A high-content, all-natural oil-based cream without emulsifiers and its preparation method

Abstract

This invention discloses a high-content, all-naturally derived oil-based cream without emulsifiers and its preparation method, belonging to the field of cosmetic technology. By mass percentage, the raw materials for preparing this cream include 30%–40% emollient, 5%–10% moisturizer, 0.5%–5% thickener, 0.01%–0.2% chelating agent, 0.01%–0.5% pH adjuster, and 0.6%–1% preservative, with the balance being water. The emollient is an all-naturally derived oil; the mass ratio of the acrylate / C10-30 alkanol acrylate crosspolymer in the thickener to the pH adjuster is 1:0.9 to 1:1.1. This cream is characterized by being emulsifier-free, low in preservatives, and high in oil content. Furthermore, it is mild and non-irritating, possessing good stability and antibacterial effects, meeting the requirements of cosmetics. Its preparation method is simple, easy to operate, and suitable for industrial production.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, and more specifically, to a high-content, all-natural oil-based cream without emulsifiers and its preparation method. Background Technology

[0002] Emulsifiers are ingredients used to stabilize oils, especially in cosmetics with high oil content. They enhance stability and prevent issues like layering, oil separation, and emulsion breaking. However, high-oil-content cosmetics often require emulsifiers with strong emulsifying abilities or higher dosages to achieve good stability. Conversely, strong emulsifying abilities or high dosages can irritate the skin, especially sensitive skin. For example, while polyether emulsifiers often have strong emulsifying properties, the production process inevitably introduces potentially hazardous components like dioxane, which can affect the product's mildness.

[0003] Preservatives are the second leading cause of cosmetic allergies and contact dermatitis, after fragrances. In cosmetics, preservatives inhibit the growth of microorganisms. Currently, influenced by market developments, more and more products are required to be "preservative-free" (or "alternative preservatives," hereinafter referred to as "preservative-free" for consistency). "Preservative-free" is not a legally mandated requirement, but rather a market-driven term, typically referring to products that do not contain the 51 permitted preservatives listed in the "Cosmetic Safety Technical Specifications (2015 Edition)."

[0004] Currently, there are no creams or ointments that combine good stability and antibacterial effects while being high in oil content, free of emulsifiers, and low in preservatives.

[0005] In view of this, the present invention is proposed. Summary of the Invention

[0006] The purpose of this invention is to provide an emulsifier-free, high-content, all-naturally sourced oil cream and its preparation method, in order to solve or improve the above-mentioned technical problems.

[0007] This invention can be implemented as follows:

[0008] In a first aspect, the present invention provides a high-content, all-naturally derived oil-based cream without emulsifiers. By mass percentage, the raw materials for preparing the high-content, all-naturally derived oil-based cream include 30%–40% emollients, 5%–10% moisturizers, 0.5%–5% thickeners, 0.01%–0.2% chelating agents, 0.01%–0.5% pH adjusters, and 0.6%–1% preservatives, with the balance being water.

[0009] Moisturizers are oils of pure natural origin;

[0010] The thickener includes an acrylate / C10-30 alkanol acrylate crosspolymer, wherein the mass ratio of the acrylate / C10-30 alkanol acrylate crosspolymer in the thickener to the pH adjuster is 1:0.9 to 1:1.1.

[0011] In an optional embodiment, the raw materials for preparing high-content pure natural oil creams include, by mass percentage, 32%–38% emollients, 6%–8% humectants, 2%–3% thickeners, 0.01%–0.1% chelating agents, 0.2%–0.4% pH adjusters, and 0.6%–0.8% preservatives, with the balance being water.

[0012] In an optional embodiment, the raw materials for preparing a high-content, all-naturally sourced oil-based cream, by weight percentage, include 35% emollient, 7.1% humectant, 2.3% thickener, 0.05% chelating agent, 0.3% pH adjuster, and 0.6% preservative, with the balance being water.

[0013] In an optional embodiment, the emollient includes at least one of squalane, cocoyl alcohol-caprylate / caprylate, jojoba seed oil, and meadowfoam seed oil.

[0014] In an optional embodiment, the moisturizer includes at least one of glycerin, 1,3-butanediol, hyaluronic acid, and hydrogenated lecithin.

[0015] In an optional embodiment, the thickener also includes at least one of carbomer and cetearyl alcohol.

[0016] In an optional embodiment, the chelating agent includes EDTA-2Na.

