External traditional Chinese medicine composition for treating fracture and rheumatalgia and application thereof

Abstract

The invention provides an external traditional Chinese medicine composition for treating fracture and rheumatalgia and application thereof, and belongs to the technical field of traditional Chinese medicines. The external traditional Chinese medicine composition is prepared from the following raw materials: herba lycopodii, rhizoma drynariae, spiny amaranth herb, radix clematidis, herba portulacae, elephantopus scaber, cherokee rose root, suberect spatholobus stem, tendril-leaved crabapple root, bock greenbrier rhizome, rhizoma anemarrhenae, graceful jessamine herb, herba asari, cinnamomum camphora, wormwood, radix et rhizoma rhei, dragon's blood and rhizoma zingiberis. The medicinal materials are matched with one another, so that the traditional Chinese medicine has the effects of tonifying qi and stopping bleeding, removing blood stasis and promoting tissue regeneration, eliminating blood stasis and relieving pain, setting bones and promoting reunion as well as opening orifices and activating blood, has the main effect of dispelling wind-cold-wetness evil, and can be used for relieving swelling and pain, drawing out poison and promoting tissue regeneration as well as setting bones and promoting reunion. The composition has a remarkable curative effect on external treatment of internal diseases, injury of tendons and bones, hyperplasia and rheumatism numbness.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to an external Chinese medicine composition for treating bone fractures and rheumatic pain and application thereof. Background Art

[0002] Fracture refers to the interruption of the continuity of bones and trabeculae, and the destruction of the integrity of bones. The external cause of fracture is external force injury. Traditional Chinese medicine has known about fractures for a long time. The "Silk Book of Medicine" in the Han Dynasty recorded "broken bones and severed tendons" and "broken bones and cracked skin". There are many ways to treat fractures, and once the fracture is fixed, it is particularly important to use medicine based on syndrome differentiation. Summary of the invention

[0003] The purpose of the present invention is to provide an external Chinese medicine composition for treating bone fractures and rheumatic pain and its application. The external Chinese medicine composition of the present invention has good bone setting and blood stasis removing effects and can effectively treat bone fractures and rheumatic pain.

[0004] The invention provides a traditional Chinese medicine composition for external use for treating bone fracture and rheumatic pain. The composition comprises the following raw materials in parts by weight: 130-170 parts of smilax china, 130-170 parts of drynaria rhizome, 130-170 parts of spiny amaranth, 130-170 parts of clematis, 130-170 parts of purslane, 130-170 parts of scutellaria baicalensis, 130-170 parts of golden cherry root, 130-170 parts of millettia reticulata, 130-170 parts of scutellaria baicalensis, 130-170 parts of scutellaria baicalensis, 130-170 parts of golden cherry root, 130-170 parts of millettia reticulata, 130-170 parts of scutellaria baicalensis, 30-70 parts of aconite, 30-70 parts of asarum, 130-170 parts of camphor tree, 130-170 parts of wormwood, 30-70 parts of rhubarb, 30-70 parts of dragon's blood and 130-170 parts of dried ginger.

[0005] Preferably, the raw materials include the following in parts by weight: 150 parts of lycopodii herb, 150 parts of drynaria rhizome, 150 parts of amaranth, 150 parts of clematis, 150 parts of purslane, 150 parts of scutellaria baicalensis, 150 parts of golden cherry root, 150 parts of millettia reticulata, 150 parts of scutellaria baicalensis, 150 parts of golden hollyhock root, 150 parts of rhubarb, 150 parts of scutellaria baicalensis, 150 parts of golden hollyhock root, 150 parts of yellow dog head, 50 parts of aconite, 50 parts of asarum, 150 parts of camphor tree, 150 parts of wormwood, 150 parts of pine wood, 50 parts of rhubarb, 50 parts of blood clotting and 150 parts of dried ginger.

[0006] The present invention also provides an external ointment for treating bone fractures and rheumatic pain, comprising the external Chinese medicine composition and auxiliary materials described in the above scheme.

[0007] Preferably, the auxiliary materials include starch, brown sugar, honey, tea oil or sesame oil.

[0008] Preferably, the auxiliary materials are composed of starch, brown sugar, honey and tea oil; the mass fraction of starch in the external ointment is 2%; the mass fraction of brown sugar in the external ointment is 3%; the mass fraction of honey in the external ointment is 5%; and the mass fraction of tea oil in the external ointment is 10%.

[0009] The present invention also provides a method for preparing the external ointment described in the above scheme, comprising the following steps:

[0010] Taking each raw medicinal material of the external Chinese medicine composition, crushing them and passing them through a 100-mesh sieve, and collecting the fine powder under the sieve;

[0011] The fine powder is mixed with water, and soaked and boiled for the first time in sequence;

[0012] After the first decoction, adding water for a second decoction;

[0013] After the second decoction, adding auxiliary materials for boiling to obtain an external ointment;

[0014] In the first decoction process, firstly heat to boil over high heat, and then continue to decoct over low heat for 20 to 30 minutes;

[0015] In the second decoction process, the mixture is first boiled and then simmered over low heat for 20 minutes.

