An irreversible electroporation ablation assembly with a movable electrode assembly

Abstract

The present invention discloses an irreversible electroporation ablation assembly with a movable electrode assembly, which relates to the technical field of medical devices. It includes an ablation assembly main body, and the ablation assembly main body includes an ablation gun. A grip is fixedly connected to the upper surface of the ablation gun, and an extension cylinder is fixedly connected to the bottom surface of the ablation gun. An ablation needle is fixedly communicated with the bottom surface of the extension cylinder. A plurality of ablation electrodes are jointly slidably connected inside the ablation needle and inside the extension cylinder. An installation and clamping mechanism is arranged below the ablation gun. This irreversible electroporation ablation assembly with a movable electrode assembly reduces the problem of inaccurate positioning caused by the main surgeon manually inserting the assembly into the target position of the patient by setting a connection and installation unit. The assembly is installed inside the connection and installation unit and its position is located, improving the use accuracy of this irreversible electroporation ablation assembly.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and specifically to an irreversible electroporation ablation assembly with a movable electrode assembly. Background Art

[0002] Electroporation is a novel ablation technique that has the potential to overcome the main drawbacks of other ablation methods. It uses electrical pulses propagating between two or more electrodes to form "nanopores" in cell membranes. If the applied current reaches a certain threshold, these nanopores become permanent, leading to cell death. Irreversible electroporation has been proven to effectively and safely destroy tumor cells while preserving tissue structure and minimizing damage to blood vessels and important urinary system structures. One method of implementing irreversible electroporation is to insert electrode needles into the target location for treatment.

[0003] Existing irreversible electroporation ablation assemblies use the electrical pulses propagating between two or more electrodes to kill tumor cells by directly inserting them into the target location of the patient by the operating surgeon manually. However, the accuracy of inserting the assembly into the target location of the patient manually is relatively low, which easily causes the assembly to be unable to accurately destroy and kill tumor cells. Moreover, the assembly inserted into the target location of the patient is prone to shaking, which may change the position between the discharge end electrodes of the assembly, further affecting the use accuracy of the irreversible electroporation ablation assembly. For this reason, we propose an irreversible electroporation ablation assembly with a movable electrode assembly.

[0004] When we combine the above problems, we will find that it is very difficult to avoid the above-mentioned problems simultaneously when the existing irreversible electroporation ablation assemblies on the market are in use. And even if they can be solved, external tools need to be used for cooperation to solve them, thus unable to achieve the desired effect. Therefore, we propose an irreversible electroporation ablation assembly with a movable electrode assembly. Summary of the Invention

[0005] The purpose of the present invention is to provide an irreversible electroporation ablation assembly with a movable electrode assembly to solve the problems raised in the above background art.

[0006] To achieve the above purpose, the present invention provides the following technical solution: An irreversible electroporation ablation assembly with a movable electrode assembly, including an ablation assembly main body. The ablation assembly main body includes an ablation gun. A grip is fixedly connected to the upper surface of the ablation gun. An extension cylinder is fixedly connected to the bottom surface of the ablation gun. An ablation needle is fixedly communicated with the bottom surface of the extension cylinder. A plurality of ablation electrodes are slidably connected together inside the ablation needle and inside the extension cylinder. An installation and clamping mechanism is arranged below the ablation gun.

[0007] The installation and clamping mechanism includes a connection and installation unit which is located below the ablation gun and is used for stably installing the irreversible electroporation ablation assembly on the patient's body surface;

[0008] The installation and clamping mechanism includes a clamping and stabilizing unit which is located outside the extension cylinder. The connection and installation unit is used in cooperation with the clamping and stabilizing unit, and the clamping and stabilizing unit is used for stably clamping the irreversible electroporation ablation assembly;

[0009] The back surface of the clamping and stabilizing unit is provided with a precise measurement mechanism which is used in cooperation with the installation and clamping mechanism and is used for precisely measuring the extension dimension of the irreversible electroporation ablation assembly.

[0010] Preferably, the connection and installation unit includes an installation frame which is arranged outside the ablation needle. Four support cylinders are fixedly connected to the bottom surface of the installation frame. An extension tube is slidably connected to the inside of each support cylinder. A tightening nut is threadedly connected to the outer surface of each support cylinder and the outer surface of each extension tube. A vacuum suction cup is movably hinged to the bottom surface of each extension tube. A communication tube is fixedly communicated with the outer surface of each extension tube. The bottom end of each communication tube penetrates through the vacuum suction cup and extends into the inside of the vacuum suction cup. An air extraction tube is fixedly connected to the upper surface of the installation frame. The top end of each extension tube is fixedly communicated with the outer surface of the air extraction tube through a telescopic hose. A vacuum extraction tube is fixedly connected to the upper surface of the installation frame. The mutually close ends of the air extraction tubes are fixedly communicated with the outer surface of the vacuum extraction tube. A connection frame is fixedly connected to the outer surface of the installation frame. Four limit cylinders are fixedly connected to the upper surface of the connection frame. A rotation motor is arranged above the connection frame. The bottom surface of the rotation motor is in contact with the top end of the vacuum extraction tube. A sliding frame is fixedly connected to the outer surface of the rotation motor. Four limit columns are fixedly connected to the bottom surface of the sliding frame. The four limit columns are respectively slidably connected to the inside of the four limit cylinders. The output end of the rotation motor is fixedly connected to a rotation shaft. A rotation disk is fixedly connected to the outer surface of the rotation shaft. The rotation disk is rotatably connected to the inside of the vacuum extraction tube. A guiding sliding block is fixedly connected to the outer surface of the rotation disk. A guiding sliding groove is formed in the inner wall of the vacuum extraction tube. The guiding sliding block is slidably connected to the inner cavity of the guiding sliding groove. The bottom end of the rotation shaft is fixedly connected to a silica gel piston. The silica gel piston is slidably connected to the inside of the vacuum extraction tube.