[0017] In an optional embodiment, the pH adjuster includes at least one of sodium hydroxide, aminomethylpropanol, and arginine.

[0018] In an optional embodiment, the preservative includes at least one of p-hydroxyacetophenone and 1,2-hexanediol.

[0019] Secondly, the present invention provides a method for preparing a high-content pure natural source oil cream as described in any of the foregoing embodiments, comprising the following steps: mixing water, moisturizer and chelating agent in proportion and heating to obtain a first mixture; mixing emollient and thickener and heating to obtain a second mixture; mixing the first mixture and the second mixture to obtain a third mixture; adding a pH adjuster and then a preservative to the third mixture.

[0020] The beneficial effects of this invention include:

[0021] The cream provided by this invention is characterized by being free of emulsifiers, having a low preservative content (the amount of preservatives used can be reduced by about 40% compared with existing conventional cosmetics), and a high oil content (the amount of oil used is increased from 5% to 25% to 30% to 40% compared with existing conventional cosmetics). In addition, the cream is mild and non-irritating, and has good stability and antibacterial effect, which can meet the requirements of cosmetics. Detailed Implementation

[0022] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. Where specific conditions are not specified in the embodiments, conventional conditions or conditions recommended by the manufacturer shall apply. Reagents or instruments whose manufacturers are not specified are all conventional products that can be purchased commercially.

[0023] The following is a detailed description of the emulsifier-free, high-content, all-natural-source oil cream and its preparation method provided by the present invention.

[0024] This invention provides a high-content, all-naturally derived oil-based cream without emulsifiers. By mass percentage, the raw materials for preparing this high-content, all-naturally derived oil-based cream include 30%–40% emollient, 5%–10% moisturizer, 0.5%–5% thickener, 0.01%–0.2% chelating agent, 0.01%–0.5% pH adjuster, and 0.6%–1% preservative, with the balance being water.

[0025] Emollients can moisturize and hydrate the skin. Currently, the most commonly used oils in cosmetics are mineral oils and synthetic oils. These types of oils are relatively inexpensive, but they can affect the gentleness of the product. For example, mineral oils are petroleum-based, and the impurities they contain may have adverse effects on the skin; byproducts in synthetic oils often cause irritation.

[0026] The emollients used in this invention are naturally derived oils, which may include, but are not limited to, at least one of squalane, coconut oil-caprylate / caprylate, jojoba seed oil, and meadowfoam seed oil. By using these naturally derived oils, good skin affinity and gentleness can be achieved.

[0027] Squalane, derived from olives, can strengthen the repair of the epidermis, effectively form a natural protective film, help balance the skin and sebum, and has strong affinity, enabling it to integrate with the human body's own sebum film and form a natural barrier on the skin surface.

[0028] Cocoyl alcohol-caprylate / caprylate is a 100% natural plant-derived oil derived from the coconut plant, which can improve skin softness.

[0029] Jojoba seed oil is a natural, green plant-based oil obtained from the seeds of the desert shrub (jojoba) and can be used to protect and moisturize the skin.

[0030] Meadowfoam seed oil is 100% derived from the natural plant meadowfoam. It has excellent moisturizing properties and can improve the skin's barrier function.

[0031] In some alternative embodiments, the amount of emollient can be 30%, 31%, 32%, 33%, 34%, 35%, 36%, 37%, 38%, 39%, or 40%, or other values ​​within the range of 30% to 40%.

[0032] It should be noted that the maximum amount of oil in commonly used creams and ointments is currently around 25%. This is because a higher oil content necessitates the use of very high amounts of emulsifiers for stabilization, which could increase the skin's irritation and burden the skin. This invention breaks with conventional methods. By combining the use of other raw materials described in this application, it achieves a level of oil content of 30%–40% while ensuring the product remains essentially non-irritating to the skin.

[0033] In some alternative embodiments, the amount of humectant can be 5%, 5.5%, 6%, 6.5%, 7%, 7.5%, 8%, 8.5%, 9%, 9.5%, or 10%, or other values ​​within the range of 5% to 10%.

[0034] Moisturizers may include, but are not limited to, at least one of glycerin, 1,3-butanediol, hyaluronic acid, and hydrogenated lecithin.

[0035] In some alternative embodiments, the amount of thickener can be 0.5%, 1%, 1.5%, 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, or 5%, or other values ​​within the range of 0.5% to 5%.