[0016] Preferably, the soaking time is ≥30 min.

[0017] The present invention also provides the use of the external Chinese medicine composition described in the above scheme, the external ointment or the external ointment prepared by the preparation method in the preparation of a medicine for treating any of the following diseases: bone fracture, bone fracture, bone sprain, bone displacement, traumatic injury, bone hyperplasia, rheumatic numbness and joint pain.

[0018] Preferably, the fracture includes a new closed fracture or an old closed fracture.

[0019] The present invention also provides the use of the external Chinese medicine composition described in the above scheme, the external ointment or the external ointment prepared by the preparation method in preparing a medicine with any one of the following effects: replenishing qi and stopping bleeding, removing blood stasis and promoting new blood, and removing blood stasis and relieving pain.

[0020] The invention provides a Chinese medicine composition for external use for treating bone fracture and rheumatic pain, comprising the following raw materials: spatholobi, rhizoma drynariae, amaranth, clematis, purslane, scutellaria, root of golden cherry, spatholobi, datongjin, jingangteng, yam, herba scutellariae, asarum, camphor tree, wormwood, rhubarb, blood clotting and dried ginger. The Chinese medicine composition for external use of the invention has the effects of replenishing qi and stopping bleeding, removing blood stasis and promoting new blood, removing blood stasis and relieving pain, setting bones and tendons, and opening the orifices and activating blood circulation, mainly removing wind, cold and dampness, and can be used for reducing swelling and relieving pain, removing toxins and promoting muscle growth, setting bones and tendons, and has significant curative effects on external treatment of internal diseases, broken tendons and bones, hyperplasia and rheumatism and numbness. The external Chinese medicine composition of the present invention can be prepared into an external ointment and directly applied to the acupuncture points on the body surface. The medicinal properties penetrate the skin and pores from the surface to the inside and penetrate into the subcutaneous tissue. On the one hand, a relative advantage of drug concentration is produced locally; on the other hand, it can directly reach the diseased area of ​​visceral and meridian disorders through the penetration of meridians, exerting drug and functional effects, thereby exerting the maximum systemic pharmacological effect. The external Chinese medicine composition of the present invention can directly act on the affected area, increase the drug efficacy several times, and is not easy to produce drug resistance. DETAILED DESCRIPTION

[0021] The present invention provides a Chinese medicine composition for external use for treating bone fracture and rheumatic pain, comprising the following raw materials in parts by weight:

[0022] 130-170 parts of Herba Lycopodii, 130-170 parts of Rhizoma Drynariae, 130-170 parts of Herba Amaranthus spinulosae, 130-170 parts of Radix Clematis, 130-170 parts of Herba Portulacae, 130-170 parts of Herba Echinops, 130-170 parts of Radix Chrysanthemi Indici, 130-170 parts of Caulis Spatholobi, 130-170 parts of Radix Datongjin, 130-170 parts of Radix Angelicae Pubescentis, 130-170 parts of Radix Gnaphalii, 30-70 parts of Herba Gnaphalii, 30-70 parts of Asarum, 130-170 parts of Cinnamomum camphora, 130-170 parts of Herba Artemisiae Argyi, 30-70 parts of Radix Rhei, 30-70 parts of Sanguisorba Officinalis and 130-170 parts of Drynariae Zingiberensis.

[0023] In the specific implementation of the present invention, the external Chinese medicine composition is preferably composed of the following raw materials in parts by weight: 130-170 parts of Lycopodiella Ceratoniae, 130-170 parts of Drynariae Rhizoma, 130-170 parts of Amaranthus spinulosae, 130-170 parts of Clematis chinensis, 130-170 parts of Portulaca oleracea, 130-170 parts of Euphorbia pulcherrima, 130-170 parts of Millettia reticulata, 130-170 parts of Datongjin, 130-170 parts of Vulgaris chinensis, 130-170 parts of Rhizoma Cynomorii, 30-70 parts of Gnaphalium wilfordii, 30-70 parts of Asarum, 130-170 parts of Cinnamomum camphora, 130-170 parts of Artemisia argyi, 30-70 parts of Rhubarb, 30-70 parts of Sanguisorba officinalis and 130-170 parts of dried ginger.

[0024] In the specific implementation process of the present invention, the external Chinese medicine composition includes the following raw materials in parts by weight: 150 parts of lycopodii herb, 150 parts of drynaria, 150 parts of amaranth, 150 parts of clematis, 150 parts of purslane, 150 parts of scutellaria baicalensis, 150 parts of golden cherry root, 150 parts of millettia reticulata, 150 parts of scutellaria baicalensis, 150 parts of golden hollyhock root, 150 parts of spatholobus, 150 parts of scutellaria baicalensis, 150 parts of golden hollyhock root, 150 parts of coleus, 50 parts of aconite, 50 parts of asarum, 150 parts of camphor tree, 150 parts of wormwood, 50 parts of rhubarb, 50 parts of blood clotting and 150 parts of dried ginger.

