Glycosylated hemoglobin analyzer
By designing a fully automated glycated hemoglobin analyzer, the problem of diabetes diagnosis methods in the prior art is affected by external factors, and efficient and accurate glycated hemoglobin detection is achieved, which is suitable for blood sugar management in diabetic patients.
Patent Information
- Application Number
- CN202411555747.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-04
- Publication Date
- 2025-02-14
AI Technical Summary
The existing diabetes diagnosis methods are easily affected by the diet and drugs of the patient during the random inspection period, and cannot objectively reflect the true condition of the patient's blood sugar. The analyzer used on the market for detecting glycated hemoglobin is complex in operation, has low detection efficiency and low accuracy.
A glycated hemoglobin analyzer was designed, adopting fully automated operations, including sample carrying components, sample delivery components, plunger pump mechanism and light source components. Through the automated sample delivery, liquid absorption and detection process, detection without human intervention is achieved. .
The fully automated operation of glycated hemoglobin detection is achieved, which improves the accuracy and efficiency of the detection, reduces the errors of human intervention, and can more accurately reflect the patient's average blood sugar level in the past 8-12 weeks.
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Figure CN119438608A_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of biochemical detection equipment, and in particular to a glycated hemoglobin analyzer. Background Art
[0002] Glycated hemoglobin (HbA1c) is the product of the combination of hemoglobin in red blood cells and sugars (mainly glucose) in serum through non-enzymatic reactions. The key to the treatment of diabetes is the control and stabilization of blood sugar levels. Currently, the diagnosis of diabetes is mainly based on the detection of fasting blood sugar levels and 2 hours after meals. However, it is easily affected by the patient's diet and medication during the sampling period, and cannot objectively reflect the true situation of blood sugar in the patient's body.
[0003] The non-enzymatic reaction that forms glycosylated hemoglobin is continuous, slow, and irreversible. Therefore, the content of glycosylated hemoglobin is determined by the past rather than the immediate blood sugar concentration, and has nothing to do with whether the patient is fasting before the test, whether insulin is injected, whether hypoglycemic drugs are taken, etc. It is generally believed that the concentration of glycosylated hemoglobin can effectively reflect the average blood sugar level in the past 8-12 weeks.
[0004] In actual use, analyzers currently used on the market to detect glycated hemoglobin concentration require human intervention in multiple steps, making the entire process complicated, the detection efficiency low, and the accuracy of the test results low. Summary of the invention
[0005] The present application aims to provide a glycated hemoglobin analyzer that can achieve fully automated operation without human intervention, making the detection process more accurate and efficient.
[0006] The present application provides a glycated hemoglobin analyzer, comprising:
[0007] At least one sample carrying component, the sample carrying component is used to carry a reagent strip loaded with a sample and a pipette tip;
[0008] At least one sample delivery component, the sample delivery component is in driving connection with the sample carrying component, and is used to move the sample carrying component to the first position and the second position respectively;
[0009] At least one plunger pump mechanism, the plunger pump mechanism includes a first drive component, a connecting component, a second drive component, a suction component and a piercing member, the first drive component is transmission-connected to the connecting component, the second drive component is fixed to the connecting component, the suction component is transmission-connected to the second drive component, the piercing member is fixedly installed on the connecting component, and the suction component faces the liquid-pipette head on the reagent strip in the first position, and the piercing member faces the reagent strip in the first position; the first drive component is used to drive the connecting component to move toward or away from the first position, so as to drive the piercing member to pierce the film on the reagent strip when moving toward the first position, and connect the suction component to the liquid-pipette head; the second drive component is used to drive the suction component to reciprocate in the first stroke toward or away from the first position, so as to make the suction component reciprocate to suck and discharge;
[0010] At least one light source assembly is disposed above the second position and is used to emit a detection light source to the sample for detection.
[0011] In one embodiment, the plunger pump mechanism also includes a liquid withdrawal head assembly, which is movably connected to the suction assembly and is transmission-connected to the second drive assembly. The second drive assembly is also used to drive the liquid withdrawal head assembly to move toward or away from the first position within a second stroke to push against the liquid suction head and disengage from the suction assembly; the length of the second stroke is greater than the length of the first stroke.