[0036] The thickener includes acrylate / C10-30 alkanol acrylate crosspolymers, and may also include at least one of carbomer and cetearyl alcohol.

[0037] In some alternative embodiments, the amount of chelating agent may be 0.01%, 0.02%, 0.04%, 0.06%, 0.08%, 0.1%, 0.12%, 0.14%, 0.16%, 0.18%, or 0.2%, or other values ​​within the range of 0.01% to 0.2%.

[0038] Chelating agents may include, but are not limited to, EDTA-2Na.

[0039] In some alternative embodiments, the amount of pH adjuster may be 0.01%, 0.05%, 0.1%, 0.15%, 0.2%, 0.25%, 0.3%, 0.35%, 0.4%, 0.45%, or 0.5%, or other values ​​within the range of 0.01% to 0.5%.

[0040] pH adjusters may, by example but not in a limited manner, include at least one of sodium hydroxide, aminomethylpropanol, and arginine.

[0041] In some alternative implementations, the amount of preservative used can be 1%, 0.9%, 0.8%, 0.7%, or 0.6%, etc.

[0042] Preservatives may include, by way of example but not by way of limitation, at least one of p-hydroxyacetophenone and 1,2-hexanediol.

[0043] 1,2-Hexanediol is a polyol, colorless and transparent in appearance, and has good bactericidal and moisturizing effects. p-Hydroxyacetophenone is a natural component extracted from plants such as Artemisia capillaris; it has good water solubility and good antioxidant and antibacterial properties.

[0044] In some preferred embodiments, the raw materials for preparing high-content natural oil-based creams include, by mass percentage, 32%–38% emollients, 6%–8% humectants, 2%–3% thickeners, 0.01%–0.1% chelating agents, 0.2%–0.4% pH adjusters, and 0.6%–0.8% preservatives, with the balance being water.

[0045] In some typical embodiments, the mass ratio of the acrylate / C10-30 alkanol acrylate crosspolymer in the thickener to the pH adjuster is from 1:0.9 to 1:1.1, preferably 1:1.

[0046] In some preferred embodiments, the raw materials for preparing high-content, naturally derived oil-based creams, by weight percentage, include 35% emollient (composed of 10% squalane, 10% cocoyl oleate / caprylate, 10% jojoba seed oil, and 5% meadowfoam seed oil), 7.1% moisturizer (composed of 6% glycerin, 0.1% hyaluronic acid, and 1% hydrogenated lecithin), 2.3% thickener (composed of 0.3% acrylate / C10-30 alkanol acrylate crosspolymer and 2% cetearyl alcohol), 0.05% chelating agent (EDTA-2Na), 0.3% pH adjuster (arginine), and 0.6% preservative (composed of 0.3% 1,2-hexanediol and 0.3% p-hydroxyacetophenone), with the balance being water. The creams obtained under these superior conditions exhibit better stability and antibacterial properties, and are gentle and non-irritating.

[0047] It should be noted that the most common preservative system currently used is a combination of 1,2-hexanediol and hydroxyacetophenone, typically added at 0.5% and 0.5% respectively, to achieve a preservative effect that meets cosmetic requirements. This invention, by combining other raw materials, creatively reduces the amount of preservative used (e.g., to 0.6%, a 40% reduction compared to the existing mainstream combination of 0.5% 1,2-hexanediol and 0.5% p-hydroxyacetophenone) while still ensuring that the product meets cosmetic preservative requirements.

[0048] The reasons include:

[0049] ① Factors affecting the effectiveness of preservatives include not only the amount of preservative added, but also other factors such as pH value, water activity, preservative activity, and oil-water distribution ratio. In this invention, the main focus is on improving the preservative efficacy by increasing water activity and oil-water distribution ratio, so that a good preservative effect can still be achieved even when the amount of preservative added is reduced or not added.

[0050] Specifically, regarding water activity: not all water can be used for microbial growth; only free water is an indispensable component for microbial growth and metabolism. The lower the water activity, the less conducive it is to microbial growth. In the formulation of this invention, the high content of oil phase reduces water activity and improves the preservative effect, which explains why there is still a certain preservative effect when no preservative is added.