[0025] In one embodiment of the present invention, the external Chinese medicine composition is composed of the following raw materials in parts by weight: 150 parts of lycopodii herb, 150 parts of drynaria rhizome, 150 parts of amaranth, 150 parts of clematis, 150 parts of purslane, 150 parts of scutellaria baicalensis, 150 parts of golden cherry root, 150 parts of millettia reticulata, 150 parts of scutellaria baicalensis, 150 parts of golden hollyhock root, 150 parts of spatholobi, 150 parts of giant hyssop, 150 parts of golden hollyhock root, 50 parts of aconite, 50 parts of asarum, 150 parts of camphor tree, 150 parts of wormwood, 50 parts of rhubarb, 50 parts of blood clotting and 150 parts of dried ginger.

[0026] The Chinese medicine composition of the present invention is composed of two echelons of drugs, the first echelon treats bone fractures or fractures. The other echelon replenishes qi and stops bleeding, removes blood stasis and promotes new growth, and eliminates blood stasis and relieves pain. The two echelons are combined together to complete the composition. In the first echelon, Drynariae, Asarum, Sanguisorba officinalis, Goldenseal, Clematis, Rhubarb, Datongjin and Spatholobus chinensis work together to treat bone fractures or fractures caused by falls and to open the orifices and activate blood circulation. The herb is made up of Drynaria as the main drug, and Asarum, Blood Jelly, Goldenrod, Clematis, Rhubarb, Datongjin, and Stretchjincao as the secondary drugs; among them, Drynaria is warm in nature, bitter in taste, and enters the liver and kidney meridians, and has the effects of tonifying the kidney and strengthening bones, dispersing blood stasis and relieving pain, and strengthening tendons; Goldenrod has the effects of promoting blood circulation and chemotherapy, dispelling wind and dampness, relieving swelling and relieving pain and detoxification; Asarum has the effects of dispelling wind and opening the orifices to relieve pain; Blood Jelly has the effects of removing blood stasis, relieving pain and stopping bleeding and promoting tissue regeneration; Clematis is good at moving and not staying, and can run throughout the body to dredge blood stasis and promote blood circulation; Rhubarb has the effects of cooling blood and detoxifying, removing blood stasis and dredge meridians, and has the effects of treating blood stasis caused by falls; Datongjin and Stretchjincao are It has the effects and functions of relaxing muscles and tendons, dispelling wind and dampness, relieving pain, relieving spasms and reducing swelling; Da Shenjin has the effects of relaxing muscles and tendons, promoting blood circulation and strengthening muscles. It also has a certain effect of dispelling wind, and eliminates wind evil in the body by regulating the circulation of qi and blood. At the same time, it can also promote excretion in the body, relieve pain symptoms, and has the effect of relaxing smooth muscles, so it can have a certain antispasmodic effect; Shenjincao and Da Shenjin both have the effect of reducing swelling and promoting local blood circulation, which helps to reduce tissue edema and inflammatory response, thereby achieving the purpose of reducing swelling, and they are combined to promote the healing of bone fractures or fractures.

[0027] In the second echelon, yellow dog head, prickly amaranth, purslane, ground dandelion, golden cherry root, Millettia reticulata, Gelsemium elegans, camphor tree, wormwood and dried ginger work together to treat the effects of replenishing qi and stopping bleeding, removing blood stasis and promoting new growth, and removing blood stasis and relieving pain. Yellow dog head is the main medicine, and prickly amaranth, purslane, ground dandelion, golden cherry root, Millettia reticulata, Gelsemium elegans, camphor tree, wormwood and dried ginger are the assistant and adjuvant medicines. Yellow dog head is the main medicine, which has the effects of removing swelling and dampness, promoting blood circulation and removing blood stasis; Millettia reticulata has the effects of replenishing blood, promoting blood circulation and unblocking meridians; Golden cherry root has the effects of promoting blood circulation and removing blood stasis, clearing away heat and detoxifying, and reducing inflammation and sterilization, which can accelerate local blood circulation and metabolism, and can dilate blood vessels to make local blood circulation smoother; Golden cherry root and Millettia reticulata are the assistants, which can promote local blood stasis removal and regeneration, and accelerate tendon and bone repair; Gelsemium elegans tastes pungent and bitter, is warm in nature, and is highly toxic, and has the effects of attacking and removing toxins, dispersing It has the effects of relieving blood stasis and relieving pain, killing insects and relieving itching; the herb has the effects of clearing away heat and detoxifying, reducing swelling and relieving pain; Amaranthus spinulosa and Purslane are hemostatics with the effects of cooling blood and relieving pain, detoxifying and reducing swelling; Cinnamomum camphora has the effects of dispersing, reducing swelling and relieving pain; Mugwort has the effects of relieving pain, anti-inflammatory, warming the meridians and stopping bleeding, removing dampness and relieving itching; dried ginger has the effects of anti-inflammatory and antibacterial, analgesic, antioxidant, promoting circulation, etc. and can relieve symptoms such as fever and pain. Dried ginger harmonizes various medicines and serves as a guiding medicine.