[0012] In one embodiment, the suction assembly includes an outer tube, a plug rod assembly and a pump head, the outer tube is fixed to the connecting assembly, the plug rod assembly is reciprocatably arranged inside the outer tube and connected to the second driving assembly, the pump head is connected to the plug rod assembly, and a cavity is provided inside the pump head; the pump head can cover the liquid suction head when moving toward the liquid suction head in the first position; the second driving assembly drives the plug rod assembly to reciprocate along the axial direction of the outer tube to generate negative pressure in the cavity; the liquid suction head assembly is movably connected to the pump head.
[0013] In one embodiment, the liquid withdrawal head assembly includes a push cylinder and a push rod, the push cylinder is sleeved on the outside of the pump head and connected to one end of the push rod, and the other end of the push rod is connected to the second driving assembly.
[0014] In one embodiment, the plug rod assembly includes a plug rod, a plug rod head and an elastic member, the plug rod head is reciprocatably disposed inside the outer tube, the plug rod is connected to the plug rod head, and the elastic member is disposed between the plug rod head and the outer tube.
[0015] In one embodiment, the stopper rod assembly further comprises a sealing member, and the sealing member is disposed between the stopper rod head and the inner wall of the outer tube.
[0016] In one embodiment, the sample carrying assembly includes a reagent strip support seat and a mounting seat, the reagent strip support seat is fixed to the mounting seat, and the mounting seat is transmission-connected to the sample delivery assembly; the reagent strip support seat is used to install a reagent strip loaded with a sample and a pipette head.
[0017] In one embodiment, the sample carrying assembly further includes a heating module, and the heating module is installed on the reagent strip support seat for heating the reagent strip.
[0018] In one embodiment, the sample delivery component includes a sample delivery drive, a sample delivery screw and a sample delivery transmission component. The sample delivery drive is transmission-connected to the sample delivery screw, the mounting seat is threadedly connected to the sample delivery screw, and the mounting seat is slidingly connected to the sample delivery transmission component. The sample delivery drive is used to drive the sample delivery screw to rotate around its axis, and the mounting seat can convert the rotational motion of the sample delivery screw into a linear movement along the axis of the sample delivery screw, and move to the first position and the second position.
[0019] In one embodiment, the light source assembly includes a light source frame, a support frame, a light source fixing plate and a light source circuit board, wherein the light source fixing plate is fixed on the support frame, the light source circuit board is connected to the support frame, the light source circuit board is arranged above the light source frame and fixedly connected to the light source fixing plate, and the light source circuit board is located above the second position; the light source circuit board is provided with a light source transmitting module and a light source receiving module, the light source transmitting module is used to transmit detection light to the sample and reagent in the reagent strip, and the light source receiving module is used to receive reflected light reflected by the sample and reagent.
[0020] According to the glycated hemoglobin analyzer of the above embodiment, when the sample delivery component drives the sample carrying component to move to the first position, the first drive component drives the connecting component to move toward or away from the first position, so that when the connecting component moves toward the first position, the piercing member can be driven by the connecting component to pierce the film on the reagent strip, and at the same time, the connecting component drives the suction component to move toward the first position to connect the liquid pipette head, and then the second drive component drives the suction component to move back and forth in the first stroke toward or away from the first position, so that the suction component can reciprocate to suck and spit to mix the sample and the reagent. In this way, the sample delivery and detection steps are automated processes, so that fully automated operation can be achieved without human intervention, making the detection process more accurate and efficient. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] Figure 1A three-dimensional diagram of the glycated hemoglobin analyzer provided for this application;
[0022] Figure 2 A three-dimensional diagram of the plunger pump mechanism in the glycosylated hemoglobin analyzer provided in the present application;
[0023] Figure 3 A cross-sectional view of the plunger pump mechanism in the glycosylated hemoglobin analyzer provided in the present application;
[0024] Figure 4 A three-dimensional diagram of a combination of a sample carrying component and a sample delivery component in a glycosylated hemoglobin analyzer provided in the present application;
[0025] Figure 5 A three-dimensional diagram of a sample carrying assembly in a glycated hemoglobin analyzer provided in the present application;
[0026] Figure 6 An exploded view of a sample carrying component in a glycated hemoglobin analyzer provided in the present application;
[0027] Figure 7 A three-dimensional diagram of a light source assembly in a glycated hemoglobin analyzer provided in the present application;
[0028] Figure 8 This is an exploded view of the light source assembly in the glycated hemoglobin analyzer provided in the present application. DETAILED DESCRIPTION
[0029] The present application is further described in detail below by specific embodiments in conjunction with the accompanying drawings. Wherein similar elements in different embodiments adopt associated similar element numbers. In the following embodiments, many detailed descriptions are intended to enable the present application to be better understood. However, those skilled in the art can easily recognize that some of the features can be omitted in different situations, or can be replaced by other elements, materials, and methods. In some cases, some operations related to the present application are not shown or described in the specification, in order to avoid the core part of the present application being overwhelmed by too much description, and for those skilled in the art, it is not necessary to describe these related operations in detail, and they can fully understand the related operations based on the description in the specification and the general technical knowledge in the art.