[0011] Preferably, medical tapes arranged in an equidistant circular arrangement are adhered to the outer surface of each vacuum suction cup, and the adhesive surfaces of each medical tape are adhered to the patient's body surface.

[0012] Preferably, the clamping and stabilizing unit includes a stabilizing cylinder, the extension cylinder is slidably connected to the inside of the stabilizing cylinder, an upper limiting frame is sleeved outside the stabilizing cylinder, four limiting connecting rods are fixedly connected to the bottom surface of the upper limiting frame, and four connecting and reinforcing plates are fixedly connected to the inner wall of the mounting frame. The bottom ends of the four limiting connecting rods are respectively fixedly connected to the upper surfaces of the four connecting and reinforcing plates. An upper limiting ring and a conical ring are respectively fixedly connected to the outer surface of the stabilizing cylinder, and the bottom surface of the upper limiting ring is fixedly connected to the upper surface of the conical ring. A moving plate is fixedly connected to the back surface of the sliding frame, a clamping ring is fixedly connected to the back surface of the moving plate, and a plurality of clamping buckles arranged at equal distances are fixedly connected to the inner wall of the clamping ring. One side surface of each of the plurality of clamping buckles in contact with the outer surface of the conical ring.

[0013] Preferably, a lower limiting frame is fixedly connected to the side surfaces of the four connecting and reinforcing plates close to each other, and the outer surface of the stabilizing cylinder is in contact with the inner wall of the lower limiting frame.

[0014] Preferably, a lower limiting ring is arranged above the lower limiting frame, and the inner wall of the lower limiting ring is fixedly connected to the outer surface of the stabilizing cylinder.

[0015] Preferably, a sliding positioning cylinder is fixedly communicated with the bottom surface of the stabilizing cylinder, and the ablation needle is slidably connected to the inside of the sliding positioning cylinder.

[0016] Preferably, first connecting rods are fixedly connected to both side surfaces of the sliding frame, positioning sliding rings are fixedly connected to the ends of the two first connecting rods away from each other, the inner walls of the two positioning sliding rings are respectively in contact with the outer surfaces of two of the limiting connecting rods, and second connecting rods are fixedly connected to the outer surfaces of each of the positioning sliding rings. One ends of the two second connecting rods close to each other are fixedly connected to the outer surface of the clamping ring.

[0017] Preferably, the precise measurement mechanism includes a measurement fixed ring, the inner wall of the measurement fixed ring is fixedly connected to the outer surface of the ablation gun, a first measurement scale is fixedly connected to the outer surface of the measurement fixed ring, a first extension scale is slidably connected to the inside of the first measurement scale, a second measurement scale is fixedly connected to the outer surface of the lower limiting ring, a second extension scale is slidably connected to the inside of the second measurement scale, and precise scale marks are fixedly connected to the back surfaces of the first measurement scale, the first extension scale, the second measurement scale, and the second extension scale.

[0018] Preferably, bottom plates are fixedly connected to the bottom surfaces of the first extension scale and the second extension scale, and the bottom surface of one of the bottom plates is in contact with the upper surface of the second measurement scale.

[0019] Compared with the prior art, the beneficial effects of the present invention are:

[0020] 1. By providing a connection and installation unit, the present invention can stably install the irreversible electroporation ablation assembly on the patient's body surface, reducing the problem of inaccurate insertion position caused by the need for the surgeon to directly insert the irreversible electroporation ablation assembly into the target position of the patient by hand. It only needs to be stably connected to the required position on the patient's body surface through the connection and installation unit, install the irreversible electroporation ablation assembly into the connection and installation unit, and position it, so as to accurately use the irreversible electroporation ablation assembly and improve the usage accuracy of the irreversible electroporation ablation assembly.

[0021] 2. By providing a clamping and stabilizing unit, when the connection and installation unit is installed at the required position on the patient's body surface, the stabilizing cylinder for installing the irreversible electroporation ablation assembly can be stably clamped, so as to clamp and position the installation position of the irreversible electroporation ablation assembly, and avoid the problem that the position between the discharge end electrodes of the assembly changes due to the shaking of the assembly inserted into the patient's target position, further improving the usage accuracy of the irreversible electroporation ablation assembly.

