A raw material processing device for sertraline hydrochloride tablets
By designing multiple sets of tower tray structures and flow diversion mechanisms, the problems of inconsistent steam temperature and the flow of raw material liquid into the gas channel during the distillation of sertraline hydrochloride are solved, and efficient distillation process and improvement of raw material purity are achieved.
Patent Information
- Application Number
- CN202510058677.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2025-01-15
- Publication Date
- 2025-06-10
- Estimated Expiration
- 2045-01-15
AI Technical Summary
In the prior art, during the distillation of sertraline hydrochloride sheets, the distribution of steam in the space above the tower tray is uneven, resulting in inconsistent steam temperature, affecting the distillation efficiency, and the raw material liquid flows into the gas channel, resulting in low efficiency.
A sertraline hydrochloride raw material treatment device is designed, adopting a multi-group tower tray structure, each tower tray includes a disk, a gas channel and a flow guide mechanism. The steam is in the same direction as the raw material liquid through the flow guide channel to ensure that the steam temperature in each layer of the tower tray is consistent, and the steam is directed to be output through the steam pipeline to avoid heat loss.
The distillation efficiency is improved, the steam is in full contact with the raw material liquid is ensured, heat loss is avoided and the materials in the liquid layer are merged into the liquid layer again, and the purity of the raw material is improved.
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Figure CN119455427B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of raw material processing, and particularly to a raw material processing device for sertraline hydrochloride tablets. Background Art
[0002] For the synthesis method of sertraline hydrochloride, it includes: asymmetric synthesis method, which can directly obtain cis-sertraline hydrochloride without the need for various resolutions; conventional chemical synthesis-separation method, that is, first obtaining the racemate of sertraline hydrochloride and then resolving to obtain the desired substance with a certain optical activity; asymmetric catalytic synthesis; chemical synthesis introducing a chiral source; before synthesis, it is necessary to purify and process the raw materials to turn the crude raw materials into high-quality products. Usually, methods such as rectification are used. By utilizing the different volatilities of each component in the mixture, each component is separated, and high-quality raw materials are obtained. Commonly used equipment includes plate rectification towers and packed rectification towers, etc. During the rectification process, the steam contacts the liquid layers on multiple trays in sequence, which is likely to cause temperature reduction of the steam, etc., and problems such as poor rectification efficiency on the upper trays occur. Therefore, there is an urgent need for a raw material processing device for sertraline hydrochloride tablets to solve the above problems. Summary of the Invention
[0003] The purpose of the present invention is to provide a raw material processing device for sertraline hydrochloride tablets, which can effectively solve the problems existing in the above-mentioned prior art.
[0004] To solve the above technical problems, the present invention adopts the following technical solutions: A raw material processing device for sertraline hydrochloride tablets, including a rectification tower for rectifying the raw materials. A plurality of groups of tray structures are arranged in the rectification tower. Each group of tray structures includes a plurality of trays arranged vertically. The tray includes:
[0005] A disc, on which a circular groove is provided. The height of the groove wall on the side of the circular groove close to the center is greater than the height of the groove wall on the side of the circular groove far from the center, and the groove wall on the side of the circular groove far from the center forms an overflow weir; a plurality of gas channels communicating with the lower tray are arranged in the circular groove. A flow guiding mechanism is installed at each gas channel in the circular groove. The flow guiding mechanism is configured to guide the air flow to flow into the circular groove from the bottom of the circular groove and restrict the raw material liquid in the circular groove from flowing into the gas channel; and
[0006] A through hole is concentrically opened at the center of the disc;
[0007] The steam pipeline includes a steam output channel and a steam delivery channel. The steam pipeline passes through the through holes of all the trays, and the steam output channel communicates with the space above each tray. The steam output channel is used to transport the gas above each tray to the top of the rectifying column. A diversion channel is provided in the tray, and the diversion channel is used to connect the steam delivery channel and the gas channel. The steam delivery channel is used to transport steam through the diversion channel into the gas channel.
