is the number of live bacteria in the control group; S0 is the number of live bacteria in the treatment group.

8. The method for preparing a sterile surgical membrane according to claim 1, characterized in that: The sterile surgical membrane is provided with support strips, a fluid collection bag and a PE backing according to clinical use conditions.

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