[0022] 3. By providing a precise measurement mechanism, through the cooperation of the connection and installation unit and the clamping and stabilizing unit, by setting a first measuring scale and a first extension scale outside the ablation gun, and using a second measuring scale and a second extension scale outside the stabilizing cylinder, the distance between the irreversible electroporation ablation assembly and the patient's body surface can be measured, so as to conveniently and accurately determine the extension dimension of the irreversible electroporation ablation assembly, and further accurately use the irreversible electroporation ablation assembly. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 Schematic diagram of the overall structure of the present invention;

[0024] Figure 2 Schematic diagram of the bottom view structure of the vacuum suction cup of the present invention;

[0025] Figure 3 Schematic diagram of the structure of the air extraction pipe of the present invention;

[0026] Figure 4 Schematic diagram of the sectional view of the vacuum extraction pipe of the present invention;

[0027] Figure 5 Schematic diagram of the structure of the rotating motor of the present invention;

[0028] Figure 6 Schematic diagram of the structure of the stabilizing cylinder of the present invention;

[0029] Figure 7 Rear view and bottom view schematic diagram of the second measuring scale of the present invention;

[0030] Figure 8Schematic structural diagram of the ablation gun of the present invention;

[0031] Figure 9 Rear view structural diagram of the first measuring scale of the present invention.

[0032] In the figure: 1. Main body of ablation component; 11. Ablation gun; 12. Grip; 13. Extension tube; 14. Ablation needle; 15. Ablation electrode;

[0033] 2. Installation and clamping mechanism; 21. Connection and installation unit; 2101. Installation frame; 2102. Support tube; 2103. Extension tube; 2104. Tightening nut; 2105. Vacuum suction cup; 2106. Connecting pipe; 2107. Medical tape; 2108. Exhaust pipe; 2109. Connecting frame; 2110. Limiting cylinder; 2111. Exhaust vacuum tube; 2112. Limiting column; 2113. Sliding frame; 2114. Rotating motor; 2115. Rotating shaft;

[0034] 2116. Rotating disk; 2117. Guide sliding block; 2118. Silicone piston; 2119. Guide sliding groove; 22. Clamping and stabilizing unit; 2201. Connection and reinforcement plate; 2202. Limiting connecting rod; 2203. Upper limiting frame; 2204. Stabilizing cylinder; 2205. Upper limiting ring; 2206. Lower limiting ring; 2207. Sliding positioning cylinder; 2208. Conical ring; 2209. Moving plate; 2210. Clamping ring; 2211. Clamping buckle; 2212. First connecting rod; 2213. Positioning sliding ring; 2214. Second connecting rod; 2215. Lower limiting frame;

[0035] 3. Precision measurement mechanism; 301. Measurement fixing ring; 302. First measuring scale; 303. First extension scale; 304. Second measuring scale; 305. Second extension scale; 306. Lower bottom plate; 307. Precision scale. Detailed implementation manners

[0036] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention. Embodiment 1

[0037] Please refer to Figures 1-9, the present invention provides a technical solution: an irreversible electroporation ablation assembly with a movable electrode assembly, including an ablation assembly main body 1. The ablation assembly main body 1 includes an ablation gun 11. A grip 12 is fixedly connected to the upper surface of the ablation gun 11. An extension cylinder 13 is fixedly connected to the bottom surface of the ablation gun 11. An ablation needle 14 is fixedly communicated with the bottom surface of the extension cylinder 13. A plurality of ablation electrodes 15 are slidably connected together inside the ablation needle 14 and inside the extension cylinder 13. An installation and clamping mechanism 2 is arranged below the ablation gun 11. The main body of this irreversible electroporation ablation assembly is composed of the ablation gun 11, the grip 12, the extension cylinder 13, the ablation needle 14 and the ablation electrodes 15. By using the plurality of ablation electrodes 15 to slide inside the ablation needle 14 and inside the extension cylinder 13, this irreversible electroporation ablation assembly can have a movable electrode assembly, so as to facilitate the use of this irreversible electroporation ablation assembly to destroy and kill tumor cells in the patient's body;

[0038] The installation and clamping mechanism 2 includes a connection and installation unit 21. The connection and installation unit 21 is located below the ablation gun 11, and the connection and installation unit 21 is used to stably install this irreversible electroporation ablation assembly on the patient's body surface.