[0008] Preferably, a drainage structure is installed between two adjacent trays. The top of the drainage structure surrounds the upper tray, and the bottom of the drainage structure extends to the area directly above the circular groove of the lower tray. The drainage structure is used to guide the overflowing raw material liquid in the upper tray to flow into the circular groove of the lower tray.
[0009] Preferably, an arc-shaped channel is provided at the bottom of the disc. The arc-shaped channel is inclined towards the side of the steam delivery channel and is communicated with the steam delivery channel. The arc-shaped channel is configured to guide the airflow overflowing from the circular groove into the steam delivery channel.
[0010] Preferably, the diversion mechanism includes:
[0011] An inner pipe, the bottom of the inner pipe is connected to the opening of the gas channel, the bottom end of the inner pipe extends upward, and the height of the top end of the inner pipe is not less than the height of the overflow weir;
[0012] An outer pipe, the outer pipe is sleeved on the inner pipe, and the top end of the outer pipe is blocked. The bottom end of the outer pipe is connected to the circular groove, and a number of steam overflow holes are provided at the bottom of the outer pipe where it is located in the circular groove.
[0013] Preferably, a cover plate is installed at the top end of the inner pipe, and the cover plate and the top end of the inner pipe are connected by an elastic member. The elastic member is configured to control the cover plate to block the top end of the inner pipe when not under force.
[0014] Preferably, a floating plate is slidably installed along the vertical direction on the outer side of the outer pipe. A drainage hole is provided on the side of the gas channel away from the inner pipe, and a blocking plate is installed at the drainage hole. The blocking plate is connected to the floating plate by a connecting rod. The floating plate is configured to drive the blocking plate to block the drainage hole through the connecting rod when the liquid height in the circular groove is not less than the height of the overflow weir; when the liquid height in the circular groove is less than the height of the overflow weir, drive the blocking plate to open the drainage hole through the connecting rod. A drainage trough is provided below the drainage hole, and the distal end of the drainage trough extends to the outside of the tray.
[0015] Preferably, a flow splitting structure is installed between the bottom ends of the steam output channel and the steam delivery channel. The flow splitting structure includes:
[0016] A diverter plate, the diverter plate is arranged in the steam delivery channel and is inclined toward one side of the steam output channel;
[0017] A diverter channel, the diverter channel being disposed between the steam output channel and the diverter plate and used for guiding the steam entering the diverter plate to flow into the steam output channel; and
[0018] The diversion channel is inclined vertically upward.
[0019] Preferably, a plurality of paddles are arranged in the circular groove, and a driving structure is installed in the tower plate, the driving structure is connected to the paddles, and the driving structure is used to drive the paddles to make circular motion and simultaneously drive the raw material liquid in the circular groove to flow circumferentially.
[0020] Preferably, the driving structure comprises:
[0021] A rotating disk is concentrically arranged at the through hole, and one end of each of the paddles is connected to the rotating disk;
[0022] A power chamber, wherein a turbine is installed in the power chamber and the turbine is coaxially connected to the rotating disk;
[0023] A drainage channel is arranged on the inner wall of the through hole, and one end of the drainage channel is connected to the steam delivery channel, and the other end of the drainage channel extends into the power chamber.
[0024] Preferably, the power chamber is arranged between the guide channel and the steam delivery channel, steam flows from the steam delivery channel into the power chamber, and flows from the power chamber into the guide channel, and the connection point between the guide channel and the steam delivery channel is staggered with the gas channel.