[0030] In addition, the features, operations or characteristics described in the specification can be combined in any appropriate manner to form various implementations, and the operation steps involved in each embodiment can also be replaced or adjusted in a sequence in a manner that is obvious to those skilled in the art. Therefore, the specification and drawings are only for the purpose of clearly describing a certain embodiment and do not mean that the composition and / or sequence are necessary.
[0031] The serial numbers of the components in this document, such as "first", "second", etc., are only used to distinguish the objects described and do not have any order or technical meaning. The "connection" and "coupling" mentioned in this application, unless otherwise specified, include direct and indirect connections (couplings).
[0032] See also Figure 1-Figure 6 As shown, the glycated hemoglobin analyzer provided by the present application includes: at least one sample carrying component 10, at least one sample delivery component 20, at least one plunger pump mechanism 30 and at least one light source component 40, wherein the at least one sample carrying component 10, the at least one sample delivery component 20, the at least one plunger pump mechanism 30 and the at least one light source component 40 correspond to each other one by one, the sample carrying component 10 is used to carry a reagent strip 100 loaded with a sample and a pipette head 101, the sample delivery component 20 is transmission-connected to the sample carrying component 10, the sample delivery component 20 is used to move the sample carrying component 10 to a first position and a second position respectively, the plunger pump mechanism 30 is arranged at the first position, and the light source component 40 is arranged at the second position, wherein the plunger pump mechanism 30 can aspirate and mix the sample at the first position, and the light source component 40 can irradiate the sample with a detection light source at the second position to detect the concentration of the sample.
[0033] In this embodiment, the sample is blood, and the concentration of glycated hemoglobin in the blood can be detected by the glycated hemoglobin analyzer.
[0034] In this application, the sample delivery and testing steps are all automated processes, so the entire process can be automated without the need for human intervention, making the testing process more accurate and efficient.
[0035] In some embodiments, two of the sample holding assembly 10, the sample delivery assembly 20, the plunger pump mechanism 30, and the light source assembly 40 can be provided, thereby forming a dual-channel analyzer to improve detection efficiency.
[0036] Of course, multiple numbers of sample carrying components 10, sample delivery components 20, plunger pump mechanisms 30 and light source components 40 may be provided according to actual needs, and the number of such components is not limited herein.
[0037] See also Figure 1 As shown, the glycated hemoglobin analyzer provided in the present application also includes a power supply assembly 50 and a base 60, wherein the sample holding assembly 10, the sample delivery assembly 20, the plunger pump mechanism 30, the light source assembly 40 and the power supply assembly 50 are all arranged on the base 60, and the sample holding assembly 10, the sample delivery assembly 20, the plunger pump mechanism 30 and the light source assembly 40 are all electrically connected to the power supply assembly 50, which can provide electrical energy for the operation of each structure.
[0038] Continue to see Figure 1As shown, the plunger pump mechanism 30 includes a first drive component 31, a connecting component 32, a second drive component 33, a suction component 34 and a piercing member 35. The first drive component 31 is transmission-connected to the connecting component 32, the second drive component 33 is fixed to the connecting component 32, the suction component 34 is transmission-connected to the second drive component 33, the piercing member 35 is fixedly installed on the connecting component 32, and the suction component 34 is oriented toward the pipette head 101 on the reagent strip 100 in the first position, and the piercing member 35 is oriented toward the reagent strip 100 in the first position.
