Multi-hole-site cooperative operation anti-cross infection type sample pretreatment instrument

Abstract

A multi-hole-site cooperative operation cross infection prevention type sample pretreatment instrument comprises an industrial personal computer, a three-axis driving mechanical module, a stirring structure and a clamping structure, and relates to the technical field of sample treatment, the right side wall of the industrial personal computer is provided with an exhaust fan, the left side wall of the industrial personal computer is provided with an air inlet fan, and the right side of the front end of the industrial personal computer is provided with an observation window; according to the invention, the plurality of sample extraction tanks, the solid-phase extraction pipe and the liquid concentrator cooperate with one another to work, so that twelve samples can be treated at the same time, and the problem of cross contamination of the samples caused by using one liquid adding and washing liquid pipeline is prevented; the fastening connection of the top cover and the sample extraction tank is completed through the mutual cooperation of the clamping block and the clamping groove, so that the influence on stirring caused by shaking of the top cover when a sample is stirred by the transmission shaft is prevented, and the treatment efficiency is further improved; the interior of the industrial personal computer is ventilated through the exhaust fan and the air inlet fan, and waste gas generated in the industrial personal computer is exhausted into an external ventilation and purification device through the exhaust fan.

Description

Technical Field

[0001] The invention relates to the technical field of sample processing, and in particular to a cross-infection-proof sample pre-processing instrument with coordinated operation of multiple holes. Background Art

[0002] Sample pretreatment is usually the first step of analysis. The result of this step will affect the subsequent analysis process. For sample pretreatment, it refers to a series of processing steps to prepare the sample before further analysis. The specific steps and methods of sample pretreatment will vary according to different analysis requirements and sample types. According to the analysis requirements, the sample is pretreated by steps such as crushing, grinding, filtering, diluting, etc. to obtain a sample that meets the analysis requirements.

[0003] When diluting and stirring the sample, the sample in the sample tube needs to be stirred. Usually, a stirring structure is installed on the top cover of the sample tube. During the stirring process, the connection between the top cover of the sample tube and the sample tube is unstable, which can easily cause the stirring rod to shake, thereby affecting the dilution effect. When handling odorous and corrupted samples, harmful gases are easily generated, which affects the health of the operator. In order to solve the above problems, this application proposes a cross-infection-proof sample pre-treatment instrument with multi-hole position cooperation operation. Summary of the invention

[0004] The present invention provides a cross-infection-proof sample pre-treatment instrument with coordinated operation of multiple holes to solve the technical problems existing in the background technology.

[0005] In order to solve the above problems, the present invention proposes a cross-infection prevention sample preprocessing instrument with multi-hole position cooperation operation, including an industrial computer, a three-axis drive mechanical module, a stirring structure and a clamping structure, characterized in that an exhaust fan is installed at the right side wall of the industrial computer, an inlet fan is installed at the left side wall of the industrial computer, an observation window is arranged on the right side of the front end of the industrial computer, a controller is arranged on the left side of the front end of the industrial computer, two fixed bases are symmetrically arranged on the left and right sides of the bottom end of the industrial computer, a three-axis drive mechanical module is arranged on the upper end of the fixed base, the three-axis drive mechanical module is composed of three groups of drive modules, namely horizontal, front and back, and up and down, and the driving process is controlled by a controller driver program, a workbench is arranged inside the industrial computer and on the upper side of the horizontal drive module, and a stirring structure is arranged on the left side of the upper end of the workbench.

[0006] Preferably, the stirring structure includes a metal incubation seat, a placement seat, an incubation tank, a sample extraction tank, a motor, a transmission shaft, a baffle bracket, a filter membrane, a top cover and a liquid suction groove, a metal incubation seat is arranged on the left side of the upper end of the workbench, two placement seats are arranged at the bottom end of the metal incubation seat, a sample extraction tank is arranged inside the placement seat, and two incubation tanks are provided at the upper end of the metal incubation seat, a baffle bracket is arranged at the bottom end of the sample extraction tank, and a number of filter membranes are arranged inside the baffle bracket, a top cover is arranged at the upper end of the sample extraction tank, a motor is arranged on one side of the top end of the top cover, the output end of the motor is fixedly connected to the transmission shaft, and the transmission shaft is provided with a spiral blade, a liquid suction groove is provided on the upper end of the top cover away from the motor, and a clamping structure is provided on both left and right sides of the top cover;