[0025] Beneficial effect: In the present invention, a plurality of groups of tower tray structures are arranged so that the raw material liquid flows through each layer of tower tray from top to bottom in sequence under the action of gravity and is discharged to the bottom of the distillation tower; the steam, driven by the pressure difference, passes through the gas channels of each layer of tower tray from bottom to top in sequence, and flows into the raw material liquid in the same direction through the guide mechanism, and a liquid layer of a certain depth is maintained on each layer of tower tray. The steam is dispersed into the liquid layer through the tower tray to carry out interphase contact mass transfer; wherein, the guide mechanism can guide the liquid to enter from the bottom of the liquid layer and prevent the liquid from flowing into the gas channel, and, in the present invention, a steam pipeline is arranged at the center of the disc, and the steam output channel and the steam delivery channel are arranged, so that the steam above each layer of tower tray can be guided directly toward the tower fixed output of the distillation tower. Compared with the traditional technology, it ensures that the temperature of the steam flowing into each layer of tower tray is consistent, and the heat loss caused by the layer-by-layer flow is avoided. Moreover, the steam passing through the liquid layer is directly output, which can prevent the substances in the liquid layer from being re-integrated into the liquid layer, thereby improving the distillation effect.
[0026] In addition, in the present invention, through the arrangement of the paddle and the driving structure, the steam entering can be utilized to drive the paddle to rotate, thereby driving the raw material liquid in the circular groove to be in a flowing state all the time during operation, so that the steam and the raw material liquid are in full contact. BRIEF DESCRIPTION OF THE DRAWINGS
[0027] The drawings are used to provide a further understanding of the present invention, and constitute a part of the specification. They are used together with the embodiments of the present invention to explain the present invention, and do not constitute a limitation to the present invention.
[0028] In the drawings:
[0029] Figure 1 is a schematic structural diagram of the raw material processing device of the present invention;
[0030] Figure 2 is a schematic structural diagram of a single group of tray structures in the rectification column of the present invention;
[0031] Figure 3 is a schematic structural diagram of another state of a single group of tray structures in the rectification column of the present invention;
[0032] Figure 4 is a schematic structural diagram of a single group of tray structures of the present invention;
[0033] Figure 5 is a front view of a single group of tray structures of the present invention;
[0034] Figure 6 is a schematic structural diagram of two trays of the present invention;
[0035] Figure 7 is a schematic structural diagram of a single tray of the present invention;
[0036] Figure 8 is a schematic structural diagram of the drainage structure of the present invention;
[0037] Figure 9 is a schematic structural diagram of the turbine of the present invention;
[0038] Figure 10 is a schematic structural diagram of a part of the steam pipeline of the present invention;
[0039] Reference numerals in the figure: 1, rectification column; 2, tray; 21, circular groove; 22, overflow weir; 23, gas channel; 24, through hole; 25, diversion channel; 26, arc channel; 3, feed inlet; 4, steam input pipeline; 5, reflux pipe; 61, inner pipe; 62, outer pipe; 63, steam overflow hole; 64, cover plate; 65, elastic member; 7, steam pipeline; 71, steam output channel; 72, steam delivery channel; 8, drainage structure; 91, shunt plate; 92, shunt channel; 10, floating plate; 11, drain hole; 12, plug plate; 13, connecting rod; 141, paddle; 142, turntable; 143, power chamber; 144, drainage channel; 145, turbine. Detailed implementation mode
[0040] The embodiments of the present invention will be described below with reference to the accompanying drawings in the embodiments of the present invention. The terms used in the embodiments of the present invention are only for explaining the specific embodiments of the present invention, and are not intended to limit the present invention. The embodiments of the present application will be described below with reference to the accompanying drawings.