[0051] Regarding the oil-water distribution ratio: In face cream-type cosmetics, both oil and water phases exist simultaneously. The presence of preservatives in the water layer or at the interface directly affects the product's preservative ability. For the same dosage of preservative, a higher distribution ratio in the water results in a better preservative effect. In this invention, on the one hand, the oil content is very high, meaning the water content is low; on the other hand, the selected preservative is water-soluble, resulting in a higher concentration of the preservative in the water layer. This enhances the preservative efficacy and explains why a good preservative effect is still achieved even with a reduced dosage of preservative.

[0052] ② Conventional creams and ointments require the addition of emulsifiers to stabilize the oil phase in the formula. However, the thickener used in this invention, in addition to providing thickening properties, also possesses very low surface activity, stabilizing the oil-in-water system and exhibiting strong suspending power, further ensuring the stability of the formula system.

[0053] ③ This invention increases the amount of oil used without using a high amount of emulsifier, thus avoiding the adverse effects of high-volume emulsifiers. Furthermore, the oil used is of pure natural origin, ensuring high safety and gentleness, and avoiding the skin burden associated with mineral oils and synthetic oils even at high dosages.

[0054] As mentioned above, this cream is characterized by being free of emulsifiers, having a low preservative content (which can be reduced by about 40%), and a high oil content (increased from 5% to 25% to 30% to 40%). In addition, this cream is gentle and non-irritating, and has good stability and antibacterial effects, which can meet the requirements of cosmetics.

[0055] Accordingly, the present invention also provides a method for preparing the above-mentioned high-content pure natural oil cream without emulsifier, comprising the following steps: mixing water, moisturizer and chelating agent according to the ratio and heating to obtain a first mixture; mixing emollient and thickener and heating to obtain a second mixture; mixing the first mixture and the second mixture to obtain a third mixture; adding a pH adjuster and then adding a preservative to the third mixture.

[0056] Specifically, water, humectant, and chelating agent are added to an aqueous phase reactor according to the specified ratio and heated to 75℃~85℃ (e.g., 75℃, 78℃, 80℃, 82℃, or 85℃) to obtain a first mixture (aqueous phase); emollient and thickener are added to an oil phase reactor and heated to 75℃~85℃ (e.g., 75℃, 78℃, 80℃, 82℃, or 85℃) to obtain a second mixture (oil phase); the first and second mixtures are then processed in an emulsifying reactor at 3000r / min~5000r / min. Homogenize at a rotation speed of 1 min for 3 min to 10 min (e.g., 3 min, 5 min, 8 min, or 10 min) to obtain a third mixture; add a pH adjuster to the third mixture and stir to homogenize, turn on the cooling, and stir to cool down to 45℃ to 55℃ (e.g., 45℃, 48℃, 50℃, 52℃, or 55℃); then add a preservative, stir to homogenize, and stir to cool down to 36℃ to 40℃ (e.g., 36℃, 37℃, 38℃, 39℃, or 40℃); stop stirring and discharge the material.

[0057] As mentioned above, the preparation method of the emulsifier-free, high-content, all-natural-source oil cream provided by this invention is simple, easy to operate, and can be industrialized.

[0058] The features and performance of the present invention will be further described in detail below with reference to embodiments.

[0059] The following examples and comparative examples all provide a cream, and some of the raw materials used are from the following sources:

[0060] Squalane: Leybold Chemicals (Shanghai) Co., Ltd., trade name: OLIVE SQUALANE.

[0061] Cocoyl alcohol-caprylate / decanoate: BASF, trade name: C 5C.

[0062] Jojoba seed oil: Jojoba Company Inc., trade name: INCA JOJOBALITE.

[0063] Meadowfoam Seed Oil: Natural Plant Product, Trade Name: Meadowfoam Seed Oil XPR.

[0064] 1,2-Hexanediol: Osaka Organic Chemicals, Japan, trade name: KMO-6.

[0065] p-Hydroxyacetophenone: Symrise Fragrance & Flavor (Nantong) Co., Ltd., trade name: SYMSAVE H.

[0066] The features and performance of the present invention will be further described in detail below with reference to embodiments.

[0067] Examples 1-3 and Comparative Examples 1-14:

[0068] The composition of the formulations of Examples 1-3 and Comparative Examples 1-11 are shown in Tables 1 to 3.

[0069] The difference between Comparative Example 12 and Example 3 is that the oil used is mineral oil (specifically purchased from Zhejiang Zhengxin Petroleum Technology Co., Ltd., name: No. 26 cosmetic grade white oil).