[0039] As a further limitation of the installation and clamping mechanism 2 of the present invention, the connection and installation unit 21 includes an installation frame 2101. The installation frame 2101 is arranged outside the ablation needle 14. Four support cylinders 2102 are fixedly connected to the bottom surface of the installation frame 2101. An extension tube 2103 is slidably connected inside each support cylinder 2102. A tightening nut 2104 is threadedly connected to the outer surface of each support cylinder 2102 and the outer surface of each extension tube 2103. A vacuum suction cup 2105 is movably hinged to the bottom surface of each extension tube 2103. A medical tape 2107 arranged in an equidistant circular arrangement is adhered to the outer surface of each vacuum suction cup 2105. The adhesive surface of each medical tape 2107 is adhered to the patient's body surface. By using the medical tape 2107 arranged on the outer surface of the vacuum suction cup 2105, it can be adhered to the patient's body surface, so as to facilitate the pre-installation of this irreversible electroporation ablation assembly to the required position on the patient's body surface, and then use the vacuum suction cup 2105 to adsorb the patient's body surface to stably install this irreversible electroporation ablation assembly to the required position on the patient's body surface.

[0040] A connecting pipe 2106 is fixedly connected to the outer surface of each extension pipe 2103. The bottom end of each connecting pipe 2106 penetrates through the vacuum suction cup 2105 and extends into the interior of the vacuum suction cup 2105. An air extraction pipe 2108 is fixedly connected to the upper surface of the mounting frame 2101. The top end of each extension pipe 2103 is fixedly connected to the outer surface of the air extraction pipe 2108 through a telescopic hose. A vacuum extraction pipe 2111 is fixedly connected to the upper surface of the mounting frame 2101. The mutually close ends of the air extraction pipes 2108 are fixedly connected to the outer surface of the vacuum extraction pipe 2111. A connecting frame 2109 is fixedly connected to the outer surface of the mounting frame 2101. Four limiting cylinders 2110 are fixedly connected to the upper surface of the connecting frame 2109. A rotating motor 2114 is arranged above the connecting frame 2109. The bottom surface of the rotating motor 2114 is in contact with the top end of the vacuum extraction pipe 2111. A sliding frame 2113 is fixedly connected to the outer surface of the rotating motor 2114. Four limiting columns 2112 are fixedly connected to the bottom surface of the sliding frame 2113. The four limiting columns 2112 are respectively slidably connected to the interiors of the four limiting cylinders 2110. By using the power provided by the rotating motor 2114, the rotating motor 2114 can be moved up and down by means of a structure, so that the four limiting columns 2112 slide in the interiors of the four limiting cylinders 2110. And by using the cooperation between the four limiting columns 2112 and the four limiting cylinders 2110, the rotation of the rotating motor 2114 is restricted, thus facilitating driving the rotating motor 2114 to move up and down.

[0041] A rotating shaft 2115 is fixedly connected to the output end of the rotating motor 2114. A rotating disc 2116 is fixedly connected to the outer surface of the rotating shaft 2115. The rotating disc 2116 is rotatably connected to the interior of the vacuum extraction pipe 2111. A guiding sliding block 2117 is fixedly connected to the outer surface of the rotating disc 2116. A guiding sliding groove 2119 is formed in the inner wall of the vacuum extraction pipe 2111. The guiding sliding block 2117 is slidably connected to the inner cavity of the guiding sliding groove 2119. A silica gel piston 2118 is fixedly connected to the bottom end of the rotating shaft 2115. The silica gel piston 2118 is slidably connected to the interior of the vacuum extraction pipe 2111. By driving the rotating disc 2116 to rotate in the interior of the vacuum extraction pipe 2111 by the rotating motor 2114, and by using the guiding sliding block 2117 to slide in the inner cavity of the guiding sliding groove 2119, the rotating disc 2116 can be driven to move up and down in the interior of the vacuum extraction pipe 2111. Thus, by using the silica gel piston 2118 to move up and down in the interior of the vacuum extraction pipe 2111, the air between the vacuum suction cup 2105 and the patient's body surface can be extracted through the vacuum extraction pipe 2111, and further the vacuum suction cup 2105 can be adsorbed on the patient's body surface, so that the irreversible electroporation ablation assembly can be stably installed at the required position.

