Blood post-treatment cup distribution system and method
Patent Information
- Application Number
- CN202411497393.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-25
- Publication Date
- 2025-01-28
AI Technical Summary
The traditional blood post-processing process relies on manual operations, which is time-consuming and labor-intensive, and has the risk of human error, affects the accuracy and efficiency of the processing results, and is difficult to meet the high-throughput and high-efficiency processing needs.
A post -cup system is designed, including the robotic arm of the vascular clip bottle, the pipette mechanical arm, the vascular coding module, the serum liquid surface recognition module, etc., through automated equipment to realize the rapid clip of vascular mining and frozen storage tube. Take, move, open the lid, read code, pipette, and packaging and other operations.
The automation of post -blood treatment is realized, the processing speed and efficiency are improved, the human error is reduced, the accuracy of the sample information and the accuracy of the amount of the sample information meets the demand for high -throughput processing.
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Figure CN119374984A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of blood processing equipment, and in particular to a blood post-processing cup-dispensing system and method. Background Art
[0002] In the field of medical testing and scientific research, the processing of blood samples is a vital task. The traditional blood post-processing process, including the clamping of blood collection tubes, opening of the cap, code reading, identification of serum level, pipetting and packaging, mostly relies on manual operation, which is not only time-consuming and labor-intensive, but also has the risk of human error, affecting the accuracy and efficiency of the processing results. Especially when processing a large number of samples, the limitations of manual operation are particularly obvious, and it is difficult to meet the needs of high-throughput and high-efficiency processing.
[0003] In addition, traditional processing methods also have many shortcomings in terms of sterile environment and sample safety. For example, it is difficult to completely avoid cross-contamination in manual operations, and the tracking and management of samples lacks systematicity and accuracy. With the continuous advancement of medical technology and the growing demand for scientific research, it is particularly important to develop an automated, efficient, and low-error blood post-processing cupping system and method. Summary of the invention
[0004] The purpose of the present invention is to provide a blood post-processing and cupping system and method to solve the problem that the traditional blood post-processing process proposed in the above background technology, including the steps of clamping, opening the cover, reading the code, identifying the serum liquid level, pipetting and packaging of the blood collection tube, mostly relies on manual operation, which is not only time-consuming and labor-intensive, but also has the risk of human error, affecting the accuracy and efficiency of the processing results.
[0005] To achieve the above-mentioned purpose, the present invention provides a blood post-processing cupping system and method, comprising a shell, a blood collection tube bottle clamping robot arm is installed inside the shell, a blood collection tube code reading module is installed on the blood collection tube bottle clamping robot arm, a blood collection tube cover opening module is installed at the end of the blood collection tube bottle clamping robot arm, a blood collection tube fixture is arranged at the lower part of the shell, a serum liquid level recognition module is arranged on one side of the blood collection tube fixture, an abnormal tube box is arranged on the other side of the blood collection tube fixture, a suction head is installed on one side of the abnormal tube box, and a waste port is arranged at the bottom of the shell near the abnormal tube box.
[0006] As a preferred embodiment of the present invention, the blood collection tube clamping robot arm is equipped with an XYZ three-dimensional moving module and parallel clamping claws, which are used to clamp the blood collection tube from the blood collection tube rack and move it to a designated position.
[0007] As a preferred solution of the present invention, the blood collection tube code reading module includes a code scanner.
[0008] As a preferred solution of the present invention, the blood collection tube cover opening module is a rotating clamping claw for clamping and opening the blood collection tube cover.
[0009] As a preferred embodiment of the present invention, a cryogenic tube fixture is also installed inside the shell, a cryogenic tube code reading module is installed on one side of the cryogenic tube fixture, a cryogenic tube cover opening module is installed on the upper part of the cryogenic tube fixture, and the cryogenic tube fixture has an R rotation module for supporting and rotating the cryogenic tubes for different operations. The cryogenic tube code reading module is configured with two barcode scanners for scanning and identifying the cryogenic tubes and their packaging boxes.
[0010] As a preferred solution of the present invention, a liquid transfer robot is installed on the upper side of the housing, an air filter and an ultraviolet lamp are installed on the inner side of the top of the housing, and an observation window is installed on the front side of the housing.
[0011] As a preferred solution of the present invention, the cryotube lid opening module has a YZ moving module and an R rotating Z lid removing module, which are used to open the cryotube lid.