[0007] Preferably, the clamping structure comprises a clamping groove, a round rod, a slide plate, a first spring, a clamping block, a cylinder, a rotating shaft, a linkage rod, a movable plate, a protruding block, a sliding rod, a pressing block, a second spring and a top block, the left and right side walls of the sample extraction tank are provided with clamping grooves, two round rods are provided at the left and right ends of the top cover, the round rods are slidably connected with a slide plate, a first spring is provided between the end of the slide plate away from the sample extraction tank and the side wall of the top cover, and a clamping block is provided at the end of the slide plate close to the sample extraction tank, and a cylinder is provided at the front end of the clamping block, a rotating shaft is provided on the left and right sides of the top cover, a linkage rod is provided at one end of the rotating shaft, a movable groove is provided inside the linkage rod, and the cylinder is placed inside the movable groove;

[0008] Preferably, a movable plate is provided at the other end of the rotating shaft, protruding blocks are provided on both the left and right sides of the lower end of the top cover, a sliding rod is slidably connected inside the protruding block, a pressing block is provided at the end of the sliding rod away from the sample extraction tank, a second spring is provided on the sliding rod and located between the protruding block and the pressing block, and a top block is provided at the end of the sliding rod close to the sample extraction tank;

[0009] Preferably, a first storage seat is provided at the rear side of the upper end of the workbench, a plurality of replacement heads are provided inside the first storage seat, a second storage seat is provided at the upper end of the workbench and on the right side of the metal incubation seat, a plurality of solid phase extraction tubes are provided inside the second storage seat;

[0010] Preferably, an automatic liquid pipette is installed on the three-axis driving mechanical module, a liquid pipette head is installed at the lower end of the automatic liquid pipette, an automatic liquid adder is arranged on the right side of the automatic liquid pipette, and a liquid adding head is arranged at the lower end of the automatic liquid adder;

[0011] Preferably, the number of the sample extraction tank 17 and the solid phase extraction tube 42 is set to twelve, which can meet the simultaneous processing of twelve samples;

[0012] Preferably, the sample extraction tank and the solid phase extraction tube are both made of plastic materials resistant to organic reagent corrosion such as PP polypropylene and PE polyethylene through mold injection molding, and the volume of the sample extraction tank is 100cm 3, the volume of the solid phase extraction tube is 6mL;

[0013] Preferably, a liquid concentrator is provided on the right side of the workbench, and a plurality of hot air needles are installed inside the liquid concentrator, and twelve hot air needles are provided, and the hot air needles are bent, so that when the hot air is blown to the extract in the collection tube, liquid splashing caused by airflow will not occur, thereby preventing cross contamination of samples;

[0014] The above technical solution of the present invention has the following beneficial technical effects:

[0015] The present invention uses multiple sample extraction tanks, solid phase extraction tubes, and liquid concentrators to work together to meet the requirements of processing twelve samples at the same time, preventing the problem of cross contamination of samples caused by using one liquid addition and washing liquid pipeline, and avoiding the problems of symmetrical placement of samples, long time, low efficiency, heavy equipment, and high noise during centrifugation, thereby effectively improving work efficiency;

[0016] The present invention presses the pressing block to squeeze and deform the second spring, and at the same time the sliding rod and the top block move toward the movable plate, the movable plate rotates during the pushing of the top block, and then drives the linkage rod to rotate, and with the help of the mutual cooperation between the cylinder and the linkage rod, drives the clamping block to move out of the clamping groove, so that the operator can directly remove the top cover from the sample extraction tank, and complete the fastening connection between the top cover and the sample extraction tank through the mutual cooperation between the clamping block and the clamping groove, so as to prevent the top cover from shaking when the transmission shaft stirs the sample and affects the stirring, thereby improving the processing efficiency;

[0017] The present invention performs ventilation treatment on the interior of the industrial computer through an exhaust fan and an inlet fan, and exhausts the waste gas generated inside to an external ventilation and purification device through the exhaust fan, thereby preventing the generation of toxic gases or odors. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic structural diagram of a cross-infection-proof sample pre-treatment instrument with coordinated operation of multiple holes proposed by the present invention.