[0041] Embodiment: As Figure 1 shown, a raw material treatment device for sertraline hydrochloride tablets includes a rectification column 1 for rectifying the raw materials. A plurality of groups of tray structures are arranged in the rectification column 1. Each group of tray structures includes a plurality of trays 2 arranged along the vertical direction. The raw material liquid enters from the feed inlet 3 in the middle of the rectification column 1 and flows to the trays 2. Under the action of gravity, the raw material liquid flows through each layer of trays 2 from top to bottom in sequence and is discharged at the bottom of the rectification column 1; the steam enters from the steam input pipeline 4 near the bottom of the rectification column 1. Under the push of the pressure difference, the steam passes through each layer of trays 2 from bottom to top in sequence and is discharged at the top of the rectification column 1; a reflux pipe 5 is arranged near the top of the rectification column 1. The raw material liquid discharged from the bottom of the rectification column 1 can enter again from the reflux pipe 5 according to needs and flow to the topmost tray 2;
[0042] Refer to Figures 2-6 shown, each group of tray structures includes a plurality of trays 2 arranged along the vertical direction. The tray 2 includes:
[0043] A disc. Refer to Figure 7 shown. A circular groove 21 is arranged on the disc. The height of the groove wall on the side of the circular groove 21 close to the center is greater than the height of the groove wall on the side of the circular groove 21 far from the center, and the groove wall on the side of the circular groove 21 far from the center forms an overflow weir 22; a plurality of gas channels 23 connecting to the lower tray 2 are arranged in the circular groove 21. A diversion mechanism is installed at each gas channel 23 in the circular groove 21. The diversion mechanism is configured to guide the air flow to flow into the circular groove 21 from the bottom of the circular groove 21 and restrict the raw material liquid in the circular groove 21 from flowing into the gas channel 23;
[0044] In a specific embodiment, based on the above, the flow guiding mechanism specifically includes an inner pipe 61 and an outer pipe 62. The bottom of the inner pipe 61 is connected to the opening of the gas passage 23. The bottom end of the inner pipe 61 extends upward, and the height of the top end of the inner pipe 61 is not less than the height of the overflow weir 22. The outer pipe 62 is sleeved on the inner pipe 61, and the top end of the outer pipe 62 is blocked. The bottom end of the outer pipe 62 is connected to the circular groove 21, and a plurality of steam overflow holes 63 are provided at the bottom of the outer pipe 62 located in the circular groove 21.
[0045] Through the cooperation of the above-mentioned inner pipe 61 and outer pipe 62, steam enters the inner pipe 61 from the gas passage 23, flows upward along the inner pipe 61, flows out from the top end of the inner pipe 61, and then flows downward along the gap between the inner pipe 61 and the outer pipe 62 until it flows out from the steam overflow holes 63, realizing the guiding of steam to flow out from the bottom of the circular groove 21 and preventing the liquid in the bottom of the circular groove 21 from flowing into the inner pipe 61.
[0046] Among them, based on the above, a cover plate 64 is installed at the top end of the inner pipe 61, and the cover plate 64 is connected to the top end of the inner pipe 61 through an elastic member 65. The elastic member 65 can adopt a spring structure. The elastic member 65 is configured to control the cover plate 64 to block the top end of the inner pipe 61 when not under force, that is, when there is no steam flow, under the elastic force of the elastic member 65, the cover plate 64 is controlled to block the top pipe of the inner pipe 61. In the case of steam being introduced, the cover plate 64 is driven to move upward by the pressure of the steam, thereby opening the opening at the top end of the inner pipe 61 so that steam can flow out from the top end of the inner pipe 61.
[0047] Refer to Figure 7 As shown, a through hole 24 is concentrically opened at the center of the disc; refer to Figures 2-3 And Figure 10 As shown, the tray structure further includes a steam pipe 7. The steam pipe 7 passes through the through holes 24 of all the trays 2, and the steam pipe 7 includes a steam output channel 71 and a steam delivery channel 72. The steam output channel 71 is communicated with the space above each tray 2. The steam output channel 71 is used to convey the gas above each tray 2 to the top of the distillation column 1. A flow guiding channel 25 is provided in the tray 2. The flow guiding channel 25 is used to connect the steam delivery channel 72 and the gas passage 23. The steam delivery channel 72 is used to convey steam into the gas passage 23 through the flow guiding channel 25.
[0048] Based on the above, refer to Figures 2-3 As shown, an arc-shaped channel 26 is provided at the bottom of the disc. The arc-shaped channel 26 is inclined toward the steam delivery channel 72 and is communicated with the steam delivery channel 72. The arc-shaped channel 26 is configured to guide the airflow overflowing from the circular groove 21 into the steam output channel 71.