[0070] The difference between Comparative Example 13 and Example 3 is that the oil used is a synthetic oil (specifically purchased from Dow (Zhangjiagang) Investment Co., Ltd., name: XIAMETER). TM PMX-200Silicone Fluid 350cSt).

[0071] The difference between Comparative Example 14 and Example 3 is that the preservative consists of 0.3% 1,2-pentanediol and 0.3% p-hydroxyacetophenone.

[0072] The creams provided in Examples 1-3 and Comparative Examples 1-14 were prepared according to the following method: water, moisturizer, and chelating agent were added to an aqueous phase pot according to the specified ratio and heated to 80°C to obtain a first mixture (aqueous phase); emollient and thickener were added to an oil phase pot and heated to 80°C to obtain a second mixture (oil phase); the first and second mixtures were homogenized in an emulsifying pot at a speed of 4000 r / min for 5 min to obtain a third mixture; a pH adjuster was added to the third mixture and stirred and homogenized, cooling was turned on, and the temperature was lowered to 50°C by stirring; then a preservative was added, and the mixture was stirred and homogenized, and the temperature was lowered to 38°C by stirring; stirring was stopped and the mixture was discharged.

[0073] The difference between Comparative Example 15 and Example 3 is that the third mixture was mixed simultaneously with the pH adjuster and the preservative.

[0074] Table 1. Composition of Examples 1-3

[0075]

[0076] Table 2. Composition of Comparative Examples 1-6

[0077]

[0078]

[0079] Table 3. Composition table of comparative examples 7-11

[0080]

[0081] Test Example 1

[0082] Stability test

[0083] The creams prepared in Examples 1-3 and Comparative Examples 1-15 were subjected to stability tests.

[0084] The experimental methods and conditions are based on the relevant content in QB / T 1857 Moisturizing Creams.

[0085] The experimental results are shown in Tables 4 to 7.

[0086] Table 4 Stability Test Items

[0087]

[0088] Table 5 Stability Test Items

[0089]

[0090] Table 6 Stability Test Items

[0091]

[0092] Table 7 Stability Test Items

[0093]

[0094]

[0095] As can be seen from Tables 4 to 7, the creams provided in Examples 1 to 3 of the present invention have good stability.

[0096] Test Example 2

[0097] Corrosion resistance test

[0098] The creams prepared in Examples 1-3 and Comparative Examples 1-15 were subjected to anti-corrosion tests, and the creams prepared in Examples 1-3 and Comparative Examples 1, 6, 7 and 14 were subjected to stability tests.

[0099] The testing methods and judgment criteria were all in accordance with (T / GDCDC010-2019 Challenge Test Method for Cosmetic Preservatives). Initial microbial content determination and preservation tests were performed according to the above methods, with two rounds of testing conducted and results observed at 3, 7, 14, 21, and 28 days.

[0100] The specific details of the microorganisms used in the preservation test are shown in Table 8. All bacteria and fungi were provided by the American Type Culture Collection (ATCC).

[0101] The inoculation amounts in the table below refer to the total inoculation amount of bacteria or fungi. The inoculation ratio of Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Burkholderia cepacia is 1:1:1:1, and the inoculation ratio of Candida albicans and Aspergillus brasiliensis is 1:1.

[0102] Table 8 Microorganisms used in corrosion resistance testing

[0103]

[0104] The experimental results are shown in Tables 9 and 10.

[0105] Table 9. Results of the anti-corrosion test (bacteria)

[0106] Inoculation volume, Day 0 Day 3 Day 7 Day 14 Day 21 Day 28 Example 1 <![CDATA[4.2×10 6 ]]> ＜10 ＜10 ＜10 ＜10 ＜10 Example 2 <![CDATA[4.2×10 6 ]]> ＜10 ＜10 ＜10 ＜10 ＜10 Example 3 <![CDATA[4.2×10 6 ]]> <![CDATA[1.5×10 2 ]]> ＜10 ＜10 ＜10 ＜10 Comparative Example 1 <![CDATA[4.4×10 6 ]]> <![CDATA[>3.0×10 5 ]]> <![CDATA[5.5×10 4 ]]> <![CDATA[4.4×10 3 ]]> <![CDATA[3.2×10 2 ]]> <![CDATA[2.0×10 1 ]]> Comparative Example 6 <![CDATA[3.6×10 6 ]]> ＜10 ＜10 ＜10 ＜10 ＜10 Comparative Example 9 <![CDATA[4.4×10 6 ]]> <![CDATA[2.5×10 2 ]]> <![CDATA[5.0×10 1 ]]> ＜10 ＜10 ＜10 Comparative Example 14 <![CDATA[4.2×10 6 ]]> <![CDATA[7.5×10 4 ]]> <![CDATA[3.2×10 3 ]]> <![CDATA[2.0×10 2 ]]> ＜10 ＜10

