Eye movement recording electrode and use method thereof

Abstract

The invention provides an eye movement recording electrode and a using method thereof. The eye movement recording electrode comprises a round skin electrode, a reference electrode, a round metal contact set evenly connected to the round skin electrode, a wire harness connected with the round skin electrode and the reference electrode and a signal collecting device connected with the wire harness. The circular metal contact group comprises electrodes Ch1 +, Ch2 +, Ch3 +, Ch4 +, Ch5 +, Ch6 +, Ch1-, Ch2-, Ch3-, Ch4-, Ch5-and Ch6-which are uniformly connected to the circular skin electrode in sequence and are mutually insulated. According to the eye movement recording electrode and the using method thereof, the eye movement recording electrode is more convenient, accurate, multi-directional and non-invasive, the annular electrode attached to the periphery of the eye socket is used for recording the electrophysiological signals of the eye movement, the up-down, left-right and oblique eye movement tracks can be recognized, whether the eyeball conducts twisting movement similar to the circumference or not can be judged, and the eye movement recording effect is improved. The method is expected to be used for clinical recording and analysis of eye movement.

Description

Technical Field

[0001] The present invention relates to the field of measurement technology, and in particular to an eye movement recording electrode and a use method thereof. Background Art

[0002] With the continuous expansion and application of new technologies in the medical field, the collection and recording of eye movement signals has gradually changed from skin electrophysiological signals ENG / EOG to video collection and recording VNG / VOG, which not only expands its application scope, but also further improves the diagnosis level of eye diseases through image playback and analysis. However, the use of video to collect eye movements cannot completely replace the role of skin electrodes in collecting eye movement signals. The circular ring skin electrode of the present invention highlights this feature.

[0003] The prerequisite for video eye movement recording and collection is that the patient must be in an open-eye state, but in some special cases, the patient is in a closed-eye state, such as during anesthesia, sleep, and the onset of special eye diseases. Eye movement analysis under such conditions, especially in different directions, is of great value to clinical treatment.

[0004] Therefore, a more convenient, accurate, multi-directional, and non-invasive eye movement recording method is needed. Summary of the invention

[0005] The present invention aims to provide an eye movement recording electrode and a method of using the same. The electrophysiological signals of eye movements are recorded by a ring electrode attached around the eye socket, and the trajectories of up and down, left and right, and oblique eye movements can be identified. It can also determine whether the eyeball is performing a nearly circular twisting motion, so as to be used for clinical recording and analysis of eye movements.

[0006] The present invention provides an eye movement recording electrode, comprising a circular skin electrode, a reference electrode, a circular metal contact group uniformly connected to the circular skin electrode, a wire bundle connected to the circular skin electrode and the reference electrode, and a signal acquisition device connected to the wire bundle;

[0007] The circular metal contact group includes electrodes Ch1+, Ch2+, Ch3+, Ch4+, Ch5+, Ch6+, Ch1-, Ch2-, Ch3-, Ch4-, Ch5- and Ch6- which are uniformly connected to the circular skin electrode in sequence and insulated from each other, the electrode Ch1+ is located at the top and the electrode Ch1- is located at the bottom, the electrodes Ch1+ and Ch1- record the amplitude and / or intensity of eye movements in the vertical direction, the electrodes Ch4+ and Ch4- record the amplitude and / or intensity of eye movements in the horizontal direction, the electrodes Ch2+ and Ch2-, the electrodes Ch3+ and Ch3-, the electrodes Ch5+ and Ch5-, the electrodes Ch6+ and Ch6- record the amplitude and / or intensity of oblique eye movements at different angles in groups;

[0008] The signal acquisition device includes six groups of signal acquisition circuits with the same structure. The signal acquisition circuit includes a first preamplifier, an optical isolator, a filter and a second preamplifier connected in sequence. The input end of the first preamplifier is connected to two electrodes and a reference electrode in opposite directions. The output end of the second preamplifier outputs a voltage V out ;

[0009] The electrophysiological signal generated by eye movement makes the output voltage V out Positive or negative increment.

[0010] In the eye movement recording electrode of the present invention, as a preferred embodiment, the first preamplifier and the second preamplifier are both differential amplifiers;

[0011]

[0012] in, is the voltage of electrode Ch1+, electrode Ch2+, electrode Ch3+, electrode Ch4+, electrode Ch5+, or electrode Ch6+, For Input voltage of electrodes in opposite positions, A d is the differential mode gain, A c is the common mode gain.