[0049] Based on the above, during the rectification process, the steam is transported to each tray 2 through the steam output channel 71, and the steam is guided into the gas channel 23 through the diversion channel 25 and flows out from the steam overflow hole 63 of the diversion mechanism along the gas channel 23, ensuring that the steam temperature flowing into each tray 2 is consistent, avoiding heat loss caused by layer-by-layer flow, and under the guidance of the arc-shaped channel 26, the gas produced on each tray 2 will flow towards the steam transport channel 72 along the arc-shaped channel 26, and the steam passing through the liquid layer is directly output through the steam transport channel 72, which can prevent the substances in the liquid layer from re-dissolving into the liquid layer and improve the rectification effect.
[0050] Based on the above, a drainage structure 8 is installed between two adjacent trays 2. The top of the drainage structure 8 surrounds the upper tray 2, and the bottom of the drainage structure 8 extends to the area directly above the circular groove 21 of the lower tray 2. The drainage structure 8 is used to guide the overflowing raw material liquid in the upper tray 2 to flow into the circular groove 21 of the lower tray 2.
[0051] Reference Figures 2-8 As shown, the top end of the drainage structure 8 is an annular sleeve structure, and the bottom is a funnel structure. The liquid flowing out from the overflow weir 22 is collected through the top end of the drainage structure 8 and flows into the circular groove 21 of the lower tray 2 along the funnel structure at the bottom end of the drainage structure 8, realizing the layer-by-layer downward flow of the liquid.
[0052] In another specific embodiment, based on the above, reference Figure 2 As shown, a flow splitting structure is installed between the bottom ends of the steam output channel 71 and the steam transport channel 72. The flow splitting structure includes a flow splitting plate 91 and a flow splitting channel 92; the flow splitting plate 91 is arranged in the steam transport channel 72 and is inclined towards the steam output channel 71; the flow splitting channel 92 is arranged between the steam output channel 71 and the flow splitting plate 91 and is used to guide the steam entering the flow splitting plate 91 to flow into the steam output channel 71; and the flow splitting channel 92 is inclined vertically upwards; after the steam enters through the steam pipe 7, it first enters the steam transport channel 72, and then part of the steam will flow towards the flow splitting channel 92 along the flow splitting plate 91 and flow through the flow splitting channel 92 into the steam output channel 71, and the flow splitting channel 92 is inclined, so the steam initially flowing into the steam output channel 71 has the power to flow upwards, and the steam flowing into each tray 2 can be driven by this part of the steam to flow towards the rectification tower 1.
[0053] In another specific embodiment, reference Figure 2 and Figure 7As shown, based on the above, a floating plate 10 is slidably installed on the outer side of the outer tube 62 along the vertical direction, a leakage hole 11 is provided on the side of the gas channel 23 away from the inner tube 61, and a blocking plate 12 is installed at the leakage hole 11. The blocking plate 12 is connected to the floating plate 10 through a connecting rod 13. The floating plate 10 is configured to drive the blocking plate 12 to block the leakage hole 11 through the connecting rod 13 when the liquid height in the circular groove 21 is not less than the height of the overflow weir 22; when the liquid height in the circular groove 21 is less than the height of the overflow weir 22, The plugging plate 12 is driven by the connecting rod 13 to open the leakage hole 11. A drainage channel is arranged below the leakage hole 11, and the far end of the drainage channel extends to the outside of the tower plate 2. When the distillation is completed, due to the existence of the overflow weir 22, a certain amount of liquid will remain in the circular groove 21. At this time, the floating plate 10 will sink with the liquid level, and the plugging plate 12 will be pushed down by the connecting rod 13, so as to open the leakage hole 11. The liquid in the circular groove 21 will slowly flow out from the leakage hole 11 and flow into the drainage channel below. Figure 2 As shown, one end of the drainage channel extends to the top of the drainage structure 8 and flows along the drainage structure 8 into the next tower tray 2, thereby realizing the automatic processing function of the liquid retained in each tower tray 2.