[0012] As a preferred embodiment of the present invention, the serum level recognition module includes a camera and a light source, wherein the light sources are three in number; the module is used to capture and identify the position of the serum in the blood collection tube, and output the serum height and volume information.
[0013] As a preferred embodiment of the present invention, the liquid transfer robot arm is equipped with an XY two-dimensional moving module and a Z-axis R-direction liquid aspiration and exhalation module, which are used to aspirate serum from the blood collection tube and dispense it into cryopreservation tubes.
[0014] The present invention also provides a blood post-processing cupping method, which is used in the blood post-processing cupping system, and comprises the following steps:
[0015] S1. Blood collection tube processing flow: the blood collection tube clamping arm clamps the blood collection tube from the blood collection tube rack and moves it to the top of the rotating clamping claw. After the rotating clamping claw is clamped, the parallel clamping claw is released; the rotating clamping claw rotates so that the barcode scanner can scan the code successfully; then it rotates a certain angle to facilitate the camera and light source to identify the serum height, output the upper and lower liquid levels of the serum, convert the height into the Z-axis stroke, and convert the volume into the amount of liquid aspirated. After waiting for the pipetting arm to complete the aspiration operation, the cover is put on and the blood collection tube is put back in place;
[0016] S2, serum pipetting and subpackaging process: After the pipetting arm takes the tip, it goes to the blood collection tube to absorb serum, moves to the subpackaging position of the cryopreservation tube turntable, and subpacks according to the subpackaging quantity; each time a cryopreservation tube is subpacked, the blood collection tube code, cryopreservation tube box code, and cryopreservation tube code are bound and output, and then the tip is moved to the waste port to be discarded;
[0017] S3, cryotube processing flow: the cryotube turntable turns the cryotube to the cover opening position, and the cryotube cover opening arm opens a row of 8 cryotube covers at the same time each time; first read the code to determine whether there are cryotubes placed in this plate position, and then open the cover and wait for the pipetting arm to load; after all 8 cryotubes in a row are loaded, the turntable turns back to the cover opening position, and the cover opening arm performs the cover operation, and then the next row of cover opening is processed;
[0018] S4. Parallel processing capability: The above-mentioned blood collection tube processing process, serum pipetting and packaging process, and cryopreservation tube processing process can be carried out simultaneously to improve the overall processing efficiency of the system.
[0019] Compared with the prior art, the present invention has the following beneficial effects:
[0020] 1. In the blood post-processing cup-dispensing system and method, through the use of automated equipment such as blood collection tube bottle clamping robot arms and liquid transfer robot arms, operations such as rapid clamping, movement, cap opening, code reading, liquid transfer and dispensing of blood collection tubes and cryopreservation tubes are realized, which greatly improves the processing speed and meets the needs of high-throughput processing.
[0021] 2. In the blood post-processing cupping system and method, the precise identification of the blood collection tube code reading module and the cryopreservation tube code reading module, as well as the precise measurement of the serum liquid level identification module, ensure the accuracy of the sample information and the accuracy of the cupping quantity, and improve the reliability of the processing results.
[0022] 3. In the blood post-processing cupping system and method, the fully automated process reduces human intervention, thereby reducing errors and mistakes caused by human factors and improving the stability and consistency of the processing process.
[0023] 4. In the blood post-processing cupping system and method, the air filter and ultraviolet lamp inside the shell effectively purify the working environment and reduce the risk of microbial contamination; at the same time, the system's tracking and management of samples is more systematic and accurate, ensuring the safety and traceability of the samples.