[0013] An eye movement recording electrode described in the present invention, as a preferred embodiment, the electrodes Ch1+, Ch2+, Ch3+, Ch4+, Ch5+, Ch6+, Ch1-, Ch2-, Ch3-, Ch4-, Ch5- and Ch6- are isolated by an insulating glue coating, 12 hollow electrode fixing rings are connected to the circular skin electrode, and the electrodes Ch1+, Ch2+, Ch3+, Ch4+, Ch5+, Ch6+, Ch1-, Ch2-, Ch3-, Ch4-, Ch5- and Ch6- are fixed inside the electrode fixing ring.

[0014] The eye movement recording electrode of the present invention is preferably a circular skin electrode with an inner diameter of 50 mm and an outer diameter of 65 mm.

[0015] The electrodes Ch1+, Ch2+, Ch3+, Ch4+, Ch5+, Ch6+, Ch1-, Ch2-, Ch3-, Ch4-, Ch5- and Ch6- are all circular metal contacts with a diameter of 5 mm.

[0016] In the eye movement recording electrode described in the present invention, as a preferred embodiment, the wire bundle is a 13-core wire bundle with a shielding layer.

[0017] The present invention provides a method for using an eye movement recording electrode, comprising the following steps:

[0018] S1. Stick the reference electrode on the forehead, stick the circular skin electrode on the eye socket and make the electrode Ch1+ located above the eye in the vertical direction, the electrode Ch1- located below the eye in the vertical direction, the electrode Ch4+ located on the right side of the eye in the horizontal direction, and the electrode Ch4- located on the left side of the eye in the horizontal direction, and connect the wire bundle to the signal acquisition device;

[0019] S2, start eye movement recording, and determine the movement mode of the eyeball according to the waveform output by the signal acquisition circuit;

[0020] When the signal acquisition circuit connected to electrodes Ch1+ and Ch1- outputs a waveform, the eyeball moves up and down;

[0021] When the signal acquisition circuit connected to electrodes Ch4+ and Ch4- outputs a waveform, the eyeball moves left and right;

[0022] When the signal acquisition circuit connected to electrodes Ch2+, Ch2-, Ch2+, Ch3-, Ch5+, Ch5-, Ch6+, Ch6- outputs a waveform whose amplitude is greater than that of electrodes Ch1+, Ch1-, Ch4+, Ch4-, the eyeball moves obliquely;

[0023] When the six signal acquisition circuits all output waveforms with amplitudes approximating the circular projection pattern, the eyeball makes a nearly circular twisting motion.

[0024] The method for using an eye movement recording electrode described in the present invention is, as a preferred embodiment, in step S2, when the signal acquisition circuit connected to electrodes Ch1+ and Ch1- outputs a positive increasing waveform, the signal of electrode Ch1+ is greater than the signal of electrode Ch1-, and the eyeball moves upward; when the signal acquisition circuit connected to electrodes Ch1+ and Ch1- outputs a negative increasing waveform, the eyeball moves downward.

[0025] The method for using the eye movement recording electrode of the present invention is, as a preferred mode, when the signal acquisition circuit connected to the electrodes Ch4+ and Ch4- outputs a positive increasing waveform, the signal of the electrode Ch4+ is greater than the signal of the electrode Ch4-, and the eyeball moves to the right; when the signal acquisition circuit connected to the electrodes Ch4+ and Ch4- outputs a negative increasing waveform, the eyeball moves to the left:

[0026] When the eyeball only moves up and down or left and right, the signal collection circuit connected to electrode Ch2+, electrode Ch2-, electrode Ch2+, electrode Ch3-, electrode Ch5+, electrode Ch5-, electrode Ch6+, electrode Ch6- has no signal output.

[0027] The method for using an eye movement recording electrode described in the present invention is, as a preferred embodiment, that when the eyeball moves obliquely or twists, the closer the eyeball is to electrode Ch1+ or electrode Ch1-, the closer the eyeball is to the vertical direction, and the amplitude of the signal acquisition circuit of electrode Ch1+ or electrode Ch1- gradually increases; the closer the eyeball is to electrode Ch4+ or electrode Ch4-, the closer the eyeball is to the horizontal direction, and the amplitude of the signal acquisition circuit of electrode Ch4+ or electrode Ch4- gradually increases.