[0019] Figure 2 This is a front view of a cross-infection-proof sample pre-treatment instrument with multiple holes in cooperation with each other proposed by the present invention.

[0020] Figure 3 The present invention provides a schematic structural diagram of a sample extraction tank in a cross-infection prevention sample pre-treatment instrument with coordinated operation of multiple holes.

[0021] Figure 4 For the present invention Figure 3 Schematic diagram of the enlarged structure of A.

[0022] Figure 5This is a schematic structural diagram of a liquid concentrator in a cross-infection-proof sample pre-treatment instrument with coordinated operation of multiple holes proposed by the present invention.

[0023] Figure numerals: 1, industrial computer; 2, exhaust fan; 3, air intake fan; 4, observation window; 5, controller; 6, fixed base; 7, three-axis drive mechanical module; 8, automatic liquid pipette; 9, liquid pipette head; 10, automatic liquid adder; 11, liquid adding head; 12, second storage seat; 13, workbench; 14, metal incubation seat; 15, placement seat; 16, incubation tank; 17, sample extraction tank; 18, motor; 19, transmission shaft; 20, partition bracket; 21 , filter membrane; 22, top cover; 23, liquid suction groove; 24, snap-in groove; 25, round rod; 26, slide plate; 27, first spring; 28, snap-in block; 29, cylinder; 30, rotating shaft; 31, linkage rod; 32, movable plate; 33, protruding block; 34, slide rod; 35, pressing block; 36, second spring; 37, top block; 38, first storage seat; 39, replacement head; 40, liquid concentrator; 41, hot air needle; 42, solid phase extraction tube. DETAILED DESCRIPTION

[0024] In order to make the purpose, technical scheme and advantages of the present invention clearer, the present invention is further described in detail below in conjunction with specific embodiments and with reference to the accompanying drawings. It should be understood that these descriptions are only exemplary and are not intended to limit the scope of the present invention. In addition, in the following description, the description of well-known structures and technologies is omitted to avoid unnecessary confusion of the concept of the present invention.

[0025] like Figure 1-5As shown, a cross-infection prevention sample pre-processing instrument for multi-hole cooperation operation proposed by the present invention includes an industrial computer 1, a three-axis drive mechanical module 7, a stirring structure and a clamping structure, characterized in that an exhaust fan 2 is installed at the right wall of the industrial computer 1, and an inlet fan 3 is installed at the left wall of the industrial computer 1. During the operation process, the exhaust fan 2 and the inlet fan 3 are used to ventilate the interior of the industrial computer 1, and the exhaust fan 2 is used to discharge the exhaust gas generated inside to an external ventilation and purification device to prevent the generation of toxic gases or odors. An observation window 4 is arranged on the right side of the front end of the industrial computer 1, and a controller 5 is arranged on the left side of the front end of the industrial computer 1. Two fixed bases 6 are symmetrically arranged on the left and right sides of the bottom end of the industrial computer 1, and a three-axis drive mechanical module 7 is arranged on the upper end of the fixed base 6. Group 7 consists of three groups of drive modules, namely horizontal, front and back, and up and down. An automatic pipette 8 is installed on the three-axis drive mechanical module 7. A pipette head 9 is installed at the lower end of the automatic pipette 8. An automatic liquid adder 10 is arranged on the right side of the automatic pipette 8. A liquid adding head 11 is arranged at the lower end of the automatic liquid adder 10. A workbench 13 is arranged inside the industrial computer 1 and located on the upper side of the horizontal drive module. A stirring structure is arranged on the left side of the upper end of the workbench 13. The running program is selected through the controller 5. The system moves the automatic liquid adder 8 to the top of the sample extraction tank 17 through the three-axis drive mechanical module 7 according to the project program pre-set by the controller 5, inserts the liquid adding head 11 of the automatic liquid adder 8 into the multi-porous disposable sample extraction tank 17, and injects the sample extract (acetonitrile) into the sample extraction tank 17 through the automatic liquid adder 8.