[0024] 5. In the blood post-processing and cupping system and method, the blood collection tube processing process, serum pipetting and packaging process, and cryopreservation tube processing process can be carried out simultaneously, further improving the overall processing efficiency of the system and meeting the needs of scientific research and medical testing fields for efficient processing. BRIEF DESCRIPTION OF THE DRAWINGS
[0025] Figure 1 It is a front structural schematic diagram of the present invention;
[0026] Figure 2 It is a schematic diagram of the top view structure of the present invention;
[0027] Figure 3 It is a schematic diagram of the external structure of the present invention;
[0028] The meaning of each number in the figure is:
[0029] 1. Shell; 101. Observation window; 2. Air filter; 3. Ultraviolet lamp; 4. Blood collection tube bottle clamping robot arm; 5. Blood collection tube code reading module; 6. Serum liquid level recognition module; 61. Shooting camera; 62. Light source; 7. Blood collection tube fixture; 8. Abnormal tube box; 9. Pipette tip; 10. Cryo tube fixture; 11. Waste port; 12. Cryo tube code reading module; 13. Liquid transfer robot arm; 14. Cryo tube cover opening module; 15. Blood collection tube cover opening module. DETAILED DESCRIPTION
[0030] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0031] The present invention provides a blood post-processing cup-dispensing system, such as Figure 1-Figure 3 As shown, it includes a shell 1, a blood collection tube bottle clamping mechanical arm 4 is installed inside the shell 1, a blood collection tube code reading module 5 is installed on the blood collection tube bottle clamping mechanical arm 4, a blood collection tube cover opening module 15 is installed at the end of the blood collection tube bottle clamping mechanical arm 4, a blood collection tube fixture 7 is arranged at the lower part of the shell 1, a serum liquid level identification module 6 is arranged on one side of the blood collection tube fixture 7, an abnormal tube box 8 is arranged on the other side of the blood collection tube fixture 7, a suction head 9 is installed on one side of the abnormal tube box 8, and a waste port 11 is arranged at the bottom of the shell 1 near the abnormal tube box 8. The system cleverly arranges the blood collection tube bottle clamping mechanical arm 4 and its attached code reading module 5 and cover opening module 15 inside the shell 1, and these designs together realize the rapid and accurate clamping, movement, code reading and cover opening operations of the blood collection tube. At the same time, the blood collection tube fixture 7 arranged below the shell 1 provides a stable support platform for the blood collection tube, which is convenient for subsequent processing.
[0032] The introduction of serum level recognition module 6 enables the system to accurately identify the position of serum in the blood collection tube, thereby accurately outputting serum height and distribution volume information, providing a reliable basis for subsequent pipetting and packaging operations. The setting of abnormal tube box 8 effectively copes with abnormal blood collection tubes that may appear during the processing process, ensuring the smooth progress of the entire processing flow.
[0033] In addition, the pipette tip 9 installed on one side of the abnormal tube box 8 and the waste port 11 at the bottom of the housing 1 near the abnormal tube box 8 further optimize the operation process of the system, reduce manual intervention, and improve processing efficiency. The convenient use of the pipette tip 9 makes the pipetting operation more efficient; the reasonable setting of the waste port 11 ensures the timely discharge of waste and keeps the working environment clean.
[0034] In this embodiment, the blood collection tube clamping robot arm 4 is equipped with an XYZ three-dimensional moving module and parallel clamping claws, which are used to clamp blood collection tubes from the blood collection tube rack and move them to a specified position. This design enables the robot arm to accurately clamp blood collection tubes from the blood collection tube rack and move them to a specified position quickly and accurately. This three-dimensional movement capability greatly improves the flexibility and efficiency of blood collection tube processing and ensures the smooth progress of subsequent operations.
[0035] Specifically, the blood collection tube code reading module 5 includes a code scanner. This design ensures rapid identification of sample information, provides reliable data support for subsequent serum level identification, pipetting and packaging operations, and improves the accuracy and efficiency of the entire processing flow.
[0036] Furthermore, the blood collection tube opening module 15 is a rotating clamping claw, which is used to clamp and open the blood collection tube cover. This design avoids errors and contamination that may occur when opening the cover manually, ensures the accuracy and sterility of the opening operation, and provides safety for subsequent serum processing.
[0037] Furthermore, a cryogenic tube fixture 10 is installed inside the shell 1, a cryogenic tube code reading module 12 is installed on one side of the cryogenic tube fixture 10, a cryogenic tube cover opening module 14 is installed on the upper part of the cryogenic tube fixture 10, and the cryogenic tube fixture 10 has an R rotation module for supporting and rotating the cryogenic tube for different operations. The cryogenic tube code reading module 12 is configured with two barcode scanners for scanning and identifying the cryogenic tubes and their packaging boxes.
[0038] Furthermore, the housing 1 is provided with a liquid transfer robot 13 on the top, an air filter 2 and an ultraviolet lamp 3 are installed on the inner side of the top of the housing 1, and an observation window 101 is installed on the front of the housing 1. Together, they form an efficient and sterile working environment. The air filter 2 can effectively remove microorganisms and impurities in the air to keep the working environment clean; the ultraviolet lamp 3 can kill residual microorganisms to ensure aseptic operation. At the same time, the observation window 101 installed on the front of the housing 1 is convenient for the operator to observe the internal working conditions at any time, ensuring the controllability and safety of the system.