[0039] In this embodiment, a thin film is provided on the reagent strip 100, and the first driving component 31 is used to drive the connecting component 32 to move toward or away from the first position, so that when moving toward the first position, the piercing member 35 is driven by the connecting component 32 to pierce the thin film on the reagent strip 100, and the suction component 34 is connected to the liquid pipetting head 101. The second driving component 33 is used to drive the suction component 34 to reciprocate in the direction toward or away from the first position within the first stroke, so that the suction component 34 reciprocates to suck and discharge.
[0040] In a specific embodiment, when the sample delivery component 20 drives the sample carrying component 10 to move to the first position, the first driving component 31 drives the connecting component 32 to move toward or away from the first position, so that when the connecting component 32 moves toward the first position, the piercing member 35 can be driven by the connecting component 32 to pierce the film on the reagent strip 100, and at the same time, the suction component 34 is driven by the connecting component 32 to move toward the first position to connect the pipette head 101. After that, the second driving component 33 drives the suction component 34 to reciprocate in the first stroke toward or away from the first position, so that the suction component 34 can be reciprocated to suck and discharge to mix the sample and the reagent.
[0041] In particular, the first stroke of the suction component 34 driven by the second driving component 33 can prevent the suction component 34 from colliding with the sample carrying component 10.
[0042] After the second driving component 33 drives the suction component 34 to move back and forth in the first stroke to complete the mixing of the sample and the reagent, the liquid pipetting head 101 needs to be detached from the suction component 34. Figure 2 As shown, the plunger pump mechanism 30 provided in this embodiment also includes a liquid withdrawal head assembly 36, which is movably connected to the suction assembly 34 and is transmission-connected to the second drive assembly 33. The second drive assembly 33 is also used to drive the liquid withdrawal head assembly 36 to move toward or away from the first position within the second stroke to push against the liquid suction head 101 and disengage from the suction assembly 34, wherein the length of the second stroke is greater than the length of the first stroke.
[0043] In actual use, the second driving component 33 drives the suction component 34 to move back and forth in the direction toward or away from the first position within the first stroke, so that the suction component 34 can reciprocate to suck and discharge, and in this process, it can avoid collision with the sample-carrying component 10. When the liquid head 101 needs to be withdrawn, the second driving component 33 drives the liquid head withdrawal component 36 to move in the direction toward or away from the first position within the second stroke, and the stroke of the liquid head withdrawal component 36 needs to be greater than the stroke of the suction component 34. Similarly, the second stroke of the liquid head withdrawal component 36 can avoid collision with the sample-carrying component 10.
[0044] See also Figure 2 As shown, the connecting assembly 32 is also provided with a moving block 321, and is also provided with a first limiting unit 322, a second limiting unit 323 and a third limiting unit 324, wherein the first limiting unit 322 is electrically connected to the first driving assembly 31 to limit the stroke of driving the connecting assembly 32 to move away from the first position. The second driving assembly 33 is electrically connected to the second limiting unit 323 and the third limiting unit 324, and the second limiting unit 323 can limit the stroke of the second driving assembly 33 driving the suction assembly 34 and the de-absorption head assembly 36 away from the first position, which is the starting position of the suction and de-absorption head 101, and the third limiting unit 324 can be used to limit the stroke of the second driving assembly 33 driving the suction assembly 34 to move toward the first position to prevent the suction assembly from being damaged by collision.
[0045] See also Figure 3 As shown, the suction assembly 34 includes an outer cylinder 341, a plug rod assembly 342 and a pump head 343. The outer cylinder 341 is fixed to the connecting assembly 32. The plug rod assembly 342 is reciprocatably arranged inside the outer cylinder 341 and connected to the second driving assembly 33. The pump head 343 is connected to the plug rod assembly 342, and a cavity 3431 is provided inside the pump head 343. The pump head 343 can cover the liquid suction head 101 when moving toward the liquid suction head 101 in the first position, so that the pump head 343 is connected to the liquid suction head 101. The second driving assembly 33 drives the plug rod assembly 342 to reciprocate along the axial direction of the outer cylinder 341, so that the cavity 3431 generates negative pressure, thereby performing the suction and exhalation action. The aforementioned liquid withdrawal head assembly 36 is movably connected to the pump head 343.