[0042] The specific implementation manner of this embodiment is as follows: When a doctor needs to use the irreversible electroporation ablation component with a movable electrode assembly and install it at the required position on the patient's body surface to precisely destroy and kill the tumor cells in the patient's body, first, manually bring the four vacuum suction cups 2105 provided at the bottom of the component into contact with the patient's body surface, and make the position below the ablation needle 14 fixedly connected to the lower part of the extension cylinder 13 correspond to the position where the patient needs to be inserted. Then, use the multiple medical tapes 2107 pasted on the outer surface of the vacuum suction cups 2105 to paste them at the required position on the patient's body surface, so that the irreversible electroporation ablation component can be pre-installed at the required position on the patient's body surface. Next, manually move the extension tube 2103 sliding in the support cylinder 2102 to adjust the distance between the mounting frame 2101 and the patient's body surface, and then manually twist and tighten the nut 2104 to fix the relative position between the support cylinder 2102 and the extension tube 2103. Since the extension tube 2103 is spherically hinged to the vacuum suction cup 2105, the vacuum suction cup 2105 can fit the complex body surface of the patient. Then, control the power supply of the rotation motor 2114 through the PLC controller, and use the rotation motor 2114 to drive the rotation shaft 2115 to rotate. Since the rotation shaft 2115 drives the rotation disk 2116 and the silicone piston 2118 to rotate in the extraction vacuum tube 2111, and the guiding sliding block 2117 fixedly installed on the outer surface of the rotation disk 2116 cooperates with the guiding sliding groove 2119 in the extraction vacuum tube 2111, and through the sliding frame 2113 fixedly installed outside the rotation motor 2114, and the limiting column 2112 fixedly installed below the sliding frame 2113 slides in the limiting cylinder 2110 fixedly installed on the connecting frame 2109, the rotation of the rotation motor 2114 can be limited, and only the rotation motor 2114 can be used to drive the rotation shaft 2115, the rotation disk 2116 and the silicone piston 2118 to slide in the extraction vacuum tube 2111. Since the silicone piston 2118 is in interference fit with the extraction vacuum tube 2111, the air between the vacuum suction cup 2105 and the patient's body surface can be transported into the extraction vacuum tube 2111 through the extension tube 2103, the connecting tube 2106 and the extraction tube 2108 by the movement of the silicone piston 2118 until the air between the vacuum suction cup 2105 and the patient's body surface is evacuated, so that the vacuum suction cup 2105 can be firmly adsorbed on the patient's body surface, and thus the irreversible electroporation ablation component can be stably installed on the patient's skin surface, and the irreversible electroporation ablation component can be used to treat the patient precisely and stably. Embodiment Two

[0043] Please refer to Figures 1-9 , the present invention provides a technical solution: an irreversible electroporation ablation component with a movable electrode assembly, and the present invention makes corresponding improvements to the technical problems mentioned in the background art.

[0044] As a further limitation of the installation and clamping mechanism 2 of the present invention, the installation and clamping mechanism 2 includes a clamping and stabilizing unit 22. The clamping and stabilizing unit 22 is located outside the extension cylinder 13. The connecting and installing unit 21 and the clamping and stabilizing unit 22 are used in cooperation. The clamping and stabilizing unit 22 is used for stably clamping the irreversible electroporation ablation assembly.

[0045] The clamping and stabilizing unit 22 includes a stabilizing cylinder 2204. The extension cylinder 13 is slidably connected to the inside of the stabilizing cylinder 2204. The bottom surface of the stabilizing cylinder 2204 is fixedly communicated with a sliding positioning cylinder 2207. The ablation needle 14 is slidably connected to the inside of the sliding positioning cylinder 2207. Through the stabilizing cylinder 2204, the extension cylinder 13 can slide inside it, so that the ablation needle 14 fixed to the bottom surface of the extension cylinder 13 can slide inside the sliding positioning cylinder 2207 fixed to the bottom surface of the stabilizing cylinder 2204, facilitating the use of the ablation needle 14 to insert into the patient's body to destroy and kill tumor cells.

[0046] An upper limit frame 2203 is sleeved outside the stabilizing cylinder 2204. Four limit connecting rods 2202 are fixedly connected to the bottom surface of the upper limit frame 2203. Four connecting and reinforcing plates 2201 are fixedly connected to the inner wall of the mounting frame 2101. The bottom ends of the four limit connecting rods 2202 are respectively fixedly connected to the upper surfaces of the four connecting and reinforcing plates 2201. The side surfaces of the four connecting and reinforcing plates 2201 close to each other are fixedly connected to a lower limit frame 2215 together. The outer surface of the stabilizing cylinder 2204 is in contact with the inner wall of the lower limit frame 2215. By using the lower limit frame 2215, the moving stabilizing cylinder 2204 can be limited, thereby improving the up and down movement stability of the stabilizing cylinder 2204.

[0047] A lower limit ring 2206 is arranged above the lower limit frame 2215. The inner wall of the lower limit ring 2206 is fixedly connected to the outer surface of the stabilizing cylinder 2204. By fixing the lower limit ring 2206 to the outer surface of the stabilizing cylinder 2204, the movement of the stabilizing cylinder 2204 can be stably limited by the contact between the lower limit ring 2206 and the lower limit frame 2215.

[0048] The outer surface of the stabilizing cylinder 2204 is fixedly connected with an upper limit ring 2205 and a conical ring 2208 respectively. The bottom surface of the upper limit ring 2205 is fixedly connected with the upper surface of the conical ring 2208. The back surface of the sliding frame 2113 is fixedly connected with a moving plate 2209. The back surface of the moving plate 2209 is fixedly connected with a clamping ring 2210. The inner wall of the clamping ring 2210 is fixedly connected with clamping buttons 2211 arranged at equal distances. One side surfaces of a plurality of clamping buttons 2211 close to each other are all in contact with the outer surface of the conical ring 2208. Both side surfaces of the sliding frame 2113 are fixedly connected with first connecting rods 2212. One ends of the two first connecting rods 2212 far away from each other are both fixedly connected with positioning sliding rings 2213. The inner walls of the two positioning sliding rings 2213 are respectively in contact with the outer surfaces of two of the limiting connecting rods 2202. The outer surface of each positioning sliding ring 2213 is fixedly connected with a second connecting rod 2214. One ends of the two second connecting rods 2214 close to each other are both fixedly connected with the outer surface of the clamping ring 2210. By fixing the positioning sliding rings 2213 between the two first connecting rods 2212 and the two second connecting rods 2214, it is possible to make the positioning sliding rings 2213 slide on the outer surfaces of the limiting connecting rods 2202, so that the sliding frame 2113 can stably drive the clamping ring 2210 to move up and down.