[0026] In an optional embodiment, the stirring structure includes a metal incubation seat 14, a placement seat 15, an incubation tank 16, a sample extraction tank 17, a motor 18, a transmission shaft 19, a baffle bracket 20, a filter membrane 21, a top cover 22 and a liquid suction tank 23. The metal incubation seat 14 is arranged on the left side of the upper end of the workbench 13, two placement seats 15 are arranged at the bottom end of the metal incubation seat 14, a sample extraction tank 17 is arranged inside the placement seat 15, and two incubation tanks 16 are opened at the upper end of the metal incubation seat 14, a baffle bracket 20 is arranged at the bottom end of the sample extraction tank 17, and a plurality of filter membranes 21 are arranged inside the baffle bracket 20. The material of the filter membrane 21 can be selected from but not limited to nylon, cellulose acetate, polypropylene mesh, glass fiber, polytetrafluoroethylene, nitrocellulose, polyamide, etc. A top cover 22 is provided at the upper end of the sample extraction tank 17, and a motor 18 is provided on one side of the top end inside the top cover 22. A transmission shaft 19 is fixedly connected to the output end of the motor 18, and a spiral blade is provided on the transmission shaft 19. A liquid suction groove 23 is provided on the upper end of the top cover 22 away from the motor 18, and a clamping structure is provided on both the left and right sides of the top cover 22. The transmission shaft 19 is driven by the motor 18 to stir, so that the liquid and solid in the porous disposable sample extraction tank 17 are fully stirred. Due to the action of gravity, the liquid will gradually penetrate the filter membrane 21 and flow to the liquid collection area. During the stirring process, the metal incubation seat 14 begins to heat up to 37 degrees Celsius. After stirring for a certain period of time, when the liquid level heights in the stirring interval and the liquid collection area reach a stable consistency, the extraction of the substance is fully achieved.

[0027] In an optional embodiment, the clamping structure includes a clamping groove 24, a round rod 25, a slide plate 26, a first spring 27, a clamping block 28, a cylinder 29, a rotating shaft 30, a linkage rod 31, a movable plate 32, a protruding block 33, a sliding rod 34, a pressing block 35, a second spring 36 and a top block 37. The left and right side walls of the sample extraction tank 17 are provided with a clamping groove 24, and two round rods 25 are provided at both left and right ends of the top cover 22. The slide plate 26 is slidably connected to the round rod 25. The first spring 27 is provided between the end of the slide plate 26 away from the sample extraction tank 17 and the side wall of the top cover 22, and the clamping block 28 is provided at the end of the slide plate 26 close to the sample extraction tank 17, and the front end of the clamping block 28 is provided with a cylinder 29, the left and right sides of the top cover 22 are provided with a rotating shaft 30, a linkage rod 31 is provided at one end of the rotating shaft 30, and a movable groove is provided inside the linkage rod 31, and the round rod 25 is provided with a movable groove. The column 29 is placed inside the movable groove, and a movable plate 32 is provided at the other end of the rotating shaft 30. A protruding block 33 is provided on the left and right sides of the lower end of the top cover 22. A sliding rod 34 is slidably connected inside the protruding block 33. A pressing block 35 is provided at the end of the sliding rod 34 away from the sample extraction tank 17. A second spring 36 is provided on the sliding rod 34 and between the protruding block 33 and the pressing block 35, and a top block 37 is provided at the end of the sliding rod 34 close to the sample extraction tank 17. By pressing the pressing block 35 inwardly, the second spring 36 is squeezed and deformed. At the same time, the sliding rod 34 and the top block 37 move toward the movable plate 32. The movable plate 32 rotates during the pushing of the top block 37, thereby driving the linkage rod 31 to rotate. With the help of the mutual cooperation of the cylinder 29 and the linkage rod 31, the clamping block 28 is driven to move out of the clamping groove 24, and the operator can directly remove the top cover 22 from the sample extraction tank 17.