[0046] The liquid withdrawal head assembly 36 includes a push cylinder 361 and a push rod 362 . The push cylinder 361 is sleeved on the outside of the pump head 343 and connected to one end of the push rod 362 . The other end of the push rod 362 is connected to the second driving assembly 33 .
[0047] In a specific embodiment, an upper sleeve 3611 is further provided on the push cylinder 361 , and the upper sleeve 3611 is connected to the push rod 362 . A connecting plate 363 is further provided at the power output end of the second driving assembly 33 to connect with the other end of the push rod 362 .
[0048] Continue to see Figure 3 As shown, the plug rod assembly 342 includes a plug rod 3421, a plug rod head 3422 and an elastic member 3423. The plug rod head 3422 is reciprocatably arranged inside the outer tube 341. The plug rod 3421 is connected to the plug rod head 3422. Specifically, the plug rod 3421 is threadedly connected to the plug rod head 3433. The elastic member 3423 is arranged between the plug rod head 3422 and the outer tube 341.
[0049] The plug rod assembly 342 further includes a sealing member 3424 , which is disposed between the plug rod head 3422 and the inner wall of the outer tube 341 .
[0050] In one embodiment, the sealing member 3424 may be an annular sealing ring structure, and the annular sealing ring is disposed between the plug rod head 3422 and the inner wall of the outer tube 341 in a manner of being sleeved on the outer wall of the plug rod head 3422 .
[0051] In some embodiments, the plug rod head 3422 is threadedly connected to the pump head 343, and a sealing structure 3425 is provided at the connection.
[0052] See also Figure 4-Figure 6 As shown, the sample carrying assembly 10 includes a reagent strip support seat 11 and a mounting seat 12, the reagent strip support seat 11 is fixed to the mounting seat 12, and the mounting seat 12 is drivingly connected to the sample delivery assembly 20. The reagent strip support seat 11 is used to mount a reagent strip 100 loaded with a sample and a liquid pipetting head 101.
[0053] In this embodiment, the sample carrying assembly 10 further includes a heating module 13 , which is installed on the reagent strip support seat 11 and is used to heat the reagent strip 100 so that the sample reaches a desired ambient temperature.
[0054] Two heating modules 13 are provided. The two heating modules 13 are respectively arranged on two opposite sides of the reagent strip support seat 11 and are fixed on the reagent strip support seat 11 through a fixing plate 14 .
[0055] The sample-carrying component 10 also includes a fuse 15 , which is connected between the power supply component 50 and the heating module 13 and can cut off the connection between the power supply component 50 and the heating module 13 when the heating temperature of the heating module 13 is too high.
[0056] In order to facilitate the monitoring of the heat generated by the heating module 13, the sample carrying component 10 also includes a temperature sensor 16, which is arranged on the reagent strip support 11 to detect the temperature change of the sample heated by the heating module 13, and when the detected temperature reaches a preset threshold, the power supply component 50 is connected to the heating module 13 through the fuse 15.
[0057] See also Figure 4 As shown, the sample feeding assembly 20 includes a sample feeding drive member 21, a sample feeding screw rod 22 and a sample feeding transmission member 23. The sample feeding drive member 21 is transmission-connected to the sample feeding screw rod 22. The mounting seat 12 is threadedly connected to the sample feeding screw rod 22, and the mounting seat 12 is slidingly connected to the sample feeding transmission member 23. The sample feeding drive member 21 is used to drive the sample feeding screw rod 22 to rotate around its axis. The mounting seat 12 can convert the rotational motion of the sample feeding screw rod 12 into a linear motion along the axis of the sample feeding screw rod 22, and move to a first position and a second position.
[0058] like Figure 6 As shown, two sliding holes 121 and one threaded hole 122 are provided on the mounting seat 12, and the threaded hole 122 is arranged between the two sliding holes 121, wherein one sample feeding screw rod 22 is provided, and the sample feeding transmission member 23 is a rod member, and two are provided, and the sample feeding screw rod 22 is arranged between the two sample feeding transmission members 23, and the two sample feeding transmission members 23 can be slidably passed through the two sliding holes 121, and the sample feeding screw rod 22 is screwed in the threaded hole 122.