[0107] Table 10 Results of Anti-corrosion Tests (Fungi)

[0108] Inoculation volume, Day 0 Day 3 Day 7 Day 14 Day 21 Day 28 Example 1 <![CDATA[1.0×10 5 ]]> <![CDATA[1.0×10 1 ]]> ＜10 ＜10 ＜10 ＜10 Example 2 <![CDATA[1.0×10 5 ]]> <![CDATA[2.0×10 2 ]]> <![CDATA[3.0×10 1 ]]> ＜10 ＜10 ＜10 Example 3 <![CDATA[1.0×10 5 ]]> <![CDATA[3.0×10 2 ]]> <![CDATA[7.0×10 1 ]]> ＜10 ＜10 ＜10 Comparative Example 1 <![CDATA[1.0×10 5 ]]> <![CDATA[2.1×10 4 ]]> <![CDATA[7.0×10 3 ]]> <![CDATA[1.9×10 2 ]]> ＜10 ＜10 Comparative Example 6 <![CDATA[8.5×10 4 ]]> <![CDATA[3.9×10 4 ]]> <![CDATA[4.3×10 3 ]]> <![CDATA[2.1×10 2 ]]> <![CDATA[2.0×10 1 ]]> ＜10 Comparative Example 7 <![CDATA[1.0×10 5 ]]> <![CDATA[3.0×10 4 ]]> <![CDATA[3.5×10 3 ]]> <![CDATA[1.5×10 2 ]]> ＜10 ＜10 Comparative Example 14 <![CDATA[1.2×10 5 ]]> <![CDATA[2.5×10 4 ]]> <![CDATA[3.7×10 3 ]]> <![CDATA[2.4×10 2 ]]> ＜10 ＜10

[0109] As can be seen from Tables 9 and 10:

[0110] Taking Examples 1-3 as examples:

[0111] Bacteria showed a decrease of >4 log value after 7 days and >6 log value after 28 days; fungi showed a decrease of >2 log value after 7 days and >4 log value after 28 days. Result: Both bacteria and fungi passed the test.

[0112] Taking Comparative Examples 6, 7, and 14 as examples:

[0113] Bacteria showed a 7-day log decrease >4 and a 28-day log decrease >6; fungi showed a 7-day log decrease >1 and a 28-day log decrease >4. Result: Bacteria pass the test, fungi fail. Example 1:

[0114] Bacteria showed a decrease of <2 log value over 7 days and >4 log value over 28 days; fungi showed a decrease of >1 log value over 7 days and >4 log value over 28 days.

[0115] Results: Neither bacteria nor fungi passed the test.

[0116] Similarly, the anti-corrosion test judgment results of each example and comparative example are summarized in Table 11 as follows.

[0117] Summary of Anti-corrosion Test Judgment Results in Table 11

[0118] Bacterial test Fungal test Example 1 pass pass Example 2 pass pass Example 3 pass pass Comparative Example 1 Not approved Not approved Comparative Example 6 pass Not approved Comparative Example 7 pass Not approved Comparative Example 14 pass Not approved

[0119] Combining Tables 9 - 11, it can be seen that the cream provided by the embodiments of the present invention has good anti-corrosion effects. Among them, the effect of Example 3 is the best, and the anti-corrosion system of Example 3 is the lowest anti-corrosion ingredient dosage under the qualified anti-corrosion effect.

[0120] Test Example 3

[0121] Perform safety tests on Example 3, which showed the best performance in Test Example 1 and Test Example 2, including multiple (acute) skin irritation tests and eye irritation tests.

[0122] Multiple (Acute) Skin Irritation Test:

[0123] Test Method: Refer to the "Technical Specifications for Cosmetics Safety" 2015 Edition of CFDA;

[0124] Test Animals: Guinea pigs (female / male), body weight: 250g - 300g;

[0125] License Number for the Use of Experimental Animals in Our Hospital: SYXK (Shanghai) 2024 - 0029;

[0126] Production License Number of Shanghai Jiagan Biotechnology Co., Ltd.: SCXK (Shanghai) 2020 - 0006;

[0127] Test Conditions: Laboratory temperature is 20°C - 24°C; relative humidity is 60% - 70%;

[0128] The test results are shown in Table 12.