[0049] The specific implementation manner of this embodiment is as follows: While using the power provided by the rotating motor 2114 to firmly attach and fix the vacuum suction cup 2105 to the patient's body surface, by manually placing the stabilizing cylinder 2204 inside the upper limiting frame 2203 and the lower limiting frame 2215, the stabilizing cylinder 2204 can slide inside the upper limiting frame 2203 and the lower limiting frame 2215. And by using the limiting connecting rod 2202 and the connecting reinforcement plate 2201, the upper limiting frame 2203 and the lower limiting frame 2215 are connected to the mounting frame 2101, so that the clamping and stabilizing unit 22 can be connected to the connecting and mounting unit 21. Then, by moving the sliding frame 2113 upward, the clamping ring 2210 is connected to the sliding frame 2113 by using the moving plate 2209, and the clamping ring 2210 is further connected to the sliding frame 2113 by the first connecting rod 2212, the positioning sliding ring 2213 and the second connecting rod 2214. At the same time, the positioning sliding ring 2213 slides along the outer surface of the limiting connecting rod 2202, and the clamping ring 2210 slides along the outer surface of the stabilizing cylinder 2204. Since a plurality of compressible clamping buttons 2211 are fixed on the inner wall of the clamping ring 2210, and a conical ring 2208 is fixed on the outer surface of the stabilizing cylinder 2204, the clamping ring 2210 can be used to firmly clamp the stabilizing cylinder 2204 by the extrusion of the clamping buttons 2211 and the conical ring 2208 until the clamping ring 2210 contacts the bottom surface of the upper limiting ring 2205, and the upper surface of the upper limiting ring 2205 contacts the bottom surface of the upper limiting frame 2203, so that the stabilizing cylinder 2204 can be stably clamped, and thus the outer surfaces of the extension cylinder 13 and the ablation needle 14 can be stably clamped and limited, further avoiding the problem that the position between the discharge end electrodes of the component changes due to the shaking of the component inserted into the target position of the patient. Embodiment III

[0050] Please refer to Figures 1-9 , the present invention provides a technical solution: an irreversible electroporation ablation assembly with a movable electrode assembly, and the present invention makes corresponding improvements to the technical problems mentioned in the background art.

[0051] As a further limitation of the mounting and clamping mechanism 2 of the present invention, a precise measurement mechanism 3 is provided on the back of the clamping and stabilizing unit 22. The precise measurement mechanism 3 is used in cooperation with the mounting and clamping mechanism 2, and the precise measurement mechanism 3 is used to precisely measure the extension dimension of the irreversible electroporation ablation assembly.

[0052] The precise measurement mechanism 3 includes a measurement fixing ring 301. The inner wall of the measurement fixing ring 301 is fixedly connected to the outer surface of the ablation gun 11. A first measuring scale 302 is fixedly connected to the outer surface of the measurement fixing ring 301. A first extension scale 303 is slidably connected inside the first measuring scale 302. Through the first measuring scale 302 and the first extension scale 303, the distance between the measurement fixing ring 301 fixed on the outer surface of the ablation gun 11 and the lower limit ring 2206 can be measured, so as to conveniently and precisely control the extension and movement dimension of the irreversible electroporation ablation assembly.

[0053] A second measuring scale 304 is fixedly connected to the outer surface of the lower limit ring 2206. A second extension scale 305 is slidably connected inside the second measuring scale 304. The bottom surfaces of the first extension scale 303 and the second extension scale 305 are both fixedly connected to a lower bottom plate 306. The bottom surface of one of the lower bottom plates 306 is in contact with the upper surface of the second measuring scale 304. Through the second measuring scale 304 and the second extension scale 305, the distance between the lower limit ring 2206 and the patient's body surface can be measured, so as to further conveniently and precisely control the extension and movement dimension of the irreversible electroporation ablation assembly.

[0054] Precise scale marks 307 are fixedly connected to the back surfaces of the first measuring scale 302, the first extension scale 303, the second measuring scale 304, and the second extension scale 305. By using the precise scale marks 307 fixed on the surfaces of the first measuring scale 302, the first extension scale 303, the second measuring scale 304, and the second extension scale 305, it is convenient to read the dimensions of the first measuring scale 302, the first extension scale 303, the second measuring scale 304, and the second extension scale 305, so as to conveniently and precisely read the extension and movement dimension of the irreversible electroporation ablation assembly.