[0054] In another specific embodiment, referring to Figure 7 As shown, a plurality of paddles 141 are arranged in the circular groove 21, and a driving structure is installed in the tower plate 2. The driving structure is connected to the paddles 141, and the driving structure is used to drive the paddles 141 to make circular motion, and at the same time drive the raw material liquid in the circular groove 21 to flow circumferentially.
[0055] For the driving structure, in a specific embodiment, refer to Figure 2 and Figure 9 As shown, the driving structure includes a turntable 142, a power chamber 143 and a drainage channel 144. The turntable 142 and the power chamber 143 are both installed at the through hole 24 near the tower plate 2. One end of each paddle 141 is connected to the turntable 142 and can rotate with the turntable 142, thereby driving each paddle 141 to rotate. In order to improve the paddle effect of the paddle 141, the size of the paddle 141 fits the width of the entire circular groove 21, and a notch is provided on the paddle 141. The notch is used to avoid each guide structure. A turbine 145 is installed in the power chamber 143, and the turbine 145 is coaxially connected to the turntable 142; the drainage channel 144 is arranged on the inner wall of the through hole 24, and one end of the drainage channel 144 is connected to the steam delivery channel 72, and the other end extends into the power chamber 143.
[0056] Based on the above, the steam in the steam delivery channel 72 is introduced into the power chamber 143 through the drainage channel 144, and the turbine 145 is driven to rotate by the pressure of the steam, thereby driving the turntable 142 to rotate, and then driving each paddle 141 to rotate, disturbing the liquid in the circular groove 21, so that the liquid can flow circumferentially, avoiding the limitation of the position and number of the gas channel 23, and coordinating the vertical flow of the liquid to further improve the contact effect between the liquid and the steam in the entire circular groove 21.
[0057] Among them, reference Figure 2 As shown, the power chamber 143 is arranged between the guide channel 25 and the steam delivery channel 72. The steam flows into the power chamber 143 from the steam delivery channel 72, and flows from the power chamber 143 into the guide channel 25. The connection point between the guide channel 144 and the steam delivery channel 72 is staggered with the gas channel 23. The steam entering the power chamber 143 will flow in the direction of the gas passage, and while guiding the airflow to flow into the guide channel 25, the turbine 145 can be rotated.
[0058] The embodiments of the present invention are described in detail above in conjunction with the accompanying drawings, but the present invention is not limited to the above embodiments. For ordinary technicians in this technical field, after knowing the contents recorded in the present invention, they can make several equivalent changes and substitutions without departing from the principle of the present invention. These equivalent changes and substitutions should also be regarded as belonging to the protection scope of the present invention.
Claims
1. A raw material processing device for sertraline hydrochloride tablets, comprising a distillation tower for distilling raw materials, wherein the distillation tower is provided with a plurality of groups of tray structures, each group of the tray structures comprises a plurality of trays arranged in a vertical direction, characterized in that: The tower tray comprises: a disc, wherein a circular groove is arranged on the disc, the groove wall height of the circular groove near the center side is greater than the groove wall height of the circular groove away from the center side, and the groove wall of the circular groove away from the center side forms an overflow weir; a plurality of gas channels connected to the lower tower plate are arranged in the circular groove, and a flow guide mechanism is installed in each gas channel in the circular groove, and the flow guide mechanism is configured to guide the gas flow from the bottom of the circular groove into the circular groove, and restrict the raw material liquid in the circular groove from flowing into the gas channel; and A through hole is concentrically formed at the center of the disc; A steam pipe comprises a steam output channel and a steam delivery channel, wherein the steam pipe passes through the through holes of all the tower plates, and the steam output channel is connected with the space above each tower plate, and the steam output channel is used to deliver the gas above each tower plate to the top of the distillation tower, and a guide channel is opened in the tower plate, and the guide channel is used to connect the steam delivery channel and the gas channel, and the steam delivery channel is used to deliver steam to the gas channel through the guide channel.