[0039] Furthermore, the cryotube cover opening module 14 has a YZ moving module and an R rotating Z cover removing module for opening the cryotube cover. This design makes the cover opening operation more accurate and stable. Through the coordinated work of the YZ moving module and the R rotating Z cover removing module, the cryotube cover can be accurately opened, avoiding errors and contamination during the cover opening process, and ensuring the smooth progress of subsequent operations.
[0040] Furthermore, the serum level recognition module 6 includes a camera 61 and a light source 62, and the number of light sources 62 is three; it is used to capture and identify the position of the serum in the blood collection tube, and output the serum height and the amount of blood to be divided. This design can clearly capture and identify the position of the serum in the blood collection tube. Through the reasonable layout of the light source and the precise shooting of the camera, the serum height and the amount of blood to be divided can be accurately output, providing reliable data support for subsequent pipetting and subpackaging operations, and improving the accuracy and efficiency of the entire processing flow.
[0041] Furthermore, the liquid transfer robot 13 is equipped with an XY two-dimensional moving module and a Z-axis R-direction liquid suction and discharge module, which are used to draw serum from the blood collection tube and dispense it into cryopreservation tubes. This design enables the robot to accurately draw serum from the blood collection tube and dispense it into cryopreservation tubes. Through the coordinated work of the XY two-dimensional moving module and the Z-axis R-direction liquid suction and discharge module, the accuracy and stability of the liquid transfer operation can be ensured, errors and contamination in the liquid transfer process can be avoided, and the efficiency and accuracy of the entire processing flow can be improved.
[0042] The present invention also provides a blood post-processing cupping method for use in a blood post-processing cupping system, which is characterized by comprising the following steps:
[0043] S1. Blood collection tube processing flow: the blood collection tube clamping arm clamps the blood collection tube from the blood collection tube rack and moves it to the top of the rotating clamping claw. After the rotating clamping claw is clamped, the parallel clamping claw is released; the rotating clamping claw rotates so that the barcode scanner can scan the code successfully; then it rotates a certain angle to facilitate the camera and light source to identify the serum height, output the upper and lower liquid levels of the serum, convert the height into the Z-axis stroke, and convert the volume into the amount of liquid aspirated. After waiting for the pipetting arm to complete the aspiration operation, the cover is put on and the blood collection tube is put back in place;
[0044] S2, serum pipetting and subpackaging process: After the pipetting arm takes the tip, it goes to the blood collection tube to absorb serum, moves to the subpackaging position of the cryopreservation tube turntable, and subpacks according to the subpackaging quantity; each time a cryopreservation tube is subpacked, the blood collection tube code, cryopreservation tube box code, and cryopreservation tube code are bound and output, and then the tip is moved to the waste port to be discarded;
[0045] S3, cryotube processing flow: the cryotube turntable turns the cryotube to the cover opening position, and the cryotube cover opening arm opens a row of 8 cryotube covers at the same time each time; first read the code to determine whether there are cryotubes placed in this plate position, and then open the cover and wait for the pipetting arm to load; after all 8 cryotubes in a row are loaded, the turntable turns back to the cover opening position, and the cover opening arm performs the cover operation, and then the next row of cover opening is processed;
[0046] S4. Parallel processing capability: The above-mentioned blood collection tube processing process, serum pipetting and packaging process, and cryopreservation tube processing process can be carried out simultaneously to improve the overall processing efficiency of the system.
[0047] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments. The above embodiments and descriptions are only preferred examples of the present invention and are not intended to limit the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention. The scope of protection of the present invention is defined by the attached claims and their equivalents.
Claims
1. A blood post-processing cup-dispensing system, comprising a housing (1), characterized in that: A blood collection tube bottle clamping mechanical arm (4) is installed inside the shell (1), a blood collection tube code reading module (5) is installed on the blood collection tube bottle clamping mechanical arm (4), a blood collection tube cover opening module (15) is installed at the end of the blood collection tube bottle clamping mechanical arm (4), a blood collection tube fixture (7) is arranged at the lower part of the shell (1), a serum liquid level recognition module (6) is arranged on one side of the blood collection tube fixture (7), an abnormal tube box (8) is arranged on the other side of the blood collection tube fixture (7), a suction head (9) is installed on one side of the abnormal tube box (8), and a waste port (11) is arranged at the bottom of the shell (1) near the abnormal tube box (8).