[0028] In the specific implementation process of the present invention, Herba Lycopodii, Rhizoma Drynariae, Amaranthus spinulosus, Radix Clematis, Herba Portulacae, Herba Lycopodii, Radix Chrysanthemi, Caulis Spatholobi, Radix Datongjin, Caulis Venetianis, Herba Gnaphalii, Herba Gnaphalii, Asarum, Cinnamomum camphora, Artemisia argyi, Radix Rhei, Dracaenae and Rhizoma Zingiberis are used together, which has the effects of reducing swelling and relieving pain, removing toxins and promoting tissue regeneration, connecting bones and tendons, and has significant curative effect on external treatment of internal diseases, treating injured tendons and broken bones, hyperplasia and rheumatism and numbness. Looking at the whole prescription, the external Chinese medicine composition of the present invention is mainly based on promoting the healing of bone fractures or fractures and rheumatic pain, supplemented by products for promoting blood circulation, removing blood stasis and benefiting qi and blood, taking into account both the evil and the righteous, removing evil without hurting the righteous, strengthening the righteous without leaving evil, unique compatibility, external treatment of internal diseases, and significant clinical curative effect.

[0029] The present invention also provides an external ointment for treating bone fractures and rheumatic pain, comprising the external Chinese medicine composition and auxiliary materials described in the above scheme.

[0030] In the specific implementation process of the present invention, the external ointment includes an ointment or a plaster; the ointment can be directly applied to the affected area; the plaster is made into a traditional Chinese medicine patch and applied to the affected area.

[0031] In the specific implementation process of the present invention, the external ointment is named Fengyuan Huayu Ointment.

[0032] In the specific implementation of the present invention, the auxiliary material includes starch, brown sugar, honey, tea oil or sesame oil. In the specific implementation of the present invention, the auxiliary material is used to increase the consistency and efficacy of the external ointment.

[0033] In one embodiment of the present invention, the auxiliary materials are composed of starch, brown sugar, honey and tea oil; the mass fraction of starch in the external ointment is 2%; the mass fraction of brown sugar in the external ointment is 3%; the mass fraction of honey in the external ointment is 5%; and the mass fraction of tea oil in the external ointment is 10%.

[0034] The present invention also provides a method for preparing the external ointment described in the above scheme, comprising the following steps:

[0035] Taking each raw medicinal material of the external Chinese medicine composition, crushing them and passing them through a 100-mesh sieve, and collecting the fine powder under the sieve;

[0036] The fine powder is mixed with water, and soaked and boiled for the first time in sequence;

[0037] After the first decoction, adding water for a second decoction;

[0038] After the second decoction, adding auxiliary materials for boiling to obtain an external ointment;

[0039] In the first decoction process, firstly heat to boil over high heat, and then continue to decoct over low heat for 20 to 30 minutes;

[0040] In the second decoction process, the mixture is first boiled and then simmered over low heat for 20 minutes.

[0041] The present invention first takes each raw medicinal material of the external Chinese medicine composition, crushes it, passes it through a 100-mesh sieve, and collects the fine powder under the sieve. Before the crushing, the present invention also includes steaming and roasting each raw medicinal material of the external Chinese medicine composition. In the specific implementation process of the present invention, the crushing includes crushing with a crusher; the aperture of the sieve used for the sieving is 100 mesh.

[0042] After collecting the fine powder under the sieve, the present invention mixes the fine powder with water, and performs soaking and first decoction in sequence. In the specific implementation process of the present invention, the soaking time is ≥30min; the water is cold water; the water added in the first decoction is 3-5cm higher than the medicine surface to ensure that the water volume is sufficient to cover the medicine; in the first decoction process, it is first heated to boil with high heat, and then continued to be decocted with low heat for 20-30min, wherein low heat means that the water is slowly heated to the boiling temperature; high heat means that the water is quickly heated to the boiling temperature. In the specific implementation process of the present invention, the high heat is heated to 200℃ in the first decoction process.

[0043] After the first decoction, the present invention adds water for a second decoction; the water added for the second decoction is 3 to 5 cm higher than the medicine surface to ensure that the water volume is sufficient to cover the medicine; during the second decoction, the medicine is first boiled and then decocted over low heat for 20 minutes; the boiling temperature is 100°C.