[0028] The method for using an eye movement recording electrode described in the present invention is, as a preferred mode, that the eye movement recording electrode can detect eye movements in different directions when the patient has his eyes closed, and the output results of the eye movement recording electrode can be used to determine the depth of anesthesia.

[0029] The present invention has the following advantages:

[0030] The present invention provides a more convenient, accurate, multi-directional and non-invasive eye movement recording electrode and a method of using the same. The electrophysiological signals of eye movements are recorded by a ring electrode attached around the eye socket, and the trajectories of up and down, left and right, and oblique eye movements can be identified. It can also determine whether the eyeball is performing a nearly circular twisting motion, so as to be used for clinical recording and analysis of eye movements. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 This is a schematic diagram of the structure of an eye movement recording electrode;

[0032] Figure 2 A schematic diagram of a circular skin electrode structure for an eye movement recording electrode;

[0033] Figure 3 It is a circuit diagram of a signal acquisition device for eye movement recording electrodes;

[0034] Figure 4 A flow chart of a method for using an eye movement recording electrode;

[0035] Figure 5 A schematic diagram of the eye torsional movement waveform of an eye movement recording electrode.

[0036] Reference numerals:

[0037] 1. Circular skin electrode; 2. Reference electrode; 3. Circular metal contact group; 4. Wire bundle; 5. Signal acquisition device. DETAILED DESCRIPTION

[0038] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0039] Example 1

[0040] like Figures 1 to 4 As shown, an eye movement recording electrode and a method of using the same, the eye movement recording electrode includes an inner diameter 50mm, outer diameter It is a 65mm circular skin electrode 1, a reference electrode 2, a circular metal contact group 3 evenly distributed on the ring of the circular skin electrode 1, a wire bundle 4 connected to the circular skin electrode 1 and the reference electrode 2, and a signal acquisition device 5 connected to the wire bundle 4;

[0041] Round metal contact group 3 includes 6 pairs, 12 round metal contacts with a diameter of 5 mm: Ch1+ / Ch1-, Ch2+ / Ch2-, Ch3+ / Ch3-, Ch4+ / Ch4-, Ch5+ / Ch5-, Ch6+ / Ch6-, and must be used in strict accordance with Figure 1 , 2 The positions shown are attached to the eye sockets, that is, Ch1+ / Ch1- and Ch2+ / Ch2- must correspond to the vertical and horizontal directions respectively. These 6 pairs of electrodes represent:

[0042] Ch1+ / Ch1-: vertical eye movement amplitude (intensity);

[0043] Ch2+ / Ch2-: amplitude (intensity) of oblique eye movements;

[0044] Ch3+ / Ch3-: amplitude (intensity) of oblique eye movements;

[0045] Ch4+ / Ch4-: horizontal eye movement amplitude (intensity)

[0046] Ch5+ / Ch5-: amplitude (intensity) of oblique eye movements;

[0047] Ch6+ / Ch6-: amplitude (intensity) of oblique eye movements;

[0048] The 12 electrodes on the ring band are isolated by a biocompatible insulating adhesive coating, which also serves the function of attaching the ring electrode to the periphery of the eye socket; the inside of each electrode contact is coated with a concave anti-oxidation metal coating and attached with a conductive paste; the outside of the electrode is a raised metal surface (similar to a button electrode);

[0049] A 13-core wire harness 4 with a shielding layer brings together 12 (6 pairs) electrodes and a reference electrode 2 (at the forehead) and connects to a data acquisition device 4 composed of a multi-stage amplifier (see Figure 1 ).

[0050] The reference electrode 2 and any pair of electrodes form a differential input electrophysiological signal. The circuit principle is as follows Figure 3 shown.

[0051] The signal acquisition device 4 includes six groups of signal acquisition circuits with the same structure. The signal acquisition circuit includes a first preamplifier, an optical isolator, a filter and a second preamplifier connected in sequence. The input end of the first preamplifier is connected to two electrodes and a reference electrode in opposite directions. The output end of the second preamplifier outputs a voltage V out ;

[0052] A differential amplifier is an electronic amplifier that amplifies the difference between the voltages at its two input terminals. and Its output V out for:

[0053]

[0054] Among them, A d is the differential-mode gain, A c is the common-mode gain (Common-modeGain)

[0055] Since the differential amplifier unit has an inhibitory effect on common-mode signals, even if the temperature changes, the power supply voltage fluctuates, and there is external interference, the output of this type of common-mode signal is very small. c Tends to zero. For a completely symmetrical differential amplifier, its output voltage can be expressed as:

[0056]

[0057] In the present invention (reference Figure 3 ), the input signal in the above formula is Indicates Chn+, Indicates Chn-, where n = 1, 2, 3, 4, 5, 6 represent 6 pairs or 6 channels of recording electrodes respectively.