2. The blood post-processing cup-dispensing system according to claim 1, characterized in that: The blood collection tube clamping mechanical arm (4) is equipped with an XYZ three-dimensional moving module and parallel clamping claws, and is used to clamp the blood collection tube from the blood collection tube rack and move it to a designated position.
3. The blood post-processing cup-dispensing system according to claim 1, characterized in that: The blood collection tube code reading module (5) comprises a code scanner.
4. The blood post-processing cup-dispensing system according to claim 1, characterized in that: The blood collection tube cover opening module (15) is a rotating clamping claw used for clamping and opening the blood collection tube cover.
5. The blood post-processing cup-dispensing system according to claim 1, characterized in that: A cryotube jig (10) is also installed inside the shell (1), a cryotube code reading module (12) is installed on one side of the cryotube jig (10), a cryotube cover opening module (14) is installed on the upper part of the cryotube jig (10), the cryotube jig (10) is provided with an R rotation module for supporting and rotating the cryotube to facilitate different operations, and the cryotube code reading module (12) is equipped with two code scanners for scanning and identifying the cryotube and its packaging box.
6. The blood post-processing cup-dispensing system according to claim 1, characterized in that: The housing (1) is internally installed with a liquid transfer robot arm (13) arranged on the top, an air filter (2) and an ultraviolet lamp (3) are installed on the inner side of the top of the housing (1), and an observation window (101) is installed on the front of the housing (1).
7. The blood post-processing cupping system and method according to claim 5, characterized in that: The cryotube cover opening module (14) comprises a YZ moving module and an R rotating Z cover removing module, and is used for opening the cryotube cover.
8. The blood post-processing cup-dispensing system according to claim 1, characterized in that: The serum level recognition module (6) comprises a shooting camera (61) and a light source (62), wherein the number of the light sources (62) is three; and is used to shoot and identify the position of the serum in the blood collection tube, and output serum height and volume information.
9. The blood post-processing cup-dispensing system according to claim 6, characterized in that: The liquid transfer robot (13) is provided with an XY two-dimensional moving module and a Z-axis R-direction liquid suction and discharge module, and is used for sucking serum from the blood collection tube and dispensing it into cryopreservation tubes.
10. A method for post-processing blood into cups, characterized in that: The blood post-processing cup-dispensing system according to claims 1 to 9 is characterized in that it comprises the following steps: S1. Blood collection tube processing flow: the blood collection tube clamping arm clamps the blood collection tube from the blood collection tube rack and moves it to the top of the rotating clamping claw. After the rotating clamping claw is clamped, the parallel clamping claw is released; the rotating clamping claw rotates so that the barcode scanner can scan the code successfully; then it rotates a certain angle to facilitate the camera and light source to identify the serum height, output the upper and lower liquid levels of the serum, convert the height into the Z-axis stroke, and convert the volume into the amount of liquid aspirated. After waiting for the pipetting arm to complete the aspiration operation, the cover is put on and the blood collection tube is put back in place; S2, serum pipetting and subpackaging process: After the pipetting arm takes the tip, it goes to the blood collection tube to absorb serum, moves to the subpackaging position of the cryopreservation tube turntable, and subpacks according to the subpackaging quantity; each time a cryopreservation tube is subpacked, the blood collection tube code, cryopreservation tube box code, and cryopreservation tube code are bound and output, and then the tip is moved to the waste port to be discarded; S3, cryotube processing flow: the cryotube turntable turns the cryotube to the cover opening position, and the cryotube cover opening arm opens a row of 8 cryotube covers at the same time each time; first read the code to determine whether there are cryotubes placed in this plate position, and then open the cover and wait for the pipetting arm to load; after all 8 cryotubes in a row are loaded, the turntable turns back to the cover opening position, and the cover opening arm performs the cover operation, and then the next row of cover opening is processed; S4. Parallel processing capability: The above-mentioned blood collection tube processing process, serum pipetting and packaging process, and cryopreservation tube processing process can be carried out simultaneously to improve the overall processing efficiency of the system.