[0044] After the second decoction, the present invention adds auxiliary materials for boiling to obtain an external ointment. Stirring is accompanied during the boiling process. After boiling for a period of time, the external ointment will gradually become thick. At this time, the heat can be reduced and boiling can be continued for a period of time until the desired consistency is reached. At the same time, the liquid medicine is continuously stirred to prevent coking and gradually form a thick paste.

[0045] After boiling, the present invention further comprises cooling the boiled concentrated external ointment to 40°C, and spreading the external ointment on a backing material to obtain a Chinese medicine patch; the backing material comprises dried leather, cloth or paper; the mass of the external ointment of each Chinese medicine patch is 5g, 9g or 15g.

[0046] In the specific implementation process of the present invention, the containers used for the first decoction, the second decoction and the boiling are casseroles, pottery pots or ceramic pots.

[0047] In the specific implementation process of the present invention, the method for using the external ointment comprises the following steps:

[0048] The external ointment is applied to the affected area and bandaged; or the external ointment is made into a Chinese medicine patch and applied to the affected area. The frequency of dressing change is once a day.

[0049] The present invention also provides the use of the external Chinese medicine composition described in the above scheme, the external ointment, the external ointment prepared by the preparation method or the Chinese medicine patch in the preparation of a medicine for treating any of the following diseases: bone fracture, bone fracture, bone sprain, bone displacement, traumatic injury, bone hyperplasia, rheumatic numbness and joint pain.

[0050] In the specific implementation of the present invention, the fracture includes a new closed fracture or an old closed fracture.

[0051] The present invention also provides the use of the external Chinese medicine composition described in the above scheme, the external ointment, the external ointment prepared by the preparation method or the Chinese medicine patch in the preparation of a medicine with any of the following effects: replenishing qi and stopping bleeding, removing blood stasis and promoting new blood, and removing blood stasis and relieving pain.

[0052] To further illustrate the present invention, an external Chinese medicine composition for treating bone fractures and rheumatic pain and its application provided by the present invention are described in detail below in conjunction with examples, but they should not be construed as limiting the scope of protection of the present invention.

[0053] Example 1

[0054] External ointment: It is composed of external Chinese medicine composition and excipients.

[0055] The composition of the external Chinese medicine composition is as follows:

[0056] 150g of Herba Lycopodii, 150g of Rhizoma Drynariae, 150g of Herba Amaranthus spinulosae, 150g of Radix Clematis, 150g of Herba Portulacae, 150g of Herba Lycopodii, 150g of Radix Achyranthis Bidentatae, 150g of Radix Spatholobi, 150g of Herba Spatholobi, 150g of Herba Cynanchifoliae, 150g of Herba Cynanchi, 150g of Herba Gnaphalii, 50g of Herba Asarum, 150g of Herba Cinnamomi, 150g of Herba Artemisiae Argyi, 50g of Herba Rhei, 50g of Herba Sanguisorbae and 150g of Dried Ginger; the raw materials of the external Chinese medicine composition are crushed into fine powder by a grinder and passed through a 100-mesh sieve.

[0057] Excipients: composed of starch, brown sugar, honey and tea oil; the mass fraction of starch in the external ointment is 2%; the mass fraction of brown sugar in the external ointment is 3%; the mass fraction of honey in the external ointment is 5%; the mass fraction of tea oil in the external ointment is 10%.

[0058] Preparation method:

[0059] Mix the fine powder of the Chinese medicine composition with water, soak for 30 minutes, and then decoct twice in sequence. During the first decoction, add enough water to be 3 to 5 cm above the medicine surface. First boil it with high heat to 200°C, and then continue to simmer for 20 to 30 minutes. During the second decoction, add water about 3 cm above the medicine surface. After the water boils to 100°C, continue to simmer for 20 minutes, then add starch, brown sugar, honey and tea oil, and stir continuously. After a period of boiling, the external ointment will gradually become thick. At this time, the heat can be reduced and the boiling can be continued for a period of time until the desired consistency is reached. At the same time, the liquid medicine is stirred continuously with chopsticks or bamboo flats to prevent coking, and gradually a thick paste is formed. Cool to 40°C to obtain an external ointment named Fengyuan Huayu Paste. During treatment, the external ointment is melted, evenly spread on the external ointment cloth, and applied to the affected area or painful area. The dressing is changed once a day.

[0060] Example 2

[0061] The composition of the external Chinese medicine composition is as follows:

[0062] 130g of Stretch Muscle Grass, 130g of Drynaria, 130g of Amaranthus pricklyris, 130g of Clematis, 130g of Portulaca Oleracea, 130g of Herba Lycopodii, 130g of Radix Angelicae Pubescentis, 130g of Millettia Reticulata, 130g of Datongjin, 130g of Vajra Vulgaris, 130g of Codonopsis pilosula, 30g of Gnaphalium, 30g of Asarum, 130g of Cinnamomum camphora, 130g of Mugwort, 30g of Rhubarb, 30g of Sanguisorba Officinalis and 130g of Dried Ginger.