[0055] The specific implementation of this embodiment is as follows: After clamping, limiting and fixedly installing the main body of the irreversible electroporation ablation assembly composed of the ablation gun 11, the grip 12, the extension cylinder 13, the ablation needle 14 and the ablation electrode 15, it is necessary to manually pull the second extension ruler 305 in the second measuring ruler 304 to enable the second extension ruler 305 to slide in the second measuring ruler 304. By reading the precise scale 307 fixed on one side of the second measuring ruler 304 and the second extension ruler 305, the distance between the lower limit ring 2206 fixed outside the stable cylinder 2204 and the patient's body surface can be read. At the same time, by manually pulling the lower base plate 306, the first extension ruler 303 slides in the first measuring ruler 302 until the bottom surface of the lower base plate 306 contacts the upper surface of the second measuring ruler 304. Thus, by reading the precise scale 307 fixed on one side of the first measuring ruler 302 and the first extension ruler 303, the distance between the measurement fixing ring 301 fixed outside the ablation gun 11 and the body surface of the lower limit ring 2206 can be read, and further the distance between the measurement fixing ring 301 fixed outside the ablation gun 11 and the patient's body surface can be accurately read. By manually holding the grip 12, the extension cylinder 13 can slide in the stable cylinder 2204 through the ablation gun 11, and the ablation needle 14 fixedly connected to the lower part of the extension cylinder 13 slides in the sliding positioning cylinder 2207 until the bottom end of the ablation needle 14 contacts the patient's skin surface. At this time, the distance between the measurement fixing ring 301 fixed outside the ablation gun 11 and the patient's body surface is accurately read. By manually holding the grip 12 and pushing the ablation gun 11, the distance that the ablation needle 14 extends into the patient's body can be accurately read, and further the irreversible electroporation ablation assembly can be accurately used on the patient's body until the ablation electrode 15 in the ablation needle 14 extends and distributes around the patient's tumor cells. By controlling the irreversible electroporation ablation assembly, the electrical pulses propagated between multiple ablation electrodes 15 form "nanopores" in the cell membrane. If the applied current reaches a certain threshold, these nanopores will become permanent, resulting in cell death. Irreversible electroporation has been proven to effectively and safely destroy tumor cells.

[0056] It should be noted that in this article, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the term "comprising", "including" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device comprising a series of elements not only includes those elements, but also includes other elements not expressly listed, or also includes elements inherent to such process, method, article or device.

[0057] Although embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An irreversible electroporation ablation assembly with a movable electrode assembly, comprising an ablation assembly body (1), characterized in that: The ablation assembly body (1) comprises an ablation gun (11), the upper surface of the ablation gun (11) is fixedly connected to a handle (12), the bottom surface of the ablation gun (11) is fixedly connected to an extension tube (13), the bottom surface of the extension tube (13) is fixedly connected to an ablation needle (14), the interior of the ablation needle (14) and the interior of the extension tube (13) are slidably connected to a plurality of ablation electrodes (15), and a mounting clamping mechanism (2) is provided below the ablation gun (11); The mounting clamping mechanism (2) comprises a connecting and mounting unit (21), the connecting and mounting unit (21) being located below the ablation gun (11), and the connecting and mounting unit (21) being used to stably mount the irreversible electroporation ablation component on the patient's body surface; The installation clamping mechanism (2) comprises a clamping and stabilizing unit (22), the clamping and stabilizing unit (22) being located outside the extension tube (13), the connection installation unit (21) being used in conjunction with the clamping and stabilizing unit (22), the clamping and stabilizing unit (22) being used to stably clamp the irreversible electroporation ablation component; The back of the clamping and stabilizing unit (22) is provided with a precise measuring mechanism (3), the precise measuring mechanism (3) is used in conjunction with the mounting clamping mechanism (2), and the precise measuring mechanism (3) is used to precisely measure the extension size of the irreversible electroporation ablation component; the connecting and mounting unit (21) comprises a mounting frame (2101), the outer surface of the mounting frame (2101) is fixedly connected to a connecting frame (2109), a rotating motor (2114) is provided above the connecting frame (2109), and the outer surface of the rotating motor (2114) is fixedly connected to a sliding frame (2113); The clamping and stabilizing unit (22) comprises a stabilizing cylinder (2204), the extension cylinder (13) is slidably connected to the interior of the stabilizing cylinder (2204), an upper limit frame (2203) is sleeved on the exterior of the stabilizing cylinder (2204), four connecting reinforcement plates (2201) are fixedly connected to the inner wall of the mounting frame (2101), and an upper limit ring (2205) and a conical ring (2208) are respectively fixedly connected to the outer surface of the stabilizing cylinder (2204), the upper limit ring The bottom surface of (2205) is fixedly connected to the upper surface of the conical ring (2208), the back surface of the sliding frame (2113) is fixedly connected to a moving plate (2209), the back surface of the moving plate (2209) is fixedly connected to a clamping ring (2210), the inner wall of the clamping ring (2210) is fixedly connected to clamping buckles (2211) arranged at equal distances, and the side surfaces of a plurality of the clamping buckles (2211) that are close to each other are in contact with the outer surface of the conical ring (2208); A lower limit frame (2215) is fixedly connected to one side of the four connecting reinforcement plates (2201) that are close to each other, and the outer surface of the stabilizing cylinder (2204) is in contact with the inner wall of the lower limit frame (2215); A lower limiting ring (2206) is arranged above the lower limiting frame (2215), and the inner wall of the lower limiting ring (2206) is fixedly connected to the outer surface of the stabilizing cylinder (2204); The bottom surface of the stabilizing cylinder (2204) is fixedly connected to a sliding positioning cylinder (2207), and the ablation needle (14) is slidably connected to the interior of the sliding positioning cylinder (2207).

2. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 1, characterized in that: The mounting frame (2101) is arranged on the outside of the ablation needle (14), and the bottom surface of the mounting frame (2101) is fixedly connected with four support tubes (2102), and the interior of each support tube (2102) is slidably connected with an extension tube (2103), and the outer surface of each support tube (2102) and the outer surface of each extension tube (2103) are threadedly connected with a tightening nut (2104), and the bottom surface of each extension tube (2103) is movably hinged with a vacuum suction cup (2105), and the outer surface of each extension tube (2103) is fixedly connected with a A connecting tube (2106) is provided, the bottom end of each connecting tube (2106) passes through the vacuum suction cup (2105) and extends to the interior of the vacuum suction cup (2105), the upper surface of the mounting frame (2101) is fixedly connected to an exhaust pipe (2108), the top end of each extension pipe (2103) is fixedly connected to the outer surface of the exhaust pipe (2108) through a telescopic hose, the upper surface of the mounting frame (2101) is fixedly connected to a vacuum pipe (2111), and the ends of the exhaust pipes (2108) that are close to each other are connected to the ends of the vacuum pipe (2111). The outer surface is fixedly connected, the upper surface of the connecting frame (2109) is fixedly connected to four limiting cylinders (2110), the bottom surface of the rotating motor (2114) is in contact with the top of the vacuum tube (2111), the bottom surface of the sliding frame (2113) is fixedly connected to four limiting columns (2112), the four limiting columns (2112) are respectively slidably connected to the inside of the four limiting cylinders (2110), the output end of the rotating motor (2114) is fixedly connected to a rotating shaft (2115), and the outer surface of the rotating shaft (2115) is fixedly connected to a rotating disk (2116), the rotating disk (2116) is rotatably connected to the inside of the vacuum tube (2111), the outer surface of the rotating disk (2116) is fixedly connected to a guide sliding block (2117), the inner wall of the vacuum tube (2111) is provided with a guide sliding groove (2119), the guide sliding block (2117) is slidably connected to the inner cavity of the guide sliding groove (2119), the bottom end of the rotating shaft (2115) is fixedly connected to a silicone piston (2118), and the silicone piston (2118) is slidably connected to the inside of the vacuum tube (2111).

3. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 2, characterized in that: The outer surface of each vacuum suction cup (2105) is adhered with medical tapes (2107) arranged in a circumferential manner at equal distances, and the adhesive surface of each medical tape (2107) is adhered to the patient's body surface.

4. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 2, characterized in that: Four limit connecting rods (2202) are fixedly connected to the bottom surface of the upper limit frame (2203), and the bottom ends of the four limit connecting rods (2202) are respectively fixedly connected to the upper surfaces of four connecting reinforcement plates (2201).

5. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 4, characterized in that: Both side surfaces of the sliding frame (2113) are fixedly connected to first connecting rods (2212); the ends of the two first connecting rods (2212) that are away from each other are fixedly connected to positioning slip rings (2213); the inner walls of the two positioning slip rings (2213) are respectively in contact with the outer surfaces of two of the limiting connecting rods (2202); the outer surface of each positioning slip ring (2213) is fixedly connected to a second connecting rod (2214); the ends of the two second connecting rods (2214) that are close to each other are fixedly connected to the outer surface of the clamping ring (2210).

6. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 5, characterized in that: The precise measuring mechanism (3) comprises a measuring fixing ring (301), the inner wall of which is fixedly connected to the outer surface of the ablation gun (11), the outer surface of the measuring fixing ring (301) is fixedly connected to a first measuring ruler (302), the interior of the first measuring ruler (302) is slidably connected to a first extension ruler (303), the outer surface of the lower limit ring (2206) is fixedly connected to a second measuring ruler (304), the interior of the second measuring ruler (304) is slidably connected to a second extension ruler (305), and the back sides of the first measuring ruler (302), the first extension ruler (303), the second measuring ruler (304) and the second extension ruler (305) are all fixedly connected to a precise scale ruler (307).

7. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 6, characterized in that: The bottom surface of the first extension ruler (303) and the bottom surface of the second extension ruler (305) are both fixedly connected to a lower bottom plate (306), wherein the bottom surface of one of the lower bottom plates (306) is in contact with the upper surface of the second measuring ruler (304).

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