[0129] Table 12 Test Results [[ID=4I]]

[0130]

[0131]

[0132] Eye Irritation Test:

[0133] Test Method: Refer to the "Technical Specifications for Cosmetics Safety" 2015 Edition of CFDA;

[0134] Test Animals: Rabbits (female / male), License Number for the Use of Experimental Animals in Our Hospital: SXK (Shanghai) 2024 - 0029; Production License Number of Shanghai Jiagan Biotechnology Co., Ltd.: SCXK (Shanghai) 2020 - 0006;

[0135] Test conditions: Laboratory temperature 20℃~24℃; relative humidity 60%~70%, no rinsing. Test results are shown in Table 13.

[0136] Table 13 Test Results

[0137]

[0138]

[0139] Test Example 3 shows that Example 3 of the present invention did not show any irritant reaction in multiple (acute) skin irritation tests and eye irritation tests, indicating that it is mild and non-irritating.

[0140] In summary, this invention creatively proposes a high-content, all-naturally derived oil-based cream without emulsifiers. This cream is characterized by being emulsifier-free, low in preservatives, and high in oil content. Furthermore, it is gentle and non-irritating, possessing good stability and antibacterial effects, thus meeting the requirements of cosmetics. Its preparation method is simple, easy to operate, and suitable for industrial production.

[0141] The above description is merely a preferred embodiment of the present invention and is not intended to limit the invention. Various modifications and variations can be made to the present invention by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the scope of protection of the present invention.

Claims

1. An emulsifier-free high content pure natural source oil cream characterized in that, The preparation raw materials of the high-content pure natural source oil cream include 30-40% emollients, 5-10% humectants, 0.5-5% thickening agents, 0.01-0.2% chelating agents, 0.01-0.5% pH regulators and 0.6-1% preservatives, with the balance being water; The emollients are pure natural source oils; The thickening agents include acrylic acid (ester) / C10-30 alkanol acrylic acid ester cross-linked polymers, and the mass ratio of the acrylic acid (ester) / C10-30 alkanol acrylic acid ester cross-linked polymers in the thickening agents to the pH regulators is 1:0.9 to 1:1.1; The pH regulators are arginine.

2. The high content pure natural source oil cream of claim 1, characterized by, The preparation raw materials of the high-content pure natural source oil cream include 32-38% emollients, 6-8% humectants, 2-3% thickening agents, 0.01-0.1% chelating agents, 0.2-0.4% pH regulators and 0.6-0.8% preservatives, with the balance being water.

3. The high content pure natural source oil cream of claim 2, characterized by, The preparation raw materials of the high-content pure natural source oil cream include 32-38% emollients, 6-8% humectants, 2-3% thickening agents, 0.01-0.1% chelating agents, 0.2-0.4% pH regulators and 0.6-0.8% preservatives, with the balance being water.

4. The high content pure natural origin oil cream according to any one of claims 1 to 3, characterized in that, The emollients include at least one of squalane, coco-caprylate / caprate, jojoba seed oil and white pool flower seed oil.

5. The high content pure natural origin oil cream according to any one of claims 1 to 3, characterized in that, The humectants include at least one of glycerin, 1,3-butanediol, hyaluronic acid and hydrogenated lecithin.

6. The high content pure natural origin oil cream according to any one of claims 1 to 3, characterized in that, The thickening agents further include at least one of carbomer and cetyl stearyl alcohol.

7. The high content natural source oil cream of any one of claims 1 to 3, wherein the high content natural source oil cream is characterized by, The chelating agents include EDTA-2Na.

8. The high content pure natural source oil cream according to any one of claims 1 to 3, characterized in that, The preservatives include at least one of p-hydroxyacetophenone and 1,2-hexanediol.

9. A process for the preparation of a high content natural source oil cream as claimed in any one of claims 1 to 8, characterized in that, The method includes the following steps: The water, the humectants and the chelating agents are mixed in a certain proportion and heated to obtain a first mixture; the emollients and the thickening agents are mixed and heated to obtain a second mixture; the first mixture and the second mixture are mixed to obtain a third mixture; the pH regulators are added to the third mixture first, and then the preservatives are added.

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