[0059] In some embodiments, a linear bearing 123 may be further provided in the sliding hole 121, and the sample feeding transmission member 23 may be slidably provided in the linear bearing 123. In this embodiment, the linear bearing 123 may be limited in the sliding hole 121 by a retaining spring 124.
[0060] In one embodiment, if Figure 6 As shown, a guide sleeve 17 is also provided in the threaded hole 122 to guide the sample feeding screw 22 . In other words, a thread can be provided in the guide sleeve 17 along its axial direction, and the sample feeding screw 22 can be screwed into the threaded hole of the guide sleeve 17 .
[0061] like Figure 1 and Figure 4-Figure 6 As shown, the sample delivery component 20 is further provided with a sample delivery limit sensing unit 24 on the base component 60, and a sensing sheet 18 is further provided on the mounting seat 12. The sample delivery limit sensing unit 24 is electrically connected to the sample delivery driving member 21, and the sample delivery driving member 21 can be controlled to stop working through the induction between the sensing sheet 18 and the sample delivery limit sensing unit 24. The position where the sample delivery limit sensing unit 24 is set is the initial position of the sample carrying component 10, so the initial position where the sample delivery component 20 drives the sample carrying component 10 to reset can be limited.
[0062] See also Figure 7 and Figure 8As shown, the light source assembly 40 includes a light source frame 41, a support frame 42, a light source fixing plate 411 and a light source circuit board 412. A plurality of support columns 421 are provided at the bottom of the support frame 42. The light source frame 41 is installed on the light source fixing plate 411. The light source circuit board 412 is arranged above the light source frame 41. The light source fixing plate 411 is fixed on the support frame 42. The light source circuit board 412 is fixedly connected to the support frame 42.
[0063] In a specific embodiment, the light source circuit board 412 is disposed above the light source frame 41 and fixedly connected to the light source fixing plate 411 , and the light source circuit board 412 is located above the second position.
[0064] In this embodiment, a light source transmitting module and a light source receiving module are provided on the light source circuit board 412. In a preferred embodiment, the light source transmitting module can be a red and blue light source. The light source transmitting module can transmit detection light to the sample and the reagent, and the detection light can be absorbed and reflected by the sample and the reagent, and the light source receiving module receives the reflected light reflected by the sample and the reagent.
[0065] In actual applications, a detection hole is also provided on the reagent strip. When the detection light emitted by the light source transmitting module passes through the detection hole on the reagent strip, it will be absorbed and reflected by the sample and reagent to form reflected light. The reflected light can be received by the light source receiving module. By converting the optical signal of the detection light reflected on the light source receiving module into an electrical signal and converting it, the glycated hemoglobin concentration can be obtained.
[0066] In this embodiment, two light source frames 41 are provided in the light source assembly 40 to meet the dual-channel setting requirement.
[0067] In summary, in the glycated hemoglobin analyzer provided by the present invention, when the sample delivery component drives the sample carrying component to move to the first position, the first drive component drives the connecting component to move toward or away from the first position, so that when the connecting component moves toward the first position, the piercing member can be driven by the connecting component to pierce the film on the reagent strip, and at the same time, the connecting component drives the suction component to move toward the first position to connect the liquid pipette head, and then the second drive component drives the suction component to move back and forth in the first stroke toward or away from the first position, so that the suction component can reciprocate to suck and spit to mix the sample and the reagent. In this way, the sample delivery and detection steps are automated processes, so that fully automated operation can be achieved without human intervention, making the detection process more accurate and efficient.
[0068] The above specific examples are used to illustrate the present invention, which is only used to help understand the present invention and is not intended to limit the present invention. For those skilled in the art, according to the concept of the present invention, some simple deductions, modifications or substitutions can be made.