[0028] In an optional embodiment, a first storage seat 38 is provided at the rear side of the upper end of the workbench 13, and a plurality of replacement heads 39 are provided inside the first storage seat 38. A second storage seat 12 is provided at the upper end of the workbench 13 and on the right side of the metal incubation seat 14, and a plurality of solid phase extraction tubes 42 are provided inside the second storage seat 12. The number of sample extraction tanks 17 and solid phase extraction tubes 42 is twelve, and the sample extraction tanks 17 and solid phase extraction tubes 42 are formed by mold injection molding of plastic materials resistant to corrosion by organic reagents such as PP polypropylene and PE polyethylene. The volume of the sample extraction tank 17 is 100 cm 3 , the volume of the solid phase extraction tube 42 is 6 mL.

[0029] The working principle of the present invention is as follows: when in use, first open the sample observation window 4, then put the sample to be processed into a plurality of pre-assembled disposable sample extraction tanks 17, the number of sample extraction tanks 17 is set to twelve, and twelve samples can be processed at the same time, then the sample extraction tank 17 is placed in the metal incubation seat 14, and then the controller 5 is used to select the running program, and the system moves the automatic liquid adder 8 to the top of the sample extraction tank 17 through the three-axis drive mechanical module 7 according to the project program pre-set by the controller 5, and the liquid adding head 11 of the automatic liquid adder 8 is inserted into the multi-porous disposable sample extraction tank 17, and the sample extraction liquid (acetonitrile) is injected into the sample extraction tank 17 through the automatic liquid adder 8, and the sample extraction liquid (acetonitrile) ) After the liquid addition is completed, the automatic liquid adder 8 is controlled to move out from the sample extraction tank 17, and then a plurality of top covers 22 are placed on the sample extraction tank 17. After placement, the motor 18 is started, and the transmission shaft 19 is driven by the motor 18 to stir, so that the liquid and solid in the porous disposable sample extraction tank 17 are fully stirred, and the liquid gradually penetrates the filter membrane 21 due to gravity and flows to the liquid collection area. During the stirring process, the metal incubation seat 14 begins to heat up to 37 degrees Celsius. After stirring for a certain period of time, when the liquid level in the stirring interval and the liquid collection area reaches a stable consistency, the extraction of the substance is sufficient, and then the pressing block 35 is pressed inwardly. At this time, the second spring 36 is squeezed and deformed, and at the same time, the slide bar 34 and the top block 37 move toward the movable plate 3 2, the movable plate 32 rotates during the pushing of the top block 37, thereby driving the linkage rod 31 to rotate, and with the help of the mutual cooperation between the cylinder 29 and the linkage rod 31, the clamping block 28 is driven to move out of the clamping groove 24, and the operator can directly remove the top cover 22 from the sample extraction tank 17, and complete the fastening connection between the top cover 22 and the sample extraction tank 17 through the mutual cooperation between the clamping block 28 and the clamping groove 24, so as to prevent the top cover 22 from shaking when the transmission shaft 19 stirs the sample and affects the stirring, thereby improving the processing efficiency, and then the metal incubation seat 14 begins to cool down to room temperature, and then the operator draws the activation liquid (distilled water) into the automatic liquid adding arm 21, and according to the project program pre-set by the controller 5, the automatic liquid adding arm 21 is driven by the three-axis drive The mechanical module 7 moves to the top of the solid phase extraction tube 42, and adds the activation liquid (distilled water) into the solid phase extraction tube 42 for activation treatment. The liquid will be automatically discharged to the waste liquid recovery box at the bottom of the multi-porous solid phase extraction tube 42. After the activation treatment is completed, the automatic liquid pipette 8 moves to the replacement head 39 to replace the liquid pipette head 9, and then absorbs the liquid in the liquid collection area of ​​the sample extraction tank 17, and adds the liquid into the solid phase extraction tube 42. The liquid will be automatically discharged to the waste liquid recovery box at the bottom of the solid phase extraction tube 42. After the activation process is completed, the liquid concentrator 40 moves to the bottom of the multi-porous solid phase extraction tube 42, and the automatic liquid adder 8 moves to the top of the solid phase extraction tube 42 to absorb the extraction liquid (ethyl acetate) and add it into the solid phase extraction tube 42 for extraction treatment.The extraction liquid will automatically flow into the tube of the liquid concentrator 40. During the extraction process, hot air (temperature controlled at 60°C) is blown out through the hot air needle 41 to concentrate the liquid in the tube of the liquid concentrator 40. The concentration process will continue until the liquid in the tube of the liquid concentrator 40 is completely evaporated. After it is completely evaporated, the controller 5 will emit a prompt sound to remind that the work has been completed. The operator takes out the concentration tube and the sample extraction tank 17 in the liquid concentrator 40 through the observation window 4. During the operation process, the exhaust fan 2 and the inlet fan 3 are used to ventilate the inside of the industrial computer 1. The exhaust fan 2 The waste gas generated inside is discharged to the external ventilation and purification device to prevent the generation of toxic gases or odors. The present invention cooperates with multiple sample extraction tanks 17, solid phase extraction tubes 42, and liquid concentrators 40 to meet the simultaneous processing of twelve samples, preventing the problem of cross contamination of samples caused by using one liquid addition and washing liquid pipeline, and avoiding the problems of symmetrical placement of samples, long time, low efficiency, heavy equipment, and high noise generated by centrifugation, effectively improving work efficiency and the extraction efficiency of samples, especially for the treatment of samples with odor and corruption.