[0058] Normal people's eye movements are mainly horizontal, supplemented by vertical. Taking the vertical channel Ch1+ / Ch1- as an example, when the patient looks up Figure 3 The signal obtained at the output end shown in is positive, and the corresponding waveform on the computer display will move upward. In other words, at this time, the signal of Ch1+ at the input end is greater than the signal of Ch1-, and the output of the amplifier is positively increasing; conversely, when the patient looks down, the output of the amplifier is a negatively increasing signal, and the corresponding waveform on the computer display will move downward; similarly, taking the horizontal channel Ch4+ / Ch4- as an example, when the patient looks to the right, the signal obtained at the output end is positive, and the corresponding waveform on the computer display will move upward. At this time, the signal of Ch4+ at the input end is greater than the signal of Ch4- ( Figure 3The output of the amplifier is a positive increasing signal; conversely, when the patient looks to the left, the output of the amplifier is a negative increasing signal, and the corresponding waveform on the computer monitor will move downward; it should be noted that in the above state, except for the horizontal and vertical channels, other oblique channels will not have signal output.

[0059] When recording patients with eye diseases, oblique or torsional eye movements will occur. At this time, the waveform amplitude of the oblique channel is the largest, and the amplitudes in the horizontal and vertical directions are smaller than the amplitudes of the oblique channel. The closer to the vertical channel, the larger the amplitude of the channel; similarly, the closer to the horizontal channel, the larger the amplitude of the channel. The specific expression can be obtained by analyzing the time domain or frequency domain after processing the data.

[0060] After 4 oblique channels (ch2, ch3, ch5 and ch6), it is easy to identify the track of oblique eye movement; when all 6 channels have tracks ( Figure 5 ), and the amplitude is close to the circular projection law, it can be determined that the eyeball is making a nearly circular torsional motion.

[0061] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. An eye movement recording electrode, characterized in that: It comprises a circular skin electrode (1), a reference electrode (2), a circular metal contact group (3) uniformly connected to the circular skin electrode (1), a wire bundle (4) connected to the circular skin electrode (1) and the reference electrode (2), and a signal acquisition device (5) connected to the wire bundle (4); The circular metal contact group (3) comprises electrodes Ch1+, Ch2+, Ch3+, Ch4+, Ch5+, Ch6+, Ch1-, Ch2-, Ch3-, Ch4-, Ch5- and Ch6- which are uniformly connected to the circular skin electrode (1) in sequence and insulated from each other, the electrode Ch1+ is located at the top and the electrode Ch1- is located at the bottom, the electrodes Ch1+ and Ch1- record the amplitude and / or intensity of eye movements in the vertical direction, the electrodes Ch4+ and Ch4- record the amplitude and / or intensity of eye movements in the horizontal direction, the electrodes Ch2+ and Ch2-, the electrodes Ch3+ and Ch3-, the electrodes Ch5+ and Ch5-, the electrodes Ch6+ and Ch6- record the amplitude and / or intensity of oblique eye movements at different angles in groups; The signal acquisition device (5) comprises six groups of signal acquisition circuits with the same structure, wherein the signal acquisition circuits comprise a first preamplifier, an optical isolator, a filter and a second preamplifier connected in sequence, wherein the input end of the first preamplifier is connected to two electrodes in opposite directions and the reference electrode (2), and the output end of the second preamplifier outputs a voltage V out ; The electrophysiological signal generated by eye movement makes the output voltage V out Positive or negative increment.

2. An eye movement recording electrode according to claim 1, characterized in that: The first preamplifier and the second preamplifier are both differential amplifiers; in, is the voltage of electrode Ch1+, electrode Ch2+, electrode Ch3+, electrode Ch4+, electrode Ch5+, or electrode Ch6+, For Input voltage of electrodes in opposite positions, A d is the differential mode gain, A c is the common mode gain.