Claims
1. A glycosylated hemoglobin analyzer, characterized in that: include: At least one sample carrying component, the sample carrying component is used to carry a reagent strip loaded with a sample and a pipette tip; At least one sample delivery component, the sample delivery component is in driving connection with the sample carrying component, and is used to move the sample carrying component to the first position and the second position respectively; At least one plunger pump mechanism, the plunger pump mechanism comprising a first drive assembly, a connecting assembly, a second drive assembly, a suction assembly and a piercing member, the first drive assembly is drivingly connected to the connecting assembly, the second drive assembly is fixed to the connecting assembly, the suction assembly is drivingly connected to the second drive assembly, the piercing member is fixedly installed on the connecting assembly, and the suction assembly faces the liquid-pipette head on the reagent strip in the first position, and the piercing member faces the reagent strip in the first position; The first driving assembly is used to drive the connecting assembly to move toward or away from the first position, so as to drive the piercing member to pierce the film on the reagent strip when moving toward the first position, and connect the suction assembly to the pipette head; the second driving assembly is used to drive the suction assembly to move back and forth toward or away from the first position within the first stroke, so as to enable the suction assembly to suck and discharge reciprocatingly; At least one light source assembly is disposed above the second position and is used to emit a detection light source to the sample for detection.
2. The glycated hemoglobin analyzer according to claim 1, characterized in that: The plunger pump mechanism also includes a liquid withdrawal head assembly, which is movably connected to the suction assembly and is transmission-connected to the second drive assembly. The second drive assembly is also used to drive the liquid withdrawal head assembly to move toward or away from the first position within a second stroke to push against the liquid suction head and disengage from the suction assembly; the length of the second stroke is greater than the length of the first stroke.
3. The glycated hemoglobin analyzer according to claim 2, characterized in that: The suction assembly comprises an outer cylinder, a plug rod assembly and a pump head, wherein the outer cylinder is fixed to the connecting assembly, the plug rod assembly is reciprocatably arranged inside the outer cylinder and connected to the second driving assembly, the pump head is connected to the plug rod assembly, and a cavity is arranged inside the pump head; the pump head can cover the liquid suction head when moving toward the liquid suction head in the first position; the second driving assembly drives the plug rod assembly to reciprocate along the axial direction of the outer cylinder, so that negative pressure is generated in the cavity; The liquid withdrawal head assembly is movably connected to the pump head.
4. The glycated hemoglobin analyzer according to claim 3, characterized in that: The liquid withdrawal head assembly includes a push cylinder and a push rod. The push cylinder is sleeved on the outside of the pump head and connected to one end of the push rod. The other end of the push rod is connected to the second driving assembly.
5. The glycated hemoglobin analyzer according to claim 3, characterized in that: The plug rod assembly comprises a plug rod, a plug rod head and an elastic member. The plug rod head is reciprocatably arranged inside the outer tube. The plug rod is connected to the plug rod head. The elastic member is arranged between the plug rod head and the outer tube.
6. The glycated hemoglobin analyzer according to claim 5, characterized in that: The plug rod assembly further comprises a sealing member, which is arranged between the plug rod head and the inner wall of the outer tube.
7. The glycated hemoglobin analyzer according to claim 1, characterized in that: The sample carrying assembly includes a reagent strip support seat and a mounting seat, wherein the reagent strip support seat is fixed to the mounting seat, and the mounting seat is transmission-connected to the sample delivery assembly; the reagent strip support seat is used to mount a reagent strip loaded with a sample and a pipette head.
8. The glycated hemoglobin analyzer according to claim 7, characterized in that: The sample carrying assembly also includes a heating module, which is installed on the reagent strip support seat and is used to heat the reagent strip.
9. The glycated hemoglobin analyzer according to claim 1, characterized in that: The sample delivery component includes a sample delivery drive, a sample delivery screw and a sample delivery transmission component. The sample delivery drive is transmission-connected to the sample delivery screw, the mounting seat is threadedly connected to the sample delivery screw, and the mounting seat is slidingly connected to the sample delivery transmission component. The sample delivery drive is used to drive the sample delivery screw to rotate around its axis, and the mounting seat can convert the rotational motion of the sample delivery screw into a linear motion along the axis of the sample delivery screw, and move to the first position and the second position.
10. The glycated hemoglobin analyzer according to claim 1, characterized in that: The light source assembly includes a light source frame, a support frame, a light source fixing plate and a light source circuit board, wherein the light source fixing plate is fixed on the support frame, the light source circuit board is connected to the support frame, the light source circuit board is arranged above the light source frame and fixedly connected to the light source fixing plate, and the light source circuit board is located above the second position; the light source circuit board is provided with a light source transmitting module and a light source receiving module, the light source transmitting module is used to transmit detection light to the sample and reagent in the reagent strip, and the light source receiving module is used to receive reflected light reflected by the sample and reagent.