[0063] The preparation method is the same as Example 1.

[0064] Example 3

[0065] The composition of the external Chinese medicine composition is as follows:

[0066] 170g of Stretch Muscle Grass, 170g of Drynaria, 170g of Amaranthus pricklyris, 170g of Clematis, 170g of Portulaca Oleracea, 170g of Herba Lycopodii, 170g of Radix Chrysanthemi Indici, 170g of Millettia Spatholobi, 170g of Datongjin, 170g of Vajra Vulgaris, 170g of Codonopsis pilosula, 70g of Gastrodia elata, 70g of Asarum, 170g of Cinnamomum camphora, 170g of Mugwort, 70g of Rhubarb, 70g of Sanguisorba officinalis and 170g of dried ginger.

[0067] The preparation method is the same as Example 1.

[0068] Clinical Trial 1

[0069] From 1985 to date, 200 patients who also used the external plaster of the present invention, Fengyuan Huayu Paste, were selected from patients with traumatic injuries, bone fractures, fractures, rheumatism, rheumatoid arthritis, and muscular rheumatic pain in the Department of Orthopedics and were divided into two groups. One group of 100 patients with fractures were treated, and the symptom time was divided into 10 days, 20 days, and 200 days after the fracture, and the external plaster prepared in Example 1, Fengyuan Huayu Paste, was used. Another group of 100 patients with rheumatic pain were treated, and the symptom time of the embodiment was within 1 year, 2 years, and more than 5 years, and the external plaster prepared in Example 1, Fengyuan Huayu Paste, was used.

[0070] The two groups of patients were statistically analyzed in terms of condition and course of disease, and there was no significant difference, so they were comparable.

[0071] Criteria for judging the efficacy of external plasters:

[0072] Cured: All symptoms disappear, functional activities return to normal, and major Western medical physical and chemical indexes are normal;

[0073] Markedly effective: All symptoms or major symptoms are eliminated, joint function is basically restored, the patient can participate in normal work and labor, and major physical and chemical indicators of Western medicine are basically normal;

[0074] Effective: The main symptoms are basically eliminated, the functions of the main joints are basically restored or have improved significantly, and the main physical and chemical indicators of Western medicine have improved;

[0075] Ineffective: Compared with before treatment, there is no improvement in all aspects.

[0076] The test results are shown in Table 1.

[0077] Table 1 Clinical trial results of topical plaster

[0078]

[0079] As can be seen from Table 1, the medicine is effective for patients with general fractures and rheumatism after 10 days of use, and for patients with severe conditions after 30 days of use. The cure rate after two months of use is 96 percent.

[0080] Case 1

[0081] A 2-week-old child accidentally fell from the bed, landing on his palm and shoulder. The force was transmitted to the clavicle, causing a transverse fracture and dislocation. He felt obvious pain when moving, and cried whenever he moved. X-rays taken at the hospital revealed fractures and dislocation.

[0082] Treatment plan: First, restore the affected area, then apply the Fengyuan Huayu ointment prepared in Example 1 to the affected area, and fix and bandage it for protection. Change the dressing the next day after applying the ointment, the fractured bone is no longer displaced, and the hand can move. Apply Fengyuan Huayu ointment for another two days, and there is no redness, swelling, skin lesions or infection after unbandaging, and the hand can move freely, and is basically cured. Consolidate the bandage for another day, and it is completely cured.

[0083] Case 2

[0084] Li, male, 30 years old, fell down accidentally and then developed swelling all over his body. He went to the hospital for an X-ray and was diagnosed with a compression fracture of the 12th thoracic vertebra. He was still unable to get up after a month of hospitalization and his condition did not improve. Since the patient did not want to undergo surgery, he decided to go home to recuperate and believed in traditional Chinese medicine, so he chose conservative treatment.

[0085] Treatment plan: Oral administration and external application of Fengyuan Huayu ointment prepared in Example 1 were performed to treat both internal and external factors. After bandaging on the second day, the patient felt pain relief, could get up and sit, gradually recovered and felt relaxed. One week later, the effect of the patient's dressing and bandaging was significant, the pain was significantly relieved, and he could walk and walk, and his confidence was greatly increased. The bandaging treatment was continued every two days, and the pain completely disappeared after one month, and he could walk on his own.

[0086] Case 3

[0087] Ms. Zhang is nearly 50 years old. When she was in her twenties, she was hit by a car on the right shoulder blade of her back. She was unable to speak for a long time. Although she tried some treatments, there was no improvement. For more than 20 years, she often felt pain in the injured back, especially when the weather changed. The pain affected the surrounding meridians and radiated to other parts of the body. It was difficult to heal over time.