[0030] It should be understood that the above specific embodiments of the present invention are used to illustrate or explain the principles of the present invention, and do not constitute a limitation of the present invention. Therefore, any modifications, equivalent substitutions, improvements, etc. made without departing from the spirit and scope of the present invention should be included in the protection scope of the present invention. In addition, the appended claims of the present invention are intended to cover all changes and modifications that fall within the scope and boundaries of the appended claims, or the equivalent forms of such scope and boundaries.

Claims

1. A cross-infection-proof sample pre-processing instrument with multi-hole coordinated operation, comprising an industrial computer (1), a three-axis drive mechanical module (7), a stirring structure and a clamping structure, characterized in that: An exhaust fan (2) is installed on the right side wall of the industrial computer (1), an intake fan (3) is installed on the left side wall of the industrial computer (1), an observation window (4) is arranged on the right side of the front end of the industrial computer (1), a controller (5) is arranged on the left side of the front end of the industrial computer (1), two fixed bases (6) are symmetrically arranged on the left and right sides of the bottom end of the industrial computer (1), a three-axis drive mechanical module (7) is arranged on the upper end of the fixed base (6), and the three-axis drive mechanical module (7) is composed of three groups of drive modules: horizontal, front and back, and upper and lower. A workbench (13) is arranged inside the industrial computer (1) and on the upper side of the horizontal drive module, and a stirring structure is arranged on the left side of the upper end of the workbench (13).

2. The cross-infection-proof sample pre-treatment instrument with multiple wells for coordinated operation according to claim 1, characterized in that: The stirring structure comprises a metal incubation seat (14), a placement seat (15), an incubation tank (16), a sample extraction tank (17), a motor (18), a transmission shaft (19), a barrier bracket (20), a filter membrane (21), a top cover (22) and a liquid suction tank (23); the metal incubation seat (14) is arranged on the left side of the upper end of the workbench (13); two placement seats (15) are arranged at the bottom end of the metal incubation seat (14); a sample extraction tank (17) is arranged inside the placement seat (15); and two incubation tanks (16) are provided at the upper end of the metal incubation seat (14). ), a barrier bracket (20) is arranged at the bottom of the sample extraction tank (17), and a plurality of filter membranes (21) are arranged inside the barrier bracket (20), a top cover (22) is arranged at the top end of the sample extraction tank (17), a motor (18) is arranged at one side of the top end of the top cover (22), the output end of the motor (18) is fixedly connected to a transmission shaft (19), and a spiral blade is arranged on the transmission shaft (19), a liquid suction groove (23) is arranged on the side of the top end of the top cover (22) away from the motor (18), and a clamping structure is arranged on both left and right sides of the top cover (22).