2. The sertraline hydrochloride tablets raw material processing device according to claim 1, characterized in that: A drainage structure is installed between two adjacent tower plates, the top of the drainage structure surrounds the upper tower plate, and the bottom of the drainage structure extends to the area directly above the circular groove of the lower tower plate. The drainage structure is used to guide the overflowing raw material liquid in the upper tower plate to flow into the circular groove of the lower tower plate.
3. The sertraline hydrochloride tablet raw material processing device according to claim 1, characterized in that: An arc-shaped channel is provided at the bottom of the disc, the arc-shaped channel is inclined toward one side of the steam delivery channel, and the arc-shaped channel is connected to the steam delivery channel. The arc-shaped channel is configured to guide the airflow overflowing from the circular groove to flow into the steam delivery channel.
4. The sertraline hydrochloride tablets raw material processing device according to claim 1, characterized in that: The flow guiding mechanism comprises: An inner tube, wherein the bottom of the inner tube is connected to the opening of the gas passage, the bottom end of the inner tube extends upward, and the height of the top end of the inner tube is not less than the height of the overflow weir; The outer tube is sleeved on the inner tube, the top of the outer tube is blocked, the bottom of the outer tube is connected to the circular groove, and the outer tube is provided with a plurality of steam overflow holes at the bottom of the circular groove.
5. The sertraline hydrochloride tablets raw material processing device according to claim 4, characterized in that: A cover plate is installed at the top end of the inner tube, and the cover plate is connected to the top end of the inner tube via an elastic member, and the elastic member is configured to control the cover plate to block the top end of the inner tube when no force is applied.
6. A sertraline hydrochloride tablet raw material processing device according to claim 4 or 5, characterized in that: A floating plate is installed on the outer side of the outer tube for sliding along the vertical direction, a leakage hole is provided on the side of the gas channel away from the inner tube, a blocking plate is installed at the leakage hole, and the blocking plate is connected to the floating plate through a connecting rod, and the floating plate is configured to block the leakage hole by driving the blocking plate through the connecting rod when the liquid height in the circular groove is not less than the overflow weir height; when the liquid height in the circular groove is less than the overflow weir height, the blocking plate is driven by the connecting rod to open the leakage hole, and a drainage channel is provided below the leakage hole, and the far end of the drainage channel extends to the outside of the tower plate.
7. The sertraline hydrochloride tablet raw material processing device according to claim 1, characterized in that: A flow dividing structure is installed between the bottom end of the steam output channel and the steam delivery channel, and the flow dividing structure includes: A diverter plate, the diverter plate is arranged in the steam delivery channel and is inclined toward one side of the steam output channel; A diverter channel, the diverter channel being disposed between the steam output channel and the diverter plate and used for guiding the steam entering the diverter plate to flow into the steam output channel; and The diversion channel is inclined vertically upward.
8. The sertraline hydrochloride tablets raw material processing device according to claim 1, characterized in that: A plurality of paddles are arranged in the circular groove, and a driving structure is installed in the tower plate. The driving structure is connected to the paddles and is used to drive the paddles to make circular motion and drive the raw material liquid in the circular groove to flow circumferentially.
9. The sertraline hydrochloride tablets raw material processing device according to claim 8, characterized in that: The driving structure comprises: A rotating disk is concentrically arranged at the through hole, and one end of each of the paddles is connected to the rotating disk; A power chamber, wherein a turbine is installed in the power chamber and the turbine is coaxially connected to the rotating disk; A drainage channel is arranged on the inner wall of the through hole, and one end of the drainage channel is connected to the steam delivery channel, and the other end of the drainage channel extends into the power chamber.
10. The sertraline hydrochloride tablets raw material processing device according to claim 9, characterized in that: The power chamber is arranged between the guide channel and the steam delivery channel, steam flows into the power chamber from the steam delivery channel, and flows from the power chamber into the guide channel, and the connection point between the guide channel and the steam delivery channel is staggered with the gas channel.
Citation Information
Patent Citations
Improvements in or relating to vacuum distillation
GB315186A
Improvements relating to dephlegmators of the bubble-tray type
GB554655A