[0088] Treatment plan: After syndrome differentiation, observe the skin of the affected area first, apply medicated wine on the affected area, gently apply the skin, find the pain point, increase the strength appropriately, push and press along the meridians, and after determining the range of the pain point, apply the Fengyuan Huayu Paste prepared in Example 1 to the painful area. With the help of the dispersing and penetrating power of Fengyuan Huayu Paste, it can promote blood circulation in the injured area, reduce swelling and relieve pain, and effectively promote the healing of old injuries. After a week, the patient gradually recovered and felt very happy. Continue to apply the affected area once every two days, combined with oral Chinese herbal medicine, and the effect is remarkable after one month, and it is basically cured.

[0089] Case 4

[0090] Ms. Zhang, 23 years old, was hit by a car and injured her left upper arm. At that time, the skin was lacerated, bleeding and accompanied by severe pain, and upper limb dysfunction. She went to the local hospital for an emergency examination and found a fracture, with a large amount of soil, sand and small gravel in the wound. Debridement and suture were immediately performed, necrotic tissue was removed, and the fracture ends were aligned. A four-hole steel plate was used for internal fixation, and the broken muscles and soft tissues were sutured. After the operation, the affected limb was fixed with plaster, and the stitches were removed on schedule. She was discharged from the hospital after the wound healed in the first stage. Three months later, an outpatient review found that the fracture end still had abnormal activity, and the X-ray showed no callus formation, so plaster fixation continued. One month later, the patient requested treatment with traditional Chinese medicine. When she came to the hospital for examination, it was found that the muscles of the left upper arm were atrophied, the fracture end still had abnormal activity, and the arm could not be raised. The X-ray showed that the fracture end was partially absorbed and slightly hardened, with a gap of about 0.3 cm, and a small amount of callus on the dorsal side, but it did not cross the fracture line. The diagnosis was nonunion.

[0091] Treatment plan: Give the external application of Fengyuan Huayu ointment prepared in Example 1, apply it once every two days, and use a small splint for local external fixation, and cooperate with shoulder, elbow, and finger functional exercises. After one month of continuous external application treatment, the fracture gap is reduced, more callus is formed at the fracture end, and the activity is not obvious. Use Fengyuan Huayu ointment for external application and bandage treatment for one month, and the film shows that a large amount of callus is formed, and the function of the affected limb is basically restored.

[0092] Case 5

[0093] The patient, Mr. Li, is a 30-year-old male. He fell to the ground after hitting his left calf while riding an electric bike. At that time, his left calf was bleeding and the bone was exposed, so he went to the local hospital for emergency treatment. The emergency doctor immediately performed debridement and performed a four-hole steel plate internal fixation on the tibial fracture. Wound infection occurred after the operation. After treatment, the wound healed and the affected limb was fixed with a plaster splint. After two months of treatment, the fracture end still did not heal. The patient then requested Chinese medicine treatment. When he came to the clinic, the physical examination revealed: tenderness in the middle of the left calf, an angle of about 20 degrees forward, abnormal activity at the fracture end, accompanied by pain, and calf muscle atrophy of about 3cm. Although the affected limb can be raised, it cannot bear weight. X-rays showed: transverse fracture of the middle part of the left tibia, good anteroposterior alignment, an angle of about 20 degrees forward in the lateral position, and a gap of about 0.2cm between the fracture ends. It is not suitable for further surgery.

[0094] Treatment plan: Use the Fengyuan Huayu ointment prepared in Example 1 to apply to the affected area to correct the deformity, then use a small splint for local external fixation, and advise the patient to strengthen functional exercise. Use Fengyuan Huayu ointment once every two days and apply it to the affected area. After ten days, the patient can get out of bed and move around, and the affected limb can bear weight appropriately. After one month of external application treatment, the patient got out of bed and moved well, with no local pain and no abnormal activity. X-rays showed that the fracture angle had been corrected and callus had formed at the fracture end. After another month of dressing consolidation, the reexamination results showed that he was basically cured.

[0095] Case 6

[0096] Li, male, 40 years old, shoulder pain, no joint deformation, pain for more than one year, aggravated by wind and cold. Use Fengyuan Huayu Paste prepared in Example 1 for external application, once every 2 days, after two weeks of use, the pain is significantly relieved, the main joint function is basically restored; after 30 days, the pain is completely relieved, the joint function returns to normal, and the patient is basically cured.

[0097] Case 7

[0098] Zhang, male, 50 years old, suffers from rheumatoid arthritis. He had hip joint swelling and pain for two years, stiff legs, and the pain worsened when he sat for a long time or caught a cold. He used Fengyuan Huayu Ointment and applied the Fengyuan Huayu Ointment prepared in Example 1 to the painful area once every 2 days. After 20 days of use, the pain was significantly relieved. After 60 days of continued use, the pain basically disappeared, and there was no pain after sitting for a long time. After 3 months, the pain completely disappeared, and he was cured after a follow-up visit 1 year later.