3. An eye movement recording electrode according to claim 1, characterized in that: The electrodes Ch1+, Ch2+, Ch3+, Ch4+, Ch5+, Ch6+, Ch1-, Ch2-, Ch3-, Ch4-, Ch5- and Ch6- are isolated by insulating glue coating, and 12 hollow electrode fixing rings are connected to the circular skin electrode (1), and the electrodes Ch1+, Ch2+, Ch3+, Ch4+, Ch5+, Ch6+, Ch1-, Ch2-, Ch3-, Ch4-, Ch5- and Ch6- are fixed inside the electrode fixing rings.

4. The eye movement recording electrode according to claim 1, characterized in that: The inner diameter of the circular skin electrode (1) is 50 mm and the outer diameter is 65 mm; The electrodes Ch1+, Ch2+, Ch3+, Ch4+, Ch5+, Ch6+, Ch1-, Ch2-, Ch3-, Ch4-, Ch5- and Ch6- are all circular metal contacts with a diameter of 5 mm.

5. The eye movement recording electrode according to claim 1, characterized in that: The wire bundle (4) is a 13-core wire bundle with a shielding layer.

6. A method for using an eye movement recording electrode according to any one of claims 1 to 5, characterized in that: The following steps are involved: S1, attaching the reference electrode (2) to the forehead, attaching the circular skin electrode (1) to the eye socket and making the electrode Ch1+ located above the eye in the vertical direction, the electrode Ch1- located below the eye in the vertical direction, the electrode Ch4+ located on the right side of the eye in the horizontal direction, and the electrode Ch4- located on the left side of the eye in the horizontal direction, and connecting the wire bundle (4) to the signal acquisition device (5); S2, start eye movement recording, and determine the movement mode of the eyeball according to the waveform output by the signal acquisition circuit; When the signal acquisition circuit connected to electrodes Ch1+ and Ch1- outputs a waveform, the eyeball moves up and down; When the signal acquisition circuit connected to electrodes Ch4+ and Ch4- outputs a waveform, the eyeball moves left and right; When the signal acquisition circuit connected to electrodes Ch2+, Ch2-, Ch2+, Ch3-, Ch5+, Ch5-, Ch6+, Ch6- outputs a waveform whose amplitude is greater than that of electrodes Ch1+, Ch1-, Ch4+, Ch4-, the eyeball moves obliquely; When the six signal acquisition circuits all output waveforms with amplitudes approximating the circular projection pattern, the eyeball makes a nearly circular twisting motion.

7. The method for using the eye movement recording electrode according to claim 6, characterized in that: In step S2, when the signal acquisition circuit connected to electrodes Ch1+ and Ch1- outputs a positive increasing waveform, the signal of electrode Ch1+ is greater than the signal of electrode Ch1-, and the eyeball moves upward; when the signal acquisition circuit connected to electrodes Ch1+ and Ch1- outputs a negative increasing waveform, the eyeball moves downward.

8. The method for using an eye movement recording electrode according to claim 6, characterized in that: When the signal acquisition circuit connected to electrodes Ch4+ and Ch4- outputs a positive increasing waveform, the signal of electrode Ch4+ is greater than the signal of electrode Ch4-, and the eyeball moves to the right; when the signal acquisition circuit connected to electrodes Ch4+ and Ch4- outputs a negative increasing waveform, the eyeball moves to the left: When the eyeball only moves up and down or left and right, the signal collection circuit connected to electrode Ch2+, electrode Ch2-, electrode Ch2+, electrode Ch3-, electrode Ch5+, electrode Ch5-, electrode Ch6+, electrode Ch6- has no signal output.

9. The method for using an eye movement recording electrode according to claim 6, characterized in that: When the eyeball moves obliquely or twists, the closer the eyeball is to electrode Ch1+ or electrode Ch1-, the closer the eyeball is to the vertical direction, and the amplitude of the signal acquisition circuit of electrode Ch1+ or electrode Ch1- gradually increases; the closer the eyeball is to electrode Ch4+ or electrode Ch4-, the closer the eyeball is to the horizontal direction, and the amplitude of the signal acquisition circuit of electrode Ch4+ or electrode Ch4- gradually increases.

10. The method for using an eye movement recording electrode according to claim 1, characterized in that: The eye movement recording electrodes can detect eye movements in different directions when the patient has his eyes closed, and the output results of the eye movement recording electrodes can be used to determine the depth of anesthesia.

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