3. The cross-infection-proof sample pre-treatment instrument with multiple wells for coordinated operation according to claim 2, characterized in that: The clamping structure comprises a clamping groove (24), a round rod (25), a slide plate (26), a first spring (27), a clamping block (28), a cylinder (29), a rotating shaft (30), a linkage rod (31), a movable plate (32), a protruding block (33), a sliding rod (34), a pressing block (35), a second spring (36) and a top block (37). The left and right side walls of the sample extraction tank (17) are both provided with a clamping groove (24). Two round rods (25) are provided at both left and right ends of the top cover (22). The sliding connection on the round rods (25) A slide plate (26) is connected, a first spring (27) is arranged between the end of the slide plate (26) away from the sample extraction tank (17) and the side wall of the top cover (22), and a clamping block (28) is arranged at the end of the slide plate (26) close to the sample extraction tank (17), and a cylinder (29) is arranged at the front end of the clamping block (28), and a rotating shaft (30) is arranged on both left and right sides of the top cover (22), a linkage rod (31) is arranged at one end of the rotating shaft (30), and a movable groove is opened inside the linkage rod (31), and the cylinder (29) is placed inside the movable groove.

4. The cross-infection-proof sample pre-treatment instrument with multiple wells for coordinated operation according to claim 3, characterized in that: A movable plate (32) is arranged at the other end of the rotating shaft (30), and protruding blocks (33) are arranged on both left and right sides of the lower end of the top cover (22). A sliding rod (34) is slidably connected inside the protruding block (33), and a pressing block (35) is arranged at the end of the sliding rod (34) away from the sample extraction tank (17). A second spring (36) is arranged on the sliding rod (34) and located between the protruding block (33) and the pressing block (35), and a top block (37) is arranged at the end of the sliding rod (34) close to the sample extraction tank (17).

5. The cross-infection prevention sample pre-treatment instrument with multiple wells coordinated operation according to claim 1, characterized in that: A first storage seat (38) is arranged at the rear side of the upper end of the workbench (13), and a plurality of replacement heads (39) are arranged inside the first storage seat (38). A second storage seat (12) is arranged at the upper end of the workbench (13) and on the right side of the metal incubation seat (14), and a plurality of solid phase extraction tubes (42) are arranged inside the second storage seat (12).

6. The cross-infection prevention sample pre-treatment instrument with multiple wells coordinated operation according to claim 1, characterized in that: An automatic liquid aspirator (8) is installed on the three-axis driving mechanical module (7), a liquid aspirator head (9) is installed at the lower end of the automatic liquid aspirator (8), an automatic liquid adder (10) is arranged on the right side of the automatic liquid aspirator (8), and a liquid adding head (11) is arranged at the lower end of the automatic liquid adder (10).

7. The cross-infection prevention sample pre-treatment instrument with multiple wells coordinated operation according to claim 2, characterized in that: The number of the sample extraction tanks (17) and the number of the solid phase extraction tubes (42) are both twelve.

8. The cross-infection prevention sample pre-treatment instrument with multiple wells for coordinated operation according to claim 2, characterized in that: The sample extraction tank (17) and the solid phase extraction tube (42) are both made of plastic materials resistant to organic reagent corrosion, such as PP polypropylene, PE polyethylene, etc., through mold injection molding. The volume of the sample extraction tank (17) is 100 cm 3 The volume of the solid phase extraction tube (42) is 6 mL, and a waste liquid recovery box is provided on the right side of the bottom end of the industrial computer (1).

9. The cross-infection prevention sample pre-treatment instrument with multiple wells coordinated operation according to claim 1, characterized in that: A liquid concentrator (40) is arranged on the right side inside the workbench (13), and a plurality of hot air needles (41) are installed inside the liquid concentrator (40). Twelve hot air needles (41) are arranged, and the hot air needles (41) are bent.

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