[0099] Case 8

[0100] Huang, female, 55 years old, has swollen and painful joints in her hands and feet, deformed joints, and thigh muscle atrophy. She has had rheumatism for more than ten years. She has stiff hands and feet after getting up in the morning, difficulty walking, swollen legs, and long-term use of anti-inflammatory and analgesic drugs. Her condition is sometimes good and sometimes bad during medication. She then used the Fengyuan Huayu Paste prepared in Example 1 once every two days on the painful points. After 20 days, the pain was relieved, and after 60 days, the pain was completely relieved. After half a year, the joints of her hands and feet returned to normal, and all indicators were normal when she went to the hospital for examination.

[0101] Although the above embodiment describes the present invention in detail, it is only a part of the embodiments of the present invention, not all of them. People can obtain other embodiments based on this embodiment without creative work, and these embodiments all belong to the protection scope of the present invention.

Claims

1. A Chinese medicine composition for external use for treating bone fractures and rheumatic pain, characterized in that: The invention comprises the following raw materials in parts by weight: 130-170 parts of Herba Lycopodii, 130-170 parts of Rhizoma Drynariae, 130-170 parts of Herba Amaranthus spinulosae, 130-170 parts of Radix Clematis, 130-170 parts of Herba Portulacae, 130-170 parts of Herba Echinops, 130-170 parts of Radix Chrysanthemi Indici, 130-170 parts of Caulis Spatholobi, 130-170 parts of Radix Datongjin, 130-170 parts of Radix Angelicae Pubescentis, 130-170 parts of Radix Gnaphalii, 30-70 parts of Herba Gnaphalii, 30-70 parts of Asarum, 130-170 parts of Cinnamomum camphora, 130-170 parts of Herba Artemisiae Argyi, 30-70 parts of Radix Rhei, 30-70 parts of Sanguisorba Officinalis and 130-170 parts of Drynariae Zingiberensis.

2. The external Chinese medicine composition according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 150 parts of Herba Lycopodii, 150 parts of Rhizoma Drynariae, 150 parts of Herba Amaranthus spinulosae, 150 parts of Radix Clematis, 150 parts of Herba Portulacae, 150 parts of Herba Echinops, 150 parts of Radix Chrysanthemi Indici, 150 parts of Caulis Spatholobi, 150 parts of Radix Codonopsis Daturae, 150 parts of Caulis Agrimoniae, 150 parts of Radix Gnaphalii, 50 parts of Herba Gnaphalii, 50 parts of Asarum, 150 parts of Cinnamomum camphora, 150 parts of Artemisia argyi, 150 parts of Rhizoma Coptidis, 50 parts of Radix Draconis, and 150 parts of Drynariae Zingiberis.

3. An external ointment for treating bone fractures and rheumatic pain, characterized in that: The invention comprises the external Chinese medicine composition according to claim 1 or 2 and auxiliary materials.

4. The external ointment according to claim 3, characterized in that The auxiliary materials include starch, brown sugar, honey, tea oil or sesame oil.

5. The external ointment according to claim 3, characterized in that, The auxiliary materials consist of starch, brown sugar, honey and tea oil; the mass fraction of starch in the external ointment is 2%; the mass fraction of brown sugar in the external ointment is 3%; the mass fraction of honey in the external ointment is 5%; and the mass fraction of tea oil in the external ointment is 10%.

6. The method for preparing the external ointment according to any one of claims 3 to 5, characterized in that: The steps include: Taking each raw medicinal material of the external Chinese medicine composition, crushing them and passing them through a 100-mesh sieve, and collecting the fine powder under the sieve; The fine powder is mixed with water, and soaked and decocted for the first time in sequence to obtain a uniform composition of the drug; After the first decoction, adding water for a second decoction; After the second decoction, adding auxiliary materials for boiling to obtain an external ointment; In the first decoction process, firstly heat to boil over high heat, and then continue to decoct over low heat for 20 to 30 minutes; In the second decoction process, the mixture is first boiled and then simmered over low heat for 20 minutes.

7. The preparation method according to claim 6, characterized in that: The soaking time is ≥30 min.

8. Use of the external Chinese medicine composition according to claim 1 or 2, the external ointment according to any one of claims 3 to 5, or the external ointment prepared by the preparation method according to claim 6 or 7 in the preparation of a drug for treating any of the following diseases: Bone fractures, bone fractures, bone sprains, bone displacement, bruises, bone hyperplasia, rheumatic numbness and joint pain.

9. The use according to claim 8, characterized in that: The fracture includes a new closed fracture or an old closed fracture.

10. Use of the external Chinese medicine composition according to claim 1 or 2, the external ointment according to any one of claims 3 to 5, or the external ointment prepared by the preparation method according to claim 6 or 7 in the preparation of a drug having any one of the following effects: replenishing qi and stopping bleeding, removing blood stasis and promoting new blood, and removing blood stasis and relieving pain.

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